PMID: 24225950

Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor.

The Journal of biological chemistry

Zhang, Yingnan Y, Eigenbrot, Charles C, Zhou, Lijuan L, Shia, Steven S, Li, Wei W, Quan, Clifford C, Tom, Jeffrey J, Moran, Paul P, Di Lello, Paola P, Skelton, Nicholas J NJ, Kong-Beltran, Monica M, Peterson, Andrew A, Kirchhofer, Daniel D

2014-01-10

12 variants were identified in this publication

Variant ID	Gene	cDNA	Protein	Consequence	Exon	Intron
1-55523142-TT-GC	PCSK9	c.1135_1136delTTinsGC	p.F379A	Missense	7/12	-
1-55523146-T-C	PCSK9	c.1139T>C	p.V380A	Missense	7/12	-
1-55523107-A-C	PCSK9	c.1100A>C	p.D367A	Missense	7/12	-
1-55523112-AT-GC	PCSK9	c.1105_1106delATinsGC	p.I369A	Missense	7/12	-
1-55512253-AG-GC	PCSK9	c.457_458delAGinsGC	p.S153A	Missense	3/12	-
1-55512259-C-G	PCSK9	c.463C>G	p.P155A	Missense	3/12	-
1-55523128-A-C	PCSK9	c.1121A>C	p.D374A	Missense	7/12	-
1-55518378-A-C	PCSK9	c.713A>C	p.D238A	Missense	5/12	-
1-55518007-CG-GC	PCSK9	c.580_581delCGinsGC	p.R194A	Missense	4/12	-
1-55523151-CA-GC	PCSK9	c.1144_1145delCAinsGC	p.Q382A	Missense	7/12	-
1-55523148-T-G	PCSK9	c.1141T>G	p.S381A	Missense	7/12	-
1-55512268-CT-GC	PCSK9	c.472_473delCTinsGC	p.L158A	Missense	3/12	-