PMID: 27060149

VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research.

Nucleic acids research
Lai, Zhongwu Z, Markovets, Aleksandra A, Ahdesmaki, Miika M, Chapman, Brad B, Hofmann, Oliver O, McEwen, Robert R, Johnson, Justin J, Dougherty, Brian B, Barrett, J Carl JC, Dry, Jonathan R JR
2016-06-20

3779 variants were identified in this publication


Variant ID Gene cDNA Protein Consequence Exon Intron
22-29130456-G-A CHEK2 c.254C>T p.P85L Missense 2/15 -
19-45923619-A-T ERCC1 c.388T>A p.Y130N Missense 4/10 -
11-108186610-G-A ATM c.6067G>A p.G2023R Missense 41/63 -
17-41245027-G-A BRCA1 c.2521C>T p.R841W Missense 10/23 -
7-55259524-T-C EGFR c.2582T>C p.L861P Missense 21/28 -
17-7578212-G-C TP53 c.637C>G p.R213G Missense 6/11 -
13-32968861-T-C BRCA2 c.9292T>C p.Y3098H Missense 25/27 -
17-41246061-C-T BRCA1 c.1487G>A p.R496H Missense 10/23 -
9-21971108-C-T CDKN2A c.250G>A p.D84N Missense 2/3 -
9-21971199-C-G CDKN2A c.159G>C p.M53I Missense 2/3 -
9-21971199-C-T CDKN2A c.159G>A p.M53I Missense 2/3 -
9-21971191-C-A CDKN2A c.167G>T p.S56I Missense 2/3 -
7-55242469-TTAAGAGAAG-C EGFR c.2239_2248delinsC p.L747_A750delinsP MultiAAMissense 19/28 -
5-112170753-G-T APC c.1849G>T p.V617F Missense 15/16 -
3-178916648-G-C PIK3CA c.35G>C p.G12A Missense 2/21 -
19-1220640-C-T STK11 c.658C>T p.Q220* Nonsense 5/10 -
7-55241679-AAAC-A EGFR c.2127_2129delAAC p.E709_T710delinsD MultiAAMissense 18/28 -
8-133894770-C-T TG c.802C>T p.P268S Missense 7/48 -
7-55242469-TTAAGAGAAGCAA-C EGFR c.2239_2251delinsC p.L747_T751delinsP MultiAAMissense 19/28 -
7-55242482-CATCTCCGAAAGCCAACAAGGAAAT-A EGFR c.2252_2276delinsA p.T751_I759delinsN MultiAAMissense 19/28 -
19-1220629-C-T STK11 c.647C>T p.S216F Missense 5/10 -
17-7577523-G-A TP53 c.758C>T p.T253I Missense 7/11 -
7-55259485-C-A EGFR c.2543C>A p.P848Q Missense 21/28 -
2-47630468-C-G MSH2 c.138C>G p.H46Q Missense 1/16 -
22-29091782-G-A CHEK2 c.1175C>T p.A392V Missense 11/15 -
17-7578507-G-T TP53 c.423C>A p.C141* Nonsense 5/11 -
9-5073770-G-A JAK2 c.1849G>A p.V617I Missense 14/25 -
4-1806131-T-C FGFR3 c.1150T>C p.F384L Missense 9/18 -
7-116411923-C-T MET c.2908C>T p.R970C Missense 14/21 -
5-112174677-T-C APC c.3386T>C p.L1129S Missense 16/16 -
17-41215947-C-A BRCA1 c.5096G>T p.R1699L Missense 17/23 -
17-7579344-G-T TP53 c.343C>A p.H115N Missense 4/11 -
2-47637301-T-G MSH2 c.435T>G p.I145M Missense 3/16 -
5-112111326-G-T APC c.423G>T p.R141S Missense 5/16 -
4-1803606-A-C FGFR3 c.784A>C p.N262H Missense 7/18 -
17-7577085-C-A TP53 c.853G>T p.E285* Nonsense 8/11 -
2-48032123-T-TA MSH6 c.3514_3514dup p.R1172Kfs*5 Frameshift 6/10 -
5-137803147-C-T EGR1 c.1009C>T p.P337S Missense 2/2 -
7-81374343-G-A HGF c.719C>T p.P240L Missense 6/18 -
7-81381537-T-C HGF c.524A>G p.N175S Missense 5/18 -
7-81388012-G-T HGF c.363C>A p.N121K Missense 3/18 -
10-8097662-A-C GATA3 c.44A>C p.H15P Missense 2/6 -
11-69631164-A-C FGF3 c.248T>G p.V83G Missense 2/3 -
17-29663445-C-T NF1 c.6101C>T p.T2034I Missense 41/58 -
17-7578427-T-A TP53 c.503A>T p.H168L Missense 5/11 -
5-112175675-AAGAG-A APC c.4391_4394delAGAG p.E1464Vfs*8 Frameshift 16/16 -
4-1806131-T-A FGFR3 c.1150T>A p.F384I Missense 9/18 -
10-8100321-G-T GATA3 c.295G>T p.G99C Missense 3/6 -
10-8100492-A-C GATA3 c.466A>C p.T156P Missense 3/6 -
4-1806182-C-A FGFR3 c.1201C>A p.P401T Missense 9/18 -
17-7577535-C-T TP53 c.746G>A p.R249K Missense 7/11 -
4-1806596-G-A FGFR3 c.1312G>A p.V438M Missense 10/18 -
8-38282064-A-G FGFR1 c.899T>C p.I300T Missense 7/18 -
4-1808964-C-T FGFR3 c.2396C>T p.P799L Missense 18/18 -
7-116339662-G-A MET c.524G>A p.C175Y Missense 2/21 -
7-116340105-A-G MET c.967A>G p.S323G Missense 2/21 -
7-116340214-G-A MET c.1076G>A p.R359Q Missense 2/21 -
7-116340214-G-T MET c.1076G>T p.R359L Missense 2/21 -
7-116380121-G-T MET c.1510G>T p.V504F Missense 4/21 -
7-140476773-C-T BRAF c.1633G>A p.E545K Missense 13/18 -
12-25398284-CC-TT KRAS c.34_35delGGinsAA p.G12N Missense 2/5 -
4-55124970-G-T PDGFRA c.35G>T p.G12V Missense 2/23 -
7-55231427-G-C EGFR c.1633G>C p.E545Q Missense 14/28 -
7-116339691-C-T MET c.553C>T p.L185F Missense 2/21 -
7-116397565-C-A MET c.1937C>A p.T646K Missense 7/21 -
17-7579310-A-T TP53 c.375+2T>A - IntronicSNV - 4/10
7-55259433-C-T EGFR c.2491C>T p.R831C Missense 21/28 -
9-21974775-T-G CDKN2A c.52A>C p.T18P Missense 1/3 -
4-55124969-G-T PDGFRA c.34G>T p.G12C Missense 2/23 -
17-41246566-A-G BRCA1 c.982T>C p.C328R Missense 10/23 -
19-11094894-T-G SMARCA4 c.67T>G p.S23A Missense 2/35 -
11-108123623-C-T ATM c.1882C>T p.Q628* Nonsense 12/63 -
17-41246758-T-G BRCA1 c.790A>C p.S264R Missense 10/23 -
10-43595999-C-A RET c.166C>A p.L56M Missense 2/20 -
19-1220698-G-A STK11 c.716G>A p.W239* Nonsense 5/10 -
11-108098528-T-C ATM c.98T>C p.L33P Missense 3/63 -
15-43773093-C-T TP53BP1 c.499G>A p.D167N Missense 5/28 -
20-31022782-A-C ASXL1 c.2267A>C p.D756A Missense 13/13 -
19-11098473-C-T SMARCA4 c.991C>T p.Q331* Nonsense 6/35 -
7-55249007-G-T EGFR c.2305G>T p.V769L Missense 20/28 -
12-25378567-G-A KRAS c.431C>T p.T144I Missense 4/5 -
7-55259542-A-G EGFR c.2600A>G p.K867R Missense 21/28 -
17-7577129-A-C TP53 c.809T>G p.F270C Missense 8/11 -
7-55242483-CATCTCCGAAAGCCAACAAGGAAAT-C EGFR c.2253_2276del24 p.S752_I759del InFrameDeletion 19/28 -
7-55242467-AATTAAGAGAAGCAACATC-T EGFR c.2237_2255delinsT p.E746_S752delinsV MultiAAMissense 19/28 -
17-7578498-C-A TP53 c.432G>T p.Q144H Missense 5/11 -
5-79950730-AGCG-A MSH3 c.184_186delGCG p.A62del InFrameDeletion 1/24 -
2-29451802-G-C ALK c.2763C>G p.F921L Missense 16/29 -
8-133894202-C-T TG c.733C>T p.L245= Synonymous 6/48 -
19-10610625-C-G KEAP1 c.85G>C p.D29H Missense 2/6 -
17-7577123-A-C TP53 c.815T>G p.V272G Missense 8/11 -
19-10600447-G-T KEAP1 c.1408C>A p.R470S Missense 4/6 -
19-10602340-C-A KEAP1 c.1238G>T p.R413L Missense 3/6 -
7-148513776-C-T EZH2 c.1505G>A p.R502Q Missense 12/20 -
22-29121087-A-C CHEK2 c.470T>G p.I157S Missense 4/15 -
16-2127723-C-T TSC2 c.2962C>T p.R988C Missense 26/42 -
12-25398280-G-T KRAS c.39C>A p.G13= Synonymous 2/5 -
17-7573965-C-A TP53 c.1062G>T p.Q354H Missense 10/11 -
10-89720709-C-A PTEN c.860C>A p.S287* Nonsense 8/9 -
7-55220280-C-T EGFR c.670C>T p.R224C Missense 6/28 -
13-28602329-G-A FLT3 c.2039C>T p.A680V Missense 16/24 -
3-185190873-G-A MAP3K13 c.1754G>A p.R585Q Missense 11/14 -
11-533874-T-G HRAS c.182A>C p.Q61P Missense 3/6 -
17-41256884-C-A BRCA1 c.301+1G>T - IntronicSNV - 5/22
17-37882824-T-C ERBB2 c.2882T>C p.I961T Missense 24/27 -
19-1220717-G-T STK11 c.734+1G>T - IntronicSNV - 5/9
17-29508805-T-G NF1 c.730+2T>G - IntronicSNV - 7/57
11-108117855-G-C ATM c.1065+1G>C - IntronicSNV - 8/62
17-7578505-G-A TP53 c.425C>T p.P142L Missense 5/11 -
12-46244361-C-T ARID2 c.2455C>T p.Q819* Nonsense 15/21 -
1-27023696-C-T ARID1A c.802C>T p.Q268* Nonsense 1/20 -
1-27058031-C-T ARID1A c.1739C>T p.P580L Missense 3/20 -
X-70357654-T-C MED12 c.5905T>C p.S1969P Missense 41/45 -
11-108199845-C-G ATM c.7187C>G p.T2396S Missense 49/63 -
13-32906502-A-G BRCA2 c.887A>G p.Y296C Missense 10/27 -
8-48826575-C-A PRKDC c.2667G>T p.E889D Missense 24/87 -
12-56491703-G-T ERBB3 c.2595G>T p.Q865H Missense 21/28 -
17-7577036-G-T TP53 c.902C>A p.P301Q Missense 8/11 -
17-7578179-C-A TP53 c.670G>T p.E224* Nonsense 6/11 -
17-7579473-G-C TP53 c.214C>G p.P72A Missense 4/11 -
10-8115980-G-T GATA3 c.1329G>T p.M443I Missense 6/6 -
1-27057727-C-T ARID1A c.1435C>T p.Q479* Nonsense 3/20 -
X-76875916-G-T ATRX c.5219C>A p.S1740* Nonsense 20/35 -
17-7573991-C-A TP53 c.1036G>T p.E346* Nonsense 10/11 -
7-140453155-C-G BRAF c.1780G>C p.D594H Missense 15/18 -
7-140453193-T-G BRAF c.1742A>C p.N581T Missense 15/18 -
9-21971111-G-C CDKN2A c.247C>G p.H83D Missense 2/3 -
19-10610279-G-A KEAP1 c.431C>T p.S144F Missense 2/6 -
19-10600510-C-A KEAP1 c.1345G>T p.E449* Nonsense 4/6 -
7-81346567-A-T HGF c.1386T>A p.D462E Missense 11/18 -
17-7579521-C-A TP53 c.166G>T p.E56* Nonsense 4/11 -
2-178098809-T-A NFE2L2 c.236A>T p.E79V Missense 2/5 -
4-55561716-C-A KIT c.106C>A p.P36T Missense 2/21 -
19-11144113-G-A SMARCA4 c.3694G>A p.G1232S Missense 26/35 -
17-7576853-C-A TP53 c.993G>T p.Q331H Missense 9/11 -
17-7578499-T-A TP53 c.431A>T p.Q144L Missense 5/11 -
17-7577573-G-T TP53 c.708C>A p.Y236* Nonsense 7/11 -
17-7578264-G-C TP53 c.585C>G p.I195M Missense 6/11 -
17-7578508-C-A TP53 c.422G>T p.C141F Missense 5/11 -
17-7577130-A-C TP53 c.808T>G p.F270V Missense 8/11 -
8-128750604-CCAG-C MYC c.154_156delCAG p.Q52del InFrameDeletion 2/3 -
9-135771987-CGCT-C TSC1 c.3127_3129delAGC p.S1043del InFrameDeletion 23/23 -
22-41489087-G-A EP300 c.79G>A p.A27T Missense 1/31 -
2-190742066-C-G PMS1 c.2703C>G p.I901M Missense 13/13 -
19-1220502-G-T STK11 c.595G>T p.E199* Nonsense 4/10 -
11-108216546-G-A ATM c.8495G>A p.R2832H Missense 58/63 -
3-12645699-G-C RAF1 c.770C>G p.S257W Missense 7/17 -
10-89690805-G-A PTEN c.212G>A p.C71Y Missense 4/9 -
13-32911471-G-T BRCA2 c.2979G>T p.W993C Missense 11/27 -
19-10597342-TCTG-T KEAP1 c.1858_1860delCAG p.Q620del InFrameDeletion 6/6 -
22-50356707-G-A PIM3 c.913G>A p.D305N Missense 6/6 -
X-66765158-T-A AR c.170T>A p.L57Q Missense 1/8 -
16-23635370-C-T PALB2 c.2794G>A p.V932M Missense 8/13 -
2-29448423-T-G ALK c.3076A>C p.T1026P Missense 19/29 -
5-112178112-C-T APC c.6821C>T p.A2274V Missense 16/16 -
22-41546158-C-A EP300 c.2773C>A p.P925T Missense 14/31 -
17-7578202-A-G TP53 c.647T>C p.V216A Missense 6/11 -
17-41226380-G-A BRCA1 c.4643C>T p.T1548M Missense 14/23 -
5-137801662-G-A EGR1 c.212G>A p.G71E Missense 1/2 -
19-10602329-C-T KEAP1 c.1249G>A p.G417R Missense 3/6 -
16-68855966-G-A CDH1 c.1774G>A p.A592T Missense 12/16 -
22-29115467-A-G CHEK2 c.599T>C p.V200A Missense 5/15 -
17-37881377-A-C ERBB2 c.2569A>C p.N857H Missense 21/27 -
17-1792132-G-A RPA1 c.1538G>A p.R513H Missense 14/17 -
17-7572980-T-G TP53 c.1129A>C p.T377P Missense 11/11 -
17-63526198-C-T AXIN2 c.2428G>A p.D810N Missense 11/11 -
9-5126715-A-G JAK2 c.3323A>G p.N1108S Missense 25/25 -
17-29560127-G-T NF1 c.3604G>T p.A1202S Missense 27/58 -
2-29519818-C-T ALK c.1753G>A p.A585T Missense 9/29 -
17-29557906-A-C NF1 c.3160A>C p.N1054H Missense 24/58 -
17-29496957-T-A NF1 c.528T>A p.D176E Missense 5/58 -
17-29588803-A-G NF1 c.4652A>G p.H1551R Missense 35/58 -
17-29653127-A-G NF1 c.5125A>G p.I1709V Missense 37/58 -
17-7579480-A-C TP53 c.207T>G p.A69= Synonymous 4/11 -
17-29497010-T-G NF1 c.581T>G p.L194R Missense 5/58 -
13-25044054-T-C PARP4 c.2024A>G p.N675S Missense 16/34 -
17-29509529-G-T NF1 c.734G>T p.C245F Missense 8/58 -
17-29554278-G-T NF1 c.2294G>T p.R765L Missense 19/58 -
17-29553658-A-G NF1 c.2207A>G p.N736S Missense 18/58 -
17-29684094-C-T NF1 c.7855C>T p.L2619F Missense 53/58 -
17-29686013-T-G NF1 c.8140T>G p.F2714V Missense 56/58 -
2-212537974-C-A ERBB4 c.1631G>T p.R544L Missense 14/28 -
17-29701143-C-A NF1 c.8490C>A p.F2830L Missense 58/58 -
19-1220410-A-G STK11 c.503A>G p.H168R Missense 4/10 -
13-32907236-G-A BRCA2 c.1621G>A p.E541K Missense 10/27 -
2-47710077-G-A MSH2 c.2794G>A p.V932I Missense 16/16 -
7-55242491-A-T EGFR c.2261A>T p.K754I Missense 19/28 -
7-55242490-A-G EGFR c.2260A>G p.K754E Missense 19/28 -
X-76938787-C-T ATRX c.1961G>A p.R654Q Missense 9/35 -
4-55976691-T-A KDR c.1134A>T p.K378N Missense 9/30 -
17-7579485-C-A TP53 c.202G>T p.E68* Nonsense 4/11 -
13-32937423-C-A BRCA2 c.8084C>A p.S2695* Nonsense 18/27 -
7-140624425-C-T BRAF c.79G>A p.A27T Missense 1/18 -
3-41266124-A-C CTNNB1 c.121A>C p.T41P Missense 3/15 -
3-41266124-A-T CTNNB1 c.121A>T p.T41S Missense 3/15 -
17-37880997-G-GTGT ERBB2 c.2326_2327insTGT p.G776delinsVC MultiAAMissense 20/27 -
17-37880997-G-GTTT ERBB2 c.2326_2327insTTT p.G776delinsVC MultiAAMissense 20/27 -
22-24176339-G-A SMARCB1 c.1130G>A p.R377H Missense 9/9 -
20-62839407-AGAG-A MYT1 c.870_872delGGA p.E306del InFrameDeletion 7/23 -
17-7573991-C-T TP53 c.1036G>A p.E346K Missense 10/11 -
17-29490279-C-T NF1 c.364C>T p.H122Y Missense 4/58 -
17-29527600-T-G NF1 c.1049T>G p.V350G Missense 9/58 -
10-30748222-T-A MAP3K8 c.1065T>A p.D355E Missense 8/9 -
17-41246737-C-T BRCA1 c.811G>A p.V271M Missense 10/23 -
22-29083962-G-A CHEK2 c.1555C>T p.R519* Nonsense 15/15 -
13-32900251-C-T BRCA2 c.439C>T p.Q147* Nonsense 5/27 -
2-48028084-C-T MSH6 c.2962C>T p.R988C Missense 4/10 -
17-37619304-A-G CDK12 c.980A>G p.Y327C Missense 1/14 -
20-57484421-G-T GNAS c.602G>T p.R201L Missense 8/13 -
8-90982772-C-T NBN c.716G>A p.S239N Missense 7/16 -
19-11105642-G-T SMARCA4 c.1558G>T p.E520* Nonsense 9/35 -
16-23641233-T-C PALB2 c.2242A>G p.T748A Missense 5/13 -
22-41522001-C-T EP300 c.863C>T p.A288V Missense 3/31 -
2-212537975-G-A ERBB4 c.1630C>T p.R544W Missense 14/28 -
17-41246294-C-A BRCA1 c.1254G>T p.E418D Missense 10/23 -
19-1226491-C-T STK11 c.1147C>T p.R383C Missense 9/10 -
19-1220699-G-T STK11 c.717G>T p.W239C Missense 5/10 -
8-133883681-G-A TG c.363G>A p.Q121= Synonymous 4/48 -
12-25398220-A-T KRAS c.99T>A p.D33E Missense 2/5 -
13-32905148-A-T BRCA2 c.774A>T p.Q258H Missense 9/27 -
13-32906426-G-A BRCA2 c.811G>A p.G271R Missense 10/27 -
13-32914044-T-G BRCA2 c.5552T>G p.I1851S Missense 11/27 -
17-59938833-G-A BRIP1 c.68C>T p.P23L Missense 2/20 -
19-52709293-C-T PPP2R1A c.247C>T p.P83S Missense 3/15 -
3-37092125-A-G MLH1 c.2252A>G p.K751R Missense 19/19 -
2-47690245-T-G MSH2 c.1462T>G p.L488V Missense 9/16 -
10-89711876-G-T PTEN c.494G>T p.G165V Missense 6/9 -
17-41276064-G-C BRCA1 c.50C>G p.A17G Missense 2/23 -
17-41267787-C-A BRCA1 c.90G>T p.L30F Missense 3/23 -
7-55242479-CAACATCTCCGAAAGCCAACAAGGA-C EGFR c.2252_2275del24 p.T751_E758del InFrameDeletion 19/28 -
17-41258545-C-T BRCA1 c.140G>A p.C47Y Missense 4/23 -
1-46725698-C-G RAD54L c.334C>G p.P112A Missense 5/18 -
17-41243809-C-T BRCA1 c.3739G>A p.V1247I Missense 10/23 -
17-41245026-C-T BRCA1 c.2522G>A p.R841Q Missense 10/23 -
13-32913947-C-T BRCA2 c.5455C>T p.P1819S Missense 11/27 -
13-32971125-T-C BRCA2 c.9592T>C p.C3198R Missense 26/27 -
2-48033775-C-T MSH6 c.3986C>T p.S1329L Missense 9/10 -
4-72631259-G-T GC c.363C>A p.L121= Synonymous 4/13 -
9-5072561-G-A JAK2 c.1711G>A p.G571S Missense 13/25 -
19-10602822-C-A KEAP1 c.756G>T p.W252C Missense 3/6 -
4-72635070-C-A GC c.106G>T p.G36* Nonsense 2/13 -
19-17949092-G-A JAK3 c.1549C>T p.P517S Missense 11/24 -
17-41258494-C-A BRCA1 c.191G>T p.C64F Missense 4/23 -
17-41256953-C-A BRCA1 c.233G>T p.R78I Missense 5/23 -
17-41258478-G-T BRCA1 c.207C>A p.T69= Synonymous 4/23 -
17-41256924-T-A BRCA1 c.262A>T p.K88* Nonsense 5/23 -
17-41256906-G-C BRCA1 c.280C>G p.Q94E Missense 5/23 -
17-41223010-C-G BRCA1 c.4921G>C p.A1641P Missense 15/23 -
17-41215947-C-G BRCA1 c.5096G>C p.R1699P Missense 17/23 -
8-133906122-G-C TG c.2949G>C p.A983= Synonymous 11/48 -
19-10602620-G-A KEAP1 c.958C>T p.R320W Missense 3/6 -
6-35423840-G-A FANCE c.565G>A p.E189K Missense 2/10 -
7-116397705-C-G MET c.1979C>G p.T660R Missense 8/21 -
8-133899241-G-A TG c.1624G>A p.G542S Missense 9/48 -
12-25398284-CC-TA KRAS c.34_35delGGinsTA p.G12Y Missense 2/5 -
7-55225444-A-T EGFR c.1296A>T p.Q432H Missense 11/28 -
7-55266427-T-A EGFR c.2719T>A p.L907M Missense 23/28 -
X-14863236-C-G FANCB c.1669G>C p.D557H Missense 8/10 -
17-78897403-G-T RPTOR c.2738G>T p.G913V Missense 23/34 -
19-10602840-G-C KEAP1 c.738C>G p.F246L Missense 3/6 -
9-80537095-G-T GNAQ c.303C>A p.Y101* Nonsense 2/7 -
11-108205768-G-A ATM c.8083G>A p.G2695S Missense 55/63 -
13-48934155-G-T RB1 c.610G>T p.E204* Nonsense 7/27 -
1-11300539-T-G MTOR c.1607A>C p.Q536P Missense 11/58 -
X-70345279-C-A MED12 c.2305C>A p.H769N Missense 16/45 -
8-6302154-G-T MCPH1 c.911G>T p.R304I Missense 8/14 -
12-133237666-C-G POLE c.2949G>C p.K983N Missense 25/49 -
17-7579533-G-A TP53 c.154C>T p.Q52* Nonsense 4/11 -
X-66765161-A-T AR c.173A>T p.Q58L Missense 1/8 -
11-108218090-T-G ATM c.8669T>G p.L2890R Missense 59/63 -
12-133220441-C-A POLE c.4272G>T p.E1424D Missense 33/49 -
13-113897418-A-G CUL4A c.1172A>G p.K391R Missense 11/20 -
2-48027856-T-C MSH6 c.2734T>C p.W912R Missense 4/10 -
19-10600477-T-C KEAP1 c.1378A>G p.R460G Missense 4/6 -
19-17949121-T-C JAK3 c.1520A>G p.Q507R Missense 11/24 -
17-29653005-G-T NF1 c.5003G>T p.G1668V Missense 37/58 -
7-55242463-A-G EGFR c.2233A>G p.K745E Missense 19/28 -
7-81335640-G-T HGF c.1720C>A p.P574T Missense 15/18 -
5-112116562-C-G APC c.607C>G p.Q203E Missense 6/16 -
2-212578346-C-A ERBB4 c.911G>T p.C304F Missense 8/28 -
X-76875878-T-C ATRX c.5257A>G p.N1753D Missense 20/35 -
8-90976659-G-A NBN c.973C>T p.P325S Missense 8/16 -
15-89805064-G-T FANCI c.458G>T p.G153V Missense 6/38 -
10-43602005-C-A RET c.1049C>A p.T350N Missense 5/20 -
17-7579433-G-A TP53 c.254C>T p.P85L Missense 4/11 -
2-190738243-A-T PMS1 c.2495A>T p.Y832F Missense 12/13 -
17-7577521-T-A TP53 c.760A>T p.I254F Missense 7/11 -
7-81346644-C-G HGF c.1309G>C p.E437Q Missense 11/18 -
18-39537617-C-G PIK3C3 c.151C>G p.Q51E Missense 2/25 -
1-226549183-T-C PARP1 c.3023A>G p.N1008S Missense 23/23 -
3-142232433-C-T ATR c.4551G>A p.M1517I Missense 26/47 -
16-23634330-C-A PALB2 c.2956G>T p.D986Y Missense 9/13 -
16-68849475-G-T CDH1 c.1378G>T p.V460L Missense 10/16 -
19-52719903-A-T PPP2R1A c.1115A>T p.Q372L Missense 9/15 -
3-30713794-G-A TGFBR2 c.1119G>A p.M373I Missense 4/7 -
2-29416528-G-T ALK c.4425C>A p.H1475Q Missense 29/29 -
12-46215209-G-T ARID2 c.644G>T p.G215V Missense 6/21 -
4-55971037-C-A KDR c.1760G>T p.G587V Missense 13/30 -
19-11136141-T-C SMARCA4 c.3125T>C p.L1042P Missense 22/35 -
1-11264722-C-A MTOR c.3840G>T p.W1280C Missense 26/58 -
1-243809209-G-A AKT3 c.415C>T p.H139Y Missense 5/14 -
19-1220448-A-T STK11 c.541A>T p.N181Y Missense 4/10 -
1-27097658-G-T ARID1A c.3247G>T p.G1083C Missense 12/20 -
12-133219516-T-G POLE c.4618A>C p.K1540Q Missense 36/49 -
19-11141507-G-T SMARCA4 c.3484G>T p.G1162C Missense 25/35 -
19-1220706-G-T STK11 c.724G>T p.G242W Missense 5/10 -
7-81372711-C-A HGF c.823G>T p.D275Y Missense 7/18 -
19-11135100-G-C SMARCA4 c.3067G>C p.E1023Q Missense 21/35 -
11-108205768-G-T ATM c.8083G>T p.G2695C Missense 55/63 -
1-27092806-C-A ARID1A c.2827C>A p.P943T Missense 9/20 -
20-31022625-G-A ASXL1 c.2110G>A p.G704R Missense 13/13 -
5-170834751-G-C NPM1 c.819G>C p.K273N Missense 10/11 -
3-10136010-G-T FANCD2 c.3926G>T p.C1309F Missense 40/44 -
17-37873642-G-T ERBB2 c.1807G>T p.G603C Missense 15/27 -
22-29083962-G-C CHEK2 c.1555C>G p.R519G Missense 15/15 -
9-5044417-G-T JAK2 c.365G>T p.R122L Missense 5/25 -
11-108236220-G-C ATM c.9156G>C p.W3052C Missense 63/63 -
17-29667604-A-C NF1 c.7003A>C p.T2335P Missense 47/58 -
