TIGIT T cell immunoreceptor with Ig and ITIM domains

Canonical transcript: NM_173799

29 unique variant annotations were identified in 28 publications

Variant ID cDot pDot Consequence Exon Intron Reference Count
3-114012943-GG-AC c.35_36delinsAC p.Gly12Asp Missense 1/4 - 3
3-114012943-G-T c.35G>T p.Gly12Val Missense 1/4 - 2
3-114014433-GCA-TTT c.103_105delinsTTT p.Ala35Phe Missense 2/4 - 1
3-114014454-AT-GA c.124_125delinsGA p.Ile42Asp Missense 2/4 - 1
3-114014454-AT-GC c.124_125delinsGC p.Ile42Ala Missense 2/4 - 1
3-114014496-CA-GC c.166_167delinsGC p.Gln56Ala Missense 2/4 - 1
3-114014497-A-G c.167A>G p.Gln56Arg Missense 2/4 - 1
3-114014529-GC-TT c.199_200delinsTT p.Ala67Phe Missense 2/4 - 1
3-114014535-T-A c.205T>A p.Cys69Ser Missense 2/4 - 1
3-114014536-G-C c.206G>C p.Cys69Ser Missense 2/4 - 1
3-114014538-AA-GC c.208_209delinsGC p.Asn70Ala Missense 2/4 - 1
3-114014539-AT-GG c.209_210delinsGG p.Asn70Arg Missense 2/4 - 1
3-114014551-G-C c.221G>C p.Gly74Ala Missense 2/4 - 1
3-114014599-G-C c.269G>C p.Gly90Ala Missense 2/4 - 1
3-114014600-C-T c.270C>T p.Gly90Gly Synonymous 2/4 - 1
3-114014664-A-G c.334A>G p.Thr112Ala Missense 2/4 - 1
3-114014667-TA-CG c.337_338delinsCG p.Tyr113Arg Missense 2/4 - 1
3-114014667-TA-GC c.337_338delinsGC p.Tyr113Ala Missense 2/4 - 2
3-114014670-C-G c.340C>G p.Pro114Ala Missense 2/4 - 1
3-114016047-T-C c.391+1326T>C - IntronicSNV - 2/3 1
3-114018467-C-T c.415C>T p.Gln139* Nonsense 3/4 - 1
3-114018982-A-G c.498+432A>G - IntronicSNV - 3/3 1
3-114026005-T-TT c.499-737dup - IntronicInsertion - 3/3 1
3-114026916-TA-GC c.673_674delinsGC p.Tyr225Ala Missense 4/4 - 3
3-114026922-AAT-CAA c.679_681delinsCAA p.Asn227Gln Missense 4/4 - 1
3-114026923-A-G c.680A>G p.Asn227Ser Missense 4/4 - 1
3-114026934-TA-GC c.691_692delinsGC p.Tyr231Ala Missense 4/4 - 3
3-114026943-CT-GC c.700_701delinsGC p.Leu234Ala Missense 4/4 - 1
3-114028633-G-A c.*1655G>A - 3-UTRSNV 4/4 - 1