PMID: 30792639

Beyond KRAS: Practical Molecular Targets in Pancreatic Adenocarcinoma.

Case reports in oncology
Grinshpun, Albert A, Zarbiv, Yonaton Y, Roszik, Jason J, Subbiah, Vivek V, Hubert, Ayala A
2019

22 variants were identified in this publication


Variant ID Gene cDNA Protein Consequence Exon Intron
10-43620366-C-T RET c.2975C>T p.P992L Missense 18/20 -
10-43613844-C-T RET c.2308C>T p.R770* Nonsense 13/20 -
7-140453134-TTCA-T BRAF c.1799_1801delTGA p.V600_K601delinsE MultiAAMissense 15/18 -
7-140477838-TAGG-T BRAF c.1468_1470delCCT p.P490del InFrameDeletion 12/18 -
7-140453141-A-C BRAF c.1794T>G p.A598= Synonymous 15/18 -
7-140481397-C-T BRAF c.1411G>A p.V471I Missense 11/18 -
7-140453141-A-T BRAF c.1794T>A p.A598= Synonymous 15/18 -
7-140453141-A-G BRAF c.1794T>C p.A598= Synonymous 15/18 -
10-43623629-G-C RET c.3257G>C p.G1086A Missense 20/20 -
10-43596002-C-T RET c.169C>T p.R57W Missense 2/20 -
7-140481423-C-G BRAF c.1385G>C p.R462T Missense 11/18 -
10-43615116-C-T RET c.2530C>T p.R844W Missense 14/20 -
10-43596003-G-A RET c.170G>A p.R57Q Missense 2/20 -
7-140477848-AC-GA BRAF c.1459_1460delGTinsTC p.V487S Missense 12/18 -
7-140449182-A-G BRAF c.1897T>C p.Y633H Missense 16/18 -
10-43622039-C-T RET c.3056C>T p.A1019V Missense 19/20 -
10-43601941-T-C RET c.985T>C p.F329L Missense 5/20 -
10-43601943-C-A RET c.987C>A p.F329L Missense 5/20 -
10-43601943-C-G RET c.987C>G p.F329L Missense 5/20 -
10-43613888-C-T RET c.2352C>T p.H784= Synonymous 13/20 -
10-43623580-C-T RET c.3208C>T p.P1070S Missense 20/20 -
10-43612162-C-A RET c.2267C>A p.A756D Missense 12/20 -