19-10602328-C-T KEAP1 c.1250G>A p.G417E Missense 3/6 -
11-69456155-A-C CCND1 c.74A>C p.D25A Missense 1/5 -
2-42511835-G-C EML4 c.1003G>C p.D335H Missense 9/23 -
20-30309796-C-G BCL2L1 c.226G>C p.D76H Missense 2/3 -
19-45860756-G-T ERCC2 c.1353C>A p.F451L Missense 14/23 -
X-115304135-C-T AGTR2 c.602C>T p.P201L Missense 3/3 -
19-30313407-T-C CCNE1 c.1007T>C p.M336T Missense 11/12 -
19-10610405-G-A KEAP1 c.305C>T p.S102L Missense 2/6 -
2-209113181-C-T IDH1 c.326G>A p.R109K Missense 4/10 -
19-10602925-T-A KEAP1 c.653A>T p.E218V Missense 3/6 -
5-112175531-G-A APC c.4240G>A p.V1414I Missense 16/16 -
13-32907276-G-T BRCA2 c.1661G>T p.C554F Missense 10/27 -
19-10602335-G-A KEAP1 c.1243C>T p.R415C Missense 3/6 -
7-81392114-G-T HGF c.163C>A p.P55T Missense 2/18 -
4-55140718-G-T PDGFRA c.1579G>T p.V527L Missense 11/23 -
19-10600365-C-A KEAP1 c.1490G>T p.W497L Missense 4/6 -
1-65300289-T-A JAK1 c.3421A>T p.S1141C Missense 25/25 -
2-30142880-G-C ALK c.646C>G p.L216V Missense 1/29 -
2-215645996-C-G BARD1 c.602G>C p.R201T Missense 4/11 -
3-142224081-T-G ATR c.5096A>C p.E1699A Missense 29/47 -
19-10602739-A-T KEAP1 c.839T>A p.F280Y Missense 3/6 -
8-48817449-C-A PRKDC c.3022G>T p.A1008S Missense 26/87 -
12-133256567-C-A POLE c.396G>T p.E132D Missense 5/49 -
19-1207079-G-T STK11 c.167G>T p.G56V Missense 1/10 -
19-1207144-A-G STK11 c.232A>G p.K78E Missense 1/10 -
7-6018269-T-C PMS2 c.2233A>G p.I745V Missense 13/15 -
1-46726628-G-C RAD54L c.707G>C p.G236A Missense 7/18 -
5-80109418-G-T MSH3 c.2671G>T p.V891L Missense 20/24 -
12-25378676-C-A KRAS c.322G>T p.D108Y Missense 4/5 -
8-90965679-T-A NBN c.1638A>T p.R546S Missense 11/16 -
12-25380319-C-A KRAS c.139G>T p.D47Y Missense 3/5 -
4-55594049-T-C KIT c.1835T>C p.I612T Missense 12/21 -
2-212522507-C-A ERBB4 c.1918G>T p.G640C Missense 16/28 -
4-55946163-G-T KDR c.4016C>A p.T1339K Missense 30/30 -
17-7578398-G-A TP53 c.532C>T p.H178Y Missense 5/11 -
8-133885355-G-A TG c.527G>A p.G176E Missense 5/48 -
8-133885355-G-T TG c.527G>T p.G176V Missense 5/48 -
17-7577508-TC-T TP53 c.772delG p.E258Kfs*87 Frameshift 7/11 -
17-7579365-C-G TP53 c.322G>C p.G108R Missense 4/11 -
19-45856059-C-G ERCC2 c.1847G>C p.R616P Missense 20/23 -
19-45856059-C-T ERCC2 c.1847G>A p.R616Q Missense 20/23 -
17-7578397-TG-T TP53 c.532delC p.H178Tfs*69 Frameshift 5/11 -
X-115303595-G-T AGTR2 c.62G>T p.G21V Missense 3/3 -
7-55242427-C-A EGFR c.2197C>A p.P733T Missense 19/28 -
17-7578466-G-A TP53 c.464C>T p.T155I Missense 5/11 -
11-94212892-T-C MRE11 c.350A>G p.N117S Missense 5/20 -
17-7577578-T-C TP53 c.703A>G p.N235D Missense 7/11 -
17-7577112-C-A TP53 c.826G>T p.A276S Missense 8/11 -
17-78519464-G-T RPTOR c.35G>T p.G12V Missense 1/34 -
7-55268882-G-T EGFR c.2948G>T p.G983V Missense 25/28 -
17-7578199-A-C TP53 c.650T>G p.V217G Missense 6/11 -
20-31024698-C-G ASXL1 c.4183C>G p.L1395V Missense 13/13 -
4-55124970-G-A PDGFRA c.35G>A p.G12D Missense 2/23 -
8-133894142-C-T TG c.673C>T p.Q225* Nonsense 6/48 -
3-41266166-G-A CTNNB1 c.163G>A p.E55K Missense 3/15 -
19-1222987-G-T STK11 c.924G>T p.W308C Missense 8/10 -
15-99467189-A-C IGF1R c.2570A>C p.N857T Missense 12/21 -
7-140501254-C-A BRAF c.818G>T p.S273I Missense 6/18 -
12-25380253-C-A KRAS c.205G>T p.D69Y Missense 3/5 -
11-108106508-A-C ATM c.443A>C p.D148A Missense 5/63 -
16-2138570-C-T TSC2 c.5383C>T p.R1795C Missense 42/42 -
2-39262581-C-A SOS1 c.925G>T p.D309Y Missense 7/23 -
11-533557-T-G HRAS c.346A>C p.N116H Missense 4/6 -
7-55242502-GGAA-G EGFR c.2272_2274delGAA p.E758del InFrameDeletion 19/28 -
5-112174682-C-T APC c.3391C>T p.Q1131* Nonsense 16/16 -
12-25378648-T-C KRAS c.350A>G p.K117R Missense 4/5 -
16-23646673-C-T PALB2 c.1194G>A p.V398= Synonymous 4/13 -
7-55242457-G-A EGFR c.2227G>A p.A743T Missense 19/28 -
11-94192599-G-T MRE11 c.1475C>A p.A492D Missense 13/20 -
7-6045549-C-T PMS2 c.137G>A p.S46N Missense 2/15 -
22-29130456-G-C CHEK2 c.254C>G p.P85R Missense 2/15 -
12-133256096-C-T POLE c.565G>A p.A189T Missense 6/49 -
16-23634324-G-A PALB2 c.2962C>T p.Q988* Nonsense 9/13 -
17-7579338-C-A TP53 c.349G>T p.G117W Missense 4/11 -
17-7577589-G-A TP53 c.692C>T p.T231I Missense 7/11 -
19-11097098-C-T SMARCA4 c.589C>T p.P197S Missense 4/35 -
3-52651527-C-A PBRM1 c.1569G>T p.M523I Missense 15/30 -
10-43610046-G-T RET c.1998G>T p.K666N Missense 11/20 -
4-1806137-T-C FGFR3 c.1156T>C p.F386L Missense 9/18 -
1-45798835-G-T MUTYH c.312C>A p.V104= Synonymous 5/16 -
15-90631923-C-G IDH2 c.430G>C p.G144R Missense 4/11 -
13-49030468-C-G RB1 c.1943C>G p.S648* Nonsense 19/27 -
1-27106648-G-A ARID1A c.6259G>A p.G2087R Missense 20/20 -
1-162745624-G-T DDR2 c.2039G>T p.R680L Missense 15/18 -
8-133898695-G-T TG c.1078G>T p.E360* Nonsense 9/48 -
9-5126726-C-T JAK2 c.3334C>T p.Q1112* Nonsense 25/25 -
9-135779052-G-A TSC1 c.2194C>T p.H732Y Missense 17/23 -
12-58145463-C-T CDK4 c.38G>A p.G13D Missense 2/8 -
7-55259515-T-A EGFR c.2573T>A p.L858Q Missense 21/28 -
9-135786451-G-T TSC1 c.1079C>A p.T360N Missense 11/23 -
11-108151830-C-T ATM c.3511C>T p.Q1171* Nonsense 24/63 -
13-32911286-G-A BRCA2 c.2794G>A p.D932N Missense 11/27 -
2-47710068-C-T MSH2 c.2785C>T p.R929* Nonsense 16/16 -
3-38182040-A-C MYD88 c.625A>C p.S209R Missense 3/5 -
7-55259441-G-T EGFR c.2499G>T p.L833F Missense 21/28 -
20-31022839-T-G ASXL1 c.2324T>G p.L775* Nonsense 13/13 -
17-29664869-G-A NF1 c.6675G>A p.W2225* Nonsense 44/58 -
11-108098386-G-T ATM c.35G>T p.C12F Missense 2/63 -
7-81392107-A-T HGF c.170T>A p.L57Q Missense 2/18 -
19-30314634-A-C CCNE1 c.1183A>C p.T395P Missense 12/12 -
11-108150267-C-T ATM c.3334C>T p.P1112S Missense 23/63 -
1-11182094-C-T MTOR c.6752G>A p.R2251Q Missense 48/58 -
1-11182049-C-G MTOR c.6797G>C p.R2266P Missense 48/58 -
5-112128143-C-G APC c.646C>G p.R216G Missense 7/16 -
17-7578513-C-A TP53 c.417G>T p.K139N Missense 5/11 -
17-7579577-G-C TP53 c.110C>G p.S37C Missense 4/11 -
7-55227989-C-T EGFR c.1456C>T p.Q486* Nonsense 12/28 -
3-178937410-G-A PIK3CA c.1798G>A p.E600K Missense 12/21 -
6-152129063-C-T ESR1 c.16C>T p.H6Y Missense 1/8 -
17-7579846-A-C TP53 c.67T>G p.W23G Missense 2/11 -
19-10610361-C-T KEAP1 c.349G>A p.E117K Missense 2/6 -
17-37873715-C-A ERBB2 c.1880C>A p.P627H Missense 15/27 -
13-28602376-C-T FLT3 c.1992G>A p.M664I Missense 16/24 -
16-89882989-C-T FANCA c.35G>A p.G12D Missense 1/43 -
5-112174802-C-T APC c.3511C>T p.R1171C Missense 16/16 -
16-23647569-G-A PALB2 c.298C>T p.L100F Missense 4/13 -
7-6022480-C-T PMS2 c.2149G>A p.V717M Missense 12/15 -
5-79950708-TGCAGCGGCC-T MSH3 c.178_186delGCCGCAGCG p.A60_A62del InFrameDeletion 1/24 -
5-112176020-G-T APC c.4729G>T p.E1577* Nonsense 16/16 -
16-68855966-G-T CDH1 c.1774G>T p.A592S Missense 12/16 -
17-29560134-G-T NF1 c.3611G>T p.R1204L Missense 27/58 -
17-7577599-C-G TP53 c.682G>C p.D228H Missense 7/11 -
X-76931741-GTCA-G ATRX c.3786_3788delTGA p.D1264del InFrameDeletion 10/35 -
13-32910995-C-T BRCA2 c.2503C>T p.P835S Missense 11/27 -
7-116339431-G-T MET c.293G>T p.C98F Missense 2/21 -
7-116340082-A-G MET c.944A>G p.N315S Missense 2/21 -
2-29443600-G-A ALK c.3617C>T p.S1206F Missense 23/29 -
2-29430080-C-A ALK c.3895G>T p.E1299* Nonsense 26/29 -
10-8115710-A-C GATA3 c.1059A>C p.R353S Missense 6/6 -
12-133249767-G-A POLE c.1456C>T p.P486S Missense 14/49 -
4-55131118-C-T PDGFRA c.661C>T p.L221F Missense 5/23 -
11-108206578-G-C ATM c.8158G>C p.D2720H Missense 56/63 -
1-11272478-T-C MTOR c.3452A>G p.Y1151C Missense 23/58 -
17-56774116-T-G RAD51C c.467T>G p.V156G Missense 3/9 -
17-7579475-G-A TP53 c.212C>T p.P71L Missense 4/11 -
7-140434413-G-T BRAF c.2285C>A p.A762E Missense 18/18 -
10-89692830-G-A PTEN c.314G>A p.C105Y Missense 5/9 -
7-55240737-G-T EGFR c.1981G>T p.A661S Missense 17/28 -
19-10602727-T-A KEAP1 c.851A>T p.Q284L Missense 3/6 -
19-11100015-C-T SMARCA4 c.1141C>T p.R381* Nonsense 7/35 -
17-29556431-T-C NF1 c.2798T>C p.L933P Missense 21/58 -
2-215645889-G-C BARD1 c.709C>G p.Q237E Missense 4/11 -
2-215645684-T-G BARD1 c.914A>C p.K305T Missense 4/11 -
2-215674232-C-A BARD1 c.62G>T p.R21L Missense 1/11 -
10-43609930-C-T RET c.1882C>T p.P628S Missense 11/20 -
19-1221948-G-T STK11 c.863G>T p.G288V Missense 7/10 -
12-25362793-T-C KRAS c.503A>G p.E168G Missense 5/5 -
17-41246815-C-A BRCA1 c.733G>T p.D245Y Missense 10/23 -
3-178921404-C-G PIK3CA c.886C>G p.Q296E Missense 5/21 -
22-41574340-AACCAGTTCCAGC-A EP300 c.6627_6638del12 p.N2209_Q2213delinsK MultiAAMissense 31/31 -
7-55268896-C-T EGFR c.2962C>T p.H988Y Missense 25/28 -
17-37881617-G-A ERBB2 c.2687G>A p.R896H Missense 22/27 -
10-43609104-C-A RET c.1860C>A p.C620* Nonsense 10/20 -
17-29527483-G-A NF1 c.932G>A p.G311E Missense 9/58 -
3-37035072-G-T MLH1 c.34G>T p.D12Y Missense 1/19 -
17-7578462-G-T TP53 c.468C>A p.R156= Synonymous 5/11 -
7-140534477-G-A BRAF c.436C>T p.R146W Missense 3/18 -
12-25378602-G-T KRAS c.396C>A p.D132E Missense 4/5 -
4-55130065-C-G PDGFRA c.599C>G p.T200S Missense 4/23 -
3-156422507-C-T TIPARP c.1561C>T p.R521C Missense 6/6 -
16-23649206-GACAA-G PALB2 c.172_175delTTGT p.Q60Rfs*7 Frameshift 3/13 -
19-1221313-G-GC STK11 c.842dupC p.L282Afs*3 Frameshift 6/10 -
11-22646871-CAG-C FANCF c.484_485delCT p.L162Dfs*103 Frameshift 1/1 -
7-6018318-AGT-C PMS2 c.2182_2184delinsG p.T728Afs*7 Frameshift 13/15 -
19-1207090-T-TA STK11 c.179_179dup p.Y60* Nonsense 1/10 -
5-131931451-T-TA RAD50 c.2157_2157dupA p.E723Gfs*5 Frameshift 13/25 -
11-108198404-ATG-A ATM c.7010_7011delGT p.C2337Sfs*35 Frameshift 48/63 -
12-133254220-G-A POLE c.664C>T p.R222C Missense 7/49 -
13-32900287-G-C BRCA2 c.475G>C p.V159L Missense 5/27 -
19-45856038-A-AC ERCC2 c.1867_1867dupG p.V623Gfs*26 Frameshift 20/23 -
12-25378686-CT-C KRAS c.311delA p.K104Rfs*10 Frameshift 4/5 -
17-7576899-G-A TP53 c.947C>T p.P316L Missense 9/11 -
4-55981449-G-T KDR c.488C>A p.A163E Missense 4/30 -
17-7579457-G-A TP53 c.230C>T p.P77L Missense 4/11 -
3-52441235-G-A BAP1 c.535C>T p.R179W Missense 7/17 -
13-49047525-G-T RB1 c.2519G>T p.G840V Missense 24/27 -
2-48032123-T-TAA MSH6 c.3514_3515insAA p.R1172Kfs*13 Frameshift 6/10 -
12-133202283-G-A POLE c.6605C>T p.T2202M Missense 47/49 -
13-32972857-G-C BRCA2 c.10207G>C p.E3403Q Missense 27/27 -
13-22275471-G-A FGF9 c.524G>A p.G175E Missense 3/3 -
12-133209087-G-C POLE c.6144C>G p.I2048M Missense 45/49 -
12-133209279-T-A POLE c.6107A>T p.E2036V Missense 44/49 -
3-185198141-G-A MAP3K13 c.2623G>A p.D875N Missense 13/14 -
15-99500663-A-C IGF1R c.4096A>C p.T1366P Missense 21/21 -
19-1226540-A-C STK11 c.1196A>C p.Q399P Missense 9/10 -
19-1226593-G-A STK11 c.1249G>A p.A417T Missense 9/10 -
17-41243454-A-C BRCA1 c.4094T>G p.L1365* Nonsense 10/23 -
17-7572932-C-T TP53 c.1177G>A p.D393N Missense 11/11 -
17-7572989-C-A TP53 c.1120G>T p.G374C Missense 11/11 -
20-31024450-C-T ASXL1 c.3935C>T p.A1312V Missense 13/13 -
3-41280675-G-A CTNNB1 c.2188G>A p.G730S Missense 15/15 -
2-39213021-G-A SOS1 c.3946C>T p.H1316Y Missense 23/23 -
19-1226527-A-C STK11 c.1183A>C p.T395P Missense 9/10 -
17-41243499-C-G BRCA1 c.4049G>C p.G1350A Missense 10/23 -
17-41243533-C-A BRCA1 c.4015G>T p.E1339* Nonsense 10/23 -
17-7576878-A-G TP53 c.968T>C p.L323P Missense 9/11 -
17-59760881-T-G BRIP1 c.3526A>C p.I1176L Missense 20/20 -
3-185198306-C-T MAP3K13 c.2788C>T p.R930C Missense 13/14 -
3-52588770-C-T PBRM1 c.4258G>A p.V1420M Missense 27/30 -
2-212248650-G-A ERBB4 c.3617C>T p.P1206L Missense 28/28 -
2-212251638-G-A ERBB4 c.3421C>T p.P1141S Missense 27/28 -
4-55161414-A-G PDGFRA c.3245A>G p.D1082G Missense 23/23 -
7-55266471-C-A EGFR c.2763C>A p.S921R Missense 23/28 -
8-90965540-G-A NBN c.1777C>T p.P593S Missense 11/16 -
17-7579398-AC-A TP53 c.289delG p.V97Sfs*26 Frameshift 4/11 -
12-133253208-G-T POLE c.833C>A p.T278K Missense 9/49 -
4-72635086-C-A GC c.90G>T p.K30N Missense 2/13 -
3-12650418-C-A RAF1 c.428G>T p.R143L Missense 5/17 -
1-27106069-C-T ARID1A c.5680C>T p.Q1894* Nonsense 20/20 -
11-108114701-G-A ATM c.518G>A p.R173K Missense 6/63 -
13-32905065-A-C BRCA2 c.691A>C p.S231R Missense 9/27 -
8-38275744-AC-A FGFR1 c.1430+1delG - IntronicDeletion 10/18 -
7-55228029-G-A EGFR c.1496G>A p.C499Y Missense 12/28 -
17-41244664-C-T BRCA1 c.2884G>A p.E962K Missense 10/23 -
3-178938805-A-G PIK3CA c.2047A>G p.R683G Missense 14/21 -
2-29455179-C-T ALK c.2623G>A p.G875R Missense 15/29 -
13-32905094-G-C BRCA2 c.720G>C p.L240= Synonymous 9/27 -
13-32912186-G-A BRCA2 c.3694G>A p.E1232K Missense 11/27 -
17-41245501-T-C BRCA1 c.2047A>G p.K683E Missense 10/23 -
4-55156608-G-T PDGFRA c.3009G>T p.W1003C Missense 22/23 -
12-133254216-T-G POLE c.668A>C p.E223A Missense 7/49 -
17-41246317-C-T BRCA1 c.1231G>A p.D411N Missense 10/23 -
17-29422361-G-T NF1 c.34G>T p.A12S Missense 1/58 -
8-90965536-C-T NBN c.1781G>A p.R594K Missense 11/16 -
8-133880411-C-A TG c.119C>A p.T40K Missense 2/48 -
17-7578244-C-G TP53 c.605G>C p.R202P Missense 6/11 -
7-55240794-C-T EGFR c.2038C>T p.R680W Missense 17/28 -
17-37627130-A-C CDK12 c.1047-2A>C - IntronicSNV - 1/13
17-7577578-T-A TP53 c.703A>T p.N235Y Missense 7/11 -
17-7579528-C-G TP53 c.159G>C p.W53C Missense 4/11 -
2-48027541-G-A MSH6 c.2419G>A p.E807K Missense 4/10 -
17-37627130-A-G CDK12 c.1047-2A>G - IntronicSNV - 1/13
4-106156648-C-T TET2 c.1549C>T p.P517S Missense 3/11 -
2-209103826-C-A IDH1 c.1123G>T p.D375Y Missense 9/10 -
7-55224348-A-C EGFR c.1129A>C p.R377= Synonymous 9/28 -
10-43597976-G-A RET c.524G>A p.R175H Missense 3/20 -
11-108137952-G-T ATM c.2521G>T p.D841Y Missense 17/63 -
4-106157650-C-T TET2 c.2551C>T p.P851S Missense 3/11 -
4-106157699-A-G TET2 c.2600A>G p.Y867C Missense 3/11 -
4-106197120-A-T TET2 c.5453A>T p.K1818I Missense 11/11 -
4-106155428-A-G TET2 c.329A>G p.K110R Missense 3/11 -
17-29552212-G-T NF1 c.1945G>T p.E649* Nonsense 17/58 -
X-76954094-T-G ATRX c.157A>C p.N53H Missense 3/35 -
13-32913428-G-C BRCA2 c.4936G>C p.E1646Q Missense 11/27 -
4-106155475-G-T TET2 c.376G>T p.G126W Missense 3/11 -
17-41244688-G-T BRCA1 c.2860C>A p.L954I Missense 10/23 -
1-46740304-G-A RAD54L c.1784G>A p.W595* Nonsense 16/18 -
12-133252403-G-A POLE c.1024C>T p.H342Y Missense 11/49 -
17-29661913-T-C NF1 c.5870T>C p.V1957A Missense 40/58 -
10-8115780-A-C GATA3 c.1129A>C p.K377Q Missense 6/6 -
19-10602823-C-T KEAP1 c.755G>A p.W252* Nonsense 3/6 -
1-27100358-A-T ARID1A c.4070A>T p.Q1357L Missense 17/20 -
7-55224349-G-A EGFR c.1130G>A p.R377K Missense 9/28 -
17-29490291-G-T NF1 c.376G>T p.E126* Nonsense 4/58 -
17-7579455-C-G TP53 c.232G>C p.A78P Missense 4/11 -
5-112178759-G-A APC c.7468G>A p.D2490N Missense 16/16 -
1-27099440-A-G ARID1A c.3677A>G p.Y1226C Missense 14/20 -
1-27094376-G-C ARID1A c.3084G>C p.L1028= Synonymous 11/20 -
5-112178228-G-T APC c.6937G>T p.A2313S Missense 16/16 -
3-52442579-G-A BAP1 c.166C>T p.R56C Missense 4/17 -
17-7579437-C-T TP53 c.250G>A p.A84T Missense 4/11 -
7-55224350-G-T EGFR c.1131G>T p.R377S Missense 9/28 -
5-112154981-G-C APC c.1252G>C p.E418Q Missense 10/16 -
19-10610211-C-T KEAP1 c.499G>A p.V167I Missense 2/6 -
1-27087527-G-T ARID1A c.2101G>T p.G701C Missense 5/20 -
17-7577138-C-A TP53 c.800G>T p.R267L Missense 8/11 -
7-55266410-G-T EGFR c.2702G>T p.G901V Missense 23/28 -
7-55221711-G-A EGFR c.755G>A p.R252H Missense 7/28 -
7-55219001-C-T EGFR c.574C>T p.P192S Missense 5/28 -
7-55273044-C-T EGFR c.3367C>T p.P1123S Missense 28/28 -
2-178096223-G-C NFE2L2 c.1108C>G p.L370V Missense 5/5 -
19-10602796-C-G KEAP1 c.782G>C p.R261P Missense 3/6 -
19-10610235-C-A KEAP1 c.475G>T p.A159S Missense 2/6 -
19-10610285-G-A KEAP1 c.425C>T p.T142M Missense 2/6 -
19-10610246-A-G KEAP1 c.464T>C p.V155A Missense 2/6 -
19-10600347-A-T KEAP1 c.1508T>A p.M503K Missense 4/6 -
19-10602767-C-T KEAP1 c.811G>A p.V271M Missense 3/6 -
19-10602775-A-G KEAP1 c.803T>C p.L268P Missense 3/6 -
19-10610293-G-T KEAP1 c.417C>A p.F139L Missense 2/6 -
19-11138617-A-G SMARCA4 c.3373A>G p.R1125G Missense 24/35 -
19-11097649-C-T SMARCA4 c.829C>T p.P277S Missense 5/35 -
19-52714672-C-T PPP2R1A c.430C>T p.R144C Missense 4/15 -
19-52709242-C-A PPP2R1A c.196C>A p.L66I Missense 3/15 -
19-10610217-C-T KEAP1 c.493G>A p.D165N Missense 2/6 -
11-108235833-G-C ATM c.8875G>C p.D2959H Missense 62/63 -
11-108139190-T-G ATM c.2692T>G p.L898V Missense 18/63 -
19-11105622-G-A SMARCA4 c.1538G>A p.R513Q Missense 9/35 -
4-106164794-G-T TET2 c.3662G>T p.C1221F Missense 6/11 -
4-106196424-C-A TET2 c.4757C>A p.S1586* Nonsense 11/11 -
19-10599952-C-T KEAP1 c.1624G>A p.E542K Missense 5/6 -
7-55233034-G-A EGFR c.1784G>A p.C595Y Missense 15/28 -
16-2106225-G-A TSC2 c.628G>A p.A210T Missense 7/42 -
15-89824480-T-A FANCI c.1461T>A p.Y487* Nonsense 15/38 -
13-32910522-C-A BRCA2 c.2030C>A p.S677Y Missense 11/27 -
2-29519787-C-T ALK c.1784G>A p.W595* Nonsense 9/29 -
3-37090075-T-C MLH1 c.1964T>C p.I655T Missense 17/19 -
2-48027789-G-T MSH6 c.2667G>T p.Q889H Missense 4/10 -
16-2098636-A-G TSC2 c.20A>G p.K7R Missense 2/42 -
19-1207096-A-T STK11 c.184A>T p.K62* Nonsense 1/10 -
16-89882990-C-A FANCA c.34G>T p.G12C Missense 1/43 -
20-31023108-G-A ASXL1 c.2593G>A p.E865K Missense 13/13 -
19-1221319-C-A STK11 c.842C>A p.P281Q Missense 6/10 -
7-55211090-G-T EGFR c.333G>T p.M111I Missense 3/28 -
13-49037954-C-T RB1 c.2194C>T p.P732S Missense 21/27 -
X-66931295-C-A AR c.1937C>A p.A646D Missense 4/8 -
2-48033436-C-G MSH6 c.3740C>G p.T1247S Missense 8/10 -
7-6043687-G-C PMS2 c.166C>G p.L56V Missense 3/15 -
3-37061803-T-C MLH1 c.887T>C p.L296S Missense 11/19 -
17-7579505-T-A TP53 c.182A>T p.D61V Missense 4/11 -
5-137803334-A-C EGR1 c.1196A>C p.D399A Missense 2/2 -
5-137802449-C-T EGR1 c.311C>T p.S104F Missense 2/2 -
17-7577499-C-G TP53 c.782G>C p.S261T Missense 7/11 -
5-112102946-G-A APC c.281G>A p.R94H Missense 4/16 -
2-212812155-C-G ERBB4 c.421G>C p.E141Q Missense 3/28 -
5-112179567-G-A APC c.8276G>A p.R2759H Missense 16/16 -
17-7579338-C-T TP53 c.349G>A p.G117R Missense 4/11 -
12-58145493-G-T CDK4 c.8C>A p.T3N Missense 2/8 -
2-190728587-G-A PMS1 c.1975G>A p.A659T Missense 10/13 -
20-62839371-T-A MYT1 c.822T>A p.D274E Missense 7/23 -
19-1206953-A-G STK11 c.41A>G p.E14G Missense 1/10 -
2-29606679-G-A ALK c.1201C>T p.R401* Nonsense 5/29 -
22-41513542-A-G EP300 c.446A>G p.Q149R Missense 2/31 -
17-29562779-T-C NF1 c.3859T>C p.F1287L Missense 28/58 -
17-29653020-A-G NF1 c.5018A>G p.N1673S Missense 37/58 -
13-49033866-G-A RB1 c.2003G>A p.R668H Missense 20/27 -
17-59934544-G-A BRIP1 c.254C>T p.S85L Missense 4/20 -
17-29554593-A-G NF1 c.2378A>G p.N793S Missense 20/58 -
3-142281379-T-C ATR c.865A>G p.K289E Missense 4/47 -
8-133880432-A-G TG c.140A>G p.D47G Missense 2/48 -
