PMID: 31034466

Finding driver mutations in cancer: Elucidating the role of background mutational processes.

PLoS computational biology

Brown, Anna-Leigh AL, Li, Minghui M, Goncearenco, Alexander A, Panchenko, Anna R AR

2019-04

5520 variants were identified in this publication

Variant ID	Gene	cDNA	Protein	Consequence	Exon	Intron
12-133219309-G-A	POLE	c.4735C>T	p.R1579C	Missense	37/49	-
12-133256161-C-T	POLE	c.500G>A	p.R167K	Missense	6/49	-
12-133257861-C-T	POLE	c.67G>A	p.D23N	Missense	2/49	-
12-133250204-A-G	POLE	c.1316T>C	p.L439P	Missense	13/49	-
12-133256116-T-C	POLE	c.545A>G	p.H182R	Missense	6/49	-
5-67592114-G-A	PIK3R1	c.1930G>A	p.G644S	Missense	15/16	-
17-7579341-A-G	TP53	c.346T>C	p.S116P	Missense	4/11	-
17-7573988-C-A	TP53	c.1039G>T	p.A347S	Missense	10/11	-
12-133256622-C-T	POLE	c.341G>A	p.R114Q	Missense	5/49	-
17-7579395-G-C	TP53	c.292C>G	p.P98A	Missense	4/11	-
17-7579315-G-C	TP53	c.372C>G	p.C124W	Missense	4/11	-
17-7578385-C-A	TP53	c.545G>T	p.C182F	Missense	5/11	-
7-140477811-T-A	BRAF	c.1497A>T	p.K499N	Missense	12/18	-
3-138374308-C-T	PIK3CB	c.3136G>A	p.D1046N	Missense	24/24	-
7-140477798-C-T	BRAF	c.1510G>A	p.V504I	Missense	12/18	-
7-140549946-C-T	BRAF	c.205G>A	p.G69S	Missense	2/18	-
3-138417859-C-T	PIK3CB	c.1660G>A	p.E554K	Missense	13/24	-
3-138423330-A-C	PIK3CB	c.1536T>G	p.I512M	Missense	12/24	-
3-138374281-T-C	PIK3CB	c.3163A>G	p.T1055A	Missense	24/24	-
3-138474789-C-T	PIK3CB	c.204G>A	p.M68I	Missense	4/24	-
3-138474789-C-A	PIK3CB	c.204G>T	p.M68I	Missense	4/24	-
3-138461602-A-G	PIK3CB	c.419T>C	p.L140S	Missense	5/24	-
3-138413736-A-G	PIK3CB	c.1784T>C	p.L595P	Missense	14/24	-
3-138402591-G-T	PIK3CB	c.2354C>A	p.P785H	Missense	18/24	-
3-138417775-A-G	PIK3CB	c.1744T>C	p.W582R	Missense	13/24	-
3-138431123-A-T	PIK3CB	c.1326T>A	p.N442K	Missense	10/24	-
3-138402532-T-C	PIK3CB	c.2413A>G	p.K805E	Missense	18/24	-
3-138431064-C-G	PIK3CB	c.1385G>C	p.W462S	Missense	10/24	-
3-138376532-C-G	PIK3CB	c.2942G>C	p.R981P	Missense	22/24	-
3-138400825-C-T	PIK3CB	c.2488G>A	p.A830T	Missense	19/24	-
3-138456596-C-G	PIK3CB	c.754G>C	p.G252R	Missense	6/24	-
2-29455209-A-G	ALK	c.2593T>C	p.S865P	Missense	15/29	-
17-7578220-T-A	TP53	c.629A>T	p.N210I	Missense	6/11	-
7-128846357-G-A	SMO	c.1193G>A	p.R398Q	Missense	6/12	-
2-29474042-G-T	ALK	c.2133C>A	p.S711R	Missense	12/29	-
12-133219135-G-A	POLE	c.4909C>T	p.L1637F	Missense	37/49	-
19-50905945-G-A	POLD1	c.917G>A	p.R306H	Missense	8/27	-
19-50918754-G-A	POLD1	c.2624G>A	p.R875H	Missense	21/27	-
19-50912397-C-A	POLD1	c.1911C>A	p.F637L	Missense	16/27	-
19-50912867-G-A	POLD1	c.2098G>A	p.V700I	Missense	17/27	-
19-50910659-G-A	POLD1	c.1762G>A	p.E588K	Missense	14/27	-
19-50912052-G-A	POLD1	c.1786G>A	p.V596I	Missense	15/27	-
19-50919882-G-A	POLD1	c.2969G>A	p.R990H	Missense	24/27	-
19-50912082-C-G	POLD1	c.1816C>G	p.L606V	Missense	15/27	-
19-50921177-C-G	POLD1	c.3297C>G	p.F1099L	Missense	27/27	-
19-50905494-C-T	POLD1	c.622C>T	p.P208S	Missense	6/27	-
19-50902643-C-T	POLD1	c.218C>T	p.S73L	Missense	3/27	-
12-133214669-C-T	POLE	c.5609G>A	p.R1870H	Missense	41/49	-
12-133245305-C-T	POLE	c.1942G>A	p.E648K	Missense	18/49	-
12-133226032-G-T	POLE	c.3865C>A	p.R1289S	Missense	31/49	-
12-133248899-C-T	POLE	c.1696G>A	p.A566T	Missense	16/49	-
12-133236001-G-A	POLE	c.3155C>T	p.T1052M	Missense	26/49	-
12-133219579-G-A	POLE	c.4555C>T	p.R1519C	Missense	36/49	-
12-133218913-G-A	POLE	c.5023C>T	p.R1675C	Missense	38/49	-
12-133233813-G-A	POLE	c.3491C>T	p.P1164L	Missense	29/49	-
12-133249242-G-A	POLE	c.1657C>T	p.R553C	Missense	15/49	-
12-133252767-C-G	POLE	c.933G>C	p.E311D	Missense	10/49	-
12-133218876-G-A	POLE	c.5060C>T	p.S1687F	Missense	38/49	-
7-140550005-T-A	BRAF	c.146A>T	p.N49I	Missense	2/18	-
7-140482873-C-A	BRAF	c.1262G>T	p.G421V	Missense	10/18	-
7-140501295-G-C	BRAF	c.777C>G	p.F259L	Missense	6/18	-
19-41745210-T-C	AXL	c.1276T>C	p.W426R	Missense	9/20	-
19-41745202-T-A	AXL	c.1268T>A	p.L423Q	Missense	9/20	-
19-41726703-A-G	AXL	c.248A>G	p.Q83R	Missense	2/20	-
19-41745172-G-T	AXL	c.1238G>T	p.G413V	Missense	9/20	-
5-67588167-T-A	PIK3R1	c.997T>A	p.W333R	Missense	8/16	-
1-9776649-A-G	PIK3CD	c.752A>G	p.Y251C	Missense	6/24	-
1-9780920-C-T	PIK3CD	c.1642C>T	p.R548W	Missense	13/24	-
1-9770571-G-A	PIK3CD	c.58G>A	p.V20I	Missense	3/24	-
1-9782591-C-T	PIK3CD	c.2353C>T	p.R785W	Missense	19/24	-
1-9778917-G-A	PIK3CD	c.1186G>A	p.A396T	Missense	9/24	-
1-9778764-G-A	PIK3CD	c.1033G>A	p.A345T	Missense	9/24	-
1-9783302-C-T	PIK3CD	c.2546C>T	p.A849V	Missense	20/24	-
1-9784371-T-A	PIK3CD	c.2756T>A	p.F919Y	Missense	22/24	-
1-9784410-T-G	PIK3CD	c.2795T>G	p.F932C	Missense	22/24	-
5-67589591-T-C	PIK3R1	c.1354T>C	p.Y452H	Missense	11/16	-
X-47430737-G-C	ARAF	c.1702G>C	p.E568Q	Missense	16/16	-
19-50910352-C-T	POLD1	c.1607C>T	p.A536V	Missense	13/27	-
7-128845086-G-A	SMO	c.580G>A	p.E194K	Missense	3/12	-
3-138409876-G-A	PIK3CB	c.2002C>T	p.R668W	Missense	15/24	-
3-30713244-G-A	TGFBR2	c.569G>A	p.R190H	Missense	4/7	-
19-50910258-C-T	POLD1	c.1513C>T	p.R505C	Missense	13/27	-
19-50917086-G-A	POLD1	c.2338G>A	p.D780N	Missense	19/27	-
19-50912828-G-C	POLD1	c.2059G>C	p.D687H	Missense	17/27	-
19-50905073-C-T	POLD1	c.355C>T	p.R119C	Missense	4/27	-
19-50912130-C-T	POLD1	c.1864C>T	p.L622F	Missense	15/27	-
19-50905094-C-T	POLD1	c.376C>T	p.R126C	Missense	4/27	-
19-50905596-G-A	POLD1	c.724G>A	p.A242T	Missense	6/27	-
19-50910347-G-T	POLD1	c.1602G>T	p.E534D	Missense	13/27	-
19-50909464-G-T	POLD1	c.1268G>T	p.R423L	Missense	11/27	-
19-50918798-G-A	POLD1	c.2668G>A	p.A890T	Missense	21/27	-
19-50909469-G-A	POLD1	c.1273G>A	p.A425T	Missense	11/27	-
19-50905585-C-T	POLD1	c.713C>T	p.T238M	Missense	6/27	-
19-50916999-G-A	POLD1	c.2251G>A	p.V751M	Missense	19/27	-
12-133233987-C-T	POLE	c.3407G>A	p.R1136Q	Missense	28/49	-
12-133244163-G-A	POLE	c.2245C>T	p.R749W	Missense	20/49	-
12-133215721-G-A	POLE	c.5542C>T	p.L1848F	Missense	40/49	-
12-133219907-C-T	POLE	c.4454G>A	p.R1485H	Missense	35/49	-
12-133225540-G-A	POLE	c.4124C>T	p.A1375V	Missense	32/49	-
12-133238194-C-T	POLE	c.2783G>A	p.S928N	Missense	24/49	-
12-133226445-G-A	POLE	c.3613C>T	p.P1205S	Missense	30/49	-
12-133245420-T-C	POLE	c.1900A>G	p.I634V	Missense	17/49	-
12-133218969-G-A	POLE	c.4967C>T	p.P1656L	Missense	38/49	-
12-133242017-G-A	POLE	c.2339C>T	p.S780L	Missense	21/49	-
12-133218344-A-T	POLE	c.5267T>A	p.I1756N	Missense	39/49	-
12-133250163-G-C	POLE	c.1357C>G	p.Q453E	Missense	13/49	-
12-133245047-G-C	POLE	c.2068C>G	p.L690V	Missense	19/49	-
12-133215796-G-A	POLE	c.5467C>T	p.R1823C	Missense	40/49	-
12-133236002-T-C	POLE	c.3154A>G	p.T1052A	Missense	26/49	-
12-133250174-G-A	POLE	c.1346C>T	p.T449M	Missense	13/49	-
12-133226345-C-A	POLE	c.3713G>T	p.S1238I	Missense	30/49	-
12-133252024-C-T	POLE	c.1186G>A	p.E396K	Missense	12/49	-
12-133219305-C-T	POLE	c.4739G>A	p.R1580Q	Missense	37/49	-
19-50918795-C-T	POLD1	c.2665C>T	p.R889C	Missense	21/27	-
12-133245002-G-A	POLE	c.2113C>T	p.R705W	Missense	19/49	-
3-138402579-A-C	PIK3CB	c.2366T>G	p.V789G	Missense	18/24	-
5-67590988-T-G	PIK3R1	c.1581T>G	p.N527K	Missense	13/16	-
5-67590988-T-A	PIK3R1	c.1581T>A	p.N527K	Missense	13/16	-
12-133238183-C-T	POLE	c.2794G>A	p.E932K	Missense	24/49	-
12-133249755-C-T	POLE	c.1468G>A	p.D490N	Missense	14/49	-
3-138453640-G-A	PIK3CB	c.808C>T	p.R270W	Missense	7/24	-
7-128851557-C-T	SMO	c.1882C>T	p.R628W	Missense	11/12	-
12-133215786-C-T	POLE	c.5477G>A	p.R1826Q	Missense	40/49	-
9-98224161-C-T	PTCH1	c.2680G>A	p.D894N	Missense	16/24	-
12-133256154-C-G	POLE	c.507G>C	p.E169D	Missense	6/49	-
12-133256154-C-A	POLE	c.507G>T	p.E169D	Missense	6/49	-
19-50918196-C-T	POLD1	c.2513C>T	p.P838L	Missense	20/27	-
12-133209035-T-C	POLE	c.6196A>G	p.I2066V	Missense	45/49	-
12-133245462-G-A	POLE	c.1858C>T	p.P620S	Missense	17/49	-
19-50917075-G-A	POLD1	c.2327G>A	p.R776Q	Missense	19/27	-
19-50902699-G-A	POLD1	c.274G>A	p.E92K	Missense	3/27	-
19-50912089-C-T	POLD1	c.1823C>T	p.P608L	Missense	15/27	-
19-50912813-C-T	POLD1	c.2044C>T	p.R682W	Missense	17/27	-
12-133252337-C-G	POLE	c.1090G>C	p.G364R	Missense	11/49	-
19-50910265-G-A	POLD1	c.1520G>A	p.R507H	Missense	13/27	-
19-50917060-C-T	POLD1	c.2312C>T	p.A771V	Missense	19/27	-
12-133233948-G-A	POLE	c.3446C>T	p.A1149V	Missense	28/49	-
12-133220131-G-A	POLE	c.4306C>T	p.R1436W	Missense	34/49	-
12-133219288-C-T	POLE	c.4756G>A	p.A1586T	Missense	37/49	-
19-50905772-G-A	POLD1	c.820G>A	p.A274T	Missense	7/27	-
19-50912134-G-A	POLD1	c.1868G>A	p.R623Q	Missense	15/27	-
12-133233829-G-A	POLE	c.3475C>T	p.P1159S	Missense	29/49	-
17-37863275-C-T	ERBB2	c.106C>T	p.P36S	Missense	2/27	-
12-133218275-G-A	POLE	c.5336C>T	p.P1779L	Missense	39/49	-
12-133237689-G-A	POLE	c.2926C>T	p.R976C	Missense	25/49	-
12-133241046-G-A	POLE	c.2471C>T	p.A824V	Missense	22/49	-
12-133220142-G-A	POLE	c.4295C>T	p.P1432L	Missense	34/49	-
12-133208957-C-T	POLE	c.6274G>A	p.G2092S	Missense	45/49	-
12-133245474-G-A	POLE	c.1846C>T	p.R616C	Missense	17/49	-
12-133256616-A-G	POLE	c.347T>C	p.V116A	Missense	5/49	-
17-7577087-G-T	TP53	c.851C>A	p.T284K	Missense	8/11	-
12-133201381-T-C	POLE	c.6763A>G	p.I2255V	Missense	49/49	-
17-7578424-A-T	TP53	c.506T>A	p.M169K	Missense	5/11	-
12-133250279-T-C	POLE	c.1241A>G	p.D414G	Missense	13/49	-
12-133209044-A-G	POLE	c.6187T>C	p.F2063L	Missense	45/49	-
12-133209042-G-T	POLE	c.6189C>A	p.F2063L	Missense	45/49	-
12-133209042-G-C	POLE	c.6189C>G	p.F2063L	Missense	45/49	-
12-133220107-C-G	POLE	c.4330G>C	p.V1444L	Missense	34/49	-
12-133254166-C-T	POLE	c.718G>A	p.V240M	Missense	7/49	-
19-50910297-C-A	POLD1	c.1552C>A	p.L518M	Missense	13/27	-
12-133201291-C-A	POLE	c.6853G>T	p.G2285C	Missense	49/49	-
19-50909485-A-G	POLD1	c.1289A>G	p.N430S	Missense	11/27	-
19-50920510-G-A	POLD1	c.3202G>A	p.D1068N	Missense	26/27	-
12-133225983-C-T	POLE	c.3914G>A	p.G1305E	Missense	31/49	-
12-133225531-C-T	POLE	c.4133G>A	p.G1378D	Missense	32/49	-
12-133245516-C-T	POLE	c.1804G>A	p.E602K	Missense	17/49	-
12-133226080-G-A	POLE	c.3817C>T	p.R1273W	Missense	31/49	-
12-133202818-G-A	POLE	c.6416C>T	p.S2139F	Missense	46/49	-
5-67588167-T-C	PIK3R1	c.997T>C	p.W333R	Missense	8/16	-
12-133252342-T-C	POLE	c.1085A>G	p.Y362C	Missense	11/49	-
12-133252680-C-G	POLE	c.1020G>C	p.E340D	Missense	10/49	-
12-133240590-C-G	POLE	c.2706G>C	p.K902N	Missense	23/49	-
12-133240590-C-A	POLE	c.2706G>T	p.K902N	Missense	23/49	-
12-133252680-C-A	POLE	c.1020G>T	p.E340D	Missense	10/49	-
8-38285945-G-A	FGFR1	c.367C>T	p.P123S	Missense	4/18	-
19-50910390-C-T	POLD1	c.1645C>T	p.R549C	Missense	13/27	-
6-152419976-C-T	ESR1	c.1663C>T	p.R555C	Missense	8/8	-
17-37864781-C-T	ERBB2	c.433C>T	p.L145F	Missense	3/27	-
13-28919607-G-A	FLT1	c.2330C>T	p.T777I	Missense	16/30	-
12-133252054-C-T	POLE	c.1156G>A	p.E386K	Missense	12/49	-
19-50910427-G-A	POLD1	c.1682G>A	p.R561Q	Missense	13/27	-
19-50912864-T-A	POLD1	c.2095T>A	p.S699T	Missense	17/27	-
12-133220548-G-A	POLE	c.4165C>T	p.P1389S	Missense	33/49	-
12-133226438-G-A	POLE	c.3620C>T	p.P1207L	Missense	30/49	-
12-133240624-G-A	POLE	c.2672C>T	p.S891F	Missense	23/49	-
3-12650363-A-T	RAF1	c.483T>A	p.N161K	Missense	5/17	-
3-12660099-C-G	RAF1	c.122G>C	p.R41P	Missense	2/17	-
19-50905780-G-C	POLD1	c.828G>C	p.R276S	Missense	7/27	-
19-50905780-G-T	POLD1	c.828G>T	p.R276S	Missense	7/27	-
3-12660099-C-A	RAF1	c.122G>T	p.R41L	Missense	2/17	-
17-7578379-T-A	TP53	c.551A>T	p.D184V	Missense	5/11	-
17-7579467-C-T	TP53	c.220G>A	p.A74T	Missense	4/11	-
17-7579451-G-C	TP53	c.236C>G	p.A79G	Missense	4/11	-
17-7573937-C-G	TP53	c.1090G>C	p.A364P	Missense	10/11	-
17-7579572-C-G	TP53	c.115G>C	p.A39P	Missense	4/11	-
17-7579862-T-G	TP53	c.51A>C	p.E17D	Missense	2/11	-
17-7579862-T-A	TP53	c.51A>T	p.E17D	Missense	2/11	-
17-7572954-G-T	TP53	c.1155C>A	p.F385L	Missense	11/11	-
17-7572954-G-C	TP53	c.1155C>G	p.F385L	Missense	11/11	-
17-7579526-A-T	TP53	c.161T>A	p.F54Y	Missense	4/11	-
17-7576862-G-T	TP53	c.984C>A	p.F328L	Missense	9/11	-
17-7576862-G-C	TP53	c.984C>G	p.F328L	Missense	9/11	-
17-7578178-T-A	TP53	c.671A>T	p.E224V	Missense	6/11	-
17-7579713-T-G	TP53	c.83A>C	p.E28A	Missense	3/11	-
17-7578256-T-A	TP53	c.593A>T	p.E198V	Missense	6/11	-
17-7578397-T-C	TP53	c.533A>G	p.H178R	Missense	5/11	-
17-7577033-C-A	TP53	c.905G>T	p.G302V	Missense	8/11	-
17-7577147-A-T	TP53	c.791T>A	p.L264Q	Missense	8/11	-
17-7577052-G-C	TP53	c.886C>G	p.H296D	Missense	8/11	-
17-7579559-A-G	TP53	c.128T>C	p.L43S	Missense	4/11	-
17-7577134-G-C	TP53	c.804C>G	p.N268K	Missense	8/11	-
17-7577566-T-G	TP53	c.715A>C	p.N239H	Missense	7/11	-
17-7579443-G-A	TP53	c.244C>T	p.P82S	Missense	4/11	-
17-7578274-T-G	TP53	c.575A>C	p.Q192P	Missense	6/11	-
17-7576896-T-A	TP53	c.950A>T	p.Q317L	Missense	9/11	-
17-7578409-C-G	TP53	c.521G>C	p.R174T	Missense	5/11	-
17-7576907-G-C	TP53	c.939C>G	p.S313R	Missense	9/11	-
17-7574024-G-C	TP53	c.1003C>G	p.R335G	Missense	10/11	-
17-7576907-G-T	TP53	c.939C>A	p.S313R	Missense	9/11	-
17-7577499-C-A	TP53	c.782G>T	p.S261I	Missense	7/11	-
17-7577500-T-C	TP53	c.781A>G	p.S261G	Missense	7/11	-
17-7578376-C-G	TP53	c.554G>C	p.S185T	Missense	5/11	-
17-7577500-T-A	TP53	c.781A>T	p.S261C	Missense	7/11	-
17-7574002-C-A	TP53	c.1025G>T	p.R342L	Missense	10/11	-
17-7579870-T-G	TP53	c.43A>C	p.S15R	Missense	2/11	-
17-7578512-T-C	TP53	c.418A>G	p.T140A	Missense	5/11	-
17-7578512-T-G	TP53	c.418A>C	p.T140P	Missense	5/11	-
17-7578421-G-T	TP53	c.509C>A	p.T170K	Missense	5/11	-
17-7576861-T-A	TP53	c.985A>T	p.T329S	Missense	9/11	-
6-152332893-G-T	ESR1	c.1199G>T	p.G400V	Missense	5/8	-
17-7578493-C-A	TP53	c.437G>T	p.W146L	Missense	5/11	-
7-55210015-G-A	EGFR	c.125G>A	p.G42D	Missense	2/28	-
3-12660106-G-C	RAF1	c.115C>G	p.Q39E	Missense	2/17	-
19-50921110-C-T	POLD1	c.3230C>T	p.P1077L	Missense	27/27	-
12-133219489-G-A	POLE	c.4645C>T	p.P1549S	Missense	36/49	-
X-47428992-C-T	ARAF	c.1355C>T	p.T452I	Missense	13/16	-
7-140481388-C-T	BRAF	c.1420G>A	p.G474R	Missense	11/18	-
7-140481388-C-G	BRAF	c.1420G>C	p.G474R	Missense	11/18	-
19-50920465-C-T	POLD1	c.3157C>T	p.R1053C	Missense	26/27	-
3-12633235-C-T	RAF1	c.1165G>A	p.A389T	Missense	11/17	-
17-7573981-T-A	TP53	c.1046A>T	p.E349V	Missense	10/11	-
7-140439713-G-A	BRAF	c.2026C>T	p.P676S	Missense	17/18	-
17-41245136-C-A	BRCA1	c.2412G>T	p.Q804H	Missense	10/23	-
17-7579430-G-T	TP53	c.257C>A	p.A86E	Missense	4/11	-
19-50905567-G-A	POLD1	c.695G>A	p.R232H	Missense	6/27	-
12-133252765-A-G	POLE	c.935T>C	p.I312T	Missense	10/49	-
19-50917041-G-A	POLD1	c.2293G>A	p.V765M	Missense	19/27	-
17-37879838-G-T	ERBB2	c.2133G>T	p.Q711H	Missense	18/27	-
17-37879838-G-C	ERBB2	c.2133G>C	p.Q711H	Missense	18/27	-
3-30732969-C-A	TGFBR2	c.1582C>A	p.R528S	Missense	7/7	-
19-50909463-C-T	POLD1	c.1267C>T	p.R423C	Missense	11/27	-
19-50921157-G-A	POLD1	c.3277G>A	p.E1093K	Missense	27/27	-
17-41267770-G-A	BRCA1	c.107C>T	p.S36F	Missense	3/23	-
13-32944694-G-T	BRCA2	c.8487G>T	p.Q2829H	Missense	19/27	-
3-138409870-T-A	PIK3CB	c.2008A>T	p.I670L	Missense	15/24	-
4-55127303-C-T	PDGFRA	c.91C>T	p.L31F	Missense	3/23	-
12-133256086-G-A	POLE	c.575C>T	p.S192F	Missense	6/49	-
19-50918796-G-A	POLD1	c.2666G>A	p.R889H	Missense	21/27	-
12-133202244-G-A	POLE	c.6644C>T	p.T2215I	Missense	47/49	-
12-133225908-G-A	POLE	c.3989C>T	p.P1330L	Missense	31/49	-
12-133244153-G-A	POLE	c.2255C>T	p.S752F	Missense	20/49	-
12-133244975-C-T	POLE	c.2140G>A	p.E714K	Missense	19/49	-
19-50905264-C-T	POLD1	c.472C>T	p.P158S	Missense	5/27	-
19-50906366-C-T	POLD1	c.1027C>T	p.R343C	Missense	9/27	-
19-50906835-C-T	POLD1	c.1223C>T	p.S408F	Missense	10/27	-
19-50912133-C-T	POLD1	c.1867C>T	p.R623W	Missense	15/27	-
19-50902172-C-T	POLD1	c.64C>T	p.L22F	Missense	2/27	-
19-50906828-C-T	POLD1	c.1216C>T	p.L406F	Missense	10/27	-
12-133244129-G-A	POLE	c.2279C>T	p.A760V	Missense	20/49	-
12-133210804-G-A	POLE	c.5972C>T	p.S1991F	Missense	43/49	-
12-133256548-G-C	POLE	c.415C>G	p.L139V	Missense	5/49	-
12-133212495-G-A	POLE	c.5794C>T	p.R1932C	Missense	42/49	-
12-133245308-C-T	POLE	c.1939G>A	p.D647N	Missense	18/49	-
12-133257804-C-T	POLE	c.124G>A	p.D42N	Missense	2/49	-
3-138383975-T-C	PIK3CB	c.2575A>G	p.T859A	Missense	20/24	-
12-133253217-T-C	POLE	c.824A>G	p.D275G	Missense	9/49	-
15-99478082-C-T	IGF1R	c.2986C>T	p.R996W	Missense	16/21	-
12-133208980-G-A	POLE	c.6251C>T	p.S2084L	Missense	45/49	-
12-133236047-G-A	POLE	c.3109C>T	p.R1037C	Missense	26/49	-
17-7573984-A-C	TP53	c.1043T>G	p.L348W	Missense	10/11	-
12-133245277-T-C	POLE	c.1970A>G	p.N657S	Missense	18/49	-
12-133249340-T-C	POLE	c.1559A>G	p.Q520R	Missense	15/49	-
17-41256276-C-T	BRCA1	c.304G>A	p.A102T	Missense	6/23	-
12-133226031-C-T	POLE	c.3866G>A	p.R1289H	Missense	31/49	-
12-133253975-G-A	POLE	c.775C>T	p.R259C	Missense	8/49	-
12-133219287-G-A	POLE	c.4757C>T	p.A1586V	Missense	37/49	-
12-133219201-C-T	POLE	c.4843G>A	p.D1615N	Missense	37/49	-
17-37881982-G-T	ERBB2	c.2748G>T	p.M916I	Missense	23/27	-
17-37879673-G-A	ERBB2	c.2048G>A	p.R683Q	Missense	17/27	-
17-37871723-C-T	ERBB2	c.1247C>T	p.P416L	Missense	11/27	-
17-37871997-G-A	ERBB2	c.1318G>A	p.A440T	Missense	12/27	-
5-67593261-T-G	PIK3R1	c.2007T>G	p.H669Q	Missense	16/16	-
12-133225519-C-T	POLE	c.4145G>A	p.R1382H	Missense	32/49	-
12-56481859-C-T	ERBB3	c.787C>T	p.L263F	Missense	7/28	-
12-133257270-C-T	POLE	c.208G>A	p.E70K	Missense	3/49	-
12-133214631-C-T	POLE	c.5647G>A	p.A1883T	Missense	41/49	-
12-133249257-C-T	POLE	c.1642G>A	p.E548K	Missense	15/49	-
5-67588966-G-A	PIK3R1	c.1057G>A	p.G353R	Missense	9/16	-
5-67588966-G-C	PIK3R1	c.1057G>C	p.G353R	Missense	9/16	-
19-50905321-C-T	POLD1	c.529C>T	p.R177C	Missense	5/27	-
12-133235881-C-T	POLE	c.3275G>A	p.R1092K	Missense	26/49	-
17-7573991-C-G	TP53	c.1036G>C	p.E346Q	Missense	10/11	-
3-12650329-G-A	RAF1	c.517C>T	p.H173Y	Missense	5/17	-
12-133245479-G-A	POLE	c.1841C>T	p.P614L	Missense	17/49	-
12-133218369-T-G	POLE	c.5242A>C	p.M1748L	Missense	39/49	-
12-133253178-G-A	POLE	c.863C>T	p.A288V	Missense	9/49	-
12-133218369-T-A	POLE	c.5242A>T	p.M1748L	Missense	39/49	-
1-115252235-C-G	NRAS	c.405G>C	p.K135N	Missense	4/7	-
19-50918991-C-T	POLD1	c.2728C>T	p.R910W	Missense	22/27	-
1-115252235-C-A	NRAS	c.405G>T	p.K135N	Missense	4/7	-
19-50919042-A-C	POLD1	c.2779A>C	p.I927L	Missense	22/27	-
12-133201577-A-T	POLE	c.6661T>A	p.C2221S	Missense	48/49	-
12-133201576-C-G	POLE	c.6662G>C	p.C2221S	Missense	48/49	-
12-133252733-T-C	POLE	c.967A>G	p.T323A	Missense	10/49	-
1-9783347-C-T	PIK3CD	c.2591C>T	p.P864L	Missense	20/24	-
12-133248811-T-C	POLE	c.1784A>G	p.N595S	Missense	16/49	-
19-50905879-G-A	POLD1	c.851G>A	p.C284Y	Missense	8/27	-
19-50902143-G-T	POLD1	c.35G>T	p.G12V	Missense	2/27	-
3-12627203-G-A	RAF1	c.1513C>T	p.P505S	Missense	14/17	-
17-7579490-A-G	TP53	c.197T>C	p.M66T	Missense	4/11	-
10-123279557-T-A	FGFR2	c.875A>T	p.K292M	Missense	7/18	-
12-133256101-T-C	POLE	c.560A>G	p.Y187C	Missense	6/49	-
19-50918150-C-G	POLD1	c.2467C>G	p.R823G	Missense	20/27	-
12-133218864-C-A	POLE	c.5072G>T	p.R1691L	Missense	38/49	-
12-133212526-G-C	POLE	c.5763C>G	p.N1921K	Missense	42/49	-
12-133212526-G-T	POLE	c.5763C>A	p.N1921K	Missense	42/49	-
19-50919764-C-T	POLD1	c.2932C>T	p.R978C	Missense	23/27	-
12-133202852-C-T	POLE	c.6382G>A	p.D2128N	Missense	46/49	-
12-133220427-G-C	POLE	c.4286C>G	p.T1429S	Missense	33/49	-
12-133220428-T-A	POLE	c.4285A>T	p.T1429S	Missense	33/49	-
19-50910591-A-T	POLD1	c.1694A>T	p.H565L	Missense	14/27	-
19-50912792-G-T	POLD1	c.2023G>T	p.A675S	Missense	17/27	-
19-50918807-G-A	POLD1	c.2677G>A	p.D893N	Missense	21/27	-
12-133244151-A-G	POLE	c.2257T>C	p.F753L	Missense	20/49	-
12-133244149-G-T	POLE	c.2259C>A	p.F753L	Missense	20/49	-
12-133244149-G-C	POLE	c.2259C>G	p.F753L	Missense	20/49	-
19-50918111-G-T	POLD1	c.2428G>T	p.A810S	Missense	20/27	-
12-133201520-C-G	POLE	c.6718G>C	p.G2240R	Missense	48/49	-
12-133257795-C-T	POLE	c.133G>A	p.D45N	Missense	2/49	-
12-133249230-G-A	POLE	c.1669C>T	p.P557S	Missense	15/49	-
12-133245028-G-C	POLE	c.2087C>G	p.P696R	Missense	19/49	-
12-133241948-G-A	POLE	c.2408C>T	p.S803L	Missense	21/49	-
12-133234506-A-T	POLE	c.3326T>A	p.F1109Y	Missense	27/49	-
12-133225618-G-A	POLE	c.4046C>T	p.A1349V	Missense	32/49	-
7-128846362-C-T	SMO	c.1198C>T	p.R400C	Missense	6/12	-
19-50905779-G-T	POLD1	c.827G>T	p.R276M	Missense	7/27	-
12-133226088-A-C	POLE	c.3809T>G	p.V1270G	Missense	31/49	-
19-50912440-C-T	POLD1	c.1954C>T	p.R652W	Missense	16/27	-
19-50912389-G-A	POLD1	c.1903G>A	p.D635N	Missense	16/27	-
12-133220143-G-T	POLE	c.4294C>A	p.P1432T	Missense	34/49	-
12-133241991-C-T	POLE	c.2365G>A	p.A789T	Missense	21/49	-
12-133237682-T-C	POLE	c.2933A>G	p.E978G	Missense	25/49	-
19-50906446-G-T	POLD1	c.1107G>T	p.Q369H	Missense	9/27	-
19-50906446-G-C	POLD1	c.1107G>C	p.Q369H	Missense	9/27	-
19-50912882-G-T	POLD1	c.2113G>T	p.G705C	Missense	17/27	-
17-41258513-G-A	BRCA1	c.172C>T	p.P58S	Missense	4/23	-
7-55233084-G-A	EGFR	c.1834G>A	p.D612N	Missense	15/28	-
12-133218437-A-G	POLE	c.5174T>C	p.V1725A	Missense	39/49	-
19-50912479-A-T	POLD1	c.1993A>T	p.S665C	Missense	16/27	-
12-133210910-C-T	POLE	c.5866G>A	p.E1956K	Missense	43/49	-
19-50921175-T-C	POLD1	c.3295T>C	p.F1099L	Missense	27/27	-
19-50921177-C-A	POLD1	c.3297C>A	p.F1099L	Missense	27/27	-
12-133257815-C-T	POLE	c.113G>A	p.S38N	Missense	2/49	-
3-12647721-G-A	RAF1	c.659C>T	p.S220F	Missense	6/17	-
12-133252406-C-G	POLE	c.1021G>C	p.A341P	Missense	11/49	-
17-41256888-C-T	BRCA1	c.298G>A	p.E100K	Missense	5/23	-
12-133245525-C-T	POLE	c.1795G>A	p.V599M	Missense	17/49	-
19-50912435-C-T	POLD1	c.1949C>T	p.S650L	Missense	16/27	-
12-133219139-G-T	POLE	c.4905C>A	p.H1635Q	Missense	37/49	-
12-133219139-G-C	POLE	c.4905C>G	p.H1635Q	Missense	37/49	-
12-133219300-G-A	POLE	c.4744C>T	p.P1582S	Missense	37/49	-
3-12660186-C-T	RAF1	c.35G>A	p.S12N	Missense	2/17	-
12-133257854-G-A	POLE	c.74C>T	p.A25V	Missense	2/49	-
12-133225902-T-C	POLE	c.3995A>G	p.Q1332R	Missense	31/49	-
19-50919653-G-T	POLD1	c.2821G>T	p.D941Y	Missense	23/27	-
19-50905566-C-T	POLD1	c.694C>T	p.R232C	Missense	6/27	-
12-133219491-G-A	POLE	c.4643C>T	p.P1548L	Missense	36/49	-
12-133256084-T-C	POLE	c.577A>G	p.S193G	Missense	6/49	-
19-50902266-A-T	POLD1	c.158A>T	p.Q53L	Missense	2/27	-
12-133201368-C-T	POLE	c.6776G>A	p.R2259Q	Missense	49/49	-
17-7579349-A-T	TP53	c.338T>A	p.F113Y	Missense	4/11	-
12-133253230-C-T	POLE	c.811G>A	p.V271I	Missense	9/49	-
17-37881989-G-T	ERBB2	c.2755G>T	p.G919W	Missense	23/27	-
17-7573999-T-A	TP53	c.1028A>T	p.E343V	Missense	10/11	-
12-133254252-A-G	POLE	c.632T>C	p.I211T	Missense	7/49	-
19-50909526-C-T	POLD1	c.1330C>T	p.R444W	Missense	11/27	-
12-133234012-G-T	POLE	c.3382C>A	p.L1128M	Missense	28/49	-
12-133250213-G-A	POLE	c.1307C>T	p.P436L	Missense	13/49	-
12-133242015-C-A	POLE	c.2341G>T	p.A781S	Missense	21/49	-
12-133237646-A-C	POLE	c.2969T>G	p.F990C	Missense	25/49	-
12-133225935-C-T	POLE	c.3962G>A	p.R1321K	Missense	31/49	-
12-133244117-C-A	POLE	c.2291G>T	p.R764M	Missense	20/49	-
12-133238260-G-A	POLE	c.2717C>T	p.T906I	Missense	24/49	-
12-133215791-C-A	POLE	c.5472G>T	p.W1824C	Missense	40/49	-
12-133218308-T-C	POLE	c.5303A>G	p.D1768G	Missense	39/49	-
12-133212568-G-T	POLE	c.5721C>A	p.F1907L	Missense	42/49	-
12-133241981-T-C	POLE	c.2375A>G	p.K792R	Missense	21/49	-
12-133225525-G-A	POLE	c.4139C>T	p.S1380L	Missense	32/49	-
12-133249326-T-G	POLE	c.1573A>C	p.N525H	Missense	15/49	-
19-50912480-G-A	POLD1	c.1994G>A	p.S665N	Missense	16/27	-
19-50905504-G-C	POLD1	c.632G>C	p.R211P	Missense	6/27	-
19-50918708-G-A	POLD1	c.2578G>A	p.A860T	Missense	21/27	-
12-133249325-T-C	POLE	c.1574A>G	p.N525S	Missense	15/49	-
3-12650363-A-C	RAF1	c.483T>G	p.N161K	Missense	5/17	-
12-133249272-G-A	POLE	c.1627C>T	p.H543Y	Missense	15/49	-
19-50902667-G-A	POLD1	c.242G>A	p.R81Q	Missense	3/27	-
12-133219999-C-T	POLE	c.4438G>A	p.E1480K	Missense	34/49	-
12-133257762-G-A	POLE	c.166C>T	p.P56S	Missense	2/49	-
12-133263868-C-T	POLE	c.34G>A	p.D12N	Missense	1/49	-
12-133226465-G-A	POLE	c.3593C>T	p.A1198V	Missense	30/49	-
12-133240678-G-T	POLE	c.2618C>A	p.P873Q	Missense	23/49	-
12-133237601-G-A	POLE	c.3014C>T	p.S1005F	Missense	25/49	-
12-133242023-T-G	POLE	c.2333A>C	p.K778T	Missense	21/49	-
12-133238153-G-A	POLE	c.2824C>T	p.L942F	Missense	24/49	-
12-133218952-C-T	POLE	c.4984G>A	p.E1662K	Missense	38/49	-
12-133245077-G-A	POLE	c.2038C>T	p.R680C	Missense	19/49	-
12-133214706-G-A	POLE	c.5572C>T	p.R1858C	Missense	41/49	-
12-133219152-C-T	POLE	c.4892G>A	p.R1631H	Missense	37/49	-
12-133252691-C-T	POLE	c.1009G>A	p.E337K	Missense	10/49	-
2-29449875-C-T	ALK	c.2980G>A	p.E994K	Missense	18/29	-
12-133218276-G-A	POLE	c.5335C>T	p.P1779S	Missense	39/49	-
12-133236059-T-A	POLE	c.3097A>T	p.I1033F	Missense	26/49	-
12-133234003-C-T	POLE	c.3391G>A	p.D1131N	Missense	28/49	-
13-32890664-G-A	BRCA2	c.67G>A	p.D23N	Missense	2/27	-
17-41256890-A-G	BRCA1	c.296T>C	p.L99S	Missense	5/23	-
12-133219908-G-A	POLE	c.4453C>T	p.R1485C	Missense	35/49	-
X-47429292-G-A	ARAF	c.1420G>A	p.A474T	Missense	14/16	-
12-133225927-G-A	POLE	c.3970C>T	p.R1324C	Missense	31/49	-
12-133241916-A-C	POLE	c.2440T>G	p.S814A	Missense	21/49	-
12-133240978-G-A	POLE	c.2539C>T	p.R847W	Missense	22/49	-
12-133202755-C-A	POLE	c.6479G>T	p.S2160I	Missense	46/49	-
12-133214684-T-C	POLE	c.5594A>G	p.Y1865C	Missense	41/49	-
12-133253159-C-G	POLE	c.882G>C	p.M294I	Missense	9/49	-
12-133253159-C-T	POLE	c.882G>A	p.M294I	Missense	9/49	-
12-133244981-G-A	POLE	c.2134C>T	p.R712C	Missense	19/49	-
12-133241954-T-C	POLE	c.2402A>G	p.Y801C	Missense	21/49	-
12-133252682-C-T	POLE	c.1018G>A	p.E340K	Missense	10/49	-
19-50919768-C-T	POLD1	c.2936C>T	p.A979V	Missense	23/27	-
12-133209252-G-A	POLE	c.6134C>T	p.P2045L	Missense	44/49	-
12-133252086-C-A	POLE	c.1124G>T	p.R375L	Missense	12/49	-
12-133212572-G-T	POLE	c.5717C>A	p.S1906Y	Missense	42/49	-
12-133214670-G-A	POLE	c.5608C>T	p.R1870C	Missense	41/49	-
12-133254217-C-T	POLE	c.667G>A	p.E223K	Missense	7/49	-
12-133257197-A-C	POLE	c.281T>G	p.F94C	Missense	3/49	-
12-133209300-C-A	POLE	c.6086G>T	p.G2029V	Missense	44/49	-
19-50905080-C-T	POLD1	c.362C>T	p.S121F	Missense	4/27	-
19-50919924-C-T	POLD1	c.3011C>T	p.A1004V	Missense	24/27	-
12-133233839-C-G	POLE	c.3465G>C	p.K1155N	Missense	29/49	-
12-133237628-C-T	POLE	c.2987G>A	p.G996D	Missense	25/49	-
17-37868193-C-T	ERBB2	c.914C>T	p.S305F	Missense	8/27	-
19-50918125-C-G	POLD1	c.2442C>G	p.F814L	Missense	20/27	-
17-7577135-T-G	TP53	c.803A>C	p.N268T	Missense	8/11	-
12-133234008-T-C	POLE	c.3386A>G	p.D1129G	Missense	28/49	-
12-133219097-C-G	POLE	c.4947G>C	p.M1649I	Missense	37/49	-
12-133219097-C-T	POLE	c.4947G>A	p.M1649I	Missense	37/49	-
12-133219097-C-A	POLE	c.4947G>T	p.M1649I	Missense	37/49	-
12-133218258-T-C	POLE	c.5353A>G	p.T1785A	Missense	39/49	-
12-133233839-C-A	POLE	c.3465G>T	p.K1155N	Missense	29/49	-
19-50917133-G-C	POLD1	c.2385G>C	p.E795D	Missense	19/27	-
19-50917133-G-T	POLD1	c.2385G>T	p.E795D	Missense	19/27	-
19-50910418-A-G	POLD1	c.1673A>G	p.Q558R	Missense	13/27	-
19-50905630-G-A	POLD1	c.758G>A	p.R253Q	Missense	6/27	-
12-133249227-A-T	POLE	c.1672T>A	p.C558S	Missense	15/49	-
12-133249226-C-G	POLE	c.1673G>C	p.C558S	Missense	15/49	-
12-133218434-C-T	POLE	c.5177G>A	p.C1726Y	Missense	39/49	-
19-50909541-G-A	POLD1	c.1345G>A	p.V449I	Missense	11/27	-
19-50912143-C-T	POLD1	c.1877C>T	p.T626I	Missense	15/27	-
12-133236076-G-C	POLE	c.3080C>G	p.S1027C	Missense	26/49	-
12-133237724-G-A	POLE	c.2891C>T	p.S964F	Missense	25/49	-
12-133225552-C-A	POLE	c.4112G>T	p.R1371L	Missense	32/49	-
3-12653512-A-C	RAF1	c.257T>G	p.L86R	Missense	3/17	-
12-133249223-C-T	POLE	c.1676G>A	p.R559Q	Missense	15/49	-
1-9784908-G-C	PIK3CD	c.2911G>C	p.G971R	Missense	23/24	-
19-50912858-G-A	POLD1	c.2089G>A	p.A697T	Missense	17/27	-
12-133209353-C-T	POLE	c.6033G>A	p.M2011I	Missense	44/49	-
19-50912914-G-C	POLD1	c.2145G>C	p.E715D	Missense	17/27	-
19-50912914-G-T	POLD1	c.2145G>T	p.E715D	Missense	17/27	-
19-50905558-A-G	POLD1	c.686A>G	p.Q229R	Missense	6/27	-
12-133212608-A-G	POLE	c.5681T>C	p.I1894T	Missense	42/49	-
17-7573993-T-G	TP53	c.1034A>C	p.N345T	Missense	10/11	-
12-133233957-G-A	POLE	c.3437C>T	p.T1146I	Missense	28/49	-
12-133240990-T-C	POLE	c.2527A>G	p.I843V	Missense	22/49	-
12-133252072-C-T	POLE	c.1138G>A	p.G380S	Missense	12/49	-
12-133257212-T-G	POLE	c.266A>C	p.D89A	Missense	3/49	-
7-140439698-C-T	BRAF	c.2041G>A	p.V681I	Missense	17/18	-
12-133226089-C-A	POLE	c.3808G>T	p.V1270F	Missense	31/49	-
19-50912486-G-T	POLD1	c.2000G>T	p.R667L	Missense	16/27	-
19-50905289-G-A	POLD1	c.497G>A	p.R166Q	Missense	5/27	-
17-37872145-C-A	ERBB2	c.1466C>A	p.P489Q	Missense	12/27	-
17-37881977-C-A	ERBB2	c.2743C>A	p.L915M	Missense	23/27	-
19-50918840-G-T	POLD1	c.2710G>T	p.A904S	Missense	21/27	-
17-37883255-G-T	ERBB2	c.3158G>T	p.R1053M	Missense	25/27	-
7-140481399-G-T	BRAF	c.1409C>A	p.T470K	Missense	11/18	-
19-50918198-C-T	POLD1	c.2515C>T	p.L839F	Missense	20/27	-
17-41256923-T-A	BRCA1	c.263A>T	p.K88I	Missense	5/23	-
19-50905170-C-T	POLD1	c.452C>T	p.P151L	Missense	4/27	-
19-50917048-C-T	POLD1	c.2300C>T	p.S767L	Missense	19/27	-
19-50921172-C-T	POLD1	c.3292C>T	p.R1098C	Missense	27/27	-
19-50905630-G-T	POLD1	c.758G>T	p.R253L	Missense	6/27	-
17-7573990-T-A	TP53	c.1037A>T	p.E346V	Missense	10/11	-
19-50905733-G-T	POLD1	c.781G>T	p.V261F	Missense	7/27	-
19-50919900-C-T	POLD1	c.2987C>T	p.T996M	Missense	24/27	-
19-50905342-G-A	POLD1	c.550G>A	p.G184R	Missense	5/27	-
19-50905342-G-C	POLD1	c.550G>C	p.G184R	Missense	5/27	-
19-50918127-C-T	POLD1	c.2444C>T	p.S815F	Missense	20/27	-
19-50910273-G-A	POLD1	c.1528G>A	p.V510M	Missense	13/27	-
19-50912817-G-A	POLD1	c.2048G>A	p.R683H	Missense	17/27	-
19-50919000-G-A	POLD1	c.2737G>A	p.G913R	Missense	22/27	-
19-50919000-G-C	POLD1	c.2737G>C	p.G913R	Missense	22/27	-
19-50905313-G-T	POLD1	c.521G>T	p.R174L	Missense	5/27	-
19-50918843-G-A	POLD1	c.2713G>A	p.E905K	Missense	21/27	-
19-50912432-C-T	POLD1	c.1946C>T	p.T649I	Missense	16/27	-
19-50917131-G-A	POLD1	c.2383G>A	p.E795K	Missense	19/27	-
19-50912852-G-A	POLD1	c.2083G>A	p.V695M	Missense	17/27	-
19-50916768-C-T	POLD1	c.2240C>T	p.T747I	Missense	18/27	-
19-50920326-C-T	POLD1	c.3092C>T	p.P1031L	Missense	25/27	-
19-50918826-C-T	POLD1	c.2696C>T	p.A899V	Missense	21/27	-
19-50912903-C-T	POLD1	c.2134C>T	p.P712S	Missense	17/27	-
19-50919875-C-T	POLD1	c.2962C>T	p.H988Y	Missense	24/27	-
19-50912805-A-G	POLD1	c.2036A>G	p.D679G	Missense	17/27	-
19-50919657-C-T	POLD1	c.2825C>T	p.P942L	Missense	23/27	-
19-50902166-G-A	POLD1	c.58G>A	p.G20R	Missense	2/27	-
19-50902166-G-C	POLD1	c.58G>C	p.G20R	Missense	2/27	-
19-50912073-T-C	POLD1	c.1807T>C	p.F603L	Missense	15/27	-
19-50912075-C-A	POLD1	c.1809C>A	p.F603L	Missense	15/27	-
19-50912075-C-G	POLD1	c.1809C>G	p.F603L	Missense	15/27	-
19-50905717-G-C	POLD1	c.765G>C	p.M255I	Missense	7/27	-
19-50905717-G-A	POLD1	c.765G>A	p.M255I	Missense	7/27	-
19-50905717-G-T	POLD1	c.765G>T	p.M255I	Missense	7/27	-
12-133218272-G-C	POLE	c.5339C>G	p.A1780G	Missense	39/49	-
19-50905740-G-A	POLD1	c.788G>A	p.C263Y	Missense	7/27	-
19-50905927-C-T	POLD1	c.899C>T	p.P300L	Missense	8/27	-
19-50916773-G-A	POLD1	c.2245G>A	p.A749T	Missense	18/27	-
19-50905077-G-T	POLD1	c.359G>T	p.G120V	Missense	4/27	-
19-50902190-G-A	POLD1	c.82G>A	p.A28T	Missense	2/27	-
19-50912104-C-T	POLD1	c.1838C>T	p.A613V	Missense	15/27	-
19-50919755-G-T	POLD1	c.2923G>T	p.G975C	Missense	23/27	-
