BDNF brain derived neurotrophic factor

Annotation transcript: NM_001709.5

165 unique variant annotations were identified in 489 publications

Variant ID cDot pDot Consequence Exon Intron Reference Count
11-27679378-C-T c.734G>A p.R245K Missense 2/2 - 1
11-27679392-TG-CA c.719_720inv p.T240M Missense 2/2 - 1
11-27679392-TG-GT c.719_720delinsAC p.T240N Missense 2/2 - 1
11-27679393-G-C c.719C>G p.T240R Missense 2/2 - 1
11-27679421-T-C c.691A>G p.I231V Missense 2/2 - 2
11-27679438-CT-TG c.673_674delinsCA p.R225Q Missense 2/2 - 1
11-27679447-CT-GC c.664_665delinsGC p.S222A Missense 2/2 - 1
11-27679451-C-A c.661G>T p.D221Y Missense 2/2 - 1
11-27679473-C-T c.639G>A p.S213= Synonymous 2/2 - 1
11-27679486-C-T c.626G>A p.R209Q Missense 2/2 - 1
11-27679504-TG-AA c.607_608delinsTT p.H203F Missense 2/2 - 1
11-27679519-C-T c.593G>A p.G198D Missense 2/2 - 1
11-27679522-C-T c.590G>A p.R197K Missense 2/2 - 1
11-27679522-CT-TG c.589_590delinsCA p.R197Q Missense 2/2 - 1
11-27679525-CA-GT c.586_587delinsAC p.C196T Missense 2/2 - 1
11-27679535-T-C c.577A>G p.K193E Missense 2/2 - 1
11-27679543-C-A c.569G>T p.G190V Missense 2/2 - 1
11-27679555-CA-GC c.556_557delinsGC p.C186A Missense 2/2 - 1
11-27679564-T-A c.548A>T p.E183V Missense 2/2 - 1
11-27679565-C-T c.547G>A p.E183K Missense 2/2 - 3
11-27679589-C-T c.523G>A p.G175S Missense 2/2 - 1
11-27679592-T-G c.520A>C p.K174Q Missense 2/2 - 1
11-27679610-C-T c.502G>A p.E168K Missense 2/2 - 1
11-27679614-GAC-CAT c.496_498delinsATG p.V166M Missense 2/2 - 4
11-27679632-CG-AC c.479_480delinsGT p.S160C Missense 2/2 - 1
11-27679633-GA-TC c.478_479inv p.S160E Missense 2/2 - 1
11-27679634-A-C c.478T>G p.S160A Missense 2/2 - 1
11-27679640-C-T c.472G>A p.D158N Missense 2/2 - 1
11-27679662-T-A c.450A>T p.A150= Synonymous 2/2 - 3
11-27679663-G-A c.449C>T p.A150V Missense 2/2 - 1
11-27679665-C-T c.447G>A p.T149= Synonymous 2/2 - 1
11-27679666-G-A c.446C>T p.T149M Missense 2/2 - 1
11-27679666-G-C c.446C>G p.T149R Missense 2/2 - 1
11-27679668-TAC-CAT c.442_444delinsATG p.V148M Missense 2/2 - 3
11-27679669-A-C c.443T>G p.V148G Missense 2/2 - 1
11-27679670-C-T c.442G>A p.V148I Missense 2/2 - 2
11-27679672-C-T c.440G>A p.W147* Nonsense 2/2 - 1
11-27679677-A-C c.435T>G p.S145R Missense 2/2 - 1
11-27679677-A-T c.435T>A p.S145R Missense 2/2 - 1
11-27679679-T-G c.433A>C p.S145R Missense 2/2 - 1
11-27679684-CT-GC c.427_428delinsGC p.S143A Missense 2/2 - 1
11-27679691-A-C c.421T>G p.C141G Missense 2/2 - 2
11-27679696-C-T c.416G>A p.S139N Missense 2/2 - 1
11-27679702-T-C c.410A>G p.E137G Missense 2/2 - 1
11-27679711-CG-TC c.400_401delinsGA p.R134D Missense 2/2 - 2
11-27679718-G-T c.394C>A p.P132T Missense 2/2 - 1
11-27679723-GA-TC c.388_389inv p.S130D Missense 2/2 - 1
11-27679723-G-C c.389C>G p.S130C Missense 2/2 - 1
11-27679724-A-C c.388T>G p.S130A Missense 2/2 - 1
11-27679730-G-A c.382C>T p.R128C Missense 2/2 - 1
11-27679731-CCG-GTC c.379_381delinsGAC p.R127D Missense 2/2 - 1
11-27679732-C-A c.380G>T p.R127L Missense 2/2 - 4
11-27679738-C-A c.374G>T p.R125M Missense 2/2 - 4