15-43771665-C-A TP53BP1 c.718G>T p.D240Y Missense 7/28 -
8-133898869-G-C TG c.1252G>C p.D418H Missense 9/48 -
17-37865702-G-A ERBB2 c.571G>A p.A191T Missense 4/27 -
19-10600424-GC-G KEAP1 c.1430delG p.G477Afs*23 Frameshift 4/6 -
X-70360679-GGCA-G MED12 c.6256_6258delCAG p.Q2086del InFrameDeletion 42/45 -
7-116395529-G-A MET c.1822G>A p.E608K Missense 6/21 -
20-62839332-CGAG-C MYT1 c.801_803delGGA p.E273del InFrameDeletion 7/23 -
17-7579882-C-A TP53 c.31G>T p.E11* Nonsense 2/11 -
1-150551963-T-G MCL1 c.44A>C p.Y15S Missense 1/3 -
2-47641559-GTAA-G MSH2 c.942+2_942+4delTAA - IntronicDeletion - 5/15
X-70338639-G-T MED12 c.35G>T p.R12L Missense 1/45 -
17-37866345-G-A ERBB2 c.650G>A p.R217H Missense 6/27 -
20-31024254-C-T ASXL1 c.3739C>T p.R1247C Missense 13/13 -
16-23652445-C-A PALB2 c.34G>T p.E12* Nonsense 1/13 -
16-89845355-C-T FANCA c.1772G>A p.R591Q Missense 19/43 -
5-112175600-A-T APC c.4309A>T p.K1437* Nonsense 16/16 -
3-38180462-G-C MYD88 c.310G>C p.E91Q Missense 1/5 -
3-178948046-C-A PIK3CA c.2818C>A p.H940N Missense 20/21 -
16-89877395-T-C FANCA c.368A>G p.Q123R Missense 4/43 -
1-27023954-C-T ARID1A c.1060C>T p.Q354* Nonsense 1/20 -
7-140507801-C-A BRAF c.670G>T p.V224L Missense 5/18 -
8-133899397-G-A TG c.1780G>A p.D594N Missense 9/48 -
8-133900360-A-T TG c.2308A>T p.R770* Nonsense 10/48 -
5-176520283-G-C FGFR4 c.1202G>C p.R401P Missense 9/18 -
12-46231122-G-A ARID2 c.1042G>A p.D348N Missense 9/21 -
1-27023732-T-C ARID1A c.838T>C p.S280P Missense 1/20 -
16-23646905-A-C PALB2 c.962T>G p.L321* Nonsense 4/13 -
8-133898860-C-T TG c.1243C>T p.L415F Missense 9/48 -
7-140453172-A-C BRAF c.1763T>G p.L588R Missense 15/18 -
3-41267032-G-T CTNNB1 c.703G>T p.G235* Nonsense 5/15 -
4-106155335-CACA-C TET2 c.238_240delCAA p.Q80del InFrameDeletion 3/11 -
5-176518043-A-G FGFR4 c.541A>G p.T181A Missense 5/18 -
13-32914362-T-C BRCA2 c.5870T>C p.I1957T Missense 11/27 -
7-55210014-G-T EGFR c.124G>T p.G42C Missense 2/28 -
17-59763475-C-T BRIP1 c.2627G>A p.S876N Missense 19/20 -
2-29551229-C-A ALK c.1401G>T p.E467D Missense 6/29 -
10-43622031-G-T RET c.3048G>T p.L1016F Missense 19/20 -
13-32900672-G-A BRCA2 c.553G>A p.G185R Missense 7/27 -
7-116339680-G-A MET c.542G>A p.G181E Missense 2/21 -
7-6026574-C-T PMS2 c.1822G>A p.A608T Missense 11/15 -
8-133906135-C-T TG c.2962C>T p.R988C Missense 11/48 -
8-133894108-G-C TG c.639G>C p.R213S Missense 6/48 -
17-29657349-G-A NF1 c.5645G>A p.C1882Y Missense 39/58 -
4-72620810-A-C GC c.1049T>G p.L350R Missense 9/13 -
5-79966082-G-A MSH3 c.746G>A p.C249Y Missense 4/24 -
8-133900797-A-C TG c.2745A>C p.P915= Synonymous 10/48 -
8-133885353-G-T TG c.525G>T p.V175= Synonymous 5/48 -
8-133894800-C-T TG c.832C>T p.R278W Missense 7/48 -
8-133898954-C-G TG c.1337C>G p.A446G Missense 9/48 -
17-56787345-A-C RAD51C c.831A>C p.R277S Missense 5/9 -
5-137801689-G-T EGR1 c.239G>T p.S80I Missense 1/2 -
8-133894773-TC-T TG c.807delC p.T270Pfs*132 Frameshift 7/48 -
5-137801680-G-T EGR1 c.230G>T p.S77I Missense 1/2 -
8-133900673-GC-G TG c.2623delC p.Q875Nfs*91 Frameshift 10/48 -
3-178941908-G-A PIK3CA c.2227G>A p.D743N Missense 15/21 -
1-150550718-A-C MCL1 c.936+2T>G - IntronicSNV - 2/2
19-4101118-C-T MAP2K2 c.604G>A p.V202M Missense 6/11 -
3-178916894-T-C PIK3CA c.281T>C p.L94P Missense 2/21 -
13-32915158-C-G BRCA2 c.6666C>G p.Y2222* Nonsense 11/27 -
8-48855917-C-T PRKDC c.818G>A p.R273H Missense 10/87 -
8-48872616-C-A PRKDC c.71G>T p.R24L Missense 1/87 -
17-41245636-C-A BRCA1 c.1912G>T p.E638* Nonsense 10/23 -
13-25020890-A-G PARP4 c.3295T>C p.C1099R Missense 27/34 -
12-46243560-G-T ARID2 c.1912+1G>T - IntronicSNV - 14/20
1-11168236-A-C MTOR c.7634+2T>G - IntronicSNV - 57/57
9-35079436-A-C FANCG c.84+2T>G - IntronicSNV - 1/13
9-5054886-T-G JAK2 c.936+2T>G - IntronicSNV - 7/24
2-39347475-A-C SOS1 c.87+2T>G - IntronicSNV - 1/22
20-30309456-A-C BCL2L1 c.564+2T>G - IntronicSNV - 2/2
8-6264212-T-G MCPH1 c.22+2T>G - IntronicSNV - 1/13
3-41267354-T-G CTNNB1 c.936+2T>G - IntronicSNV - 6/14
11-69588790-A-C FGF4 c.444+2T>G - IntronicSNV - 2/2
6-35428397-T-G FANCE c.1383+2T>G - IntronicSNV - 8/9
17-37876038-A-T ERBB2 c.1899-2A>T - IntronicSNV - 15/26
12-46231201-G-A ARID2 c.1120+1G>A - IntronicSNV - 9/20
1-11199588-A-C MTOR c.4998+2T>G - IntronicSNV - 35/57
13-25020818-C-A PARP4 c.3366+1G>T - IntronicSNV - 27/33
17-29497016-G-T NF1 c.586+1G>T - IntronicSNV - 5/57
10-43596171-G-T RET c.337+1G>T - IntronicSNV - 2/19
12-133244940-A-C POLE c.2173+2T>G - IntronicSNV - 19/48
8-38282025-A-C FGFR1 c.936+2T>G - IntronicSNV - 7/17
3-142253921-C-A ATR c.3945+1G>T - IntronicSNV - 21/46
17-29576138-G-T NF1 c.4110+1G>T - IntronicSNV - 30/57
19-1222006-G-A STK11 c.920+1G>A - IntronicSNV - 7/9
2-39294893-A-AC SOS1 c.88_88dupG - SpliceAcceptorInsertion - 1/22
1-65351941-C-A JAK1 c.6+1G>T - IntronicSNV - 2/24
19-11102000-G-T SMARCA4 c.1419+1G>T - IntronicSNV - 8/34
16-2137924-TCCCTGCAGTGCAGGAAAGGTAGGGCCGGGTGGGG-T TSC2 c.5068+27_5069-47del34 - SpliceDonorDeletion - 39/41
12-69214156-T-G MDM2 c.358+2T>G - IntronicSNV - 5/10
19-17943326-A-C JAK3 c.2680+2T>G - IntronicSNV - 19/23
19-45924434-A-C ERCC1 c.321+2T>G - IntronicSNV - 3/9
16-2106772-T-G TSC2 c.774+2T>G - IntronicSNV - 8/41
16-89858333-A-C FANCA c.1225+2T>G - IntronicSNV - 13/42
3-52613068-A-C PBRM1 c.3458+2T>G - IntronicSNV - 22/29
19-45873389-A-C ERCC2 c.105+2T>G - IntronicSNV - 2/22
5-176518107-T-G FGFR4 c.603+2T>G - IntronicSNV - 5/17
3-10128950-T-G FANCD2 c.3466+2T>G - IntronicSNV - 34/43
13-25029154-C-A PARP4 c.2758+1G>T - IntronicSNV - 22/33
X-48772295-AC-A PIM2 c.595+1delG - IntronicDeletion 4/6 -
7-140476711-C-T BRAF c.1694+1G>A - IntronicSNV - 13/17
13-48937094-G-A RB1 c.861+1G>A - IntronicSNV - 8/26
19-30308449-G-T CCNE1 c.462+1G>T - IntronicSNV - 6/11
17-29657518-T-A NF1 c.5812+2T>A - IntronicSNV - 39/57
X-70347318-G-T MED12 c.2981+1G>T - IntronicSNV - 21/44
12-133220421-A-C POLE c.4290+2T>G - IntronicSNV - 33/48
20-62854714-T-C MYT1 c.2528+2T>C - IntronicSNV - 16/22
4-55961743-C-A KDR c.2817+1G>T - IntronicSNV - 20/29
13-25021129-GAATAACAAACTCTGCGTCTTCTTACC-G PARP4 c.3285_3285+25del26 - SpliceDonorDeletion 26/34 26/33
13-25021152-TACC-T PARP4 c.3285_3285+2delGGT - SpliceDonorDeletion 26/34 26/33
1-11273450-ACTCAC-A MTOR c.3285+1_3285+5delGTGAG - SpliceDonorDeletion 21/58 21/57
3-52584762-C-A PBRM1 c.4359+1G>T - IntronicSNV - 28/29
19-10599866-A-T KEAP1 c.1708+2T>A - IntronicSNV - 5/5
22-29121229-A-C CHEK2 c.444+2T>G - IntronicSNV - 3/14
3-52584435-A-C PBRM1 c.4576+2T>G - IntronicSNV - 29/29
5-56111883-G-A MAP3K1 c.482+1G>A - IntronicSNV - 1/19
1-27099480-T-G ARID1A c.3715+2T>G - IntronicSNV - 14/19
19-10610070-C-A KEAP1 c.639+1G>T - IntronicSNV - 2/5
13-25021136-AAACTCTGCGTCTTCTTACC-A PARP4 c.3285_3285+18del19 - SpliceDonorDeletion 26/34 26/33
5-79960970-A-C MSH3 c.367A>C p.K123Q Missense 3/24 -
2-39262424-C-G SOS1 c.1003G>C p.V335L Missense 8/23 -
2-39283973-G-C SOS1 c.380C>G p.S127C Missense 4/23 -
17-78896612-A-T RPTOR c.2609A>T p.H870L Missense 22/34 -
2-39250081-C-G SOS1 c.1488G>C p.M496I Missense 10/23 -
19-11134291-C-A SMARCA4 c.2957C>A p.A986D Missense 20/35 -
8-133925390-G-A TG c.4258G>A p.E1420K Missense 20/48 -
3-41266176-A-T CTNNB1 c.173A>T p.D58V Missense 3/15 -
3-41266607-C-A CTNNB1 c.404C>A p.A135E Missense 4/15 -
12-56481367-C-A ERBB3 c.554C>A p.P185H Missense 5/28 -
15-89837147-C-G FANCI c.2375C>G p.A792G Missense 23/38 -
20-31021251-G-A ASXL1 c.1250G>A p.R417Q Missense 12/13 -
19-10599947-C-G KEAP1 c.1629G>C p.T543= Synonymous 5/6 -
3-41268748-G-T CTNNB1 c.986G>T p.R329M Missense 7/15 -
17-11998902-C-A MAP2K4 c.404C>A p.S135* Nonsense 4/11 -
7-148543635-T-A EZH2 c.173A>T p.Q58L Missense 3/20 -
16-2121553-C-T TSC2 c.1882C>T p.R628C Missense 18/42 -
7-148516701-C-A EZH2 c.986G>T p.C329F Missense 9/20 -
8-133913666-G-A TG c.3502G>A p.A1168T Missense 16/48 -
9-21971006-C-A CDKN2A c.352G>T p.A118S Missense 2/3 -
21-36259336-A-C RUNX1 c.155T>G p.M52R Missense 4/9 -
1-27023567-C-T ARID1A c.673C>T p.P225S Missense 1/20 -
7-55259551-A-T EGFR c.2609A>T p.H870L Missense 21/28 -
1-27088766-C-G ARID1A c.2375C>G p.S792C Missense 7/20 -
17-7577089-TGCG-T TP53 c.847_849delCGC p.R283del InFrameDeletion 8/11 -
2-47637377-A-C MSH2 c.511A>C p.R171= Synonymous 3/16 -
10-43610066-A-C RET c.2018A>C p.E673A Missense 11/20 -
11-108203607-C-T ATM c.7907C>T p.T2636I Missense 53/63 -
11-108114727-G-T ATM c.544G>T p.V182F Missense 6/63 -
2-47637429-A-T MSH2 c.563A>T p.E188V Missense 3/16 -
18-39537639-A-T PIK3C3 c.173A>T p.Y58F Missense 2/25 -
20-62839582-G-A MYT1 c.1033G>A p.E345K Missense 7/23 -
18-39576672-A-C PIK3C3 c.962A>C p.Y321S Missense 9/25 -
17-29496917-A-G NF1 c.488A>G p.E163G Missense 5/58 -
17-29587475-T-C NF1 c.4519T>C p.L1507= Synonymous 34/58 -
16-2134988-T-G TSC2 c.4530T>G p.F1510L Missense 35/42 -
2-47630358-C-G MSH2 c.28C>G p.Q10E Missense 1/16 -
12-133263880-G-C POLE c.22C>G p.R8G Missense 1/49 -
12-133257819-G-T POLE c.109C>A p.R37= Synonymous 2/49 -
16-2103371-T-G TSC2 c.254T>G p.V85G Missense 4/42 -
19-52722998-A-C PPP2R1A c.1183A>C p.I395L Missense 10/15 -
2-47641446-A-C MSH2 c.831A>C p.L277F Missense 5/16 -
13-25043248-T-C PARP4 c.2047A>G p.I683V Missense 17/34 -
13-25029340-A-C PARP4 c.2573T>G p.L858R Missense 22/34 -
7-55220247-A-G EGFR c.637A>G p.I213V Missense 6/28 -
17-35633931-A-C ACACA c.797T>G p.F266C Missense 7/56 -
17-7578224-T-G TP53 c.625A>C p.R209= Synonymous 6/11 -
4-1806237-T-G FGFR3 c.1256T>G p.L419R Missense 9/18 -
7-55224514-A-C EGFR c.1196A>C p.K399T Missense 10/28 -
7-55221764-T-G EGFR c.808T>G p.Y270D Missense 7/28 -
7-55229242-G-A EGFR c.1549G>A p.G517S Missense 13/28 -
5-176517602-C-A FGFR4 c.303C>A p.C101* Nonsense 3/18 -
11-94197348-C-T MRE11 c.1156G>A p.V386M Missense 11/20 -
20-62837042-G-T MYT1 c.286G>T p.D96Y Missense 6/23 -
11-94204759-G-T MRE11 c.826C>A p.P276T Missense 8/20 -
11-94153338-C-A MRE11 c.2080G>T p.D694Y Missense 20/20 -
11-108198390-C-A ATM c.6994C>A p.L2332I Missense 48/63 -
3-142177838-C-A ATR c.7465G>T p.E2489* Nonsense 44/47 -
3-142286932-C-A ATR c.124G>T p.D42Y Missense 2/47 -
13-25043167-C-A PARP4 c.2128G>T p.A710S Missense 17/34 -
3-10107099-G-T FANCD2 c.2190G>T p.L730= Synonymous 24/44 -
15-91326156-C-A BLM c.2660C>A p.P887Q Missense 13/22 -
3-142279130-G-T ATR c.1516C>A p.H506N Missense 6/47 -
11-69514218-T-C FGF19 c.463A>G p.K155E Missense 3/3 -
5-112175204-G-A APC c.3913G>A p.A1305T Missense 16/16 -
4-106155763-C-T TET2 c.664C>T p.H222Y Missense 3/11 -
19-18274188-G-T PIK3R2 c.1406G>T p.R469L Missense 11/16 -
5-176519394-TGGA-T FGFR4 c.802_804delGAG p.E268del InFrameDeletion 7/18 -
5-79950724-G-GCCGCAGCGGCCGCAGCGC MSH3 c.186_187insGCCGCAGCGCCCGCAGCG p.A62_P63insAAAPAA InFrameInsertion 1/24 -
17-35470115-A-ATGG ACACA c.6359_6360insCCA p.P2120_P2121insH InFrameInsertion 51/56 -
17-37649023-GGA-TGG CDK12 c.2128_2130delGGAinsTGG p.G710W Missense 4/14 -
5-79950714-GGCC-G MSH3 c.171_173delCGC p.A62del InFrameDeletion 1/24 -
20-62851174-G-T MYT1 c.2080G>T p.G694C Missense 13/23 -
X-76763843-C-A ATRX c.7465G>T p.G2489W Missense 35/35 -
1-27023927-G-A ARID1A c.1033G>A p.A345T Missense 1/20 -
15-91293009-A-C BLM c.511A>C p.T171P Missense 3/22 -
5-1294170-T-G TERT c.831A>C p.R277S Missense 2/16 -
20-62839705-G-A MYT1 c.1156G>A p.A386T Missense 7/23 -
13-25075932-T-A PARP4 c.173A>T p.Q58L Missense 3/34 -
2-39278323-G-T SOS1 c.826C>A p.H276N Missense 6/23 -
11-108124623-G-T ATM c.1981G>T p.D661Y Missense 13/63 -
17-29541592-C-A NF1 c.1516C>A p.L506I Missense 13/58 -
16-2134977-T-C TSC2 c.4519T>C p.S1507P Missense 35/42 -
12-133225984-C-T POLE c.3913G>A p.G1305R Missense 31/49 -
4-106156061-A-C TET2 c.962A>C p.Q321P Missense 3/11 -
19-18266717-C-G PIK3R2 c.28C>G p.R10G Missense 2/16 -
7-55269468-G-T EGFR c.3155G>T p.R1052I Missense 26/28 -
12-25398230-T-G KRAS c.89A>C p.D30A Missense 2/5 -
12-133219123-T-G POLE c.4921A>C p.T1641P Missense 37/49 -
12-133219250-A-C POLE c.4794T>G p.S1598R Missense 37/49 -
3-52437593-A-C BAP1 c.1568T>G p.V523G Missense 13/17 -
21-39775547-A-C ERG c.473T>G p.L158W Missense 4/10 -
19-4099364-T-G MAP2K2 c.754A>C p.S252R Missense 7/11 -
12-25380292-G-A KRAS c.166C>T p.L56F Missense 3/5 -
5-112164637-G-A APC c.1711G>A p.A571T Missense 14/16 -
9-5029859-C-A JAK2 c.303C>A p.V101= Synonymous 4/25 -
7-140482889-A-C BRAF c.1246T>G p.L416V Missense 10/18 -
12-133238179-A-G POLE c.2798T>C p.V933A Missense 24/49 -
2-213403200-T-C ERBB4 c.55A>G p.T19A Missense 1/28 -
1-27023184-A-G ARID1A c.290A>G p.E97G Missense 1/20 -
1-27023852-C-G ARID1A c.958C>G p.P320A Missense 1/20 -
1-27023856-A-C ARID1A c.962A>C p.Q321P Missense 1/20 -
2-212989494-C-G ERBB4 c.217G>C p.D73H Missense 2/28 -
5-112090609-C-G APC c.22C>G p.Q8E Missense 2/16 -
2-212576845-T-G ERBB4 c.1054A>C p.N352H Missense 9/28 -
15-90628535-A-G IDH2 c.1052T>C p.V351A Missense 8/11 -
5-176516604-A-G FGFR4 c.1A>G p.M1? Missense 2/18 -
4-55948792-G-A KDR c.3673C>T p.Q1225* Nonsense 28/30 -
4-55980426-C-A KDR c.665G>T p.R222M Missense 6/30 -
2-212537888-C-A ERBB4 c.1716+1G>T - IntronicSNV - 14/27
4-84393369-GAATACCTTTTTGACATTTGAT-G ABRAXAS1 c.267_282+5del21 - SpliceDonorDeletion 4/9 4/8
17-29580020-T-A NF1 c.4173+2T>A - IntronicSNV - 31/57
17-29664900-T-G NF1 c.6704+2T>G - IntronicSNV - 44/57
20-62853402-T-G MYT1 c.2396+2T>G - IntronicSNV - 14/22
15-99434668-G-A IGF1R c.755G>A p.R252H Missense 3/21 -
19-10610636-T-G KEAP1 c.74A>C p.E25A Missense 2/6 -
19-11097101-G-A SMARCA4 c.592G>A p.D198N Missense 4/35 -
2-42528396-G-A EML4 c.1505G>A p.S502N Missense 14/23 -
7-148523660-C-T EZH2 c.793G>A p.D265N Missense 8/20 -
3-52713676-C-A PBRM1 c.52G>T p.D18Y Missense 2/30 -
2-42472774-T-G EML4 c.155T>G p.L52R Missense 2/23 -
21-36253010-C-A RUNX1 c.352G>T p.V118L Missense 5/9 -
3-52678797-A-T PBRM1 c.822T>A p.N274K Missense 9/30 -
5-112173864-T-G APC c.2573T>G p.I858S Missense 16/16 -
7-55227886-C-A EGFR c.1353C>A p.R451= Synonymous 12/28 -
5-67593422-G-A PIK3R1 c.2168G>A p.R723K Missense 16/16 -
15-43749215-G-C TP53BP1 c.1591C>G p.P531A Missense 12/28 -
15-43724565-C-T TP53BP1 c.3502G>A p.V1168I Missense 17/28 -
17-41245530-T-G BRCA1 c.2018A>C p.E673A Missense 10/23 -
12-56487915-GCTT-G ERBB3 c.1649_1651delTCT p.F550del InFrameDeletion 14/28 -
8-133978900-C-CCCCCCCCCA TG c.5644_5645insCCCCCCCCA p.H1882delinsPPPN MultiAAMissense 30/48 -
3-41275322-G-C CTNNB1 c.1488G>C p.K496N Missense 9/15 -
12-1042173-C-A RAD52 c.52G>T p.A18S Missense 2/12 -
7-55272982-C-T EGFR c.3305C>T p.A1102V Missense 28/28 -
16-2106222-A-C TSC2 c.625A>C p.T209P Missense 7/42 -
11-108119790-A-C ATM c.1196A>C p.H399P Missense 9/63 -
3-51978834-A-T PARP3 c.563A>T p.Q181L Missense 5/11 -
2-47637410-G-T MSH2 c.544G>T p.D182Y Missense 3/16 -
8-48866264-T-C PRKDC c.637A>G p.R213G Missense 7/87 -
4-1803619-T-G FGFR3 c.797T>G p.V266G Missense 7/18 -
5-1293745-A-C TERT c.1256T>G p.V419G Missense 2/16 -
5-112176705-T-G APC c.5414T>G p.F1805C Missense 16/16 -
1-46743787-C-T RAD54L c.2077C>T p.P693S Missense 18/18 -
17-78796035-C-A RPTOR c.925C>A p.L309M Missense 8/34 -
17-41234507-T-G BRCA1 c.4271A>C p.Q1424P Missense 12/23 -
16-2121885-T-G TSC2 c.2047T>G p.S683A Missense 19/42 -
16-2122258-T-G TSC2 c.2114T>G p.V705G Missense 20/42 -
16-2115626-T-G TSC2 c.1706T>G p.V569G Missense 16/42 -
12-25398254-T-G KRAS c.65A>C p.Q22P Missense 2/5 -
17-29527582-T-G NF1 c.1031T>G p.L344R Missense 9/58 -
6-37140801-A-C PIM1 c.637A>C p.I213L Missense 5/6 -
11-9595908-G-C WEE1 c.428G>C p.C143S Missense 1/11 -
7-55219037-G-A EGFR c.610G>A p.E204K Missense 5/28 -
17-29541590-A-C NF1 c.1514A>C p.K505T Missense 13/58 -
3-52436426-T-G BAP1 c.2068A>C p.N690H Missense 17/17 -
3-138456692-G-T PIK3CB c.658C>A p.P220T Missense 6/24 -
8-90958434-A-C NBN c.2004T>G p.T668= Synonymous 13/16 -
17-59761150-T-G BRIP1 c.3257A>C p.K1086T Missense 20/20 -
11-77103499-T-G PAK1 c.67A>C p.M23L Missense 2/15 -
2-213403196-A-C ERBB4 c.59T>G p.V20G Missense 1/28 -
5-112176934-A-AACCCCCCCC APC c.5644_5645insCCCCCCCCA p.L1881_R1882insTPP InFrameInsertion 16/16 -
5-79950708-TGCAGCGGCCGCAGCGGCCGCAGCGCCCC-CG MSH3 c.162_190delinsCG p.A57_A65del InFrameDeletion 1/24 -
5-112174548-A-C APC c.3257A>C p.H1086P Missense 16/16 -
2-190656602-A-C PMS1 c.67A>C p.S23R Missense 2/13 -
19-45924477-G-C ERCC1 c.280C>G p.P94A Missense 3/10 -
17-78865540-T-G RPTOR c.2004T>G p.S668R Missense 18/34 -
7-81386533-A-C HGF c.454T>G p.W152G Missense 4/18 -
9-21971141-C-G CDKN2A c.217G>C p.A73P Missense 2/3 -
17-29490282-A-C NF1 c.367A>C p.T123P Missense 4/58 -
17-59938836-T-G BRIP1 c.65A>C p.Y22S Missense 2/20 -
2-215646125-A-C BARD1 c.473T>G p.V158G Missense 4/11 -
3-52440389-C-A BAP1 c.663G>T p.E221D Missense 9/17 -
15-90628533-T-G IDH2 c.1054A>C p.T352P Missense 8/11 -
5-79970805-T-G MSH3 c.1031T>G p.V344G Missense 7/24 -
9-135779178-T-G TSC1 c.2068A>C p.T690P Missense 17/23 -
12-133250274-A-C POLE c.1246T>G p.Y416D Missense 13/49 -
3-138426017-T-G PIK3CB c.1514A>C p.Y505S Missense 11/24 -
1-27023819-C-A ARID1A c.925C>A p.Q309K Missense 1/20 -
5-176523075-G-T FGFR4 c.1839G>T p.L613= Synonymous 14/18 -
13-32903616-A-C BRCA2 c.668A>C p.H223P Missense 8/27 -
3-10076418-G-T FANCD2 c.313G>T p.E105* Nonsense 5/44 -
11-108139264-T-A ATM c.2766T>A p.D922E Missense 18/63 -
9-5054763-T-G JAK2 c.815T>G p.V272G Missense 7/25 -
5-112137000-A-C APC c.754A>C p.T252P Missense 8/16 -
16-2108852-C-A TSC2 c.953C>A p.S318Y Missense 10/42 -
3-52440894-C-T BAP1 c.610G>A p.D204N Missense 8/17 -
1-11318606-A-C MTOR c.207T>G p.H69Q Missense 3/58 -
1-27105667-G-T ARID1A c.5278G>T p.E1760* Nonsense 20/20 -
1-162724443-G-T DDR2 c.215G>T p.W72L Missense 5/18 -
1-226566929-G-T PARP1 c.1659C>A p.F553L Missense 12/23 -
4-55984826-G-T KDR c.303C>A p.Y101* Nonsense 3/30 -
17-59885991-G-C BRIP1 c.755C>G p.T252R Missense 7/20 -
4-1803612-A-C FGFR3 c.790A>C p.T264P Missense 7/18 -
3-138403486-C-A PIK3CB c.2296G>T p.V766F Missense 17/24 -
5-80064785-A-G MSH3 c.2216A>G p.N739S Missense 15/24 -
7-55227834-G-T EGFR c.1301G>T p.G434V Missense 12/28 -
5-80109493-G-A MSH3 c.2746G>A p.A916T Missense 20/24 -
4-55968157-G-A KDR c.2173C>T p.R725C Missense 15/30 -
4-106180802-A-G TET2 c.3830A>G p.D1277G Missense 7/11 -
12-58145412-T-G CDK4 c.89A>C p.H30P Missense 2/8 -
1-27023202-C-G ARID1A c.308C>G p.S103W Missense 1/20 -
16-2106654-C-A TSC2 c.658C>A p.Q220K Missense 8/42 -
3-10081471-A-C FANCD2 c.637A>C p.T213P Missense 9/44 -
19-45868349-C-G ERCC2 c.428G>C p.R143P Missense 6/23 -
19-45872000-A-C ERCC2 c.248T>G p.V83G Missense 5/23 -