12-133248888-G-T	POLE	c.1707C>A	p.F569L	Missense	16/49	-
12-133248888-G-C	POLE	c.1707C>G	p.F569L	Missense	16/49	-
12-133248890-A-G	POLE	c.1705T>C	p.F569L	Missense	16/49	-
12-133201343-C-G	POLE	c.6801G>C	p.M2267I	Missense	49/49	-
12-133201343-C-T	POLE	c.6801G>A	p.M2267I	Missense	49/49	-
19-50905926-C-A	POLD1	c.898C>A	p.P300T	Missense	8/27	-
12-133201343-C-A	POLE	c.6801G>T	p.M2267I	Missense	49/49	-
19-50902636-C-T	POLD1	c.211C>T	p.P71S	Missense	3/27	-
12-133218429-C-G	POLE	c.5182G>C	p.E1728Q	Missense	39/49	-
19-50905944-C-T	POLD1	c.916C>T	p.R306C	Missense	8/27	-
12-133219148-C-T	POLE	c.4896G>A	p.M1632I	Missense	37/49	-
19-50912134-G-T	POLD1	c.1868G>T	p.R623L	Missense	15/27	-
12-133254219-C-T	POLE	c.665G>A	p.R222H	Missense	7/49	-
19-50912894-G-T	POLD1	c.2125G>T	p.G709C	Missense	17/27	-
7-140501267-G-A	BRAF	c.805C>T	p.H269Y	Missense	6/18	-
12-133226024-C-A	POLE	c.3873G>T	p.K1291N	Missense	31/49	-
19-50918097-G-T	POLD1	c.2414G>T	p.S805I	Missense	20/27	-
12-133202741-G-A	POLE	c.6493C>T	p.R2165C	Missense	46/49	-
12-133225974-C-A	POLE	c.3923G>T	p.R1308L	Missense	31/49	-
12-133257827-C-T	POLE	c.101G>A	p.R34H	Missense	2/49	-
19-50905733-G-A	POLD1	c.781G>A	p.V261I	Missense	7/27	-
7-116340199-C-A	MET	c.1061C>A	p.A354D	Missense	2/21	-
12-133219153-G-A	POLE	c.4891C>T	p.R1631C	Missense	37/49	-
19-50912844-C-T	POLD1	c.2075C>T	p.A692V	Missense	17/27	-
19-50902310-G-A	POLD1	c.202G>A	p.G68R	Missense	2/27	-
19-50902310-G-C	POLD1	c.202G>C	p.G68R	Missense	2/27	-
12-133244968-G-A	POLE	c.2147C>T	p.A716V	Missense	19/49	-
19-50909766-G-A	POLD1	c.1486G>A	p.D496N	Missense	12/27	-
12-133209045-G-T	POLE	c.6186C>A	p.S2062R	Missense	45/49	-
8-38287289-T-A	FGFR1	c.269A>T	p.D90V	Missense	3/18	-
12-133215865-C-T	POLE	c.5398G>A	p.V1800M	Missense	40/49	-
12-133252032-C-T	POLE	c.1178G>A	p.S393N	Missense	12/49	-
12-133202802-G-T	POLE	c.6432C>A	p.F2144L	Missense	46/49	-
19-50906421-C-T	POLD1	c.1082C>T	p.A361V	Missense	9/27	-
17-41243855-A-C	BRCA1	c.3693T>G	p.F1231L	Missense	10/23	-
17-41243855-A-T	BRCA1	c.3693T>A	p.F1231L	Missense	10/23	-
12-133263852-C-T	POLE	c.50G>A	p.G17D	Missense	1/49	-
12-133248851-G-A	POLE	c.1744C>T	p.L582F	Missense	16/49	-
12-133235926-C-T	POLE	c.3230G>A	p.R1077H	Missense	26/49	-
13-32953592-G-T	BRCA2	c.8893G>T	p.D2965Y	Missense	22/27	-
12-133225989-C-A	POLE	c.3908G>T	p.R1303M	Missense	31/49	-
17-41276038-T-A	BRCA1	c.76A>T	p.I26F	Missense	2/23	-
17-41256272-T-A	BRCA1	c.308A>T	p.N103I	Missense	6/23	-
17-41256272-T-G	BRCA1	c.308A>C	p.N103T	Missense	6/23	-
17-41256275-G-A	BRCA1	c.305C>T	p.A102V	Missense	6/23	-
17-41256275-G-T	BRCA1	c.305C>A	p.A102E	Missense	6/23	-
17-41256276-C-A	BRCA1	c.304G>T	p.A102S	Missense	6/23	-
17-41256887-T-A	BRCA1	c.299A>T	p.E100V	Missense	5/23	-
17-41256887-T-C	BRCA1	c.299A>G	p.E100G	Missense	5/23	-
17-41256887-T-G	BRCA1	c.299A>C	p.E100A	Missense	5/23	-
17-41256888-C-G	BRCA1	c.298G>C	p.E100Q	Missense	5/23	-
17-41256890-A-C	BRCA1	c.296T>G	p.L99W	Missense	5/23	-
17-41256951-A-T	BRCA1	c.235T>A	p.F79I	Missense	5/23	-
17-41256962-T-A	BRCA1	c.224A>T	p.E75V	Missense	5/23	-
12-133244225-C-T	POLE	c.2183G>A	p.R728Q	Missense	20/49	-
12-133210901-T-C	POLE	c.5875A>G	p.R1959G	Missense	43/49	-
19-50909461-G-A	POLD1	c.1265G>A	p.G422D	Missense	11/27	-
19-50905343-G-A	POLD1	c.551G>A	p.G184E	Missense	5/27	-
17-7579452-C-A	TP53	c.235G>T	p.A79S	Missense	4/11	-
19-50906776-G-C	POLD1	c.1164G>C	p.M388I	Missense	10/27	-
19-50906776-G-A	POLD1	c.1164G>A	p.M388I	Missense	10/27	-
19-50906776-G-T	POLD1	c.1164G>T	p.M388I	Missense	10/27	-
19-50912387-A-C	POLD1	c.1901A>C	p.E634A	Missense	16/27	-
12-133235960-C-T	POLE	c.3196G>A	p.D1066N	Missense	26/49	-
12-133257782-C-T	POLE	c.146G>A	p.G49D	Missense	2/49	-
1-9782090-A-G	PIK3CD	c.2113A>G	p.K705E	Missense	17/24	-
12-133241903-T-C	POLE	c.2453A>G	p.Y818C	Missense	21/49	-
12-133252386-C-G	POLE	c.1041G>C	p.W347C	Missense	11/49	-
12-133226381-G-A	POLE	c.3677C>T	p.P1226L	Missense	30/49	-
12-133245026-G-T	POLE	c.2089C>A	p.P697T	Missense	19/49	-
12-133219885-G-C	POLE	c.4476C>G	p.H1492Q	Missense	35/49	-
12-133219290-A-T	POLE	c.4754T>A	p.I1585N	Missense	37/49	-
12-133201564-C-T	POLE	c.6674G>A	p.R2225H	Missense	48/49	-
12-133201316-C-A	POLE	c.6828G>T	p.W2276C	Missense	49/49	-
12-133256146-G-A	POLE	c.515C>T	p.P172L	Missense	6/49	-
12-133252376-C-T	POLE	c.1051G>A	p.V351I	Missense	11/49	-
19-50905545-C-T	POLD1	c.673C>T	p.R225C	Missense	6/27	-
7-116397558-C-T	MET	c.1930C>T	p.H644Y	Missense	7/21	-
19-50912808-C-T	POLD1	c.2039C>T	p.P680L	Missense	17/27	-
12-133219567-T-C	POLE	c.4567A>G	p.M1523V	Missense	36/49	-
19-50921136-C-T	POLD1	c.3256C>T	p.R1086W	Missense	27/27	-
12-133249850-T-C	POLE	c.1373A>G	p.Y458C	Missense	14/49	-
12-133209305-C-A	POLE	c.6081G>T	p.R2027S	Missense	44/49	-
12-133212570-A-G	POLE	c.5719T>C	p.F1907L	Missense	42/49	-
12-133212568-G-C	POLE	c.5721C>G	p.F1907L	Missense	42/49	-
12-133248853-G-A	POLE	c.1742C>T	p.A581V	Missense	16/49	-
12-133241913-A-G	POLE	c.2443T>C	p.F815L	Missense	21/49	-
12-133241911-G-C	POLE	c.2445C>G	p.F815L	Missense	21/49	-
17-37881982-G-C	ERBB2	c.2748G>C	p.M916I	Missense	23/27	-
19-50912395-T-C	POLD1	c.1909T>C	p.F637L	Missense	16/27	-
19-50912397-C-G	POLD1	c.1911C>G	p.F637L	Missense	16/27	-
7-140501297-A-G	BRAF	c.775T>C	p.F259L	Missense	6/18	-
7-140501295-G-T	BRAF	c.777C>A	p.F259L	Missense	6/18	-
17-37882863-C-T	ERBB2	c.2921C>T	p.S974F	Missense	24/27	-
17-37881982-G-A	ERBB2	c.2748G>A	p.M916I	Missense	23/27	-
17-37882022-G-A	ERBB2	c.2788G>A	p.E930K	Missense	23/27	-
17-37881324-T-G	ERBB2	c.2516T>G	p.V839G	Missense	21/27	-
17-37883578-G-C	ERBB2	c.3190G>C	p.E1064Q	Missense	26/27	-
17-37881078-T-A	ERBB2	c.2407T>A	p.Y803N	Missense	20/27	-
17-37881132-G-A	ERBB2	c.2461G>A	p.D821N	Missense	20/27	-
17-37880180-G-C	ERBB2	c.2224G>C	p.D742H	Missense	19/27	-
12-25362841-A-G	KRAS	c.455T>C	p.V152A	Missense	5/5	-
12-25380280-C-A	KRAS	c.178G>T	p.G60C	Missense	3/5	-
17-7573998-C-G	TP53	c.1029G>C	p.E343D	Missense	10/11	-
17-7573978-A-C	TP53	c.1049T>G	p.L350R	Missense	10/11	-
17-7574008-A-C	TP53	c.1019T>G	p.M340R	Missense	10/11	-
17-7576923-A-T	TP53	c.923T>A	p.L308Q	Missense	9/11	-
17-7573003-A-G	TP53	c.1106T>C	p.L369P	Missense	11/11	-
17-7579467-C-G	TP53	c.220G>C	p.A74P	Missense	4/11	-
17-7573998-C-A	TP53	c.1029G>T	p.E343D	Missense	10/11	-
3-138376574-A-G	PIK3CB	c.2900T>C	p.V967A	Missense	22/24	-
17-7578416-C-G	TP53	c.514G>C	p.V172L	Missense	5/11	-
17-7576920-G-T	TP53	c.926C>A	p.P309H	Missense	9/11	-
17-7579391-G-T	TP53	c.296C>A	p.S99Y	Missense	4/11	-
17-7573972-T-C	TP53	c.1055A>G	p.D352G	Missense	10/11	-
17-7573972-T-A	TP53	c.1055A>T	p.D352V	Missense	10/11	-
17-7573972-T-G	TP53	c.1055A>C	p.D352A	Missense	10/11	-
17-7573994-T-G	TP53	c.1033A>C	p.N345H	Missense	10/11	-
17-7573994-T-A	TP53	c.1033A>T	p.N345Y	Missense	10/11	-
3-138409870-T-G	PIK3CB	c.2008A>C	p.I670L	Missense	15/24	-
3-138461549-C-T	PIK3CB	c.472G>A	p.E158K	Missense	5/24	-
19-50912125-C-T	POLD1	c.1859C>T	p.T620M	Missense	15/27	-
12-133252055-C-A	POLE	c.1155G>T	p.Q385H	Missense	12/49	-
19-50918155-G-T	POLD1	c.2472G>T	p.M824I	Missense	20/27	-
19-50918112-C-A	POLD1	c.2429C>A	p.A810E	Missense	20/27	-
3-138431123-A-C	PIK3CB	c.1326T>G	p.N442K	Missense	10/24	-
3-138417775-A-T	PIK3CB	c.1744T>A	p.W582R	Missense	13/24	-
3-138461473-G-A	PIK3CB	c.548C>T	p.S183F	Missense	5/24	-
3-138456596-C-A	PIK3CB	c.754G>T	p.G252W	Missense	6/24	-
3-138474789-C-G	PIK3CB	c.204G>C	p.M68I	Missense	4/24	-
12-133240962-T-C	POLE	c.2555A>G	p.Q852R	Missense	22/49	-
19-50905870-C-T	POLD1	c.842C>T	p.A281V	Missense	8/27	-
3-12660046-G-T	RAF1	c.175C>A	p.R59S	Missense	2/17	-
3-12647712-C-A	RAF1	c.668G>T	p.R223M	Missense	6/17	-
12-133245290-C-A	POLE	c.1957G>T	p.A653S	Missense	18/49	-
X-47428974-G-A	ARAF	c.1337G>A	p.G446D	Missense	13/16	-
19-50910621-C-T	POLD1	c.1724C>T	p.S575L	Missense	14/27	-
12-56477570-G-A	ERBB3	c.118G>A	p.G40S	Missense	2/28	-
17-37866379-G-C	ERBB2	c.684G>C	p.K228N	Missense	6/27	-
19-41745210-T-A	AXL	c.1276T>A	p.W426R	Missense	9/20	-
12-133201525-C-T	POLE	c.6713G>A	p.C2238Y	Missense	48/49	-
12-133245441-C-T	POLE	c.1879G>A	p.V627M	Missense	17/49	-
19-50918136-C-T	POLD1	c.2453C>T	p.P818L	Missense	20/27	-
19-50905095-G-A	POLD1	c.377G>A	p.R126H	Missense	4/27	-
12-133209298-C-A	POLE	c.6088G>T	p.A2030S	Missense	44/49	-
12-133252087-G-A	POLE	c.1123C>T	p.R375W	Missense	12/49	-
X-47429358-G-T	ARAF	c.1486G>T	p.G496W	Missense	14/16	-
19-50905915-T-G	POLD1	c.887T>G	p.V296G	Missense	8/27	-
12-133253220-A-G	POLE	c.821T>C	p.F274S	Missense	9/49	-
19-50918736-C-T	POLD1	c.2606C>T	p.S869L	Missense	21/27	-
19-50918831-G-A	POLD1	c.2701G>A	p.V901M	Missense	21/27	-
19-50916702-G-A	POLD1	c.2174G>A	p.R725H	Missense	18/27	-
19-50905951-C-T	POLD1	c.923C>T	p.A308V	Missense	8/27	-
19-50919872-G-A	POLD1	c.2959G>A	p.D987N	Missense	24/27	-
17-37866379-G-T	ERBB2	c.684G>T	p.K228N	Missense	6/27	-
12-133244990-C-T	POLE	c.2125G>A	p.E709K	Missense	19/49	-
12-133237688-C-T	POLE	c.2927G>A	p.R976H	Missense	25/49	-
12-133218407-G-A	POLE	c.5204C>T	p.A1735V	Missense	39/49	-
12-133257742-C-A	POLE	c.186G>T	p.W62C	Missense	2/49	-
12-133219125-T-C	POLE	c.4919A>G	p.D1640G	Missense	37/49	-
19-50905525-G-T	POLD1	c.653G>T	p.R218L	Missense	6/27	-
12-133236065-C-T	POLE	c.3091G>A	p.E1031K	Missense	26/49	-
7-140534602-C-T	BRAF	c.311G>A	p.G104E	Missense	3/18	-
12-133263856-C-T	POLE	c.46G>A	p.D16N	Missense	1/49	-
12-133212519-C-T	POLE	c.5770G>A	p.G1924R	Missense	42/49	-
12-133212519-C-G	POLE	c.5770G>C	p.G1924R	Missense	42/49	-
19-50910246-A-C	POLD1	c.1501A>C	p.N501H	Missense	13/27	-
12-133245521-C-T	POLE	c.1799G>A	p.C600Y	Missense	17/49	-
19-50917056-G-A	POLD1	c.2308G>A	p.E770K	Missense	19/27	-
19-50905900-T-C	POLD1	c.872T>C	p.L291P	Missense	8/27	-
19-50918133-G-A	POLD1	c.2450G>A	p.R817Q	Missense	20/27	-
12-133209367-C-T	POLE	c.6019G>A	p.V2007M	Missense	44/49	-
12-133245007-G-A	POLE	c.2108C>T	p.P703L	Missense	19/49	-
19-50906795-G-A	POLD1	c.1183G>A	p.G395S	Missense	10/27	-
12-133257788-C-T	POLE	c.140G>A	p.R47Q	Missense	2/49	-
19-50902154-A-G	POLD1	c.46A>G	p.K16E	Missense	2/27	-
19-50912437-G-T	POLD1	c.1951G>T	p.V651L	Missense	16/27	-
19-50918095-C-G	POLD1	c.2412C>G	p.I804M	Missense	20/27	-
12-133240633-A-G	POLE	c.2663T>C	p.V888A	Missense	23/49	-
19-50919942-A-C	POLD1	c.3029A>C	p.N1010T	Missense	24/27	-
12-133226355-G-A	POLE	c.3703C>T	p.L1235F	Missense	30/49	-
19-50912470-A-G	POLD1	c.1984A>G	p.N662D	Missense	16/27	-
19-50905056-G-T	POLD1	c.338G>T	p.G113V	Missense	4/27	-
12-133236066-G-T	POLE	c.3090C>A	p.F1030L	Missense	26/49	-
19-50906367-G-A	POLD1	c.1028G>A	p.R343H	Missense	9/27	-
12-133252774-T-C	POLE	c.926A>G	p.N309S	Missense	10/49	-
12-133256167-T-C	POLE	c.494A>G	p.K165R	Missense	6/49	-
19-50909745-G-T	POLD1	c.1465G>T	p.V489L	Missense	12/27	-
19-50912865-C-T	POLD1	c.2096C>T	p.S699F	Missense	17/27	-
8-38277227-T-C	FGFR1	c.1108A>G	p.T370A	Missense	9/18	-
3-12660160-C-T	RAF1	c.61G>A	p.V21M	Missense	2/17	-
12-133252336-C-A	POLE	c.1091G>T	p.G364V	Missense	11/49	-
12-133249775-G-A	POLE	c.1448C>T	p.T483I	Missense	14/49	-
17-37872773-C-T	ERBB2	c.1652C>T	p.P551L	Missense	14/27	-
19-50906327-G-A	POLD1	c.988G>A	p.E330K	Missense	9/27	-
12-133240639-G-A	POLE	c.2657C>T	p.P886L	Missense	23/49	-
19-50905175-C-T	POLD1	c.457C>T	p.P153S	Missense	4/27	-
2-29455230-G-A	ALK	c.2572C>T	p.P858S	Missense	15/29	-
19-50905492-C-T	POLD1	c.620C>T	p.S207F	Missense	6/27	-
12-133225550-C-T	POLE	c.4114G>A	p.V1372I	Missense	32/49	-
12-133208914-T-C	POLE	c.6317A>G	p.K2106R	Missense	45/49	-
19-50905267-G-A	POLD1	c.475G>A	p.E159K	Missense	5/27	-
12-133219313-C-G	POLE	c.4731G>C	p.E1577D	Missense	37/49	-
12-133244945-C-T	POLE	c.2170G>A	p.A724T	Missense	19/49	-
7-140476718-C-T	BRAF	c.1688G>A	p.G563D	Missense	13/18	-
19-50910629-G-A	POLD1	c.1732G>A	p.G578S	Missense	14/27	-
19-50905488-C-T	POLD1	c.616C>T	p.P206S	Missense	6/27	-
19-50902301-G-C	POLD1	c.193G>C	p.V65L	Missense	2/27	-
19-50905076-G-C	POLD1	c.358G>C	p.G120R	Missense	4/27	-
19-50909487-A-G	POLD1	c.1291A>G	p.I431V	Missense	11/27	-
19-50909562-C-G	POLD1	c.1366C>G	p.Q456E	Missense	11/27	-
19-50905763-G-A	POLD1	c.811G>A	p.G271R	Missense	7/27	-
19-50905763-G-C	POLD1	c.811G>C	p.G271R	Missense	7/27	-
19-50912416-G-A	POLD1	c.1930G>A	p.D644N	Missense	16/27	-
19-50919886-C-G	POLD1	c.2973C>G	p.C991W	Missense	24/27	-
19-50919975-A-C	POLD1	c.3062A>C	p.H1021P	Missense	24/27	-
19-50920337-G-C	POLD1	c.3103G>C	p.E1035Q	Missense	25/27	-
12-133209373-C-T	POLE	c.6013G>A	p.V2005M	Missense	44/49	-
9-98229655-G-A	PTCH1	c.2303C>T	p.T768I	Missense	15/24	-
12-133219871-T-C	POLE	c.4490A>G	p.K1497R	Missense	35/49	-
12-133254184-T-C	POLE	c.700A>G	p.I234V	Missense	7/49	-
12-133245067-T-C	POLE	c.2048A>G	p.Y683C	Missense	19/49	-
12-133245253-C-T	POLE	c.1994G>A	p.R665Q	Missense	18/49	-
12-133219814-T-C	POLE	c.4547A>G	p.D1516G	Missense	35/49	-
7-128850291-G-C	SMO	c.1554G>C	p.E518D	Missense	9/12	-
7-128850291-G-T	SMO	c.1554G>T	p.E518D	Missense	9/12	-
12-133219303-C-A	POLE	c.4741G>T	p.G1581W	Missense	37/49	-
19-50919867-G-A	POLD1	c.2954G>A	p.R985Q	Missense	24/27	-
19-50921101-G-A	POLD1	c.3221G>A	p.R1074Q	Missense	27/27	-
19-50919867-G-T	POLD1	c.2954G>T	p.R985L	Missense	24/27	-
12-133235980-C-A	POLE	c.3176G>T	p.R1059L	Missense	26/49	-
12-133244145-C-T	POLE	c.2263G>A	p.V755M	Missense	20/49	-
12-133225983-C-A	POLE	c.3914G>T	p.G1305V	Missense	31/49	-
19-50902158-G-T	POLD1	c.50G>T	p.R17L	Missense	2/27	-
12-133240659-C-G	POLE	c.2637G>C	p.K879N	Missense	23/49	-
19-50919879-C-T	POLD1	c.2966C>T	p.T989M	Missense	24/27	-
12-133238234-C-T	POLE	c.2743G>A	p.E915K	Missense	24/49	-
12-133245312-C-G	POLE	c.1935G>C	p.M645I	Missense	18/49	-
12-133245312-C-T	POLE	c.1935G>A	p.M645I	Missense	18/49	-
12-133245312-C-A	POLE	c.1935G>T	p.M645I	Missense	18/49	-
12-133209305-C-G	POLE	c.6081G>C	p.R2027S	Missense	44/49	-
19-50918155-G-A	POLD1	c.2472G>A	p.M824I	Missense	20/27	-
19-50918155-G-C	POLD1	c.2472G>C	p.M824I	Missense	20/27	-
19-50905479-G-A	POLD1	c.607G>A	p.G203R	Missense	6/27	-
12-133249269-C-T	POLE	c.1630G>A	p.V544M	Missense	15/49	-
19-50910611-G-A	POLD1	c.1714G>A	p.V572M	Missense	14/27	-
12-133245025-G-T	POLE	c.2090C>A	p.P697H	Missense	19/49	-
12-133252767-C-A	POLE	c.933G>T	p.E311D	Missense	10/49	-
12-133250249-A-T	POLE	c.1271T>A	p.L424H	Missense	13/49	-
12-133250262-C-A	POLE	c.1258G>T	p.G420C	Missense	13/49	-
12-133249830-C-A	POLE	c.1393G>T	p.A465S	Missense	14/49	-
19-50905873-C-T	POLD1	c.845C>T	p.T282M	Missense	8/27	-
12-133240612-G-A	POLE	c.2684C>T	p.A895V	Missense	23/49	-
12-133241043-C-T	POLE	c.2474G>A	p.R825H	Missense	22/49	-
12-133241934-G-A	POLE	c.2422C>T	p.H808Y	Missense	21/49	-
12-133249836-C-T	POLE	c.1387G>A	p.A463T	Missense	14/49	-
12-133242015-C-T	POLE	c.2341G>A	p.A781T	Missense	21/49	-
12-133218269-C-T	POLE	c.5342G>A	p.S1781N	Missense	39/49	-
12-133220128-C-T	POLE	c.4309G>A	p.A1437T	Missense	34/49	-
12-133226462-T-C	POLE	c.3596A>G	p.E1199G	Missense	30/49	-
19-50910427-G-T	POLD1	c.1682G>T	p.R561L	Missense	13/27	-
19-50909557-G-T	POLD1	c.1361G>T	p.R454L	Missense	11/27	-
12-133252065-C-T	POLE	c.1145G>A	p.S382N	Missense	12/49	-
19-50921118-T-C	POLD1	c.3238T>C	p.Y1080H	Missense	27/27	-
19-50917074-C-T	POLD1	c.2326C>T	p.R776W	Missense	19/27	-
12-133249851-A-G	POLE	c.1372T>C	p.Y458H	Missense	14/49	-
12-133220032-C-G	POLE	c.4405G>C	p.E1469Q	Missense	34/49	-
3-138409857-A-G	PIK3CB	c.2021T>C	p.L674P	Missense	15/24	-
19-50902142-G-T	POLD1	c.34G>T	p.G12W	Missense	2/27	-
7-140453081-C-G	BRAF	c.1854G>C	p.L618F	Missense	15/18	-
19-50905485-G-T	POLD1	c.613G>T	p.G205C	Missense	6/27	-
12-133245227-C-T	POLE	c.2020G>A	p.E674K	Missense	18/49	-
12-133226002-C-T	POLE	c.3895G>A	p.E1299K	Missense	31/49	-
12-133237686-C-T	POLE	c.2929G>A	p.G977R	Missense	25/49	-
12-133253971-C-A	POLE	c.779G>T	p.R260L	Missense	8/49	-
19-50902277-G-A	POLD1	c.169G>A	p.E57K	Missense	2/27	-
12-133220431-C-T	POLE	c.4282G>A	p.E1428K	Missense	33/49	-
12-133218868-C-T	POLE	c.5068G>A	p.A1690T	Missense	38/49	-
12-133256222-C-A	POLE	c.439G>T	p.G147C	Missense	6/49	-
12-133225957-C-A	POLE	c.3940G>T	p.G1314W	Missense	31/49	-
12-133220130-C-A	POLE	c.4307G>T	p.R1436L	Missense	34/49	-
12-133237701-C-G	POLE	c.2914G>C	p.E972Q	Missense	25/49	-
12-133256605-G-C	POLE	c.358C>G	p.L120V	Missense	5/49	-
12-133257242-C-A	POLE	c.236G>T	p.G79V	Missense	3/49	-
7-140434543-G-T	BRAF	c.2155C>A	p.R719S	Missense	18/18	-
3-178928274-C-A	PIK3CA	c.1460C>A	p.P487Q	Missense	9/21	-
7-140476855-C-A	BRAF	c.1551G>T	p.M517I	Missense	13/18	-
7-140453119-C-A	BRAF	c.1816G>T	p.G606W	Missense	15/18	-
7-140476818-G-T	BRAF	c.1588C>A	p.Q530K	Missense	13/18	-
7-140549992-C-A	BRAF	c.159G>T	p.M53I	Missense	2/18	-
7-55270263-C-A	EGFR	c.3216C>A	p.D1072E	Missense	27/28	-
12-133254296-C-A	POLE	c.588G>T	p.Q196H	Missense	7/49	-
7-140449113-A-C	BRAF	c.1966T>G	p.Y656D	Missense	16/18	-
19-50909554-G-A	POLD1	c.1358G>A	p.G453D	Missense	11/27	-
12-133202842-C-T	POLE	c.6392G>A	p.R2131H	Missense	46/49	-
12-133250255-T-C	POLE	c.1265A>G	p.H422R	Missense	13/49	-
12-133256212-C-T	POLE	c.449G>A	p.R150Q	Missense	6/49	-
12-133212563-C-T	POLE	c.5726G>A	p.R1909Q	Missense	42/49	-
12-133254282-A-G	POLE	c.602T>C	p.I201T	Missense	7/49	-
19-50909698-C-T	POLD1	c.1418C>T	p.T473M	Missense	12/27	-
12-133240694-G-C	POLE	c.2602C>G	p.L868V	Missense	23/49	-
12-133257206-C-T	POLE	c.272G>A	p.G91E	Missense	3/49	-
12-133208974-A-G	POLE	c.6257T>C	p.M2086T	Missense	45/49	-
12-133244194-C-G	POLE	c.2214G>C	p.K738N	Missense	20/49	-
19-50905272-C-G	POLD1	c.480C>G	p.H160Q	Missense	5/27	-
12-133245468-C-T	POLE	c.1852G>A	p.E618K	Missense	17/49	-
12-133249845-C-T	POLE	c.1378G>A	p.V460M	Missense	14/49	-
19-50902142-G-A	POLD1	c.34G>A	p.G12R	Missense	2/27	-
19-50919948-G-A	POLD1	c.3035G>A	p.C1012Y	Missense	24/27	-
12-133240967-G-C	POLE	c.2550C>G	p.I850M	Missense	22/49	-
12-133210915-T-C	POLE	c.5861A>G	p.D1954G	Missense	43/49	-
19-50905059-G-T	POLD1	c.341G>T	p.G114V	Missense	4/27	-
19-50919665-G-T	POLD1	c.2833G>T	p.V945L	Missense	23/27	-
19-50905986-G-A	POLD1	c.958G>A	p.A320T	Missense	8/27	-
12-133234500-C-G	POLE	c.3332G>C	p.R1111P	Missense	27/49	-
19-50919665-G-A	POLD1	c.2833G>A	p.V945M	Missense	23/27	-
12-133235885-C-T	POLE	c.3271G>A	p.E1091K	Missense	26/49	-
19-50919914-G-A	POLD1	c.3001G>A	p.G1001S	Missense	24/27	-
12-133210908-C-G	POLE	c.5868G>C	p.E1956D	Missense	43/49	-
12-133210908-C-A	POLE	c.5868G>T	p.E1956D	Missense	43/49	-
12-133220506-G-A	POLE	c.4207C>T	p.P1403S	Missense	33/49	-
12-133215747-C-A	POLE	c.5516G>T	p.R1839L	Missense	40/49	-
19-50921100-C-T	POLD1	c.3220C>T	p.R1074W	Missense	27/27	-
12-133252022-C-G	POLE	c.1188G>C	p.E396D	Missense	12/49	-
12-133252022-C-A	POLE	c.1188G>T	p.E396D	Missense	12/49	-
12-133249835-G-T	POLE	c.1388C>A	p.A463D	Missense	14/49	-
12-133257207-C-T	POLE	c.271G>A	p.G91R	Missense	3/49	-
12-133263853-C-T	POLE	c.49G>A	p.G17S	Missense	1/49	-
3-12626452-G-A	RAF1	c.1697C>T	p.A566V	Missense	16/17	-
12-133252754-C-T	POLE	c.946G>A	p.D316N	Missense	10/49	-
3-12627233-G-A	RAF1	c.1483C>T	p.R495C	Missense	14/17	-
12-133245307-T-A	POLE	c.1940A>T	p.D647V	Missense	18/49	-
12-133257746-C-T	POLE	c.182G>A	p.G61D	Missense	2/49	-
12-133238222-G-A	POLE	c.2755C>T	p.L919F	Missense	24/49	-
12-133252024-C-G	POLE	c.1186G>C	p.E396Q	Missense	12/49	-
12-133249810-C-G	POLE	c.1413G>C	p.M471I	Missense	14/49	-
12-133202337-T-C	POLE	c.6551A>G	p.Q2184R	Missense	47/49	-
12-133252334-C-T	POLE	c.1093G>A	p.D365N	Missense	11/49	-
12-133249810-C-T	POLE	c.1413G>A	p.M471I	Missense	14/49	-
12-133245030-G-T	POLE	c.2085C>A	p.F695L	Missense	19/49	-
12-133237707-C-T	POLE	c.2908G>A	p.G970S	Missense	25/49	-
12-133252736-A-G	POLE	c.964T>C	p.F322L	Missense	10/49	-
12-133253201-T-G	POLE	c.840A>C	p.K280N	Missense	9/49	-
12-133250181-T-C	POLE	c.1339A>G	p.M447V	Missense	13/49	-
12-133209065-C-A	POLE	c.6166G>T	p.A2056S	Missense	45/49	-
12-133212482-C-A	POLE	c.5807G>T	p.G1936V	Missense	42/49	-
12-133201348-C-T	POLE	c.6796G>A	p.G2266S	Missense	49/49	-
12-133201390-T-C	POLE	c.6754A>G	p.M2252V	Missense	49/49	-
12-133202287-T-C	POLE	c.6601A>G	p.M2201V	Missense	47/49	-
12-133202900-G-C	POLE	c.6334C>G	p.L2112V	Missense	46/49	-
12-133215756-G-A	POLE	c.5507C>T	p.A1836V	Missense	40/49	-
12-133218341-C-A	POLE	c.5270G>T	p.S1757I	Missense	39/49	-
12-133218811-C-T	POLE	c.5125G>A	p.D1709N	Missense	38/49	-
12-133219128-A-G	POLE	c.4916T>C	p.L1639P	Missense	37/49	-
12-133219848-G-C	POLE	c.4513C>G	p.P1505A	Missense	35/49	-
12-133219885-G-T	POLE	c.4476C>A	p.H1492Q	Missense	35/49	-
12-133219911-T-C	POLE	c.4450A>G	p.I1484V	Missense	35/49	-
12-133220520-T-C	POLE	c.4193A>G	p.Y1398C	Missense	33/49	-
12-133225938-C-T	POLE	c.3959G>A	p.R1320Q	Missense	31/49	-
12-133225971-T-C	POLE	c.3926A>G	p.D1309G	Missense	31/49	-
12-133240658-T-C	POLE	c.2638A>G	p.T880A	Missense	23/49	-
12-133244981-G-C	POLE	c.2134C>G	p.R712G	Missense	19/49	-
12-133245071-C-T	POLE	c.2044G>A	p.E682K	Missense	19/49	-
12-133248839-C-T	POLE	c.1756G>A	p.E586K	Missense	16/49	-
12-133249308-C-T	POLE	c.1591G>A	p.G531R	Missense	15/49	-
12-133249768-A-C	POLE	c.1455T>G	p.I485M	Missense	14/49	-
12-133250240-G-A	POLE	c.1280C>T	p.A427V	Missense	13/49	-
12-133252072-C-A	POLE	c.1138G>T	p.G380C	Missense	12/49	-
12-133257833-A-C	POLE	c.95T>G	p.L32R	Missense	2/49	-
19-50905112-G-A	POLD1	c.394G>A	p.D132N	Missense	4/27	-
19-50905473-T-C	POLD1	c.601T>C	p.Y201H	Missense	6/27	-
19-50906331-G-C	POLD1	c.992G>C	p.R331P	Missense	9/27	-
19-50906430-T-C	POLD1	c.1091T>C	p.L364P	Missense	9/27	-
19-50910252-C-G	POLD1	c.1507C>G	p.Q503E	Missense	13/27	-
19-50909563-A-T	POLD1	c.1367A>T	p.Q456L	Missense	11/27	-
19-50906412-G-A	POLD1	c.1073G>A	p.R358Q	Missense	9/27	-
19-50906806-C-G	POLD1	c.1194C>G	p.I398M	Missense	10/27	-
19-50916701-C-T	POLD1	c.2173C>T	p.R725C	Missense	18/27	-
19-50918080-C-A	POLD1	c.2397C>A	p.F799L	Missense	20/27	-
19-50918220-C-T	POLD1	c.2537C>T	p.A846V	Missense	20/27	-
19-50918243-G-T	POLD1	c.2560G>T	p.D854Y	Missense	20/27	-
19-50918247-G-T	POLD1	c.2564G>T	p.R855L	Missense	20/27	-
19-50919765-G-A	POLD1	c.2933G>A	p.R978H	Missense	23/27	-
19-50919773-G-T	POLD1	c.2941G>T	p.A981S	Missense	23/27	-
19-50919896-C-T	POLD1	c.2983C>T	p.L995F	Missense	24/27	-
19-50920329-G-A	POLD1	c.3095G>A	p.R1032Q	Missense	25/27	-
19-50921170-G-A	POLD1	c.3290G>A	p.R1097Q	Missense	27/27	-
19-50921173-G-T	POLD1	c.3293G>T	p.R1098L	Missense	27/27	-
12-133210810-G-C	POLE	c.5966C>G	p.A1989G	Missense	43/49	-
12-133220541-G-C	POLE	c.4172C>G	p.S1391C	Missense	33/49	-
12-133226089-C-T	POLE	c.3808G>A	p.V1270I	Missense	31/49	-
12-133245423-T-G	POLE	c.1897A>C	p.N633H	Missense	17/49	-
12-133252063-T-C	POLE	c.1147A>G	p.M383V	Missense	12/49	-
12-133256215-T-C	POLE	c.446A>G	p.K149R	Missense	6/49	-
12-133257816-T-A	POLE	c.112A>T	p.S38C	Missense	2/49	-
19-50906456-A-G	POLD1	c.1117A>G	p.K373E	Missense	9/27	-
19-50909466-G-T	POLD1	c.1270G>T	p.V424L	Missense	11/27	-
12-133238213-C-T	POLE	c.2764G>A	p.V922I	Missense	24/49	-
12-133252372-T-G	POLE	c.1055A>C	p.Q352P	Missense	11/49	-
12-133214720-A-G	POLE	c.5558T>C	p.I1853T	Missense	41/49	-
19-50917119-C-T	POLD1	c.2371C>T	p.R791W	Missense	19/27	-
12-133249349-G-A	POLE	c.1550C>T	p.P517L	Missense	15/49	-
19-50905896-G-A	POLD1	c.868G>A	p.V290M	Missense	8/27	-
12-133219152-C-A	POLE	c.4892G>T	p.R1631L	Missense	37/49	-
12-133238266-C-G	POLE	c.2711G>C	p.G904A	Missense	24/49	-
12-133209370-C-A	POLE	c.6016G>T	p.A2006S	Missense	44/49	-
19-50919936-G-A	POLD1	c.3023G>A	p.R1008H	Missense	24/27	-
19-50905279-G-T	POLD1	c.487G>T	p.D163Y	Missense	5/27	-
19-50910632-G-A	POLD1	c.1735G>A	p.E579K	Missense	14/27	-
12-133240610-T-C	POLE	c.2686A>G	p.M896V	Missense	23/49	-
12-133201300-G-T	POLE	c.6844C>A	p.P2282T	Missense	49/49	-
12-133209256-G-A	POLE	c.6130C>T	p.L2044F	Missense	44/49	-
12-133202305-C-T	POLE	c.6583G>A	p.D2195N	Missense	47/49	-
12-133225573-C-T	POLE	c.4091G>A	p.R1364H	Missense	32/49	-
12-133218815-C-A	POLE	c.5121G>T	p.E1707D	Missense	38/49	-
12-133218949-C-G	POLE	c.4987G>C	p.D1663H	Missense	38/49	-
12-133219847-G-A	POLE	c.4514C>T	p.P1505L	Missense	35/49	-
12-133226313-C-T	POLE	c.3745G>A	p.V1249M	Missense	30/49	-
12-133208919-G-C	POLE	c.6312C>G	p.F2104L	Missense	45/49	-
12-133208987-C-T	POLE	c.6244G>A	p.E2082K	Missense	45/49	-
12-133214667-T-C	POLE	c.5611A>G	p.I1871V	Missense	41/49	-
12-133215825-T-A	POLE	c.5438A>T	p.Y1813F	Missense	40/49	-
12-133226465-G-T	POLE	c.3593C>A	p.A1198D	Missense	30/49	-
12-133218336-C-T	POLE	c.5275G>A	p.D1759N	Missense	39/49	-
12-133219155-C-T	POLE	c.4889G>A	p.R1630Q	Missense	37/49	-
12-133218855-A-G	POLE	c.5081T>C	p.L1694P	Missense	38/49	-
12-133218874-G-A	POLE	c.5062C>T	p.P1688S	Missense	38/49	-
12-133225978-T-C	POLE	c.3919A>G	p.I1307V	Missense	31/49	-
12-133225605-A-C	POLE	c.4059T>G	p.S1353R	Missense	32/49	-
12-133226333-G-C	POLE	c.3725C>G	p.S1242C	Missense	30/49	-
12-133235887-G-A	POLE	c.3269C>T	p.T1090M	Missense	26/49	-
12-133235981-G-A	POLE	c.3175C>T	p.R1059C	Missense	26/49	-
12-133245017-G-A	POLE	c.2098C>T	p.P700S	Missense	19/49	-
12-133240601-T-C	POLE	c.2695A>G	p.I899V	Missense	23/49	-
12-133245076-C-A	POLE	c.2039G>T	p.R680L	Missense	19/49	-
12-133245522-A-T	POLE	c.1798T>A	p.C600S	Missense	17/49	-
12-133257219-T-C	POLE	c.259A>G	p.I87V	Missense	3/49	-
12-133215840-T-C	POLE	c.5423A>G	p.Q1808R	Missense	40/49	-
12-133245016-G-A	POLE	c.2099C>T	p.P700L	Missense	19/49	-
12-133218973-T-C	POLE	c.4963A>G	p.I1655V	Missense	38/49	-
12-133219192-T-C	POLE	c.4852A>G	p.N1618D	Missense	37/49	-
12-133225633-A-G	POLE	c.4031T>C	p.L1344P	Missense	32/49	-
12-133225652-C-T	POLE	c.4012G>A	p.E1338K	Missense	32/49	-
12-133252007-C-G	POLE	c.1203G>C	p.Q401H	Missense	12/49	-
12-133225921-T-C	POLE	c.3976A>G	p.I1326V	Missense	31/49	-
12-133257751-C-G	POLE	c.177G>C	p.K59N	Missense	2/49	-
12-133257803-T-A	POLE	c.125A>T	p.D42V	Missense	2/49	-
12-133242009-C-T	POLE	c.2347G>A	p.V783M	Missense	21/49	-
12-133242029-T-C	POLE	c.2327A>G	p.K776R	Missense	21/49	-
19-50909559-G-T	POLD1	c.1363G>T	p.V455L	Missense	11/27	-
12-133215871-T-C	POLE	c.5392A>G	p.M1798V	Missense	40/49	-
12-133218831-T-C	POLE	c.5105A>G	p.N1702S	Missense	38/49	-
12-133225981-C-T	POLE	c.3916G>A	p.A1306T	Missense	31/49	-
12-133225992-A-G	POLE	c.3905T>C	p.L1302P	Missense	31/49	-
12-133226363-T-G	POLE	c.3695A>C	p.K1232T	Missense	30/49	-
12-133245425-G-C	POLE	c.1895C>G	p.P632R	Missense	17/49	-
12-133249250-C-T	POLE	c.1649G>A	p.G550E	Missense	15/49	-
12-133254004-C-T	POLE	c.746G>A	p.R249Q	Missense	8/49	-
12-133256792-T-C	POLE	c.302A>G	p.K101R	Missense	4/49	-
12-133218880-G-C	POLE	c.5056C>G	p.L1686V	Missense	38/49	-
12-133219881-G-C	POLE	c.4480C>G	p.Q1494E	Missense	35/49	-
12-133220106-A-G	POLE	c.4331T>C	p.V1444A	Missense	34/49	-
12-133234455-G-A	POLE	c.3377C>T	p.A1126V	Missense	27/49	-
12-133249383-T-C	POLE	c.1516A>G	p.M506V	Missense	15/49	-
12-133249797-G-A	POLE	c.1426C>T	p.P476S	Missense	14/49	-
12-133254201-T-C	POLE	c.683A>G	p.Y228C	Missense	7/49	-
19-50905480-G-T	POLD1	c.608G>T	p.G203V	Missense	6/27	-
12-133252346-T-G	POLE	c.1081A>C	p.T361P	Missense	11/49	-
12-133214709-T-C	POLE	c.5569A>G	p.K1857E	Missense	41/49	-
12-133201377-C-G	POLE	c.6767G>C	p.G2256A	Missense	49/49	-
12-133263859-C-T	POLE	c.43G>A	p.A15T	Missense	1/49	-
12-133218374-T-C	POLE	c.5237A>G	p.N1746S	Missense	39/49	-
12-133208999-G-A	POLE	c.6232C>T	p.R2078W	Missense	45/49	-
12-133219255-C-T	POLE	c.4789G>A	p.A1597T	Missense	37/49	-
12-133209369-G-A	POLE	c.6017C>T	p.A2006V	Missense	44/49	-
12-133220443-C-T	POLE	c.4270G>A	p.E1424K	Missense	33/49	-
12-133220514-T-C	POLE	c.4199A>G	p.Y1400C	Missense	33/49	-
12-133220534-C-A	POLE	c.4179G>T	p.M1393I	Missense	33/49	-
12-133214712-A-G	POLE	c.5566T>C	p.F1856L	Missense	41/49	-
12-133226079-C-A	POLE	c.3818G>T	p.R1273L	Missense	31/49	-
12-133237727-C-T	POLE	c.2888G>A	p.G963D	Missense	25/49	-
12-133240687-T-C	POLE	c.2609A>G	p.N870S	Missense	23/49	-
12-133219836-T-C	POLE	c.4525A>G	p.R1509G	Missense	35/49	-
12-133244942-C-A	POLE	c.2173G>T	p.D725Y	Missense	19/49	-
12-133233811-C-T	POLE	c.3493G>A	p.D1165N	Missense	29/49	-
12-133245001-C-T	POLE	c.2114G>A	p.R705Q	Missense	19/49	-
12-133235933-T-A	POLE	c.3223A>T	p.S1075C	Missense	26/49	-
12-133235986-G-A	POLE	c.3170C>T	p.A1057V	Missense	26/49	-
12-133236084-C-A	POLE	c.3072G>T	p.M1024I	Missense	26/49	-
12-133237622-G-A	POLE	c.2993C>T	p.T998M	Missense	25/49	-
12-133252376-C-A	POLE	c.1051G>T	p.V351F	Missense	11/49	-
12-133252684-T-A	POLE	c.1016A>T	p.D339V	Missense	10/49	-
12-133240973-C-G	POLE	c.2544G>C	p.E848D	Missense	22/49	-
12-133254222-A-G	POLE	c.662T>C	p.M221T	Missense	7/49	-
12-133248854-C-T	POLE	c.1741G>A	p.A581T	Missense	16/49	-
19-50905357-G-T	POLD1	c.565G>T	p.A189S	Missense	5/27	-
19-50909469-G-T	POLD1	c.1273G>T	p.A425S	Missense	11/27	-
19-50912152-A-T	POLD1	c.1886A>T	p.K629I	Missense	15/27	-
19-50902286-T-C	POLD1	c.178T>C	p.S60P	Missense	2/27	-
19-50918760-A-G	POLD1	c.2630A>G	p.D877G	Missense	21/27	-
19-50917111-C-T	POLD1	c.2363C>T	p.S788L	Missense	19/27	-
19-50917090-G-T	POLD1	c.2342G>T	p.W781L	Missense	19/27	-
19-50919881-C-T	POLD1	c.2968C>T	p.R990C	Missense	24/27	-
19-50919923-G-A	POLD1	c.3010G>A	p.A1004T	Missense	24/27	-
19-50902262-G-A	POLD1	c.154G>A	p.E52K	Missense	2/27	-
19-50919046-G-C	POLD1	c.2783G>C	p.S928T	Missense	22/27	-
19-50919785-C-T	POLD1	c.2953C>T	p.R985W	Missense	23/27	-
12-133201387-C-G	POLE	c.6757G>C	p.E2253Q	Missense	49/49	-
19-50902145-G-A	POLD1	c.37G>A	p.V13M	Missense	2/27	-
19-50902145-G-T	POLD1	c.37G>T	p.V13L	Missense	2/27	-
19-50906347-G-T	POLD1	c.1008G>T	p.Q336H	Missense	9/27	-
12-133253132-C-G	POLE	c.909G>C	p.Q303H	Missense	9/49	-
19-50909497-C-G	POLD1	c.1301C>G	p.S434C	Missense	11/27	-
12-133220118-T-C	POLE	c.4319A>G	p.H1440R	Missense	34/49	-
12-133225602-G-T	POLE	c.4062C>A	p.D1354E	Missense	32/49	-
12-133241972-T-C	POLE	c.2384A>G	p.K795R	Missense	21/49	-
12-133249260-G-A	POLE	c.1639C>T	p.L547F	Missense	15/49	-
12-133249271-T-G	POLE	c.1628A>C	p.H543P	Missense	15/49	-
12-133249332-C-T	POLE	c.1567G>A	p.E523K	Missense	15/49	-
19-50912405-C-A	POLD1	c.1919C>A	p.T640N	Missense	16/27	-
19-50918246-C-G	POLD1	c.2563C>G	p.R855G	Missense	20/27	-
19-50918151-G-T	POLD1	c.2468G>T	p.R823L	Missense	20/27	-
19-50919021-G-A	POLD1	c.2758G>A	p.D920N	Missense	22/27	-
19-50919072-A-T	POLD1	c.2809A>T	p.M937L	Missense	22/27	-
19-50919902-G-A	POLD1	c.2989G>A	p.G997S	Missense	24/27	-
19-50921181-C-T	POLD1	c.3301C>T	p.P1101S	Missense	27/27	-
19-50902211-G-A	POLD1	c.103G>A	p.E35K	Missense	2/27	-
19-50902708-A-T	POLD1	c.283A>T	p.I95F	Missense	3/27	-
19-50905050-T-C	POLD1	c.332T>C	p.V111A	Missense	4/27	-
19-50909490-C-G	POLD1	c.1294C>G	p.R432G	Missense	11/27	-
19-50905478-C-A	POLD1	c.606C>A	p.H202Q	Missense	6/27	-
19-50905992-C-T	POLD1	c.964C>T	p.R322C	Missense	8/27	-
19-50906312-A-G	POLD1	c.973A>G	p.I325V	Missense	9/27	-
19-50905614-G-A	POLD1	c.742G>A	p.V248I	Missense	6/27	-
19-50912077-C-A	POLD1	c.1811C>A	p.S604Y	Missense	15/27	-
19-50912139-G-A	POLD1	c.1873G>A	p.G625R	Missense	15/27	-
19-50916716-A-C	POLD1	c.2188A>C	p.K730Q	Missense	18/27	-
19-50917088-C-G	POLD1	c.2340C>G	p.D780E	Missense	19/27	-
