PMID: 28797232

Prognostic significance of BRAF and NRAS mutations in melanoma: a German study from routine care.

BMC cancer
Heppt, Markus V MV, Siepmann, Timo T, Engel, Jutta J, Schubert-Fritschle, Gabriele G, Eckel, Renate R, Mirlach, Laura L, Kirchner, Thomas T, Jung, Andreas A, Gesierich, Anja A, Ruzicka, Thomas T, Flaig, Michael J MJ, Berking, Carola C
2017-08-10

8 variants were identified in this publication


Variant ID Gene cDNA Protein Consequence Exon Intron
7-140453145-AG-GA BRAF c.1789_1790delCTinsTC p.L597S Missense 15/18 -
1-115256535-G-T NRAS c.176C>A p.A59D Missense 3/7 -
7-140453128-G-A BRAF c.1807C>T p.R603* Nonsense 15/18 -
7-140453185-G-A BRAF c.1750C>T p.L584F Missense 15/18 -
7-140453141-A-T BRAF c.1794T>A p.A598= Synonymous 15/18 -
7-140453141-A-G BRAF c.1794T>C p.A598= Synonymous 15/18 -
7-140453141-A-C BRAF c.1794T>G p.A598= Synonymous 15/18 -
1-115256529-TG-AC NRAS c.181_182delCAinsGT p.Q61V Missense 3/7 -