9-80537095-G-A GNAQ c.303C>T p.Y101= Synonymous 2/7 -
7-81372699-G-C HGF c.835C>G p.R279G Missense 7/18 -
7-81386583-C-A HGF c.404G>T p.S135I Missense 4/18 -
7-81388113-C-A HGF c.262G>T p.V88F Missense 3/18 -
7-81332027-A-G HGF c.2057T>C p.M686T Missense 18/18 -
7-81336617-A-C HGF c.1605T>G p.C535W Missense 14/18 -
7-81386553-C-A HGF c.434G>T p.S145I Missense 4/18 -
2-212295777-C-A ERBB4 c.2536G>T p.A846S Missense 21/28 -
X-70339672-A-G MED12 c.341A>G p.N114S Missense 3/45 -
1-46733254-G-T RAD54L c.1015G>T p.V339L Missense 9/18 -
17-29663414-G-T NF1 c.6070G>T p.G2024* Nonsense 41/58 -
7-92244469-C-A CDK6 c.966G>T p.E322D Missense 8/8 -
7-55218996-G-T EGFR c.569G>T p.C190F Missense 5/28 -
7-140439692-T-C BRAF c.2047A>G p.S683G Missense 17/18 -
13-25017813-A-G PARP4 c.3422T>C p.L1141P Missense 28/34 -
13-25029299-C-T PARP4 c.2614G>A p.A872T Missense 22/34 -
17-29554266-C-A NF1 c.2282C>A p.A761E Missense 19/58 -
8-6302331-C-A MCPH1 c.1088C>A p.S363Y Missense 8/14 -
20-57480487-C-T GNAS c.482C>T p.A161V Missense 6/13 -
X-70338639-G-C MED12 c.35G>C p.R12P Missense 1/45 -
19-11136108-G-T SMARCA4 c.3092G>T p.G1031V Missense 22/35 -
19-11097162-C-G SMARCA4 c.653C>G p.P218R Missense 4/35 -
19-11101931-C-G SMARCA4 c.1351C>G p.R451G Missense 8/35 -
2-212295709-C-G ERBB4 c.2604G>C p.L868F Missense 21/28 -
2-212568860-G-T ERBB4 c.1258C>A p.L420M Missense 11/28 -
2-212495264-C-A ERBB4 c.2002G>T p.G668C Missense 17/28 -
2-16082222-G-C MYCN c.36G>C p.M12I Missense 2/3 -
2-16086185-T-A MYCN c.1361T>A p.L454* Nonsense 3/3 -
1-162741853-C-A DDR2 c.1544C>A p.P515H Missense 13/18 -
19-11135016-G-A SMARCA4 c.2983G>A p.V995I Missense 21/35 -
1-46736405-G-A RAD54L c.1117G>A p.D373N Missense 10/18 -
X-70340822-A-C MED12 c.555A>C p.E185D Missense 5/45 -
14-45645696-G-A FANCM c.3739G>A p.E1247K Missense 14/23 -
17-41245333-T-G BRCA1 c.2215A>C p.K739Q Missense 10/23 -
3-142274961-G-A ATR c.2099C>T p.S700F Missense 10/47 -
14-45665709-A-C FANCM c.5675A>C p.E1892A Missense 21/23 -
7-55211011-T-G EGFR c.254T>G p.V85G Missense 3/28 -
3-142281413-T-G ATR c.831A>C p.L277F Missense 4/47 -
5-1294897-A-G TERT c.208T>C p.S70P Missense 1/16 -
5-1293805-T-G TERT c.1196A>C p.N399T Missense 2/16 -
5-176700678-C-A NSD1 c.5515C>A p.Q1839K Missense 17/23 -
1-27107003-C-A ARID1A c.6614C>A p.A2205D Missense 20/20 -
17-29486079-A-C NF1 c.256A>C p.I86L Missense 3/58 -
8-48794028-A-C PRKDC c.5015T>G p.F1671L Nonsense 39/87 -
17-29548919-G-C NF1 c.1693G>C p.A565P Missense 15/58 -
9-80537175-A-C GNAQ c.223T>G p.F75V Missense 2/7 -
14-45623201-A-C FANCM c.1129A>C p.M377L Missense 6/23 -
5-176517819-C-G FGFR4 c.429C>G p.P143= Synonymous 4/18 -
14-45623160-T-G FANCM c.1088T>G p.I363S Missense 6/23 -
17-7573987-G-C TP53 c.1040C>G p.A347G Missense 10/11 -
14-45642295-T-C FANCM c.2198T>C p.L733P Missense 13/23 -
14-45642363-C-A FANCM c.2266C>A p.R756S Missense 13/23 -
1-9770628-A-C PIK3CD c.115A>C p.N39H Missense 3/24 -
1-9770535-C-G PIK3CD c.22C>G p.P8A Missense 3/24 -
20-57485747-A-C GNAS c.1048A>C p.T350P Missense 13/13 -
5-176518711-T-G FGFR4 c.629T>G p.V210G Missense 6/18 -
X-53239606-T-G KDM5C c.1736A>C p.H579P Missense 12/26 -
17-29685987-G-T NF1 c.8114G>T p.S2705I Missense 56/58 -
9-5054747-A-C JAK2 c.799A>C p.T267P Missense 7/25 -
17-41246352-T-G BRCA1 c.1196A>C p.H399P Missense 10/23 -
1-9784036-G-C PIK3CD c.2604G>C p.L868= Synonymous 21/24 -
12-133215748-G-T POLE c.5515C>A p.R1839S Missense 40/49 -
17-29553453-G-T NF1 c.2002G>T p.D668Y Missense 18/58 -
19-18274133-C-G PIK3R2 c.1351C>G p.Q451E Missense 11/16 -
22-24135769-A-C SMARCB1 c.256A>C p.T86P Missense 3/9 -
1-46714216-G-C RAD54L c.36G>C p.K12N Missense 2/18 -
22-24129441-G-A SMARCB1 c.85G>A p.G29S Missense 1/9 -
17-29528080-C-A NF1 c.1088C>A p.P363Q Missense 10/58 -
3-10107175-C-A FANCD2 c.2266C>A p.L756I Missense 24/44 -
X-70347744-G-A MED12 c.2983G>A p.D995N Missense 22/45 -
22-24145550-G-T SMARCB1 c.569G>T p.R190L Missense 5/9 -
9-5029897-A-G JAK2 c.341A>G p.Y114C Missense 4/25 -
X-53240768-C-T KDM5C c.1312G>A p.V438I Missense 10/26 -
3-10081026-A-C FANCD2 c.555A>C p.R185S Missense 8/44 -
15-49776573-T-G FGF7 c.457T>G p.S153A Missense 4/4 -
1-27024023-A-C ARID1A c.1129A>C p.T377P Missense 1/20 -
1-27058028-A-C ARID1A c.1736A>C p.Y579S Missense 3/20 -
16-30128266-C-A MAPK3 c.966G>T p.E322D Missense 7/9 -
13-25067787-C-A PARP4 c.826G>T p.G276C Missense 8/34 -
9-5123044-G-C JAK2 c.3100G>C p.A1034P Missense 23/25 -
20-62839637-T-G MYT1 c.1088T>G p.V363G Missense 7/23 -
3-10128904-T-C FANCD2 c.3422T>C p.I1141T Missense 34/44 -
1-27102089-T-G ARID1A c.5015T>G p.V1672G Missense 19/20 -
X-53226961-C-T KDM5C c.2614G>A p.D872N Missense 18/26 -
22-50355272-C-G PIM3 c.429C>G p.D143E Missense 4/6 -
7-116411636-G-T MET c.2815G>T p.V939F Missense 13/21 -
7-116371843-C-G MET c.1322C>G p.S441C Missense 3/21 -
7-116380037-C-T MET c.1426C>T p.H476Y Missense 4/21 -
7-116339752-A-G MET c.614A>G p.Y205C Missense 2/21 -
10-89692770-T-G PTEN c.254T>G p.V85G Missense 5/9 -
2-178098846-C-T NFE2L2 c.199G>A p.E67K Missense 2/5 -
14-45624578-G-A FANCM c.1312G>A p.D438N Missense 8/23 -
2-209110124-G-A IDH1 c.439C>T p.P147S Missense 5/10 -
13-32950906-C-G BRCA2 c.8732C>G p.A2911G Missense 21/27 -
8-48869976-A-T PRKDC c.170T>A p.L57* Nonsense 2/87 -
13-32907057-T-A BRCA2 c.1442T>A p.I481N Missense 10/27 -
12-46243947-G-C ARID2 c.2041G>C p.V681L Missense 15/21 -
13-32911244-A-G BRCA2 c.2752A>G p.N918D Missense 11/27 -
12-46245726-G-C ARID2 c.3820G>C p.G1274R Missense 15/21 -
8-48843337-T-G PRKDC c.1787A>C p.E596A Missense 17/87 -
19-17952286-T-G JAK3 c.1054A>C p.T352P Missense 8/24 -
14-45605457-T-G FANCM c.223T>G p.F75V Missense 1/23 -
10-43604671-T-G RET c.1256T>G p.F419C Missense 6/20 -
13-32915211-T-G BRCA2 c.6719T>G p.L2240R Missense 11/27 -
11-108201101-C-T ATM c.7468C>T p.L2490F Missense 50/63 -
1-27089574-C-A ARID1A c.2530C>A p.Q844K Missense 8/20 -
5-112102922-A-G APC c.257A>G p.K86R Missense 4/16 -
5-112173612-A-C APC c.2321A>C p.D774A Missense 16/16 -
1-46738151-A-C RAD54L c.1183A>C p.R395= Synonymous 11/18 -
2-42543140-C-A EML4 c.2006C>A p.S669Y Missense 18/23 -
22-29095915-C-T CHEK2 c.919G>A p.G307R Missense 9/15 -
11-108123597-A-C ATM c.1856A>C p.N619T Missense 12/63 -
8-133899565-A-C TG c.1948A>C p.R650= Synonymous 9/48 -
12-133249238-C-A POLE c.1661G>T p.S554I Missense 15/49 -
2-215661785-C-A BARD1 c.215G>T p.S72I Missense 2/11 -
1-11300487-G-T MTOR c.1659C>A p.R553= Synonymous 11/58 -
4-106196978-G-T TET2 c.5311G>T p.G1771C Missense 11/11 -
1-162729669-C-G DDR2 c.755C>G p.P252R Missense 8/18 -
13-32910788-G-T BRCA2 c.2296G>T p.A766S Missense 11/27 -
13-32910708-A-G BRCA2 c.2216A>G p.H739R Missense 11/27 -
3-52668618-C-A PBRM1 c.1301G>T p.R434L Missense 12/30 -
3-52637570-C-T PBRM1 c.2746G>A p.E916K Missense 18/30 -
1-27087886-C-T ARID1A c.2173C>T p.P725S Missense 6/20 -
16-2103425-C-G TSC2 c.308C>G p.A103G Missense 4/42 -
5-112175975-G-A APC c.4684G>A p.D1562N Missense 16/16 -
17-41244162-A-G BRCA1 c.3386T>C p.I1129T Missense 10/23 -
12-133249350-G-A POLE c.1549C>T p.P517S Missense 15/49 -
15-66729103-AACCCGC-A MAP2K1 c.313_318delCCCGCA p.P105_A106del InFrameDeletion 3/11 -
5-79950745-CCAGCTCCCG-C MSH3 c.201_209delAGCTCCCGC p.A68_A70del InFrameDeletion 1/24 -
14-45605403-TTGC-T FANCM c.171_173delGCT p.L57_L58delinsF MultiAAMissense 1/23 -
19-1226589-CA-TG STK11 c.1245_1246delinsTG p.K416E Missense 9/10 -
2-178098062-GGGC-G NFE2L2 c.316_318delGCC p.A106del InFrameDeletion 3/5 -
19-52709253-GGCA-G PPP2R1A c.209_211delCAG p.A70del InFrameDeletion 3/15 -
10-43596023-GCCC-G RET c.190_192delCCC p.P64del InFrameDeletion 2/20 -
1-11182127-A-C MTOR c.6719T>G p.V2240G Missense 48/58 -
10-43606703-G-A RET c.1312G>A p.V438I Missense 7/20 -
4-1801510-A-G FGFR3 c.416A>G p.D139G Missense 4/18 -
12-46243559-G-T ARID2 c.1912G>T p.G638* Nonsense 14/21 -
8-134107393-G-C TG c.7345G>C p.E2449Q Missense 42/48 -
7-6043654-C-T PMS2 c.199G>A p.E67K Missense 3/15 -
1-11272865-A-G MTOR c.3386T>C p.L1129P Missense 22/58 -
11-108160401-A-T ATM c.4309A>T p.R1437* Nonsense 29/63 -
12-133256768-C-T POLE c.326G>A p.R109K Missense 4/49 -
13-22275530-G-T FGF9 c.583G>T p.D195Y Missense 3/3 -
14-45644709-A-G FANCM c.2752A>G p.K918E Missense 14/23 -
14-45644487-C-A FANCM c.2530C>A p.H844N Missense 14/23 -
13-22246086-G-T FGF9 c.35G>T p.G12V Missense 1/3 -
15-99459945-G-C IGF1R c.2041G>C p.E681Q Missense 10/21 -
19-52723071-T-G PPP2R1A c.1256T>G p.V419G Missense 10/15 -
7-6026609-T-G PMS2 c.1787A>C p.N596T Missense 11/15 -
1-11298102-G-T MTOR c.2006C>A p.P669H Missense 13/58 -
5-79968569-G-A MSH3 c.919G>A p.V307M Missense 6/24 -
8-48843268-T-G PRKDC c.1856A>C p.D619A Missense 17/87 -
10-43606840-C-A RET c.1449C>A p.Y483* Nonsense 7/20 -
12-133245299-T-G POLE c.1948A>C p.T650P Missense 18/49 -
X-66766437-C-A AR c.1449C>A p.Y483* Nonsense 1/8 -
1-11319466-T-C MTOR c.1A>G p.M1? Missense 2/58 -
11-94211936-T-G MRE11 c.509A>C p.Q170P Missense 6/20 -
11-9595997-A-C WEE1 c.517A>C p.T173P Missense 1/11 -
7-55214379-A-C EGFR c.505A>C p.S169R Missense 4/28 -
7-26192458-C-G NFE2L3 c.340C>G p.H114D Missense 1/4 -
7-26192600-G-C NFE2L3 c.482G>C p.R161P Missense 1/4 -
7-26192602-A-G NFE2L3 c.484A>G p.S162G Missense 1/4 -
7-26192604-T-G NFE2L3 c.486T>G p.S162R Missense 1/4 -
11-9595974-C-G WEE1 c.494C>G p.S165W Missense 1/11 -
2-16082703-G-C MYCN c.517G>C p.A173P Missense 2/3 -
2-29451822-A-C ALK c.2743T>G p.W915G Missense 16/29 -
5-176518696-A-G FGFR4 c.614A>G p.Q205R Missense 6/18 -
17-78867656-T-C RPTOR c.2392T>C p.S798P Missense 20/34 -
22-41573050-T-G EP300 c.5335T>G p.C1779G Missense 31/31 -
1-9770638-T-G PIK3CD c.125T>G p.L42R Missense 3/24 -
11-69633538-T-G FGF3 c.164A>C p.H55P Missense 1/3 -
2-39239442-T-G SOS1 c.2215A>C p.R739= Synonymous 14/23 -
1-11190714-T-G MTOR c.5485A>C p.T1829P Missense 39/58 -
1-11190723-T-G MTOR c.5476A>C p.T1826P Missense 39/58 -
1-9775737-C-G PIK3CD c.280C>G p.P94A Missense 4/24 -
1-27023190-A-G ARID1A c.296A>G p.D99G Missense 1/20 -
1-27023859-A-G ARID1A c.965A>G p.D322G Missense 1/20 -
2-29416434-A-G ALK c.4519T>C p.Y1507H Missense 29/29 -
16-89805070-A-G FANCA c.4307T>C p.L1436P Missense 43/43 -
1-150551979-T-G MCL1 c.28A>C p.I10L Missense 1/3 -
6-37138404-A-C PIM1 c.53A>C p.N18T Missense 1/6 -
6-37139088-T-G PIM1 c.428T>G p.L143R Missense 4/6 -
6-37140801-A-G PIM1 c.637A>G p.I213V Missense 5/6 -
1-11276243-T-G MTOR c.3079A>C p.I1027L Missense 20/58 -
6-37139238-T-A PIM1 c.578T>A p.L193H Missense 4/6 -
9-133710868-A-G ABL1 c.35A>G p.K12R Missense 1/11 -
12-133263877-G-C POLE c.25C>G p.R9G Missense 1/49 -
22-41564795-A-C EP300 c.4096A>C p.I1366L Missense 25/31 -
15-99250919-T-G IGF1R c.223T>G p.F75V Missense 2/21 -
8-6296548-A-C MCPH1 c.511A>C p.R171= Synonymous 6/14 -
4-1801242-G-C FGFR3 c.371G>C p.R124P Missense 3/18 -
16-89882986-T-G FANCA c.38A>C p.Q13P Missense 1/43 -
10-8097659-A-C GATA3 c.41A>C p.H14P Missense 2/6 -
10-8100274-A-G GATA3 c.248A>G p.Q83R Missense 3/6 -
14-45633702-G-T FANCM c.1722G>T p.M574I Missense 10/23 -
4-55972074-C-A KDR c.1570G>T p.V524L Missense 12/30 -
19-45867089-G-C ERCC2 c.1030C>G p.L344V Missense 11/23 -
10-8106008-A-C GATA3 c.831A>C p.R277= Synonymous 4/6 -
19-10600380-G-T KEAP1 c.1475C>A p.P492Q Missense 4/6 -
8-6338308-A-G MCPH1 c.2047A>G p.T683A Missense 11/14 -
13-25033417-A-G PARP4 c.2330T>C p.I777T Missense 19/34 -
10-43610051-C-A RET c.2003C>A p.P668H Missense 11/20 -
4-55976696-T-G KDR c.1129A>C p.I377L Missense 9/30 -
12-4481821-A-C FGF23 c.254T>G p.I85S Missense 2/3 -
12-133219243-G-A POLE c.4801C>T p.P1601S Missense 37/49 -
12-133219245-A-T POLE c.4799T>A p.I1600N Missense 37/49 -
19-4099319-T-G MAP2K2 c.799A>C p.I267L Missense 7/11 -
20-57485753-A-C GNAS c.1054A>C p.S352R Missense 13/13 -
14-45605739-A-C FANCM c.505A>C p.T169P Missense 1/23 -
3-178952007-A-C PIK3CA c.3062A>C p.Y1021S Missense 21/21 -
7-116340107-C-G MET c.969C>G p.S323R Missense 2/21 -
8-133899631-C-A TG c.2014C>A p.L672I Missense 9/48 -
5-1293925-C-T TERT c.1076G>A p.R359K Missense 2/16 -
19-4101084-A-C MAP2K2 c.638T>G p.F213C Missense 6/11 -
5-176520223-C-G FGFR4 c.1142C>G p.A381G Missense 9/18 -
19-4123829-T-G MAP2K2 c.44A>C p.N15T Missense 1/11 -
19-4117466-A-C MAP2K2 c.254T>G p.V85G Missense 2/11 -
5-1280281-C-A TERT c.1942G>T p.E648* Nonsense 4/16 -
12-133201347-C-G POLE c.6797G>C p.G2266A Missense 49/49 -
13-25020823-C-G PARP4 c.3362G>C p.G1121A Missense 27/34 -
17-29490365-TCAA-T NF1 c.450_452delCAA p.N151del InFrameDeletion 4/58 -
5-1293763-C-A TERT c.1238G>T p.C413F Missense 2/16 -
8-133899717-C-CCTGCTGCCGCTG TG c.2100_2101insCTGCTGCCGCTG p.N700_S701insLLPL InFrameInsertion 9/48 -
17-7579495-TGGG-T TP53 c.190_192delCCC p.P64del InFrameDeletion 4/11 -
6-35420353-G-T FANCE c.31G>T p.A11S Missense 1/10 -
1-11316116-A-C MTOR c.638T>G p.L213R Missense 5/58 -
4-72620717-G-C GC c.1142C>G p.S381* Nonsense 9/13 -
5-176520277-A-C FGFR4 c.1196A>C p.H399P Missense 9/18 -
4-72649692-T-G GC c.44A>C p.H15P Missense 1/13 -
3-52643849-T-C PBRM1 c.2047A>G p.I683V Missense 17/30 -
1-11298094-G-T MTOR c.2014C>A p.R672S Missense 13/58 -
X-70344227-A-C MED12 c.1963A>C p.S655R Missense 13/45 -
15-90628539-T-G IDH2 c.1048A>C p.T350P Missense 8/11 -
11-108115590-C-G ATM c.738C>G p.N246K Missense 7/63 -
5-176517995-G-A FGFR4 c.493G>A p.G165R Missense 5/18 -
11-108121598-G-T ATM c.1406G>T p.R469M Missense 10/63 -
11-108164080-A-G ATM c.4652A>G p.D1551G Missense 31/63 -
16-23641170-G-T PALB2 c.2305C>A p.L769I Missense 5/13 -
6-35427177-A-C FANCE c.1183A>C p.T395P Missense 6/10 -
X-48688195-A-C ERAS c.662A>C p.H221P Missense 2/2 -
5-79950667-A-G MSH3 c.121A>G p.T41A Missense 1/24 -
20-31024225-C-T ASXL1 c.3710C>T p.S1237F Missense 13/13 -
5-176522587-C-G FGFR4 c.1684C>G p.L562V Missense 13/18 -
19-4090676-C-A MAP2K2 c.1123G>T p.E375* Nonsense 11/11 -
X-115304250-G-T AGTR2 c.717G>T p.L239= Synonymous 3/3 -
7-140508773-G-T BRAF c.527C>A p.T176K Missense 4/18 -
7-140508761-C-G BRAF c.539G>C p.S180T Missense 4/18 -
3-52643545-T-C PBRM1 c.2351A>G p.N784S Missense 17/30 -
19-1220412-A-C STK11 c.505A>C p.S169R Missense 4/10 -
11-108175543-A-C ATM c.5638A>C p.T1880P Missense 37/63 -
11-69625440-A-C FGF3 c.353T>G p.V118G Missense 3/3 -
11-108129726-A-C ATM c.2390A>C p.K797T Missense 16/63 -
14-45606395-T-C FANCM c.632T>C p.L211S Missense 2/23 -
1-11190608-G-A MTOR c.5591C>T p.P1864L Missense 39/58 -
1-11291074-G-A MTOR c.2687C>T p.P896L Missense 18/58 -
3-138461512-T-G PIK3CB c.509A>C p.D170A Missense 5/24 -
1-11300417-T-G MTOR c.1729A>C p.S577R Missense 11/58 -
14-45628413-G-C FANCM c.1511G>C p.R504T Missense 9/23 -
16-2106768-A-C TSC2 c.772A>C p.K258Q Missense 8/42 -
16-2098657-A-C TSC2 c.41A>C p.K14T Missense 2/42 -
19-17954241-T-C JAK3 c.368A>G p.D123G Missense 4/24 -
16-89818625-C-T FANCA c.2987G>A p.R996K Missense 31/43 -
X-115303909-C-T AGTR2 c.376C>T p.L126= Synonymous 3/3 -
7-116414969-C-G MET c.3063C>G p.C1021W Missense 15/21 -
X-115304374-C-T AGTR2 c.841C>T p.L281= Synonymous 3/3 -
5-79970903-A-C MSH3 c.1129A>C p.N377H Missense 7/24 -
3-156395536-C-G TIPARP c.50C>G p.P17R Missense 2/6 -
3-156395508-C-G TIPARP c.22C>G p.P8A Missense 2/6 -
5-1294919-GTGC-G TERT c.184_186delGCA p.A62del InFrameDeletion 1/16 -
3-10115018-C-T FANCD2 c.2687C>T p.T896M Missense 28/44 -
11-9595989-A-C WEE1 c.509A>C p.H170P Missense 1/11 -
17-78867654-A-C RPTOR c.2390A>C p.N797T Missense 20/34 -
3-138417835-G-C PIK3CB c.1684C>G p.R562G Missense 13/24 -
14-45633709-A-C FANCM c.1729A>C p.T577P Missense 10/23 -
3-51982384-G-C PARP3 c.1511G>C p.G497A Missense 11/11 -
5-112154852-G-T APC c.1123G>T p.G375C Missense 10/16 -
12-133253978-T-G POLE c.772A>C p.T258P Missense 8/49 -
11-125503160-C-A CHEK1 c.527C>A p.P176Q Missense 6/13 -
17-78811768-A-C RPTOR c.1183A>C p.T395P Missense 10/34 -
19-17947952-C-T JAK3 c.1772G>A p.C591Y Missense 13/24 -
5-176517535-T-G FGFR4 c.236T>G p.V79G Missense 3/18 -
5-112174278-G-A APC c.2987G>A p.S996N Missense 16/16 -
19-1220446-G-C STK11 c.539G>C p.G180A Missense 4/10 -
3-156395862-C-T TIPARP c.376C>T p.P126S Missense 2/6 -
11-69518111-A-C FGF19 c.254T>G p.V85G Missense 2/3 -
8-48855894-G-A PRKDC c.841C>T p.Q281* Nonsense 10/87 -
15-91312406-A-G BLM c.2351A>G p.Y784C Missense 11/22 -
5-79950596-C-G MSH3 c.50C>G p.A17G Missense 1/24 -
1-27023174-C-G ARID1A c.280C>G p.P94A Missense 1/20 -
20-62839346-A-G MYT1 c.797A>G p.E266G Missense 7/23 -
20-62839532-T-G MYT1 c.983T>G p.L328R Missense 7/23 -
5-1293505-T-G TERT c.1496A>C p.K499T Missense 2/16 -
4-1801211-A-G FGFR3 c.340A>G p.T114A Missense 3/18 -
20-62853354-T-C MYT1 c.2350T>C p.F784L Missense 14/23 -
22-29099532-T-G CHEK2 c.869A>C p.N290T Missense 8/15 -
12-46230610-C-A ARID2 c.859C>A p.L287I Missense 8/21 -
11-69588132-T-A FGF4 c.566A>T p.K189M Missense 3/3 -
20-31019240-C-G ASXL1 c.835C>G p.H279D Missense 9/13 -
5-176519653-G-T FGFR4 c.925G>T p.D309Y Missense 8/18 -
13-28589340-G-T FLT3 c.2707C>A p.Q903K Missense 22/24 -
4-1808918-G-T FGFR3 c.2350G>T p.G784W Missense 18/18 -
X-53222664-C-A KDM5C c.4272G>T p.Q1424H Missense 25/26 -
20-31021635-G-C ASXL1 c.1634G>C p.R545P Missense 12/13 -
8-134144063-C-T TG c.7870C>T p.L2624= Synonymous 46/48 -
12-133218777-C-A POLE c.5159G>T p.G1720V Missense 38/49 -
13-28623637-C-A FLT3 c.920G>T p.R307I Missense 8/24 -
17-41244481-C-A BRCA1 c.3067G>T p.V1023L Missense 10/23 -
1-65332706-G-T JAK1 c.833C>A p.T278K Missense 7/25 -
8-133913643-G-T TG c.3479G>T p.R1160I Missense 16/48 -
X-53222978-G-T KDM5C c.4094C>A p.P1365Q Missense 24/26 -
3-52643547-G-T PBRM1 c.2349C>A p.H783Q Missense 17/30 -
X-70348541-G-T MED12 c.3448G>T p.A1150S Missense 24/45 -
8-133895170-G-T TG c.1001G>T p.G334V Missense 8/48 -
X-53245066-G-T KDM5C c.874C>A p.L292M Missense 7/26 -
8-48798613-C-A PRKDC c.4667G>T p.G1555G Missense 37/87 -
20-31023540-C-A ASXL1 c.3025C>A p.L1009I Missense 13/13 -
19-11098560-G-T SMARCA4 c.1078G>T p.G360C Missense 6/35 -
12-56488220-G-T ERBB3 c.1739G>T p.R580L Missense 15/28 -
1-27107063-C-G ARID1A c.6674C>G p.P2225R Missense 20/20 -
19-11095962-T-G SMARCA4 c.236T>G p.M79R Missense 3/35 -
5-176720961-G-T NSD1 c.6592G>T p.G2198W Missense 23/23 -
5-176524660-T-C FGFR4 c.2392T>C p.S798P Missense 18/18 -
16-89882365-G-T FANCA c.109C>A p.P37T Missense 2/43 -
15-90645561-C-G IDH2 c.62G>C p.W21S Missense 1/11 -
8-133899401-T-A TG c.1784T>A p.L595* Nonsense 9/48 -
3-142284990-T-C ATR c.265A>G p.S89G Missense 3/47 -
2-29497974-C-T ALK c.2032G>A p.D678N Missense 11/29 -