19-50918704-G-T	POLD1	c.2574G>T	p.E858D	Missense	21/27	-
19-50919057-G-C	POLD1	c.2794G>C	p.G932R	Missense	22/27	-
19-50919066-G-A	POLD1	c.2803G>A	p.A935T	Missense	22/27	-
19-50919891-C-T	POLD1	c.2978C>T	p.T993M	Missense	24/27	-
19-50919972-G-A	POLD1	c.3059G>A	p.S1020N	Missense	24/27	-
19-50905890-G-A	POLD1	c.862G>A	p.A288T	Missense	8/27	-
19-50906331-G-A	POLD1	c.992G>A	p.R331Q	Missense	9/27	-
19-50906453-G-A	POLD1	c.1114G>A	p.E372K	Missense	9/27	-
19-50910279-T-C	POLD1	c.1534T>C	p.C512R	Missense	13/27	-
19-50910259-G-A	POLD1	c.1514G>A	p.R505H	Missense	13/27	-
19-50912423-T-A	POLD1	c.1937T>A	p.F646Y	Missense	16/27	-
19-50912810-C-G	POLD1	c.2041C>G	p.L681V	Missense	17/27	-
12-133219232-C-G	POLE	c.4812G>C	p.E1604D	Missense	37/49	-
12-133236005-A-G	POLE	c.3151T>C	p.S1051P	Missense	26/49	-
12-133249847-G-C	POLE	c.1376C>G	p.S459C	Missense	14/49	-
12-133257239-C-T	POLE	c.239G>A	p.S80N	Missense	3/49	-
12-133225587-C-A	POLE	c.4077G>T	p.R1359S	Missense	32/49	-
12-133218942-G-A	POLE	c.4994C>T	p.S1665F	Missense	38/49	-
12-133209381-G-A	POLE	c.6005C>T	p.A2002V	Missense	44/49	-
12-133210862-C-T	POLE	c.5914G>A	p.V1972M	Missense	43/49	-
12-133210913-C-A	POLE	c.5863G>T	p.D1955Y	Missense	43/49	-
12-133244136-C-T	POLE	c.2272G>A	p.V758M	Missense	20/49	-
12-133219829-G-A	POLE	c.4532C>T	p.S1511F	Missense	35/49	-
12-133225541-C-A	POLE	c.4123G>T	p.A1375S	Missense	32/49	-
12-133248869-T-C	POLE	c.1726A>G	p.K576E	Missense	16/49	-
12-133249313-T-C	POLE	c.1586A>G	p.D529G	Missense	15/49	-
12-133252099-A-G	POLE	c.1111T>C	p.F371L	Missense	12/49	-
12-133254292-C-T	POLE	c.592G>A	p.G198S	Missense	7/49	-
12-133218384-G-A	POLE	c.5227C>T	p.H1743Y	Missense	39/49	-
12-133201524-G-C	POLE	c.6714C>G	p.C2238W	Missense	48/49	-
12-133208973-C-T	POLE	c.6258G>A	p.M2086I	Missense	45/49	-
12-133244100-C-G	POLE	c.2308G>C	p.G770R	Missense	20/49	-
12-133226436-T-G	POLE	c.3622A>C	p.S1208R	Missense	30/49	-
12-133256620-C-T	POLE	c.343G>A	p.E115K	Missense	5/49	-
12-133249379-A-G	POLE	c.1520T>C	p.V507A	Missense	15/49	-
19-50909704-A-G	POLD1	c.1424A>G	p.N475S	Missense	12/27	-
12-133220098-C-T	POLE	c.4339G>A	p.V1447I	Missense	34/49	-
12-133249359-T-C	POLE	c.1540A>G	p.I514V	Missense	15/49	-
12-133212531-A-G	POLE	c.5758T>C	p.S1920P	Missense	42/49	-
12-133215831-T-C	POLE	c.5432A>G	p.N1811S	Missense	40/49	-
12-133219575-C-T	POLE	c.4559G>A	p.S1520N	Missense	36/49	-
12-133225640-C-T	POLE	c.4024G>A	p.A1342T	Missense	32/49	-
12-133236067-A-T	POLE	c.3089T>A	p.F1030Y	Missense	26/49	-
12-133238266-C-A	POLE	c.2711G>T	p.G904V	Missense	24/49	-
12-133250179-C-T	POLE	c.1341G>A	p.M447I	Missense	13/49	-
12-133220497-T-C	POLE	c.4216A>G	p.M1406V	Missense	33/49	-
12-133225529-C-T	POLE	c.4135G>A	p.A1379T	Missense	32/49	-
12-133253984-C-T	POLE	c.766G>A	p.E256K	Missense	8/49	-
19-50910671-G-A	POLD1	c.1774G>A	p.G592R	Missense	14/27	-
19-50910671-G-C	POLD1	c.1774G>C	p.G592R	Missense	14/27	-
19-50912158-G-A	POLD1	c.1892G>A	p.G631D	Missense	15/27	-
19-50912431-A-C	POLD1	c.1945A>C	p.T649P	Missense	16/27	-
19-50918992-G-A	POLD1	c.2729G>A	p.R910Q	Missense	22/27	-
19-50919743-G-A	POLD1	c.2911G>A	p.E971K	Missense	23/27	-
12-133202783-A-T	POLE	c.6451T>A	p.Y2151N	Missense	46/49	-
19-50919724-G-C	POLD1	c.2892G>C	p.K964N	Missense	23/27	-
12-133209058-T-C	POLE	c.6173A>G	p.E2058G	Missense	45/49	-
12-133209357-C-T	POLE	c.6029G>A	p.C2010Y	Missense	44/49	-
12-133218248-C-T	POLE	c.5363G>A	p.C1788Y	Missense	39/49	-
12-133218294-C-T	POLE	c.5317G>A	p.G1773S	Missense	39/49	-
12-133218320-G-A	POLE	c.5291C>T	p.A1764V	Missense	39/49	-
12-133220536-T-C	POLE	c.4177A>G	p.M1393V	Missense	33/49	-
12-133225576-G-A	POLE	c.4088C>T	p.P1363L	Missense	32/49	-
12-133226446-A-C	POLE	c.3612T>G	p.S1204R	Missense	30/49	-
12-133240652-T-G	POLE	c.2644A>C	p.N882H	Missense	23/49	-
12-133254293-C-G	POLE	c.591G>C	p.R197S	Missense	7/49	-
12-133254293-C-A	POLE	c.591G>T	p.R197S	Missense	7/49	-
12-133250214-G-T	POLE	c.1306C>A	p.P436T	Missense	13/49	-
12-133256780-T-A	POLE	c.314A>T	p.Y105F	Missense	4/49	-
19-50918720-G-T	POLD1	c.2590G>T	p.A864S	Missense	21/27	-
19-50920307-G-C	POLD1	c.3073G>C	p.V1025L	Missense	25/27	-
12-133226412-C-T	POLE	c.3646G>A	p.G1216S	Missense	30/49	-
12-133248814-G-A	POLE	c.1781C>T	p.T594I	Missense	16/49	-
19-50917081-C-T	POLD1	c.2333C>T	p.A778V	Missense	19/27	-
19-50916725-C-G	POLD1	c.2197C>G	p.Q733E	Missense	18/27	-
19-50916764-A-G	POLD1	c.2236A>G	p.S746G	Missense	18/27	-
19-50919058-G-C	POLD1	c.2795G>C	p.G932A	Missense	22/27	-
19-50912380-C-A	POLD1	c.1894C>A	p.L632M	Missense	16/27	-
12-133201504-G-C	POLE	c.6734C>G	p.T2245S	Missense	48/49	-
12-133208945-G-C	POLE	c.6286C>G	p.L2096V	Missense	45/49	-
12-133214700-C-G	POLE	c.5578G>C	p.G1860R	Missense	41/49	-
12-133215771-A-G	POLE	c.5492T>C	p.L1831P	Missense	40/49	-
12-133218306-T-C	POLE	c.5305A>G	p.M1769V	Missense	39/49	-
12-133218768-G-A	POLE	c.5168C>T	p.S1723F	Missense	38/49	-
12-133219438-T-C	POLE	c.4696A>G	p.R1566G	Missense	36/49	-
12-133219851-T-A	POLE	c.4510A>T	p.I1504F	Missense	35/49	-
12-133219993-C-G	POLE	c.4444G>C	p.G1482R	Missense	34/49	-
12-133225972-C-T	POLE	c.3925G>A	p.D1309N	Missense	31/49	-
12-133226014-G-T	POLE	c.3883C>A	p.L1295M	Missense	31/49	-
12-133234524-G-T	POLE	c.3308C>A	p.P1103H	Missense	27/49	-
12-133236034-C-T	POLE	c.3122G>A	p.R1041Q	Missense	26/49	-
12-133202726-A-G	POLE	c.6508T>C	p.C2170R	Missense	46/49	-
12-133240618-G-A	POLE	c.2678C>T	p.P893L	Missense	23/49	-
12-133210937-C-T	POLE	c.5839G>A	p.E1947K	Missense	43/49	-
12-133245483-C-T	POLE	c.1837G>A	p.V613I	Missense	17/49	-
12-133214610-T-C	POLE	c.5668A>G	p.I1890V	Missense	41/49	-
12-133218431-A-T	POLE	c.5180T>A	p.V1727E	Missense	39/49	-
12-133220010-A-C	POLE	c.4427T>G	p.F1476C	Missense	34/49	-
12-133220484-T-G	POLE	c.4229A>C	p.H1410P	Missense	33/49	-
12-133253992-A-G	POLE	c.758T>C	p.F253S	Missense	8/49	-
12-133225541-C-T	POLE	c.4123G>A	p.A1375T	Missense	32/49	-
12-133226394-G-A	POLE	c.3664C>T	p.H1222Y	Missense	30/49	-
12-133241894-C-A	POLE	c.2462G>T	p.R821L	Missense	21/49	-
12-133244978-C-T	POLE	c.2137G>A	p.E713K	Missense	19/49	-
12-133248823-T-C	POLE	c.1772A>G	p.E591G	Missense	16/49	-
12-133250166-G-T	POLE	c.1354C>A	p.P452T	Missense	13/49	-
12-133252017-T-C	POLE	c.1193A>G	p.K398R	Missense	12/49	-
12-133256202-G-C	POLE	c.459C>G	p.I153M	Missense	6/49	-
12-133256608-A-G	POLE	c.355T>C	p.F119L	Missense	5/49	-
12-133257726-G-T	POLE	c.202C>A	p.P68T	Missense	2/49	-
12-133214687-A-G	POLE	c.5591T>C	p.I1864T	Missense	41/49	-
12-133215839-C-G	POLE	c.5424G>C	p.Q1808H	Missense	40/49	-
12-133218852-C-A	POLE	c.5084G>T	p.G1695V	Missense	38/49	-
12-133219309-G-C	POLE	c.4735C>G	p.R1579G	Missense	37/49	-
12-133210931-C-T	POLE	c.5845G>A	p.E1949K	Missense	43/49	-
12-133225552-C-T	POLE	c.4112G>A	p.R1371Q	Missense	32/49	-
19-50902160-G-A	POLD1	c.52G>A	p.A18T	Missense	2/27	-
19-50910591-A-C	POLD1	c.1694A>C	p.H565P	Missense	14/27	-
19-50918146-C-A	POLD1	c.2463C>A	p.H821Q	Missense	20/27	-
19-50918247-G-A	POLD1	c.2564G>A	p.R855Q	Missense	20/27	-
19-50919081-G-A	POLD1	c.2818G>A	p.E940K	Missense	22/27	-
19-50919732-T-C	POLD1	c.2900T>C	p.L967P	Missense	23/27	-
19-50921117-C-A	POLD1	c.3237C>A	p.F1079L	Missense	27/27	-
12-133219860-C-T	POLE	c.4501G>A	p.G1501R	Missense	35/49	-
12-133226321-G-C	POLE	c.3737C>G	p.T1246R	Missense	30/49	-
12-133219117-G-C	POLE	c.4927C>G	p.L1643V	Missense	37/49	-
12-133219137-T-G	POLE	c.4907A>C	p.Y1636S	Missense	37/49	-
12-133219488-G-C	POLE	c.4646C>G	p.P1549R	Missense	36/49	-
12-133245076-C-T	POLE	c.2039G>A	p.R680H	Missense	19/49	-
12-133226034-G-A	POLE	c.3863C>T	p.A1288V	Missense	31/49	-
12-133226333-G-A	POLE	c.3725C>T	p.S1242F	Missense	30/49	-
12-133249362-T-C	POLE	c.1537A>G	p.N513D	Missense	15/49	-
12-133234504-G-T	POLE	c.3328C>A	p.L1110I	Missense	27/49	-
12-133235909-T-G	POLE	c.3247A>C	p.K1083Q	Missense	26/49	-
12-133253999-T-A	POLE	c.751A>T	p.N251Y	Missense	8/49	-
12-133237728-C-T	POLE	c.2887G>A	p.G963S	Missense	25/49	-
12-133254174-T-C	POLE	c.710A>G	p.K237R	Missense	7/49	-
12-133256556-T-C	POLE	c.407A>G	p.K136R	Missense	5/49	-
12-133257726-G-C	POLE	c.202C>G	p.P68A	Missense	2/49	-
12-133257761-G-A	POLE	c.167C>T	p.P56L	Missense	2/49	-
12-133257860-T-C	POLE	c.68A>G	p.D23G	Missense	2/49	-
12-133241994-C-T	POLE	c.2362G>A	p.A788T	Missense	21/49	-
12-133245248-T-G	POLE	c.1999A>C	p.M667L	Missense	18/49	-
12-133249818-G-C	POLE	c.1405C>G	p.L469V	Missense	14/49	-
12-133202298-G-A	POLE	c.6590C>T	p.S2197F	Missense	47/49	-
12-133234465-C-G	POLE	c.3367G>C	p.D1123H	Missense	27/49	-
12-133236014-C-T	POLE	c.3142G>A	p.E1048K	Missense	26/49	-
19-50902210-C-A	POLD1	c.102C>A	p.F34L	Missense	2/27	-
19-50919885-G-A	POLD1	c.2972G>A	p.C991Y	Missense	24/27	-
19-50906330-C-T	POLD1	c.991C>T	p.R331W	Missense	9/27	-
19-50910319-G-A	POLD1	c.1574G>A	p.R525Q	Missense	13/27	-
19-50910614-G-T	POLD1	c.1717G>T	p.V573L	Missense	14/27	-
19-50912445-G-C	POLD1	c.1959G>C	p.K653N	Missense	16/27	-
19-50912807-C-G	POLD1	c.2038C>G	p.P680A	Missense	17/27	-
19-50918141-G-T	POLD1	c.2458G>T	p.A820S	Missense	20/27	-
19-50919007-C-T	POLD1	c.2744C>T	p.A915V	Missense	22/27	-
19-50921122-T-A	POLD1	c.3242T>A	p.M1081K	Missense	27/27	-
19-50906759-A-G	POLD1	c.1147A>G	p.T383A	Missense	10/27	-
19-50912419-G-A	POLD1	c.1933G>A	p.E645K	Missense	16/27	-
19-50917068-C-G	POLD1	c.2320C>G	p.L774V	Missense	19/27	-
19-50919052-C-T	POLD1	c.2789C>T	p.A930V	Missense	22/27	-
19-50919060-G-T	POLD1	c.2797G>T	p.V933L	Missense	22/27	-
19-50905923-C-T	POLD1	c.895C>T	p.P299S	Missense	8/27	-
19-50906457-A-G	POLD1	c.1118A>G	p.K373R	Missense	9/27	-
19-50916752-G-C	POLD1	c.2224G>C	p.E742Q	Missense	18/27	-
19-50918201-G-A	POLD1	c.2518G>A	p.V840M	Missense	20/27	-
19-50919656-C-T	POLD1	c.2824C>T	p.P942S	Missense	23/27	-
19-50921169-C-T	POLD1	c.3289C>T	p.R1097W	Missense	27/27	-
19-50905176-C-T	POLD1	c.458C>T	p.P153L	Missense	4/27	-
19-50905336-C-A	POLD1	c.544C>A	p.L182M	Missense	5/27	-
19-50905355-T-G	POLD1	c.563T>G	p.L188R	Missense	5/27	-
12-133210864-T-C	POLE	c.5912A>G	p.N1971S	Missense	43/49	-
19-50905998-G-T	POLD1	c.970G>T	p.G324C	Missense	8/27	-
19-50909506-A-G	POLD1	c.1310A>G	p.Q437R	Missense	11/27	-
19-50920478-A-G	POLD1	c.3170A>G	p.Q1057R	Missense	26/27	-
19-50920505-A-G	POLD1	c.3197A>G	p.H1066R	Missense	26/27	-
12-133244172-T-C	POLE	c.2236A>G	p.I746V	Missense	20/49	-
19-50910385-T-C	POLD1	c.1640T>C	p.L547P	Missense	13/27	-
19-50916746-A-G	POLD1	c.2218A>G	p.T740A	Missense	18/27	-
12-133220451-G-A	POLE	c.4262C>T	p.P1421L	Missense	33/49	-
12-133240986-G-A	POLE	c.2531C>T	p.T844I	Missense	22/49	-
12-133236040-A-G	POLE	c.3116T>C	p.M1039T	Missense	26/49	-
19-50906789-A-G	POLD1	c.1177A>G	p.I393V	Missense	10/27	-
12-133210903-T-C	POLE	c.5873A>G	p.E1958G	Missense	43/49	-
12-133202335-A-G	POLE	c.6553T>C	p.W2185R	Missense	47/49	-
12-133202795-G-A	POLE	c.6439C>T	p.P2147S	Missense	46/49	-
12-133208968-G-A	POLE	c.6263C>T	p.P2088L	Missense	45/49	-
12-133220132-G-T	POLE	c.4305C>A	p.F1435L	Missense	34/49	-
12-133219566-A-G	POLE	c.4568T>C	p.M1523T	Missense	36/49	-
12-133220022-G-A	POLE	c.4415C>T	p.S1472F	Missense	34/49	-
12-133218357-C-G	POLE	c.5254G>C	p.D1752H	Missense	39/49	-
12-133220038-G-T	POLE	c.4399C>A	p.H1467N	Missense	34/49	-
12-133218900-C-T	POLE	c.5036G>A	p.R1679H	Missense	38/49	-
12-133244187-C-T	POLE	c.2221G>A	p.E741K	Missense	20/49	-
12-133225613-C-G	POLE	c.4051G>C	p.V1351L	Missense	32/49	-
12-133241039-C-A	POLE	c.2478G>T	p.W826C	Missense	22/49	-
12-133233971-G-C	POLE	c.3423C>G	p.I1141M	Missense	28/49	-
12-133242021-G-A	POLE	c.2335C>T	p.L779F	Missense	21/49	-
12-133226301-C-G	POLE	c.3757G>C	p.E1253Q	Missense	30/49	-
12-133237686-C-G	POLE	c.2929G>C	p.G977R	Missense	25/49	-
12-133225656-G-C	POLE	c.4008C>G	p.I1336M	Missense	32/49	-
12-133245002-G-C	POLE	c.2113C>G	p.R705G	Missense	19/49	-
12-133245087-C-A	POLE	c.2028G>T	p.M676I	Missense	19/49	-
12-133254198-T-G	POLE	c.686A>C	p.H229P	Missense	7/49	-
12-133249425-C-T	POLE	c.1474G>A	p.V492M	Missense	15/49	-
19-50910251-C-A	POLD1	c.1506C>A	p.D502E	Missense	13/27	-
12-133256151-G-C	POLE	c.510C>G	p.I170M	Missense	6/49	-
12-133257210-C-T	POLE	c.268G>A	p.D90N	Missense	3/49	-
12-133254286-C-T	POLE	c.598G>A	p.V200I	Missense	7/49	-
19-50910415-C-T	POLD1	c.1670C>T	p.S557F	Missense	13/27	-
19-50902217-G-A	POLD1	c.109G>A	p.D37N	Missense	2/27	-
19-50902197-G-T	POLD1	c.89G>T	p.R30L	Missense	2/27	-
19-50921137-G-C	POLD1	c.3257G>C	p.R1086P	Missense	27/27	-
19-50906754-G-C	POLD1	c.1142G>C	p.W381S	Missense	10/27	-
19-50905789-G-T	POLD1	c.837G>T	p.E279D	Missense	7/27	-
19-50906355-C-T	POLD1	c.1016C>T	p.S339L	Missense	9/27	-
19-50906310-G-A	POLD1	c.971G>A	p.G324D	Missense	9/27	-
19-50905530-G-T	POLD1	c.658G>T	p.V220L	Missense	6/27	-
19-50921123-G-A	POLD1	c.3243G>A	p.M1081I	Missense	27/27	-
19-50916713-G-C	POLD1	c.2185G>C	p.E729Q	Missense	18/27	-
19-50918133-G-T	POLD1	c.2450G>T	p.R817L	Missense	20/27	-
19-50919698-T-C	POLD1	c.2866T>C	p.Y956H	Missense	23/27	-
19-50920466-G-A	POLD1	c.3158G>A	p.R1053H	Missense	26/27	-
12-133254199-G-A	POLE	c.685C>T	p.H229Y	Missense	7/49	-
3-30686271-G-T	TGFBR2	c.127G>T	p.G43C	Missense	2/7	-
7-128846351-A-G	SMO	c.1187A>G	p.N396S	Missense	6/12	-
12-133241988-C-T	POLE	c.2368G>A	p.E790K	Missense	21/49	-
12-133252337-C-A	POLE	c.1090G>T	p.G364W	Missense	11/49	-
12-133250241-C-A	POLE	c.1279G>T	p.A427S	Missense	13/49	-
12-133233733-C-A	POLE	c.3571G>T	p.G1191C	Missense	29/49	-
12-133253969-C-T	POLE	c.781G>A	p.D261N	Missense	8/49	-
12-133220553-A-G	POLE	c.4160T>C	p.V1387A	Missense	33/49	-
12-133208909-C-G	POLE	c.6322G>C	p.V2108L	Missense	45/49	-
1-9782066-G-T	PIK3CD	c.2089G>T	p.D697Y	Missense	17/24	-
12-133225515-C-G	POLE	c.4149G>C	p.K1383N	Missense	32/49	-
12-133250177-G-A	POLE	c.1343C>T	p.A448V	Missense	13/49	-
12-133254296-C-G	POLE	c.588G>C	p.Q196H	Missense	7/49	-
12-133252406-C-T	POLE	c.1021G>A	p.A341T	Missense	11/49	-
12-133238243-C-G	POLE	c.2734G>C	p.E912Q	Missense	24/49	-
12-133225515-C-A	POLE	c.4149G>T	p.K1383N	Missense	32/49	-
12-133238150-G-A	POLE	c.2827C>T	p.P943S	Missense	24/49	-
12-133220509-C-T	POLE	c.4204G>A	p.V1402M	Missense	33/49	-
12-133219494-G-A	POLE	c.4640C>T	p.P1547L	Missense	36/49	-
12-133245035-T-C	POLE	c.2080A>G	p.K694E	Missense	19/49	-
12-133210782-C-G	POLE	c.5994G>C	p.M1998I	Missense	43/49	-
12-133210782-C-T	POLE	c.5994G>A	p.M1998I	Missense	43/49	-
12-133210782-C-A	POLE	c.5994G>T	p.M1998I	Missense	43/49	-
12-133237614-C-G	POLE	c.3001G>C	p.E1001Q	Missense	25/49	-
12-133225904-C-A	POLE	c.3993G>T	p.W1331C	Missense	31/49	-
12-133253136-C-T	POLE	c.905G>A	p.G302D	Missense	9/49	-
12-133219425-C-T	POLE	c.4709G>A	p.R1570Q	Missense	36/49	-
12-133225904-C-G	POLE	c.3993G>C	p.W1331C	Missense	31/49	-
3-12632402-T-C	RAF1	c.1265A>G	p.Q422R	Missense	12/17	-
12-133202837-C-G	POLE	c.6397G>C	p.V2133L	Missense	46/49	-
12-133202837-C-A	POLE	c.6397G>T	p.V2133L	Missense	46/49	-
12-133240645-T-C	POLE	c.2651A>G	p.K884R	Missense	23/49	-
12-133256141-C-T	POLE	c.520G>A	p.V174M	Missense	6/49	-
12-133237629-C-T	POLE	c.2986G>A	p.G996S	Missense	25/49	-
19-50917120-G-T	POLD1	c.2372G>T	p.R791L	Missense	19/27	-
12-133210919-C-T	POLE	c.5857G>A	p.E1953K	Missense	43/49	-
12-133257207-C-G	POLE	c.271G>C	p.G91R	Missense	3/49	-
X-47428415-G-A	ARAF	c.1283G>A	p.R428Q	Missense	12/16	-
12-133263846-G-T	POLE	c.56C>A	p.A19D	Missense	1/49	-
8-38277193-C-T	FGFR1	c.1142G>A	p.C381Y	Missense	9/18	-
19-50902160-G-T	POLD1	c.52G>T	p.A18S	Missense	2/27	-
3-12647752-G-A	RAF1	c.628C>T	p.P210S	Missense	6/17	-
19-50905625-G-C	POLD1	c.753G>C	p.E251D	Missense	6/27	-
19-50905625-G-T	POLD1	c.753G>T	p.E251D	Missense	6/27	-
X-47429037-C-T	ARAF	c.1400C>T	p.S467L	Missense	13/16	-
12-133208951-G-A	POLE	c.6280C>T	p.H2094Y	Missense	45/49	-
12-133201291-C-T	POLE	c.6853G>A	p.G2285S	Missense	49/49	-
12-133245005-C-G	POLE	c.2110G>C	p.A704P	Missense	19/49	-
12-133249254-A-C	POLE	c.1645T>G	p.S549A	Missense	15/49	-
12-133226002-C-G	POLE	c.3895G>C	p.E1299Q	Missense	31/49	-
12-133240613-C-A	POLE	c.2683G>T	p.A895S	Missense	23/49	-
17-37882093-G-C	ERBB2	c.2859G>C	p.M953I	Missense	23/27	-
17-37882093-G-T	ERBB2	c.2859G>T	p.M953I	Missense	23/27	-
19-50921191-C-T	POLD1	c.3311C>T	p.P1104L	Missense	27/27	-
12-133237572-C-T	POLE	c.3043G>A	p.D1015N	Missense	25/49	-
12-133240619-G-A	POLE	c.2677C>T	p.P893S	Missense	23/49	-
12-133248872-C-G	POLE	c.1723G>C	p.E575Q	Missense	16/49	-
12-133219525-G-A	POLE	c.4609C>T	p.L1537F	Missense	36/49	-
12-133240996-T-C	POLE	c.2521A>G	p.N841D	Missense	22/49	-
12-133201562-C-G	POLE	c.6676G>C	p.G2226R	Missense	48/49	-
12-133249308-C-G	POLE	c.1591G>C	p.G531R	Missense	15/49	-
12-133201500-G-C	POLE	c.6738C>G	p.I2246M	Missense	48/49	-
19-50916698-G-A	POLD1	c.2170G>A	p.G724R	Missense	18/27	-
19-50916698-G-C	POLD1	c.2170G>C	p.G724R	Missense	18/27	-
19-50902690-C-T	POLD1	c.265C>T	p.P89S	Missense	3/27	-
19-50909451-C-T	POLD1	c.1255C>T	p.P419S	Missense	11/27	-
19-50918195-C-T	POLD1	c.2512C>T	p.P838S	Missense	20/27	-
19-50910609-C-T	POLD1	c.1712C>T	p.P571L	Missense	14/27	-
19-50919665-G-C	POLD1	c.2833G>C	p.V945L	Missense	23/27	-
19-50902667-G-C	POLD1	c.242G>C	p.R81P	Missense	3/27	-
19-50918174-G-T	POLD1	c.2491G>T	p.A831S	Missense	20/27	-
19-50910270-G-C	POLD1	c.1525G>C	p.A509P	Missense	13/27	-
19-50921115-T-C	POLD1	c.3235T>C	p.F1079L	Missense	27/27	-
19-50921117-C-G	POLD1	c.3237C>G	p.F1079L	Missense	27/27	-
19-50919912-G-A	POLD1	c.2999G>A	p.G1000D	Missense	24/27	-
19-50909559-G-C	POLD1	c.1363G>C	p.V455L	Missense	11/27	-
19-50912781-A-T	POLD1	c.2012A>T	p.K671M	Missense	17/27	-
19-50910347-G-C	POLD1	c.1602G>C	p.E534D	Missense	13/27	-
19-50906423-C-T	POLD1	c.1084C>T	p.P362S	Missense	9/27	-
19-50920463-C-T	POLD1	c.3155C>T	p.S1052L	Missense	26/27	-
19-50905617-G-T	POLD1	c.745G>T	p.D249Y	Missense	6/27	-
19-50902142-G-C	POLD1	c.34G>C	p.G12R	Missense	2/27	-
19-50909524-G-A	POLD1	c.1328G>A	p.R443Q	Missense	11/27	-
19-50909689-G-A	POLD1	c.1409G>A	p.R470H	Missense	12/27	-
19-50920463-C-G	POLD1	c.3155C>G	p.S1052W	Missense	26/27	-
19-50902705-C-T	POLD1	c.280C>T	p.L94F	Missense	3/27	-
19-50920518-C-G	POLD1	c.3210C>G	p.I1070M	Missense	26/27	-
19-50905325-G-T	POLD1	c.533G>T	p.G178V	Missense	5/27	-
19-50912413-G-T	POLD1	c.1927G>T	p.G643W	Missense	16/27	-
19-50919735-G-A	POLD1	c.2903G>A	p.R968H	Missense	23/27	-
19-50905058-G-T	POLD1	c.340G>T	p.G114W	Missense	4/27	-
19-50918180-C-T	POLD1	c.2497C>T	p.R833C	Missense	20/27	-
19-50919746-C-T	POLD1	c.2914C>T	p.P972S	Missense	23/27	-
19-50902287-C-T	POLD1	c.179C>T	p.S60L	Missense	2/27	-
19-50916759-G-T	POLD1	c.2231G>T	p.G744V	Missense	18/27	-
19-50905712-T-C	POLD1	c.760T>C	p.F254L	Missense	7/27	-
19-50905714-C-A	POLD1	c.762C>A	p.F254L	Missense	7/27	-
19-50905714-C-G	POLD1	c.762C>G	p.F254L	Missense	7/27	-
19-50918704-G-C	POLD1	c.2574G>C	p.E858D	Missense	21/27	-
12-133252026-C-A	POLE	c.1184G>T	p.G395V	Missense	12/49	-
12-133225984-C-A	POLE	c.3913G>T	p.G1305W	Missense	31/49	-
12-133225535-C-T	POLE	c.4129G>A	p.E1377K	Missense	32/49	-
12-133218348-C-A	POLE	c.5263G>T	p.G1755W	Missense	39/49	-
12-133235903-C-T	POLE	c.3253G>A	p.E1085K	Missense	26/49	-
12-133235905-G-A	POLE	c.3251C>T	p.P1084L	Missense	26/49	-
12-133257725-G-A	POLE	c.203C>T	p.P68L	Missense	2/49	-
12-133218864-C-T	POLE	c.5072G>A	p.R1691H	Missense	38/49	-
12-133249757-G-A	POLE	c.1466C>T	p.P489L	Missense	14/49	-
12-133237655-G-A	POLE	c.2960C>T	p.S987F	Missense	25/49	-
12-133215791-C-G	POLE	c.5472G>C	p.W1824C	Missense	40/49	-
12-133212500-G-A	POLE	c.5789C>T	p.S1930L	Missense	42/49	-
12-133238113-C-A	POLE	c.2864G>T	p.R955M	Missense	24/49	-
12-133218763-C-G	POLE	c.5173G>C	p.V1725L	Missense	38/49	-
12-133218763-C-A	POLE	c.5173G>T	p.V1725L	Missense	38/49	-
12-133218976-G-A	POLE	c.4960C>T	p.H1654Y	Missense	38/49	-
12-133241924-A-G	POLE	c.2432T>C	p.I811T	Missense	21/49	-
12-133210787-G-A	POLE	c.5989C>T	p.L1997F	Missense	43/49	-
12-133209083-A-G	POLE	c.6148T>C	p.F2050L	Missense	45/49	-
12-133209081-G-T	POLE	c.6150C>A	p.F2050L	Missense	45/49	-
12-133209081-G-C	POLE	c.6150C>G	p.F2050L	Missense	45/49	-
12-133235974-G-A	POLE	c.3182C>T	p.A1061V	Missense	26/49	-
12-133218317-G-A	POLE	c.5294C>T	p.S1765F	Missense	39/49	-
12-133245030-G-C	POLE	c.2085C>G	p.F695L	Missense	19/49	-
12-133226031-C-A	POLE	c.3866G>T	p.R1289L	Missense	31/49	-
12-133242011-G-A	POLE	c.2345C>T	p.A782V	Missense	21/49	-
12-133249269-C-G	POLE	c.1630G>C	p.V544L	Missense	15/49	-
12-133249269-C-A	POLE	c.1630G>T	p.V544L	Missense	15/49	-
12-133202288-C-A	POLE	c.6600G>T	p.E2200D	Missense	47/49	-
12-133220067-C-T	POLE	c.4370G>A	p.G1457D	Missense	34/49	-
12-133233952-G-A	POLE	c.3442C>T	p.P1148S	Missense	28/49	-
12-133244194-C-A	POLE	c.2214G>T	p.K738N	Missense	20/49	-
12-133250267-G-A	POLE	c.1253C>T	p.P418L	Missense	13/49	-
12-133245011-C-G	POLE	c.2104G>C	p.G702R	Missense	19/49	-
19-50902708-A-G	POLD1	c.283A>G	p.I95V	Missense	3/27	-
12-133225587-C-G	POLE	c.4077G>C	p.R1359S	Missense	32/49	-
19-50902210-C-G	POLD1	c.102C>G	p.F34L	Missense	2/27	-
12-133257813-G-T	POLE	c.115C>A	p.Q39K	Missense	2/49	-
12-133263866-G-C	POLE	c.36C>G	p.D12E	Missense	1/49	-
12-133263866-G-T	POLE	c.36C>A	p.D12E	Missense	1/49	-
12-133257799-C-G	POLE	c.129G>C	p.K43N	Missense	2/49	-
12-133257799-C-A	POLE	c.129G>T	p.K43N	Missense	2/49	-
12-133257796-C-G	POLE	c.132G>C	p.M44I	Missense	2/49	-
12-133257796-C-T	POLE	c.132G>A	p.M44I	Missense	2/49	-
12-133257796-C-A	POLE	c.132G>T	p.M44I	Missense	2/49	-
12-133257814-A-C	POLE	c.114T>G	p.S38R	Missense	2/49	-
12-133257814-A-T	POLE	c.114T>A	p.S38R	Missense	2/49	-
12-133257816-T-G	POLE	c.112A>C	p.S38R	Missense	2/49	-
12-133257842-A-T	POLE	c.86T>A	p.V29D	Missense	2/49	-
12-133263852-C-G	POLE	c.50G>C	p.G17A	Missense	1/49	-
12-133257848-G-A	POLE	c.80C>T	p.S27F	Missense	2/49	-
12-133263843-C-A	POLE	c.59G>T	p.S20I	Missense	1/49	-
12-133263841-T-C	POLE	c.61A>G	p.R21G	Missense	1/49	-
12-133256549-A-C	POLE	c.414T>G	p.D138E	Missense	5/49	-
12-133256549-A-T	POLE	c.414T>A	p.D138E	Missense	5/49	-
12-133257742-C-G	POLE	c.186G>C	p.W62C	Missense	2/49	-
12-133257777-C-G	POLE	c.151G>C	p.E51Q	Missense	2/49	-
12-133256594-C-G	POLE	c.369G>C	p.K123N	Missense	5/49	-
12-133256617-C-T	POLE	c.346G>A	p.V116I	Missense	5/49	-
12-133256236-G-A	POLE	c.425C>T	p.P142L	Missense	6/49	-
12-133257227-T-C	POLE	c.251A>G	p.Y84C	Missense	3/49	-
12-133257788-C-A	POLE	c.140G>T	p.R47L	Missense	2/49	-
12-133256554-C-T	POLE	c.409G>A	p.E137K	Missense	5/49	-
12-133256599-T-C	POLE	c.364A>G	p.K122E	Missense	5/49	-
12-133257773-C-A	POLE	c.155G>T	p.R52L	Missense	2/49	-
12-133257758-C-A	POLE	c.170G>T	p.G57V	Missense	2/49	-
12-133257730-C-G	POLE	c.198G>C	p.M66I	Missense	2/49	-
12-133257730-C-A	POLE	c.198G>T	p.M66I	Missense	2/49	-
12-133256550-T-C	POLE	c.413A>G	p.D138G	Missense	5/49	-
12-133257228-A-G	POLE	c.250T>C	p.Y84H	Missense	3/49	-
12-133257258-C-T	POLE	c.220G>A	p.E74K	Missense	3/49	-
12-133256606-A-T	POLE	c.357T>A	p.F119L	Missense	5/49	-
12-133256606-A-C	POLE	c.357T>G	p.F119L	Missense	5/49	-
12-133256775-C-A	POLE	c.319G>T	p.A107S	Missense	4/49	-
12-133257231-C-T	POLE	c.247G>A	p.D83N	Missense	3/49	-
12-133257738-T-C	POLE	c.190A>G	p.I64V	Missense	2/49	-
12-133256607-A-G	POLE	c.356T>C	p.F119S	Missense	5/49	-
12-133257253-A-C	POLE	c.225T>G	p.D75E	Missense	3/49	-
12-133257253-A-T	POLE	c.225T>A	p.D75E	Missense	3/49	-
12-133257272-G-C	POLE	c.206C>G	p.T69S	Missense	3/49	-
12-133257273-T-A	POLE	c.205A>T	p.T69S	Missense	3/49	-
12-133257751-C-A	POLE	c.177G>T	p.K59N	Missense	2/49	-
12-133256784-A-T	POLE	c.310T>A	p.F104I	Missense	4/49	-
12-133256221-C-A	POLE	c.440G>T	p.G147V	Missense	6/49	-
12-133256624-C-G	POLE	c.339G>C	p.E113D	Missense	5/49	-
12-133256624-C-A	POLE	c.339G>T	p.E113D	Missense	5/49	-
12-133257210-C-A	POLE	c.268G>T	p.D90Y	Missense	3/49	-
12-133257204-T-C	POLE	c.274A>G	p.S92G	Missense	3/49	-
12-133256161-C-G	POLE	c.500G>C	p.R167T	Missense	6/49	-
12-133256575-T-C	POLE	c.388A>G	p.K130E	Missense	5/49	-
12-133257197-A-T	POLE	c.281T>A	p.F94Y	Missense	3/49	-
12-133256236-G-T	POLE	c.425C>A	p.P142Q	Missense	6/49	-
12-133256149-G-A	POLE	c.512C>T	p.S171F	Missense	6/49	-
12-133257193-C-G	POLE	c.285G>C	p.K95N	Missense	3/49	-
12-133257193-C-A	POLE	c.285G>T	p.K95N	Missense	3/49	-
12-133256804-G-C	POLE	c.290C>G	p.A97G	Missense	4/49	-
12-133256589-T-G	POLE	c.374A>C	p.Q125P	Missense	5/49	-
12-133256569-C-G	POLE	c.394G>C	p.E132Q	Missense	5/49	-
12-133256583-T-A	POLE	c.380A>T	p.K127I	Missense	5/49	-
12-133256563-C-T	POLE	c.400G>A	p.V134I	Missense	5/49	-
12-133256578-C-T	POLE	c.385G>A	p.A129T	Missense	5/49	-
12-133257251-T-A	POLE	c.227A>T	p.K76M	Missense	3/49	-
12-133256230-T-A	POLE	c.431A>T	p.H144L	Missense	6/49	-
12-133256792-T-A	POLE	c.302A>T	p.K101I	Missense	4/49	-
12-133257798-T-C	POLE	c.130A>G	p.M44V	Missense	2/49	-
12-133254261-G-C	POLE	c.623C>G	p.S208C	Missense	7/49	-
12-133254186-G-A	POLE	c.698C>T	p.S233F	Missense	7/49	-
12-133254271-C-G	POLE	c.613G>C	p.E205Q	Missense	7/49	-
12-133254250-C-G	POLE	c.634G>C	p.A212P	Missense	7/49	-
12-133254235-T-G	POLE	c.649A>C	p.N217H	Missense	7/49	-
12-133254213-T-A	POLE	c.671A>T	p.Y224F	Missense	7/49	-
12-133254237-T-C	POLE	c.647A>G	p.D216G	Missense	7/49	-
12-133253971-C-G	POLE	c.779G>C	p.R260P	Missense	8/49	-
12-133254268-C-T	POLE	c.616G>A	p.E206K	Missense	7/49	-
12-133253963-G-T	POLE	c.787C>A	p.L263I	Missense	8/49	-
12-133253167-G-T	POLE	c.874C>A	p.Q292K	Missense	9/49	-
12-133252781-T-G	POLE	c.919A>C	p.I307L	Missense	10/49	-
12-133254264-G-A	POLE	c.620C>T	p.T207I	Missense	7/49	-
12-133252786-T-A	POLE	c.914A>T	p.Y305F	Missense	10/49	-
12-133253170-C-A	POLE	c.871G>T	p.D291Y	Missense	9/49	-
12-133252790-C-T	POLE	c.910G>A	p.G304S	Missense	10/49	-
12-133254251-T-C	POLE	c.633A>G	p.I211M	Missense	7/49	-
12-133253132-C-A	POLE	c.909G>T	p.Q303H	Missense	9/49	-
12-133253966-C-G	POLE	c.784G>C	p.D262H	Missense	8/49	-
12-133256147-G-A	POLE	c.514C>T	p.P172S	Missense	6/49	-
12-133254192-C-A	POLE	c.692G>T	p.R231L	Missense	7/49	-
12-133253142-A-T	POLE	c.899T>A	p.I300N	Missense	9/49	-
12-133253143-T-A	POLE	c.898A>T	p.I300F	Missense	9/49	-
12-133254220-G-T	POLE	c.664C>A	p.R222S	Missense	7/49	-
12-133256107-T-C	POLE	c.554A>G	p.D185G	Missense	6/49	-
12-133254171-A-T	POLE	c.713T>A	p.I238N	Missense	7/49	-
12-133256131-T-C	POLE	c.530A>G	p.N177S	Missense	6/49	-
12-133256110-C-A	POLE	c.551G>T	p.S184I	Missense	6/49	-
12-133254211-C-G	POLE	c.673G>C	p.D225H	Missense	7/49	-
12-133253156-C-G	POLE	c.885G>C	p.M295I	Missense	9/49	-
12-133253156-C-A	POLE	c.885G>T	p.M295I	Missense	9/49	-
12-133256128-C-A	POLE	c.533G>T	p.R178M	Missense	6/49	-
12-133254292-C-A	POLE	c.592G>T	p.G198C	Missense	7/49	-
12-133253977-G-T	POLE	c.773C>A	p.T258N	Missense	8/49	-
12-133254004-C-G	POLE	c.746G>C	p.R249P	Missense	8/49	-
12-133253980-A-G	POLE	c.770T>C	p.I257T	Missense	8/49	-
12-133253239-C-T	POLE	c.802G>A	p.D268N	Missense	9/49	-
12-133253987-C-T	POLE	c.763G>A	p.V255I	Missense	8/49	-
12-133253201-T-A	POLE	c.840A>T	p.K280N	Missense	9/49	-
12-133254004-C-A	POLE	c.746G>T	p.R249L	Missense	8/49	-
12-133254289-C-A	POLE	c.595G>T	p.G199C	Missense	7/49	-
12-133254001-C-T	POLE	c.749G>A	p.G250E	Missense	8/49	-
12-133253993-A-G	POLE	c.757T>C	p.F253L	Missense	8/49	-
12-133253991-A-T	POLE	c.759T>A	p.F253L	Missense	8/49	-
12-133253991-A-C	POLE	c.759T>G	p.F253L	Missense	8/49	-
12-133254229-C-T	POLE	c.655G>A	p.V219M	Missense	7/49	-
12-133256141-C-G	POLE	c.520G>C	p.V174L	Missense	6/49	-
12-133256141-C-A	POLE	c.520G>T	p.V174L	Missense	6/49	-
12-133252011-G-A	POLE	c.1199C>T	p.P400L	Missense	12/49	-
12-133252753-T-A	POLE	c.947A>T	p.D316V	Missense	10/49	-
12-133252056-T-A	POLE	c.1154A>T	p.Q385L	Missense	12/49	-
12-133251988-G-A	POLE	c.1222C>T	p.L408F	Missense	12/49	-
12-133252741-A-C	POLE	c.959T>G	p.F320C	Missense	10/49	-
12-133252330-A-C	POLE	c.1097T>G	p.F366C	Missense	11/49	-
12-133252055-C-G	POLE	c.1155G>C	p.Q385H	Missense	12/49	-
12-133251990-C-T	POLE	c.1220G>A	p.C407Y	Missense	12/49	-
12-133251992-G-T	POLE	c.1218C>A	p.D406E	Missense	12/49	-
12-133252014-G-C	POLE	c.1196C>G	p.A399G	Missense	12/49	-
12-133252745-C-G	POLE	c.955G>C	p.D319H	Missense	10/49	-
12-133252032-C-A	POLE	c.1178G>T	p.S393I	Missense	12/49	-
12-133252357-G-A	POLE	c.1070C>T	p.T357I	Missense	11/49	-
12-133252091-C-G	POLE	c.1119G>C	p.E373D	Missense	12/49	-
12-133252091-C-A	POLE	c.1119G>T	p.E373D	Missense	12/49	-
12-133252382-C-G	POLE	c.1045G>C	p.E349Q	Missense	11/49	-
12-133252751-T-C	POLE	c.949A>G	p.I317V	Missense	10/49	-
12-133252387-C-G	POLE	c.1040G>C	p.W347S	Missense	11/49	-
12-133252089-G-C	POLE	c.1121C>G	p.A374G	Missense	12/49	-
12-133252354-A-T	POLE	c.1073T>A	p.I358N	Missense	11/49	-
12-133252400-G-C	POLE	c.1027C>G	p.L343V	Missense	11/49	-
12-133252029-T-C	POLE	c.1181A>G	p.Q394R	Missense	12/49	-
12-133252005-C-A	POLE	c.1205G>T	p.C402F	Missense	12/49	-
12-133252097-A-T	POLE	c.1113T>A	p.F371L	Missense	12/49	-
12-133252097-A-C	POLE	c.1113T>G	p.F371L	Missense	12/49	-
12-133252346-T-C	POLE	c.1081A>G	p.T361A	Missense	11/49	-
12-133252350-C-G	POLE	c.1077G>C	p.M359I	Missense	11/49	-
12-133252350-C-T	POLE	c.1077G>A	p.M359I	Missense	11/49	-
12-133252350-C-A	POLE	c.1077G>T	p.M359I	Missense	11/49	-
12-133250293-C-G	POLE	c.1227G>C	p.R409S	Missense	13/49	-
12-133252036-C-A	POLE	c.1174G>T	p.D392Y	Missense	12/49	-
12-133252007-C-A	POLE	c.1203G>T	p.Q401H	Missense	12/49	-
12-133250284-C-G	POLE	c.1236G>C	p.K412N	Missense	13/49	-
12-133250284-C-A	POLE	c.1236G>T	p.K412N	Missense	13/49	-
12-133252331-A-G	POLE	c.1096T>C	p.F366L	Missense	11/49	-
12-133252329-A-T	POLE	c.1098T>A	p.F366L	Missense	11/49	-
12-133252740-A-T	POLE	c.960T>A	p.F320L	Missense	10/49	-
12-133252740-A-C	POLE	c.960T>G	p.F320L	Missense	10/49	-
12-133252711-C-G	POLE	c.989G>C	p.G330A	Missense	10/49	-
12-133252065-C-G	POLE	c.1145G>C	p.S382T	Missense	12/49	-
12-133252696-A-G	POLE	c.1004T>C	p.F335S	Missense	10/49	-
12-133252729-G-A	POLE	c.971C>T	p.P324L	Missense	10/49	-
12-133252702-C-A	POLE	c.998G>T	p.C333F	Missense	10/49	-
12-133252720-T-A	POLE	c.980A>T	p.E327V	Missense	10/49	-
12-133249770-T-C	POLE	c.1453A>G	p.I485V	Missense	14/49	-
12-133249803-C-A	POLE	c.1420G>T	p.V474F	Missense	14/49	-
12-133249857-C-A	POLE	c.1366G>T	p.A456S	Missense	14/49	-
12-133249329-A-G	POLE	c.1570T>C	p.F524L	Missense	15/49	-
12-133249327-G-T	POLE	c.1572C>A	p.F524L	Missense	15/49	-
12-133249327-G-C	POLE	c.1572C>G	p.F524L	Missense	15/49	-
12-133249331-T-A	POLE	c.1568A>T	p.E523V	Missense	15/49	-
12-133250227-C-G	POLE	c.1293G>C	p.K431N	Missense	13/49	-
12-133250227-C-A	POLE	c.1293G>T	p.K431N	Missense	13/49	-
12-133249335-G-C	POLE	c.1564C>G	p.Q522E	Missense	15/49	-
12-133249344-T-G	POLE	c.1555A>C	p.K519Q	Missense	15/49	-
12-133249347-T-C	POLE	c.1552A>G	p.N518D	Missense	15/49	-
12-133249359-T-A	POLE	c.1540A>T	p.I514F	Missense	15/49	-
12-133249366-G-T	POLE	c.1533C>A	p.H511Q	Missense	15/49	-
12-133249366-G-C	POLE	c.1533C>G	p.H511Q	Missense	15/49	-
12-133249373-G-A	POLE	c.1526C>T	p.A509V	Missense	15/49	-
12-133250262-C-T	POLE	c.1258G>A	p.G420S	Missense	13/49	-
12-133249374-C-T	POLE	c.1525G>A	p.A509T	Missense	15/49	-
12-133249373-G-C	POLE	c.1526C>G	p.A509G	Missense	15/49	-
12-133249753-G-C	POLE	c.1470C>G	p.D490E	Missense	14/49	-