11-27679739-T-A c.373A>T p.R125W Missense 2/2 - 3
11-27679742-T-C c.370A>G p.M124V Missense 2/2 - 1
11-27679749-GTT-TTG c.361_363delinsCAA p.N121Q Missense 2/2 - 1
11-27679765-T-A c.347A>T p.Y116F Missense 2/2 - 1
11-27679775-A-G c.337T>C p.Y113H Missense 2/2 - 1
11-27679778-C-T c.334G>A p.E112K Missense 2/2 - 1
11-27679783-AG-GC c.328_329delinsGC p.L110A Missense 2/2 - 1
11-27679791-G-C c.321C>G p.L107= Synonymous 2/2 - 1
11-27679793-G-A c.319C>T p.L107F Missense 2/2 - 1
11-27679796-G-C c.316C>G p.L106V Missense 2/2 - 1
11-27679810-G-C c.302C>G p.P101R Missense 2/2 - 1
11-27679810-G-T c.302C>A p.P101H Missense 2/2 - 1
11-27679811-G-A c.301C>T p.P101S Missense 2/2 - 1
11-27679812-CA-GT c.299_300delinsAC p.V100D Missense 2/2 - 7
11-27679822-CT-GC c.289_290delinsGC p.S97A Missense 2/2 - 1
11-27679849-TC-AA c.262_263delinsTT p.D88F Missense 2/2 - 1
11-27679851-T-A c.261A>T p.A87= Synonymous 2/2 - 1
11-27679851-T-C c.261A>G p.A87= Synonymous 2/2 - 1
11-27679851-T-G c.261A>C p.A87= Synonymous 2/2 - 1
11-27679851-TG-GT c.260_261delinsAC p.A87D Missense 2/2 - 2
11-27679854-G-C c.258C>G p.D86E Missense 2/2 - 1
11-27679854-G-T c.258C>A p.D86E Missense 2/2 - 1
11-27679858-T-A c.254A>T p.K85M Missense 2/2 - 2
11-27679858-T-C c.254A>G p.K85R Missense 2/2 - 2
11-27679858-TT-GC c.253_254delinsGC p.K85A Missense 2/2 - 2
11-27679866-TTC-ACA c.244_246delinsTGT p.E82C Missense 2/2 - 1
11-27679867-T-G c.245A>C p.E82A Missense 2/2 - 1
11-27679869-TTC-AAA c.241_243delinsTTT p.E81F Missense 2/2 - 1
11-27679871-C-T c.241G>A p.E81K Missense 2/2 - 1
11-27679876-GG-AC c.235_236delinsGT p.P79V Missense 2/2 - 1
11-27679879-CG-GC c.232_233delinsGC p.R78A Missense 2/2 - 1
11-27679887-C-A c.225G>T p.Q75H Missense 2/2 - 1
11-27679890-G-A c.222C>T p.D74= Synonymous 2/2 - 1
11-27679892-C-T c.220G>A p.D74N Missense 2/2 - 1
11-27679893-C-T c.219G>A p.E73= Synonymous 2/2 - 1
11-27679903-AG-GC c.208_209delinsGC p.L70A Missense 2/2 - 1
11-27679905-C-T c.207G>A p.E69= Synonymous 2/2 - 1
11-27679911-T-A c.201A>T p.I67= Synonymous 2/2 - 1
11-27679911-T-G c.201A>C p.I67= Synonymous 2/2 - 1
11-27679914-C-A c.198G>T p.V66= Synonymous 2/2 - 76
11-27679914-CAC-GTT c.196_198delinsAAC p.V66N Missense 2/2 - 10
11-27679914-C-G c.198G>C p.V66= Synonymous 2/2 - 76
11-27679914-C-T c.198G>A p.V66= Synonymous 2/2 - 76
11-27679915-AC-GG c.196_197delinsCC p.V66P Missense 2/2 - 2
11-27679916-C-T c.196G>A p.V66M Missense 2/2 - 2513
11-27679920-T-A c.192A>T p.E64D Missense 2/2 - 3
11-27679920-T-G c.192A>C p.E64D Missense 2/2 - 3
11-27679930-T-C c.182A>G p.D61G Missense 2/2 - 1
11-27679931-C-A c.181G>T p.D61Y Missense 2/2 - 1
11-27679948-C-G c.164G>C p.G55A Missense 2/2 - 1
11-27679955-A-G c.157T>C p.S53P Missense 2/2 - 1
11-27679959-TGC-AAA c.151_153delinsTTT p.A51F Missense 2/2 - 1
11-27679959-TGC-ACA c.151_153delinsTGT p.A51C Missense 2/2 - 1
11-27679960-G-T c.152C>A p.A51E Missense 2/2 - 1
11-27679962-CTT-GTC c.148_150delinsGAC p.K50D Missense 2/2 - 1
11-27679963-T-C c.149A>G p.K50R Missense 2/2 - 1