4-1807800-C-G FGFR3 c.1859C>G p.A620G Missense 14/18 -
4-1808278-C-A FGFR3 c.2036C>A p.S679Y Missense 16/18 -
1-45794991-C-T MUTYH c.1553G>A p.S518N Missense 16/16 -
15-99251013-T-G IGF1R c.317T>G p.I106S Missense 2/21 -
X-47424212-G-C ARAF c.217G>C p.A73P Missense 4/16 -
15-90630689-A-C IDH2 c.797T>G p.F266C Missense 6/11 -
5-176636646-A-G NSD1 c.1246A>G p.K416E Missense 5/23 -
15-99454633-AGG-CAT IGF1R c.1552_1554delAGGinsCAT p.R518H Missense 7/21 -
8-134144063-CTG-TTT TG c.7870_7872delCTGinsTTT p.L2624F Missense 46/48 -
13-28623857-T-C FLT3 c.797A>G p.E266G Missense 7/24 -
4-1801185-G-A FGFR3 c.314G>A p.G105E Missense 3/18 -
X-70339611-C-G MED12 c.280C>G p.P94A Missense 3/45 -
X-70342955-A-C MED12 c.1496A>C p.D499A Missense 11/45 -
1-226564966-A-T PARP1 c.1784T>A p.V595E Missense 13/23 -
7-26224319-G-T NFE2L3 c.1001G>T p.R334M Missense 4/4 -
20-30954248-C-A ASXL1 c.119C>A p.A40E Missense 2/13 -
12-46231362-G-C ARID2 c.1202G>C p.R401T Missense 10/21 -
2-29497970-G-T ALK c.2036C>A p.P679H Missense 11/29 -
1-65303688-C-A JAK1 c.3067G>T p.G1023C Missense 22/25 -
13-28623785-T-G FLT3 c.869A>C p.K290T Missense 7/24 -
19-10610393-A-C KEAP1 c.317T>G p.V106G Missense 2/6 -
20-62853353-C-A MYT1 c.2349C>A p.N783K Missense 14/23 -
19-4099244-G-T MAP2K2 c.874C>A p.H292N Missense 7/11 -
13-25029206-G-T PARP4 c.2707C>A p.L903M Missense 22/34 -
5-176638145-A-C NSD1 c.2745A>C p.K915N Missense 5/23 -
12-133242006-C-A POLE c.2350G>T p.E784* Nonsense 21/49 -
12-133219467-C-A POLE c.4667G>T p.R1556L Missense 36/49 -
8-133909917-C-A TG c.3025C>A p.R1009S Missense 12/48 -
X-53246338-C-A KDM5C c.644G>T p.R215I Missense 5/26 -
12-56481913-C-T ERBB3 c.841C>T p.Q281* Nonsense 7/28 -
5-112174076-C-T APC c.2785C>T p.H929Y Missense 16/16 -
X-76938560-C-T ATRX c.2188G>A p.D730N Missense 9/35 -
5-112179300-G-A APC c.8009G>A p.R2670K Missense 16/16 -
5-112177392-C-T APC c.6101C>T p.S2034F Missense 16/16 -
17-29483097-T-C NF1 c.157T>C p.L53= Synonymous 2/58 -
4-1803746-G-T FGFR3 c.924G>T p.V308= Synonymous 7/18 -
X-53243927-G-A KDM5C c.1066C>T p.P356S Missense 8/26 -
9-135797258-C-G TSC1 c.611G>C p.R204P Missense 7/23 -
17-29685611-C-A NF1 c.8084C>A p.P2695Q Missense 55/58 -
17-29562777-C-A NF1 c.3857C>A p.T1286K Missense 28/58 -
13-32893449-C-A BRCA2 c.303C>A p.F101L Missense 3/27 -
3-142281724-C-A ATR c.520G>T p.V174F Missense 4/47 -
7-55220332-C-T EGFR c.722C>T p.T241I Missense 6/28 -
8-128750932-G-T MYC c.469G>T p.A157S Missense 2/3 -
3-142285057-C-A ATR c.198G>T p.V66= Synonymous 3/47 -
5-79968636-A-G MSH3 c.986A>G p.K329R Missense 6/24 -
4-1801034-G-A FGFR3 c.163G>A p.D55N Missense 3/18 -
3-142254991-C-A ATR c.3778G>T p.E1260* Nonsense 20/47 -
3-142188409-C-A ATR c.6322G>T p.G2108C Missense 38/47 -
X-53239891-T-G KDM5C c.1550A>C p.D517A Missense 11/26 -
X-70340948-G-T MED12 c.681G>T p.E227D Missense 5/45 -
8-128751207-C-A MYC c.744C>A p.G248= Synonymous 2/3 -
12-56487640-C-A ERBB3 c.1573C>A p.R525= Synonymous 13/28 -
X-53225999-C-A KDM5C c.2850G>T p.M950I Missense 19/26 -
15-99442714-G-A IGF1R c.1111G>A p.A371T Missense 5/21 -
7-55268014-A-G EGFR c.2854A>G p.M952V Missense 24/28 -
2-29455170-C-T ALK c.2632G>A p.G878S Missense 15/29 -
5-79950575-G-T MSH3 c.29G>T p.G10V Missense 1/24 -
5-80149953-G-T MSH3 c.2818G>T p.G940C Missense 21/24 -
1-65303659-C-A JAK1 c.3096G>T p.K1032N Missense 22/25 -
2-29606654-C-A ALK c.1226G>T p.S409I Missense 5/29 -
20-62839453-G-T MYT1 c.904G>T p.E302* Nonsense 7/23 -
20-62842607-G-T MYT1 c.1340G>T p.C447F Missense 8/23 -
15-99434591-G-T IGF1R c.678G>T p.E226D Missense 3/21 -
16-23647151-C-A PALB2 c.716G>T p.R239I Missense 4/13 -
19-10610685-C-A KEAP1 c.25G>T p.G9W Missense 2/6 -
19-45917000-G-A ERCC1 c.778C>T p.L260= Synonymous 9/10 -
12-1042190-C-T RAD52 c.35G>A p.R12H Missense 2/12 -
5-56111785-G-T MAP3K1 c.385G>T p.A129S Missense 1/20 -
5-79950696-CGCTGCAGCGGCTGCAGCG-C MSH3 c.153_170del18 p.A57_A62del InFrameDeletion 1/24 -
1-65348992-TCTG-T JAK1 c.170_172delCAG p.A57del InFrameDeletion 3/25 -
19-10602467-C-T KEAP1 c.1111G>A p.G371S Missense 3/6 -
1-65304261-T-C JAK1 c.2854A>G p.I952V Missense 21/25 -
X-76920220-G-T ATRX c.3857C>A p.S1286Y Missense 11/35 -
15-99467763-G-A IGF1R c.2632G>A p.E878K Missense 13/21 -
9-135797349-C-A TSC1 c.520G>T p.E174* Nonsense 7/23 -
15-66777356-C-T MAP2K1 c.722C>T p.S241F Missense 7/11 -
16-23632700-C-A PALB2 c.3096G>T p.M1032I Missense 10/13 -
3-142281775-C-A ATR c.469G>T p.V157F Missense 4/47 -
X-70342174-G-T MED12 c.1226G>T p.G409V Missense 8/45 -
12-133253137-C-A POLE c.904G>T p.G302C Missense 9/49 -
8-128750661-G-T MYC c.198G>T p.K66N Missense 2/3 -
19-10600515-C-A KEAP1 c.1340G>T p.R447L Missense 4/6 -
21-30699131-A-G BACH1 c.986A>G p.Y329C Missense 3/5 -
7-55220288-G-T EGFR c.678G>T p.K226N Missense 6/28 -
19-1220698-G-T STK11 c.716G>T p.W239L Missense 5/10 -
12-133226280-C-A POLE c.3778G>T p.A1260S Missense 30/49 -
X-70341631-C-T MED12 c.1066C>T p.R356W Missense 7/45 -
5-56155686-C-T MAP3K1 c.778C>T p.R260C Missense 3/20 -
X-76829719-C-A ATRX c.6322G>T p.V2108L Missense 28/35 -
8-48868457-G-A PRKDC c.376C>T p.P126S Missense 4/87 -
7-26192503-G-T NFE2L3 c.385G>T p.G129C Missense 1/4 -
5-131923338-C-T RAD50 c.841C>T p.Q281* Nonsense 6/25 -
8-48866220-C-A PRKDC c.681G>T p.L227F Missense 7/87 -
5-79961177-C-T MSH3 c.574C>T p.Q192* Nonsense 3/24 -
12-133254006-G-T POLE c.744C>A p.Y248* Nonsense 8/49 -
12-133238127-C-A POLE c.2850G>T p.K950N Missense 24/49 -
7-55240749-G-A EGFR c.1993G>A p.G665S Missense 17/28 -
1-27058069-T-G ARID1A c.1777T>G p.S593A Missense 3/20 -
7-81355333-C-A HGF c.1041G>T p.K347N Missense 9/18 -
11-108123580-G-T ATM c.1839G>T p.V613= Synonymous 12/63 -
5-176517612-G-T FGFR4 c.313G>T p.G105C Missense 3/18 -
2-190742129-T-A PMS1 c.2766T>A p.F922L Missense 13/13 -
7-55220273-G-T EGFR c.663G>T p.G221= Synonymous 6/28 -
2-215645783-A-C BARD1 c.815T>G p.F272C Missense 4/11 -
17-7576893-G-T TP53 c.953C>A p.P318Q Missense 9/11 -
17-33445576-A-C RAD51D c.207T>G p.A69= Synonymous 3/10 -
12-133218333-C-A POLE c.5278G>T p.V1760L Missense 39/49 -
4-55968660-G-T KDR c.2003C>A p.T668K Missense 14/30 -
15-99465505-T-C IGF1R c.2330T>C p.F777S Missense 11/21 -
17-37872154-C-A ERBB2 c.1475C>A p.A492D Missense 12/27 -
1-11319439-T-G MTOR c.28A>C p.T10P Missense 2/58 -
22-50354812-T-G PIM3 c.125T>G p.V42G Missense 2/6 -
2-30142862-T-G ALK c.664A>C p.T222P Missense 1/29 -
12-133250264-A-C POLE c.1256T>G p.V419G Missense 13/49 -
16-89874720-A-T FANCA c.578T>A p.L193Q Missense 6/43 -
12-133263867-T-C POLE c.35A>G p.D12G Missense 1/49 -
19-10610474-A-C KEAP1 c.236T>G p.V79G Missense 2/6 -
15-90634833-C-G IDH2 c.159G>C p.M53I Missense 2/11 -
12-4479844-C-G FGF23 c.421G>C p.A141P Missense 3/3 -
17-37866648-T-G ERBB2 c.815T>G p.V272G Missense 7/27 -
1-27023403-A-C ARID1A c.509A>C p.H170P Missense 1/20 -
17-37872610-G-T ERBB2 c.1570G>T p.G524W Missense 13/27 -
1-11294316-T-G MTOR c.2215A>C p.T739P Missense 14/58 -
1-27023388-C-G ARID1A c.494C>G p.A165G Missense 1/20 -
2-29448415-C-G ALK c.3084G>C p.E1028D Missense 19/29 -
1-9775621-A-C PIK3CD c.164A>C p.Y55S Missense 4/24 -
12-4479754-T-G FGF23 c.511A>C p.T171P Missense 3/3 -
7-26192456-T-G NFE2L3 c.338T>G p.V113G Missense 1/4 -
4-1801505-GG-AT FGFR3 c.411_412delinsAT p.E138* Missense 4/18 -
10-43608374-G-T RET c.1722G>T p.E574D Missense 9/20 -
11-94192599-G-A MRE11 c.1475C>T p.A492V Missense 13/20 -
2-213403205-G-C ERBB4 c.50C>G p.A17G Missense 1/28 -
5-112174464-A-G APC c.3173A>G p.D1058G Missense 16/16 -
20-30253851-G-C BCL2L1 c.603C>G p.A201= Synonymous 3/3 -
12-46243376-A-C ARID2 c.1729A>C p.N577H Missense 14/21 -
7-116339163-C-G MET c.25C>G p.P9A Missense 2/21 -
6-37138790-T-G PIM1 c.223T>G p.S75A Missense 3/6 -
12-46243953-A-G ARID2 c.2047A>G p.R683G Missense 15/21 -
6-152201799-A-T ESR1 c.653A>T p.D218V Missense 3/8 -
19-1206928-C-T STK11 c.16C>T p.P6S Missense 1/10 -
21-39775512-T-C ERG c.508A>G p.K170E Missense 4/10 -
X-14883034-G-C FANCB c.599C>G p.P200R Missense 3/10 -
2-47690262-G-T MSH2 c.1479G>T p.Q493H Missense 9/16 -
19-4123811-C-A MAP2K2 c.62G>T p.G21V Missense 1/11 -
5-79952314-G-T MSH3 c.322G>T p.E108* Nonsense 2/24 -
8-133885427-C-G TG c.599C>G p.T200R Missense 5/48 -
11-9595530-C-G WEE1 c.50C>G p.A17G Missense 1/11 -
10-8100629-C-G GATA3 c.603C>G p.S201= Synonymous 3/6 -
10-123324017-CTTG-C FGFR2 c.450_452delCAA p.N150del InFrameDeletion 4/18 -
19-4097292-G-C MAP2K2 c.969C>G p.D323E Missense 8/11 -
12-133248866-T-G POLE c.1729A>C p.T577P Missense 16/49 -
13-25068790-T-G PARP4 c.662A>C p.E221A Missense 7/34 -
11-108098551-A-G ATM c.121A>G p.K41E Missense 3/63 -
17-29557897-G-T NF1 c.3151G>T p.G1051* Nonsense 24/58 -
3-41266884-A-C CTNNB1 c.555A>C p.R185S Missense 5/15 -
11-108098379-A-C ATM c.28A>C p.I10L Missense 2/63 -
15-99465603-G-T IGF1R c.2428G>T p.A810S Missense 11/21 -
5-176522360-C-T FGFR4 c.1549C>T p.L517= Synonymous 12/18 -
17-29496971-A-C NF1 c.542A>C p.Q181P Missense 5/58 -
2-16082844-G-T MYCN c.658G>T p.A220S Missense 2/3 -
17-29528121-A-C NF1 c.1129A>C p.I377L Missense 10/58 -
17-29483127-A-C NF1 c.187A>C p.K63Q Missense 2/58 -
17-78704484-T-G RPTOR c.632T>G p.L211R Missense 5/34 -
17-78820295-A-C RPTOR c.1235A>C p.Q412P Missense 11/34 -
13-25051937-A-C PARP4 c.1691T>G p.F564C Missense 14/34 -
20-62848481-G-C MYT1 c.1693G>C p.A565P Missense 11/23 -
14-45605466-T-C FANCM c.232T>C p.S78P Missense 1/23 -
20-31017767-T-G ASXL1 c.629T>G p.L210R Missense 8/13 -
X-70340014-T-G MED12 c.547T>G p.F183V Missense 4/45 -
14-45644896-A-C FANCM c.2939A>C p.H980P Missense 14/23 -
20-31021184-A-C ASXL1 c.1183A>C p.I395L Missense 12/13 -
11-108183154-G-T ATM c.5935G>T p.E1979* Nonsense 40/63 -
8-133919008-C-T TG c.3710C>T p.P1237L Missense 17/48 -
19-17954605-C-T JAK3 c.289G>A p.V97I Missense 3/24 -
X-48688073-C-A ERAS c.540C>A p.T180= Synonymous 2/2 -
15-43748531-A-G TP53BP1 c.2275T>C p.S759P Missense 12/28 -
3-169099309-T-G MECOM c.41A>C p.N14T Missense 2/17 -
5-80021367-A-G MSH3 c.1436A>G p.D479G Missense 9/24 -
5-79950736-CCCA-C MSH3 c.190_192delCCA p.P64del InFrameDeletion 1/24 -
8-133880458-G-T TG c.166G>T p.G56C Missense 2/48 -
3-41277222-T-G CTNNB1 c.1691T>G p.V564G Missense 11/15 -
3-41275069-A-C CTNNB1 c.1235A>C p.D412A Missense 9/15 -
11-108124605-A-C ATM c.1963A>C p.T655P Missense 13/63 -
11-108141995-A-C ATM c.2939A>C p.Y980S Missense 20/63 -
X-48687822-G-A ERAS c.289G>A p.A97T Missense 2/2 -
15-99478247-G-T IGF1R c.3151G>T p.A1051S Missense 16/21 -
17-37863356-A-C ERBB2 c.187A>C p.T63P Missense 2/27 -
6-35423815-C-A FANCE c.540C>A p.S180= Synonymous 2/10 -
X-70345891-G-T MED12 c.2428G>T p.E810* Nonsense 18/45 -
17-29527603-T-C NF1 c.1052T>C p.V351A Missense 9/58 -
2-16082728-A-C MYCN c.542A>C p.H181P Missense 2/3 -
14-104165767-CT-TA XRCC3 c.707_708delinsTA p.Q236L Missense 8/10 -
8-133885375-T-G TG c.547T>G p.C183G Missense 5/48 -
22-29092912-G-C CHEK2 c.1072C>G p.Q358E Missense 10/15 -
20-31021427-C-T ASXL1 c.1426C>T p.L476= Synonymous 12/13 -
17-41247935-C-T BRCA1 c.598G>A p.G200R Missense 9/23 -
4-1807790-G-T FGFR3 c.1849G>T p.D617Y Missense 14/18 -
9-5022021-G-T JAK2 c.34G>T p.E12* Nonsense 3/25 -
3-52437888-T-C BAP1 c.1273A>G p.K425E Missense 13/17 -
17-41245042-C-G BRCA1 c.2506G>C p.E836Q Missense 10/23 -
2-42509974-G-A EML4 c.803G>A p.R268Q Missense 8/23 -
1-27023724-G-T ARID1A c.830G>T p.G277V Missense 1/20 -
1-150551814-G-C MCL1 c.193C>G p.P65A Missense 1/3 -
8-38277206-T-G FGFR1 c.1129A>C p.I377L Missense 9/18 -
8-38287353-C-A FGFR1 c.205G>T p.D69Y Missense 3/18 -
7-140476713-C-G BRAF c.1693G>C p.D565H Missense 13/18 -
7-6043420-A-C PMS2 c.254T>G p.L85R Missense 4/15 -
5-176522348-G-T FGFR4 c.1537G>T p.D513Y Missense 12/18 -
1-45798772-C-A MUTYH c.375G>T p.M125I Missense 5/16 -
5-176524535-A-G FGFR4 c.2267A>G p.D756G Missense 18/18 -
9-5072493-A-AT JAK2 c.1644_1644dupT p.E549* Nonsense 13/25 -
3-142215948-T-TTGGGGGGGG ATR c.5644_5645insCCCCCCCCA p.L1881_N1882insTPP InFrameInsertion 33/47 -
2-42508076-A-C EML4 c.754A>C p.T252P Missense 7/23 -
5-112162933-G-T APC c.1537G>T p.V513L Missense 12/16 -
7-140482952-T-G BRAF c.1183A>C p.T395P Missense 10/18 -
15-89836270-A-G FANCI c.2267A>G p.Y756C Missense 22/38 -
17-63554141-C-T AXIN2 c.598G>A p.V200M Missense 2/11 -
2-190660534-G-T PMS1 c.172G>T p.G58W Missense 3/13 -
1-243800995-C-A AKT3 c.479G>T p.G160V Missense 6/14 -
5-1280427-C-A TERT c.1796G>T p.R599L Missense 4/16 -
13-48955489-T-G RB1 c.1605T>G p.F535L Missense 17/27 -
14-45658096-G-T FANCM c.4871G>T p.C1624F Missense 20/23 -
5-1268699-G-A TERT c.2518C>T p.L840= Synonymous 9/16 -
5-1294284-C-A TERT c.717G>T p.R239S Missense 2/16 -
14-45639813-A-G FANCM c.2024A>G p.K675R Missense 12/23 -
13-49039366-A-G RB1 c.2351A>G p.H784R Missense 23/27 -
6-87796071-A-T CGA c.170T>A p.F57Y Missense 3/4 -
19-4101090-C-A MAP2K2 c.632G>T p.C211F Missense 6/11 -
3-138403488-C-A PIK3CB c.2294G>T p.C765F Missense 17/24 -
13-28588591-C-T FLT3 c.2857G>A p.A953T Missense 23/24 -
7-55224255-A-G EGFR c.1036A>G p.K346E Missense 9/28 -
12-133249224-G-A POLE c.1675C>T p.R559W Missense 15/49 -
3-30713528-G-A TGFBR2 c.853G>A p.A285T Missense 4/7 -
1-11319433-C-A MTOR c.34G>T p.A12S Missense 2/58 -
20-31020697-G-T ASXL1 c.994G>T p.E332* Nonsense 11/13 -
20-31023999-G-T ASXL1 c.3484G>T p.V1162F Missense 13/13 -
6-87796032-G-A CGA c.209C>T p.T70M Missense 3/4 -
19-11094965-C-G SMARCA4 c.138C>G p.S46R Missense 2/35 -
2-47637344-C-A MSH2 c.478C>A p.Q160K Missense 3/16 -
22-41527514-G-T EP300 c.1405G>T p.A469S Missense 6/31 -
12-25380211-C-A KRAS c.247G>T p.A83S Missense 3/5 -
2-47657056-A-G MSH2 c.1252A>G p.I418V Missense 7/16 -
6-87796008-G-T CGA c.233C>A p.T78N Missense 3/4 -
19-10610706-G-A KEAP1 c.4C>T p.Q2* Nonsense 2/6 -
19-10610237-C-A KEAP1 c.473G>T p.G158V Missense 2/6 -
17-7577088-TGCGCCG-T TP53 c.844_849delCGGCGC p.R282_R283del InFrameDeletion 8/11 -
6-87796067-A-AGGGGCGGCG CGA c.173_174insCGCCGCCCC p.S58_R59insAAP InFrameInsertion 3/4 -
17-78914338-CGG-TGT RPTOR c.2962_2964delCGGinsTGT p.R988C Missense 25/34 -
9-135802627-ATGC-A TSC1 c.169_171delGCA p.A57del InFrameDeletion 4/23 -
6-87796047-AGTG-A CGA c.191_193delCAC p.P64del InFrameDeletion 3/4 -
12-133257231-C-A POLE c.247G>T p.D83Y Missense 3/49 -
5-1294896-G-A TERT c.209C>T p.S70F Missense 1/16 -
10-30727974-G-T MAP3K8 c.107G>T p.S36I Missense 3/9 -
X-115304569-A-G AGTR2 c.1036A>G p.S346G Missense 3/3 -
7-140439672-C-A BRAF c.2067G>T p.M689I Missense 17/18 -
7-140501241-T-G BRAF c.831A>C p.P277= Synonymous 6/18 -
22-29083964-C-T CHEK2 c.1553G>A p.S518N Missense 15/15 -
17-41243779-C-G BRCA1 c.3769G>C p.E1257Q Missense 10/23 -
20-31021157-T-C ASXL1 c.1156T>C p.L386= Synonymous 12/13 -
17-56772369-T-G RAD51C c.223T>G p.Y75D Missense 2/9 -
7-6029444-C-A PMS2 c.1131G>T p.L377= Synonymous 10/15 -
7-6026999-C-A PMS2 c.1397G>T p.G466V Missense 11/15 -
2-29451762-C-T ALK c.2803G>A p.G935R Missense 16/29 -
2-29917826-T-A ALK c.842A>T p.H281L Missense 3/29 -
13-113887579-G-T CUL4A c.601G>T p.E201* Nonsense 6/20 -
5-176523738-G-A FGFR4 c.2149G>A p.E717K Missense 16/18 -
7-140482907-G-T BRAF c.1228C>A p.L410I Missense 10/18 -
7-140501313-C-A BRAF c.759G>T p.K253N Missense 6/18 -
2-42515367-G-A EML4 c.1123G>A p.D375N Missense 11/23 -
8-38287246-G-T FGFR1 c.312C>A p.S104R Missense 3/18 -
15-89820102-A-G FANCI c.1273A>G p.I425V Missense 13/38 -
3-52437468-C-G BAP1 c.1693G>C p.A565P Missense 13/17 -
3-142255000-C-G ATR c.3769G>C p.D1257H Missense 20/47 -
4-1805560-C-G FGFR3 c.1072C>G p.P358A Missense 8/18 -
5-131940660-C-T RAD50 c.2687C>T p.T896I Missense 16/25 -
2-42557204-G-A EML4 c.2803G>A p.E935K Missense 23/23 -
19-17943502-C-G JAK3 c.2506G>C p.V836L Missense 19/24 -
2-29446262-G-A ALK c.3305C>T p.T1102I Missense 20/29 -
17-56774181-C-T RAD51C c.532C>T p.Q178* Nonsense 3/9 -
7-55241701-G-A EGFR c.2149G>A p.V717M Missense 18/28 -
5-131911485-A-C RAD50 c.230A>C p.D77A Missense 3/25 -
17-41246392-A-G BRCA1 c.1156T>C p.F386L Missense 10/23 -
13-48923153-G-T RB1 c.601G>T p.A201S Missense 6/27 -
20-31021124-G-A ASXL1 c.1123G>A p.V375M Missense 12/13 -
3-10076170-T-G FANCD2 c.223T>G p.F75V Missense 4/44 -
7-116339308-T-A MET c.170T>A p.L57Q Missense 2/21 -
7-55273056-G-T EGFR c.3379G>T p.D1127Y Missense 28/28 -
1-11307998-C-A MTOR c.994G>T p.G332W Missense 7/58 -
3-138456718-C-A PIK3CB c.632G>T p.S211I Missense 6/24 -
1-11319329-G-C MTOR c.138C>G p.H46Q Missense 2/58 -
12-1040400-C-A RAD52 c.172G>T p.G58C Missense 3/12 -
19-4090622-C-T MAP2K2 c.1177G>A p.G393S Missense 11/11 -
2-47630468-C-T MSH2 c.138C>T p.H46= Synonymous 1/16 -
8-133879279-G-T TG c.34G>T p.A12S Missense 1/48 -
8-48869976-AA-TG PRKDC c.169_170delTTinsCA p.L57Q Missense 2/87 -
8-48839898-C-T PRKDC c.2275G>A p.G759S Missense 21/87 -
19-52725370-G-T PPP2R1A c.1537G>T p.G513W Missense 13/15 -
13-49039189-A-G RB1 c.2267A>G p.Y756C Missense 22/27 -
17-63554705-C-A AXIN2 c.34G>T p.D12Y Missense 2/11 -
17-78896566-T-C RPTOR c.2563T>C p.S855P Missense 22/34 -
17-78617597-A-C RPTOR c.335A>C p.N112T Missense 3/34 -
13-48937004-A-C RB1 c.772A>C p.N258H Missense 8/27 -
1-45799126-A-C MUTYH c.223T>G p.W75G Missense 3/16 -
8-48849008-T-G PRKDC c.1183A>C p.M395L Missense 12/87 -
14-45623972-T-G FANCM c.1256T>G p.M419R Missense 7/23 -
2-48026609-G-A MSH6 c.1487G>A p.C496Y Missense 4/10 -
5-79961015-A-G MSH3 c.412A>G p.K138E Missense 3/24 -
17-41246857-T-G BRCA1 c.691A>C p.T231P Missense 10/23 -
22-29130559-G-C CHEK2 c.151C>G p.Q51E Missense 2/15 -
6-152129382-A-C ESR1 c.335A>C p.H112P Missense 1/8 -
4-1801523-C-G FGFR3 c.429C>G p.D143E Missense 4/18 -
19-10597483-C-A KEAP1 c.1720G>T p.G574C Missense 6/6 -
16-89836306-G-T FANCA c.2443C>A p.P815T Missense 26/43 -
1-243800930-C-A AKT3 c.544G>T p.E182* Nonsense 6/14 -
17-78727833-C-A RPTOR c.678C>A p.H226Q Missense 6/34 -
4-1806083-G-C FGFR3 c.1102G>C p.E368Q Missense 9/18 -
13-25067841-T-G PARP4 c.772A>C p.T258P Missense 8/34 -
10-43595999-C-T RET c.166C>T p.L56= Synonymous 2/20 -
19-1219323-G-T STK11 c.375G>T p.M125I Missense 3/10 -
17-59937249-C-A BRIP1 c.113G>T p.S38I Missense 3/20 -
17-78681705-G-T RPTOR c.413G>T p.R138L Missense 4/34 -
12-25380292-G-T KRAS c.166C>A p.L56I Missense 3/5 -
5-80021309-A-G MSH3 c.1378A>G p.N460D Missense 9/24 -
10-43607573-C-T RET c.1549C>T p.L517= Synonymous 8/20 -
19-10610528-T-A KEAP1 c.182A>T p.K61M Missense 2/6 -
11-532697-T-G HRAS c.509A>C p.K170T Missense 5/6 -
11-9595909-C-G WEE1 c.429C>G p.C143W Missense 1/11 -
7-81372695-C-A HGF c.839G>T p.W280L Missense 7/18 -