12-133249753-G-T	POLE	c.1470C>A	p.D490E	Missense	14/49	-
12-133249754-T-C	POLE	c.1469A>G	p.D490G	Missense	14/49	-
12-133249839-C-G	POLE	c.1384G>C	p.D462H	Missense	14/49	-
12-133249826-G-A	POLE	c.1397C>T	p.T466I	Missense	14/49	-
12-133249381-C-G	POLE	c.1518G>C	p.M506I	Missense	15/49	-
12-133249381-C-T	POLE	c.1518G>A	p.M506I	Missense	15/49	-
12-133249385-A-G	POLE	c.1514T>C	p.L505P	Missense	15/49	-
12-133249394-T-G	POLE	c.1505A>C	p.E502A	Missense	15/49	-
12-133249400-A-T	POLE	c.1499T>A	p.L500Q	Missense	15/49	-
12-133249406-C-T	POLE	c.1493G>A	p.G498D	Missense	15/49	-
12-133249412-C-T	POLE	c.1487G>A	p.G496D	Missense	15/49	-
12-133250208-C-T	POLE	c.1312G>A	p.E438K	Missense	13/49	-
12-133249414-C-G	POLE	c.1485G>C	p.K495N	Missense	15/49	-
12-133249414-C-A	POLE	c.1485G>T	p.K495N	Missense	15/49	-
12-133250179-C-G	POLE	c.1341G>C	p.M447I	Missense	13/49	-
12-133250179-C-A	POLE	c.1341G>T	p.M447I	Missense	13/49	-
12-133252329-A-C	POLE	c.1098T>G	p.F366L	Missense	11/49	-
12-133252027-C-T	POLE	c.1183G>A	p.G395R	Missense	12/49	-
12-133252027-C-G	POLE	c.1183G>C	p.G395R	Missense	12/49	-
12-133252368-C-G	POLE	c.1059G>C	p.E353D	Missense	11/49	-
12-133252368-C-A	POLE	c.1059G>T	p.E353D	Missense	11/49	-
12-133252030-G-T	POLE	c.1180C>A	p.Q394K	Missense	12/49	-
12-133252075-G-A	POLE	c.1135C>T	p.H379Y	Missense	12/49	-
12-133250276-C-A	POLE	c.1244G>T	p.S415I	Missense	13/49	-
12-133250261-C-T	POLE	c.1259G>A	p.G420D	Missense	13/49	-
12-133250277-T-C	POLE	c.1243A>G	p.S415G	Missense	13/49	-
12-133252063-T-G	POLE	c.1147A>C	p.M383L	Missense	12/49	-
12-133252063-T-A	POLE	c.1147A>T	p.M383L	Missense	12/49	-
12-133252734-G-T	POLE	c.966C>A	p.F322L	Missense	10/49	-
12-133252734-G-C	POLE	c.966C>G	p.F322L	Missense	10/49	-
12-133252742-A-G	POLE	c.958T>C	p.F320L	Missense	10/49	-
12-133244193-C-T	POLE	c.2215G>A	p.V739M	Missense	20/49	-
12-133248805-T-C	POLE	c.1790A>G	p.E597G	Missense	16/49	-
12-133248803-C-G	POLE	c.1792G>C	p.E598Q	Missense	16/49	-
12-133245518-T-A	POLE	c.1802A>T	p.D601V	Missense	17/49	-
12-133245515-T-C	POLE	c.1805A>G	p.E602G	Missense	17/49	-
12-133248824-C-T	POLE	c.1771G>A	p.E591K	Missense	16/49	-
12-133248820-T-C	POLE	c.1775A>G	p.Q592R	Missense	16/49	-
12-133249266-C-G	POLE	c.1633G>C	p.E545Q	Missense	15/49	-
12-133249283-T-C	POLE	c.1616A>G	p.Y539C	Missense	15/49	-
12-133245521-C-G	POLE	c.1799G>C	p.C600S	Missense	17/49	-
12-133245514-C-G	POLE	c.1806G>C	p.E602D	Missense	17/49	-
12-133245514-C-A	POLE	c.1806G>T	p.E602D	Missense	17/49	-
12-133248874-A-T	POLE	c.1721T>A	p.V574D	Missense	16/49	-
12-133245515-T-G	POLE	c.1805A>C	p.E602A	Missense	17/49	-
12-133245524-A-G	POLE	c.1796T>C	p.V599A	Missense	17/49	-
12-133249281-C-A	POLE	c.1618G>T	p.V540F	Missense	15/49	-
12-133249322-T-C	POLE	c.1577A>G	p.K526R	Missense	15/49	-
12-133249235-T-A	POLE	c.1664A>T	p.D555V	Missense	15/49	-
12-133245516-C-G	POLE	c.1804G>C	p.E602Q	Missense	17/49	-
12-133245512-A-G	POLE	c.1808T>C	p.I603T	Missense	17/49	-
12-133249213-C-G	POLE	c.1686G>C	p.M562I	Missense	15/49	-
12-133249213-C-T	POLE	c.1686G>A	p.M562I	Missense	15/49	-
12-133249213-C-A	POLE	c.1686G>T	p.M562I	Missense	15/49	-
12-133245458-A-G	POLE	c.1862T>C	p.L621P	Missense	17/49	-
12-133249247-A-G	POLE	c.1652T>C	p.V551A	Missense	15/49	-
12-133249230-G-T	POLE	c.1669C>A	p.P557T	Missense	15/49	-
12-133245454-G-C	POLE	c.1866C>G	p.I622M	Missense	17/49	-
12-133249241-C-A	POLE	c.1658G>T	p.R553L	Missense	15/49	-
12-133245495-A-G	POLE	c.1825T>C	p.S609P	Missense	17/49	-
12-133245444-C-A	POLE	c.1876G>T	p.D626Y	Missense	17/49	-
12-133248830-G-T	POLE	c.1765C>A	p.P589T	Missense	16/49	-
12-133248896-A-G	POLE	c.1699T>C	p.F567L	Missense	16/49	-
12-133248894-A-T	POLE	c.1701T>A	p.F567L	Missense	16/49	-
12-133248894-A-C	POLE	c.1701T>G	p.F567L	Missense	16/49	-
12-133248889-A-C	POLE	c.1706T>G	p.F569C	Missense	16/49	-
12-133248893-C-A	POLE	c.1702G>T	p.D568Y	Missense	16/49	-
12-133248880-T-C	POLE	c.1715A>G	p.Q572R	Missense	16/49	-
12-133248893-C-G	POLE	c.1702G>C	p.D568H	Missense	16/49	-
12-133245470-A-T	POLE	c.1850T>A	p.I617N	Missense	17/49	-
12-133245443-T-C	POLE	c.1877A>G	p.D626G	Missense	17/49	-
12-133249290-C-T	POLE	c.1609G>A	p.E537K	Missense	15/49	-
12-133249292-G-A	POLE	c.1607C>T	p.S536F	Missense	15/49	-
12-133249229-G-C	POLE	c.1670C>G	p.P557R	Missense	15/49	-
12-133248869-T-G	POLE	c.1726A>C	p.K576Q	Missense	16/49	-
12-133248889-A-G	POLE	c.1706T>C	p.F569S	Missense	16/49	-
12-133248842-C-T	POLE	c.1753G>A	p.E585K	Missense	16/49	-
12-133245456-T-C	POLE	c.1864A>G	p.I622V	Missense	17/49	-
12-133249290-C-G	POLE	c.1609G>C	p.E537Q	Missense	15/49	-
12-133245435-C-A	POLE	c.1885G>T	p.A629S	Missense	17/49	-
12-133249239-T-C	POLE	c.1660A>G	p.S554G	Missense	15/49	-
12-133245437-C-T	POLE	c.1883G>A	p.G628E	Missense	17/49	-
12-133245494-G-A	POLE	c.1826C>T	p.S609F	Missense	17/49	-
12-133249226-C-T	POLE	c.1673G>A	p.C558Y	Missense	15/49	-
12-133248856-T-C	POLE	c.1739A>G	p.H580R	Missense	16/49	-
12-133244971-T-C	POLE	c.2144A>G	p.Q715R	Missense	19/49	-
12-133245049-T-A	POLE	c.2066A>T	p.Q689L	Missense	19/49	-
12-133244216-T-A	POLE	c.2192A>T	p.Y731F	Missense	20/49	-
12-133245272-G-A	POLE	c.1975C>T	p.P659S	Missense	18/49	-
12-133244231-T-A	POLE	c.2177A>T	p.Y726F	Missense	20/49	-
12-133244222-T-A	POLE	c.2186A>T	p.K729I	Missense	20/49	-
12-133245274-T-G	POLE	c.1973A>C	p.K658T	Missense	18/49	-
12-133245271-G-C	POLE	c.1976C>G	p.P659R	Missense	18/49	-
12-133245038-C-G	POLE	c.2077G>C	p.E693Q	Missense	19/49	-
12-133244993-G-A	POLE	c.2122C>T	p.H708Y	Missense	19/49	-
12-133245016-G-T	POLE	c.2099C>A	p.P700Q	Missense	19/49	-
12-133245087-C-G	POLE	c.2028G>C	p.M676I	Missense	19/49	-
12-133245087-C-T	POLE	c.2028G>A	p.M676I	Missense	19/49	-
12-133245226-T-G	POLE	c.2021A>C	p.E674A	Missense	18/49	-
12-133245061-C-A	POLE	c.2054G>T	p.R685L	Missense	19/49	-
12-133244225-C-G	POLE	c.2183G>C	p.R728P	Missense	20/49	-
12-133244942-C-G	POLE	c.2173G>C	p.D725H	Missense	19/49	-
12-133245017-G-C	POLE	c.2098C>G	p.P700A	Missense	19/49	-
12-133244231-T-G	POLE	c.2177A>C	p.Y726S	Missense	20/49	-
12-133244948-G-C	POLE	c.2167C>G	p.L723V	Missense	19/49	-
12-133245221-T-G	POLE	c.2026A>C	p.M676L	Missense	18/49	-
12-133245221-T-A	POLE	c.2026A>T	p.M676L	Missense	18/49	-
12-133245061-C-G	POLE	c.2054G>C	p.R685P	Missense	19/49	-
12-133245301-G-A	POLE	c.1946C>T	p.A649V	Missense	18/49	-
12-133245031-A-G	POLE	c.2084T>C	p.F695S	Missense	19/49	-
12-133244213-T-C	POLE	c.2195A>G	p.K732R	Missense	20/49	-
12-133245401-A-T	POLE	c.1919T>A	p.L640Q	Missense	17/49	-
12-133245319-G-A	POLE	c.1928C>T	p.S643F	Missense	18/49	-
12-133244171-A-G	POLE	c.2237T>C	p.I746T	Missense	20/49	-
12-133244205-G-A	POLE	c.2203C>T	p.H735Y	Missense	20/49	-
12-133245245-C-T	POLE	c.2002G>A	p.A668T	Missense	18/49	-
12-133245248-T-A	POLE	c.1999A>T	p.M667L	Missense	18/49	-
12-133244175-T-C	POLE	c.2233A>G	p.T745A	Missense	20/49	-
12-133245231-C-G	POLE	c.2016G>C	p.R672S	Missense	18/49	-
12-133245230-C-T	POLE	c.2017G>A	p.G673S	Missense	18/49	-
12-133245005-C-A	POLE	c.2110G>T	p.A704S	Missense	19/49	-
12-133245397-C-A	POLE	c.1923G>T	p.Q641H	Missense	17/49	-
12-133245397-C-G	POLE	c.1923G>C	p.Q641H	Missense	17/49	-
12-133245435-C-T	POLE	c.1885G>A	p.A629T	Missense	17/49	-
12-133245410-G-A	POLE	c.1910C>T	p.T637I	Missense	17/49	-
12-133245241-C-A	POLE	c.2006G>T	p.W669L	Missense	18/49	-
12-133245011-C-A	POLE	c.2104G>T	p.G702W	Missense	19/49	-
12-133244181-G-C	POLE	c.2227C>G	p.L743V	Missense	20/49	-
12-133242009-C-A	POLE	c.2347G>T	p.V783L	Missense	21/49	-
12-133242009-C-G	POLE	c.2347G>C	p.V783L	Missense	21/49	-
12-133240678-G-A	POLE	c.2618C>T	p.P873L	Missense	23/49	-
12-133241975-C-T	POLE	c.2381G>A	p.C794Y	Missense	21/49	-
12-133241937-C-A	POLE	c.2419G>T	p.A807S	Missense	21/49	-
12-133244168-C-A	POLE	c.2240G>T	p.C747F	Missense	20/49	-
12-133241967-T-C	POLE	c.2389A>G	p.M797V	Missense	21/49	-
12-133240956-C-A	POLE	c.2561G>T	p.G854V	Missense	22/49	-
12-133240714-G-A	POLE	c.2582C>T	p.T861I	Missense	23/49	-
12-133241961-C-T	POLE	c.2395G>A	p.V799M	Missense	21/49	-
12-133241986-C-G	POLE	c.2370G>C	p.E790D	Missense	21/49	-
12-133241986-C-A	POLE	c.2370G>T	p.E790D	Missense	21/49	-
12-133240684-C-T	POLE	c.2612G>A	p.S871N	Missense	23/49	-
12-133240685-T-A	POLE	c.2611A>T	p.S871C	Missense	23/49	-
12-133241988-C-G	POLE	c.2368G>C	p.E790Q	Missense	21/49	-
12-133240724-C-T	POLE	c.2572G>A	p.E858K	Missense	23/49	-
12-133241909-T-C	POLE	c.2447A>G	p.Y816C	Missense	21/49	-
12-133244100-C-T	POLE	c.2308G>A	p.G770R	Missense	20/49	-
12-133241964-C-T	POLE	c.2392G>A	p.E798K	Missense	21/49	-
12-133241029-C-T	POLE	c.2488G>A	p.E830K	Missense	22/49	-
12-133242003-C-G	POLE	c.2353G>C	p.V785L	Missense	21/49	-
12-133242003-C-A	POLE	c.2353G>T	p.V785L	Missense	21/49	-
12-133242004-C-G	POLE	c.2352G>C	p.E784D	Missense	21/49	-
12-133242004-C-A	POLE	c.2352G>T	p.E784D	Missense	21/49	-
12-133241034-G-A	POLE	c.2483C>T	p.S828F	Missense	22/49	-
12-133244106-A-C	POLE	c.2302T>G	p.F768V	Missense	20/49	-
12-133241991-C-A	POLE	c.2365G>T	p.A789S	Missense	21/49	-
12-133241016-A-G	POLE	c.2501T>C	p.I834T	Missense	22/49	-
12-133241037-T-C	POLE	c.2480A>G	p.Y827C	Missense	22/49	-
12-133240733-T-A	POLE	c.2563A>T	p.R855W	Missense	23/49	-
12-133242035-A-C	POLE	c.2321T>G	p.V774G	Missense	21/49	-
12-133241962-C-G	POLE	c.2394G>C	p.E798D	Missense	21/49	-
12-133241962-C-A	POLE	c.2394G>T	p.E798D	Missense	21/49	-
12-133240998-G-C	POLE	c.2519C>G	p.A840G	Missense	22/49	-
12-133240697-C-G	POLE	c.2599G>C	p.V867L	Missense	23/49	-
12-133241928-A-C	POLE	c.2428T>G	p.C810G	Missense	21/49	-
12-133240711-T-C	POLE	c.2585A>G	p.D862G	Missense	23/49	-
12-133244115-G-A	POLE	c.2293C>T	p.R765C	Missense	20/49	-
12-133240973-C-A	POLE	c.2544G>T	p.E848D	Missense	22/49	-
12-133241039-C-G	POLE	c.2478G>C	p.W826C	Missense	22/49	-
12-133241904-A-G	POLE	c.2452T>C	p.Y818H	Missense	21/49	-
12-133240980-G-T	POLE	c.2537C>A	p.A846E	Missense	22/49	-
12-133244147-T-C	POLE	c.2261A>G	p.Y754C	Missense	20/49	-
12-133240982-C-A	POLE	c.2535G>T	p.Q845H	Missense	22/49	-
12-133240982-C-G	POLE	c.2535G>C	p.Q845H	Missense	22/49	-
12-133240999-C-T	POLE	c.2518G>A	p.A840T	Missense	22/49	-
12-133244165-T-A	POLE	c.2243A>T	p.Q748L	Missense	20/49	-
12-133244135-A-C	POLE	c.2273T>G	p.V758G	Missense	20/49	-
12-133238245-T-G	POLE	c.2732A>C	p.Q911P	Missense	24/49	-
12-133238243-C-T	POLE	c.2734G>A	p.E912K	Missense	24/49	-
12-133237683-C-T	POLE	c.2932G>A	p.E978K	Missense	25/49	-
12-133236080-C-G	POLE	c.3076G>C	p.D1026H	Missense	26/49	-
12-133237650-C-G	POLE	c.2965G>C	p.V989L	Missense	25/49	-
12-133237650-C-A	POLE	c.2965G>T	p.V989L	Missense	25/49	-
12-133238237-C-G	POLE	c.2740G>C	p.A914P	Missense	24/49	-
12-133237731-C-T	POLE	c.2884G>A	p.D962N	Missense	25/49	-
12-133238268-T-G	POLE	c.2709A>C	p.E903D	Missense	24/49	-
12-133238268-T-A	POLE	c.2709A>T	p.E903D	Missense	24/49	-
12-133237730-T-C	POLE	c.2885A>G	p.D962G	Missense	25/49	-
12-133238135-C-T	POLE	c.2842G>A	p.E948K	Missense	24/49	-
12-133237691-C-A	POLE	c.2924G>T	p.R975L	Missense	25/49	-
12-133236086-T-C	POLE	c.3070A>G	p.M1024V	Missense	26/49	-
12-133240676-C-T	POLE	c.2620G>A	p.E874K	Missense	23/49	-
12-133238251-T-C	POLE	c.2726A>G	p.Q909R	Missense	24/49	-
12-133240639-G-T	POLE	c.2657C>A	p.P886H	Missense	23/49	-
12-133236084-C-G	POLE	c.3072G>C	p.M1024I	Missense	26/49	-
12-133236084-C-T	POLE	c.3072G>A	p.M1024I	Missense	26/49	-
12-133238149-G-A	POLE	c.2828C>T	p.P943L	Missense	24/49	-
12-133236095-C-A	POLE	c.3061G>T	p.A1021S	Missense	26/49	-
12-133238135-C-G	POLE	c.2842G>C	p.E948Q	Missense	24/49	-
12-133237719-C-A	POLE	c.2896G>T	p.A966S	Missense	25/49	-
12-133237728-C-A	POLE	c.2887G>T	p.G963C	Missense	25/49	-
12-133240603-T-C	POLE	c.2693A>G	p.N898S	Missense	23/49	-
12-133237719-C-G	POLE	c.2896G>C	p.A966P	Missense	25/49	-
12-133238270-C-T	POLE	c.2707G>A	p.E903K	Missense	24/49	-
12-133238177-C-G	POLE	c.2800G>C	p.D934H	Missense	24/49	-
12-133238180-C-T	POLE	c.2797G>A	p.V933I	Missense	24/49	-
12-133236094-G-C	POLE	c.3062C>G	p.A1021G	Missense	26/49	-
12-133238171-G-A	POLE	c.2806C>T	p.P936S	Missense	24/49	-
12-133238165-G-A	POLE	c.2812C>T	p.L938F	Missense	24/49	-
12-133238188-A-C	POLE	c.2789T>G	p.F930C	Missense	24/49	-
12-133238192-T-C	POLE	c.2785A>G	p.I929V	Missense	24/49	-
12-133236094-G-T	POLE	c.3062C>A	p.A1021E	Missense	26/49	-
12-133237556-T-C	POLE	c.3059A>G	p.K1020R	Missense	25/49	-
12-133238176-T-A	POLE	c.2801A>T	p.D934V	Missense	24/49	-
12-133237559-C-A	POLE	c.3056G>T	p.S1019I	Missense	25/49	-
12-133237560-T-A	POLE	c.3055A>T	p.S1019C	Missense	25/49	-
12-133237563-A-G	POLE	c.3052T>C	p.Y1018H	Missense	25/49	-
12-133237562-T-C	POLE	c.3053A>G	p.Y1018C	Missense	25/49	-
12-133238207-G-C	POLE	c.2770C>G	p.R924G	Missense	24/49	-
12-133237584-C-A	POLE	c.3031G>T	p.D1011Y	Missense	25/49	-
12-133237611-C-T	POLE	c.3004G>A	p.V1002M	Missense	25/49	-
12-133240659-C-A	POLE	c.2637G>T	p.K879N	Missense	23/49	-
12-133240657-G-T	POLE	c.2639C>A	p.T880K	Missense	23/49	-
12-133238221-A-G	POLE	c.2756T>C	p.L919P	Missense	24/49	-
12-133240654-G-A	POLE	c.2642C>T	p.T881I	Missense	23/49	-
12-133240661-T-G	POLE	c.2635A>C	p.K879Q	Missense	23/49	-
12-133238201-C-G	POLE	c.2776G>C	p.E926Q	Missense	24/49	-
12-133238165-G-C	POLE	c.2812C>G	p.L938V	Missense	24/49	-
12-133234004-C-G	POLE	c.3390G>C	p.W1130C	Missense	28/49	-
12-133233991-C-T	POLE	c.3403G>A	p.E1135K	Missense	28/49	-
12-133233965-C-G	POLE	c.3429G>C	p.K1143N	Missense	28/49	-
12-133233965-C-A	POLE	c.3429G>T	p.K1143N	Missense	28/49	-
12-133233989-C-G	POLE	c.3405G>C	p.E1135D	Missense	28/49	-
12-133233989-C-A	POLE	c.3405G>T	p.E1135D	Missense	28/49	-
12-133233994-T-A	POLE	c.3400A>T	p.I1134F	Missense	28/49	-
12-133233997-A-G	POLE	c.3397T>C	p.Y1133H	Missense	28/49	-
12-133233996-T-C	POLE	c.3398A>G	p.Y1133C	Missense	28/49	-
12-133234014-A-G	POLE	c.3380T>C	p.I1127T	Missense	28/49	-
12-133235958-G-C	POLE	c.3198C>G	p.D1066E	Missense	26/49	-
12-133235958-G-T	POLE	c.3198C>A	p.D1066E	Missense	26/49	-
12-133234002-T-C	POLE	c.3392A>G	p.D1131G	Missense	28/49	-
12-133235962-C-T	POLE	c.3194G>A	p.G1065E	Missense	26/49	-
12-133235969-A-G	POLE	c.3187T>C	p.F1063L	Missense	26/49	-
12-133235967-G-T	POLE	c.3189C>A	p.F1063L	Missense	26/49	-
12-133235967-G-C	POLE	c.3189C>G	p.F1063L	Missense	26/49	-
12-133235945-C-G	POLE	c.3211G>C	p.D1071H	Missense	26/49	-
12-133235996-T-C	POLE	c.3160A>G	p.I1054V	Missense	26/49	-
12-133235941-G-C	POLE	c.3215C>G	p.A1072G	Missense	26/49	-
12-133236044-A-C	POLE	c.3112T>G	p.S1038A	Missense	26/49	-
12-133236009-C-G	POLE	c.3147G>C	p.Q1049H	Missense	26/49	-
12-133236031-T-C	POLE	c.3125A>G	p.K1042R	Missense	26/49	-
12-133234492-G-A	POLE	c.3340C>T	p.L1114F	Missense	27/49	-
12-133235926-C-A	POLE	c.3230G>T	p.R1077L	Missense	26/49	-
12-133234554-G-A	POLE	c.3278C>T	p.A1093V	Missense	27/49	-
12-133234479-G-A	POLE	c.3353C>T	p.S1118F	Missense	27/49	-
12-133234480-A-C	POLE	c.3352T>G	p.S1118A	Missense	27/49	-
12-133235901-C-G	POLE	c.3255G>C	p.E1085D	Missense	26/49	-
12-133235901-C-A	POLE	c.3255G>T	p.E1085D	Missense	26/49	-
12-133236077-A-C	POLE	c.3079T>G	p.S1027A	Missense	26/49	-
12-133236063-C-G	POLE	c.3093G>C	p.E1031D	Missense	26/49	-
12-133236063-C-A	POLE	c.3093G>T	p.E1031D	Missense	26/49	-
12-133234484-G-C	POLE	c.3348C>G	p.S1116R	Missense	27/49	-
12-133234484-G-T	POLE	c.3348C>A	p.S1116R	Missense	27/49	-
12-133234486-T-G	POLE	c.3346A>C	p.S1116R	Missense	27/49	-
12-133234487-C-G	POLE	c.3345G>C	p.K1115N	Missense	27/49	-
12-133235923-T-A	POLE	c.3233A>T	p.Y1078F	Missense	26/49	-
12-133234556-C-G	POLE	c.3276G>C	p.R1092S	Missense	27/49	-
12-133234556-C-A	POLE	c.3276G>T	p.R1092S	Missense	27/49	-
12-133234506-A-C	POLE	c.3326T>G	p.F1109C	Missense	27/49	-
12-133234489-T-C	POLE	c.3343A>G	p.K1115E	Missense	27/49	-
12-133235887-G-C	POLE	c.3269C>G	p.T1090R	Missense	26/49	-
12-133233790-G-C	POLE	c.3514C>G	p.L1172V	Missense	29/49	-
12-133234470-T-C	POLE	c.3362A>G	p.D1121G	Missense	27/49	-
12-133236068-A-G	POLE	c.3088T>C	p.F1030L	Missense	26/49	-
12-133236066-G-C	POLE	c.3090C>G	p.F1030L	Missense	26/49	-
12-133233835-G-A	POLE	c.3469C>T	p.P1157S	Missense	29/49	-
12-133234511-C-G	POLE	c.3321G>C	p.K1107N	Missense	27/49	-
12-133234511-C-A	POLE	c.3321G>T	p.K1107N	Missense	27/49	-
12-133234519-C-G	POLE	c.3313G>C	p.V1105L	Missense	27/49	-
12-133234519-C-A	POLE	c.3313G>T	p.V1105L	Missense	27/49	-
12-133234519-C-T	POLE	c.3313G>A	p.V1105M	Missense	27/49	-
12-133234546-G-C	POLE	c.3286C>G	p.L1096V	Missense	27/49	-
12-133233955-T-C	POLE	c.3439A>G	p.I1147V	Missense	28/49	-
12-133234462-T-A	POLE	c.3370A>T	p.I1124F	Missense	27/49	-
12-133226446-A-T	POLE	c.3612T>A	p.S1204R	Missense	30/49	-
12-133226434-A-C	POLE	c.3624T>G	p.S1208R	Missense	30/49	-
12-133226434-A-T	POLE	c.3624T>A	p.S1208R	Missense	30/49	-
12-133226351-C-A	POLE	c.3707G>T	p.W1236L	Missense	30/49	-
12-133226292-C-A	POLE	c.3766G>T	p.G1256W	Missense	30/49	-
12-133226403-T-G	POLE	c.3655A>C	p.K1219Q	Missense	30/49	-
12-133226298-T-C	POLE	c.3760A>G	p.I1254V	Missense	30/49	-
12-133226448-T-G	POLE	c.3610A>C	p.S1204R	Missense	30/49	-
12-133226316-T-G	POLE	c.3742A>C	p.T1248P	Missense	30/49	-
12-133233777-T-A	POLE	c.3527A>T	p.D1176V	Missense	29/49	-
12-133226077-A-G	POLE	c.3820T>C	p.F1274L	Missense	31/49	-
12-133226075-G-T	POLE	c.3822C>A	p.F1274L	Missense	31/49	-
12-133226075-G-C	POLE	c.3822C>G	p.F1274L	Missense	31/49	-
12-133226011-C-G	POLE	c.3886G>C	p.E1296Q	Missense	31/49	-
12-133226341-C-A	POLE	c.3717G>T	p.Q1239H	Missense	30/49	-
12-133226341-C-G	POLE	c.3717G>C	p.Q1239H	Missense	30/49	-
12-133226035-C-G	POLE	c.3862G>C	p.A1288P	Missense	31/49	-
12-133226052-T-A	POLE	c.3845A>T	p.Q1282L	Missense	31/49	-
12-133226024-C-G	POLE	c.3873G>C	p.K1291N	Missense	31/49	-
12-133226423-A-C	POLE	c.3635T>G	p.M1212R	Missense	30/49	-
12-133226412-C-A	POLE	c.3646G>T	p.G1216C	Missense	30/49	-
12-133233764-C-A	POLE	c.3540G>T	p.Q1180H	Missense	29/49	-
12-133233764-C-G	POLE	c.3540G>C	p.Q1180H	Missense	29/49	-
12-133233728-C-G	POLE	c.3576G>C	p.R1192S	Missense	29/49	-
12-133233728-C-A	POLE	c.3576G>T	p.R1192S	Missense	29/49	-
12-133233730-T-C	POLE	c.3574A>G	p.R1192G	Missense	29/49	-
12-133226058-T-A	POLE	c.3839A>T	p.Q1280L	Missense	31/49	-
12-133226474-A-T	POLE	c.3584T>A	p.V1195D	Missense	30/49	-
12-133226347-C-G	POLE	c.3711G>C	p.E1237D	Missense	30/49	-
12-133226347-C-A	POLE	c.3711G>T	p.E1237D	Missense	30/49	-
12-133226475-C-T	POLE	c.3583G>A	p.V1195I	Missense	30/49	-
12-133226475-C-A	POLE	c.3583G>T	p.V1195F	Missense	30/49	-
12-133226337-C-G	POLE	c.3721G>C	p.E1241Q	Missense	30/49	-
12-133233735-T-C	POLE	c.3569A>G	p.E1190G	Missense	29/49	-
12-133226334-A-T	POLE	c.3724T>A	p.S1242T	Missense	30/49	-
12-133226451-C-A	POLE	c.3607G>T	p.D1203Y	Missense	30/49	-
12-133226376-T-C	POLE	c.3682A>G	p.T1228A	Missense	30/49	-
12-133226061-C-A	POLE	c.3836G>T	p.W1279L	Missense	31/49	-
12-133226382-G-C	POLE	c.3676C>G	p.P1226A	Missense	30/49	-
12-133226345-C-G	POLE	c.3713G>C	p.S1238T	Missense	30/49	-
12-133226379-C-A	POLE	c.3679G>T	p.V1227F	Missense	30/49	-
12-133226411-C-T	POLE	c.3647G>A	p.G1216D	Missense	30/49	-
12-133226328-C-A	POLE	c.3730G>T	p.D1244Y	Missense	30/49	-
12-133226047-G-C	POLE	c.3850C>G	p.R1284G	Missense	31/49	-
12-133233736-C-G	POLE	c.3568G>C	p.E1190Q	Missense	29/49	-
12-133233723-T-C	POLE	c.3581A>G	p.Q1194R	Missense	29/49	-
12-133226340-C-G	POLE	c.3718G>C	p.E1240Q	Missense	30/49	-
12-133233768-T-C	POLE	c.3536A>G	p.K1179R	Missense	29/49	-
12-133233726-C-T	POLE	c.3578G>A	p.R1193K	Missense	29/49	-
12-133226375-G-C	POLE	c.3683C>G	p.T1228S	Missense	30/49	-
12-133226376-T-A	POLE	c.3682A>T	p.T1228S	Missense	30/49	-
12-133233726-C-A	POLE	c.3578G>T	p.R1193I	Missense	29/49	-
12-133226427-C-T	POLE	c.3631G>A	p.D1211N	Missense	30/49	-
12-133233727-T-C	POLE	c.3577A>G	p.R1193G	Missense	29/49	-
12-133226438-G-C	POLE	c.3620C>G	p.P1207R	Missense	30/49	-
12-133226451-C-T	POLE	c.3607G>A	p.D1203N	Missense	30/49	-
12-133233754-T-C	POLE	c.3550A>G	p.S1184G	Missense	29/49	-
12-133226418-C-A	POLE	c.3640G>T	p.D1214Y	Missense	30/49	-
12-133226288-T-G	POLE	c.3770A>C	p.Q1257P	Missense	30/49	-
12-133226288-T-A	POLE	c.3770A>T	p.Q1257L	Missense	30/49	-
12-133226273-C-T	POLE	c.3785G>A	p.G1262E	Missense	30/49	-
12-133225573-C-A	POLE	c.4091G>T	p.R1364L	Missense	32/49	-
12-133225568-A-G	POLE	c.4096T>C	p.F1366L	Missense	32/49	-
12-133225566-G-T	POLE	c.4098C>A	p.F1366L	Missense	32/49	-
12-133225566-G-C	POLE	c.4098C>G	p.F1366L	Missense	32/49	-
12-133225565-A-C	POLE	c.4099T>G	p.Y1367D	Missense	32/49	-
12-133225565-A-G	POLE	c.4099T>C	p.Y1367H	Missense	32/49	-
12-133225951-C-A	POLE	c.3946G>T	p.G1316W	Missense	31/49	-
12-133225555-T-C	POLE	c.4109A>G	p.Q1370R	Missense	32/49	-
12-133225932-G-T	POLE	c.3965C>A	p.T1322N	Missense	31/49	-
12-133225909-G-A	POLE	c.3988C>T	p.P1330S	Missense	31/49	-
12-133225950-C-T	POLE	c.3947G>A	p.G1316E	Missense	31/49	-
12-133225954-G-T	POLE	c.3943C>A	p.L1315M	Missense	31/49	-
12-133225944-A-G	POLE	c.3953T>C	p.F1318S	Missense	31/49	-
12-133225546-G-A	POLE	c.4118C>T	p.A1373V	Missense	32/49	-
12-133225941-A-G	POLE	c.3956T>C	p.L1319S	Missense	31/49	-
12-133225559-T-C	POLE	c.4105A>G	p.N1369D	Missense	32/49	-
12-133225940-C-A	POLE	c.3957G>T	p.L1319F	Missense	31/49	-
12-133225940-C-G	POLE	c.3957G>C	p.L1319F	Missense	31/49	-
12-133225942-A-C	POLE	c.3955T>G	p.L1319V	Missense	31/49	-
12-133225948-T-A	POLE	c.3949A>T	p.S1317C	Missense	31/49	-
12-133225620-C-A	POLE	c.4044G>T	p.W1348C	Missense	32/49	-
12-133225620-C-G	POLE	c.4044G>C	p.W1348C	Missense	32/49	-
12-133225995-A-G	POLE	c.3902T>C	p.V1301A	Missense	31/49	-
12-133220544-C-A	POLE	c.4169G>T	p.R1390L	Missense	33/49	-
12-133225582-C-T	POLE	c.4082G>A	p.S1361N	Missense	32/49	-
12-133225536-C-G	POLE	c.4128G>C	p.E1376D	Missense	32/49	-
12-133225536-C-A	POLE	c.4128G>T	p.E1376D	Missense	32/49	-
12-133225591-A-G	POLE	c.4073T>C	p.I1358T	Missense	32/49	-
12-133225605-A-T	POLE	c.4059T>A	p.S1353R	Missense	32/49	-
12-133225607-T-G	POLE	c.4057A>C	p.S1353R	Missense	32/49	-
12-133225899-A-G	POLE	c.3998T>C	p.I1333T	Missense	31/49	-
12-133225582-C-A	POLE	c.4082G>T	p.S1361I	Missense	32/49	-
12-133225583-T-C	POLE	c.4081A>G	p.S1361G	Missense	32/49	-
12-133225537-T-C	POLE	c.4127A>G	p.E1376G	Missense	32/49	-
12-133225945-A-G	POLE	c.3952T>C	p.F1318L	Missense	31/49	-
12-133225943-G-T	POLE	c.3954C>A	p.F1318L	Missense	31/49	-
12-133225943-G-C	POLE	c.3954C>G	p.F1318L	Missense	31/49	-
12-133225585-A-T	POLE	c.4079T>A	p.L1360Q	Missense	32/49	-
12-133225641-C-A	POLE	c.4023G>T	p.Q1341H	Missense	32/49	-
12-133225641-C-G	POLE	c.4023G>C	p.Q1341H	Missense	32/49	-
12-133225602-G-C	POLE	c.4062C>G	p.D1354E	Missense	32/49	-
12-133225522-T-A	POLE	c.4142A>T	p.Y1381F	Missense	32/49	-
12-133225993-G-T	POLE	c.3904C>A	p.L1302I	Missense	31/49	-
12-133225520-G-T	POLE	c.4144C>A	p.R1382S	Missense	32/49	-
12-133225978-T-A	POLE	c.3919A>T	p.I1307F	Missense	31/49	-
12-133225640-C-A	POLE	c.4024G>T	p.A1342S	Missense	32/49	-
12-133225905-C-A	POLE	c.3992G>T	p.W1331L	Missense	31/49	-
12-133225631-A-G	POLE	c.4033T>C	p.F1345L	Missense	32/49	-
12-133225629-G-T	POLE	c.4035C>A	p.F1345L	Missense	32/49	-
12-133225629-G-C	POLE	c.4035C>G	p.F1345L	Missense	32/49	-
12-133225627-C-T	POLE	c.4037G>A	p.R1346K	Missense	32/49	-
12-133220501-C-G	POLE	c.4212G>C	p.E1404D	Missense	33/49	-
12-133220501-C-A	POLE	c.4212G>T	p.E1404D	Missense	33/49	-
12-133219854-A-G	POLE	c.4507T>C	p.F1503L	Missense	35/49	-
12-133219852-G-T	POLE	c.4509C>A	p.F1503L	Missense	35/49	-
12-133219852-G-C	POLE	c.4509C>G	p.F1503L	Missense	35/49	-
12-133219834-C-G	POLE	c.4527G>C	p.R1509S	Missense	35/49	-
12-133219834-C-A	POLE	c.4527G>T	p.R1509S	Missense	35/49	-
12-133220022-G-T	POLE	c.4415C>A	p.S1472Y	Missense	34/49	-
12-133219851-T-C	POLE	c.4510A>G	p.I1504V	Missense	35/49	-
12-133219857-T-C	POLE	c.4504A>G	p.I1502V	Missense	35/49	-
12-133220113-C-T	POLE	c.4324G>A	p.G1442S	Missense	34/49	-
12-133219856-A-T	POLE	c.4505T>A	p.I1502N	Missense	35/49	-
12-133219890-G-T	POLE	c.4471C>A	p.H1491N	Missense	35/49	-
12-133219853-A-C	POLE	c.4508T>G	p.F1503C	Missense	35/49	-
12-133219841-T-C	POLE	c.4520A>G	p.Q1507R	Missense	35/49	-
12-133219877-G-A	POLE	c.4484C>T	p.A1495V	Missense	35/49	-
12-133219873-G-T	POLE	c.4488C>A	p.H1496Q	Missense	35/49	-
12-133219873-G-C	POLE	c.4488C>G	p.H1496Q	Missense	35/49	-
12-133220424-T-G	POLE	c.4289A>C	p.Q1430P	Missense	33/49	-
12-133220046-G-A	POLE	c.4391C>T	p.A1464V	Missense	34/49	-
12-133220056-C-G	POLE	c.4381G>C	p.E1461Q	Missense	34/49	-
12-133220134-A-G	POLE	c.4303T>C	p.F1435L	Missense	34/49	-
12-133240968-A-G	POLE	c.2549T>C	p.I850T	Missense	22/49	-
12-133219886-T-C	POLE	c.4475A>G	p.H1492R	Missense	35/49	-
12-133219887-G-A	POLE	c.4474C>T	p.H1492Y	Missense	35/49	-
12-133220079-C-T	POLE	c.4358G>A	p.R1453K	Missense	34/49	-
12-133220037-T-A	POLE	c.4400A>T	p.H1467L	Missense	34/49	-
12-133219860-C-G	POLE	c.4501G>C	p.G1501R	Missense	35/49	-
12-133219872-T-C	POLE	c.4489A>G	p.K1497E	Missense	35/49	-
12-133219901-A-C	POLE	c.4460T>G	p.I1487S	Missense	35/49	-
12-133220106-A-T	POLE	c.4331T>A	p.V1444E	Missense	34/49	-
12-133220023-A-T	POLE	c.4414T>A	p.S1472T	Missense	34/49	-
12-133220464-C-G	POLE	c.4249G>C	p.E1417Q	Missense	33/49	-
12-133220482-T-G	POLE	c.4231A>C	p.I1411L	Missense	33/49	-
12-133220455-C-A	POLE	c.4258G>T	p.A1420S	Missense	33/49	-
12-133220452-G-T	POLE	c.4261C>A	p.P1421T	Missense	33/49	-
12-133220025-C-A	POLE	c.4412G>T	p.R1471L	Missense	34/49	-
12-133220479-T-A	POLE	c.4234A>T	p.N1412Y	Missense	33/49	-
12-133220431-C-G	POLE	c.4282G>C	p.E1428Q	Missense	33/49	-
12-133220530-A-G	POLE	c.4183T>C	p.Y1395H	Missense	33/49	-
12-133220437-C-G	POLE	c.4276G>C	p.V1426L	Missense	33/49	-
12-133220440-C-A	POLE	c.4273G>T	p.G1425C	Missense	33/49	-
12-133220523-A-C	POLE	c.4190T>G	p.L1397R	Missense	33/49	-
12-133220541-G-A	POLE	c.4172C>T	p.S1391F	Missense	33/49	-
12-133220098-C-A	POLE	c.4339G>T	p.V1447F	Missense	34/49	-
12-133220087-C-A	POLE	c.4350G>T	p.Q1450H	Missense	34/49	-
12-133220087-C-G	POLE	c.4350G>C	p.Q1450H	Missense	34/49	-
12-133220077-G-T	POLE	c.4360C>A	p.H1454N	Missense	34/49	-
12-133220107-C-T	POLE	c.4330G>A	p.V1444M	Missense	34/49	-
12-133220078-C-G	POLE	c.4359G>C	p.R1453S	Missense	34/49	-
12-133220078-C-A	POLE	c.4359G>T	p.R1453S	Missense	34/49	-
12-133219914-T-C	POLE	c.4447A>G	p.S1483G	Missense	35/49	-
12-133220038-G-A	POLE	c.4399C>T	p.H1467Y	Missense	34/49	-
12-133220035-G-C	POLE	c.4402C>G	p.L1468V	Missense	34/49	-
12-133220534-C-G	POLE	c.4179G>C	p.M1393I	Missense	33/49	-
12-133220534-C-T	POLE	c.4179G>A	p.M1393I	Missense	33/49	-
12-133219119-C-A	POLE	c.4925G>T	p.C1642F	Missense	37/49	-
12-133219251-C-T	POLE	c.4793G>A	p.S1598N	Missense	37/49	-
12-133219251-C-A	POLE	c.4793G>T	p.S1598I	Missense	37/49	-
12-133219528-G-A	POLE	c.4606C>T	p.L1536F	Missense	36/49	-
12-133219435-C-T	POLE	c.4699G>A	p.A1567T	Missense	36/49	-
12-133219569-T-C	POLE	c.4565A>G	p.Q1522R	Missense	36/49	-
12-133219140-T-C	POLE	c.4904A>G	p.H1635R	Missense	37/49	-
12-133219519-C-T	POLE	c.4615G>A	p.E1539K	Missense	36/49	-
12-133219294-G-C	POLE	c.4750C>G	p.L1584V	Missense	37/49	-
12-133219293-A-C	POLE	c.4751T>G	p.L1584R	Missense	37/49	-
12-133219147-T-C	POLE	c.4897A>G	p.I1633V	Missense	37/49	-
12-133219145-G-C	POLE	c.4899C>G	p.I1633M	Missense	37/49	-
12-133219148-C-G	POLE	c.4896G>C	p.M1632I	Missense	37/49	-
12-133219148-C-A	POLE	c.4896G>T	p.M1632I	Missense	37/49	-
12-133219285-C-A	POLE	c.4759G>T	p.V1587F	Missense	37/49	-
12-133219565-C-G	POLE	c.4569G>C	p.M1523I	Missense	36/49	-
12-133219565-C-T	POLE	c.4569G>A	p.M1523I	Missense	36/49	-
12-133219565-C-A	POLE	c.4569G>T	p.M1523I	Missense	36/49	-
12-133219554-C-T	POLE	c.4580G>A	p.G1527D	Missense	36/49	-
12-133219527-A-C	POLE	c.4607T>G	p.L1536R	Missense	36/49	-
12-133219240-C-G	POLE	c.4804G>C	p.V1602L	Missense	37/49	-
12-133219533-T-A	POLE	c.4601A>T	p.H1534L	Missense	36/49	-
12-133219232-C-A	POLE	c.4812G>T	p.E1604D	Missense	37/49	-
12-133219234-C-T	POLE	c.4810G>A	p.E1604K	Missense	37/49	-
12-133219167-C-A	POLE	c.4877G>T	p.R1626L	Missense	37/49	-
12-133219434-G-A	POLE	c.4700C>T	p.A1567V	Missense	36/49	-
12-133219458-G-A	POLE	c.4676C>T	p.T1559I	Missense	36/49	-
12-133219183-C-T	POLE	c.4861G>A	p.V1621I	Missense	37/49	-
12-133219435-C-A	POLE	c.4699G>T	p.A1567S	Missense	36/49	-
12-133219183-C-A	POLE	c.4861G>T	p.V1621F	Missense	37/49	-
12-133219186-C-T	POLE	c.4858G>A	p.G1620R	Missense	37/49	-
12-133219186-C-G	POLE	c.4858G>C	p.G1620R	Missense	37/49	-
12-133219821-C-G	POLE	c.4540G>C	p.V1514L	Missense	35/49	-
12-133219821-C-A	POLE	c.4540G>T	p.V1514L	Missense	35/49	-
12-133219198-T-C	POLE	c.4846A>G	p.K1616E	Missense	37/49	-
12-133219207-C-T	POLE	c.4837G>A	p.V1613M	Missense	37/49	-
12-133219817-A-G	POLE	c.4544T>C	p.L1515P	Missense	35/49	-
12-133219534-G-A	POLE	c.4600C>T	p.H1534Y	Missense	36/49	-
12-133219568-C-A	POLE	c.4566G>T	p.Q1522H	Missense	36/49	-
12-133219568-C-G	POLE	c.4566G>C	p.Q1522H	Missense	36/49	-
12-133219225-G-A	POLE	c.4819C>T	p.P1607S	Missense	37/49	-
12-133219504-C-T	POLE	c.4630G>A	p.E1544K	Missense	36/49	-
12-133219503-T-C	POLE	c.4631A>G	p.E1544G	Missense	36/49	-
12-133219406-C-G	POLE	c.4728G>C	p.K1576N	Missense	36/49	-
12-133219406-C-A	POLE	c.4728G>T	p.K1576N	Missense	36/49	-
12-133219302-C-A	POLE	c.4742G>T	p.G1581V	Missense	37/49	-
12-133219467-C-G	POLE	c.4667G>C	p.R1556P	Missense	36/49	-
12-133219314-T-C	POLE	c.4730A>G	p.E1577G	Missense	37/49	-
12-133219407-T-C	POLE	c.4727A>G	p.K1576R	Missense	36/49	-
12-133219501-G-T	POLE	c.4633C>A	p.L1545I	Missense	36/49	-
12-133219315-C-T	POLE	c.4729G>A	p.E1577K	Missense	37/49	-
12-133219432-T-A	POLE	c.4702A>T	p.I1568F	Missense	36/49	-
12-133219245-A-G	POLE	c.4799T>C	p.I1600T	Missense	37/49	-
12-133219465-C-T	POLE	c.4669G>A	p.A1557T	Missense	36/49	-
12-133219313-C-A	POLE	c.4731G>T	p.E1577D	Missense	37/49	-
12-133219242-G-C	POLE	c.4802C>G	p.P1601R	Missense	37/49	-
12-133219501-G-A	POLE	c.4633C>T	p.L1545F	Missense	36/49	-
12-133219510-C-T	POLE	c.4624G>A	p.G1542S	Missense	36/49	-
12-133219417-G-A	POLE	c.4717C>T	p.L1573F	Missense	36/49	-
12-133219509-C-T	POLE	c.4625G>A	p.G1542D	Missense	36/49	-
12-133218804-T-C	POLE	c.5132A>G	p.Q1711R	Missense	38/49	-
12-133218803-T-A	POLE	c.5133A>T	p.Q1711H	Missense	38/49	-
12-133218803-T-G	POLE	c.5133A>C	p.Q1711H	Missense	38/49	-
12-133218423-C-A	POLE	c.5188G>T	p.D1730Y	Missense	39/49	-
12-133218363-C-T	POLE	c.5248G>A	p.G1750R	Missense	39/49	-
12-133218363-C-G	POLE	c.5248G>C	p.G1750R	Missense	39/49	-
12-133218290-T-C	POLE	c.5321A>G	p.Q1774R	Missense	39/49	-
12-133218841-C-A	POLE	c.5095G>T	p.A1699S	Missense	38/49	-
12-133218384-G-C	POLE	c.5227C>G	p.H1743D	Missense	39/49	-
12-133218366-C-G	POLE	c.5245G>C	p.E1749Q	Missense	39/49	-
12-133218284-G-A	POLE	c.5327C>T	p.A1776V	Missense	39/49	-
12-133218814-A-C	POLE	c.5122T>G	p.F1708V	Missense	38/49	-
12-133218815-C-G	POLE	c.5121G>C	p.E1707D	Missense	38/49	-
12-133218375-T-G	POLE	c.5236A>C	p.N1746H	Missense	39/49	-
12-133218412-G-C	POLE	c.5199C>G	p.N1733K	Missense	39/49	-
12-133218412-G-T	POLE	c.5199C>A	p.N1733K	Missense	39/49	-
12-133218943-A-T	POLE	c.4993T>A	p.S1665T	Missense	38/49	-
12-133218816-T-G	POLE	c.5120A>C	p.E1707A	Missense	38/49	-