11-27679977-G-C c.135C>G p.S45R Missense 2/2 - 1
11-27679977-G-T c.135C>A p.S45R Missense 2/2 - 1
11-27679979-T-G c.133A>C p.S45R Missense 2/2 - 2
11-27679988-T-C c.124A>G p.T42A Missense 2/2 - 1
11-27679991-C-G c.121G>C p.G41R Missense 2/2 - 1
11-27679998-CCG-GTC c.112_114delinsGAC p.R38D Missense 2/2 - 1
11-27680002-A-G c.110T>C p.V37A Missense 2/2 - 1
11-27680007-TGG-CAT c.103_105delinsATG p.P35M Missense 2/2 - 1
11-27680008-GG-CC c.103_104inv p.P35G Missense 2/2 - 21
11-27680014-GC-AA c.97_98delinsTT p.A33F Missense 2/2 - 1
11-27680014-GC-CA c.97_98delinsTG p.A33C Missense 2/2 - 2
11-27680028-TCC-ACA c.82_84delinsTGT p.G28C Missense 2/2 - 1
11-27680037-GTT-TTG c.73_75delinsCAA p.N25Q Missense 2/2 - 1
11-27680041-GC-TA c.70_71delinsTA p.A24* Nonsense 2/2 - 1
11-27680045-C-T c.67G>A p.E23K Missense 2/2 - 1
11-27680046-TTT-AAA c.64_66inv p.K22F Missense 2/2 - 1
11-27680056-G-A c.56C>T p.A19V Missense 2/2 - 1
11-27680056-G-C c.56C>G p.A19G Missense 2/2 - 1
11-27680056-GC-AA c.55_56delinsTT p.A19F Missense 2/2 - 1
11-27680056-GC-CA c.55_56delinsTG p.A19C Missense 2/2 - 2
11-27680059-GC-AA c.52_53delinsTT p.A18F Missense 2/2 - 1
11-27680061-CTT-AAA c.49_51delinsTTT p.K17F Missense 2/2 - 1
11-27680064-C-T c.48G>A p.M16I Missense 2/2 - 1
11-27680066-T-C c.46A>G p.M16V Missense 2/2 - 1
11-27680068-CA-TC c.43_44delinsGA p.C15D Missense 2/2 - 1
11-27680068-CA-TG c.43_44inv p.C15H Missense 2/2 - 1
11-27680074-AA-GC c.37_38delinsGC p.F13A Missense 2/2 - 1
11-27680074-AA-TC c.37_38delinsGA p.F13D Missense 2/2 - 1
11-27680075-A-T c.37T>A p.F13I Missense 2/2 - 1
11-27680079-TG-AA c.32_33delinsTT p.S11F Missense 2/2 - 1
11-27680079-TGA-ATG c.31_33delinsCAT p.S11H Missense 2/2 - 2
11-27680079-TG-AC c.32_33delinsGT p.S11C Missense 2/2 - 8
11-27680079-TGA-GTC c.31_33delinsGAC p.S11D Missense 2/2 - 6
11-27680080-GA-AT c.31_32delinsAT p.S11I Missense 2/2 - 1
11-27680080-GA-CC c.31_32delinsGG p.S11G Missense 2/2 - 2
11-27680080-GA-TC c.31_32inv p.S11E Missense 2/2 - 3
11-27680080-GA-TT c.31_32delinsAA p.S11K Missense 2/2 - 1
11-27680081-A-C c.31T>G p.S11A Missense 2/2 - 31
11-27680083-A-C c.29T>G p.I10S Missense 2/2 - 1
11-27680091-A-C c.21T>G p.T7= Synonymous 2/2 - 2
11-27680091-A-G c.21T>C p.T7= Synonymous 2/2 - 2
11-27680091-A-T c.21T>A p.T7= Synonymous 2/2 - 2
11-27680094-A-C c.18T>G p.L6= Synonymous 2/2 - 5
11-27680094-A-G c.18T>C p.L6= Synonymous 2/2 - 5
11-27680094-A-T c.18T>A p.L6= Synonymous 2/2 - 5
11-27680106-G-A c.6C>T p.T2= Synonymous 2/2 - 6
11-27680106-G-C c.6C>G p.T2= Synonymous 2/2 - 6
11-27680106-G-T c.6C>A p.T2= Synonymous 2/2 - 6
11-27680107-G-A c.5C>T p.T2I Missense 2/2 - 3
11-27680744-A-T c.-21-612T>A - IntronicSNV - 1/1 34
11-27719559-A-C c.-22+2152T>G - intron_variant - 1/1 2
11-27720937-C-A c.-22+774G>T - intron_variant - 1/1 6
11-27720937-C-G c.-22+774G>C - intron_variant - 1/1 6
11-27720937-C-T c.-22+774G>A - intron_variant - 1/1 6
11-27720983-C-T c.-22+728G>A - intron_variant - 1/1 1
11-27721735-G-A c.-46C>T - 5_prime_UTR_variant 1/2 - 19