5-79961121-G-A MSH3 c.518G>A p.S173N Missense 3/24 -
10-43595984-C-G RET c.151C>G p.L51V Missense 2/20 -
1-11301633-C-A MTOR c.1518G>T p.E506D Missense 10/58 -
18-39573301-C-T PIK3C3 c.782C>T p.S261F Missense 7/25 -
17-63533825-C-A AXIN2 c.1329G>T p.L443= Synonymous 6/11 -
13-25044131-A-C PARP4 c.1947T>G p.S649R Missense 16/34 -
8-38275847-C-A FGFR1 c.1329G>T p.L443= Synonymous 10/18 -
2-48026476-A-G MSH6 c.1354A>G p.M452V Missense 4/10 -
13-32906577-A-C BRCA2 c.962A>C p.Q321P Missense 10/27 -
17-29554259-G-A NF1 c.2275G>A p.V759M Missense 19/58 -
12-133237738-G-T POLE c.2877C>A p.F959L Missense 25/49 -
12-133249381-C-A POLE c.1518G>T p.M506I Missense 15/49 -
1-45795007-C-A MUTYH c.1537G>T p.A513S Missense 16/16 -
5-170819773-A-G NPM1 c.412A>G p.I138V Missense 5/11 -
17-62007135-C-A CD79B c.544G>T p.D182Y Missense 4/6 -
2-48027565-C-A MSH6 c.2443C>A p.L815I Missense 4/10 -
16-89882304-A-T FANCA c.170T>A p.L57Q Missense 2/43 -
2-48026251-A-C MSH6 c.1129A>C p.K377Q Missense 4/10 -
17-7576884-T-G TP53 c.962A>C p.K321T Missense 9/11 -
2-48027999-C-A MSH6 c.2877C>A p.R959= Synonymous 4/10 -
12-133248902-C-G POLE c.1693G>C p.A565P Missense 16/49 -
2-48027069-T-G MSH6 c.1947T>G p.D649E Missense 4/10 -
11-108122676-G-T ATM c.1720G>T p.E574* Nonsense 11/63 -
5-80021285-A-G MSH3 c.1354A>G p.R452G Missense 9/24 -
12-133218925-G-A POLE c.5011C>T p.L1671F Missense 38/49 -
13-25026596-G-A PARP4 c.2962C>T p.Q988* Nonsense 24/34 -
7-152346361-G-A XRCC2 c.209C>T p.S70L Missense 3/3 -
8-133894724-G-T TG c.756G>T p.L252F Missense 7/48 -
5-112177972-C-A APC c.6681C>A p.G2227= Synonymous 16/16 -
15-43772135-C-T TP53BP1 c.580G>A p.E194K Missense 6/28 -
3-37055924-G-C MLH1 c.679G>C p.E227Q Missense 9/19 -
19-10610534-T-G KEAP1 c.176A>C p.H59P Missense 2/6 -
8-90967612-T-A NBN c.1296A>T p.S432= Synonymous 10/16 -
7-55211109-G-C EGFR c.352G>C p.A118P Missense 3/28 -
2-29754925-C-A ALK c.1010G>T p.W337L Missense 4/29 -
7-55211061-G-T EGFR c.304G>T p.E102* Nonsense 3/28 -
8-133880393-G-T TG c.101G>T p.C34F Missense 2/48 -
4-72631347-G-A GC c.275C>T p.S92F Missense 4/13 -
X-70343507-C-T MED12 c.1681C>T p.P561S Missense 12/45 -
15-43762077-TGGGATA-T TP53BP1 c.1362_1367delTATCCC p.I455_P456del InFrameDeletion 11/28 -
15-90631961-ATCT-A IDH2 c.389_391delAGA p.K130del InFrameDeletion 4/11 -
15-43762077-ATGG-A TP53BP1 c.1366_1368delCCA p.P456del InFrameDeletion 11/28 -
20-62836925-GGCC-G MYT1 c.169_171delGCC p.A57del InFrameDeletion 6/23 -
5-79950751-CCCG-C MSH3 c.208_210delGCC p.A70del InFrameDeletion 1/24 -
7-26225095-C-T NFE2L3 c.1777C>T p.Q593* Nonsense 4/4 -
12-133257827-C-A POLE c.101G>T p.R34L Missense 2/49 -
12-133212528-T-C POLE c.5761A>G p.N1921D Missense 42/49 -
7-26224715-G-C NFE2L3 c.1397G>C p.G466A Missense 4/4 -
7-148515133-C-A EZH2 c.1076G>T p.R359I Missense 10/20 -
5-112170861-A-T APC c.1957A>T p.R653W Missense 15/16 -
19-11096030-G-T SMARCA4 c.304G>T p.G102C Missense 3/35 -
7-26192591-G-T NFE2L3 c.473G>T p.R158L Missense 1/4 -
1-65332842-T-A JAK1 c.697A>T p.N233Y Missense 7/25 -
7-116397809-A-G MET c.2083A>G p.K695E Missense 8/21 -
X-76855226-T-C ATRX c.5761A>G p.S1921G Missense 24/35 -
17-7579461-C-G TP53 c.226G>C p.A76P Missense 4/11 -
7-116397773-A-G MET c.2047A>G p.N683D Missense 8/21 -
X-76776957-C-A ATRX c.6995G>T p.R2332I Missense 33/35 -
19-1218459-C-A STK11 c.334C>A p.Q112K Missense 2/10 -
7-22766891-T-G IL6 c.10T>G p.F4V Missense 1/5 -
7-26217689-A-T NFE2L3 c.697A>T p.I233L Missense 2/4 -
8-133899014-G-C TG c.1397G>C p.R466T Missense 9/48 -
19-10602692-G-C KEAP1 c.886C>G p.R296G Missense 3/6 -
15-43748849-T-A TP53BP1 c.1957A>T p.M653L Missense 12/28 -
8-133898893-G-T TG c.1276G>T p.V426L Missense 9/48 -
8-133920527-A-G TG c.3944A>G p.Q1315R Missense 18/48 -
3-142281082-C-T ATR c.1162G>A p.D388N Missense 4/47 -
3-142281814-C-G ATR c.430G>C p.V144L Missense 4/47 -
8-90995015-C-A NBN c.106G>T p.E36* Nonsense 2/16 -
8-133885448-T-A TG c.620T>A p.L207Q Missense 5/48 -
5-1294130-C-T TERT c.871G>A p.G291S Missense 2/16 -
X-70356398-G-T MED12 c.5293G>T p.E1765* Nonsense 37/45 -
3-52623259-C-G PBRM1 c.2792G>C p.S931T Missense 19/30 -
9-80537117-A-G GNAQ c.281T>C p.M94T Missense 2/7 -
7-26217572-G-A NFE2L3 c.580G>A p.V194I Missense 2/4 -
17-37619117-A-C CDK12 c.793A>C p.S265R Missense 1/14 -
1-65325846-C-A JAK1 c.1276G>T p.D426Y Missense 9/25 -
3-142281624-A-T ATR c.620T>A p.V207D Missense 4/47 -
14-20813220-A-C PARP2 c.176A>C p.K59T Missense 2/16 -
10-89720720-G-A PTEN c.871G>A p.E291K Missense 8/9 -
8-133905965-G-C TG c.2792G>C p.R931P Missense 11/48 -
21-39795439-A-G ERG c.281T>C p.V94A Missense 3/10 -
11-69589519-G-T FGF4 c.334C>A p.R112S Missense 1/3 -
1-27057973-C-T ARID1A c.1681C>T p.Q561* Nonsense 3/20 -
17-29664875-C-A NF1 c.6681C>A p.D2227E Missense 44/58 -
4-106155617-G-A TET2 c.518G>A p.G173E Missense 3/11 -
4-106155281-A-T TET2 c.182A>T p.Y61F Missense 3/11 -
5-79974881-G-C MSH3 c.1309G>C p.E437Q Missense 8/24 -
7-81381575-A-C HGF c.486T>G p.F162L Missense 5/18 -
6-37141724-A-C PIM1 c.799A>C p.I267L Missense 6/6 -
7-81392060-T-G HGF c.217A>C p.R73= Synonymous 2/18 -
10-89720680-A-C PTEN c.831A>C p.T277= Synonymous 8/9 -
4-106157821-G-T TET2 c.2722G>T p.G908C Missense 3/11 -
4-106157306-C-T TET2 c.2207C>T p.S736L Missense 3/11 -
4-106155166-C-A TET2 c.67C>A p.P23T Missense 3/11 -
4-55981452-C-G KDR c.485G>C p.C162S Missense 4/30 -
11-9595983-C-G WEE1 c.503C>G p.P168R Missense 1/11 -
4-106155416-T-G TET2 c.317T>G p.L106R Missense 3/11 -
22-50355264-G-C PIM3 c.421G>C p.A141P Missense 4/6 -
11-9595502-C-G WEE1 c.22C>G p.Q8E Missense 1/11 -
22-50354600-T-G PIM3 c.5T>G p.L2R Missense 1/6 -
19-1221229-G-T STK11 c.752G>T p.G251V Missense 6/10 -
5-1279479-A-G TERT c.2057T>C p.I686T Missense 5/16 -
19-30314580-A-C CCNE1 c.1129A>C p.K377Q Missense 12/12 -
19-18278062-A-G PIK3R2 c.1682A>G p.N561S Missense 13/16 -
17-29527613-G-T NF1 c.1062G>T p.K354N Missense 9/58 -
17-29490286-G-C NF1 c.371G>C p.C124S Missense 4/58 -
8-48866429-T-G PRKDC c.559A>C p.S187R Missense 6/87 -
8-48845665-A-C PRKDC c.1691T>G p.L564R Missense 16/87 -
20-62839603-A-C MYT1 c.1054A>C p.K352Q Missense 7/23 -
8-48869801-A-C PRKDC c.254T>G p.I85S Missense 3/87 -
20-62868694-A-C MYT1 c.3044A>C p.N1015T Missense 21/23 -
15-90628063-A-C IDH2 c.1256T>G p.I419S Missense 10/11 -
7-55227836-C-T EGFR c.1303C>T p.Q435* Nonsense 12/28 -
2-178098918-GTCGCTGACTGAAGTCAAATACTTC-G NFE2L2 c.103_126del24 p.E35_R42del InFrameDeletion 2/5 -
17-78599548-GA-CC RPTOR c.220_221delinsCC p.D74P Missense 2/34 -
4-106155289-ACCC-A TET2 c.190_192delCCC p.P64del InFrameDeletion 3/11 -
19-1207034-AGCG-A STK11 c.124_126delCGG p.R42del InFrameDeletion 1/10 -
16-2115611-T-G TSC2 c.1691T>G p.V564G Missense 16/42 -
18-39629513-C-T PIK3C3 c.2207C>T p.T736I Missense 21/25 -
1-11276278-T-G MTOR c.3044A>C p.Q1015P Missense 20/58 -
1-11316991-G-C MTOR c.503C>G p.A168G Missense 4/58 -
3-52668790-T-G PBRM1 c.1129A>C p.T377P Missense 12/30 -
19-30308143-C-G CCNE1 c.280C>G p.P94A Missense 5/12 -
11-534256-G-T HRAS c.67C>A p.L23M Missense 2/6 -
5-176517450-C-G FGFR4 c.151C>G p.Q51E Missense 3/18 -
17-78681777-G-C RPTOR c.485G>C p.G162A Missense 4/34 -
18-39542513-T-G PIK3C3 c.317T>G p.V106G Missense 3/25 -
2-178098863-T-A NFE2L2 c.182A>T p.Q61L Missense 2/5 -
1-11316236-C-T MTOR c.518G>A p.R173H Missense 5/58 -
2-178096532-T-G NFE2L2 c.799A>C p.T267P Missense 5/5 -
3-41266574-G-C CTNNB1 c.371G>C p.R124P Missense 4/15 -
11-9596039-A-C WEE1 c.559A>C p.T187P Missense 1/11 -
2-48026224-G-C MSH6 c.1102G>C p.E368Q Missense 4/10 -
4-55953774-C-A KDR c.3662G>T p.S1221I Missense 27/30 -
1-27023028-C-T ARID1A c.134C>T p.A45V Missense 1/20 -
13-32907308-G-C BRCA2 c.1693G>C p.A565P Missense 10/27 -
6-35423900-G-A FANCE c.625G>A p.A209T Missense 2/10 -
6-35434114-G-A FANCE c.1603G>A p.G535S Missense 10/10 -
1-46743791-C-G RAD54L c.2081C>G p.P694R Missense 18/18 -
1-46743631-G-A RAD54L c.2012G>A p.S671N Missense 17/18 -
5-79965925-C-T MSH3 c.589C>T p.L197F Missense 4/24 -
5-79966082-G-T MSH3 c.746G>T p.C249F Missense 4/24 -
8-48866389-A-G PRKDC c.599T>C p.F200S Missense 6/87 -
3-41275636-G-T CTNNB1 c.1531G>T p.V511F Missense 10/15 -
5-176721186-T-G NSD1 c.6817T>G p.C2273G Missense 23/23 -
17-7579891-G-C TP53 c.22C>G p.P8A Missense 2/11 -
12-133256540-C-A POLE c.423G>T p.L141F Missense 5/49 -
2-30143261-C-A ALK c.265G>T p.G89C Missense 1/29 -
2-212251686-T-C ERBB4 c.3373A>G p.T1125A Missense 27/28 -
19-1218488-G-A STK11 c.363G>A p.E121= Synonymous 2/10 -
16-68835632-T-G CDH1 c.223T>G p.F75V Missense 3/16 -
12-25378577-A-C KRAS c.421T>G p.F141V Missense 4/5 -
5-137803394-T-G EGR1 c.1256T>G p.L419W Missense 2/2 -
8-90996756-C-A NBN c.34G>T p.G12* Nonsense 1/16 -
19-11105568-G-A SMARCA4 c.1484G>A p.G495D Missense 9/35 -
2-29917880-C-A ALK c.788G>T p.G263V Missense 3/29 -
13-28609745-C-T FLT3 c.1484G>A p.W495* Nonsense 12/24 -
20-62863728-A-G MYT1 c.2887A>G p.T963A Missense 19/23 -
19-1220375-C-A STK11 c.468C>A p.Y156* Nonsense 4/10 -
4-55984774-G-A KDR c.355C>T p.Q119* Nonsense 3/30 -
3-41275726-G-A CTNNB1 c.1621G>A p.V541I Missense 10/15 -
17-63554509-C-A AXIN2 c.230G>T p.R77L Missense 2/11 -
X-70342990-G-T MED12 c.1531G>T p.A511S Missense 11/45 -
19-1219359-GG-TT STK11 c.411_412delinsTT p.Q137_E138delinsH* MultiAAMissense 3/10 -
13-28644659-G-A FLT3 c.134C>T p.S45L Missense 2/24 -
13-28589815-C-A FLT3 c.2565G>T p.M855I Missense 21/24 -
1-27088758-G-T ARID1A c.2367G>T p.Q789H Missense 7/20 -
12-58144865-C-T CDK4 c.363G>A p.M121I Missense 4/8 -
1-27087438-G-A ARID1A c.2012G>A p.G671E Missense 5/20 -
1-65325926-T-G JAK1 c.1196A>C p.H399P Missense 9/25 -
6-35423630-C-T FANCE c.355C>T p.Q119* Nonsense 2/10 -
21-36259244-C-T RUNX1 c.247G>A p.A83T Missense 4/9 -
12-46233219-G-T ARID2 c.1438G>T p.E480* Nonsense 11/21 -
1-46726495-C-T RAD54L c.574C>T p.Q192* Nonsense 7/18 -
4-55155207-G-T PDGFRA c.2806G>T p.E936* Nonsense 21/23 -
20-62854519-C-G MYT1 c.2452C>G p.H818D Missense 15/23 -
4-55127379-G-T PDGFRA c.167G>T p.S56I Missense 3/23 -
4-55961020-T-C KDR c.2920A>G p.S974G Missense 21/30 -
21-36206862-C-T RUNX1 c.650G>A p.G217E Missense 7/9 -
17-37882061-C-A ERBB2 c.2827C>A p.Q943K Missense 23/27 -
1-27105893-A-T ARID1A c.5504A>T p.Q1835L Missense 20/20 -
19-1220426-G-A STK11 c.519G>A p.V173= Synonymous 4/10 -
19-1221319-C-G STK11 c.842C>G p.P281R Missense 6/10 -
19-1226623-C-A STK11 c.1279C>A p.L427M Missense 9/10 -
1-9775790-G-T PIK3CD c.333G>T p.K111N Missense 4/24 -
1-27023030-G-C ARID1A c.136G>C p.E46Q Missense 1/20 -
1-27101654-G-C ARID1A c.4936G>C p.V1646L Missense 18/20 -
1-27023253-C-A ARID1A c.359C>A p.P120Q Missense 1/20 -
13-113900367-T-A CUL4A c.1628T>A p.L543* Nonsense 15/20 -
1-27101576-G-T ARID1A c.4858G>T p.V1620L Missense 18/20 -
6-152129300-G-T ESR1 c.253G>T p.E85* Nonsense 1/8 -
12-133249775-G-T POLE c.1448C>A p.T483N Missense 14/49 -
14-45628481-G-T FANCM c.1579G>T p.E527* Nonsense 9/23 -
12-133215880-G-A POLE c.5383C>T p.L1795= Synonymous 40/49 -
7-140482954-G-C BRAF c.1181C>G p.S394* Nonsense 10/18 -
16-2110792-A-T TSC2 c.1097A>T p.E366V Missense 11/42 -
13-32968918-C-A BRCA2 c.9349C>A p.H3117N Missense 25/27 -
22-50356640-G-C PIM3 c.846G>C p.P282= Synonymous 6/6 -
1-46726549-G-A RAD54L c.628G>A p.E210K Missense 7/18 -
19-10602692-G-T KEAP1 c.886C>A p.R296S Missense 3/6 -
17-29652860-G-T NF1 c.4858G>T p.G1620C Missense 37/58 -
17-37884133-G-T ERBB2 c.3604G>T p.G1202* Nonsense 27/27 -
13-32893399-G-T BRCA2 c.253G>T p.G85W Missense 3/27 -
19-1207000-G-T STK11 c.88G>T p.D30Y Missense 1/10 -
1-9780882-G-T PIK3CD c.1604G>T p.R535L Missense 13/24 -
1-27056283-C-A ARID1A c.1279C>A p.P427T Missense 2/20 -
14-45636238-G-A FANCM c.1874G>A p.S625N Missense 11/23 -
4-55133884-A-T PDGFRA c.1097A>T p.D366V Missense 7/23 -
14-45628350-C-A FANCM c.1448C>A p.S483Y Missense 9/23 -
4-106157551-C-G TET2 c.2452C>G p.P818A Missense 3/11 -
22-29091162-C-A CHEK2 c.1328G>T p.G443V Missense 12/15 -
19-11105559-C-A SMARCA4 c.1475C>A p.S492Y Missense 9/35 -
11-94209467-A-T MRE11 c.647T>A p.I216N Missense 7/20 -
19-11094880-C-T SMARCA4 c.53C>T p.P18L Missense 2/35 -
19-11114019-T-G SMARCA4 c.1947T>G p.Y649* Nonsense 13/35 -
2-29416123-T-A ALK c.4830A>T p.K1610N Missense 29/29 -
2-29498042-A-G ALK c.1964T>C p.L655P Missense 11/29 -
19-11129674-C-A SMARCA4 c.2480C>A p.P827H Missense 17/35 -
4-106156164-T-A TET2 c.1065T>A p.G355= Synonymous 3/11 -
21-42839742-A-T TMPRSS2 c.1386T>A p.G462= Synonymous 13/14 -
7-81335047-C-T HGF c.1780G>A p.V594I Missense 16/18 -
7-81346617-C-A HGF c.1336G>T p.D446Y Missense 11/18 -
3-37048536-T-G MLH1 c.435T>G p.N145K Missense 5/19 -
16-68855955-T-G CDH1 c.1763T>G p.V588G Missense 12/16 -
12-46215269-A-G ARID2 c.704A>G p.K235R Missense 6/21 -
7-140434500-A-G BRAF c.2198T>C p.L733S Missense 18/18 -
12-46123647-C-G ARID2 c.28C>G p.P10A Missense 1/21 -
12-46244462-G-T ARID2 c.2556G>T p.Q852H Missense 15/21 -
16-68863651-A-C CDH1 c.2390A>C p.Y797S Missense 15/16 -
17-78681713-G-C RPTOR c.421G>C p.A141P Missense 4/34 -
1-27101390-T-C ARID1A c.4672T>C p.S1558P Missense 18/20 -
1-150551346-G-A MCL1 c.661C>T p.Q221* Nonsense 1/3 -
1-27023265-G-C ARID1A c.371G>C p.G124A Missense 1/20 -
19-52723011-A-C PPP2R1A c.1196A>C p.Q399P Missense 10/15 -
19-10610676-C-A KEAP1 c.34G>T p.A12S Missense 2/6 -
4-55152023-C-T PDGFRA c.2455C>T p.L819= Synonymous 18/23 -
19-45867796-C-T ERCC2 c.604G>A p.A202T Missense 8/23 -
15-43701917-G-C TP53BP1 c.5328C>G p.F1776L Missense 25/28 -
15-43784619-G-T TP53BP1 c.55C>A p.Q19K Missense 2/28 -
13-28624265-G-C FLT3 c.709C>G p.L237V Missense 6/24 -
3-12653545-C-T RAF1 c.224G>A p.G75E Missense 3/17 -
17-29490249-C-A NF1 c.334C>A p.Q112K Missense 4/58 -
3-12626453-C-A RAF1 c.1696G>T p.A566S Missense 16/17 -
16-89882989-C-A FANCA c.35G>T p.G12V Missense 1/43 -
15-43738643-C-A TP53BP1 c.2982G>T p.M994I Missense 14/28 -
22-29121304-C-A CHEK2 c.371G>T p.C124F Missense 3/15 -
1-162731095-C-A DDR2 c.950C>A p.A317D Missense 9/18 -
5-176636890-C-G NSD1 c.1490C>G p.S497C Missense 5/23 -
16-89858883-C-A FANCA c.1079G>T p.R360L Missense 12/43 -
1-65325839-G-T JAK1 c.1283C>A p.A428D Missense 9/25 -
5-80083479-G-A MSH3 c.2531G>A p.G844E Missense 18/24 -
20-57485765-C-A GNAS c.1066C>A p.R356S Missense 13/13 -
6-37141748-C-A PIM1 c.823C>A p.P275T Missense 6/6 -
19-18266885-C-A PIK3R2 c.196C>A p.Q66K Missense 2/16 -
15-43708478-C-A TP53BP1 c.4818G>T p.G1606= Synonymous 22/28 -
17-29556281-C-A NF1 c.2648C>A p.S883* Nonsense 21/58 -
1-65339078-C-A JAK1 c.458G>T p.S153I Missense 5/25 -
2-215632354-G-A BARD1 c.1420C>T p.L474= Synonymous 6/11 -
8-38279404-A-G FGFR1 c.992T>C p.V331A Missense 8/18 -
12-46230748-G-T ARID2 c.997G>T p.D333Y Missense 8/21 -
7-140501243-G-T BRAF c.829C>A p.P277T Missense 6/18 -
12-46211462-G-T ARID2 c.428G>T p.R143L Missense 5/21 -
17-1782621-A-C RPA1 c.872A>C p.D291A Missense 10/17 -
11-108100028-C-G ATM c.309C>G p.Y103* Nonsense 4/63 -
3-12626656-C-T RAF1 c.1633G>A p.E545K Missense 15/17 -
17-29541523-G-T NF1 c.1447G>T p.D483Y Missense 13/58 -
3-52439304-G-T BAP1 c.938C>A p.A313E Missense 11/17 -
3-178951966-C-A PIK3CA c.3021C>A p.G1007= Synonymous 21/21 -
11-108206596-G-T ATM c.8176G>T p.A2726S Missense 56/63 -
11-108216612-G-T ATM c.8561G>T p.R2854L Missense 58/63 -
11-108122652-G-T ATM c.1696G>T p.V566L Missense 11/63 -
7-55227896-G-T EGFR c.1363G>T p.E455* Nonsense 12/28 -
5-80024726-G-T MSH3 c.1510G>T p.A504S Missense 10/24 -
7-116398625-C-A MET c.2215C>A p.R739S Missense 9/21 -
7-116398640-G-T MET c.2230G>T p.V744F Missense 9/21 -
8-6312761-G-T MCPH1 c.1923G>T p.G641= Synonymous 9/14 -
2-29940491-C-A ALK c.740G>T p.W247L Missense 2/29 -
11-108139296-C-A ATM c.2798C>A p.S933Y Missense 18/63 -
17-29556397-G-T NF1 c.2764G>T p.G922C Missense 21/58 -
17-29562642-G-T NF1 c.3722G>T p.R1241L Missense 28/58 -
17-29587387-G-T NF1 c.4431G>T p.R1477S Missense 34/58 -
17-29587460-G-T NF1 c.4504G>T p.G1502C Missense 34/58 -
2-29443671-G-T ALK c.3546C>A p.C1182* Nonsense 23/29 -
1-27099325-C-A ARID1A c.3562C>A p.Q1188K Missense 14/20 -
13-48921989-C-A RB1 c.529C>A p.P177T Missense 5/27 -
13-48953735-C-A RB1 c.1338C>A p.Y446* Nonsense 14/27 -
13-48954331-G-T RB1 c.1452G>T p.M484I Missense 16/27 -
17-29667522-GGACTC-G NF1 c.6923_6927delACTCG p.D2308Afs*17 SpliceAcceptorDeletion 47/58 -
15-43748274-TCT-ATG TP53BP1 c.2530_2532delAGAinsCAT p.R844H Missense 12/28 -
X-53250076-ACAG-A KDM5C c.170_172delCTG p.A57del InFrameDeletion 2/26 -
17-29509667-A-C NF1 c.872A>C p.E291A Missense 8/58 -
2-215645894-G-T BARD1 c.704C>A p.S235Y Missense 4/11 -
2-42557199-C-A EML4 c.2798C>A p.P933Q Missense 23/23 -
3-12653460-G-C RAF1 c.309C>G p.H103Q Missense 3/17 -
22-24175838-C-A SMARCB1 c.1066C>A p.L356M Missense 8/9 -
19-18272783-C-A PIK3R2 c.823C>A p.P275T Missense 7/16 -
17-1747932-G-A RPA1 c.224G>A p.C75Y Missense 4/17 -
13-28636038-G-T FLT3 c.334C>A p.L112M Missense 3/24 -
19-10610655-G-T KEAP1 c.55C>A p.L19M Missense 2/6 -
1-27106805-C-A ARID1A c.6416C>A p.P2139H Missense 20/20 -
X-53223906-C-A KDM5C c.3453G>T p.K1151N Missense 23/26 -
X-76814277-C-A ATRX c.6367G>T p.G2123* Nonsense 29/35 -
15-43749359-C-A TP53BP1 c.1447G>T p.G483* Nonsense 12/28 -
19-11170770-G-T SMARCA4 c.4818G>T p.Q1606H Missense 34/35 -
3-12641703-G-T RAF1 c.938C>A p.P313Q Missense 9/17 -
X-53223813-G-T KDM5C c.3546C>A p.S1182= Synonymous 23/26 -
11-108142077-C-A ATM c.3021C>A p.D1007E Missense 20/63 -
15-43762235-C-T TP53BP1 c.1210G>A p.E404K Missense 11/28 -
16-89849491-G-C FANCA c.1490C>G p.P497R Missense 16/43 -
3-12632304-C-A RAF1 c.1363G>T p.G455* Nonsense 12/17 -
1-65303773-C-A JAK1 c.2982G>T p.L994F Missense 22/25 -
7-140477798-C-A BRAF c.1510G>T p.V504L Missense 12/18 -
1-11181305-C-A MTOR c.6931G>T p.E2311* Nonsense 49/58 -
1-162724599-G-T DDR2 c.371G>T p.R124L Missense 5/18 -
19-52723098-C-A PPP2R1A c.1283C>A p.P428H Missense 10/15 -
15-43748883-C-A TP53BP1 c.1923G>T p.E641D Missense 12/28 -
10-43598056-G-A RET c.604G>A p.V202M Missense 3/20 -
11-22646560-C-G FANCF c.797G>C p.R266P Missense 1/1 -
9-5044497-G-C JAK2 c.445G>C p.V149L Missense 5/25 -
21-39817533-T-G ERG c.30A>C p.S10= Synonymous 2/10 -
15-43771596-T-G TP53BP1 c.787A>C p.R263= Synonymous 7/28 -
7-55233046-T-G EGFR c.1796T>G p.V599G Missense 15/28 -
5-80088599-A-C MSH3 c.2591A>C p.H864P Missense 19/24 -
2-29606660-A-C ALK c.1220T>G p.I407S Missense 5/29 -
9-5081833-A-G JAK2 c.2543A>G p.H848R Missense 19/25 -
17-37872091-A-C ERBB2 c.1412A>C p.N471T Missense 12/27 -
17-37872093-A-C ERBB2 c.1414A>C p.T472P Missense 12/27 -