12-133219104-A-G	POLE	c.4940T>C	p.F1647S	Missense	37/49	-
12-133218826-G-C	POLE	c.5110C>G	p.L1704V	Missense	38/49	-
12-133218423-C-G	POLE	c.5188G>C	p.D1730H	Missense	39/49	-
12-133218420-G-A	POLE	c.5191C>T	p.L1731F	Missense	39/49	-
12-133218293-C-A	POLE	c.5318G>T	p.G1773V	Missense	39/49	-
12-133218936-A-G	POLE	c.5000T>C	p.F1667S	Missense	38/49	-
12-133218916-C-A	POLE	c.5020G>T	p.A1674S	Missense	38/49	-
12-133218940-T-C	POLE	c.4996A>G	p.T1666A	Missense	38/49	-
12-133218835-C-T	POLE	c.5101G>A	p.D1701N	Missense	38/49	-
12-133218975-T-A	POLE	c.4961A>T	p.H1654L	Missense	38/49	-
12-133218807-T-G	POLE	c.5129A>C	p.D1710A	Missense	38/49	-
12-133218981-T-C	POLE	c.4955A>G	p.Y1652C	Missense	38/49	-
12-133218350-A-C	POLE	c.5261T>G	p.M1754R	Missense	39/49	-
12-133218837-T-A	POLE	c.5099A>T	p.D1700V	Missense	38/49	-
12-133218931-A-G	POLE	c.5005T>C	p.S1669P	Missense	38/49	-
12-133218402-T-G	POLE	c.5209A>C	p.N1737H	Missense	39/49	-
12-133218362-C-T	POLE	c.5249G>A	p.G1750E	Missense	39/49	-
12-133218432-C-G	POLE	c.5179G>C	p.V1727L	Missense	39/49	-
12-133218432-C-A	POLE	c.5179G>T	p.V1727L	Missense	39/49	-
12-133218312-C-T	POLE	c.5299G>A	p.E1767K	Missense	39/49	-
12-133219092-C-A	POLE	c.4952G>T	p.R1651M	Missense	37/49	-
12-133218924-A-G	POLE	c.5012T>C	p.L1671P	Missense	38/49	-
12-133218777-C-T	POLE	c.5159G>A	p.G1720D	Missense	38/49	-
12-133218363-C-A	POLE	c.5248G>T	p.G1750W	Missense	39/49	-
12-133218294-C-A	POLE	c.5317G>T	p.G1773C	Missense	39/49	-
12-133218881-C-A	POLE	c.5055G>T	p.W1685C	Missense	38/49	-
12-133218881-C-G	POLE	c.5055G>C	p.W1685C	Missense	38/49	-
12-133218351-T-G	POLE	c.5260A>C	p.M1754L	Missense	39/49	-
12-133218351-T-A	POLE	c.5260A>T	p.M1754L	Missense	39/49	-
12-133218837-T-C	POLE	c.5099A>G	p.D1700G	Missense	38/49	-
12-133218288-C-T	POLE	c.5323G>A	p.A1775T	Missense	39/49	-
12-133218817-C-G	POLE	c.5119G>C	p.E1707Q	Missense	38/49	-
12-133218366-C-T	POLE	c.5245G>A	p.E1749K	Missense	39/49	-
12-133218834-T-G	POLE	c.5102A>C	p.D1701A	Missense	38/49	-
12-133212549-G-C	POLE	c.5740C>G	p.L1914V	Missense	42/49	-
12-133215868-C-A	POLE	c.5395G>T	p.V1799F	Missense	40/49	-
12-133215853-T-C	POLE	c.5410A>G	p.K1804E	Missense	40/49	-
12-133214673-T-A	POLE	c.5605A>T	p.N1869Y	Missense	41/49	-
12-133215798-T-A	POLE	c.5465A>T	p.Y1822F	Missense	40/49	-
12-133215862-C-G	POLE	c.5401G>C	p.G1801R	Missense	40/49	-
12-133218242-T-C	POLE	c.5369A>G	p.N1790S	Missense	39/49	-
12-133215862-C-T	POLE	c.5401G>A	p.G1801S	Missense	40/49	-
12-133215811-C-T	POLE	c.5452G>A	p.V1818M	Missense	40/49	-
12-133215727-T-G	POLE	c.5536A>C	p.K1846Q	Missense	40/49	-
12-133215839-C-A	POLE	c.5424G>T	p.Q1808H	Missense	40/49	-
12-133212549-G-T	POLE	c.5740C>A	p.L1914I	Missense	42/49	-
12-133214655-T-A	POLE	c.5623A>T	p.T1875S	Missense	41/49	-
12-133212576-T-C	POLE	c.5713A>G	p.I1905V	Missense	42/49	-
12-133212549-G-A	POLE	c.5740C>T	p.L1914F	Missense	42/49	-
12-133215848-C-G	POLE	c.5415G>C	p.E1805D	Missense	40/49	-
12-133215848-C-A	POLE	c.5415G>T	p.E1805D	Missense	40/49	-
12-133215726-T-G	POLE	c.5537A>C	p.K1846T	Missense	40/49	-
12-133214640-C-G	POLE	c.5638G>C	p.V1880L	Missense	41/49	-
12-133214640-C-A	POLE	c.5638G>T	p.V1880L	Missense	41/49	-
12-133212557-C-A	POLE	c.5732G>T	p.W1911L	Missense	42/49	-
12-133215843-G-A	POLE	c.5420C>T	p.T1807I	Missense	40/49	-
12-133215855-A-C	POLE	c.5408T>G	p.V1803G	Missense	40/49	-
12-133214628-T-C	POLE	c.5650A>G	p.I1884V	Missense	41/49	-
12-133212540-T-C	POLE	c.5749A>G	p.M1917V	Missense	42/49	-
12-133212566-G-A	POLE	c.5723C>T	p.S1908F	Missense	42/49	-
12-133212566-G-C	POLE	c.5723C>G	p.S1908C	Missense	42/49	-
12-133215820-C-G	POLE	c.5443G>C	p.D1815H	Missense	40/49	-
12-133214693-G-A	POLE	c.5585C>T	p.S1862L	Missense	41/49	-
12-133214673-T-C	POLE	c.5605A>G	p.N1869D	Missense	41/49	-
12-133215816-T-C	POLE	c.5447A>G	p.N1816S	Missense	40/49	-
12-133212539-A-T	POLE	c.5750T>A	p.M1917K	Missense	42/49	-
12-133215828-A-G	POLE	c.5435T>C	p.I1812T	Missense	40/49	-
12-133215835-G-A	POLE	c.5428C>T	p.H1810Y	Missense	40/49	-
12-133215796-G-C	POLE	c.5467C>G	p.R1823G	Missense	40/49	-
12-133214700-C-T	POLE	c.5578G>A	p.G1860R	Missense	41/49	-
12-133218266-T-C	POLE	c.5345A>G	p.Y1782C	Missense	39/49	-
12-133214606-G-A	POLE	c.5672C>T	p.T1891I	Missense	41/49	-
12-133212600-T-G	POLE	c.5689A>C	p.K1897Q	Missense	42/49	-
12-133214710-G-T	POLE	c.5568C>A	p.F1856L	Missense	41/49	-
12-133214710-G-C	POLE	c.5568C>G	p.F1856L	Missense	41/49	-
12-133212527-T-A	POLE	c.5762A>T	p.N1921I	Missense	42/49	-
12-133212521-C-T	POLE	c.5768G>A	p.G1923D	Missense	42/49	-
12-133212527-T-C	POLE	c.5762A>G	p.N1921S	Missense	42/49	-
12-133215731-C-G	POLE	c.5532G>C	p.M1844I	Missense	40/49	-
12-133215731-C-T	POLE	c.5532G>A	p.M1844I	Missense	40/49	-
12-133215731-C-A	POLE	c.5532G>T	p.M1844I	Missense	40/49	-
12-133215729-A-C	POLE	c.5534T>G	p.M1845R	Missense	40/49	-
12-133215754-G-T	POLE	c.5509C>A	p.L1837M	Missense	40/49	-
12-133215714-A-G	POLE	c.5549T>C	p.L1850P	Missense	40/49	-
12-133214603-C-A	POLE	c.5675G>T	p.S1892I	Missense	41/49	-
12-133215745-T-G	POLE	c.5518A>C	p.T1840P	Missense	40/49	-
12-133212525-A-T	POLE	c.5764T>A	p.Y1922N	Missense	42/49	-
12-133215742-G-A	POLE	c.5521C>T	p.L1841F	Missense	40/49	-
12-133214724-G-A	POLE	c.5554C>T	p.L1852F	Missense	41/49	-
12-133212524-T-C	POLE	c.5765A>G	p.Y1922C	Missense	42/49	-
12-133212578-G-A	POLE	c.5711C>T	p.T1904I	Missense	42/49	-
12-133214600-C-T	POLE	c.5678G>A	p.S1893N	Missense	41/49	-
12-133212518-C-T	POLE	c.5771G>A	p.G1924E	Missense	42/49	-
12-133210867-G-A	POLE	c.5909C>T	p.S1970F	Missense	43/49	-
12-133209372-A-G	POLE	c.6014T>C	p.V2005A	Missense	44/49	-
12-133210907-C-G	POLE	c.5869G>C	p.E1957Q	Missense	43/49	-
12-133210786-A-C	POLE	c.5990T>G	p.L1997R	Missense	43/49	-
12-133210910-C-G	POLE	c.5866G>C	p.E1956Q	Missense	43/49	-
12-133209372-A-T	POLE	c.6014T>A	p.V2005E	Missense	44/49	-
12-133209289-G-A	POLE	c.6097C>T	p.L2033F	Missense	44/49	-
12-133210871-C-T	POLE	c.5905G>A	p.E1969K	Missense	43/49	-
12-133209291-T-C	POLE	c.6095A>G	p.Q2032R	Missense	44/49	-
12-133210892-C-T	POLE	c.5884G>A	p.E1962K	Missense	43/49	-
12-133210895-C-T	POLE	c.5881G>A	p.G1961R	Missense	43/49	-
12-133210895-C-G	POLE	c.5881G>C	p.G1961R	Missense	43/49	-
12-133209294-C-T	POLE	c.6092G>A	p.S2031N	Missense	44/49	-
12-133209076-T-C	POLE	c.6155A>G	p.Q2052R	Missense	45/49	-
12-133210900-C-G	POLE	c.5876G>C	p.R1959T	Missense	43/49	-
12-133209303-C-A	POLE	c.6083G>T	p.R2028M	Missense	44/49	-
12-133210900-C-T	POLE	c.5876G>A	p.R1959K	Missense	43/49	-
12-133210907-C-T	POLE	c.5869G>A	p.E1957K	Missense	43/49	-
12-133209079-G-A	POLE	c.6152C>T	p.S2051F	Missense	45/49	-
12-133209085-G-A	POLE	c.6146C>T	p.T2049I	Missense	45/49	-
12-133209094-C-A	POLE	c.6137G>T	p.G2046V	Missense	45/49	-
12-133210900-C-A	POLE	c.5876G>T	p.R1959I	Missense	43/49	-
12-133209321-C-A	POLE	c.6065G>T	p.S2022I	Missense	44/49	-
12-133209324-C-A	POLE	c.6062G>T	p.G2021V	Missense	44/49	-
12-133210811-C-G	POLE	c.5965G>C	p.A1989P	Missense	43/49	-
12-133210951-T-C	POLE	c.5825A>G	p.K1942R	Missense	43/49	-
12-133210955-G-C	POLE	c.5821C>G	p.Q1941E	Missense	43/49	-
12-133209353-C-G	POLE	c.6033G>C	p.M2011I	Missense	44/49	-
12-133209353-C-A	POLE	c.6033G>T	p.M2011I	Missense	44/49	-
12-133209346-C-G	POLE	c.6040G>C	p.G2014R	Missense	44/49	-
12-133210828-A-C	POLE	c.5948T>G	p.L1983W	Missense	43/49	-
12-133210933-T-C	POLE	c.5843A>G	p.D1948G	Missense	43/49	-
12-133209354-A-T	POLE	c.6032T>A	p.M2011K	Missense	44/49	-
12-133210942-C-G	POLE	c.5834G>C	p.G1945A	Missense	43/49	-
12-133210957-G-A	POLE	c.5819C>T	p.S1940F	Missense	43/49	-
12-133210790-A-C	POLE	c.5986T>G	p.F1996V	Missense	43/49	-
12-133209355-T-G	POLE	c.6031A>C	p.M2011L	Missense	44/49	-
12-133209355-T-A	POLE	c.6031A>T	p.M2011L	Missense	44/49	-
12-133209309-C-A	POLE	c.6077G>T	p.R2026M	Missense	44/49	-
12-133212483-C-T	POLE	c.5806G>A	p.G1936R	Missense	42/49	-
12-133212483-C-G	POLE	c.5806G>C	p.G1936R	Missense	42/49	-
12-133210933-T-A	POLE	c.5843A>T	p.D1948V	Missense	43/49	-
12-133210937-C-G	POLE	c.5839G>C	p.E1947Q	Missense	43/49	-
12-133210943-C-T	POLE	c.5833G>A	p.G1945R	Missense	43/49	-
12-133210943-C-G	POLE	c.5833G>C	p.G1945R	Missense	43/49	-
12-133210857-C-G	POLE	c.5919G>C	p.E1973D	Missense	43/49	-
12-133212486-A-G	POLE	c.5803T>C	p.C1935R	Missense	42/49	-
12-133210790-A-G	POLE	c.5986T>C	p.F1996L	Missense	43/49	-
12-133210788-G-T	POLE	c.5988C>A	p.F1996L	Missense	43/49	-
12-133210788-G-C	POLE	c.5988C>G	p.F1996L	Missense	43/49	-
12-133209031-G-A	POLE	c.6200C>T	p.T2067I	Missense	45/49	-
12-133209062-T-C	POLE	c.6169A>G	p.N2057D	Missense	45/49	-
12-133209032-T-C	POLE	c.6199A>G	p.T2067A	Missense	45/49	-
12-133209001-G-A	POLE	c.6230C>T	p.S2077F	Missense	45/49	-
12-133202347-C-A	POLE	c.6541G>T	p.V2181F	Missense	47/49	-
12-133209046-C-A	POLE	c.6185G>T	p.S2062I	Missense	45/49	-
12-133202352-C-G	POLE	c.6536G>C	p.G2179A	Missense	47/49	-
12-133209015-C-G	POLE	c.6216G>C	p.K2072N	Missense	45/49	-
12-133209015-C-A	POLE	c.6216G>T	p.K2072N	Missense	45/49	-
12-133202335-A-T	POLE	c.6553T>A	p.W2185R	Missense	47/49	-
12-133208975-T-G	POLE	c.6256A>C	p.M2086L	Missense	45/49	-
12-133208975-T-A	POLE	c.6256A>T	p.M2086L	Missense	45/49	-
12-133202756-T-A	POLE	c.6478A>T	p.S2160C	Missense	46/49	-
12-133202758-C-A	POLE	c.6476G>T	p.R2159L	Missense	46/49	-
12-133209045-G-C	POLE	c.6186C>G	p.S2062R	Missense	45/49	-
12-133209047-T-G	POLE	c.6184A>C	p.S2062R	Missense	45/49	-
12-133208973-C-G	POLE	c.6258G>C	p.M2086I	Missense	45/49	-
12-133208973-C-A	POLE	c.6258G>T	p.M2086I	Missense	45/49	-
12-133202711-A-C	POLE	c.6523T>G	p.F2175V	Missense	46/49	-
12-133202716-G-C	POLE	c.6518C>G	p.S2173C	Missense	46/49	-
12-133209010-A-G	POLE	c.6221T>C	p.V2074A	Missense	45/49	-
12-133209052-G-A	POLE	c.6179C>T	p.T2060I	Missense	45/49	-
12-133209055-A-C	POLE	c.6176T>G	p.L2059R	Missense	45/49	-
12-133202753-A-T	POLE	c.6481T>A	p.C2161S	Missense	46/49	-
12-133202752-C-G	POLE	c.6482G>C	p.C2161S	Missense	46/49	-
12-133202889-G-C	POLE	c.6345C>G	p.D2115E	Missense	46/49	-
12-133202889-G-T	POLE	c.6345C>A	p.D2115E	Missense	46/49	-
12-133202765-T-C	POLE	c.6469A>G	p.I2157V	Missense	46/49	-
12-133202785-G-A	POLE	c.6449C>T	p.S2150F	Missense	46/49	-
12-133208941-A-C	POLE	c.6290T>G	p.L2097R	Missense	45/49	-
12-133202813-C-G	POLE	c.6421G>C	p.E2141Q	Missense	46/49	-
12-133202305-C-G	POLE	c.6583G>C	p.D2195H	Missense	47/49	-
12-133208915-T-C	POLE	c.6316A>G	p.K2106E	Missense	45/49	-
12-133202315-C-A	POLE	c.6573G>T	p.Q2191H	Missense	47/49	-
12-133202315-C-G	POLE	c.6573G>C	p.Q2191H	Missense	47/49	-
12-133208921-A-G	POLE	c.6310T>C	p.F2104L	Missense	45/49	-
12-133208919-G-T	POLE	c.6312C>A	p.F2104L	Missense	45/49	-
12-133202743-C-A	POLE	c.6491G>T	p.C2164F	Missense	46/49	-
12-133202822-A-C	POLE	c.6412T>G	p.F2138V	Missense	46/49	-
12-133202810-C-A	POLE	c.6424G>T	p.A2142S	Missense	46/49	-
12-133202747-A-T	POLE	c.6487T>A	p.F2163I	Missense	46/49	-
12-133202764-A-T	POLE	c.6470T>A	p.I2157N	Missense	46/49	-
12-133208929-G-T	POLE	c.6302C>A	p.A2101D	Missense	45/49	-
12-133202825-C-G	POLE	c.6409G>C	p.E2137Q	Missense	46/49	-
12-133202899-A-G	POLE	c.6335T>C	p.L2112P	Missense	46/49	-
12-133202903-C-T	POLE	c.6331G>A	p.V2111M	Missense	46/49	-
12-133202823-C-G	POLE	c.6411G>C	p.E2137D	Missense	46/49	-
12-133202823-C-A	POLE	c.6411G>T	p.E2137D	Missense	46/49	-
12-133208957-C-A	POLE	c.6274G>T	p.G2092C	Missense	45/49	-
12-133208939-T-C	POLE	c.6292A>G	p.N2098D	Missense	45/49	-
12-133202771-C-T	POLE	c.6463G>A	p.E2155K	Missense	46/49	-
12-133202880-G-C	POLE	c.6354C>G	p.I2118M	Missense	46/49	-
12-133202896-G-C	POLE	c.6338C>G	p.S2113C	Missense	46/49	-
12-133208908-A-G	POLE	c.6323T>C	p.V2108A	Missense	45/49	-
12-133202879-T-G	POLE	c.6355A>C	p.T2119P	Missense	46/49	-
12-133202774-G-T	POLE	c.6460C>A	p.P2154T	Missense	46/49	-
12-133202854-C-G	POLE	c.6380G>C	p.R2127P	Missense	46/49	-
12-133202804-A-G	POLE	c.6430T>C	p.F2144L	Missense	46/49	-
12-133202802-G-C	POLE	c.6432C>G	p.F2144L	Missense	46/49	-
12-133208904-G-C	POLE	c.6327C>G	p.C2109W	Missense	45/49	-
19-50902229-A-T	POLD1	c.121A>T	p.M41L	Missense	2/27	-
19-50902255-G-T	POLD1	c.147G>T	p.R49S	Missense	2/27	-
19-50902188-A-G	POLD1	c.80A>G	p.D27G	Missense	2/27	-
19-50902145-G-C	POLD1	c.37G>C	p.V13L	Missense	2/27	-
12-133201565-G-C	POLE	c.6673C>G	p.R2225G	Missense	48/49	-
12-133202287-T-G	POLE	c.6601A>C	p.M2201L	Missense	47/49	-
12-133202287-T-A	POLE	c.6601A>T	p.M2201L	Missense	47/49	-
12-133202269-G-C	POLE	c.6619C>G	p.L2207V	Missense	47/49	-
19-50902250-C-T	POLD1	c.142C>T	p.H48Y	Missense	2/27	-
12-133201551-C-G	POLE	c.6687G>C	p.E2229D	Missense	48/49	-
12-133201551-C-A	POLE	c.6687G>T	p.E2229D	Missense	48/49	-
19-50902173-T-C	POLD1	c.65T>C	p.L22P	Missense	2/27	-
12-133202298-G-T	POLE	c.6590C>A	p.S2197Y	Missense	47/49	-
12-133201502-T-C	POLE	c.6736A>G	p.I2246V	Missense	48/49	-
12-133202244-G-C	POLE	c.6644C>G	p.T2215S	Missense	47/49	-
12-133202245-T-A	POLE	c.6643A>T	p.T2215S	Missense	47/49	-
12-133201561-C-G	POLE	c.6677G>C	p.G2226A	Missense	48/49	-
12-133201553-C-T	POLE	c.6685G>A	p.E2229K	Missense	48/49	-
19-50902208-T-C	POLD1	c.100T>C	p.F34L	Missense	2/27	-
19-50902247-G-A	POLD1	c.139G>A	p.E47K	Missense	2/27	-
19-50902229-A-C	POLD1	c.121A>C	p.M41L	Missense	2/27	-
12-133202236-C-T	POLE	c.6652G>A	p.D2218N	Missense	47/49	-
12-133201577-A-G	POLE	c.6661T>C	p.C2221R	Missense	48/49	-
12-133201580-C-T	POLE	c.6658G>A	p.V2220I	Missense	48/49	-
19-50902208-T-A	POLD1	c.100T>A	p.F34I	Missense	2/27	-
12-133201541-G-A	POLE	c.6697C>T	p.P2233S	Missense	48/49	-
12-133201505-T-A	POLE	c.6733A>T	p.T2245S	Missense	48/49	-
12-133201540-G-A	POLE	c.6698C>T	p.P2233L	Missense	48/49	-
12-133201517-C-G	POLE	c.6721G>C	p.D2241H	Missense	48/49	-
12-133201514-A-G	POLE	c.6724T>C	p.F2242L	Missense	48/49	-
12-133201512-G-T	POLE	c.6726C>A	p.F2242L	Missense	48/49	-
12-133201512-G-C	POLE	c.6726C>G	p.F2242L	Missense	48/49	-
12-133201501-A-G	POLE	c.6737T>C	p.I2246T	Missense	48/49	-
12-133201547-T-C	POLE	c.6691A>G	p.S2231G	Missense	48/49	-
19-50902137-G-A	POLD1	c.29G>A	p.G10E	Missense	2/27	-
12-133201301-G-C	POLE	c.6843C>G	p.N2281K	Missense	49/49	-
19-50902255-G-C	POLD1	c.147G>C	p.R49S	Missense	2/27	-
19-50902140-C-A	POLD1	c.32C>A	p.P11H	Missense	2/27	-
12-133201390-T-G	POLE	c.6754A>C	p.M2252L	Missense	49/49	-
12-133201390-T-A	POLE	c.6754A>T	p.M2252L	Missense	49/49	-
12-133201304-C-G	POLE	c.6840G>C	p.K2280N	Missense	49/49	-
12-133201304-C-A	POLE	c.6840G>T	p.K2280N	Missense	49/49	-
12-133201307-C-A	POLE	c.6837G>T	p.Q2279H	Missense	49/49	-
12-133201307-C-G	POLE	c.6837G>C	p.Q2279H	Missense	49/49	-
12-133201321-C-T	POLE	c.6823G>A	p.E2275K	Missense	49/49	-
12-133201311-A-G	POLE	c.6833T>C	p.L2278P	Missense	49/49	-
12-133201382-C-A	POLE	c.6762G>T	p.Q2254H	Missense	49/49	-
12-133201382-C-G	POLE	c.6762G>C	p.Q2254H	Missense	49/49	-
12-133201316-C-G	POLE	c.6828G>C	p.W2276C	Missense	49/49	-
12-133201492-T-A	POLE	c.6746A>T	p.Q2249L	Missense	48/49	-
12-133201391-G-T	POLE	c.6753C>A	p.F2251L	Missense	49/49	-
12-133201391-G-C	POLE	c.6753C>G	p.F2251L	Missense	49/49	-
12-133201319-C-G	POLE	c.6825G>C	p.E2275D	Missense	49/49	-
12-133201319-C-A	POLE	c.6825G>T	p.E2275D	Missense	49/49	-
12-133201317-C-A	POLE	c.6827G>T	p.W2276L	Missense	49/49	-
19-50902200-C-A	POLD1	c.92C>A	p.P31Q	Missense	2/27	-
19-50902187-G-A	POLD1	c.79G>A	p.D27N	Missense	2/27	-
12-133201383-T-C	POLE	c.6761A>G	p.Q2254R	Missense	49/49	-
12-133201330-C-T	POLE	c.6814G>A	p.E2272K	Missense	49/49	-
19-50902628-G-C	POLD1	c.203G>C	p.G68A	Missense	3/27	-
19-50902269-A-T	POLD1	c.161A>T	p.E54V	Missense	2/27	-
19-50902280-C-G	POLD1	c.172C>G	p.L58V	Missense	2/27	-
19-50905131-G-A	POLD1	c.413G>A	p.C138Y	Missense	4/27	-
19-50905106-G-A	POLD1	c.388G>A	p.V130I	Missense	4/27	-
19-50905098-C-T	POLD1	c.380C>T	p.A127V	Missense	4/27	-
19-50905155-C-T	POLD1	c.437C>T	p.P146L	Missense	4/27	-
19-50905112-G-T	POLD1	c.394G>T	p.D132Y	Missense	4/27	-
19-50905154-C-T	POLD1	c.436C>T	p.P146S	Missense	4/27	-
19-50905101-T-C	POLD1	c.383T>C	p.F128S	Missense	4/27	-
19-50905320-T-G	POLD1	c.528T>G	p.S176R	Missense	5/27	-
19-50905320-T-A	POLD1	c.528T>A	p.S176R	Missense	5/27	-
19-50905318-A-C	POLD1	c.526A>C	p.S176R	Missense	5/27	-
19-50905308-C-G	POLD1	c.516C>G	p.I172M	Missense	5/27	-
19-50905301-T-C	POLD1	c.509T>C	p.L170S	Missense	5/27	-
19-50905302-G-T	POLD1	c.510G>T	p.L170F	Missense	5/27	-
19-50905302-G-C	POLD1	c.510G>C	p.L170F	Missense	5/27	-
19-50902310-G-T	POLD1	c.202G>T	p.G68W	Missense	2/27	-
19-50905270-C-T	POLD1	c.478C>T	p.H160Y	Missense	5/27	-
19-50905272-C-A	POLD1	c.480C>A	p.H160Q	Missense	5/27	-
19-50905264-C-A	POLD1	c.472C>A	p.P158T	Missense	5/27	-
19-50905172-G-T	POLD1	c.454G>T	p.A152S	Missense	4/27	-
19-50905342-G-T	POLD1	c.550G>T	p.G184W	Missense	5/27	-
19-50902736-A-G	POLD1	c.311A>G	p.Y104C	Missense	3/27	-
19-50905047-C-A	POLD1	c.329C>A	p.P110H	Missense	4/27	-
19-50905047-C-G	POLD1	c.329C>G	p.P110R	Missense	4/27	-
19-50905464-A-C	POLD1	c.592A>C	p.M198L	Missense	6/27	-
19-50905464-A-T	POLD1	c.592A>T	p.M198L	Missense	6/27	-
19-50902741-G-T	POLD1	c.316G>T	p.G106C	Missense	3/27	-
19-50905360-G-C	POLD1	c.568G>C	p.V190L	Missense	5/27	-
19-50905360-G-T	POLD1	c.568G>T	p.V190L	Missense	5/27	-
19-50902729-G-T	POLD1	c.304G>T	p.D102Y	Missense	3/27	-
19-50905343-G-T	POLD1	c.551G>T	p.G184V	Missense	5/27	-
19-50902681-G-T	POLD1	c.256G>T	p.A86S	Missense	3/27	-
19-50905095-G-T	POLD1	c.377G>T	p.R126L	Missense	4/27	-
19-50905049-G-C	POLD1	c.331G>C	p.V111L	Missense	4/27	-
19-50905049-G-T	POLD1	c.331G>T	p.V111L	Missense	4/27	-
19-50905053-C-A	POLD1	c.335C>A	p.P112H	Missense	4/27	-
19-50902682-C-G	POLD1	c.257C>G	p.A86G	Missense	3/27	-
19-50905478-C-G	POLD1	c.606C>G	p.H202Q	Missense	6/27	-
19-50902699-G-C	POLD1	c.274G>C	p.E92Q	Missense	3/27	-
19-50902681-G-C	POLD1	c.256G>C	p.A86P	Missense	3/27	-
19-50905476-C-A	POLD1	c.604C>A	p.H202N	Missense	6/27	-
19-50902734-T-A	POLD1	c.309T>A	p.H103Q	Missense	3/27	-
19-50902734-T-G	POLD1	c.309T>G	p.H103Q	Missense	3/27	-
19-50905569-G-C	POLD1	c.697G>C	p.V233L	Missense	6/27	-
19-50905569-G-T	POLD1	c.697G>T	p.V233L	Missense	6/27	-
19-50905479-G-T	POLD1	c.607G>T	p.G203W	Missense	6/27	-
19-50905561-G-A	POLD1	c.689G>A	p.G230D	Missense	6/27	-
19-50905530-G-C	POLD1	c.658G>C	p.V220L	Missense	6/27	-
19-50905559-G-T	POLD1	c.687G>T	p.Q229H	Missense	6/27	-
19-50905559-G-C	POLD1	c.687G>C	p.Q229H	Missense	6/27	-
19-50905554-G-C	POLD1	c.682G>C	p.E228Q	Missense	6/27	-
19-50905518-C-A	POLD1	c.646C>A	p.L216M	Missense	6/27	-
19-50905554-G-A	POLD1	c.682G>A	p.E228K	Missense	6/27	-
19-50905789-G-C	POLD1	c.837G>C	p.E279D	Missense	7/27	-
19-50905551-C-A	POLD1	c.679C>A	p.L227M	Missense	6/27	-
19-50905989-G-T	POLD1	c.961G>T	p.G321C	Missense	8/27	-
19-50905603-A-T	POLD1	c.731A>T	p.Y244F	Missense	6/27	-
19-50905504-G-T	POLD1	c.632G>T	p.R211L	Missense	6/27	-
19-50905986-G-T	POLD1	c.958G>T	p.A320S	Missense	8/27	-
19-50905981-A-T	POLD1	c.953A>T	p.E318V	Missense	8/27	-
19-50905887-G-C	POLD1	c.859G>C	p.E287Q	Missense	8/27	-
19-50905609-C-T	POLD1	c.737C>T	p.A246V	Missense	6/27	-
19-50905986-G-C	POLD1	c.958G>C	p.A320P	Missense	8/27	-
19-50905935-C-T	POLD1	c.907C>T	p.P303S	Missense	8/27	-
19-50905939-G-C	POLD1	c.911G>C	p.W304S	Missense	8/27	-
19-50905500-C-G	POLD1	c.628C>G	p.L210V	Missense	6/27	-
19-50905479-G-C	POLD1	c.607G>C	p.G203R	Missense	6/27	-
19-50905773-C-T	POLD1	c.821C>T	p.A274V	Missense	7/27	-
19-50905500-C-A	POLD1	c.628C>A	p.L210M	Missense	6/27	-
19-50905495-C-G	POLD1	c.623C>G	p.P208R	Missense	6/27	-
19-50905751-G-C	POLD1	c.799G>C	p.E267Q	Missense	7/27	-
19-50905745-T-A	POLD1	c.793T>A	p.W265R	Missense	7/27	-
19-50905745-T-C	POLD1	c.793T>C	p.W265R	Missense	7/27	-
19-50905546-G-C	POLD1	c.674G>C	p.R225P	Missense	6/27	-
19-50905484-C-A	POLD1	c.612C>A	p.H204Q	Missense	6/27	-
19-50905484-C-G	POLD1	c.612C>G	p.H204Q	Missense	6/27	-
19-50905608-G-A	POLD1	c.736G>A	p.A246T	Missense	6/27	-
19-50905968-A-T	POLD1	c.940A>T	p.S314C	Missense	8/27	-
19-50905536-C-T	POLD1	c.664C>T	p.P222S	Missense	6/27	-
19-50905599-C-T	POLD1	c.727C>T	p.P243S	Missense	6/27	-
19-50905893-G-A	POLD1	c.865G>A	p.D289N	Missense	8/27	-
19-50905896-G-C	POLD1	c.868G>C	p.V290L	Missense	8/27	-
19-50905896-G-T	POLD1	c.868G>T	p.V290L	Missense	8/27	-
19-50905911-G-C	POLD1	c.883G>C	p.V295L	Missense	8/27	-
19-50905911-G-T	POLD1	c.883G>T	p.V295L	Missense	8/27	-
19-50905903-G-T	POLD1	c.875G>T	p.W292L	Missense	8/27	-
19-50906773-C-G	POLD1	c.1161C>G	p.I387M	Missense	10/27	-
19-50909466-G-C	POLD1	c.1270G>C	p.V424L	Missense	11/27	-
19-50906801-A-G	POLD1	c.1189A>G	p.N397D	Missense	10/27	-
19-50909439-G-C	POLD1	c.1243G>C	p.V415L	Missense	11/27	-
19-50909439-G-T	POLD1	c.1243G>T	p.V415L	Missense	11/27	-
19-50906793-C-T	POLD1	c.1181C>T	p.T394I	Missense	10/27	-
19-50906762-T-G	POLD1	c.1150T>G	p.F384V	Missense	10/27	-
19-50909472-G-T	POLD1	c.1276G>T	p.G426C	Missense	11/27	-
19-50906757-C-T	POLD1	c.1145C>T	p.S382F	Missense	10/27	-
19-50906462-G-A	POLD1	c.1123G>A	p.E375K	Missense	9/27	-
19-50906448-G-A	POLD1	c.1109G>A	p.S370N	Missense	9/27	-
19-50906786-G-C	POLD1	c.1174G>C	p.V392L	Missense	10/27	-
19-50906783-G-T	POLD1	c.1171G>T	p.D391Y	Missense	10/27	-
19-50906785-C-G	POLD1	c.1173C>G	p.D391E	Missense	10/27	-
19-50906785-C-A	POLD1	c.1173C>A	p.D391E	Missense	10/27	-
19-50906781-C-G	POLD1	c.1169C>G	p.P390R	Missense	10/27	-
19-50906780-C-G	POLD1	c.1168C>G	p.P390A	Missense	10/27	-
19-50906777-G-T	POLD1	c.1165G>T	p.D389Y	Missense	10/27	-
19-50906772-T-A	POLD1	c.1160T>A	p.I387N	Missense	10/27	-
19-50906762-T-A	POLD1	c.1150T>A	p.F384I	Missense	10/27	-
19-50906396-C-G	POLD1	c.1057C>G	p.L353V	Missense	9/27	-
19-50906346-A-C	POLD1	c.1007A>C	p.Q336P	Missense	9/27	-
19-50906347-G-C	POLD1	c.1008G>C	p.Q336H	Missense	9/27	-
19-50906340-T-C	POLD1	c.1001T>C	p.V334A	Missense	9/27	-
19-50906435-G-C	POLD1	c.1096G>C	p.A366P	Missense	9/27	-
19-50906336-C-T	POLD1	c.997C>T	p.P333S	Missense	9/27	-
19-50906381-G-C	POLD1	c.1042G>C	p.E348Q	Missense	9/27	-
19-50906375-G-A	POLD1	c.1036G>A	p.E346K	Missense	9/27	-
19-50906375-G-C	POLD1	c.1036G>C	p.E346Q	Missense	9/27	-
19-50906429-C-A	POLD1	c.1090C>A	p.L364M	Missense	9/27	-
19-50906314-C-G	POLD1	c.975C>G	p.I325M	Missense	9/27	-
19-50906323-G-C	POLD1	c.984G>C	p.E328D	Missense	9/27	-
19-50906323-G-T	POLD1	c.984G>T	p.E328D	Missense	9/27	-
19-50906361-G-A	POLD1	c.1022G>A	p.G341D	Missense	9/27	-
19-50906816-G-C	POLD1	c.1204G>C	p.D402H	Missense	10/27	-
19-50906406-C-T	POLD1	c.1067C>T	p.T356I	Missense	9/27	-
19-50906377-G-C	POLD1	c.1038G>C	p.E346D	Missense	9/27	-
19-50906377-G-T	POLD1	c.1038G>T	p.E346D	Missense	9/27	-
19-50906432-G-A	POLD1	c.1093G>A	p.G365S	Missense	9/27	-
19-50906354-T-A	POLD1	c.1015T>A	p.S339T	Missense	9/27	-
19-50906816-G-T	POLD1	c.1204G>T	p.D402Y	Missense	10/27	-
19-50906819-C-A	POLD1	c.1207C>A	p.L403I	Missense	10/27	-
19-50906420-G-T	POLD1	c.1081G>T	p.A361S	Missense	9/27	-
19-50906318-C-T	POLD1	c.979C>T	p.P327S	Missense	9/27	-
19-50906432-G-C	POLD1	c.1093G>C	p.G365R	Missense	9/27	-
19-50906829-T-C	POLD1	c.1217T>C	p.L406P	Missense	10/27	-
19-50906415-C-A	POLD1	c.1076C>A	p.P359H	Missense	9/27	-
19-50906337-C-T	POLD1	c.998C>T	p.P333L	Missense	9/27	-
19-50909491-G-T	POLD1	c.1295G>T	p.R432L	Missense	11/27	-
19-50909516-G-T	POLD1	c.1320G>T	p.Q440H	Missense	11/27	-
19-50909674-G-T	POLD1	c.1394G>T	p.R465L	Missense	12/27	-
19-50910249-G-C	POLD1	c.1504G>C	p.D502H	Missense	13/27	-
19-50910273-G-C	POLD1	c.1528G>C	p.V510L	Missense	13/27	-
19-50910273-G-T	POLD1	c.1528G>T	p.V510L	Missense	13/27	-
19-50910366-G-C	POLD1	c.1621G>C	p.V541L	Missense	13/27	-
19-50910366-G-T	POLD1	c.1621G>T	p.V541L	Missense	13/27	-
19-50910249-G-T	POLD1	c.1504G>T	p.D502Y	Missense	13/27	-
19-50909550-G-C	POLD1	c.1354G>C	p.V452L	Missense	11/27	-
19-50909550-G-T	POLD1	c.1354G>T	p.V452L	Missense	11/27	-
19-50909500-C-T	POLD1	c.1304C>T	p.S435L	Missense	11/27	-
19-50909520-G-T	POLD1	c.1324G>T	p.G442C	Missense	11/27	-
19-50910352-C-G	POLD1	c.1607C>G	p.A536G	Missense	13/27	-
19-50910262-G-C	POLD1	c.1517G>C	p.R506P	Missense	13/27	-
19-50909549-G-C	POLD1	c.1353G>C	p.M451I	Missense	11/27	-
19-50909549-G-A	POLD1	c.1353G>A	p.M451I	Missense	11/27	-
19-50909549-G-T	POLD1	c.1353G>T	p.M451I	Missense	11/27	-
19-50909496-T-G	POLD1	c.1300T>G	p.S434A	Missense	11/27	-
19-50909542-T-C	POLD1	c.1346T>C	p.V449A	Missense	11/27	-
19-50910363-G-T	POLD1	c.1618G>T	p.G540C	Missense	13/27	-
19-50909671-T-A	POLD1	c.1391T>A	p.L464Q	Missense	12/27	-
19-50909664-G-C	POLD1	c.1384G>C	p.V462L	Missense	12/27	-
19-50909664-G-T	POLD1	c.1384G>T	p.V462L	Missense	12/27	-
19-50910251-C-G	POLD1	c.1506C>G	p.D502E	Missense	13/27	-
19-50909536-A-T	POLD1	c.1340A>T	p.K447M	Missense	11/27	-
19-50909706-G-T	POLD1	c.1426G>T	p.A476S	Missense	12/27	-
19-50909773-A-T	POLD1	c.1493A>T	p.Q498L	Missense	12/27	-
19-50910243-G-A	POLD1	c.1498G>A	p.G500R	Missense	13/27	-
19-50910243-G-C	POLD1	c.1498G>C	p.G500R	Missense	13/27	-
19-50909569-A-G	POLD1	c.1373A>G	p.D458G	Missense	11/27	-
19-50909707-C-T	POLD1	c.1427C>T	p.A476V	Missense	12/27	-
19-50909697-A-G	POLD1	c.1417A>G	p.T473A	Missense	12/27	-
19-50909716-T-C	POLD1	c.1436T>C	p.F479S	Missense	12/27	-
19-50909715-T-G	POLD1	c.1435T>G	p.F479V	Missense	12/27	-
19-50910381-C-A	POLD1	c.1636C>A	p.L546M	Missense	13/27	-
19-50909692-C-A	POLD1	c.1412C>A	p.S471Y	Missense	12/27	-
19-50910390-C-A	POLD1	c.1645C>A	p.R549S	Missense	13/27	-
19-50909568-G-T	POLD1	c.1372G>T	p.D458Y	Missense	11/27	-
19-50909727-G-C	POLD1	c.1447G>C	p.G483R	Missense	12/27	-
19-50909738-G-C	POLD1	c.1458G>C	p.K486N	Missense	12/27	-
19-50909738-G-T	POLD1	c.1458G>T	p.K486N	Missense	12/27	-
19-50909713-G-T	POLD1	c.1433G>T	p.S478I	Missense	12/27	-
19-50910387-A-T	POLD1	c.1642A>T	p.S548C	Missense	13/27	-
19-50909754-A-G	POLD1	c.1474A>G	p.S492G	Missense	12/27	-
19-50909665-T-G	POLD1	c.1385T>G	p.V462G	Missense	12/27	-
19-50910412-T-C	POLD1	c.1667T>C	p.V556A	Missense	13/27	-
19-50910381-C-G	POLD1	c.1636C>G	p.L546V	Missense	13/27	-
19-50909759-C-G	POLD1	c.1479C>G	p.I493M	Missense	12/27	-
19-50909676-G-A	POLD1	c.1396G>A	p.E466K	Missense	12/27	-
19-50909745-G-C	POLD1	c.1465G>C	p.V489L	Missense	12/27	-
19-50909739-G-C	POLD1	c.1459G>C	p.E487Q	Missense	12/27	-
19-50910340-C-T	POLD1	c.1595C>T	p.A532V	Missense	13/27	-
19-50910388-G-T	POLD1	c.1643G>T	p.S548I	Missense	13/27	-
19-50909772-C-A	POLD1	c.1492C>A	p.Q498K	Missense	12/27	-
19-50909740-A-T	POLD1	c.1460A>T	p.E487V	Missense	12/27	-
19-50910301-C-T	POLD1	c.1556C>T	p.P519L	Missense	13/27	-
19-50910304-T-C	POLD1	c.1559T>C	p.L520P	Missense	13/27	-
19-50910645-G-T	POLD1	c.1748G>T	p.G583V	Missense	14/27	-
19-50912423-T-G	POLD1	c.1937T>G	p.F646C	Missense	16/27	-
19-50910644-G-A	POLD1	c.1747G>A	p.G583R	Missense	14/27	-
19-50910644-G-C	POLD1	c.1747G>C	p.G583R	Missense	14/27	-
19-50912405-C-T	POLD1	c.1919C>T	p.T640I	Missense	16/27	-
19-50912798-G-C	POLD1	c.2029G>C	p.E677Q	Missense	17/27	-
19-50910635-G-C	POLD1	c.1738G>C	p.D580H	Missense	14/27	-
19-50910636-A-G	POLD1	c.1739A>G	p.D580G	Missense	14/27	-
19-50912398-A-G	POLD1	c.1912A>G	p.I638V	Missense	16/27	-
19-50910632-G-C	POLD1	c.1735G>C	p.E579Q	Missense	14/27	-
19-50910603-T-C	POLD1	c.1706T>C	p.L569P	Missense	14/27	-
19-50912421-G-C	POLD1	c.1935G>C	p.E645D	Missense	16/27	-
19-50912421-G-T	POLD1	c.1935G>T	p.E645D	Missense	16/27	-
19-50910603-T-G	POLD1	c.1706T>G	p.L569R	Missense	14/27	-
19-50912157-G-C	POLD1	c.1891G>C	p.G631R	Missense	15/27	-
19-50910585-C-T	POLD1	c.1688C>T	p.A563V	Missense	14/27	-
19-50910653-G-T	POLD1	c.1756G>T	p.V586F	Missense	14/27	-
19-50910614-G-C	POLD1	c.1717G>C	p.V573L	Missense	14/27	-
19-50912417-A-G	POLD1	c.1931A>G	p.D644G	Missense	16/27	-
19-50912417-A-C	POLD1	c.1931A>C	p.D644A	Missense	16/27	-
19-50910431-G-T	POLD1	c.1686G>T	p.Q562H	Missense	13/27	-
19-50910431-G-C	POLD1	c.1686G>C	p.Q562H	Missense	13/27	-
19-50912456-C-T	POLD1	c.1970C>T	p.P657L	Missense	16/27	-
19-50910629-G-T	POLD1	c.1732G>T	p.G578C	Missense	14/27	-
19-50912411-C-T	POLD1	c.1925C>T	p.T642I	Missense	16/27	-
19-50912437-G-C	POLD1	c.1951G>C	p.V651L	Missense	16/27	-
19-50912408-C-T	POLD1	c.1922C>T	p.P641L	Missense	16/27	-
19-50912452-C-A	POLD1	c.1966C>A	p.L656M	Missense	16/27	-
19-50912793-C-T	POLD1	c.2024C>T	p.A675V	Missense	17/27	-
19-50912447-G-T	POLD1	c.1961G>T	p.G654V	Missense	16/27	-
19-50912139-G-C	POLD1	c.1873G>C	p.G625R	Missense	15/27	-
19-50912445-G-T	POLD1	c.1959G>T	p.K653N	Missense	16/27	-
19-50912814-G-T	POLD1	c.2045G>T	p.R682L	Missense	17/27	-
19-50912145-G-A	POLD1	c.1879G>A	p.A627T	Missense	15/27	-
19-50912402-G-A	POLD1	c.1916G>A	p.R639K	Missense	16/27	-
19-50912816-C-T	POLD1	c.2047C>T	p.R683C	Missense	17/27	-
19-50912386-G-A	POLD1	c.1900G>A	p.E634K	Missense	16/27	-
19-50912065-C-G	POLD1	c.1799C>G	p.T600S	Missense	15/27	-
19-50912064-A-T	POLD1	c.1798A>T	p.T600S	Missense	15/27	-
19-50912101-T-C	POLD1	c.1835T>C	p.M612T	Missense	15/27	-
19-50912055-C-T	POLD1	c.1789C>T	p.P597S	Missense	15/27	-
19-50912430-G-C	POLD1	c.1944G>C	p.K648N	Missense	16/27	-
19-50912430-G-T	POLD1	c.1944G>T	p.K648N	Missense	16/27	-
19-50912043-T-C	POLD1	c.1777T>C	p.Y593H	Missense	15/27	-
19-50912112-C-A	POLD1	c.1846C>A	p.L616M	Missense	15/27	-
19-50912104-C-G	POLD1	c.1838C>G	p.A613G	Missense	15/27	-
19-50912115-T-G	POLD1	c.1849T>G	p.C617G	Missense	15/27	-
19-50912086-A-G	POLD1	c.1820A>G	p.Y607C	Missense	15/27	-
19-50917101-C-T	POLD1	c.2353C>T	p.H785Y	Missense	19/27	-
19-50917101-C-A	POLD1	c.2353C>A	p.H785N	Missense	19/27	-
19-50917095-T-A	POLD1	c.2347T>A	p.S783T	Missense	19/27	-
19-50917054-C-G	POLD1	c.2306C>G	p.A769G	Missense	19/27	-
19-50917058-G-C	POLD1	c.2310G>C	p.E770D	Missense	19/27	-
19-50917058-G-T	POLD1	c.2310G>T	p.E770D	Missense	19/27	-
19-50917096-C-T	POLD1	c.2348C>T	p.S783L	Missense	19/27	-
19-50917091-G-T	POLD1	c.2343G>T	p.W781C	Missense	19/27	-
19-50917091-G-C	POLD1	c.2343G>C	p.W781C	Missense	19/27	-
19-50917086-G-C	POLD1	c.2338G>C	p.D780H	Missense	19/27	-
19-50917088-C-A	POLD1	c.2340C>A	p.D780E	Missense	19/27	-
19-50917084-C-T	POLD1	c.2336C>T	p.A779V	Missense	19/27	-
19-50917083-G-A	POLD1	c.2335G>A	p.A779T	Missense	19/27	-
19-50917077-G-A	POLD1	c.2329G>A	p.E777K	Missense	19/27	-
19-50917075-G-T	POLD1	c.2327G>T	p.R776L	Missense	19/27	-
19-50917071-G-C	POLD1	c.2323G>C	p.G775R	Missense	19/27	-
19-50916773-G-C	POLD1	c.2245G>C	p.A749P	Missense	18/27	-
19-50912862-A-T	POLD1	c.2093A>T	p.N698I	Missense	17/27	-
19-50912828-G-T	POLD1	c.2059G>T	p.D687Y	Missense	17/27	-
19-50916754-G-C	POLD1	c.2226G>C	p.E742D	Missense	18/27	-
19-50916754-G-T	POLD1	c.2226G>T	p.E742D	Missense	18/27	-
19-50912907-G-T	POLD1	c.2138G>T	p.C713F	Missense	17/27	-
19-50917033-G-C	POLD1	c.2285G>C	p.R762P	Missense	19/27	-
19-50912885-G-T	POLD1	c.2116G>T	p.A706S	Missense	17/27	-
19-50912835-G-T	POLD1	c.2066G>T	p.R689L	Missense	17/27	-
19-50916720-C-T	POLD1	c.2192C>T	p.T731I	Missense	18/27	-
19-50916731-G-A	POLD1	c.2203G>A	p.V735M	Missense	18/27	-
19-50918078-T-C	POLD1	c.2395T>C	p.F799L	Missense	20/27	-
19-50918080-C-G	POLD1	c.2397C>G	p.F799L	Missense	20/27	-
19-50918076-A-G	POLD1	c.2393A>G	p.Y798C	Missense	20/27	-
19-50912882-G-A	POLD1	c.2113G>A	p.G705S	Missense	17/27	-
