Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway.
Nature Communications
González, Lorena L; Díaz, Lucía L; Pous, Joan J; Baginski, Blazej B; Duran-Corbera, Anna A; Scarpa, Margherita M; Brun-Heath, Isabelle I; Igea, Ana A; Martin-Malpartida, Pau P; Ruiz, Lidia L; Pallara, Chiara C; Esguerra, Mauricio M; Colizzi, Francesco F; Mayor-Ruiz, Cristina C; Biondi, Ricardo M RM; Soliva, Robert R; Macias, Maria J MJ; Orozco, Modesto M; Nebreda, Angel R AR
Early serial circulating tumor DNA sequencing predicts the efficacy of chemohormonal therapy in patients with metastatic hormone-sensitive prostate cancer.
The Swedish childhood tumor biobank: systematic collection and molecular characterization of all pediatric CNS and other solid tumors in Sweden.
Journal Of Translational Medicine
Díaz de Ståhl, Teresita T; Shamikh, Alia A; Mayrhofer, Markus M; Juhos, Szilvester S; Basmaci, Elisa E; Prochazka, Gabriela G; Garcia, Maxime M; Somarajan, Praveen Raj PR; Zielinska-Chomej, Katarzyna K; Illies, Christopher C; Øra, Ingrid I; Siesjö, Peter P; Sandström, Per-Erik PE; Stenman, Jakob J; Sabel, Magnus M; Gustavsson, Bengt B; Kogner, Per P; Pfeifer, Susan S; Ljungman, Gustaf G; Sandgren, Johanna J; Nistér, Monica M
Quantification of capture efficiency, purity, and single-cell isolation in the recovery of circulating melanoma cells from peripheral blood by dielectrophoresis.
Lab On A Chip
Chen, Han H; Osman, Sommer Y SY; Moose, Devon L DL; Vanneste, Marion M; Anderson, Jared L JL; Henry, Michael D MD; Anand, Robbyn K RK
Circulating tumor DNA reveals mechanisms of lorlatinib resistance in patients with relapsed/refractory ALK-driven neuroblastoma.
Nature Communications
Berko, Esther R ER; Witek, Gabriela M GM; Matkar, Smita S; Petrova, Zaritza O ZO; Wu, Megan A MA; Smith, Courtney M CM; Daniels, Alex A; Kalna, Joshua J; Kennedy, Annie A; Gostuski, Ivan I; Casey, Colleen C; Krytska, Kateryna K; Gerelus, Mark M; Pavlick, Dean D; Ghazarian, Susan S; Park, Julie R JR; Marachelian, Araz A; Maris, John M JM; Goldsmith, Kelly C KC; Radhakrishnan, Ravi R; Lemmon, Mark A MA; Mossé, Yaël P YP
Addressing resistance to PD-1/PD-(L)1 pathway inhibition: considerations for combinatorial clinical trial designs.
Journal For Immunotherapy Of Cancer
Zhang, Tian T; Forde, Patrick M PM; Sullivan, Ryan J RJ; Sharon, Elad E; Barksdale, Elizabeth E; Selig, Wendy W; Ebbinghaus, Scot S; Fusaro, Gina G; Gunenc, Damla D; Battle, Dena D; Burns, Robyn R; Hurlbert, Marc S MS; Stewart, Mark M; Atkins, Michael B MB
ESTIMation of the ABiLity of prophylactic central compartment neck dissection to modify outcomes in low-risk differentiated thyroid cancer: a prospective randomized trial.
Trials
Hartl, Dana D; Godbert, Yann Y; Carrat, Xavier X; Bardet, Stéphane S; Lasne-Cardon, Audrey A; Vera, Pierre P; Ilies, Elena E; Zerdoud, Slimane S; Sarini, Jérôme J; Zalzali, Mohamad M; La Manna, Luigi L; Schneegans, Olivier O; Kelly, Antony A; Kauffmann, Philppe P; Rodien, Patrice P; Brunaud, Laurent L; Grunenwald, Solange S; Housseau, Elie E; Laghouati, Salim S; Bouvet, Nathalie N; Lecerf, Elodie E; Hadoux, Julien J; Lamartina, Livia L; Schlumberger, Martin M; Borget, Isabelle I
Differential microRNA expression for diagnosis and prognosis of papillary thyroid cancer.
Frontiers In Medicine
Ruiz-Pozo, Viviana A VA; Cadena-Ullauri, Santiago S; Guevara-Ramírez, Patricia P; Paz-Cruz, Elius E; Tamayo-Trujillo, Rafael R; Zambrano, Ana Karina AK
Dabrafenib plus trametinib in BRAFV600E-mutated rare cancers: the phase 2 ROAR trial.
Nature Medicine
Subbiah, Vivek V; Kreitman, Robert J RJ; Wainberg, Zev A ZA; Gazzah, Anas A; Lassen, Ulrik U; Stein, Alexander A; Wen, Patrick Y PY; Dietrich, Sascha S; de Jonge, Maja J A MJA; Blay, Jean-Yves JY; Italiano, Antoine A; Yonemori, Kan K; Cho, Daniel C DC; de Vos, Filip Y F L FYFL; Moreau, Philippe P; Fernandez, Elena Elez EE; Schellens, Jan H M JHM; Zielinski, Christoph C CC; Redhu, Suman S; Boran, Aislyn A; Passos, Vanessa Q VQ; Ilankumaran, Palanichamy P; Bang, Yung-Jue YJ
Hairy Cell Leukemia (HCL) Presenting with Joint Swelling: Case Report and Literature Review of a Rare Rheumatological Manifestation of a Hematological Disease.
Discovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones.
Journal Of Medicinal Chemistry
Harnden, Alice C AC; Davis, Owen A OA; Box, Gary M GM; Hayes, Angela A; Johnson, Louise D LD; Henley, Alan T AT; de Haven Brandon, Alexis K AK; Valenti, Melanie M; Cheung, Kwai-Ming J KJ; Brennan, Alfie A; Huckvale, Rosemary R; Pierrat, Olivier A OA; Talbot, Rachel R; Bright, Michael D MD; Akpinar, Hafize Aysin HA; Miller, Daniel S J DSJ; Tarantino, Dalia D; Gowan, Sharon S; de Klerk, Selby S; McAndrew, Peter Craig PC; Le Bihan, Yann-Vaï YV; Meniconi, Mirco M; Burke, Rosemary R; Kirkin, Vladimir V; van Montfort, Rob L M RLM; Raynaud, Florence I FI; Rossanese, Olivia W OW; Bellenie, Benjamin R BR; Hoelder, Swen S
Design, Synthesis, In Vitro and In Vivo Characterization of CDC42 GTPase Interaction Inhibitors for the Treatment of Cancer.
Journal Of Medicinal Chemistry
Brindani, Nicoletta N; Vuong, Linh M LM; Acquistapace, Isabella Maria IM; La Serra, Maria Antonietta MA; Ortega, José Antonio JA; Veronesi, Marina M; Bertozzi, Sine Mandrup SM; Summa, Maria M; Girotto, Stefania S; Bertorelli, Rosalia R; Armirotti, Andrea A; Ganesan, Anand K AK; De Vivo, Marco M
Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Deep genomic characterization highlights complexities and prognostic markers of pediatric acute myeloid leukemia.
Communications Biology
Cheng, Chi-Keung CK; Yung, Yuk-Lin YL; Chan, Hoi-Yun HY; Leung, Kam-Tong KT; Chan, Kathy Y Y KYY; Leung, Alex W K AWK; Cheng, Frankie W T FWT; Li, Chi-Kong CK; Wan, Thomas S K TSK; Luo, Xi X; Pitts, Herbert-Augustus HA; Cheung, Joyce S JS; Chan, Natalie P H NPH; Ng, Margaret H L MHL
Publication Date: 2023-03-31
Variant appearance in text: BRAF: 1799T>A; V600E; rs113488022
Modulating fast skeletal muscle contraction protects skeletal muscle in animal models of Duchenne muscular dystrophy.
The Journal Of Clinical Investigation
Russell, Alan J AJ; DuVall, Mike M; Barthel, Benjamin B; Qian, Ying Y; Peter, Angela K AK; Newell-Stamper, Breanne L BL; Hunt, Kevin K; Lehman, Sarah J SJ; Madden, Molly R MR; Schlachter, Stephen T ST; Robertson, Benjamin D BD; Van Deusen, Ashleigh A; Rodriguez, Hector M HM; Vera, Carlos D CD; Su, Yu Y; Claflin, Dennis R DR; Brooks, Susan V SV; Nghiem, Peter P PP; Rutledge, Alexis A; Juehne, Twlya I TI; Yu, Jinsheng J; Barton, Elisabeth R ER; Luo, Yangyi E YE; Patsalos, Andreas A; Nagy, Laszlo L; Sweeney, H Lee HL; Leinwand, Leslie A LA; Koch, Kevin K
Association of DNA Promoter Methylation and BRAF Mutation in Thyroid Cancer.
Current Oncology (Toronto, Ont.)
Jasmine, Farzana F; Aschebrook-Kilfoy, Briseis B; Rahman, Mohammad M MM; Zaagman, Garrett G; Grogan, Raymon H RH; Kamal, Mohammed M; Ahsan, Habibul H; Kibriya, Muhammad G MG
Neuroblastoma arises in early fetal development and its evolutionary duration predicts outcome.
Nature Genetics
Körber, Verena V; Stainczyk, Sabine A SA; Kurilov, Roma R; Henrich, Kai-Oliver KO; Hero, Barbara B; Brors, Benedikt B; Westermann, Frank F; Höfer, Thomas T
Publication Date: 2023-03-27
Variant appearance in text: BRAF: V600E; rs113488022
Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non-small Cell Lung Cancer.
Cancer Research Communications
Frank, Malene S MS; Andersen, Christina S A CSA; Ahlborn, Lise B LB; Pallisgaard, Niels N; Bodtger, Uffe U; Gehl, Julie J
Clinical Outcomes of Stereotactic Radiosurgery-Related Radiation Necrosis in Patients with Intracranial Metastasis from Melanoma.
Clinical Medicine Insights. Oncology
Thomson, Holly M HM; Fortin Ensign, Shannon P SP; Edmonds, Victoria S VS; Sharma, Akanksha A; Butterfield, Richard J RJ; Schild, Steven E SE; Ashman, Jonathan B JB; Zimmerman, Richard S RS; Patel, Naresh P NP; Bryce, Alan H AH; Vora, Sujay A SA; Sio, Terence T TT; Porter, Alyx B AB
Ganglioglioma deep transcriptomics reveals primitive neuroectoderm neural precursor-like population.
Acta Neuropathologica Communications
Regal, Joshua A JA; Guerra García, María E ME; Jain, Vaibhav V; Chandramohan, Vidyalakshmi V; Ashley, David M DM; Gregory, Simon G SG; Thompson, Eric M EM; López, Giselle Y GY; Reitman, Zachary J ZJ