17-37872616-A-C ERBB2 c.1576A>C p.T526P Missense 13/27 -
17-37879622-T-G ERBB2 c.1997T>G p.V666G Missense 17/27 -
17-37882062-A-C ERBB2 c.2828A>C p.Q943P Missense 23/27 -
15-43701167-T-G TP53BP1 c.5528A>C p.N1843T Missense 26/28 -
17-37864596-A-C ERBB2 c.248A>C p.Y83S Missense 3/27 -
17-62009587-T-G CD79B c.35A>C p.H12P Missense 1/6 -
17-47699416-T-G SPOP c.92A>C p.K31T Missense 3/10 -
1-9778819-T-G PIK3CD c.1088T>G p.V363G Missense 9/24 -
1-9783253-A-C PIK3CD c.2497A>C p.T833P Missense 20/24 -
15-43701180-T-G TP53BP1 c.5515A>C p.S1839R Missense 26/28 -
2-215593671-T-G BARD1 c.2063A>C p.K688T Missense 11/11 -
1-27094366-A-G ARID1A c.3074A>G p.D1025G Missense 11/20 -
1-27105953-T-C ARID1A c.5564T>C p.I1855T Missense 20/20 -
1-27106301-T-G ARID1A c.5912T>G p.L1971R Missense 20/20 -
17-47699325-T-G SPOP c.183A>C p.A61= Synonymous 3/10 -
1-9782626-C-A PIK3CD c.2388C>A p.L796= Synonymous 19/24 -
1-65316546-G-C JAK1 c.1696C>G p.P566A Missense 12/25 -
1-65316557-T-G JAK1 c.1685A>C p.Q562P Missense 12/25 -
1-27023796-C-A ARID1A c.902C>A p.S301* Nonsense 1/20 -
1-150550910-A-C MCL1 c.746T>G p.V249G Missense 2/3 -
17-41228533-T-G BRCA1 c.4456A>C p.S1486R Missense 13/23 -
1-11292509-A-C MTOR c.2498T>G p.L833W Missense 16/58 -
1-226573248-A-C PARP1 c.968T>G p.V323G Missense 7/23 -
1-226590014-A-G PARP1 c.187T>C p.S63P Missense 2/23 -
1-65344771-T-G JAK1 c.266A>C p.Y89S Missense 4/25 -
1-65307183-C-A JAK1 c.2505G>T p.R835S Missense 18/25 -
16-2127632-G-T TSC2 c.2871G>T p.L957F Missense 26/42 -
15-43739580-T-G TP53BP1 c.2820A>C p.R940S Missense 13/28 -
16-89877443-A-C FANCA c.320T>G p.V107G Missense 4/43 -
16-2104385-T-G TSC2 c.425T>G p.V142G Missense 5/42 -
16-2106238-A-C TSC2 c.641A>C p.D214A Missense 7/42 -
1-9778897-G-C PIK3CD c.1166G>C p.R389P Missense 9/24 -
16-89805892-A-T FANCA c.4004T>A p.F1335Y Missense 40/43 -
3-52696168-T-C PBRM1 c.509A>G p.Q170R Missense 5/30 -
3-138474778-A-C PIK3CB c.215T>G p.L72R Missense 4/24 -
3-191888405-A-C FGF12 c.269T>G p.F90C Missense 5/6 -
X-47422668-A-C ARAF c.140A>C p.K47T Missense 3/16 -
X-70349021-A-C MED12 c.3533A>C p.H1178P Missense 25/45 -
3-52692216-A-G PBRM1 c.644T>C p.V215A Missense 6/30 -
12-56493504-A-C ERBB3 c.2912A>C p.D971A Missense 24/28 -
12-56481908-A-C ERBB3 c.836A>C p.K279T Missense 7/28 -
12-58143270-T-G CDK4 c.650A>C p.N217T Missense 6/8 -
12-58145398-T-G CDK4 c.103A>C p.K35Q Missense 2/8 -
12-58145404-C-G CDK4 c.97G>C p.A33P Missense 2/8 -
12-58145469-T-C CDK4 c.32A>G p.E11G Missense 2/8 -
12-58145487-C-G CDK4 c.14G>C p.R5P Missense 2/8 -
12-58145494-T-G CDK4 c.7A>C p.T3P Missense 2/8 -
12-56477556-G-A ERBB3 c.104G>A p.G35D Missense 2/28 -
12-69207340-C-A MDM2 c.106C>A p.P36T Missense 3/11 -
12-69222697-A-C MDM2 c.670A>C p.T224P Missense 8/11 -
12-69229652-A-G MDM2 c.728A>G p.D243G Missense 9/11 -
12-69229661-C-T MDM2 c.737C>T p.S246L Missense 9/11 -
12-69230483-A-G MDM2 c.872A>G p.E291G Missense 10/11 -
12-69230487-T-G MDM2 c.876T>G p.S292R Missense 10/11 -
X-70346891-A-C MED12 c.2758A>C p.T920P Missense 20/45 -
12-133245407-T-G POLE c.1913A>C p.N638T Missense 17/49 -
X-47426077-C-G ARAF c.597C>G p.F199L Missense 7/16 -
20-31022325-T-C ASXL1 c.1810T>C p.S604P Missense 13/13 -
20-31024754-A-C ASXL1 c.4239A>C p.L1413F Missense 13/13 -
20-31021659-A-G ASXL1 c.1658A>G p.E553G Missense 12/13 -
16-89871800-G-C FANCA c.597C>G p.S199R Missense 7/43 -
2-29455211-T-G ALK c.2591A>C p.N864T Missense 15/29 -
2-30143081-C-G ALK c.445G>C p.A149P Missense 1/29 -
17-37657626-A-G CDK12 c.2543A>G p.E848G Missense 6/14 -
21-39817380-T-G ERG c.183A>C p.P61= Synonymous 2/10 -
7-55219029-G-C EGFR c.602G>C p.G201A Missense 5/28 -
17-37618359-A-C CDK12 c.35A>C p.D12A Missense 1/14 -
1-9770605-A-C PIK3CD c.92A>C p.Y31S Missense 3/24 -
9-5022017-A-C JAK2 c.30A>C p.E10D Missense 3/25 -
9-97873854-A-C FANCC c.1220T>G p.V407G Missense 13/15 -
1-11190684-T-G MTOR c.5515A>C p.T1839P Missense 39/58 -
1-27105917-A-C ARID1A c.5528A>C p.H1843P Missense 20/20 -
12-133245052-T-G POLE c.2063A>C p.H688P Missense 19/49 -
1-150550754-G-T MCL1 c.902C>A p.T301K Missense 2/3 -
13-49047504-T-G RB1 c.2498T>G p.V833G Missense 24/27 -
13-22246317-A-C FGF9 c.266A>C p.H89P Missense 1/3 -
13-25030536-C-A PARP4 c.2505G>T p.L835F Missense 21/34 -
16-89828389-T-G FANCA c.2820A>C p.Q940H Missense 29/43 -
13-25068811-T-G PARP4 c.641A>C p.Y214S Missense 7/34 -
3-51979581-T-G PARP3 c.953T>G p.V311G Missense 7/11 -
12-58145286-A-C CDK4 c.215T>G p.V72G Missense 2/8 -
3-52442560-A-C BAP1 c.185T>G p.V62G Missense 4/17 -
21-36259222-A-C RUNX1 c.269T>G p.V90G Missense 4/9 -
9-5089805-C-G JAK2 c.2703C>G p.I901M Missense 20/25 -
3-51978915-T-C PARP3 c.644T>C p.L208P Missense 5/11 -
5-79968106-A-C MSH3 c.836A>C p.N279T Missense 5/24 -
1-65309762-G-T JAK1 c.2388C>A p.D796E Missense 17/25 -
3-52713624-C-T PBRM1 c.104G>A p.R35K Missense 2/30 -
X-70346941-C-A MED12 c.2808C>A p.C936* Nonsense 20/45 -
19-10610429-A-G KEAP1 c.281T>C p.M94T Missense 2/6 -
9-80646117-C-A GNAQ c.35G>T p.S12I Missense 1/7 -
3-41275215-A-G CTNNB1 c.1381A>G p.T461A Missense 9/15 -
2-190656645-C-T PMS1 c.110C>T p.A37V Missense 2/13 -
13-22246242-G-A FGF9 c.191G>A p.R64K Missense 1/3 -
9-80336415-C-A GNAQ c.904G>T p.A302S Missense 7/7 -
5-80168949-G-T MSH3 c.3145G>T p.V1049F Missense 23/24 -
9-80646140-C-A GNAQ c.12G>T p.E4D Missense 1/7 -
2-29448351-G-T ALK c.3148C>A p.L1050M Missense 19/29 -
3-178937473-A-G PIK3CA c.1861A>G p.K621E Missense 12/21 -
3-178921383-G-T PIK3CA c.865G>T p.A289S Missense 5/21 -
3-178916698-G-C PIK3CA c.85G>C p.G29R Missense 2/21 -
11-108098389-G-T ATM c.38G>T p.R13L Missense 2/63 -
3-178942609-G-T PIK3CA c.2416G>T p.D806Y Missense 16/21 -
8-133900811-C-A TG c.2759C>A p.T920K Missense 10/48 -
22-41513511-G-T EP300 c.415G>T p.G139C Missense 2/31 -
17-78599536-G-T RPTOR c.208G>T p.V70L Missense 2/34 -
8-133912530-G-A TG c.3379G>A p.V1127M Missense 15/48 -
20-31017168-G-T ASXL1 c.499G>T p.V167L Missense 7/13 -
5-131927707-G-A RAD50 c.1774G>A p.D592N Missense 11/25 -
8-134125778-G-T TG c.7685G>T p.W2562L Missense 44/48 -
5-131923679-G-T RAD50 c.949G>T p.E317* Nonsense 7/25 -
5-131930625-G-T RAD50 c.1858G>T p.E620* Nonsense 12/25 -
8-133911052-C-A TG c.3227C>A p.T1076N Missense 14/48 -
1-27106987-G-A ARID1A c.6598G>A p.E2200K Missense 20/20 -
2-42553369-G-T EML4 c.2318G>T p.C773F Missense 21/23 -
16-68857491-C-A CDH1 c.2126C>A p.A709D Missense 13/16 -
17-62007658-C-A CD79B c.206G>T p.S69I Missense 3/6 -
3-37042513-C-A MLH1 c.275C>A p.A92D Missense 3/19 -
12-133256789-G-A POLE c.305C>T p.P102L Missense 4/49 -
3-37061871-G-T MLH1 c.955G>T p.E319* Nonsense 11/19 -
12-133237695-T-C POLE c.2920A>G p.K974E Missense 25/49 -
22-41574510-TCAG-T EP300 c.6798_6800delGCA p.Q2268del InFrameDeletion 31/31 -
2-39262551-C-A SOS1 c.955G>T p.G319W Missense 7/23 -
2-48028042-A-G MSH6 c.2920A>G p.R974G Missense 4/10 -
1-27087552-C-A ARID1A c.2126C>A p.S709Y Missense 5/20 -
1-243828083-G-T AKT3 c.275C>A p.P92Q Missense 4/14 -
9-80430677-G-T GNAQ c.331C>A p.Q111K Missense 3/7 -
19-10602713-C-A KEAP1 c.865G>T p.E289* Nonsense 3/6 -
3-41266484-T-C CTNNB1 c.281T>C p.V94A Missense 4/15 -
13-28623608-C-A FLT3 c.949G>T p.V317L Missense 8/24 -
20-31023894-G-A ASXL1 c.3379G>A p.D1127N Missense 13/13 -
2-30143318-C-A ALK c.208G>T p.D70Y Missense 1/29 -
17-29683547-G-T NF1 c.7685G>T p.G2562V Missense 52/58 -
8-133899391-G-A TG c.1774G>A p.A592T Missense 9/48 -
5-80021312-A-G MSH3 c.1381A>G p.I461V Missense 9/24 -
5-80168952-C-A MSH3 c.3148C>A p.P1050T Missense 23/24 -
19-10610672-C-A KEAP1 c.38G>T p.C13F Missense 2/6 -
X-48775899-C-G PIM2 c.85G>C p.E29Q Missense 2/6 -
17-29486029-G-T NF1 c.206G>T p.R69I Missense 3/58 -
17-29556049-G-T NF1 c.2416G>T p.E806* Nonsense 21/58 -
5-80109506-C-A MSH3 c.2759C>A p.S920Y Missense 20/24 -
15-66735678-G-T MAP2K1 c.499G>T p.G167* Nonsense 4/11 -
2-42483737-C-T EML4 c.305C>T p.A102V Missense 3/23 -
4-72620742-C-A GC c.1117G>T p.G373C Missense 9/13 -
3-51978885-G-A PARP3 c.614G>A p.S198N Missense 5/11 -
19-10602296-C-A KEAP1 c.1282G>T p.V428F Missense 3/6 -
3-51979052-C-A PARP3 c.694C>A p.Q225K Missense 6/11 -
12-46254717-G-T ARID2 c.4907G>T p.W1636L Missense 16/21 -
1-27106142-G-T ARID1A c.5753G>T p.R1918L Missense 20/20 -
1-27100371-G-T ARID1A c.4083G>T p.M1361I Missense 17/20 -
1-27092725-C-A ARID1A c.2746C>A p.P916T Missense 9/20 -
7-55087058-G-T EGFR c.88G>T p.V30F Missense 1/28 -
19-1207066-G-A STK11 c.154G>A p.G52R Missense 1/10 -
20-57484829-T-G GNAS c.809T>G p.L270R Missense 10/13 -
15-90630425-G-T IDH2 c.886C>A p.Q296K Missense 7/11 -
14-45633584-G-T FANCM c.1604G>T p.G535V Missense 10/23 -
1-27101625-G-T ARID1A c.4907G>T p.R1636L Missense 18/20 -
19-1221966-C-A STK11 c.881C>A p.P294Q Missense 7/10 -
1-243809228-C-A AKT3 c.396G>T p.E132D Missense 5/14 -
4-106156381-G-T TET2 c.1282G>T p.G428C Missense 3/11 -
2-48010539-G-T MSH6 c.167G>T p.G56V Missense 1/10 -
X-14883041-G-C FANCB c.592C>G p.Q198E Missense 3/10 -
21-36206818-G-T RUNX1 c.694C>A p.R232= Synonymous 7/9 -
7-55221802-G-C EGFR c.846G>C p.E282D Missense 7/28 -
19-10610463-C-T KEAP1 c.247G>A p.V83I Missense 2/6 -
3-178947871-C-A PIK3CA c.2746C>A p.R916S Missense 19/21 -
8-133941383-G-A TG c.4762G>A p.A1588T Missense 23/48 -
10-43606769-G-T RET c.1378G>T p.D460Y Missense 7/20 -
8-133883653-CA-TG TG c.335_336delinsTG p.T112M Missense 4/48 -
16-68857312-T-G CDH1 c.1947T>G p.S649= Synonymous 13/16 -
1-27056332-G-T ARID1A c.1328G>T p.G443V Missense 2/20 -
4-55138659-G-T PDGFRA c.1336G>T p.E446* Nonsense 9/23 -
3-37035066-C-G MLH1 c.28C>G p.R10G Missense 1/19 -
16-68835780-G-C CDH1 c.371G>C p.R124P Missense 3/16 -
5-176519395-GG-CT FGFR4 c.801_802delinsCT p.E268* Missense 7/18 -
16-68835663-T-G CDH1 c.254T>G p.V85G Missense 3/16 -
13-28623900-T-G FLT3 c.754A>C p.T252P Missense 7/24 -
4-55981052-A-T KDR c.647T>A p.V216D Missense 5/30 -
15-99465388-A-G IGF1R c.2213A>G p.K738R Missense 11/21 -
17-37880986-A-ACGTGATGGCCTC ERBB2 c.2324_2325insCTCCGTGATGGC p.A775_G776insSVMA InFrameInsertion 20/27 -
3-185165600-C-T MAP3K13 c.875C>T p.A292V Missense 5/14 -
12-25362823-G-T KRAS c.473C>A p.T158K Missense 5/5 -
12-46244245-C-A ARID2 c.2339C>A p.P780Q Missense 15/21 -
12-25378580-G-T KRAS c.418C>A p.P140T Missense 4/5 -
5-112162906-G-T APC c.1510G>T p.A504S Missense 12/16 -
21-42860417-C-A TMPRSS2 c.349G>T p.G117W Missense 5/14 -
17-7576876-C-A TP53 c.970G>T p.D324Y Missense 9/11 -
8-133906057-G-A TG c.2884G>A p.G962R Missense 11/48 -
17-41246710-C-A BRCA1 c.838G>T p.A280S Missense 10/23 -
3-178919161-G-T PIK3CA c.646G>T p.V216L Missense 4/21 -
7-116395542-T-C MET c.1835T>C p.L612S Missense 6/21 -
7-152346386-T-A XRCC2 c.184A>T p.T62S Missense 3/3 -
19-1226467-G-T STK11 c.1123G>T p.E375* Nonsense 9/10 -
17-7579552-C-A TP53 c.135G>T p.L45= Synonymous 4/11 -
15-99442759-G-T IGF1R c.1156G>T p.G386C Missense 5/21 -
3-52643815-G-T PBRM1 c.2081C>A p.P694H Missense 17/30 -
5-176520255-G-T FGFR4 c.1174G>T p.G392W Missense 9/18 -
11-108199766-A-G ATM c.7108A>G p.N2370D Missense 49/63 -
8-133900634-T-A TG c.2582T>A p.I861N Missense 10/48 -
7-55223561-G-T EGFR c.928G>T p.A310S Missense 8/28 -
11-77048439-C-A PAK1 c.1146G>T p.S382= Synonymous 12/15 -
9-133760655-C-T ABL1 c.2978C>T p.A993V Missense 11/11 -
11-77070014-C-T PAK1 c.526G>A p.D176N Missense 6/15 -
3-178917627-C-G PIK3CA c.502C>G p.P168A Missense 3/21 -
9-133759476-T-A ABL1 c.1799T>A p.F600Y Missense 11/11 -
13-25043223-T-C PARP4 c.2072A>G p.Q691R Missense 17/34 -
15-43767848-A-C TP53BP1 c.1000T>G p.C334G Missense 9/28 -
19-17953372-A-C JAK3 c.614T>G p.L205R Missense 6/24 -
20-62871712-A-C MYT1 c.3277A>C p.T1093P Missense 23/23 -
5-112179299-A-C APC c.8008A>C p.R2670= Synonymous 16/16 -
8-48869792-A-C PRKDC c.263T>G p.F88C Missense 3/87 -
10-43604536-T-G RET c.1121T>G p.V374G Missense 6/20 -
19-10610166-T-G KEAP1 c.544A>C p.S182R Missense 2/6 -
19-10610378-A-G KEAP1 c.332T>C p.F111S Missense 2/6 -
19-17953219-A-C JAK3 c.767T>G p.V256G Missense 6/24 -
19-10602798-T-G KEAP1 c.780A>C p.R260= Synonymous 3/6 -
15-43738723-T-C TP53BP1 c.2902A>G p.T968A Missense 14/28 -
5-1282607-T-G TERT c.1706A>C p.Q569P Missense 3/16 -
5-67575558-C-A PIK3R1 c.631C>A p.P211T Missense 5/16 -
7-55225422-T-C EGFR c.1274T>C p.I425T Missense 11/28 -
17-37872805-C-G ERBB2 c.1684C>G p.P562A Missense 14/27 -
5-112154858-A-C APC c.1129A>C p.K377Q Missense 10/16 -
9-5078385-A-G JAK2 c.2072A>G p.N691S Missense 16/25 -
7-55227833-G-C EGFR c.1300G>C p.G434R Missense 12/28 -
20-62838966-C-A MYT1 c.417C>A p.S139= Synonymous 7/23 -
5-176637228-C-A NSD1 c.1828C>A p.Q610K Missense 5/23 -
22-41573159-A-T EP300 c.5444A>T p.Q1815L Missense 31/31 -
17-29559855-A-G NF1 c.3452A>G p.N1151S Missense 26/58 -
17-37687166-A-T CDK12 c.4070A>T p.N1357I Missense 14/14 -
X-76953071-C-A ATRX c.242G>T p.R81M Missense 4/35 -
X-76944373-C-G ATRX c.532G>C p.V178L Missense 7/35 -
X-76949372-T-C ATRX c.425A>G p.K142R Missense 6/35 -
13-32918790-G-T BRCA2 c.6937G>T p.G2313C Missense 12/27 -
20-62839489-C-T MYT1 c.940C>T p.Q314* Nonsense 7/23 -
19-10610243-A-C KEAP1 c.467T>G p.M156R Missense 2/6 -
5-112176161-T-G APC c.4870T>G p.L1624V Missense 16/16 -
5-112176825-A-C APC c.5534A>C p.H1845P Missense 16/16 -
1-11288793-G-A MTOR c.2962C>T p.Q988* Nonsense 19/58 -
2-47637375-A-C MSH2 c.509A>C p.Q170P Missense 3/16 -
11-9597504-G-T WEE1 c.646G>T p.D216Y Missense 2/11 -
2-178096069-T-A NFE2L2 c.1262A>T p.Q421L Missense 5/5 -
8-48826469-G-T PRKDC c.2773C>A p.Q925K Missense 24/87 -
17-63554310-G-C AXIN2 c.429C>G p.S143R Missense 2/11 -
3-38180331-G-C MYD88 c.179G>C p.W47S Missense 1/5 -
6-35420347-C-G FANCE c.25C>G p.P9A Missense 1/10 -
9-133750406-T-C ABL1 c.1237T>C p.Y413H Missense 7/11 -
20-57466822-A-C GNAS c.41A>C p.N14T Missense 1/13 -
8-48866276-T-G PRKDC c.625A>C p.T209P Missense 7/87 -
8-48815354-T-G PRKDC c.3044A>C p.D1015A Missense 27/87 -
19-18273925-C-G PIK3R2 c.1258C>G p.R420G Missense 10/16 -
19-52724286-T-G PPP2R1A c.1418T>G p.F473C Missense 12/15 -
16-2131613-A-G TSC2 c.3628A>G p.M1210V Missense 31/42 -
5-176637646-ATGC-A NSD1 c.2248_2250delGCT p.A750del InFrameDeletion 5/23 -
19-11169025-T-C SMARCA4 c.4519T>C p.F1507L Missense 31/35 -
9-5123023-A-C JAK2 c.3079A>C p.T1027P Missense 23/25 -
17-56772409-T-G RAD51C c.263T>G p.L88R Missense 2/9 -
13-32937491-A-G BRCA2 c.8152A>G p.I2718V Missense 18/27 -
5-67591091-C-G PIK3R1 c.1684C>G p.R562G Missense 13/16 -
9-135772644-T-C TSC1 c.2902A>G p.R968G Missense 22/23 -
2-212530091-G-T ERBB4 c.1828C>A p.P610T Missense 15/28 -
17-63533917-A-G AXIN2 c.1237T>C p.S413P Missense 6/11 -
9-135781259-T-G TSC1 c.1706A>C p.D569A Missense 15/23 -
7-81399247-T-G HGF c.41A>C p.H14P Missense 1/18 -
7-81355253-A-C HGF c.1121T>G p.V374G Missense 9/18 -
5-176636674-T-C NSD1 c.1274T>C p.V425A Missense 5/23 -
2-212576899-A-C ERBB4 c.1000T>G p.C334G Missense 9/28 -
19-44056992-T-G XRCC1 c.780A>C p.K260N Missense 8/17 -
X-70356862-A-C MED12 c.5534A>C p.N1845T Missense 38/45 -
5-176562718-T-G NSD1 c.614T>G p.V205G Missense 2/23 -
5-176562735-C-A NSD1 c.631C>A p.Q211K Missense 2/23 -
X-70340913-G-T MED12 c.646G>T p.G216C Missense 5/45 -
14-20824781-A-T PARP2 c.1262A>T p.N421I Missense 13/16 -
22-41537053-C-A EP300 c.1880C>A p.A627E Missense 10/31 -
2-212288973-G-T ERBB4 c.2773C>A p.P925T Missense 23/28 -
19-11095006-G-C SMARCA4 c.179G>C p.G60A Missense 2/35 -
19-11138491-G-T SMARCA4 c.3247G>T p.E1083* Nonsense 24/35 -
2-47672710-G-C MSH2 c.1300G>C p.A434P Missense 8/16 -
11-108153488-A-G ATM c.3628A>G p.M1210V Missense 25/63 -
5-176520519-C-A FGFR4 c.1364C>A p.P455H Missense 10/18 -
2-190738322-A-T PMS1 c.2574A>T p.L858F Missense 12/13 -
11-108175537-T-C ATM c.5632T>C p.S1878P Missense 37/63 -
X-70346231-T-A MED12 c.2582T>A p.L861H Missense 19/45 -
1-27023055-C-T ARID1A c.161C>T p.A54V Missense 1/20 -
5-1264612-G-A TERT c.2750C>T p.T917M Missense 11/16 -
X-53224184-G-A KDM5C c.3367C>T p.L1123= Synonymous 22/26 -
5-112155003-A-G APC c.1274A>G p.E425G Missense 10/16 -
5-170818387-A-C NPM1 c.217A>C p.K73Q Missense 3/11 -
1-150551610-G-C MCL1 c.397C>G p.P133A Missense 1/3 -
17-37883779-C-T ERBB2 c.3391C>T p.L1131= Synonymous 26/27 -
8-128750920-T-G MYC c.457T>G p.F153V Missense 2/3 -
12-25378616-T-C KRAS c.382A>G p.K128E Missense 4/5 -
13-32912612-A-T BRCA2 c.4120A>T p.K1374* Nonsense 11/27 -
3-52643594-C-A PBRM1 c.2302G>T p.D768Y Missense 17/30 -
2-42472659-G-T EML4 c.40G>T p.A14S Missense 2/23 -
1-45797967-C-G MUTYH c.720G>C p.Q240H Missense 10/16 -
13-113917872-G-C CUL4A c.2256G>C p.P752= Synonymous 20/20 -
3-52620503-C-A PBRM1 c.3250G>T p.D1084Y Missense 21/30 -
9-133759853-G-A ABL1 c.2176G>A p.A726T Missense 11/11 -
7-140534418-C-G BRAF c.495G>C p.Q165H Missense 3/18 -
7-140624502-A-G BRAF c.2T>C p.M1? Missense 1/18 -
3-178917543-C-A PIK3CA c.418C>A p.R140= Synonymous 3/21 -
3-178917545-A-C PIK3CA c.420A>C p.R140= Synonymous 3/21 -
3-178917545-A-G PIK3CA c.420A>G p.R140= Synonymous 3/21 -
3-178917545-A-T PIK3CA c.420A>T p.R140= Synonymous 3/21 -
5-176524618-C-A FGFR4 c.2350C>A p.H784N Missense 18/18 -
8-133911075-G-T TG c.3250G>T p.G1084W Missense 14/48 -
3-178922356-A-T PIK3CA c.1125A>T p.R375S Missense 6/21 -
19-1219344-C-A STK11 c.396C>A p.C132* Nonsense 3/10 -
17-37871546-G-T ERBB2 c.1156G>T p.A386S Missense 10/27 -
15-43784269-T-G TP53BP1 c.217A>C p.T73P Missense 3/28 -
2-42488319-C-G EML4 c.397C>G p.H133D Missense 4/23 -
15-90631623-C-A IDH2 c.646G>T p.G216C Missense 5/11 -
15-99467201-T-A IGF1R c.2582T>A p.L861* Nonsense 12/21 -
22-41572966-G-T EP300 c.5251G>T p.A1751S Missense 31/31 -
2-29917740-C-A ALK c.928G>T p.E310* Nonsense 3/29 -
8-133885337-G-T TG c.509G>T p.R170L Missense 5/48 -
15-90631880-G-T IDH2 c.473C>A p.P158Q Missense 4/11 -
19-11130307-G-T SMARCA4 c.2546G>T p.R849L Missense 18/35 -
7-148543687-T-C EZH2 c.121A>G p.M41V Missense 3/20 -
12-46230525-A-T ARID2 c.774A>T p.E258D Missense 8/21 -
19-1226490-G-T STK11 c.1146G>T p.Q382H Missense 9/10 -
19-17953876-C-T JAK3 c.526G>A p.E176K Missense 5/24 -
7-152346430-T-C XRCC2 c.140A>G p.H47R Missense 3/3 -
11-532704-G-C HRAS c.502C>G p.L168V Missense 5/6 -
5-79952341-G-T MSH3 c.349G>T p.G117C Missense 2/24 -
1-27022934-G-T ARID1A c.40G>T p.G14C Missense 1/20 -
1-27023864-G-T ARID1A c.970G>T p.G324C Missense 1/20 -
7-148506182-C-T EZH2 c.2176G>A p.E726K Missense 19/20 -
7-55214369-G-C EGFR c.495G>C p.R165= Synonymous 4/28 -
7-116397496-A-G MET c.1868A>G p.K623R Missense 7/21 -
3-178921356-G-T PIK3CA c.838G>T p.G280W Missense 5/21 -