19-50916753-A-G	POLD1	c.2225A>G	p.E742G	Missense	18/27	-
19-50912879-A-G	POLD1	c.2110A>G	p.T704A	Missense	17/27	-
19-50916712-C-G	POLD1	c.2184C>G	p.I728M	Missense	18/27	-
19-50912908-C-G	POLD1	c.2139C>G	p.C713W	Missense	17/27	-
19-50918081-C-T	POLD1	c.2398C>T	p.P800S	Missense	20/27	-
19-50917024-T-G	POLD1	c.2276T>G	p.V759G	Missense	19/27	-
19-50912843-G-T	POLD1	c.2074G>T	p.A692S	Missense	17/27	-
19-50912906-T-G	POLD1	c.2137T>G	p.C713G	Missense	17/27	-
19-50917114-C-T	POLD1	c.2366C>T	p.P789L	Missense	19/27	-
19-50912918-T-G	POLD1	c.2149T>G	p.S717A	Missense	17/27	-
19-50916738-C-G	POLD1	c.2210C>G	p.S737C	Missense	18/27	-
19-50917039-G-A	POLD1	c.2291G>A	p.G764D	Missense	19/27	-
19-50912915-A-G	POLD1	c.2146A>G	p.I716V	Missense	17/27	-
19-50916770-A-G	POLD1	c.2242A>G	p.S748G	Missense	18/27	-
19-50917008-G-A	POLD1	c.2260G>A	p.G754S	Missense	19/27	-
19-50912835-G-C	POLD1	c.2066G>C	p.R689P	Missense	17/27	-
19-50916749-G-A	POLD1	c.2221G>A	p.V741M	Missense	18/27	-
19-50916735-A-G	POLD1	c.2207A>G	p.E736G	Missense	18/27	-
19-50912822-G-T	POLD1	c.2053G>T	p.V685F	Missense	17/27	-
19-50912846-C-A	POLD1	c.2077C>A	p.L693M	Missense	17/27	-
19-50918986-G-A	POLD1	c.2723G>A	p.R908K	Missense	22/27	-
19-50918117-C-G	POLD1	c.2434C>G	p.L812V	Missense	20/27	-
19-50918223-C-T	POLD1	c.2540C>T	p.S847L	Missense	20/27	-
19-50918209-C-G	POLD1	c.2526C>G	p.N842K	Missense	20/27	-
19-50918209-C-A	POLD1	c.2526C>A	p.N842K	Missense	20/27	-
19-50918115-G-C	POLD1	c.2432G>C	p.G811A	Missense	20/27	-
19-50919039-A-C	POLD1	c.2776A>C	p.I926L	Missense	22/27	-
19-50918181-G-T	POLD1	c.2498G>T	p.R833L	Missense	20/27	-
19-50918192-T-C	POLD1	c.2509T>C	p.C837R	Missense	20/27	-
19-50918186-G-A	POLD1	c.2503G>A	p.D835N	Missense	20/27	-
19-50918825-G-A	POLD1	c.2695G>A	p.A899T	Missense	21/27	-
19-50919030-C-T	POLD1	c.2767C>T	p.P923S	Missense	22/27	-
19-50918984-G-C	POLD1	c.2721G>C	p.M907I	Missense	22/27	-
19-50918984-G-T	POLD1	c.2721G>T	p.M907I	Missense	22/27	-
19-50918146-C-G	POLD1	c.2463C>G	p.H821Q	Missense	20/27	-
19-50918825-G-T	POLD1	c.2695G>T	p.A899S	Missense	21/27	-
19-50918717-C-T	POLD1	c.2587C>T	p.H863Y	Missense	21/27	-
19-50918817-G-A	POLD1	c.2687G>A	p.G896D	Missense	21/27	-
19-50918714-G-C	POLD1	c.2584G>C	p.A862P	Missense	21/27	-
19-50918786-G-A	POLD1	c.2656G>A	p.E886K	Missense	21/27	-
19-50918728-C-G	POLD1	c.2598C>G	p.D866E	Missense	21/27	-
19-50918728-C-A	POLD1	c.2598C>A	p.D866E	Missense	21/27	-
19-50918781-C-T	POLD1	c.2651C>T	p.T884I	Missense	21/27	-
19-50918198-C-G	POLD1	c.2515C>G	p.L839V	Missense	20/27	-
19-50918243-G-C	POLD1	c.2560G>C	p.D854H	Missense	20/27	-
19-50918778-T-C	POLD1	c.2648T>C	p.I883T	Missense	21/27	-
19-50918169-T-C	POLD1	c.2486T>C	p.L829P	Missense	20/27	-
19-50918774-G-C	POLD1	c.2644G>C	p.V882L	Missense	21/27	-
19-50918177-G-C	POLD1	c.2494G>C	p.V832L	Missense	20/27	-
19-50918177-G-T	POLD1	c.2494G>T	p.V832L	Missense	20/27	-
19-50918696-G-C	POLD1	c.2566G>C	p.D856H	Missense	21/27	-
19-50918732-A-G	POLD1	c.2602A>G	p.I868V	Missense	21/27	-
19-50919024-C-T	POLD1	c.2761C>T	p.R921C	Missense	22/27	-
19-50919037-T-G	POLD1	c.2774T>G	p.V925G	Missense	22/27	-
19-50918774-G-A	POLD1	c.2644G>A	p.V882I	Missense	21/27	-
19-50918237-C-T	POLD1	c.2554C>T	p.L852F	Missense	20/27	-
19-50918213-G-A	POLD1	c.2530G>A	p.V844I	Missense	20/27	-
19-50918759-G-T	POLD1	c.2629G>T	p.D877Y	Missense	21/27	-
19-50918123-T-C	POLD1	c.2440T>C	p.F814L	Missense	20/27	-
19-50918125-C-A	POLD1	c.2442C>A	p.F814L	Missense	20/27	-
19-50918188-C-G	POLD1	c.2505C>G	p.D835E	Missense	20/27	-
19-50918188-C-A	POLD1	c.2505C>A	p.D835E	Missense	20/27	-
19-50919031-C-G	POLD1	c.2768C>G	p.P923R	Missense	22/27	-
19-50919021-G-T	POLD1	c.2758G>T	p.D920Y	Missense	22/27	-
19-50918753-C-A	POLD1	c.2623C>A	p.R875S	Missense	21/27	-
19-50919031-C-T	POLD1	c.2768C>T	p.P923L	Missense	22/27	-
19-50918185-G-C	POLD1	c.2502G>C	p.R834S	Missense	20/27	-
19-50918185-G-T	POLD1	c.2502G>T	p.R834S	Missense	20/27	-
19-50919025-G-A	POLD1	c.2762G>A	p.R921H	Missense	22/27	-
19-50918238-T-C	POLD1	c.2555T>C	p.L852P	Missense	20/27	-
19-50919058-G-A	POLD1	c.2795G>A	p.G932D	Missense	22/27	-
19-50919719-G-T	POLD1	c.2887G>T	p.A963S	Missense	23/27	-
19-50919082-A-T	POLD1	c.2819A>T	p.E940V	Missense	22/27	-
19-50919869-G-A	POLD1	c.2956G>A	p.G986R	Missense	24/27	-
19-50919869-G-C	POLD1	c.2956G>C	p.G986R	Missense	24/27	-
19-50919078-T-G	POLD1	c.2815T>G	p.S939A	Missense	22/27	-
19-50919739-C-G	POLD1	c.2907C>G	p.I969M	Missense	23/27	-
19-50919896-C-A	POLD1	c.2983C>A	p.L995I	Missense	24/27	-
19-50919067-C-T	POLD1	c.2804C>T	p.A935V	Missense	22/27	-
19-50919960-G-C	POLD1	c.3047G>C	p.R1016P	Missense	24/27	-
19-50920310-T-A	POLD1	c.3076T>A	p.C1026S	Missense	25/27	-
19-50920311-G-C	POLD1	c.3077G>C	p.C1026S	Missense	25/27	-
19-50919962-A-T	POLD1	c.3049A>T	p.T1017S	Missense	24/27	-
19-50919911-G-A	POLD1	c.2998G>A	p.G1000S	Missense	24/27	-
19-50919726-C-T	POLD1	c.2894C>T	p.P965L	Missense	23/27	-
19-50919058-G-T	POLD1	c.2795G>T	p.G932V	Missense	22/27	-
19-50919060-G-C	POLD1	c.2797G>C	p.V933L	Missense	22/27	-
19-50919874-C-G	POLD1	c.2961C>G	p.D987E	Missense	24/27	-
19-50919874-C-A	POLD1	c.2961C>A	p.D987E	Missense	24/27	-
19-50919980-G-A	POLD1	c.3067G>A	p.G1023R	Missense	24/27	-
19-50919980-G-C	POLD1	c.3067G>C	p.G1023R	Missense	24/27	-
19-50919654-A-G	POLD1	c.2822A>G	p.D941G	Missense	23/27	-
19-50920320-G-A	POLD1	c.3086G>A	p.C1029Y	Missense	25/27	-
19-50919760-G-C	POLD1	c.2928G>C	p.E976D	Missense	23/27	-
19-50919760-G-T	POLD1	c.2928G>T	p.E976D	Missense	23/27	-
19-50919908-G-A	POLD1	c.2995G>A	p.V999M	Missense	24/27	-
19-50919078-T-C	POLD1	c.2815T>C	p.S939P	Missense	22/27	-
19-50920307-G-T	POLD1	c.3073G>T	p.V1025L	Missense	25/27	-
19-50919923-G-C	POLD1	c.3010G>C	p.A1004P	Missense	24/27	-
19-50920319-T-A	POLD1	c.3085T>A	p.C1029S	Missense	25/27	-
19-50920320-G-C	POLD1	c.3086G>C	p.C1029S	Missense	25/27	-
19-50919731-C-G	POLD1	c.2899C>G	p.L967V	Missense	23/27	-
19-50919072-A-C	POLD1	c.2809A>C	p.M937L	Missense	22/27	-
19-50919662-T-C	POLD1	c.2830T>C	p.F944L	Missense	23/27	-
19-50919664-C-A	POLD1	c.2832C>A	p.F944L	Missense	23/27	-
19-50919664-C-G	POLD1	c.2832C>G	p.F944L	Missense	23/27	-
19-50919771-A-T	POLD1	c.2939A>T	p.E980V	Missense	23/27	-
19-50920313-G-C	POLD1	c.3079G>C	p.E1027Q	Missense	25/27	-
19-50919657-C-G	POLD1	c.2825C>G	p.P942R	Missense	23/27	-
19-50919761-G-T	POLD1	c.2929G>T	p.G977C	Missense	23/27	-
19-50919653-G-A	POLD1	c.2821G>A	p.D941N	Missense	23/27	-
19-50919653-G-C	POLD1	c.2821G>C	p.D941H	Missense	23/27	-
19-50919728-C-G	POLD1	c.2896C>G	p.L966V	Missense	23/27	-
19-50919714-A-G	POLD1	c.2882A>G	p.Q961R	Missense	23/27	-
19-50919724-G-T	POLD1	c.2892G>T	p.K964N	Missense	23/27	-
19-50919774-C-T	POLD1	c.2942C>T	p.A981V	Missense	23/27	-
19-50920316-T-C	POLD1	c.3082T>C	p.F1028L	Missense	25/27	-
19-50920318-C-A	POLD1	c.3084C>A	p.F1028L	Missense	25/27	-
19-50920318-C-G	POLD1	c.3084C>G	p.F1028L	Missense	25/27	-
19-50919947-T-G	POLD1	c.3034T>G	p.C1012G	Missense	24/27	-
19-50919945-G-A	POLD1	c.3032G>A	p.C1011Y	Missense	24/27	-
19-50919939-G-T	POLD1	c.3026G>T	p.R1009L	Missense	24/27	-
X-47429012-G-T	ARAF	c.1375G>T	p.G459W	Missense	13/16	-
X-47430336-C-G	ARAF	c.1611C>G	p.N537K	Missense	15/16	-
X-47430336-C-A	ARAF	c.1611C>A	p.N537K	Missense	15/16	-
X-47429019-A-G	ARAF	c.1382A>G	p.Q461R	Missense	13/16	-
19-50921125-G-A	POLD1	c.3245G>A	p.R1082H	Missense	27/27	-
19-50921109-C-G	POLD1	c.3229C>G	p.P1077A	Missense	27/27	-
19-50920526-G-C	POLD1	c.3218G>C	p.S1073T	Missense	26/27	-
19-50920508-A-T	POLD1	c.3200A>T	p.E1067V	Missense	26/27	-
19-50921103-G-C	POLD1	c.3223G>C	p.D1075H	Missense	27/27	-
19-50921109-C-T	POLD1	c.3229C>T	p.P1077S	Missense	27/27	-
19-50921123-G-C	POLD1	c.3243G>C	p.M1081I	Missense	27/27	-
19-50921123-G-T	POLD1	c.3243G>T	p.M1081I	Missense	27/27	-
2-29519915-C-G	ALK	c.1656G>C	p.M552I	Missense	9/29	-
2-29519915-C-A	ALK	c.1656G>T	p.M552I	Missense	9/29	-
19-50920481-G-A	POLD1	c.3173G>A	p.C1058Y	Missense	26/27	-
19-50920504-C-G	POLD1	c.3196C>G	p.H1066D	Missense	26/27	-
19-50920495-G-T	POLD1	c.3187G>T	p.G1063C	Missense	26/27	-
19-50920509-G-C	POLD1	c.3201G>C	p.E1067D	Missense	26/27	-
19-50920509-G-T	POLD1	c.3201G>T	p.E1067D	Missense	26/27	-
19-50920445-C-G	POLD1	c.3137C>G	p.A1046G	Missense	26/27	-
19-50920438-C-G	POLD1	c.3130C>G	p.L1044V	Missense	26/27	-
19-50921169-C-G	POLD1	c.3289C>G	p.R1097G	Missense	27/27	-
19-50920475-C-A	POLD1	c.3167C>A	p.T1056K	Missense	26/27	-
19-50921129-G-C	POLD1	c.3249G>C	p.K1083N	Missense	27/27	-
19-50921129-G-T	POLD1	c.3249G>T	p.K1083N	Missense	27/27	-
19-50921151-G-A	POLD1	c.3271G>A	p.D1091N	Missense	27/27	-
19-50920429-G-C	POLD1	c.3121G>C	p.V1041L	Missense	26/27	-
19-50920429-G-T	POLD1	c.3121G>T	p.V1041L	Missense	26/27	-
19-50921148-G-A	POLD1	c.3268G>A	p.E1090K	Missense	27/27	-
19-50920462-T-C	POLD1	c.3154T>C	p.S1052P	Missense	26/27	-
2-29754873-G-T	ALK	c.1062C>A	p.H354Q	Missense	4/29	-
2-29754873-G-C	ALK	c.1062C>G	p.H354Q	Missense	4/29	-
19-50921179-G-T	POLD1	c.3299G>T	p.G1100V	Missense	27/27	-
1-243716086-A-G	AKT3	c.1108T>C	p.S370P	Missense	11/14	-
1-243716177-C-T	AKT3	c.1017G>A	p.M339I	Missense	11/14	-
19-50921133-G-C	POLD1	c.3253G>C	p.V1085L	Missense	27/27	-
19-50921133-G-T	POLD1	c.3253G>T	p.V1085L	Missense	27/27	-
19-50920474-A-T	POLD1	c.3166A>T	p.T1056S	Missense	26/27	-
19-50921197-C-A	POLD1	c.3317C>A	p.A1106D	Missense	27/27	-
19-50920456-C-A	POLD1	c.3148C>A	p.R1050S	Missense	26/27	-
19-50920466-G-T	POLD1	c.3158G>T	p.R1053L	Missense	26/27	-
19-50921190-C-A	POLD1	c.3310C>A	p.P1104T	Missense	27/27	-
12-133220132-G-C	POLE	c.4305C>G	p.F1435L	Missense	34/49	-
12-133219886-T-A	POLE	c.4475A>T	p.H1492L	Missense	35/49	-
19-50921162-G-C	POLD1	c.3282G>C	p.Q1094H	Missense	27/27	-
19-50920453-G-A	POLD1	c.3145G>A	p.E1049K	Missense	26/27	-
19-50920344-A-G	POLD1	c.3110A>G	p.Y1037C	Missense	25/27	-
19-50920430-T-C	POLD1	c.3122T>C	p.V1041A	Missense	26/27	-
19-50920352-G-C	POLD1	c.3118G>C	p.E1040Q	Missense	25/27	-
19-50920353-A-C	POLD1	c.3119A>C	p.E1040A	Missense	25/27	-
19-50921182-C-T	POLD1	c.3302C>T	p.P1101L	Missense	27/27	-
X-47426466-C-A	ARAF	c.809C>A	p.P270Q	Missense	9/16	-
7-140476855-C-T	BRAF	c.1551G>A	p.M517I	Missense	13/18	-
7-140477852-T-C	BRAF	c.1456A>G	p.N486D	Missense	12/18	-
19-41743997-G-T	AXL	c.932G>T	p.C311F	Missense	7/20	-
7-140549992-C-T	BRAF	c.159G>A	p.M53I	Missense	2/18	-
7-140476855-C-G	BRAF	c.1551G>C	p.M517I	Missense	13/18	-
7-140476881-G-C	BRAF	c.1525C>G	p.R509G	Missense	13/18	-
7-140494227-G-A	BRAF	c.1021C>T	p.P341S	Missense	8/18	-
7-140508737-C-G	BRAF	c.563G>C	p.R188T	Missense	4/18	-
7-55270223-C-G	EGFR	c.3176C>G	p.P1059R	Missense	27/28	-
7-55229232-G-C	EGFR	c.1539G>C	p.E513D	Missense	13/28	-
7-55270307-T-C	EGFR	c.3260T>C	p.L1087P	Missense	27/28	-
7-55270263-C-G	EGFR	c.3216C>G	p.D1072E	Missense	27/28	-
17-37879851-A-G	ERBB2	c.2146A>G	p.K716E	Missense	18/27	-
17-37872096-C-A	ERBB2	c.1417C>A	p.H473N	Missense	12/27	-
17-37868701-G-A	ERBB2	c.1148G>A	p.G383E	Missense	9/27	-
17-37881015-G-A	ERBB2	c.2344G>A	p.V782I	Missense	20/27	-
17-37879580-C-G	ERBB2	c.1955C>G	p.T652R	Missense	17/27	-
17-37872834-T-G	ERBB2	c.1713T>G	p.N571K	Missense	14/27	-
17-37872834-T-A	ERBB2	c.1713T>A	p.N571K	Missense	14/27	-
17-37883959-G-T	ERBB2	c.3430G>T	p.D1144Y	Missense	27/27	-
17-37871725-G-T	ERBB2	c.1249G>T	p.D417Y	Missense	11/27	-
17-37883140-G-T	ERBB2	c.3043G>T	p.G1015W	Missense	25/27	-
17-37871562-C-A	ERBB2	c.1172C>A	p.P391Q	Missense	10/27	-
15-99491930-G-C	IGF1R	c.3715G>C	p.D1239H	Missense	20/21	-
13-28919604-A-G	FLT1	c.2333T>C	p.L778P	Missense	16/30	-
7-116371822-T-G	MET	c.1301T>G	p.F434C	Missense	3/21	-
13-28964128-G-T	FLT1	c.1774C>A	p.L592M	Missense	13/30	-
13-28903802-C-A	FLT1	c.2657G>T	p.G886V	Missense	19/30	-
7-116380068-T-C	MET	c.1457T>C	p.V486A	Missense	4/21	-
4-1808921-G-A	FGFR3	c.2353G>A	p.D785N	Missense	18/18	-
10-123274744-C-T	FGFR2	c.1174G>A	p.V392M	Missense	9/18	-
15-99478265-T-C	IGF1R	c.3169T>C	p.F1057L	Missense	16/21	-
15-99478267-C-A	IGF1R	c.3171C>A	p.F1057L	Missense	16/21	-
15-99478267-C-G	IGF1R	c.3171C>G	p.F1057L	Missense	16/21	-
4-1806149-G-A	FGFR3	c.1168G>A	p.V390M	Missense	9/18	-
15-99459279-G-C	IGF1R	c.1915G>C	p.G639R	Missense	9/21	-
8-38282092-T-C	FGFR1	c.871A>G	p.K291E	Missense	7/18	-
10-123239442-A-C	FGFR2	c.2395T>G	p.S799A	Missense	18/18	-
8-38271773-T-C	FGFR1	c.2083A>G	p.T695A	Missense	16/18	-
15-99440011-C-T	IGF1R	c.979C>T	p.P327S	Missense	4/21	-
8-38275797-A-G	FGFR1	c.1379T>C	p.V460A	Missense	10/18	-
17-41276047-C-T	BRCA1	c.67G>A	p.E23K	Missense	2/23	-
19-50921188-G-C	POLD1	c.3308G>C	p.G1103A	Missense	27/27	-
19-50921185-C-T	POLD1	c.3305C>T	p.P1102L	Missense	27/27	-
19-50921162-G-T	POLD1	c.3282G>T	p.Q1094H	Missense	27/27	-
3-178916684-G-A	PIK3CA	c.71G>A	p.C24Y	Missense	2/21	-
3-178947853-A-G	PIK3CA	c.2728A>G	p.I910V	Missense	19/21	-
3-12660029-G-T	RAF1	c.192C>A	p.N64K	Missense	2/17	-
1-9784049-G-A	PIK3CD	c.2617G>A	p.E873K	Missense	21/24	-
9-98211520-C-T	PTCH1	c.3635G>A	p.G1212D	Missense	22/24	-
3-138453637-T-C	PIK3CB	c.811A>G	p.N271D	Missense	7/24	-
3-138413677-G-C	PIK3CB	c.1843C>G	p.P615A	Missense	14/24	-
3-138400833-C-A	PIK3CB	c.2480G>T	p.W827L	Missense	19/24	-
5-67590404-A-G	PIK3R1	c.1466A>G	p.E489G	Missense	12/16	-
3-12660029-G-C	RAF1	c.192C>G	p.N64K	Missense	2/17	-
3-12626094-C-G	RAF1	c.1866G>C	p.E622D	Missense	17/17	-
3-12626094-C-A	RAF1	c.1866G>T	p.E622D	Missense	17/17	-
3-12650343-C-T	RAF1	c.503G>A	p.C168Y	Missense	5/17	-
7-128846076-A-C	SMO	c.1006A>C	p.T336P	Missense	5/12	-
3-30713327-A-G	TGFBR2	c.652A>G	p.I218V	Missense	4/7	-
3-12632328-C-T	RAF1	c.1339G>A	p.D447N	Missense	12/17	-
3-12629110-T-C	RAF1	c.1397A>G	p.H466R	Missense	13/17	-
3-12650749-G-T	RAF1	c.406C>A	p.L136I	Missense	4/17	-
3-12632392-C-G	RAF1	c.1275G>C	p.E425D	Missense	12/17	-
3-12632392-C-A	RAF1	c.1275G>T	p.E425D	Missense	12/17	-
7-128850317-G-A	SMO	c.1580G>A	p.G527E	Missense	9/12	-
7-128846053-G-T	SMO	c.983G>T	p.G328V	Missense	5/12	-
19-41850681-C-T	TGFB1	c.605G>A	p.G202E	Missense	3/7	-
3-12626417-G-A	RAF1	c.1732C>T	p.P578S	Missense	16/17	-
7-128851512-G-A	SMO	c.1837G>A	p.D613N	Missense	11/12	-
3-12626468-C-G	RAF1	c.1681G>C	p.V561L	Missense	16/17	-
3-12626468-C-A	RAF1	c.1681G>T	p.V561L	Missense	16/17	-
7-128845167-C-T	SMO	c.661C>T	p.L221F	Missense	3/12	-
17-7578236-A-C	TP53	c.613T>G	p.Y205D	Missense	6/11	-
17-41245471-C-T	BRCA1	c.2077G>A	p.D693N	Missense	10/23	-
17-41222975-C-T	BRCA1	c.4956G>A	p.M1652I	Missense	15/23	-
17-41245027-G-A	BRCA1	c.2521C>T	p.R841W	Missense	10/23	-
13-32893271-A-G	BRCA2	c.125A>G	p.Y42C	Missense	3/27	-
17-7579412-G-A	TP53	c.275C>T	p.P92L	Missense	4/11	-
7-55233037-C-T	EGFR	c.1787C>T	p.P596L	Missense	15/28	-
7-55221743-A-C	EGFR	c.787A>C	p.T263P	Missense	7/28	-
17-41215385-T-C	BRCA1	c.5158A>G	p.T1720A	Missense	18/23	-
7-55259517-G-A	EGFR	c.2575G>A	p.A859T	Missense	21/28	-
7-55259485-C-T	EGFR	c.2543C>T	p.P848L	Missense	21/28	-
17-7576924-G-C	TP53	c.922C>G	p.L308V	Missense	9/11	-
7-140481417-C-T	BRAF	c.1391G>A	p.G464E	Missense	11/18	-
17-41245233-A-G	BRCA1	c.2315T>C	p.V772A	Missense	10/23	-
13-32972884-A-G	BRCA2	c.10234A>G	p.I3412V	Missense	27/27	-
17-41249283-C-T	BRCA1	c.571G>A	p.V191I	Missense	8/23	-
17-7576903-A-C	TP53	c.943T>G	p.S315A	Missense	9/11	-
12-112888202-C-T	PTPN11	c.218C>T	p.T73I	Missense	3/16	-
17-41267760-A-C	BRCA1	c.117T>G	p.C39W	Missense	3/23	-
17-41246062-G-A	BRCA1	c.1486C>T	p.R496C	Missense	10/23	-
17-7579578-A-C	TP53	c.109T>G	p.S37A	Missense	4/11	-
17-7577524-T-C	TP53	c.757A>G	p.T253A	Missense	7/11	-
17-41223048-A-G	BRCA1	c.4883T>C	p.M1628T	Missense	15/23	-
17-41199716-A-T	BRCA1	c.5411T>A	p.V1804D	Missense	22/23	-
17-7577098-T-A	TP53	c.840A>T	p.R280S	Missense	8/11	-
17-7578271-T-G	TP53	c.578A>C	p.H193P	Missense	6/11	-
13-32953550-G-A	BRCA2	c.8851G>A	p.A2951T	Missense	22/27	-
17-7578415-A-T	TP53	c.515T>A	p.V172D	Missense	5/11	-
17-7577084-T-A	TP53	c.854A>T	p.E285V	Missense	8/11	-
7-55249022-G-C	EGFR	c.2320G>C	p.V774L	Missense	20/28	-
17-7577550-C-G	TP53	c.731G>C	p.G244A	Missense	7/11	-
17-7577511-A-G	TP53	c.770T>C	p.L257P	Missense	7/11	-
17-7578235-T-A	TP53	c.614A>T	p.Y205F	Missense	6/11	-
7-55249022-G-T	EGFR	c.2320G>T	p.V774L	Missense	20/28	-
17-7578464-G-A	TP53	c.466C>T	p.R156C	Missense	5/11	-
17-7576896-T-C	TP53	c.950A>G	p.Q317R	Missense	9/11	-
17-7577526-A-G	TP53	c.755T>C	p.L252P	Missense	7/11	-
17-7578527-A-G	TP53	c.403T>C	p.C135R	Missense	5/11	-
17-7578515-T-G	TP53	c.415A>C	p.K139Q	Missense	5/11	-
17-7578250-T-C	TP53	c.599A>G	p.N200S	Missense	6/11	-
17-7578461-C-G	TP53	c.469G>C	p.V157L	Missense	5/11	-
17-7578212-G-C	TP53	c.637C>G	p.R213G	Missense	6/11	-
17-7577598-T-C	TP53	c.683A>G	p.D228G	Missense	7/11	-
17-7578227-C-T	TP53	c.622G>A	p.D208N	Missense	6/11	-
17-7578467-T-C	TP53	c.463A>G	p.T155A	Missense	5/11	-
17-7577037-G-A	TP53	c.901C>T	p.P301S	Missense	8/11	-
17-37881440-C-T	ERBB2	c.2632C>T	p.H878Y	Missense	21/27	-
17-7578490-A-C	TP53	c.440T>G	p.V147G	Missense	5/11	-
17-7578281-G-A	TP53	c.568C>T	p.P190S	Missense	6/11	-
17-7577088-T-G	TP53	c.850A>C	p.T284P	Missense	8/11	-
7-55211050-G-A	EGFR	c.293G>A	p.R98Q	Missense	3/28	-
4-55141036-T-A	PDGFRA	c.1682T>A	p.V561D	Missense	12/23	-
7-55233121-G-T	EGFR	c.1871G>T	p.C624F	Missense	15/28	-
13-32914236-C-T	BRCA2	c.5744C>T	p.T1915M	Missense	11/27	-
12-25362838-T-A	KRAS	c.458A>T	p.D153V	Missense	5/5	-
12-25398218-G-C	KRAS	c.101C>G	p.P34R	Missense	2/5	-
17-41258495-A-C	BRCA1	c.190T>G	p.C64G	Missense	4/23	-
7-55241678-A-G	EGFR	c.2126A>G	p.E709G	Missense	18/28	-
7-55259530-G-A	EGFR	c.2588G>A	p.G863D	Missense	21/28	-
17-7577566-T-A	TP53	c.715A>T	p.N239Y	Missense	7/11	-
17-7578533-T-G	TP53	c.397A>C	p.M133L	Missense	5/11	-
17-7578533-T-A	TP53	c.397A>T	p.M133L	Missense	5/11	-
17-7578486-A-C	TP53	c.444T>G	p.D148E	Missense	5/11	-
17-7577529-A-C	TP53	c.752T>G	p.I251S	Missense	7/11	-
17-7579350-A-C	TP53	c.337T>G	p.F113V	Missense	4/11	-
17-7577560-A-C	TP53	c.721T>G	p.S241A	Missense	7/11	-
13-32906766-C-T	BRCA2	c.1151C>T	p.S384F	Missense	10/27	-
13-32945172-A-C	BRCA2	c.8567A>C	p.E2856A	Missense	20/27	-
13-32911295-G-A	BRCA2	c.2803G>A	p.D935N	Missense	11/27	-
17-37880989-T-C	ERBB2	c.2318T>C	p.V773A	Missense	20/27	-
17-7577574-T-A	TP53	c.707A>T	p.Y236F	Missense	7/11	-
17-41243509-T-C	BRCA1	c.4039A>G	p.R1347G	Missense	10/23	-
17-7579855-A-C	TP53	c.58T>G	p.S20A	Missense	2/11	-
17-7572977-A-C	TP53	c.1132T>G	p.S378A	Missense	11/11	-
17-7572935-A-C	TP53	c.1174T>G	p.S392A	Missense	11/11	-
17-41256155-G-T	BRCA1	c.425C>A	p.P142H	Missense	6/23	-
17-41244524-C-T	BRCA1	c.3024G>A	p.M1008I	Missense	10/23	-
10-123310871-A-G	FGFR2	c.557T>C	p.M186T	Missense	5/18	-
3-178916946-G-T	PIK3CA	c.333G>T	p.K111N	Missense	2/21	-
4-55592202-A-T	KIT	c.1526A>T	p.K509I	Missense	9/21	-
13-32937521-G-A	BRCA2	c.8182G>A	p.V2728I	Missense	18/27	-
13-32911452-A-T	BRCA2	c.2960A>T	p.N987I	Missense	11/27	-
13-32911278-T-C	BRCA2	c.2786T>C	p.L929S	Missense	11/27	-
13-32912750-G-T	BRCA2	c.4258G>T	p.D1420Y	Missense	11/27	-
13-32912733-C-T	BRCA2	c.4241C>T	p.T1414M	Missense	11/27	-
13-32953971-C-T	BRCA2	c.9038C>T	p.T3013I	Missense	23/27	-
13-32913077-G-A	BRCA2	c.4585G>A	p.G1529R	Missense	11/27	-
13-32913077-G-C	BRCA2	c.4585G>C	p.G1529R	Missense	11/27	-
13-32914839-A-G	BRCA2	c.6347A>G	p.H2116R	Missense	11/27	-
13-32937488-G-T	BRCA2	c.8149G>T	p.A2717S	Missense	18/27	-
17-41246411-A-C	BRCA1	c.1137T>G	p.I379M	Missense	10/23	-
13-32912361-G-A	BRCA2	c.3869G>A	p.C1290Y	Missense	11/27	-
13-32907401-G-C	BRCA2	c.1786G>C	p.D596H	Missense	10/27	-
17-41243948-C-A	BRCA1	c.3600G>T	p.Q1200H	Missense	10/23	-
17-41243948-C-G	BRCA1	c.3600G>C	p.Q1200H	Missense	10/23	-
13-32907407-A-G	BRCA2	c.1792A>G	p.T598A	Missense	10/27	-
13-32945108-T-C	BRCA2	c.8503T>C	p.S2835P	Missense	20/27	-
17-41245900-T-G	BRCA1	c.1648A>C	p.N550H	Missense	10/23	-
13-32906593-C-G	BRCA2	c.978C>G	p.S326R	Missense	10/27	-
13-32906593-C-A	BRCA2	c.978C>A	p.S326R	Missense	10/27	-
13-32906591-A-C	BRCA2	c.976A>C	p.S326R	Missense	10/27	-
13-32911547-C-G	BRCA2	c.3055C>G	p.L1019V	Missense	11/27	-
13-32912679-A-G	BRCA2	c.4187A>G	p.Q1396R	Missense	11/27	-
17-41244246-C-T	BRCA1	c.3302G>A	p.S1101N	Missense	10/23	-
17-41244130-T-C	BRCA1	c.3418A>G	p.S1140G	Missense	10/23	-
17-41223249-G-A	BRCA1	c.4682C>T	p.T1561I	Missense	15/23	-
17-41243940-C-T	BRCA1	c.3608G>A	p.R1203Q	Missense	10/23	-
17-41244429-C-T	BRCA1	c.3119G>A	p.S1040N	Missense	10/23	-
17-41243835-G-A	BRCA1	c.3713C>T	p.P1238L	Missense	10/23	-
13-32913690-C-T	BRCA2	c.5198C>T	p.S1733F	Missense	11/27	-
17-41226488-C-A	BRCA1	c.4535G>T	p.S1512I	Missense	14/23	-
17-41245090-T-C	BRCA1	c.2458A>G	p.K820E	Missense	10/23	-
17-41226423-C-T	BRCA1	c.4600G>A	p.V1534M	Missense	14/23	-
17-41258506-T-C	BRCA1	c.179A>G	p.Q60R	Missense	4/23	-
13-32910456-C-G	BRCA2	c.1964C>G	p.P655R	Missense	11/27	-
17-41246812-A-C	BRCA1	c.736T>G	p.L246V	Missense	10/23	-
13-32907000-A-G	BRCA2	c.1385A>G	p.E462G	Missense	10/27	-
13-32929309-A-G	BRCA2	c.7319A>G	p.H2440R	Missense	14/27	-
17-41245381-T-C	BRCA1	c.2167A>G	p.N723D	Missense	10/23	-
13-32929140-C-A	BRCA2	c.7150C>A	p.Q2384K	Missense	14/27	-
13-32907419-G-A	BRCA2	c.1804G>A	p.G602R	Missense	10/27	-
13-32907419-G-C	BRCA2	c.1804G>C	p.G602R	Missense	10/27	-
17-41246092-A-G	BRCA1	c.1456T>C	p.F486L	Missense	10/23	-
17-41246090-A-T	BRCA1	c.1458T>A	p.F486L	Missense	10/23	-
17-41246090-A-C	BRCA1	c.1458T>G	p.F486L	Missense	10/23	-
13-32914815-G-A	BRCA2	c.6323G>A	p.R2108H	Missense	11/27	-
13-32914592-C-T	BRCA2	c.6100C>T	p.R2034C	Missense	11/27	-
17-41246061-C-T	BRCA1	c.1487G>A	p.R496H	Missense	10/23	-
7-55259545-A-G	EGFR	c.2603A>G	p.E868G	Missense	21/28	-
13-32930592-G-A	BRCA2	c.7463G>A	p.R2488K	Missense	15/27	-
3-178936083-A-T	PIK3CA	c.1625A>T	p.E542V	Missense	10/21	-
17-7573931-A-C	TP53	c.1096T>G	p.S366A	Missense	10/11	-
13-32937507-A-G	BRCA2	c.8168A>G	p.D2723G	Missense	18/27	-
13-32937333-A-G	BRCA2	c.7994A>G	p.D2665G	Missense	18/27	-
15-66774188-T-G	MAP2K1	c.664T>G	p.S222A	Missense	6/11	-
4-55602694-G-A	KIT	c.2515G>A	p.E839K	Missense	18/21	-
4-55593610-T-G	KIT	c.1676T>G	p.V559G	Missense	11/21	-
17-41246037-C-T	BRCA1	c.1511G>A	p.R504H	Missense	10/23	-
13-32914277-A-G	BRCA2	c.5785A>G	p.I1929V	Missense	11/27	-
17-41244982-A-G	BRCA1	c.2566T>C	p.Y856H	Missense	10/23	-
13-32913804-G-A	BRCA2	c.5312G>A	p.G1771D	Missense	11/27	-
17-7577069-C-T	TP53	c.869G>A	p.R290H	Missense	8/11	-
17-41276043-C-T	BRCA1	c.71G>A	p.C24Y	Missense	2/23	-
17-41267762-A-G	BRCA1	c.115T>C	p.C39R	Missense	3/23	-
17-41258494-C-T	BRCA1	c.191G>A	p.C64Y	Missense	4/23	-
13-32893369-G-C	BRCA2	c.223G>C	p.A75P	Missense	3/27	-
11-69466021-C-T	CCND1	c.859C>T	p.P287S	Missense	5/5	-
7-55260483-G-A	EGFR	c.2650G>A	p.E884K	Missense	22/28	-
17-7578427-T-G	TP53	c.503A>C	p.H168P	Missense	5/11	-
17-37880998-G-T	ERBB2	c.2327G>T	p.G776V	Missense	20/27	-
7-140453139-G-A	BRAF	c.1796C>T	p.T599I	Missense	15/18	-
10-123298174-C-T	FGFR2	c.680G>A	p.G227E	Missense	6/18	-
17-7579885-C-G	TP53	c.28G>C	p.V10L	Missense	2/11	-
17-7579864-C-T	TP53	c.49G>A	p.E17K	Missense	2/11	-
17-7578226-T-G	TP53	c.623A>C	p.D208A	Missense	6/11	-
17-41258504-A-G	BRCA1	c.181T>C	p.C61R	Missense	4/23	-
17-7576911-G-A	TP53	c.935C>T	p.T312I	Missense	9/11	-
17-7577107-A-C	TP53	c.831T>G	p.C277W	Missense	8/11	-
17-41249297-G-T	BRCA1	c.557C>A	p.S186Y	Missense	8/23	-
17-41245071-G-T	BRCA1	c.2477C>A	p.T826K	Missense	10/23	-
17-7578460-A-T	TP53	c.470T>A	p.V157D	Missense	5/11	-
17-7577557-A-G	TP53	c.724T>C	p.C242R	Missense	7/11	-
17-7578551-A-G	TP53	c.379T>C	p.S127P	Missense	5/11	-
17-7578472-G-A	TP53	c.458C>T	p.P153L	Missense	5/11	-
17-41276061-A-G	BRCA1	c.53T>C	p.M18T	Missense	2/23	-
17-7579551-A-C	TP53	c.136T>G	p.S46A	Missense	4/11	-
7-140477861-T-C	BRAF	c.1447A>G	p.K483E	Missense	12/18	-
7-140453152-A-G	BRAF	c.1783T>C	p.F595L	Missense	15/18	-
7-140453150-A-T	BRAF	c.1785T>A	p.F595L	Missense	15/18	-
7-140453150-A-C	BRAF	c.1785T>G	p.F595L	Missense	15/18	-
7-140453154-T-A	BRAF	c.1781A>T	p.D594V	Missense	15/18	-
17-7578391-T-C	TP53	c.539A>G	p.E180G	Missense	5/11	-
17-7577503-A-C	TP53	c.778T>G	p.S260A	Missense	7/11	-
17-7578281-G-C	TP53	c.568C>G	p.P190A	Missense	6/11	-
17-41276046-T-A	BRCA1	c.68A>T	p.E23V	Missense	2/23	-
17-7573996-A-G	TP53	c.1031T>C	p.L344P	Missense	10/11	-
17-7578272-G-T	TP53	c.577C>A	p.H193N	Missense	6/11	-
3-178936103-G-A	PIK3CA	c.1645G>A	p.D549N	Missense	10/21	-
17-7577543-C-G	TP53	c.738G>C	p.M246I	Missense	7/11	-
17-7578518-C-G	TP53	c.412G>C	p.A138P	Missense	5/11	-
17-7577553-A-G	TP53	c.728T>C	p.M243T	Missense	7/11	-
17-7578274-T-C	TP53	c.575A>G	p.Q192R	Missense	6/11	-
17-7577545-T-G	TP53	c.736A>C	p.M246L	Missense	7/11	-
17-7577545-T-A	TP53	c.736A>T	p.M246L	Missense	7/11	-
17-7577543-C-A	TP53	c.738G>T	p.M246I	Missense	7/11	-
17-7577112-C-T	TP53	c.826G>A	p.A276T	Missense	8/11	-
17-7579320-T-C	TP53	c.367A>G	p.T123A	Missense	4/11	-
17-7577114-C-G	TP53	c.824G>C	p.C275S	Missense	8/11	-
17-7578225-G-C	TP53	c.624C>G	p.D208E	Missense	6/11	-
17-7578225-G-T	TP53	c.624C>A	p.D208E	Missense	6/11	-
17-7577577-T-A	TP53	c.704A>T	p.N235I	Missense	7/11	-
17-7578443-A-C	TP53	c.487T>G	p.Y163D	Missense	5/11	-
7-140453092-C-T	BRAF	c.1843G>A	p.G615R	Missense	15/18	-
7-140453092-C-G	BRAF	c.1843G>C	p.G615R	Missense	15/18	-
17-7573974-C-G	TP53	c.1053G>C	p.K351N	Missense	10/11	-
17-7573974-C-A	TP53	c.1053G>T	p.K351N	Missense	10/11	-
17-7579368-A-C	TP53	c.319T>G	p.Y107D	Missense	4/11	-
17-7577569-A-C	TP53	c.712T>G	p.C238G	Missense	7/11	-
17-7577511-A-T	TP53	c.770T>A	p.L257Q	Missense	7/11	-
17-7578196-A-C	TP53	c.653T>G	p.V218G	Missense	6/11	-
17-7578397-T-G	TP53	c.533A>C	p.H178P	Missense	5/11	-
7-55259553-G-A	EGFR	c.2611G>A	p.A871T	Missense	21/28	-
13-32915313-G-T	BRCA2	c.6821G>T	p.G2274V	Missense	11/27	-
3-178947827-G-T	PIK3CA	c.2702G>T	p.C901F	Missense	19/21	-
3-178938860-A-C	PIK3CA	c.2102A>C	p.H701P	Missense	14/21	-
7-140481418-C-G	BRAF	c.1390G>C	p.G464R	Missense	11/18	-
7-140481412-C-T	BRAF	c.1396G>A	p.G466R	Missense	11/18	-
7-140481412-C-G	BRAF	c.1396G>C	p.G466R	Missense	11/18	-
17-41215899-C-T	BRCA1	c.5144G>A	p.S1715N	Missense	17/23	-
17-7579359-G-C	TP53	c.328C>G	p.R110G	Missense	4/11	-
17-7577117-A-C	TP53	c.821T>G	p.V274G	Missense	8/11	-
4-1806133-C-A	FGFR3	c.1152C>A	p.F384L	Missense	9/18	-
2-29416366-G-C	ALK	c.4587C>G	p.D1529E	Missense	29/29	-
2-29416481-T-C	ALK	c.4472A>G	p.K1491R	Missense	29/29	-
7-140453154-T-G	BRAF	c.1781A>C	p.D594A	Missense	15/18	-
3-178952142-C-T	PIK3CA	c.3197C>T	p.A1066V	Missense	21/21	-
3-178917496-C-T	PIK3CA	c.371C>T	p.P124L	Missense	3/21	-
3-178937753-A-G	PIK3CA	c.1928A>G	p.Q643R	Missense	13/21	-
3-178951994-G-C	PIK3CA	c.3049G>C	p.D1017H	Missense	21/21	-
7-55242455-T-C	EGFR	c.2225T>C	p.V742A	Missense	19/28	-
4-1806131-T-C	FGFR3	c.1150T>C	p.F384L	Missense	9/18	-
4-55599341-T-G	KIT	c.2467T>G	p.Y823D	Missense	17/21	-
17-7578272-G-C	TP53	c.577C>G	p.H193D	Missense	6/11	-
4-1806133-C-G	FGFR3	c.1152C>G	p.F384L	Missense	9/18	-
4-55593603-T-G	KIT	c.1669T>G	p.W557G	Missense	11/21	-
4-55593431-G-A	KIT	c.1588G>A	p.V530I	Missense	10/21	-
3-12650355-C-T	RAF1	c.491G>A	p.R164Q	Missense	5/17	-
4-55133820-C-T	PDGFRA	c.1033C>T	p.P345S	Missense	7/23	-
7-55220274-C-T	EGFR	c.664C>T	p.R222C	Missense	6/28	-
7-55220295-A-T	EGFR	c.685A>T	p.S229C	Missense	6/28	-
7-55224307-C-T	EGFR	c.1088C>T	p.T363I	Missense	9/28	-
10-89692922-T-C	PTEN	c.406T>C	p.C136R	Missense	5/9	-
7-55221722-G-T	EGFR	c.766G>T	p.D256Y	Missense	7/28	-
17-7577130-A-G	TP53	c.808T>C	p.F270L	Missense	8/11	-
17-7577128-A-T	TP53	c.810T>A	p.F270L	Missense	8/11	-
17-7578376-C-T	TP53	c.554G>A	p.S185N	Missense	5/11	-
17-7577128-A-C	TP53	c.810T>G	p.F270L	Missense	8/11	-
17-7578427-T-A	TP53	c.503A>T	p.H168L	Missense	5/11	-
17-7578476-G-T	TP53	c.454C>A	p.P152T	Missense	5/11	-
17-7577129-A-G	TP53	c.809T>C	p.F270S	Missense	8/11	-
17-7577144-A-C	TP53	c.794T>G	p.L265R	Missense	8/11	-
17-7577118-C-G	TP53	c.820G>C	p.V274L	Missense	8/11	-
17-7579328-T-A	TP53	c.359A>T	p.K120M	Missense	4/11	-
17-7578268-A-G	TP53	c.581T>C	p.L194P	Missense	6/11	-
10-123274746-A-C	FGFR2	c.1172T>G	p.M391R	Missense	9/18	-
10-123274738-T-C	FGFR2	c.1180A>G	p.T394A	Missense	9/18	-
10-123274773-C-T	FGFR2	c.1145G>A	p.C382Y	Missense	9/18	-
10-123279522-C-T	FGFR2	c.910G>A	p.D304N	Missense	7/18	-
10-123279660-G-A	FGFR2	c.772C>T	p.L258F	Missense	7/18	-
4-1801241-C-T	FGFR3	c.370C>T	p.R124W	Missense	3/18	-
4-1801019-G-A	FGFR3	c.148G>A	p.V50I	Missense	3/18	-
4-1801486-C-T	FGFR3	c.392C>T	p.S131L	Missense	4/18	-
4-1803162-G-A	FGFR3	c.514G>A	p.V172I	Missense	5/18	-
4-1803208-C-A	FGFR3	c.560C>A	p.S187Y	Missense	5/18	-
8-38271301-G-A	FGFR1	c.2314C>T	p.P772S	Missense	18/18	-
4-1805540-C-G	FGFR3	c.1052C>G	p.S351C	Missense	8/18	-
4-1803642-C-T	FGFR3	c.820C>T	p.H274Y	Missense	7/18	-
4-1806059-G-C	FGFR3	c.1078G>C	p.E360Q	Missense	9/18	-
4-1806153-C-T	FGFR3	c.1172C>T	p.A391V	Missense	9/18	-
4-1806162-C-T	FGFR3	c.1181C>T	p.T394M	Missense	9/18	-
4-1806176-C-T	FGFR3	c.1195C>T	p.R399C	Missense	9/18	-
4-1806638-G-T	FGFR3	c.1354G>T	p.A452S	Missense	10/18	-
8-38277065-G-A	FGFR1	c.1270C>T	p.R424C	Missense	9/18	-
8-38279318-C-T	FGFR1	c.1078G>A	p.E360K	Missense	8/18	-
8-38283759-C-T	FGFR1	c.626G>A	p.R209H	Missense	6/18	-
4-1807865-G-A	FGFR3	c.1924G>A	p.V642M	Missense	14/18	-
8-38282146-C-T	FGFR1	c.817G>A	p.V273M	Missense	7/18	-
8-38282215-G-A	FGFR1	c.748C>T	p.R250W	Missense	7/18	-
4-1808907-C-G	FGFR3	c.2339C>G	p.S780C	Missense	18/18	-
4-1808930-G-A	FGFR3	c.2362G>A	p.V788M	Missense	18/18	-
4-1808924-G-A	FGFR3	c.2356G>A	p.D786N	Missense	18/18	-
10-123244913-C-T	FGFR2	c.2191G>A	p.E731K	Missense	16/18	-
4-1808982-G-A	FGFR3	c.2414G>A	p.R805Q	Missense	18/18	-
7-116339642-G-T	MET	c.504G>T	p.E168D	Missense	2/21	-
17-41276051-G-C	BRCA1	c.63C>G	p.I21M	Missense	2/23	-
7-116340189-C-G	MET	c.1051C>G	p.P351A	Missense	2/21	-
7-116340237-A-G	MET	c.1099A>G	p.I367V	Missense	2/21	-
7-116371758-C-G	MET	c.1237C>G	p.R413G	Missense	3/21	-
17-41267779-T-G	BRCA1	c.98A>C	p.E33A	Missense	3/23	-
17-7578244-C-T	TP53	c.605G>A	p.R202H	Missense	6/11	-
7-55249028-C-T	EGFR	c.2326C>T	p.R776C	Missense	20/28	-
7-55259433-C-T	EGFR	c.2491C>T	p.R831C	Missense	21/28	-
17-7578196-A-G	TP53	c.653T>C	p.V218A	Missense	6/11	-
17-7579448-G-A	TP53	c.239C>T	p.P80L	Missense	4/11	-
17-7577517-A-G	TP53	c.764T>C	p.I255T	Missense	7/11	-
17-7579557-T-C	TP53	c.130A>G	p.M44V	Missense	4/11	-
3-178937422-T-C	PIK3CA	c.1810T>C	p.C604R	Missense	12/21	-
17-7578550-G-T	TP53	c.380C>A	p.S127Y	Missense	5/11	-
17-7578226-T-A	TP53	c.623A>T	p.D208V	Missense	6/11	-
7-128845128-G-A	SMO	c.622G>A	p.E208K	Missense	3/12	-
17-37868216-C-G	ERBB2	c.937C>G	p.L313V	Missense	8/27	-
17-7577548-C-G	TP53	c.733G>C	p.G245R	Missense	7/11	-
3-178952054-G-A	PIK3CA	c.3109G>A	p.E1037K	Missense	21/21	-
17-7577547-C-G	TP53	c.734G>C	p.G245A	Missense	7/11	-
12-112891083-G-C	PTPN11	c.417G>C	p.E139D	Missense	4/16	-
17-7576921-G-A	TP53	c.925C>T	p.P309S	Missense	9/11	-
17-7577550-C-A	TP53	c.731G>T	p.G244V	Missense	7/11	-
17-7579571-G-A	TP53	c.116C>T	p.A39V	Missense	4/11	-
17-7578554-A-G	TP53	c.376T>C	p.Y126H	Missense	5/11	-
17-7579356-G-T	TP53	c.331C>A	p.L111M	Missense	4/11	-
17-7579373-C-A	TP53	c.314G>T	p.G105V	Missense	4/11	-
17-7578538-T-A	TP53	c.392A>T	p.N131I	Missense	5/11	-
17-7578524-G-C	TP53	c.406C>G	p.Q136E	Missense	5/11	-
17-7578398-G-C	TP53	c.532C>G	p.H178D	Missense	5/11	-
17-7578522-T-A	TP53	c.408A>T	p.Q136H	Missense	5/11	-
17-7578442-T-G	TP53	c.488A>C	p.Y163S	Missense	5/11	-
17-7577580-T-G	TP53	c.701A>C	p.Y234S	Missense	7/11	-
17-7577565-T-A	TP53	c.716A>T	p.N239I	Missense	7/11	-
17-7578514-T-G	TP53	c.416A>C	p.K139T	Missense	5/11	-
17-7577108-C-T	TP53	c.830G>A	p.C277Y	Missense	8/11	-
17-7577593-T-C	TP53	c.688A>G	p.T230A	Missense	7/11	-
10-89624261-A-C	PTEN	c.35A>C	p.N12T	Missense	1/9	-
17-7577535-C-T	TP53	c.746G>A	p.R249K	Missense	7/11	-
17-7579329-T-C	TP53	c.358A>G	p.K120E	Missense	4/11	-
17-7577567-A-C	TP53	c.714T>G	p.C238W	Missense	7/11	-
7-55259538-G-A	EGFR	c.2596G>A	p.E866K	Missense	21/28	-
3-178921566-G-A	PIK3CA	c.1048G>A	p.D350N	Missense	5/21	-
17-7577569-A-T	TP53	c.712T>A	p.C238S	Missense	7/11	-
17-7579434-G-A	TP53	c.253C>T	p.P85S	Missense	4/11	-
17-7579349-A-C	TP53	c.338T>G	p.F113C	Missense	4/11	-
17-7579866-T-A	TP53	c.47A>T	p.Q16L	Missense	2/11	-
17-7578496-A-G	TP53	c.434T>C	p.L145P	Missense	5/11	-
3-178952072-A-T	PIK3CA	c.3127A>T	p.M1043L	Missense	21/21	-
17-7577560-A-T	TP53	c.721T>A	p.S241T	Missense	7/11	-
17-7574027-C-A	TP53	c.1000G>T	p.G334W	Missense	10/11	-
17-7578388-C-G	TP53	c.542G>C	p.R181P	Missense	5/11	-
17-41276056-T-G	BRCA1	c.58A>C	p.K20Q	Missense	2/23	-
17-41276055-T-C	BRCA1	c.59A>G	p.K20R	Missense	2/23	-
17-7577535-C-G	TP53	c.746G>C	p.R249T	Missense	7/11	-
17-7578244-C-A	TP53	c.605G>T	p.R202L	Missense	6/11	-
17-7578371-C-T	TP53	c.559G>A	p.G187S	Missense	5/11	-
17-7579509-G-C	TP53	c.178C>G	p.P60A	Missense	4/11	-
17-7577575-A-G	TP53	c.706T>C	p.Y236H	Missense	7/11	-
17-7579422-G-A	TP53	c.265C>T	p.P89S	Missense	4/11	-
7-55249007-G-T	EGFR	c.2305G>T	p.V769L	Missense	20/28	-
7-55249007-G-C	EGFR	c.2305G>C	p.V769L	Missense	20/28	-
17-7578443-A-T	TP53	c.487T>A	p.Y163N	Missense	5/11	-
17-7578529-A-C	TP53	c.401T>G	p.F134C	Missense	5/11	-
17-7579361-A-G	TP53	c.326T>C	p.F109S	Missense	4/11	-
17-7577077-C-G	TP53	c.861G>C	p.E287D	Missense	8/11	-
17-7577077-C-A	TP53	c.861G>T	p.E287D	Missense	8/11	-
X-41203370-G-A	DDX3X	c.853G>A	p.E285K	Missense	9/17	-
17-41258503-C-T	BRCA1	c.182G>A	p.C61Y	Missense	4/23	-
17-7578259-A-G	TP53	c.590T>C	p.V197A	Missense	6/11	-
2-29443591-C-T	ALK	c.3626G>A	p.R1209Q	Missense	23/29	-
17-7577085-C-G	TP53	c.853G>C	p.E285Q	Missense	8/11	-
12-25378559-T-C	KRAS	c.439A>G	p.K147E	Missense	4/5	-
17-7577093-C-G	TP53	c.845G>C	p.R282P	Missense	8/11	-
17-7578532-A-T	TP53	c.398T>A	p.M133K	Missense	5/11	-
17-7578487-T-G	TP53	c.443A>C	p.D148A	Missense	5/11	-
3-178936083-A-G	PIK3CA	c.1625A>G	p.E542G	Missense	10/21	-
17-7577129-A-C	TP53	c.809T>G	p.F270C	Missense	8/11	-
17-41223240-A-G	BRCA1	c.4691T>C	p.L1564P	Missense	15/23	-
19-50912834-C-T	POLD1	c.2065C>T	p.R689W	Missense	17/27	-
5-67591106-A-G	PIK3R1	c.1699A>G	p.K567E	Missense	13/16	-
5-67592129-C-T	PIK3R1	c.1945C>T	p.R649W	Missense	15/16	-
12-133237700-T-C	POLE	c.2915A>G	p.E972G	Missense	25/49	-
7-55242511-G-A	EGFR	c.2281G>A	p.D761N	Missense	19/28	-
17-7579369-G-C	TP53	c.318C>G	p.S106R	Missense	4/11	-
17-7578554-A-T	TP53	c.376T>A	p.Y126N	Missense	5/11	-
17-7578227-C-A	TP53	c.622G>T	p.D208Y	Missense	6/11	-
17-7577586-A-T	TP53	c.695T>A	p.I232N	Missense	7/11	-
17-7577581-A-C	TP53	c.700T>G	p.Y234D	Missense	7/11	-
17-7577507-T-G	TP53	c.774A>C	p.E258D	Missense	7/11	-
17-7577096-T-A	TP53	c.842A>T	p.D281V	Missense	8/11	-
17-7577544-A-T	TP53	c.737T>A	p.M246K	Missense	7/11	-
17-7578391-T-G	TP53	c.539A>C	p.E180A	Missense	5/11	-
17-7578406-C-G	TP53	c.524G>C	p.R175P	Missense	5/11	-
17-7578498-C-A	TP53	c.432G>T	p.Q144H	Missense	5/11	-
17-7578498-C-G	TP53	c.432G>C	p.Q144H	Missense	5/11	-
17-7579313-G-C	TP53	c.374C>G	p.T125R	Missense	4/11	-
5-67589138-G-A	PIK3R1	c.1126G>A	p.G376R	Missense	10/16	-
17-7579413-G-C	TP53	c.274C>G	p.P92A	Missense	4/11	-
5-67591097-A-G	PIK3R1	c.1690A>G	p.N564D	Missense	13/16	-
17-7577544-A-C	TP53	c.737T>G	p.M246R	Missense	7/11	-
12-133244133-G-A	POLE	c.2275C>T	p.R759C	Missense	20/49	-
17-7574009-T-C	TP53	c.1018A>G	p.M340V	Missense	10/11	-
3-178921552-A-T	PIK3CA	c.1034A>T	p.N345I	Missense	5/21	-
17-7578439-T-C	TP53	c.491A>G	p.K164R	Missense	5/11	-
1-9779982-T-C	PIK3CD	c.1246T>C	p.C416R	Missense	10/24	-
1-9775907-G-A	PIK3CD	c.371G>A	p.G124D	Missense	5/24	-
17-7577560-A-G	TP53	c.721T>C	p.S241P	Missense	7/11	-
17-7577079-C-T	TP53	c.859G>A	p.E287K	Missense	8/11	-
17-7577123-A-C	TP53	c.815T>G	p.V272G	Missense	8/11	-
17-7578259-A-C	TP53	c.590T>G	p.V197G	Missense	6/11	-
17-7578191-A-T	TP53	c.658T>A	p.Y220N	Missense	6/11	-
17-7578454-G-T	TP53	c.476C>A	p.A159D	Missense	5/11	-
17-7579359-G-A	TP53	c.328C>T	p.R110C	Missense	4/11	-
17-7579499-G-A	TP53	c.188C>T	p.A63V	Missense	4/11	-
17-7578458-G-T	TP53	c.472C>A	p.R158S	Missense	5/11	-
7-55248996-T-G	EGFR	c.2294T>G	p.V765G	Missense	20/28	-
17-41258545-C-A	BRCA1	c.140G>T	p.C47F	Missense	4/23	-
17-41258495-A-G	BRCA1	c.190T>C	p.C64R	Missense	4/23	-
4-55592103-G-T	KIT	c.1427G>T	p.S476I	Missense	9/21	-
3-178916924-C-T	PIK3CA	c.311C>T	p.P104L	Missense	2/21	-
17-7578236-A-T	TP53	c.613T>A	p.Y205N	Missense	6/11	-
17-37868205-G-C	ERBB2	c.926G>C	p.G309A	Missense	8/27	-
17-7573992-A-C	TP53	c.1035T>G	p.N345K	Missense	10/11	-
17-7573992-A-T	TP53	c.1035T>A	p.N345K	Missense	10/11	-
6-152332868-G-A	ESR1	c.1174G>A	p.V392I	Missense	5/8	-
17-7578464-G-C	TP53	c.466C>G	p.R156G	Missense	5/11	-
17-7577533-G-A	TP53	c.748C>T	p.P250S	Missense	7/11	-
17-7577508-T-G	TP53	c.773A>C	p.E258A	Missense	7/11	-
17-7578395-G-C	TP53	c.535C>G	p.H179D	Missense	5/11	-
17-7578429-C-A	TP53	c.501G>T	p.Q167H	Missense	5/11	-
17-7578429-C-G	TP53	c.501G>C	p.Q167H	Missense	5/11	-
3-178936095-A-T	PIK3CA	c.1637A>T	p.Q546L	Missense	10/21	-
3-178916929-G-C	PIK3CA	c.316G>C	p.G106R	Missense	2/21	-
17-7577058-C-G	TP53	c.880G>C	p.E294Q	Missense	8/11	-
17-7577563-T-C	TP53	c.718A>G	p.S240G	Missense	7/11	-
17-7578488-C-G	TP53	c.442G>C	p.D148H	Missense	5/11	-
17-7577517-A-T	TP53	c.764T>A	p.I255N	Missense	7/11	-
2-198267481-T-A	SF3B1	c.1876A>T	p.N626Y	Missense	14/25	-
17-7578551-A-T	TP53	c.379T>A	p.S127T	Missense	5/11	-
17-7578531-C-G	TP53	c.399G>C	p.M133I	Missense	5/11	-
17-7578531-C-T	TP53	c.399G>A	p.M133I	Missense	5/11	-
17-7578531-C-A	TP53	c.399G>T	p.M133I	Missense	5/11	-
17-7578491-C-A	TP53	c.439G>T	p.V147F	Missense	5/11	-
17-7578505-G-A	TP53	c.425C>T	p.P142L	Missense	5/11	-
17-7578404-A-G	TP53	c.526T>C	p.C176R	Missense	5/11	-
17-7577508-T-A	TP53	c.773A>T	p.E258V	Missense	7/11	-
17-7578496-A-C	TP53	c.434T>G	p.L145R	Missense	5/11	-
17-7579358-C-T	TP53	c.329G>A	p.R110H	Missense	4/11	-
17-41245120-T-A	BRCA1	c.2428A>T	p.N810Y	Missense	10/23	-
3-178922364-G-A	PIK3CA	c.1133G>A	p.C378Y	Missense	6/21	-
3-178922328-C-G	PIK3CA	c.1097C>G	p.P366R	Missense	6/21	-
3-178921549-T-C	PIK3CA	c.1031T>C	p.V344A	Missense	5/21	-
3-178928073-G-A	PIK3CA	c.1351G>A	p.G451R	Missense	8/21	-
3-178928073-G-C	PIK3CA	c.1351G>C	p.G451R	Missense	8/21	-
3-178936083-A-C	PIK3CA	c.1625A>C	p.E542A	Missense	10/21	-
3-178928079-G-C	PIK3CA	c.1357G>C	p.E453Q	Missense	8/21	-
10-89624297-A-G	PTEN	c.71A>G	p.D24G	Missense	1/9	-
3-178937498-C-G	PIK3CA	c.1886C>G	p.S629C	Missense	12/21	-
4-55133559-A-G	PDGFRA	c.863A>G	p.Y288C	Missense	6/23	-
17-37881312-A-T	ERBB2	c.2504A>T	p.Y835F	Missense	21/27	-
17-7577097-C-A	TP53	c.841G>T	p.D281Y	Missense	8/11	-
17-7578455-C-T	TP53	c.475G>A	p.A159T	Missense	5/11	-
3-178952019-C-G	PIK3CA	c.3074C>G	p.T1025S	Missense	21/21	-
17-7577508-T-C	TP53	c.773A>G	p.E258G	Missense	7/11	-
17-7577544-A-G	TP53	c.737T>C	p.M246T	Missense	7/11	-
17-7579394-G-A	TP53	c.293C>T	p.P98L	Missense	4/11	-
17-7579514-G-A	TP53	c.173C>T	p.P58L	Missense	4/11	-
17-7578478-G-A	TP53	c.452C>T	p.P151L	Missense	5/11	-
17-7578404-A-C	TP53	c.526T>G	p.C176G	Missense	5/11	-
17-7577529-A-T	TP53	c.752T>A	p.I251N	Missense	7/11	-
17-7577030-C-T	TP53	c.908G>A	p.S303N	Missense	8/11	-
17-7579407-A-G	TP53	c.280T>C	p.S94P	Missense	4/11	-
17-37879854-G-A	ERBB2	c.2149G>A	p.E717K	Missense	18/27	-
17-41247921-C-A	BRCA1	c.612G>T	p.L204F	Missense	9/23	-
17-41247921-C-G	BRCA1	c.612G>C	p.L204F	Missense	9/23	-
X-47426121-C-T	ARAF	c.641C>T	p.S214F	Missense	7/16	-
14-95557629-T-G	DICER1	c.5438A>C	p.E1813A	Missense	25/27	-
7-140453155-C-G	BRAF	c.1780G>C	p.D594H	Missense	15/18	-
7-140453193-T-G	BRAF	c.1742A>C	p.N581T	Missense	15/18	-
7-140453149-C-T	BRAF	c.1786G>A	p.G596S	Missense	15/18	-
7-140453133-T-G	BRAF	c.1802A>C	p.K601T	Missense	15/18	-
11-69466019-C-T	CCND1	c.857C>T	p.T286I	Missense	5/5	-
12-58145430-C-A	CDK4	c.71G>T	p.R24L	Missense	2/8	-
14-95557630-C-G	DICER1	c.5437G>C	p.E1813Q	Missense	25/27	-
7-55233043-G-C	EGFR	c.1793G>C	p.G598A	Missense	15/28	-
7-55211079-A-G	EGFR	c.322A>G	p.R108G	Missense	3/28	-
17-37880261-G-A	ERBB2	c.2305G>A	p.D769N	Missense	19/27	-
17-37880219-T-A	ERBB2	c.2263T>A	p.L755M	Missense	19/27	-
12-56482341-G-T	ERBB3	c.889G>T	p.D297Y	Missense	8/28	-
17-7577532-G-T	TP53	c.749C>A	p.P250H	Missense	7/11	-
17-7578265-A-C	TP53	c.584T>G	p.I195S	Missense	6/11	-
17-7579367-T-C	TP53	c.320A>G	p.Y107C	Missense	4/11	-
17-7577081-T-G	TP53	c.857A>C	p.E286A	Missense	8/11	-
17-7578467-T-G	TP53	c.463A>C	p.T155P	Missense	5/11	-
17-7579355-A-G	TP53	c.332T>C	p.L111P	Missense	4/11	-
17-7577517-A-C	TP53	c.764T>G	p.I255S	Missense	7/11	-
17-7577130-A-T	TP53	c.808T>A	p.F270I	Missense	8/11	-
17-7577586-A-C	TP53	c.695T>G	p.I232S	Missense	7/11	-
17-7578509-A-G	TP53	c.421T>C	p.C141R	Missense	5/11	-
17-7577112-C-G	TP53	c.826G>C	p.A276P	Missense	8/11	-
17-7577541-T-A	TP53	c.740A>T	p.N247I	Missense	7/11	-
17-7573948-C-A	TP53	c.1079G>T	p.G360V	Missense	10/11	-
17-7579547-G-A	TP53	c.140C>T	p.P47L	Missense	4/11	-
17-7577082-C-G	TP53	c.856G>C	p.E286Q	Missense	8/11	-
17-7578460-A-C	TP53	c.470T>G	p.V157G	Missense	5/11	-
4-55130019-G-T	PDGFRA	c.553G>T	p.G185W	Missense	4/23	-
3-178952072-A-C	PIK3CA	c.3127A>C	p.M1043L	Missense	21/21	-
3-178928226-C-T	PIK3CA	c.1412C>T	p.P471L	Missense	9/21	-
3-178951957-G-C	PIK3CA	c.3012G>C	p.M1004I	Missense	21/21	-
3-178922321-G-A	PIK3CA	c.1090G>A	p.G364R	Missense	6/21	-
3-178922321-G-C	PIK3CA	c.1090G>C	p.G364R	Missense	6/21	-
3-178922325-A-T	PIK3CA	c.1094A>T	p.E365V	Missense	6/21	-
3-178921552-A-C	PIK3CA	c.1034A>C	p.N345T	Missense	5/21	-
3-178948044-A-G	PIK3CA	c.2816A>G	p.D939G	Missense	20/21	-
3-178921567-A-G	PIK3CA	c.1049A>G	p.D350G	Missense	5/21	-
3-178927980-T-G	PIK3CA	c.1258T>G	p.C420G	Missense	8/21	-
3-178951964-G-C	PIK3CA	c.3019G>C	p.G1007R	Missense	21/21	-
3-178916728-G-A	PIK3CA	c.115G>A	p.E39K	Missense	2/21	-
3-138374245-C-A	PIK3CB	c.3199G>T	p.D1067Y	Missense	24/24	-
3-138374244-T-G	PIK3CB	c.3200A>C	p.D1067A	Missense	24/24	-
10-89624305-T-G	PTEN	c.79T>G	p.Y27D	Missense	1/9	-
12-133253185-G-A	POLE	c.856C>T	p.P286S	Missense	9/49	-
12-133253184-G-T	POLE	c.857C>A	p.P286H	Missense	9/49	-
17-7578505-G-T	TP53	c.425C>A	p.P142H	Missense	5/11	-
7-6426893-C-T	RAC1	c.86C>T	p.P29L	Missense	2/6	-
10-89711891-G-A	PTEN	c.509G>A	p.S170N	Missense	6/9	-
10-89692895-G-A	PTEN	c.379G>A	p.G127R	Missense	5/9	-
10-89692895-G-C	PTEN	c.379G>C	p.G127R	Missense	5/9	-
10-89692923-G-T	PTEN	c.407G>T	p.C136F	Missense	5/9	-
17-7577593-T-G	TP53	c.688A>C	p.T230P	Missense	7/11	-
17-7573996-A-C	TP53	c.1031T>G	p.L344R	Missense	10/11	-
17-7579374-C-G	TP53	c.313G>C	p.G105R	Missense	4/11	-
17-7577127-C-G	TP53	c.811G>C	p.E271Q	Missense	8/11	-
17-7578380-C-G	TP53	c.550G>C	p.D184H	Missense	5/11	-
17-7577505-T-A	TP53	c.776A>T	p.D259V	Missense	7/11	-
17-7579361-A-C	TP53	c.326T>G	p.F109C	Missense	4/11	-
17-7578532-A-C	TP53	c.398T>G	p.M133R	Missense	5/11	-
17-7576853-C-A	TP53	c.993G>T	p.Q331H	Missense	9/11	-
17-7576853-C-G	TP53	c.993G>C	p.Q331H	Missense	9/11	-
17-7578440-T-C	TP53	c.490A>G	p.K164E	Missense	5/11	-
17-7578479-G-C	TP53	c.451C>G	p.P151A	Missense	5/11	-
17-7578211-C-G	TP53	c.638G>C	p.R213P	Missense	6/11	-
17-7578509-A-C	TP53	c.421T>G	p.C141G	Missense	5/11	-
17-7578412-A-C	TP53	c.518T>G	p.V173G	Missense	5/11	-
17-7578499-T-G	TP53	c.431A>C	p.Q144P	Missense	5/11	-
17-7579313-G-T	TP53	c.374C>A	p.T125K	Missense	4/11	-
17-7578527-A-C	TP53	c.403T>G	p.C135G	Missense	5/11	-
17-7577096-T-G	TP53	c.842A>C	p.D281A	Missense	8/11	-
17-7577557-A-C	TP53	c.724T>G	p.C242G	Missense	7/11	-
17-7578202-A-C	TP53	c.647T>G	p.V216G	Missense	6/11	-
17-7577575-A-T	TP53	c.706T>A	p.Y236N	Missense	7/11	-
17-7578208-T-A	TP53	c.641A>T	p.H214L	Missense	6/11	-
17-7578203-C-G	TP53	c.646G>C	p.V216L	Missense	6/11	-
17-7578203-C-A	TP53	c.646G>T	p.V216L	Missense	6/11	-
17-7577117-A-G	TP53	c.821T>C	p.V274A	Missense	8/11	-
17-7577123-A-T	TP53	c.815T>A	p.V272E	Missense	8/11	-
17-7578268-A-T	TP53	c.581T>A	p.L194H	Missense	6/11	-
17-7578508-C-A	TP53	c.422G>T	p.C141F	Missense	5/11	-
17-7578394-T-G	TP53	c.536A>C	p.H179P	Missense	5/11	-
17-7577507-T-A	TP53	c.774A>T	p.E258D	Missense	7/11	-
17-7578202-A-T	TP53	c.647T>A	p.V216E	Missense	6/11	-
17-7578412-A-T	TP53	c.518T>A	p.V173E	Missense	5/11	-
17-7578191-A-C	TP53	c.658T>G	p.Y220D	Missense	6/11	-
17-7577095-G-C	TP53	c.843C>G	p.D281E	Missense	8/11	-
17-7577555-G-C	TP53	c.726C>G	p.C242W	Missense	7/11	-
17-7578402-G-C	TP53	c.528C>G	p.C176W	Missense	5/11	-
17-7577130-A-C	TP53	c.808T>G	p.F270V	Missense	8/11	-
17-7578527-A-T	TP53	c.403T>A	p.C135S	Missense	5/11	-
17-7578526-C-G	TP53	c.404G>C	p.C135S	Missense	5/11	-
17-7579355-A-C	TP53	c.332T>G	p.L111R	Missense	4/11	-
17-7577081-T-A	TP53	c.857A>T	p.E286V	Missense	8/11	-
17-7579314-T-G	TP53	c.373A>C	p.T125P	Missense	4/11	-
17-7578235-T-G	TP53	c.614A>C	p.Y205S	Missense	6/11	-
17-7577551-C-G	TP53	c.730G>C	p.G244R	Missense	7/11	-
17-7577581-A-T	TP53	c.700T>A	p.Y234N	Missense	7/11	-
17-7579355-A-T	TP53	c.332T>A	p.L111Q	Missense	4/11	-
17-7577565-T-G	TP53	c.716A>C	p.N239T	Missense	7/11	-
17-7578509-A-T	TP53	c.421T>A	p.C141S	Missense	5/11	-
17-7578508-C-G	TP53	c.422G>C	p.C141S	Missense	5/11	-
17-7577117-A-T	TP53	c.821T>A	p.V274D	Missense	8/11	-
17-7577571-A-T	TP53	c.710T>A	p.M237K	Missense	7/11	-
17-7577081-T-C	TP53	c.857A>G	p.E286G	Missense	8/11	-
17-7578263-G-C	TP53	c.586C>G	p.R196G	Missense	6/11	-
17-7578209-G-C	TP53	c.640C>G	p.H214D	Missense	6/11	-
7-140439727-C-T	BRAF	c.2012G>A	p.R671Q	Missense	17/18	-
7-55221800-G-A	EGFR	c.844G>A	p.E282K	Missense	7/28	-
7-55211097-G-A	EGFR	c.340G>A	p.E114K	Missense	3/28	-
17-37883561-A-C	ERBB2	c.3173A>C	p.D1058A	Missense	26/27	-
3-178937452-T-A	PIK3CA	c.1840T>A	p.F614I	Missense	12/21	-
3-178942489-C-T	PIK3CA	c.2296C>T	p.L766F	Missense	16/21	-
3-178952063-A-G	PIK3CA	c.3118A>G	p.M1040V	Missense	21/21	-
3-178927430-G-A	PIK3CA	c.1193G>A	p.R398H	Missense	7/21	-
3-138474685-C-T	PIK3CB	c.308G>A	p.R103K	Missense	4/24	-
5-67590467-A-T	PIK3R1	c.1529A>T	p.E510V	Missense	12/16	-
3-138374293-C-T	PIK3CB	c.3151G>A	p.E1051K	Missense	24/24	-
5-67589627-G-A	PIK3R1	c.1390G>A	p.D464N	Missense	11/16	-
1-9784395-G-A	PIK3CD	c.2780G>A	p.R927H	Missense	22/24	-
3-138403480-G-A	PIK3CB	c.2302C>T	p.L768F	Missense	17/24	-
19-50909490-C-T	POLD1	c.1294C>T	p.R432W	Missense	11/27	-
3-138384011-G-C	PIK3CB	c.2539C>G	p.R847G	Missense	20/24	-
12-133256597-C-G	POLE	c.366G>C	p.K122N	Missense	5/49	-
12-133256597-C-A	POLE	c.366G>T	p.K122N	Missense	5/49	-
12-133244209-C-G	POLE	c.2199G>C	p.K733N	Missense	20/49	-
12-133244209-C-A	POLE	c.2199G>T	p.K733N	Missense	20/49	-
19-50905959-C-T	POLD1	c.931C>T	p.R311C	Missense	8/27	-
9-21971156-C-T	CDKN2A	c.202G>A	p.A68T	Missense	2/3	-
12-133250202-C-T	POLE	c.1318G>A	p.D440N	Missense	13/49	-
X-47429359-G-A	ARAF	c.1487G>A	p.G496E	Missense	14/16	-
X-47430771-G-A	ARAF	c.1736G>A	p.R579Q	Missense	16/16	-
12-133248835-T-C	POLE	c.1760A>G	p.K587R	Missense	16/49	-
7-140439646-T-C	BRAF	c.2093A>G	p.K698R	Missense	17/18	-
7-140476796-A-G	BRAF	c.1610T>C	p.L537S	Missense	13/18	-
17-7578197-C-T	TP53	c.652G>A	p.V218M	Missense	6/11	-
2-29519891-C-A	ALK	c.1680G>T	p.L560F	Missense	9/29	-
7-55231430-C-T	EGFR	c.1636C>T	p.P546S	Missense	14/28	-
2-29497967-G-A	ALK	c.2039C>T	p.T680I	Missense	11/29	-
2-29519891-C-G	ALK	c.1680G>C	p.L560F	Missense	9/29	-
17-7578202-A-G	TP53	c.647T>C	p.V216A	Missense	6/11	-
2-29543736-A-G	ALK	c.1427T>C	p.V476A	Missense	7/29	-
3-178943785-C-T	PIK3CA	c.2452C>T	p.R818C	Missense	17/21	-
17-7577049-G-C	TP53	c.889C>G	p.H297D	Missense	8/11	-
4-55133806-G-A	PDGFRA	c.1019G>A	p.R340Q	Missense	7/23	-
17-7579403-G-A	TP53	c.284C>T	p.S95F	Missense	4/11	-
12-133241915-G-A	POLE	c.2441C>T	p.S814F	Missense	21/49	-
1-16464489-C-T	EPHA2	c.1171G>A	p.G391R	Missense	5/17	-
7-140453096-C-G	BRAF	c.1839G>C	p.L613F	Missense	15/18	-
12-133249766-G-A	POLE	c.1457C>T	p.P486L	Missense	14/49	-
12-112888162-G-C	PTPN11	c.178G>C	p.G60R	Missense	3/16	-
17-7577115-A-C	TP53	c.823T>G	p.C275G	Missense	8/11	-
17-7577502-G-T	TP53	c.779C>A	p.S260Y	Missense	7/11	-
19-50918799-C-T	POLD1	c.2669C>T	p.A890V	Missense	21/27	-
4-55139771-T-C	PDGFRA	c.1432T>C	p.S478P	Missense	10/23	-
17-7577511-A-C	TP53	c.770T>G	p.L257R	Missense	7/11	-
17-7577520-A-G	TP53	c.761T>C	p.I254T	Missense	7/11	-
19-50905076-G-A	POLD1	c.358G>A	p.G120S	Missense	4/27	-
7-55242433-G-A	EGFR	c.2203G>A	p.G735S	Missense	19/28	-
2-29519818-C-T	ALK	c.1753G>A	p.A585T	Missense	9/29	-
17-7578445-A-T	TP53	c.485T>A	p.I162N	Missense	5/11	-
17-7578448-G-T	TP53	c.482C>A	p.A161D	Missense	5/11	-
17-7577529-A-G	TP53	c.752T>C	p.I251T	Missense	7/11	-
17-7576854-T-C	TP53	c.992A>G	p.Q331R	Missense	9/11	-
17-7578490-A-T	TP53	c.440T>A	p.V147D	Missense	5/11	-
17-7578554-A-C	TP53	c.376T>G	p.Y126D	Missense	5/11	-
17-37881378-A-G	ERBB2	c.2570A>G	p.N857S	Missense	21/27	-
12-133214645-C-T	POLE	c.5633G>A	p.R1878H	Missense	41/49	-
3-178916706-A-G	PIK3CA	c.93A>G	p.I31M	Missense	2/21	-
7-55259446-A-T	EGFR	c.2504A>T	p.H835L	Missense	21/28	-
7-140477854-A-C	BRAF	c.1454T>G	p.L485W	Missense	12/18	-
17-7578214-A-G	TP53	c.635T>C	p.F212S	Missense	6/11	-
17-7577111-G-C	TP53	c.827C>G	p.A276G	Missense	8/11	-
12-133226406-C-A	POLE	c.3652G>T	p.V1218L	Missense	30/49	-
7-55233012-G-A	EGFR	c.1762G>A	p.G588S	Missense	15/28	-
17-7578197-C-A	TP53	c.652G>T	p.V218L	Missense	6/11	-
17-7578196-A-T	TP53	c.653T>A	p.V218E	Missense	6/11	-
12-133263871-C-A	POLE	c.31G>T	p.A11S	Missense	1/49	-
17-7576926-G-A	TP53	c.920C>T	p.A307V	Missense	9/11	-
7-55259454-C-A	EGFR	c.2512C>A	p.L838M	Missense	21/28	-
4-55141026-C-T	PDGFRA	c.1672C>T	p.R558C	Missense	12/23	-
17-41276053-T-C	BRCA1	c.61A>G	p.I21V	Missense	2/23	-
17-41276044-A-G	BRCA1	c.70T>C	p.C24R	Missense	2/23	-
17-41267762-A-C	BRCA1	c.115T>G	p.C39G	Missense	3/23	-
17-41267761-C-A	BRCA1	c.116G>T	p.C39F	Missense	3/23	-
17-41267761-C-T	BRCA1	c.116G>A	p.C39Y	Missense	3/23	-
17-41267753-T-C	BRCA1	c.124A>G	p.I42V	Missense	3/23	-
17-41267746-C-A	BRCA1	c.131G>T	p.C44F	Missense	3/23	-
17-41258531-G-T	BRCA1	c.154C>A	p.L52I	Missense	4/23	-
17-41258531-G-A	BRCA1	c.154C>T	p.L52F	Missense	4/23	-
17-41256919-G-C	BRCA1	c.267C>G	p.I89M	Missense	5/23	-
17-41215927-C-T	BRCA1	c.5116G>A	p.G1706R	Missense	17/23	-
17-41215927-C-G	BRCA1	c.5116G>C	p.G1706R	Missense	17/23	-
17-7578460-A-G	TP53	c.470T>C	p.V157A	Missense	5/11	-
12-133202313-G-A	POLE	c.6575C>T	p.A2192V	Missense	47/49	-
7-55249005-G-C	EGFR	c.2303G>C	p.S768T	Missense	20/28	-
17-7576857-A-G	TP53	c.989T>C	p.L330P	Missense	9/11	-
12-133220557-G-C	POLE	c.4156C>G	p.R1386G	Missense	33/49	-
17-7579509-G-T	TP53	c.178C>A	p.P60T	Missense	4/11	-
12-133256117-G-A	POLE	c.544C>T	p.H182Y	Missense	6/49	-
3-138453578-C-G	PIK3CB	c.870G>C	p.K290N	Missense	7/24	-
3-138453578-C-A	PIK3CB	c.870G>T	p.K290N	Missense	7/24	-
17-37880997-G-A	ERBB2	c.2326G>A	p.G776S	Missense	20/27	-
17-7577028-T-C	TP53	c.910A>G	p.T304A	Missense	8/11	-
5-67589147-A-G	PIK3R1	c.1135A>G	p.K379E	Missense	10/16	-
17-7578530-A-T	TP53	c.400T>A	p.F134I	Missense	5/11	-
7-140453179-C-T	BRAF	c.1756G>A	p.E586K	Missense	15/18	-
4-55152108-C-T	PDGFRA	c.2540C>T	p.S847L	Missense	18/23	-
7-140481408-G-A	BRAF	c.1400C>T	p.S467L	Missense	11/18	-
17-41276065-C-T	BRCA1	c.49G>A	p.A17T	Missense	2/23	-
4-55152032-C-T	PDGFRA	c.2464C>T	p.R822C	Missense	18/23	-
7-55249130-G-A	EGFR	c.2428G>A	p.G810S	Missense	20/28	-
7-55259551-A-G	EGFR	c.2609A>G	p.H870R	Missense	21/28	-
17-7578439-T-G	TP53	c.491A>C	p.K164T	Missense	5/11	-
7-55233036-C-T	EGFR	c.1786C>T	p.P596S	Missense	15/28	-
17-7578410-T-A	TP53	c.520A>T	p.R174W	Missense	5/11	-
17-7577528-G-C	TP53	c.753C>G	p.I251M	Missense	7/11	-
17-7578253-C-T	TP53	c.596G>A	p.G199E	Missense	6/11	-
17-7578239-C-T	TP53	c.610G>A	p.E204K	Missense	6/11	-
17-7578455-C-A	TP53	c.475G>T	p.A159S	Missense	5/11	-
3-138374305-C-T	PIK3CB	c.3139G>A	p.E1047K	Missense	24/24	-
13-32907359-A-C	BRCA2	c.1744A>C	p.T582P	Missense	10/27	-
17-7572934-G-A	TP53	c.1175C>T	p.S392L	Missense	11/11	-
13-32937362-A-G	BRCA2	c.8023A>G	p.I2675V	Missense	18/27	-
17-7573991-C-T	TP53	c.1036G>A	p.E346K	Missense	10/11	-
17-7578283-G-A	TP53	c.566C>T	p.A189V	Missense	6/11	-
17-7579470-C-T	TP53	c.217G>A	p.V73M	Missense	4/11	-
17-7579542-C-G	TP53	c.145G>C	p.D49H	Missense	4/11	-
17-7579885-C-T	TP53	c.28G>A	p.V10I	Missense	2/11	-
17-7577126-T-A	TP53	c.812A>T	p.E271V	Missense	8/11	-
17-41243800-C-T	BRCA1	c.3748G>A	p.E1250K	Missense	10/23	-
17-41244526-T-C	BRCA1	c.3022A>G	p.M1008V	Missense	10/23	-
12-133244190-C-T	POLE	c.2218G>A	p.E740K	Missense	20/49	-
12-133244109-C-T	POLE	c.2299G>A	p.E767K	Missense	20/49	-
17-41256957-T-C	BRCA1	c.229A>G	p.T77A	Missense	5/23	-
10-89690828-G-A	PTEN	c.235G>A	p.A79T	Missense	4/9	-
17-41258510-A-C	BRCA1	c.175T>G	p.S59A	Missense	4/23	-
17-41276079-T-C	BRCA1	c.35A>G	p.Q12R	Missense	2/23	-
7-140439656-C-T	BRAF	c.2083G>A	p.E695K	Missense	17/18	-
17-7579352-C-T	TP53	c.335G>A	p.G112D	Missense	4/11	-
17-7578418-T-C	TP53	c.512A>G	p.E171G	Missense	5/11	-
17-7578251-T-C	TP53	c.598A>G	p.N200D	Missense	6/11	-
17-7579515-G-T	TP53	c.172C>A	p.P58T	Missense	4/11	-
17-7579334-G-A	TP53	c.353C>T	p.T118I	Missense	4/11	-
17-7577109-A-T	TP53	c.829T>A	p.C277S	Missense	8/11	-
17-7577108-C-G	TP53	c.830G>C	p.C277S	Missense	8/11	-
17-7579515-G-A	TP53	c.172C>T	p.P58S	Missense	4/11	-
19-50919770-G-A	POLD1	c.2938G>A	p.E980K	Missense	23/27	-
17-7572973-C-T	TP53	c.1136G>A	p.R379H	Missense	11/11	-
17-7578502-A-C	TP53	c.428T>G	p.V143G	Missense	5/11	-
17-7577597-G-T	TP53	c.684C>A	p.D228E	Missense	7/11	-
17-7578400-G-A	TP53	c.530C>T	p.P177L	Missense	5/11	-
17-7578446-T-C	TP53	c.484A>G	p.I162V	Missense	5/11	-
17-7577552-C-T	TP53	c.729G>A	p.M243I	Missense	7/11	-
7-140434564-C-T	BRAF	c.2134G>A	p.A712T	Missense	18/18	-
17-41244007-C-T	BRCA1	c.3541G>A	p.V1181I	Missense	10/23	-
7-140481393-T-C	BRAF	c.1415A>G	p.Y472C	Missense	11/18	-
7-55241620-G-A	EGFR	c.2068G>A	p.E690K	Missense	18/28	-
17-41223063-G-C	BRCA1	c.4868C>G	p.A1623G	Missense	15/23	-
17-7577520-A-T	TP53	c.761T>A	p.I254N	Missense	7/11	-
17-37868210-T-C	ERBB2	c.931T>C	p.C311R	Missense	8/27	-
17-37868241-A-G	ERBB2	c.962A>G	p.E321G	Missense	8/27	-
17-37868279-T-A	ERBB2	c.1000T>A	p.C334S	Missense	8/27	-
17-37868280-G-C	ERBB2	c.1001G>C	p.C334S	Missense	8/27	-
6-152419917-C-A	ESR1	c.1604C>A	p.P535H	Missense	8/8	-
17-37881616-C-T	ERBB2	c.2686C>T	p.R896C	Missense	22/27	-
17-37868205-G-A	ERBB2	c.926G>A	p.G309E	Missense	8/27	-
4-55594262-T-A	KIT	c.1965T>A	p.N655K	Missense	13/21	-
4-55595599-C-T	KIT	c.2089C>T	p.H697Y	Missense	14/21	-
17-41276070-A-G	BRCA1	c.44T>C	p.I15T	Missense	2/23	-
17-41256900-C-T	BRCA1	c.286G>A	p.D96N	Missense	5/23	-
3-178936097-G-A	PIK3CA	c.1639G>A	p.E547K	Missense	10/21	-
17-7578496-A-T	TP53	c.434T>A	p.L145Q	Missense	5/11	-
7-55249017-C-G	EGFR	c.2315C>G	p.P772R	Missense	20/28	-
7-55233109-G-A	EGFR	c.1859G>A	p.C620Y	Missense	15/28	-
12-133244132-C-T	POLE	c.2276G>A	p.R759H	Missense	20/49	-
19-50905929-G-A	POLD1	c.901G>A	p.E301K	Missense	8/27	-
7-55249028-C-G	EGFR	c.2326C>G	p.R776G	Missense	20/28	-
13-32912060-C-T	BRCA2	c.3568C>T	p.R1190W	Missense	11/27	-
17-7577506-C-G	TP53	c.775G>C	p.D259H	Missense	7/11	-
17-41226387-C-A	BRCA1	c.4636G>T	p.D1546Y	Missense	14/23	-
17-41223091-G-A	BRCA1	c.4840C>T	p.P1614S	Missense	15/23	-
17-41226387-C-T	BRCA1	c.4636G>A	p.D1546N	Missense	14/23	-
17-41243713-C-T	BRCA1	c.3835G>A	p.A1279T	Missense	10/23	-
17-41243725-T-C	BRCA1	c.3823A>G	p.I1275V	Missense	10/23	-
17-41243857-A-G	BRCA1	c.3691T>C	p.F1231L	Missense	10/23	-
17-41243908-C-T	BRCA1	c.3640G>A	p.E1214K	Missense	10/23	-
17-41244252-G-A	BRCA1	c.3296C>T	p.P1099L	Missense	10/23	-
17-41244418-T-C	BRCA1	c.3130A>G	p.I1044V	Missense	10/23	-
17-41244952-G-A	BRCA1	c.2596C>T	p.R866C	Missense	10/23	-
17-41245023-T-C	BRCA1	c.2525A>G	p.E842G	Missense	10/23	-
17-41245136-C-G	BRCA1	c.2412G>C	p.Q804H	Missense	10/23	-
17-41256266-T-C	BRCA1	c.314A>G	p.Y105C	Missense	6/23	-
17-41246547-G-A	BRCA1	c.1001C>T	p.P334L	Missense	10/23	-
17-41258486-C-A	BRCA1	c.199G>T	p.D67Y	Missense	4/23	-
17-41267746-C-T	BRCA1	c.131G>A	p.C44Y	Missense	3/23	-
17-41267747-A-T	BRCA1	c.130T>A	p.C44S	Missense	3/23	-
17-41267746-C-G	BRCA1	c.131G>C	p.C44S	Missense	3/23	-
17-41276037-A-T	BRCA1	c.77T>A	p.I26N	Missense	2/23	-
17-41276049-A-G	BRCA1	c.65T>C	p.L22S	Missense	2/23	-
13-32893313-A-C	BRCA2	c.167A>C	p.N56T	Missense	3/27	-
13-32900750-G-A	BRCA2	c.631G>A	p.V211I	Missense	7/27	-
13-32907129-T-C	BRCA2	c.1514T>C	p.I505T	Missense	10/27	-
13-32912174-A-G	BRCA2	c.3682A>G	p.N1228D	Missense	11/27	-
13-32912582-A-C	BRCA2	c.4090A>C	p.I1364L	Missense	11/27	-
13-32913062-T-G	BRCA2	c.4570T>G	p.F1524V	Missense	11/27	-
13-32913562-A-C	BRCA2	c.5070A>C	p.K1690N	Missense	11/27	-
13-32914196-G-A	BRCA2	c.5704G>A	p.D1902N	Missense	11/27	-
17-7577046-C-T	TP53	c.892G>A	p.E298K	Missense	8/11	-
13-32915240-A-G	BRCA2	c.6748A>G	p.T2250A	Missense	11/27	-
19-50920486-C-T	POLD1	c.3178C>T	p.R1060C	Missense	26/27	-
13-32921033-G-C	BRCA2	c.7007G>C	p.R2336P	Missense	13/27	-
13-32972695-A-G	BRCA2	c.10045A>G	p.T3349A	Missense	27/27	-
12-133225562-C-T	POLE	c.4102G>A	p.V1368M	Missense	32/49	-
17-7573987-G-T	TP53	c.1040C>A	p.A347D	Missense	10/11	-
17-7577586-A-G	TP53	c.695T>C	p.I232T	Missense	7/11	-
17-7578539-T-A	TP53	c.391A>T	p.N131Y	Missense	5/11	-
17-7579431-C-T	TP53	c.256G>A	p.A86T	Missense	4/11	-
17-7579439-G-A	TP53	c.248C>T	p.A83V	Missense	4/11	-
17-7579481-G-C	TP53	c.206C>G	p.A69G	Missense	4/11	-
17-7579542-C-T	TP53	c.145G>A	p.D49N	Missense	4/11	-
17-7577090-C-T	TP53	c.848G>A	p.R283H	Missense	8/11	-
17-7577093-C-A	TP53	c.845G>T	p.R282L	Missense	8/11	-
17-7577111-G-T	TP53	c.827C>A	p.A276D	Missense	8/11	-
17-7577530-T-G	TP53	c.751A>C	p.I251L	Missense	7/11	-
17-7577530-T-A	TP53	c.751A>T	p.I251F	Missense	7/11	-
17-41276074-C-T	BRCA1	c.40G>A	p.V14I	Missense	2/23	-
17-41276086-C-T	BRCA1	c.28G>A	p.E10K	Missense	2/23	-
17-41276086-C-G	BRCA1	c.28G>C	p.E10Q	Missense	2/23	-
17-41276085-T-G	BRCA1	c.29A>C	p.E10A	Missense	2/23	-
17-41276085-T-C	BRCA1	c.29A>G	p.E10G	Missense	2/23	-
17-41276085-T-A	BRCA1	c.29A>T	p.E10V	Missense	2/23	-
17-41276083-C-T	BRCA1	c.31G>A	p.V11I	Missense	2/23	-
17-41276082-A-T	BRCA1	c.32T>A	p.V11E	Missense	2/23	-
17-41276082-A-G	BRCA1	c.32T>C	p.V11A	Missense	2/23	-
17-41276079-T-A	BRCA1	c.35A>T	p.Q12L	Missense	2/23	-
17-41276082-A-C	BRCA1	c.32T>G	p.V11G	Missense	2/23	-
17-41276080-G-T	BRCA1	c.34C>A	p.Q12K	Missense	2/23	-
17-41276079-T-G	BRCA1	c.35A>C	p.Q12P	Missense	2/23	-
17-41276076-T-G	BRCA1	c.38A>C	p.N13T	Missense	2/23	-
17-41276076-T-C	BRCA1	c.38A>G	p.N13S	Missense	2/23	-
17-41276073-A-G	BRCA1	c.41T>C	p.V14A	Missense	2/23	-
17-41276071-T-C	BRCA1	c.43A>G	p.I15V	Missense	2/23	-
17-41276071-T-A	BRCA1	c.43A>T	p.I15F	Missense	2/23	-
17-41276070-A-T	BRCA1	c.44T>A	p.I15N	Missense	2/23	-
17-41276070-A-C	BRCA1	c.44T>G	p.I15S	Missense	2/23	-
17-41276068-T-G	BRCA1	c.46A>C	p.N16H	Missense	2/23	-
17-41276069-A-C	BRCA1	c.45T>G	p.I15M	Missense	2/23	-
17-41276068-T-C	BRCA1	c.46A>G	p.N16D	Missense	2/23	-
17-41276065-C-G	BRCA1	c.49G>C	p.A17P	Missense	2/23	-
17-41276065-C-A	BRCA1	c.49G>T	p.A17S	Missense	2/23	-
17-41276064-G-T	BRCA1	c.50C>A	p.A17D	Missense	2/23	-
17-41276064-G-C	BRCA1	c.50C>G	p.A17G	Missense	2/23	-
17-41276064-G-A	BRCA1	c.50C>T	p.A17V	Missense	2/23	-
17-41276061-A-T	BRCA1	c.53T>A	p.M18K	Missense	2/23	-
17-41276061-A-C	BRCA1	c.53T>G	p.M18R	Missense	2/23	-
17-41276059-G-C	BRCA1	c.55C>G	p.Q19E	Missense	2/23	-
17-41276058-T-G	BRCA1	c.56A>C	p.Q19P	Missense	2/23	-
17-41276058-T-C	BRCA1	c.56A>G	p.Q19R	Missense	2/23	-
17-41276058-T-A	BRCA1	c.56A>T	p.Q19L	Missense	2/23	-
17-41276052-A-G	BRCA1	c.62T>C	p.I21T	Missense	2/23	-
17-41276055-T-G	BRCA1	c.59A>C	p.K20T	Missense	2/23	-
17-41276055-T-A	BRCA1	c.59A>T	p.K20I	Missense	2/23	-
17-41276053-T-G	BRCA1	c.61A>C	p.I21L	Missense	2/23	-
17-41276053-T-A	BRCA1	c.61A>T	p.I21F	Missense	2/23	-
17-41276052-A-T	BRCA1	c.62T>A	p.I21N	Missense	2/23	-
17-41276052-A-C	BRCA1	c.62T>G	p.I21S	Missense	2/23	-
17-41276050-A-T	BRCA1	c.64T>A	p.L22I	Missense	2/23	-
17-41276050-A-C	BRCA1	c.64T>G	p.L22V	Missense	2/23	-
17-41276047-C-G	BRCA1	c.67G>C	p.E23Q	Missense	2/23	-
17-41276046-T-G	BRCA1	c.68A>C	p.E23A	Missense	2/23	-
17-41276044-A-C	BRCA1	c.70T>G	p.C24G	Missense	2/23	-
17-41276043-C-A	BRCA1	c.71G>T	p.C24F	Missense	2/23	-
17-41276042-A-C	BRCA1	c.72T>G	p.C24W	Missense	2/23	-
17-41276068-T-A	BRCA1	c.46A>T	p.N16Y	Missense	2/23	-
17-41276067-T-G	BRCA1	c.47A>C	p.N16T	Missense	2/23	-
17-41276067-T-C	BRCA1	c.47A>G	p.N16S	Missense	2/23	-
17-41276067-T-A	BRCA1	c.47A>T	p.N16I	Missense	2/23	-
17-41276038-T-C	BRCA1	c.76A>G	p.I26V	Missense	2/23	-
17-41276036-G-C	BRCA1	c.78C>G	p.I26M	Missense	2/23	-
17-41267794-A-T	BRCA1	c.83T>A	p.L28Q	Missense	3/23	-
17-41267794-A-C	BRCA1	c.83T>G	p.L28R	Missense	3/23	-
17-41267792-C-T	BRCA1	c.85G>A	p.E29K	Missense	3/23	-
17-41267774-C-T	BRCA1	c.103G>A	p.V35I	Missense	3/23	-
17-41276040-G-C	BRCA1	c.74C>G	p.P25R	Missense	2/23	-
17-41276040-G-A	BRCA1	c.74C>T	p.P25L	Missense	2/23	-
17-41276038-T-G	BRCA1	c.76A>C	p.I26L	Missense	2/23	-
17-41267789-A-T	BRCA1	c.88T>A	p.L30M	Missense	3/23	-
17-41267789-A-C	BRCA1	c.88T>G	p.L30V	Missense	3/23	-
17-41267788-A-G	BRCA1	c.89T>C	p.L30S	Missense	3/23	-
17-41267788-A-C	BRCA1	c.89T>G	p.L30W	Missense	3/23	-
17-41267779-T-A	BRCA1	c.98A>T	p.E33V	Missense	3/23	-
17-41267786-T-G	BRCA1	c.91A>C	p.I31L	Missense	3/23	-
17-41267786-T-C	BRCA1	c.91A>G	p.I31V	Missense	3/23	-
17-41267786-T-A	BRCA1	c.91A>T	p.I31F	Missense	3/23	-
17-41267785-A-T	BRCA1	c.92T>A	p.I31N	Missense	3/23	-
17-41267785-A-G	BRCA1	c.92T>C	p.I31T	Missense	3/23	-
17-41267785-A-C	BRCA1	c.92T>G	p.I31S	Missense	3/23	-
17-41267783-T-G	BRCA1	c.94A>C	p.K32Q	Missense	3/23	-
17-41267783-T-C	BRCA1	c.94A>G	p.K32E	Missense	3/23	-
17-41267782-T-G	BRCA1	c.95A>C	p.K32T	Missense	3/23	-
17-41267782-T-C	BRCA1	c.95A>G	p.K32R	Missense	3/23	-
17-41267782-T-A	BRCA1	c.95A>T	p.K32M	Missense	3/23	-
17-41267777-G-T	BRCA1	c.100C>A	p.P34T	Missense	3/23	-
17-41267777-G-C	BRCA1	c.100C>G	p.P34A	Missense	3/23	-
17-41267777-G-A	BRCA1	c.100C>T	p.P34S	Missense	3/23	-
17-41267765-T-C	BRCA1	c.112A>G	p.K38E	Missense	3/23	-
17-41267776-G-T	BRCA1	c.101C>A	p.P34H	Missense	3/23	-
17-41267773-A-C	BRCA1	c.104T>G	p.V35G	Missense	3/23	-