16-89828391-G-T FANCA c.2818C>A p.Q940K Missense 29/43 -
10-103530295-C-T FGF8 c.526G>A p.E176K Missense 6/6 -
17-37880997-G-GTCT ERBB2 c.2326_2327insTCT p.G776delinsVC MultiAAMissense 20/27 -
17-29533291-G-T NF1 c.1294G>T p.V432L Missense 12/58 -
11-533548-C-G HRAS c.355G>C p.D119H Missense 4/6 -
11-532711-C-G HRAS c.495G>C p.Q165H Missense 5/6 -
5-79950707-C-T MSH3 c.161C>T p.A54V Missense 1/24 -
5-80088582-A-T MSH3 c.2574A>T p.V858= Synonymous 19/24 -
2-48026245-G-T MSH6 c.1123G>T p.E375* Nonsense 4/10 -
17-29657336-T-C NF1 c.5632T>C p.C1878R Missense 39/58 -
7-81359026-C-G HGF c.935G>C p.G312A Missense 8/18 -
3-10128903-A-T FANCD2 c.3421A>T p.I1141F Missense 34/44 -
11-108123613-G-C ATM c.1872G>C p.M624I Missense 12/63 -
3-142272569-C-A ATR c.2546G>T p.R849I Missense 12/47 -
3-168830608-C-A MECOM c.2544G>T p.L848F Missense 9/17 -
3-168833385-A-G MECOM c.2275T>C p.S759P Missense 8/17 -
15-43762262-T-G TP53BP1 c.1183A>C p.K395Q Missense 11/28 -
9-35076814-T-G FANCG c.831A>C p.S277= Synonymous 7/14 -
17-29496953-A-G NF1 c.524A>G p.H175R Missense 5/58 -
3-168807866-T-C MECOM c.3323A>G p.N1108S Missense 15/17 -
9-5050770-G-T JAK2 c.553G>T p.D185Y Missense 6/25 -
14-45668130-G-C FANCM c.6000G>C p.M2000I Missense 22/23 -
X-53241015-T-G KDM5C c.1196A>C p.E399A Missense 9/26 -
14-45644539-T-A FANCM c.2582T>A p.I861K Missense 14/23 -
X-53228330-T-C KDM5C c.2072A>G p.E691G Missense 15/26 -
3-142272124-G-A ATR c.2750C>T p.A917V Missense 13/47 -
X-70355093-T-G MED12 c.5015T>G p.F1672C Missense 36/45 -
15-43773147-T-G TP53BP1 c.445A>C p.K149Q Missense 5/28 -
1-27023343-T-A ARID1A c.449T>A p.F150Y Missense 1/20 -
11-108138004-T-G ATM c.2573T>G p.F858C Missense 17/63 -
22-41523614-C-T EP300 c.1030C>T p.L344F Missense 4/31 -
8-133894843-C-T TG c.875C>T p.S292F Missense 7/48 -
3-185146566-C-A MAP3K13 c.197C>A p.T66K Missense 2/14 -
7-55210018-C-T EGFR c.128C>T p.T43I Missense 2/28 -
1-27100096-G-C ARID1A c.3892G>C p.G1298R Missense 16/20 -
5-112162891-C-A APC c.1495C>A p.R499= Synonymous 12/16 -
13-28623673-C-A FLT3 c.884G>T p.G295V Missense 8/24 -
22-41527473-C-A EP300 c.1364C>A p.T455N Missense 6/31 -
1-11298065-C-G MTOR c.2043G>C p.E681D Missense 13/58 -
13-25058871-TGGG-T PARP4 c.1366_1368delCCC p.P456del InFrameDeletion 12/34 -
8-133899033-TGGA-T TG c.1419_1421delAGG p.G474del InFrameDeletion 9/48 -
8-6357412-G-A MCPH1 c.2176G>A p.E726K Missense 12/14 -
X-53247055-T-G KDM5C c.445A>C p.I149L Missense 4/26 -
3-142281795-A-T ATR c.449T>A p.L150* Nonsense 4/47 -
13-25052368-G-T PARP4 c.1495C>A p.L499I Missense 13/34 -
5-176519758-C-T FGFR4 c.1030C>T p.Q344* Nonsense 8/18 -
X-70342403-G-T MED12 c.1294G>T p.G432* Nonsense 9/45 -
3-138478148-T-C PIK3CB c.38A>G p.D13G Missense 3/24 -
2-48026305-A-C MSH6 c.1183A>C p.T395P Missense 4/10 -
18-39617688-G-C PIK3C3 c.1872G>C p.K624N Missense 17/25 -
11-108216585-G-T ATM c.8534G>T p.W2845L Missense 58/63 -
17-29557887-C-A NF1 c.3141C>A p.D1047E Missense 24/58 -
5-112177556-G-T APC c.6265G>T p.E2089* Nonsense 16/16 -
12-46231295-G-T ARID2 c.1135G>T p.G379* Nonsense 10/21 -
17-37883698-C-A ERBB2 c.3310C>A p.H1104N Missense 26/27 -
13-25077787-G-A PARP4 c.128C>T p.P43L Missense 2/34 -
8-6338304-G-C MCPH1 c.2043G>C p.E681D Missense 11/14 -
17-37866696-G-T ERBB2 c.863G>T p.R288L Missense 7/27 -
19-11107001-G-T SMARCA4 c.1706G>T p.R569L Missense 10/35 -
19-11141440-G-T SMARCA4 c.3417G>T p.L1139= Synonymous 25/35 -
7-116339467-G-T MET c.329G>T p.G110V Missense 2/21 -
13-48941651-T-C RB1 c.961T>C p.Y321H Missense 10/27 -
15-43748676-C-G TP53BP1 c.2130G>C p.K710N Missense 12/28 -
17-1746097-G-T RPA1 c.34G>T p.A12S Missense 2/17 -
2-212587181-G-A ERBB4 c.820C>T p.Q274* Nonsense 7/28 -
8-128750507-C-A MYC c.44C>A p.T15K Missense 2/3 -
3-142215337-C-T ATR c.5764G>A p.E1922K Missense 34/47 -
13-25008597-A-G PARP4 c.4682T>C p.I1561T Missense 31/34 -
12-133249758-G-T POLE c.1465C>A p.P489T Missense 14/49 -
20-62844918-A-G MYT1 c.1549A>G p.K517E Missense 10/23 -
8-128750701-C-A MYC c.238C>A p.R80S Missense 2/3 -
20-62867972-C-T MYT1 c.2962C>T p.L988F Missense 20/23 -
12-133257789-G-C POLE c.139C>G p.R47G Missense 2/49 -
3-142188286-T-C ATR c.6445A>G p.I2149V Missense 38/47 -
14-45633573-G-T FANCM c.1593G>T p.Q531H Missense 10/23 -
13-25026658-C-A PARP4 c.2900G>T p.R967L Missense 24/34 -
12-133263861-C-A POLE c.41G>T p.G14V Missense 1/49 -
19-11113741-G-T SMARCA4 c.1849G>T p.V617L Missense 12/35 -
17-1782644-C-A RPA1 c.895C>A p.Q299K Missense 10/17 -
3-178947888-C-A PIK3CA c.2763C>A p.I921= Synonymous 19/21 -
20-62839434-GGAGGAA-G MYT1 c.903_908delAGAGGA p.E305_E306del InFrameDeletion 7/23 -
12-46123660-G-T ARID2 c.41G>T p.R14I Missense 1/21 -
4-55955128-C-A KDR c.3417G>T p.M1139I Missense 26/30 -
X-70346896-C-A MED12 c.2763C>A p.S921R Missense 20/45 -
19-11107215-G-T SMARCA4 c.1807G>T p.G603C Missense 11/35 -
19-11138554-C-A SMARCA4 c.3310C>A p.Q1104K Missense 24/35 -
17-1787116-G-C RPA1 c.1252G>C p.E418Q Missense 13/17 -
12-133219452-A-G POLE c.4682T>C p.L1561P Missense 36/49 -
5-68463841-C-T CCNB1 c.128C>T p.T43I Missense 2/9 -
19-11095964-C-A SMARCA4 c.238C>A p.H80N Missense 3/35 -
14-45628451-A-G FANCM c.1549A>G p.T517A Missense 9/23 -
X-53245319-C-A KDM5C c.718G>T p.G240W Missense 6/26 -
12-46230571-C-T ARID2 c.820C>T p.R274* Nonsense 8/21 -
17-1792132-G-T RPA1 c.1538G>T p.R513L Missense 14/17 -
17-29527495-A-G NF1 c.944A>G p.Q315R Missense 9/58 -
17-37872589-C-T ERBB2 c.1549C>T p.R517* Nonsense 13/27 -
12-46245363-G-T ARID2 c.3457G>T p.G1153C Missense 15/21 -
12-46211474-G-A ARID2 c.440G>A p.G147E Missense 5/21 -
17-41246845-T-C BRCA1 c.703A>G p.N235D Missense 10/23 -
13-32903598-C-T BRCA2 c.650C>T p.S217F Missense 8/27 -
15-43700242-A-ATGGGGGGGG TP53BP1 c.5644_5645insCCCCCCCCA p.V1882delinsAPPI MultiAAMissense 27/28 -
15-43700243-C-CGGGGGGGGT TP53BP1 c.5643_5644insACCCCCCCC p.L1881_V1882insTPP InFrameInsertion 27/28 -
17-37872589-CGA-TGT ERBB2 c.1549_1551delCGAinsTGT p.R517C Missense 13/27 -
17-59938822-C-T BRIP1 c.79G>A p.A27T Missense 2/20 -
7-26225102-G-A NFE2L3 c.1784G>A p.C595Y Missense 4/4 -
2-29551271-C-A ALK c.1359G>T p.Q453H Missense 6/29 -
2-48028282-A-C MSH6 c.3160A>C p.I1054L Missense 4/10 -
17-78897438-C-A RPTOR c.2773C>A p.R925= Synonymous 23/34 -
7-26224879-C-T NFE2L3 c.1561C>T p.Q521* Nonsense 4/4 -
3-156395850-C-A TIPARP c.364C>A p.P122T Missense 2/6 -
10-123274763-G-C FGFR2 c.1155C>G p.V385= Synonymous 9/18 -
2-48023050-G-C MSH6 c.475G>C p.A159P Missense 3/10 -
17-37884152-A-C ERBB2 c.3623A>C p.H1208P Missense 27/27 -
17-78896563-T-C RPTOR c.2560T>C p.S854P Missense 22/34 -
1-9781186-T-G PIK3CD c.1691T>G p.M564R Missense 14/24 -
20-30309799-A-C BCL2L1 c.223T>G p.L75V Missense 2/3 -
1-9775907-G-C PIK3CD c.371G>C p.G124A Missense 5/24 -
10-8106060-A-C GATA3 c.883A>C p.N295H Missense 4/6 -
19-18273833-T-C PIK3R2 c.1166T>C p.F389S Missense 10/16 -
10-8100780-A-C GATA3 c.754A>C p.R252= Synonymous 3/6 -
19-30313225-T-G CCNE1 c.919T>G p.F307V Missense 10/12 -
7-55221804-G-C EGFR c.848G>C p.G283A Missense 7/28 -
5-176636863-A-C NSD1 c.1463A>C p.D488A Missense 5/23 -
3-168812877-A-T MECOM c.3006T>A p.N1002K Missense 13/17 -
5-176562139-G-A NSD1 c.35G>A p.C12Y Missense 2/23 -
21-39755406-C-A ERG c.1359G>T p.W453C Missense 10/10 -
12-46245507-A-G ARID2 c.3601A>G p.I1201V Missense 15/21 -
19-11134290-G-T SMARCA4 c.2956G>T p.A986S Missense 20/35 -
17-59871053-C-A BRIP1 c.1378G>T p.D460Y Missense 10/20 -
5-112102078-G-T APC c.191G>T p.G64V Missense 3/16 -
9-80430637-A-G GNAQ c.371T>C p.F124S Missense 3/7 -
8-6338368-C-T MCPH1 c.2107C>T p.R703C Missense 11/14 -
5-112175306-G-T APC c.4015G>T p.G1339C Missense 16/16 -
19-11098597-A-T SMARCA4 c.1115A>T p.Y372F Missense 6/35 -
1-11190697-CGTGGTGGCGGCA-C MTOR c.5490_5501del12 p.T1834_T1837del InFrameDeletion 39/58 -
1-11190697-CCGT-C MTOR c.5500_5502delACG p.T1834del InFrameDeletion 39/58 -
11-108106436-T-C ATM c.371T>C p.I124T Missense 5/63 -
1-150550773-T-G MCL1 c.883A>C p.T295P Missense 2/3 -
19-11145653-G-T SMARCA4 c.4015G>T p.E1339* Nonsense 29/35 -
16-23646701-A-G PALB2 c.1166T>C p.L389P Missense 4/13 -
19-45867554-T-G ERCC2 c.754A>C p.T252P Missense 9/23 -
7-55223552-T-G EGFR c.919T>G p.C307G Missense 8/28 -
2-178095640-A-C NFE2L2 c.1691T>G p.V564G Missense 5/5 -
19-18271759-A-G PIK3R2 c.446A>G p.E149G Missense 4/16 -
5-176665503-C-T NSD1 c.4187C>T p.T1396M Missense 7/23 -
2-178095868-T-G NFE2L2 c.1463A>C p.E488A Missense 5/5 -
1-11307752-G-C MTOR c.1155C>G p.N385K Missense 8/58 -
17-78727913-C-T RPTOR c.758C>T p.P253L Missense 6/34 -
7-26192153-G-A NFE2L3 c.35G>A p.G12D Missense 1/4 -
17-63554296-T-G AXIN2 c.443A>C p.Q148P Missense 2/11 -
17-63533795-C-A AXIN2 c.1359G>T p.Q453H Missense 6/11 -
5-131945029-C-A RAD50 c.2977C>A p.H993N Missense 19/25 -
5-112103036-T-C APC c.371T>C p.V124A Missense 4/16 -
8-6296480-A-C MCPH1 c.443A>C p.D148A Missense 6/14 -
8-6302358-A-T MCPH1 c.1115A>T p.K372M Missense 8/14 -
5-112173338-A-G APC c.2047A>G p.T683A Missense 16/16 -
5-112173363-A-G APC c.2072A>G p.N691S Missense 16/16 -
2-190718673-A-C PMS1 c.831A>C p.R277= Synonymous 8/13 -
1-11273609-C-T MTOR c.3132G>A p.M1044I Missense 21/58 -
7-55214398-A-G EGFR c.524A>G p.N175S Missense 4/28 -
5-68464004-C-A CCNB1 c.197C>A p.A66E Missense 3/9 -
X-53245008-C-T KDM5C c.932G>A p.R311K Missense 7/26 -
15-43762193-C-G TP53BP1 c.1252G>C p.E418Q Missense 11/28 -
18-39567797-G-T PIK3C3 c.553G>T p.G185* Nonsense 5/25 -
5-131978009-G-C RAD50 c.3892G>C p.E1298Q Missense 25/25 -
15-43766931-C-A TP53BP1 c.1120G>T p.A374S Missense 10/28 -
18-39647380-C-T PIK3C3 c.2552C>T p.S851L Missense 24/25 -
14-45636170-G-T FANCM c.1806G>T p.Q602H Missense 11/23 -
4-55139790-T-C PDGFRA c.1451T>C p.V484A Missense 10/23 -
10-43613833-C-A RET c.2297C>A p.P766Q Missense 13/20 -
X-53226086-G-T KDM5C c.2763C>A p.L921= Synonymous 19/26 -
10-43604659-G-T RET c.1244G>T p.R415M Missense 6/20 -
1-11194472-C-A MTOR c.5182G>T p.A1728S Missense 37/58 -
7-55227874-C-G EGFR c.1341C>G p.S447= Synonymous 12/28 -
8-133880419-C-A TG c.127C>A p.L43M Missense 2/48 -
8-133900447-C-A TG c.2395C>A p.P799T Missense 10/48 -
14-45645576-A-T FANCM c.3619A>T p.R1207* Nonsense 14/23 -
4-55155249-G-T PDGFRA c.2848G>T p.V950L Missense 21/23 -
4-55127333-C-T PDGFRA c.121C>T p.L41= Synonymous 3/23 -
14-45605328-C-A FANCM c.94C>A p.P32T Missense 1/23 -
9-135798849-C-A TSC1 c.394G>T p.G132C Missense 6/23 -
17-29562765-G-T NF1 c.3845G>T p.S1282I Missense 28/58 -
6-152129346-T-C ESR1 c.299T>C p.L100P Missense 1/8 -
10-43607599-G-T RET c.1575G>T p.R525= Synonymous 8/20 -
9-135778000-C-A TSC1 c.2383G>T p.E795* Nonsense 18/23 -
17-59886042-T-A BRIP1 c.704A>T p.K235M Missense 7/20 -
1-243727132-C-A AKT3 c.838G>T p.D280Y Missense 10/14 -
2-29416692-C-A ALK c.4261G>T p.V1421F Missense 29/29 -
X-70352315-G-T MED12 c.4342G>T p.G1448W Missense 31/45 -
X-70344209-G-T MED12 c.1945G>T p.A649S Missense 13/45 -
X-70346321-A-T MED12 c.2672A>T p.D891V Missense 19/45 -
10-43617398-G-T RET c.2735G>T p.R912L Missense 16/20 -
19-10599954-G-C KEAP1 c.1622C>G p.T541R Missense 5/6 -
12-133233734-C-A POLE c.3570G>T p.E1190D Missense 29/49 -
10-43613911-G-A RET c.2375G>A p.G792E Missense 13/20 -
12-4554732-G-T FGF6 c.5C>A p.A2D Missense 1/3 -
19-52723055-G-T PPP2R1A c.1240G>T p.D414Y Missense 10/15 -
2-39251155-G-T SOS1 c.1198C>A p.L400M Missense 9/23 -
20-62836441-G-T MYT1 c.140G>T p.R47M Missense 5/23 -
17-33428272-G-T RAD51D c.851C>A p.A284E Missense 9/10 -
X-53223747-C-A KDM5C c.3612G>T p.L1204= Synonymous 23/26 -
X-76854919-T-C ATRX c.5917A>G p.T1973A Missense 25/35 -
2-212615373-A-G ERBB4 c.613T>C p.C205R Missense 5/28 -
11-108121564-T-C ATM c.1372T>C p.C458R Missense 10/63 -
20-62842604-G-A MYT1 c.1337G>A p.G446D Missense 8/23 -
12-25378676-C-G KRAS c.322G>C p.D108H Missense 4/5 -
2-212522506-C-T ERBB4 c.1919G>A p.G640D Missense 16/28 -
22-41537212-C-T EP300 c.2039C>T p.P680L Missense 10/31 -
22-41548315-A-G EP300 c.3103A>G p.T1035A Missense 16/31 -
9-133761011-C-A ABL1 c.3334C>A p.Q1112K Missense 11/11 -
13-28622494-C-T FLT3 c.1123G>A p.A375T Missense 9/24 -
16-68867284-G-A CDH1 c.2531G>A p.S844N Missense 16/16 -
8-90965483-T-A NBN c.1834A>T p.S612C Missense 11/16 -
4-55133532-A-C PDGFRA c.836A>C p.E279A Missense 6/23 -
8-90996767-G-A NBN c.23C>T p.A8V Missense 1/16 -
2-190719302-C-G PMS1 c.1304C>G p.A435G Missense 9/13 -
7-6043403-T-C PMS2 c.271A>G p.K91E Missense 4/15 -
2-212251761-C-CA ERBB4 c.3297_3297dupT p.E1100* Nonsense 27/28 -
17-37881338-AGG-CAT ERBB2 c.2530_2532delAGGinsCAT p.R844H Missense 21/27 -
17-29560142-A-T NF1 c.3619A>T p.R1207* Nonsense 27/58 -
2-212293190-C-T ERBB4 c.2662G>A p.A888T Missense 22/28 -
4-55151608-C-A PDGFRA c.2394C>A p.F798L Missense 17/23 -
22-22123570-C-G MAPK1 c.1006G>C p.D336H Missense 8/9 -
14-45605355-C-T FANCM c.121C>T p.P41S Missense 1/23 -
2-29541195-G-C ALK c.1622C>G p.A541G Missense 8/29 -
4-55127306-C-A PDGFRA c.94C>A p.P32T Missense 3/23 -
5-131973867-G-T RAD50 c.3570G>T p.K1190N Missense 23/25 -
7-55266497-G-T EGFR c.2789G>T p.G930V Missense 23/28 -
5-176524643-G-A FGFR4 c.2375G>A p.S792N Missense 18/18 -
19-10610316-C-A KEAP1 c.394G>T p.V132F Missense 2/6 -
11-108150267-C-A ATM c.3334C>A p.P1112T Missense 23/63 -
19-30313208-C-A CCNE1 c.902C>A p.A301D Missense 10/12 -
22-41523707-G-A EP300 c.1123G>A p.V375I Missense 4/31 -
20-62839789-G-T MYT1 c.1240G>T p.G414W Missense 7/23 -
5-131923333-A-C RAD50 c.836A>C p.K279T Missense 6/25 -
5-56155597-C-T MAP3K1 c.689C>T p.A230V Missense 3/20 -
11-108181041-A-G ATM c.5917A>G p.R1973G Missense 39/63 -
7-26224622-C-G NFE2L3 c.1304C>G p.S435C Missense 4/4 -
17-33428305-C-A RAD51D c.818G>T p.S273I Missense 9/10 -
3-51978171-A-G PARP3 c.271A>G p.I84V Missense 3/11 -
10-43606842-T-C RET c.1451T>C p.M484T Missense 7/20 -
16-68772278-C-A CDH1 c.127C>A p.R43= Synonymous 2/16 -
7-81350088-C-A HGF c.1244G>T p.W415L Missense 10/18 -
14-45650671-G-T FANCM c.4261G>T p.E1421* Nonsense 15/23 -
3-51981799-C-G PARP3 c.1341C>G p.F440L Missense 10/11 -
22-29130456-G-T CHEK2 c.254C>A p.P85H Missense 2/15 -
17-29553490-G-T NF1 c.2039G>T p.C680F Missense 18/58 -
17-78857243-T-A RPTOR c.1609T>A p.F537I Missense 15/34 -
1-162725005-T-A DDR2 c.477T>A p.I159= Synonymous 6/18 -
17-29661946-G-T NF1 c.5903G>T p.R1968L Missense 40/58 -
17-29653029-C-A NF1 c.5027C>A p.A1676E Missense 37/58 -
13-32905077-A-G BRCA2 c.703A>G p.N235D Missense 9/27 -
1-162740273-C-A DDR2 c.1475C>A p.P492Q Missense 12/18 -
5-80040391-C-A MSH3 c.1720C>A p.R574= Synonymous 12/24 -
17-29667614-T-A NF1 c.7013T>A p.L2338H Missense 47/58 -
17-41245314-T-A BRCA1 c.2234A>T p.E745V Missense 10/23 -
22-29130690-A-C CHEK2 c.20T>G p.V7G Missense 2/15 -
17-41246876-A-C BRCA1 c.672T>G p.A224= Synonymous 10/23 -
17-37871565-T-C ERBB2 c.1175T>C p.L392P Missense 10/27 -
17-37879579-A-C ERBB2 c.1954A>C p.T652P Missense 17/27 -
1-9781869-A-C PIK3CD c.2006A>C p.E669A Missense 16/24 -
17-63533853-T-G AXIN2 c.1301A>C p.D434A Missense 6/11 -
17-63554598-T-G AXIN2 c.141A>C p.K47N Missense 2/11 -
17-63554704-T-G AXIN2 c.35A>C p.D12A Missense 2/11 -
22-29092956-A-C CHEK2 c.1028T>G p.I343S Missense 10/15 -
1-9781889-A-C PIK3CD c.2026A>C p.T676P Missense 16/24 -
17-63554425-A-G AXIN2 c.314T>C p.V105A Missense 2/11 -
11-69456271-A-G CCND1 c.190A>G p.M64V Missense 1/5 -
13-22246314-A-C FGF9 c.263A>C p.D88A Missense 1/3 -
19-4123868-A-C MAP2K2 c.5T>G p.L2R Missense 1/11 -
13-22275453-A-G FGF9 c.506A>G p.D169G Missense 3/3 -
16-2106703-T-C TSC2 c.707T>C p.L236P Missense 8/42 -
16-2110759-T-G TSC2 c.1064T>G p.V355G Missense 11/42 -
16-2133744-T-C TSC2 c.3932T>C p.L1311P Missense 33/42 -
X-53247475-G-C KDM5C c.334C>G p.L112V Missense 3/26 -
X-70356476-A-C MED12 c.5371A>C p.K1791Q Missense 37/45 -
12-133252733-T-G POLE c.967A>C p.T323P Missense 10/49 -
12-133252735-A-G POLE c.965T>C p.F322S Missense 10/49 -
X-53226151-G-T KDM5C c.2698C>A p.L900I Missense 19/26 -
5-80064808-GT-AA MSH3 c.2239_2240delinsAA p.V747K Missense 15/24 -
20-31023321-A-C ASXL1 c.2806A>C p.T936P Missense 13/13 -
20-31019468-A-C ASXL1 c.965A>C p.E322A Missense 10/13 -
13-25064961-T-G PARP4 c.1059A>C p.I353= Synonymous 10/34 -
12-133257204-T-G POLE c.274A>C p.S92R Missense 3/49 -
20-30946592-A-C ASXL1 c.14A>C p.Q5P Missense 1/13 -
19-1220638-T-C STK11 c.656T>C p.F219S Missense 5/10 -
10-43615572-A-C RET c.2651A>C p.E884A Missense 15/20 -
19-11138519-T-C SMARCA4 c.3275T>C p.L1092P Missense 24/35 -
5-80074539-C-CA MSH3 c.2320_2320dupA p.T774Nfs*29 SpliceAcceptorInsertion 17/24 -
19-1226498-GCCT-G STK11 c.1157_1159delTCC p.L386del InFrameDeletion 9/10 -
5-176707587-G-GCCCCCCCCA NSD1 c.5644_5645insCCCCCCCCA p.V1882delinsAPPI MultiAAMissense 18/23 -
12-133225570-A-C POLE c.4094T>G p.V1365G Missense 32/49 -
17-63532573-T-G AXIN2 c.2006A>C p.H669P Missense 8/11 -
13-28636118-A-C FLT3 c.254T>G p.V85G Missense 3/24 -
2-58431309-C-G FANCL c.427G>C p.A143P Missense 6/14 -
8-48868487-T-G PRKDC c.346A>C p.T116P Missense 4/87 -
13-28623797-T-C FLT3 c.857A>G p.E286G Missense 7/24 -
17-37866367-T-G ERBB2 c.672T>G p.C224W Missense 6/27 -
13-113897449-A-C CUL4A c.1203A>C p.R401S Missense 11/20 -
12-133218240-T-G POLE c.5371A>C p.T1791P Missense 39/49 -
15-43771611-T-G TP53BP1 c.772A>C p.N258H Missense 7/28 -
13-22246241-A-G FGF9 c.190A>G p.R64G Missense 1/3 -
2-58453880-C-A FANCL c.256G>T p.E86* Nonsense 4/14 -
12-44180345-A-C IRAK4 c.1332A>C p.R444S Missense 11/12 -
10-43596107-A-C RET c.274A>C p.T92P Missense 2/20 -
19-11132435-A-C SMARCA4 c.2651A>C p.H884P Missense 19/35 -
16-89862355-T-G FANCA c.965A>C p.H322P Missense 11/43 -
13-28609665-T-G FLT3 c.1564A>C p.T522P Missense 12/24 -
7-26224445-C-A NFE2L3 c.1127C>A p.T376K Missense 4/4 -
1-9782388-T-G PIK3CD c.2321T>G p.V774G Missense 18/24 -
5-176638098-C-A NSD1 c.2698C>A p.P900T Missense 5/23 -
3-185167766-G-T MAP3K13 c.1089G>T p.W363C Missense 6/14 -
22-24134000-T-G SMARCB1 c.151T>G p.W51G Missense 2/9 -
4-1795695-G-T FGFR3 c.34G>T p.V12L Missense 2/18 -
13-32907090-C-A BRCA2 c.1475C>A p.S492Y Missense 10/27 -
1-27099035-A-T ARID1A c.3451A>T p.S1151C Missense 13/20 -
4-1807479-C-T FGFR3 c.1648C>T p.P550S Missense 13/18 -
13-25077880-C-G PARP4 c.35G>C p.C12S Missense 2/34 -
8-90958391-T-C NBN c.2047A>G p.K683E Missense 13/16 -
13-25068770-G-A PARP4 c.682C>T p.L228= Synonymous 7/34 -
4-55124969-G-C PDGFRA c.34G>C p.G12R Missense 2/23 -
4-55151610-C-T PDGFRA c.2396C>T p.T799I Missense 17/23 -
X-70349190-C-A MED12 c.3602C>A p.S1201Y Missense