17-41267771-A-T	BRCA1	c.106T>A	p.S36T	Missense	3/23	-
17-41267771-A-C	BRCA1	c.106T>G	p.S36A	Missense	3/23	-
17-41267768-T-G	BRCA1	c.109A>C	p.T37P	Missense	3/23	-
17-41267768-T-C	BRCA1	c.109A>G	p.T37A	Missense	3/23	-
17-41267768-T-A	BRCA1	c.109A>T	p.T37S	Missense	3/23	-
17-41267765-T-G	BRCA1	c.112A>C	p.K38Q	Missense	3/23	-
17-41267764-T-G	BRCA1	c.113A>C	p.K38T	Missense	3/23	-
17-41267764-T-C	BRCA1	c.113A>G	p.K38R	Missense	3/23	-
17-41267764-T-A	BRCA1	c.113A>T	p.K38M	Missense	3/23	-
17-41267758-T-C	BRCA1	c.119A>G	p.D40G	Missense	3/23	-
17-41267759-C-T	BRCA1	c.118G>A	p.D40N	Missense	3/23	-
17-41267759-C-G	BRCA1	c.118G>C	p.D40H	Missense	3/23	-
17-41267759-C-A	BRCA1	c.118G>T	p.D40Y	Missense	3/23	-
17-41267758-T-G	BRCA1	c.119A>C	p.D40A	Missense	3/23	-
17-41267758-T-A	BRCA1	c.119A>T	p.D40V	Missense	3/23	-
17-41267774-C-G	BRCA1	c.103G>C	p.V35L	Missense	3/23	-
17-41267773-A-T	BRCA1	c.104T>A	p.V35D	Missense	3/23	-
17-41267755-T-G	BRCA1	c.122A>C	p.H41P	Missense	3/23	-
17-41267752-A-G	BRCA1	c.125T>C	p.I42T	Missense	3/23	-
17-41267750-A-C	BRCA1	c.127T>G	p.F43V	Missense	3/23	-
17-41267749-A-T	BRCA1	c.128T>A	p.F43Y	Missense	3/23	-
17-41267749-A-C	BRCA1	c.128T>G	p.F43C	Missense	3/23	-
17-41267747-A-G	BRCA1	c.130T>C	p.C44R	Missense	3/23	-
17-41267745-G-C	BRCA1	c.132C>G	p.C44W	Missense	3/23	-
17-41258549-A-T	BRCA1	c.136T>A	p.F46I	Missense	4/23	-
17-41258549-A-C	BRCA1	c.136T>G	p.F46V	Missense	4/23	-
17-41258548-A-T	BRCA1	c.137T>A	p.F46Y	Missense	4/23	-
17-41258548-A-G	BRCA1	c.137T>C	p.F46S	Missense	4/23	-
17-41258548-A-C	BRCA1	c.137T>G	p.F46C	Missense	4/23	-
17-41258545-C-T	BRCA1	c.140G>A	p.C47Y	Missense	4/23	-
17-41258546-A-T	BRCA1	c.139T>A	p.C47S	Missense	4/23	-
17-41258545-C-G	BRCA1	c.140G>C	p.C47S	Missense	4/23	-
17-41258546-A-G	BRCA1	c.139T>C	p.C47R	Missense	4/23	-
17-41258546-A-C	BRCA1	c.139T>G	p.C47G	Missense	4/23	-
17-41258544-G-C	BRCA1	c.141C>G	p.C47W	Missense	4/23	-
17-41258543-T-C	BRCA1	c.142A>G	p.M48V	Missense	4/23	-
17-41258542-A-T	BRCA1	c.143T>A	p.M48K	Missense	4/23	-
17-41258542-A-C	BRCA1	c.143T>G	p.M48R	Missense	4/23	-
17-41258539-A-T	BRCA1	c.146T>A	p.L49Q	Missense	4/23	-
17-41258540-G-T	BRCA1	c.145C>A	p.L49M	Missense	4/23	-
17-41258540-G-C	BRCA1	c.145C>G	p.L49V	Missense	4/23	-
17-41258539-A-G	BRCA1	c.146T>C	p.L49P	Missense	4/23	-
17-41258539-A-C	BRCA1	c.146T>G	p.L49R	Missense	4/23	-
17-41258537-T-G	BRCA1	c.148A>C	p.K50Q	Missense	4/23	-
17-41258537-T-C	BRCA1	c.148A>G	p.K50E	Missense	4/23	-
17-41258536-T-G	BRCA1	c.149A>C	p.K50T	Missense	4/23	-
17-41258536-T-C	BRCA1	c.149A>G	p.K50R	Missense	4/23	-
17-41258536-T-A	BRCA1	c.149A>T	p.K50I	Missense	4/23	-
17-41258534-G-T	BRCA1	c.151C>A	p.L51I	Missense	4/23	-
17-41258534-G-C	BRCA1	c.151C>G	p.L51V	Missense	4/23	-
17-41258534-G-A	BRCA1	c.151C>T	p.L51F	Missense	4/23	-
17-41258533-A-T	BRCA1	c.152T>A	p.L51H	Missense	4/23	-
17-41258533-A-C	BRCA1	c.152T>G	p.L51R	Missense	4/23	-
17-41258528-T-A	BRCA1	c.157A>T	p.N53Y	Missense	4/23	-
17-41258531-G-C	BRCA1	c.154C>G	p.L52V	Missense	4/23	-
17-41258530-A-G	BRCA1	c.155T>C	p.L52P	Missense	4/23	-
17-41258528-T-G	BRCA1	c.157A>C	p.N53H	Missense	4/23	-
17-41258528-T-C	BRCA1	c.157A>G	p.N53D	Missense	4/23	-
17-41258527-T-C	BRCA1	c.158A>G	p.N53S	Missense	4/23	-
17-41258525-G-T	BRCA1	c.160C>A	p.Q54K	Missense	4/23	-
17-41258525-G-C	BRCA1	c.160C>G	p.Q54E	Missense	4/23	-
17-41258524-T-C	BRCA1	c.161A>G	p.Q54R	Missense	4/23	-
17-41258524-T-A	BRCA1	c.161A>T	p.Q54L	Missense	4/23	-
17-41258522-T-G	BRCA1	c.163A>C	p.K55Q	Missense	4/23	-
17-41258522-T-C	BRCA1	c.163A>G	p.K55E	Missense	4/23	-
17-41258521-T-G	BRCA1	c.164A>C	p.K55T	Missense	4/23	-
17-41258501-G-T	BRCA1	c.184C>A	p.P62T	Missense	4/23	-
17-41258521-T-C	BRCA1	c.164A>G	p.K55R	Missense	4/23	-
17-41258521-T-A	BRCA1	c.164A>T	p.K55M	Missense	4/23	-
17-41258519-T-C	BRCA1	c.166A>G	p.K56E	Missense	4/23	-
17-41258518-T-G	BRCA1	c.167A>C	p.K56T	Missense	4/23	-
17-41258518-T-C	BRCA1	c.167A>G	p.K56R	Missense	4/23	-
17-41258518-T-A	BRCA1	c.167A>T	p.K56I	Missense	4/23	-
17-41258512-G-T	BRCA1	c.173C>A	p.P58H	Missense	4/23	-
17-41258515-C-A	BRCA1	c.170G>T	p.G57V	Missense	4/23	-
17-41258513-G-C	BRCA1	c.172C>G	p.P58A	Missense	4/23	-
17-41258512-G-C	BRCA1	c.173C>G	p.P58R	Missense	4/23	-
17-41258512-G-A	BRCA1	c.173C>T	p.P58L	Missense	4/23	-
17-41258510-A-T	BRCA1	c.175T>A	p.S59T	Missense	4/23	-
17-41258510-A-G	BRCA1	c.175T>C	p.S59P	Missense	4/23	-
17-41258507-G-T	BRCA1	c.178C>A	p.Q60K	Missense	4/23	-
17-41258507-G-C	BRCA1	c.178C>G	p.Q60E	Missense	4/23	-
17-41258503-C-A	BRCA1	c.182G>T	p.C61F	Missense	4/23	-
17-41258506-T-G	BRCA1	c.179A>C	p.Q60P	Missense	4/23	-
17-41258506-T-A	BRCA1	c.179A>T	p.Q60L	Missense	4/23	-
17-41258502-A-C	BRCA1	c.183T>G	p.C61W	Missense	4/23	-
17-41258494-C-A	BRCA1	c.191G>T	p.C64F	Missense	4/23	-
17-41258501-G-C	BRCA1	c.184C>G	p.P62A	Missense	4/23	-
17-41258500-G-T	BRCA1	c.185C>A	p.P62H	Missense	4/23	-
17-41258491-T-G	BRCA1	c.194A>C	p.K65T	Missense	4/23	-
17-41258491-T-C	BRCA1	c.194A>G	p.K65R	Missense	4/23	-
17-41258491-T-A	BRCA1	c.194A>T	p.K65M	Missense	4/23	-
17-41258489-T-A	BRCA1	c.196A>T	p.N66Y	Missense	4/23	-
17-41258488-T-G	BRCA1	c.197A>C	p.N66T	Missense	4/23	-
17-41258488-T-C	BRCA1	c.197A>G	p.N66S	Missense	4/23	-
17-41258488-T-A	BRCA1	c.197A>T	p.N66I	Missense	4/23	-
17-41258486-C-T	BRCA1	c.199G>A	p.D67N	Missense	4/23	-
17-41258486-C-G	BRCA1	c.199G>C	p.D67H	Missense	4/23	-
17-41258485-T-G	BRCA1	c.200A>C	p.D67A	Missense	4/23	-
17-41258493-A-C	BRCA1	c.192T>G	p.C64W	Missense	4/23	-
17-41258492-T-G	BRCA1	c.193A>C	p.K65Q	Missense	4/23	-
17-41258492-T-C	BRCA1	c.193A>G	p.K65E	Missense	4/23	-
17-41258485-T-A	BRCA1	c.200A>T	p.D67V	Missense	4/23	-
17-41258483-T-C	BRCA1	c.202A>G	p.I68V	Missense	4/23	-
17-41258476-T-G	BRCA1	c.209A>C	p.K70T	Missense	4/23	-
17-41258481-T-C	BRCA1	c.204A>G	p.I68M	Missense	4/23	-
17-41258480-T-G	BRCA1	c.205A>C	p.T69P	Missense	4/23	-
17-41258479-G-T	BRCA1	c.206C>A	p.T69N	Missense	4/23	-
17-41258479-G-A	BRCA1	c.206C>T	p.T69I	Missense	4/23	-
17-41258476-T-C	BRCA1	c.209A>G	p.K70R	Missense	4/23	-
17-41258476-T-A	BRCA1	c.209A>T	p.K70I	Missense	4/23	-
17-41258473-C-T	BRCA1	c.212G>A	p.R71K	Missense	4/23	-
17-41256971-C-A	BRCA1	c.215G>T	p.S72I	Missense	5/23	-
17-41258485-T-C	BRCA1	c.200A>G	p.D67G	Missense	4/23	-
17-41256972-T-C	BRCA1	c.214A>G	p.S72G	Missense	5/23	-
17-41256971-C-T	BRCA1	c.215G>A	p.S72N	Missense	5/23	-
17-41256971-C-G	BRCA1	c.215G>C	p.S72T	Missense	5/23	-
17-41256968-A-C	BRCA1	c.218T>G	p.L73R	Missense	5/23	-
17-41256969-G-C	BRCA1	c.217C>G	p.L73V	Missense	5/23	-
17-41256968-A-T	BRCA1	c.218T>A	p.L73Q	Missense	5/23	-
17-41256968-A-G	BRCA1	c.218T>C	p.L73P	Missense	5/23	-
17-41256965-T-A	BRCA1	c.221A>T	p.Q74L	Missense	5/23	-
17-41256966-G-T	BRCA1	c.220C>A	p.Q74K	Missense	5/23	-
17-41256965-T-C	BRCA1	c.221A>G	p.Q74R	Missense	5/23	-
17-41256960-T-C	BRCA1	c.226A>G	p.S76G	Missense	5/23	-
17-41256960-T-A	BRCA1	c.226A>T	p.S76C	Missense	5/23	-
17-41256959-C-T	BRCA1	c.227G>A	p.S76N	Missense	5/23	-
17-41256959-C-A	BRCA1	c.227G>T	p.S76I	Missense	5/23	-
17-41256957-T-G	BRCA1	c.229A>C	p.T77P	Missense	5/23	-
17-41256957-T-A	BRCA1	c.229A>T	p.T77S	Missense	5/23	-
17-41256956-G-T	BRCA1	c.230C>A	p.T77K	Missense	5/23	-
17-41256956-G-A	BRCA1	c.230C>T	p.T77M	Missense	5/23	-
17-41256954-T-C	BRCA1	c.232A>G	p.R78G	Missense	5/23	-
17-41256953-C-T	BRCA1	c.233G>A	p.R78K	Missense	5/23	-
17-41256953-C-G	BRCA1	c.233G>C	p.R78T	Missense	5/23	-
17-41256953-C-A	BRCA1	c.233G>T	p.R78I	Missense	5/23	-
17-41256951-A-C	BRCA1	c.235T>G	p.F79V	Missense	5/23	-
17-41256950-A-T	BRCA1	c.236T>A	p.F79Y	Missense	5/23	-
17-41256950-A-G	BRCA1	c.236T>C	p.F79S	Missense	5/23	-
17-41256950-A-C	BRCA1	c.236T>G	p.F79C	Missense	5/23	-
17-41256948-T-C	BRCA1	c.238A>G	p.S80G	Missense	5/23	-
17-41256962-T-G	BRCA1	c.224A>C	p.E75A	Missense	5/23	-
17-41256947-C-T	BRCA1	c.239G>A	p.S80N	Missense	5/23	-
17-41256947-C-G	BRCA1	c.239G>C	p.S80T	Missense	5/23	-
17-41256947-C-A	BRCA1	c.239G>T	p.S80I	Missense	5/23	-
17-41256945-G-T	BRCA1	c.241C>A	p.Q81K	Missense	5/23	-
17-41256942-G-T	BRCA1	c.244C>A	p.L82I	Missense	5/23	-
17-41256942-G-C	BRCA1	c.244C>G	p.L82V	Missense	5/23	-
17-41256942-G-A	BRCA1	c.244C>T	p.L82F	Missense	5/23	-
17-41256941-A-G	BRCA1	c.245T>C	p.L82P	Missense	5/23	-
17-41256941-A-C	BRCA1	c.245T>G	p.L82R	Missense	5/23	-
17-41256939-C-T	BRCA1	c.247G>A	p.V83I	Missense	5/23	-
17-41256938-A-T	BRCA1	c.248T>A	p.V83D	Missense	5/23	-
17-41256938-A-C	BRCA1	c.248T>G	p.V83G	Missense	5/23	-
17-41256935-T-G	BRCA1	c.251A>C	p.E84A	Missense	5/23	-
17-41256935-T-A	BRCA1	c.251A>T	p.E84V	Missense	5/23	-
17-41256933-C-T	BRCA1	c.253G>A	p.E85K	Missense	5/23	-
17-41256933-C-G	BRCA1	c.253G>C	p.E85Q	Missense	5/23	-
17-41256932-T-G	BRCA1	c.254A>C	p.E85A	Missense	5/23	-
17-41256932-T-C	BRCA1	c.254A>G	p.E85G	Missense	5/23	-
17-41256932-T-A	BRCA1	c.254A>T	p.E85V	Missense	5/23	-
17-41256930-G-T	BRCA1	c.256C>A	p.L86I	Missense	5/23	-
17-41256930-G-C	BRCA1	c.256C>G	p.L86V	Missense	5/23	-
17-41256929-A-T	BRCA1	c.257T>A	p.L86Q	Missense	5/23	-
17-41256929-A-G	BRCA1	c.257T>C	p.L86P	Missense	5/23	-
17-41256929-A-C	BRCA1	c.257T>G	p.L86R	Missense	5/23	-
17-41256927-A-T	BRCA1	c.259T>A	p.L87M	Missense	5/23	-
17-41256926-A-G	BRCA1	c.260T>C	p.L87S	Missense	5/23	-
17-41256926-A-C	BRCA1	c.260T>G	p.L87W	Missense	5/23	-
17-41256924-T-G	BRCA1	c.262A>C	p.K88Q	Missense	5/23	-
17-41256924-T-C	BRCA1	c.262A>G	p.K88E	Missense	5/23	-
17-41256923-T-G	BRCA1	c.263A>C	p.K88T	Missense	5/23	-
17-41256923-T-C	BRCA1	c.263A>G	p.K88R	Missense	5/23	-
17-41256921-T-G	BRCA1	c.265A>C	p.I89L	Missense	5/23	-
17-41256921-T-C	BRCA1	c.265A>G	p.I89V	Missense	5/23	-
17-41256921-T-A	BRCA1	c.265A>T	p.I89F	Missense	5/23	-
17-41256918-T-C	BRCA1	c.268A>G	p.I90V	Missense	5/23	-
17-41256918-T-A	BRCA1	c.268A>T	p.I90F	Missense	5/23	-
17-41256917-A-T	BRCA1	c.269T>A	p.I90N	Missense	5/23	-
17-41256917-A-G	BRCA1	c.269T>C	p.I90T	Missense	5/23	-
17-41256917-A-C	BRCA1	c.269T>G	p.I90S	Missense	5/23	-
17-41256916-A-C	BRCA1	c.270T>G	p.I90M	Missense	5/23	-
17-41256915-A-G	BRCA1	c.271T>C	p.C91R	Missense	5/23	-
17-41256915-A-C	BRCA1	c.271T>G	p.C91G	Missense	5/23	-
17-41256914-C-T	BRCA1	c.272G>A	p.C91Y	Missense	5/23	-
17-41256908-A-T	BRCA1	c.278T>A	p.F93Y	Missense	5/23	-
17-41256945-G-C	BRCA1	c.241C>G	p.Q81E	Missense	5/23	-
17-41256944-T-G	BRCA1	c.242A>C	p.Q81P	Missense	5/23	-
17-41256944-T-C	BRCA1	c.242A>G	p.Q81R	Missense	5/23	-
17-41256944-T-A	BRCA1	c.242A>T	p.Q81L	Missense	5/23	-
17-41256913-A-C	BRCA1	c.273T>G	p.C91W	Missense	5/23	-
17-41256914-C-A	BRCA1	c.272G>T	p.C91F	Missense	5/23	-
17-41256912-C-G	BRCA1	c.274G>C	p.A92P	Missense	5/23	-
17-41256912-C-A	BRCA1	c.274G>T	p.A92S	Missense	5/23	-
17-41256911-G-C	BRCA1	c.275C>G	p.A92G	Missense	5/23	-
17-41256911-G-A	BRCA1	c.275C>T	p.A92V	Missense	5/23	-
17-41256906-G-C	BRCA1	c.280C>G	p.Q94E	Missense	5/23	-
17-41256905-T-C	BRCA1	c.281A>G	p.Q94R	Missense	5/23	-
17-41256905-T-A	BRCA1	c.281A>T	p.Q94L	Missense	5/23	-
17-41256903-G-C	BRCA1	c.283C>G	p.L95V	Missense	5/23	-
17-41256903-G-A	BRCA1	c.283C>T	p.L95F	Missense	5/23	-
17-41256902-A-T	BRCA1	c.284T>A	p.L95H	Missense	5/23	-
17-41256902-A-G	BRCA1	c.284T>C	p.L95P	Missense	5/23	-
17-41256902-A-C	BRCA1	c.284T>G	p.L95R	Missense	5/23	-
17-41256900-C-G	BRCA1	c.286G>C	p.D96H	Missense	5/23	-
17-41256900-C-A	BRCA1	c.286G>T	p.D96Y	Missense	5/23	-
17-41256899-T-G	BRCA1	c.287A>C	p.D96A	Missense	5/23	-
17-41256899-T-C	BRCA1	c.287A>G	p.D96G	Missense	5/23	-
17-41256899-T-A	BRCA1	c.287A>T	p.D96V	Missense	5/23	-
17-41256896-G-A	BRCA1	c.290C>T	p.T97I	Missense	5/23	-
17-41256894-C-G	BRCA1	c.292G>C	p.G98R	Missense	5/23	-
17-41256908-A-G	BRCA1	c.278T>C	p.F93S	Missense	5/23	-
17-41256893-C-A	BRCA1	c.293G>T	p.G98V	Missense	5/23	-
17-41256908-A-C	BRCA1	c.278T>G	p.F93C	Missense	5/23	-
17-41256891-A-C	BRCA1	c.295T>G	p.L99V	Missense	5/23	-
17-41256906-G-T	BRCA1	c.280C>A	p.Q94K	Missense	5/23	-
17-41256903-G-T	BRCA1	c.283C>A	p.L95I	Missense	5/23	-
X-47426043-G-A	ARAF	c.563G>A	p.R188H	Missense	7/16	-
17-7578550-G-C	TP53	c.380C>G	p.S127C	Missense	5/11	-
17-41219705-A-T	BRCA1	c.4994T>A	p.V1665E	Missense	16/23	-
12-133219414-C-T	POLE	c.4720G>A	p.A1574T	Missense	36/49	-
19-50918138-G-A	POLD1	c.2455G>A	p.D819N	Missense	20/27	-
7-55249005-G-A	EGFR	c.2303G>A	p.S768N	Missense	20/28	-
19-50906786-G-T	POLD1	c.1174G>T	p.V392L	Missense	10/27	-
7-55259454-C-G	EGFR	c.2512C>G	p.L838V	Missense	21/28	-
12-133237666-C-A	POLE	c.2949G>T	p.K983N	Missense	25/49	-
12-133237666-C-G	POLE	c.2949G>C	p.K983N	Missense	25/49	-
4-55130043-G-A	PDGFRA	c.577G>A	p.V193I	Missense	4/23	-
2-29416320-C-T	ALK	c.4633G>A	p.V1545I	Missense	29/29	-
17-7577521-T-A	TP53	c.760A>T	p.I254F	Missense	7/11	-
7-55238870-G-A	EGFR	c.1883G>A	p.C628Y	Missense	16/28	-
12-133226441-C-A	POLE	c.3617G>T	p.R1206M	Missense	30/49	-
19-50919687-T-C	POLD1	c.2855T>C	p.I952T	Missense	23/27	-
19-50918160-G-A	POLD1	c.2477G>A	p.C826Y	Missense	20/27	-
17-7576857-A-C	TP53	c.989T>G	p.L330R	Missense	9/11	-
12-133254279-G-A	POLE	c.605C>T	p.T202I	Missense	7/49	-
17-7578415-A-C	TP53	c.515T>G	p.V172G	Missense	5/11	-
19-50910339-G-A	POLD1	c.1594G>A	p.A532T	Missense	13/27	-
6-152415537-T-C	ESR1	c.1387T>C	p.S463P	Missense	7/8	-
19-50921124-C-T	POLD1	c.3244C>T	p.R1082C	Missense	27/27	-
17-7578547-G-A	TP53	c.383C>T	p.P128L	Missense	5/11	-
17-7579433-G-A	TP53	c.254C>T	p.P85L	Missense	4/11	-
17-7577564-G-C	TP53	c.717C>G	p.N239K	Missense	7/11	-
19-50905597-C-T	POLD1	c.725C>T	p.A242V	Missense	6/27	-
17-7573970-C-T	TP53	c.1057G>A	p.A353T	Missense	10/11	-
12-133253159-C-A	POLE	c.882G>T	p.M294I	Missense	9/49	-
19-50906838-G-T	POLD1	c.1226G>T	p.R409L	Missense	10/27	-
17-7577050-G-T	TP53	c.888C>A	p.H296Q	Missense	8/11	-
17-7577050-G-C	TP53	c.888C>G	p.H296Q	Missense	8/11	-
2-29519915-C-T	ALK	c.1656G>A	p.M552I	Missense	9/29	-
12-133215795-C-T	POLE	c.5468G>A	p.R1823H	Missense	40/49	-
12-133214646-G-A	POLE	c.5632C>T	p.R1878C	Missense	41/49	-
12-133236080-C-T	POLE	c.3076G>A	p.D1026N	Missense	26/49	-
17-7579460-G-A	TP53	c.227C>T	p.A76V	Missense	4/11	-
12-133257855-C-T	POLE	c.73G>A	p.A25T	Missense	2/49	-
17-7578419-C-G	TP53	c.511G>C	p.E171Q	Missense	5/11	-
17-7576912-T-C	TP53	c.934A>G	p.T312A	Missense	9/11	-
17-7578530-A-C	TP53	c.400T>G	p.F134V	Missense	5/11	-
17-37665993-G-T	CDK12	c.2645G>T	p.R882L	Missense	7/14	-
17-7578398-G-T	TP53	c.532C>A	p.H178N	Missense	5/11	-
3-138383926-G-T	PIK3CB	c.2624C>A	p.A875D	Missense	20/24	-
3-138383924-A-G	PIK3CB	c.2626T>C	p.F876L	Missense	20/24	-
17-37667817-A-G	CDK12	c.2702A>G	p.Y901C	Missense	8/14	-
17-7578241-A-G	TP53	c.608T>C	p.V203A	Missense	6/11	-
17-7579374-C-T	TP53	c.313G>A	p.G105S	Missense	4/11	-
19-50905542-C-T	POLD1	c.670C>T	p.R224C	Missense	6/27	-
17-7578484-G-A	TP53	c.446C>T	p.S149F	Missense	5/11	-
3-178952018-A-T	PIK3CA	c.3073A>T	p.T1025S	Missense	21/21	-
17-7579384-T-G	TP53	c.303A>C	p.K101N	Missense	4/11	-
17-7579384-T-A	TP53	c.303A>T	p.K101N	Missense	4/11	-
17-7579388-T-C	TP53	c.299A>G	p.Q100R	Missense	4/11	-
7-55241675-A-T	EGFR	c.2123A>T	p.K708M	Missense	18/28	-
17-7579487-G-C	TP53	c.200C>G	p.P67R	Missense	4/11	-
17-7577514-G-T	TP53	c.767C>A	p.T256K	Missense	7/11	-
7-55249053-C-T	EGFR	c.2351C>T	p.S784F	Missense	20/28	-
17-7578467-T-A	TP53	c.463A>T	p.T155S	Missense	5/11	-
17-7578466-G-A	TP53	c.464C>T	p.T155I	Missense	5/11	-
17-7578452-T-A	TP53	c.478A>T	p.M160L	Missense	5/11	-
12-25362830-A-G	KRAS	c.466T>C	p.F156L	Missense	5/5	-
12-25362828-G-C	KRAS	c.468C>G	p.F156L	Missense	5/5	-
12-112888220-A-G	PTPN11	c.236A>G	p.Q79R	Missense	3/16	-
7-140453192-A-C	BRAF	c.1743T>G	p.N581K	Missense	15/18	-
7-140453192-A-T	BRAF	c.1743T>A	p.N581K	Missense	15/18	-
7-140501351-T-G	BRAF	c.721A>C	p.T241P	Missense	6/18	-
17-7578221-T-A	TP53	c.628A>T	p.N210Y	Missense	6/11	-
17-7577584-G-C	TP53	c.697C>G	p.H233D	Missense	7/11	-
17-7578434-A-C	TP53	c.496T>G	p.S166A	Missense	5/11	-
17-7577103-C-T	TP53	c.835G>A	p.G279R	Missense	8/11	-
4-55594197-C-T	KIT	c.1900C>T	p.R634W	Missense	13/21	-
17-7577030-C-A	TP53	c.908G>T	p.S303I	Missense	8/11	-
17-7578380-C-T	TP53	c.550G>A	p.D184N	Missense	5/11	-
17-7577102-C-A	TP53	c.836G>T	p.G279V	Missense	8/11	-
17-7578177-C-G	TP53	c.672G>C	p.E224D	Missense	6/11	-
17-7577135-T-C	TP53	c.803A>G	p.N268S	Missense	8/11	-
17-7578197-C-G	TP53	c.652G>C	p.V218L	Missense	6/11	-
17-7578238-T-C	TP53	c.611A>G	p.E204G	Missense	6/11	-
17-7578223-C-G	TP53	c.626G>C	p.R209T	Missense	6/11	-
17-7577542-T-C	TP53	c.739A>G	p.N247D	Missense	7/11	-
17-7577054-G-T	TP53	c.884C>A	p.P295H	Missense	8/11	-
17-7577112-C-A	TP53	c.826G>T	p.A276S	Missense	8/11	-
17-7578553-T-A	TP53	c.377A>T	p.Y126F	Missense	5/11	-
17-7578517-G-T	TP53	c.413C>A	p.A138D	Missense	5/11	-
17-7579457-G-T	TP53	c.230C>A	p.P77Q	Missense	4/11	-
17-7578548-G-A	TP53	c.382C>T	p.P128S	Missense	5/11	-
17-7577515-T-A	TP53	c.766A>T	p.T256S	Missense	7/11	-
12-25398269-C-T	KRAS	c.50G>A	p.S17N	Missense	2/5	-
17-7577578-T-C	TP53	c.703A>G	p.N235D	Missense	7/11	-
17-7579500-C-G	TP53	c.187G>C	p.A63P	Missense	4/11	-
17-7579400-G-C	TP53	c.287C>G	p.S96C	Missense	4/11	-
17-7578452-T-G	TP53	c.478A>C	p.M160L	Missense	5/11	-
7-140449164-C-T	BRAF	c.1915G>A	p.V639I	Missense	16/18	-
13-28919595-C-T	FLT1	c.2342G>A	p.R781Q	Missense	16/30	-
17-7578199-A-C	TP53	c.650T>G	p.V217G	Missense	6/11	-
5-67589138-G-C	PIK3R1	c.1126G>C	p.G376R	Missense	10/16	-
17-7576888-T-G	TP53	c.958A>C	p.K320Q	Missense	9/11	-
17-7579508-G-A	TP53	c.179C>T	p.P60L	Missense	4/11	-
17-7576887-T-C	TP53	c.959A>G	p.K320R	Missense	9/11	-
17-37881064-C-T	ERBB2	c.2393C>T	p.T798I	Missense	20/27	-
17-7577518-T-C	TP53	c.763A>G	p.I255V	Missense	7/11	-
17-7578256-T-C	TP53	c.593A>G	p.E198G	Missense	6/11	-
7-140481423-C-A	BRAF	c.1385G>T	p.R462I	Missense	11/18	-
7-140481433-C-G	BRAF	c.1375G>C	p.V459L	Missense	11/18	-
7-140481433-C-A	BRAF	c.1375G>T	p.V459L	Missense	11/18	-
3-178928080-A-C	PIK3CA	c.1358A>C	p.E453A	Missense	8/21	-
17-7579521-C-T	TP53	c.166G>A	p.E56K	Missense	4/11	-
17-7576857-A-T	TP53	c.989T>A	p.L330H	Missense	9/11	-
17-7579520-T-A	TP53	c.167A>T	p.E56V	Missense	4/11	-
17-7579446-T-C	TP53	c.241A>G	p.T81A	Missense	4/11	-
13-32912582-A-T	BRCA2	c.4090A>T	p.I1364L	Missense	11/27	-
7-55241615-T-C	EGFR	c.2063T>C	p.L688P	Missense	18/28	-
7-55241705-T-C	EGFR	c.2153T>C	p.L718P	Missense	18/28	-
17-7577088-T-C	TP53	c.850A>G	p.T284A	Missense	8/11	-
17-7577087-G-C	TP53	c.851C>G	p.T284R	Missense	8/11	-
17-7577563-T-A	TP53	c.718A>T	p.S240C	Missense	7/11	-
17-7578209-G-T	TP53	c.640C>A	p.H214N	Missense	6/11	-
17-7577049-G-T	TP53	c.889C>A	p.H297N	Missense	8/11	-
7-140476813-C-G	BRAF	c.1593G>C	p.W531C	Missense	13/18	-
7-55259458-C-T	EGFR	c.2516C>T	p.A839V	Missense	21/28	-
7-55259452-A-C	EGFR	c.2510A>C	p.D837A	Missense	21/28	-
7-55249113-A-G	EGFR	c.2411A>G	p.E804G	Missense	20/28	-
7-140549992-C-G	BRAF	c.159G>C	p.M53I	Missense	2/18	-
3-178952019-C-A	PIK3CA	c.3074C>A	p.T1025N	Missense	21/21	-
17-7578200-C-T	TP53	c.649G>A	p.V217M	Missense	6/11	-
17-7573984-A-G	TP53	c.1043T>C	p.L348S	Missense	10/11	-
17-7576854-T-G	TP53	c.992A>C	p.Q331P	Missense	9/11	-
17-7574015-A-T	TP53	c.1012T>A	p.F338I	Missense	10/11	-
17-7574033-T-C	TP53	c.994A>G	p.I332V	Missense	10/11	-
17-7576860-G-A	TP53	c.986C>T	p.T329I	Missense	9/11	-
17-7576867-A-C	TP53	c.979T>G	p.Y327D	Missense	9/11	-
17-7573961-C-A	TP53	c.1066G>T	p.G356W	Missense	10/11	-
17-7573960-C-G	TP53	c.1067G>C	p.G356A	Missense	10/11	-
17-7573980-T-A	TP53	c.1047A>T	p.E349D	Missense	10/11	-
17-7576867-A-G	TP53	c.979T>C	p.Y327H	Missense	9/11	-
17-7576866-T-G	TP53	c.980A>C	p.Y327S	Missense	9/11	-
17-7576869-T-C	TP53	c.977A>G	p.E326G	Missense	9/11	-
17-7574023-C-A	TP53	c.1004G>T	p.R335L	Missense	10/11	-
17-7573980-T-G	TP53	c.1047A>C	p.E349D	Missense	10/11	-
17-7574002-C-T	TP53	c.1025G>A	p.R342Q	Missense	10/11	-
17-7578380-C-A	TP53	c.550G>T	p.D184Y	Missense	5/11	-
17-7578188-C-G	TP53	c.661G>C	p.E221Q	Missense	6/11	-
17-7579707-T-C	TP53	c.89A>G	p.N30S	Missense	3/11	-
7-140501337-T-A	BRAF	c.735A>T	p.L245F	Missense	6/18	-
7-140477853-C-G	BRAF	c.1455G>C	p.L485F	Missense	12/18	-
7-140477811-T-G	BRAF	c.1497A>C	p.K499N	Missense	12/18	-
7-140453139-G-C	BRAF	c.1796C>G	p.T599R	Missense	15/18	-
7-140453134-T-G	BRAF	c.1801A>C	p.K601Q	Missense	15/18	-
17-7578440-T-G	TP53	c.490A>C	p.K164Q	Missense	5/11	-
7-140501249-C-T	BRAF	c.823G>A	p.E275K	Missense	6/18	-
17-37879903-C-T	ERBB2	c.2198C>T	p.T733I	Missense	18/27	-
17-37881392-A-G	ERBB2	c.2584A>G	p.T862A	Missense	21/27	-
17-7576858-G-A	TP53	c.988C>T	p.L330F	Missense	9/11	-
17-7573993-T-C	TP53	c.1034A>G	p.N345S	Missense	10/11	-
17-7574032-A-T	TP53	c.995T>A	p.I332N	Missense	10/11	-
17-7574032-A-C	TP53	c.995T>G	p.I332S	Missense	10/11	-
17-7576855-G-C	TP53	c.991C>G	p.Q331E	Missense	9/11	-
17-7577084-T-G	TP53	c.854A>C	p.E285A	Missense	8/11	-
17-7577024-T-C	TP53	c.914A>G	p.K305R	Missense	8/11	-
17-7579317-A-T	TP53	c.370T>A	p.C124S	Missense	4/11	-
17-7579316-C-G	TP53	c.371G>C	p.C124S	Missense	4/11	-
17-7578532-A-G	TP53	c.398T>C	p.M133T	Missense	5/11	-
17-7579322-A-G	TP53	c.365T>C	p.V122A	Missense	4/11	-
17-37866710-G-A	ERBB2	c.877G>A	p.A293T	Missense	7/27	-
7-128850838-G-A	SMO	c.1685G>A	p.R562Q	Missense	10/12	-
17-7576895-C-A	TP53	c.951G>T	p.Q317H	Missense	9/11	-
17-7576895-C-G	TP53	c.951G>C	p.Q317H	Missense	9/11	-
7-55259532-G-A	EGFR	c.2590G>A	p.A864T	Missense	21/28	-
17-7577129-A-T	TP53	c.809T>A	p.F270Y	Missense	8/11	-
12-112888158-C-G	PTPN11	c.174C>G	p.N58K	Missense	3/16	-
17-7579332-C-T	TP53	c.355G>A	p.A119T	Missense	4/11	-
17-7573990-T-C	TP53	c.1037A>G	p.E346G	Missense	10/11	-
17-7577113-A-C	TP53	c.825T>G	p.C275W	Missense	8/11	-
17-7579526-A-G	TP53	c.161T>C	p.F54S	Missense	4/11	-
17-7578242-C-T	TP53	c.607G>A	p.V203M	Missense	6/11	-
17-7578229-T-A	TP53	c.620A>T	p.D207V	Missense	6/11	-
17-7574008-A-T	TP53	c.1019T>A	p.M340K	Missense	10/11	-
17-7577063-T-C	TP53	c.875A>G	p.K292R	Missense	8/11	-
17-7577147-A-C	TP53	c.791T>G	p.L264R	Missense	8/11	-
7-140453167-C-T	BRAF	c.1768G>A	p.V590I	Missense	15/18	-
17-7578222-T-G	TP53	c.627A>C	p.R209S	Missense	6/11	-
17-7578401-G-T	TP53	c.529C>A	p.P177T	Missense	5/11	-
17-7579506-C-T	TP53	c.181G>A	p.D61N	Missense	4/11	-
7-140453130-G-A	BRAF	c.1805C>T	p.S602F	Missense	15/18	-
17-7578476-G-A	TP53	c.454C>T	p.P152S	Missense	5/11	-
17-7578222-T-A	TP53	c.627A>T	p.R209S	Missense	6/11	-
17-7577554-T-G	TP53	c.727A>C	p.M243L	Missense	7/11	-
17-7577554-T-A	TP53	c.727A>T	p.M243L	Missense	7/11	-
19-50905962-G-A	POLD1	c.934G>A	p.V312M	Missense	8/27	-
17-7577504-G-C	TP53	c.777C>G	p.D259E	Missense	7/11	-
17-7577504-G-T	TP53	c.777C>A	p.D259E	Missense	7/11	-
17-7573001-T-G	TP53	c.1108A>C	p.K370Q	Missense	11/11	-
17-7579317-A-G	TP53	c.370T>C	p.C124R	Missense	4/11	-
17-37880234-T-G	ERBB2	c.2278T>G	p.S760A	Missense	19/27	-
17-7578193-G-A	TP53	c.656C>T	p.P219L	Missense	6/11	-
17-7579841-T-G	TP53	c.72A>C	p.K24N	Missense	2/11	-
17-7579841-T-A	TP53	c.72A>T	p.K24N	Missense	2/11	-
17-7578396-G-C	TP53	c.534C>G	p.H178Q	Missense	5/11	-
17-7579317-A-C	TP53	c.370T>G	p.C124G	Missense	4/11	-
17-7579376-T-A	TP53	c.311A>T	p.Q104L	Missense	4/11	-
17-7578446-T-A	TP53	c.484A>T	p.I162F	Missense	5/11	-
7-140434507-G-A	BRAF	c.2191C>T	p.P731S	Missense	18/18	-
3-178948139-T-C	PIK3CA	c.2911T>C	p.C971R	Missense	20/21	-
7-140453137-C-G	BRAF	c.1798G>C	p.V600L	Missense	15/18	-
17-7578505-G-C	TP53	c.425C>G	p.P142R	Missense	5/11	-
3-178916957-G-T	PIK3CA	c.344G>T	p.R115L	Missense	2/21	-
3-178922319-G-C	PIK3CA	c.1088G>C	p.G363A	Missense	6/21	-
3-178948153-A-C	PIK3CA	c.2925A>C	p.R975S	Missense	20/21	-
3-178948153-A-T	PIK3CA	c.2925A>T	p.R975S	Missense	20/21	-
19-50905086-C-T	POLD1	c.368C>T	p.P123L	Missense	4/27	-
17-7579578-A-G	TP53	c.109T>C	p.S37P	Missense	4/11	-
3-178922376-G-A	PIK3CA	c.1145G>A	p.R382K	Missense	6/21	-
17-7578529-A-G	TP53	c.401T>C	p.F134S	Missense	5/11	-
3-178919167-G-A	PIK3CA	c.652G>A	p.E218K	Missense	4/21	-
3-178922297-G-A	PIK3CA	c.1066G>A	p.V356I	Missense	6/21	-
17-7579563-C-A	TP53	c.124G>T	p.D42Y	Missense	4/11	-
17-7578481-G-C	TP53	c.449C>G	p.T150R	Missense	5/11	-
17-7573978-A-G	TP53	c.1049T>C	p.L350P	Missense	10/11	-
17-7576886-C-G	TP53	c.960G>C	p.K320N	Missense	9/11	-
17-7577589-G-A	TP53	c.692C>T	p.T231I	Missense	7/11	-
17-7579449-G-A	TP53	c.238C>T	p.P80S	Missense	4/11	-
17-7579329-T-G	TP53	c.358A>C	p.K120Q	Missense	4/11	-
3-178916791-C-A	PIK3CA	c.178C>A	p.Q60K	Missense	2/21	-
17-7577587-T-A	TP53	c.694A>T	p.I232F	Missense	7/11	-
17-7577502-G-A	TP53	c.779C>T	p.S260F	Missense	7/11	-
17-7577039-G-A	TP53	c.899C>T	p.P300L	Missense	8/11	-
17-7579348-G-T	TP53	c.339C>A	p.F113L	Missense	4/11	-
17-7577608-C-T	TP53	c.673G>A	p.V225I	Missense	7/11	-
17-7577049-G-A	TP53	c.889C>T	p.H297Y	Missense	8/11	-
17-7577060-C-T	TP53	c.878G>A	p.G293E	Missense	8/11	-
17-7577499-C-T	TP53	c.782G>A	p.S261N	Missense	7/11	-
17-7579413-G-A	TP53	c.274C>T	p.P92S	Missense	4/11	-
17-7573952-G-A	TP53	c.1075C>T	p.P359S	Missense	10/11	-
17-7577604-C-T	TP53	c.677G>A	p.G226D	Missense	7/11	-
17-7577066-T-C	TP53	c.872A>G	p.K291R	Missense	8/11	-
17-7577033-C-T	TP53	c.905G>A	p.G302E	Missense	8/11	-
17-7577574-T-G	TP53	c.707A>C	p.Y236S	Missense	7/11	-
17-7574030-G-A	TP53	c.997C>T	p.R333C	Missense	10/11	-
17-7579508-G-T	TP53	c.179C>A	p.P60Q	Missense	4/11	-
19-50917108-C-T	POLD1	c.2360C>T	p.P787L	Missense	19/27	-
12-133242025-C-G	POLE	c.2331G>C	p.K777N	Missense	21/49	-
12-133250213-G-C	POLE	c.1307C>G	p.P436R	Missense	13/49	-
19-50918106-G-A	POLD1	c.2423G>A	p.R808H	Missense	20/27	-
12-133209349-C-T	POLE	c.6037G>A	p.D2013N	Missense	44/49	-
19-50909472-G-A	POLD1	c.1276G>A	p.G426S	Missense	11/27	-
19-50918720-G-A	POLD1	c.2590G>A	p.A864T	Missense	21/27	-
12-133244124-G-A	POLE	c.2284C>T	p.R762W	Missense	20/49	-
12-133218357-C-T	POLE	c.5254G>A	p.D1752N	Missense	39/49	-
12-133209065-C-T	POLE	c.6166G>A	p.A2056T	Missense	45/49	-
14-95560464-C-T	DICER1	c.5125G>A	p.D1709N	Missense	24/27	-
14-95560462-A-T	DICER1	c.5127T>A	p.D1709E	Missense	24/27	-
14-95557639-C-A	DICER1	c.5428G>T	p.D1810Y	Missense	25/27	-
12-133242025-C-A	POLE	c.2331G>T	p.K777N	Missense	21/49	-
17-7578266-T-G	TP53	c.583A>C	p.I195L	Missense	6/11	-
17-41243049-C-T	BRCA1	c.4097G>A	p.G1366D	Missense	11/23	-
2-198267360-T-A	SF3B1	c.1997A>T	p.K666M	Missense	14/25	-
17-7579544-T-C	TP53	c.143A>G	p.D48G	Missense	4/11	-
17-7579460-G-C	TP53	c.227C>G	p.A76G	Missense	4/11	-
17-7578187-T-G	TP53	c.662A>C	p.E221A	Missense	6/11	-
7-140453185-G-A	BRAF	c.1750C>T	p.L584F	Missense	15/18	-
17-7578419-C-T	TP53	c.511G>A	p.E171K	Missense	5/11	-
17-7578490-A-G	TP53	c.440T>C	p.V147A	Missense	5/11	-
17-7578551-A-C	TP53	c.379T>G	p.S127A	Missense	5/11	-
2-198267483-C-G	SF3B1	c.1874G>C	p.R625P	Missense	14/25	-
17-7576864-A-C	TP53	c.982T>G	p.F328V	Missense	9/11	-
7-140453115-G-A	BRAF	c.1820C>T	p.S607F	Missense	15/18	-
17-7573934-G-A	TP53	c.1093C>T	p.H365Y	Missense	10/11	-
11-17741694-T-G	MYOD1	c.365T>G	p.L122R	Missense	1/3	-
17-7578438-C-G	TP53	c.492G>C	p.K164N	Missense	5/11	-
17-7578438-C-A	TP53	c.492G>T	p.K164N	Missense	5/11	-
17-7578537-G-C	TP53	c.393C>G	p.N131K	Missense	5/11	-
17-7579445-G-A	TP53	c.242C>T	p.T81I	Missense	4/11	-
17-7578537-G-T	TP53	c.393C>A	p.N131K	Missense	5/11	-
17-7579554-G-T	TP53	c.133C>A	p.L45M	Missense	4/11	-
17-37881342-A-C	ERBB2	c.2534A>C	p.D845A	Missense	21/27	-
17-7579385-T-C	TP53	c.302A>G	p.K101R	Missense	4/11	-
4-55593592-A-G	KIT	c.1658A>G	p.Y553C	Missense	11/21	-
17-7576911-G-C	TP53	c.935C>G	p.T312S	Missense	9/11	-
17-7579461-C-T	TP53	c.226G>A	p.A76T	Missense	4/11	-
17-7578514-T-C	TP53	c.416A>G	p.K139R	Missense	5/11	-
17-7577562-C-T	TP53	c.719G>A	p.S240N	Missense	7/11	-
17-7577061-C-A	TP53	c.877G>T	p.G293W	Missense	8/11	-
12-25380247-A-G	KRAS	c.211T>C	p.Y71H	Missense	3/5	-
17-7578461-C-T	TP53	c.469G>A	p.V157I	Missense	5/11	-
12-133245032-A-C	POLE	c.2083T>G	p.F695V	Missense	19/49	-
12-133245032-A-G	POLE	c.2083T>C	p.F695L	Missense	19/49	-
12-133202816-C-G	POLE	c.6418G>C	p.E2140Q	Missense	46/49	-
12-133241911-G-T	POLE	c.2445C>A	p.F815L	Missense	21/49	-
12-133253217-T-A	POLE	c.824A>T	p.D275V	Missense	9/49	-
12-133250183-C-T	POLE	c.1337G>A	p.R446Q	Missense	13/49	-
19-50906786-G-A	POLD1	c.1174G>A	p.V392M	Missense	10/27	-
12-133234521-G-A	POLE	c.3311C>T	p.T1104M	Missense	27/49	-
12-133250189-A-T	POLE	c.1331T>A	p.M444K	Missense	13/49	-
17-7578389-G-T	TP53	c.541C>A	p.R181S	Missense	5/11	-
12-133250162-T-C	POLE	c.1358A>G	p.Q453R	Missense	13/49	-
12-133249829-G-A	POLE	c.1394C>T	p.A465V	Missense	14/49	-
17-7578194-G-A	TP53	c.655C>T	p.P219S	Missense	6/11	-
17-7577564-G-T	TP53	c.717C>A	p.N239K	Missense	7/11	-
17-7578245-G-A	TP53	c.604C>T	p.R202C	Missense	6/11	-
17-7578435-C-G	TP53	c.495G>C	p.Q165H	Missense	5/11	-
7-140453140-T-C	BRAF	c.1795A>G	p.T599A	Missense	15/18	-
13-32932063-A-G	BRCA2	c.7802A>G	p.Y2601C	Missense	16/27	-
14-95560475-T-G	DICER1	c.5114A>C	p.E1705A	Missense	24/27	-
17-7578242-C-G	TP53	c.607G>C	p.V203L	Missense	6/11	-
17-7579380-A-T	TP53	c.307T>A	p.Y103N	Missense	4/11	-
17-7577058-C-T	TP53	c.880G>A	p.E294K	Missense	8/11	-
17-7578242-C-A	TP53	c.607G>T	p.V203L	Missense	6/11	-
7-140453142-G-A	BRAF	c.1793C>T	p.A598V	Missense	15/18	-
17-7579362-A-C	TP53	c.325T>G	p.F109V	Missense	4/11	-
17-41267770-G-T	BRCA1	c.107C>A	p.S36Y	Missense	3/23	-
7-55241677-G-C	EGFR	c.2125G>C	p.E709Q	Missense	18/28	-
17-7579379-T-A	TP53	c.308A>T	p.Y103F	Missense	4/11	-
17-7579419-A-G	TP53	c.268T>C	p.S90P	Missense	4/11	-
17-7578423-C-T	TP53	c.507G>A	p.M169I	Missense	5/11	-
14-95569774-T-G	DICER1	c.3959A>C	p.D1320A	Missense	21/27	-
14-95562566-T-G	DICER1	c.4691A>C	p.E1564A	Missense	23/27	-
14-95560463-T-G	DICER1	c.5126A>C	p.D1709A	Missense	24/27	-
4-55593649-A-C	KIT	c.1715A>C	p.D572A	Missense	11/21	-
4-55589846-G-A	KIT	c.1328G>A	p.C443Y	Missense	8/21	-
12-133249841-G-A	POLE	c.1382C>T	p.S461L	Missense	14/49	-
12-133253182-C-T	POLE	c.859G>A	p.D287N	Missense	9/49	-
12-133252325-C-T	POLE	c.1102G>A	p.D368N	Missense	11/49	-
12-133250282-C-T	POLE	c.1238G>A	p.R413K	Missense	13/49	-
12-133250268-G-A	POLE	c.1252C>T	p.P418S	Missense	13/49	-
12-133250256-G-A	POLE	c.1264C>T	p.H422Y	Missense	13/49	-
12-133250250-G-A	POLE	c.1270C>T	p.L424F	Missense	13/49	-
12-133250198-G-A	POLE	c.1322C>T	p.P441L	Missense	13/49	-
12-133249784-G-A	POLE	c.1439C>T	p.A480V	Missense	14/49	-
17-7573967-G-T	TP53	c.1060C>A	p.Q354K	Missense	10/11	-
4-55593667-A-G	KIT	c.1733A>G	p.Y578C	Missense	11/21	-
17-7577064-T-C	TP53	c.874A>G	p.K292E	Missense	8/11	-
17-7578408-C-G	TP53	c.522G>C	p.R174S	Missense	5/11	-
17-7578520-A-G	TP53	c.410T>C	p.L137P	Missense	5/11	-
17-7577583-T-G	TP53	c.698A>C	p.H233P	Missense	7/11	-
17-7578408-C-A	TP53	c.522G>T	p.R174S	Missense	5/11	-
17-7578433-G-A	TP53	c.497C>T	p.S166L	Missense	5/11	-
17-7578249-A-C	TP53	c.600T>G	p.N200K	Missense	6/11	-
17-7578249-A-T	TP53	c.600T>A	p.N200K	Missense	6/11	-
7-55249062-A-G	EGFR	c.2360A>G	p.Q787R	Missense	20/28	-
17-37868201-G-A	ERBB2	c.922G>A	p.V308M	Missense	8/27	-
17-7578421-G-A	TP53	c.509C>T	p.T170M	Missense	5/11	-
17-37883158-G-C	ERBB2	c.3061G>C	p.E1021Q	Missense	25/27	-
17-7578277-G-C	TP53	c.572C>G	p.P191R	Missense	6/11	-
10-89720731-T-G	PTEN	c.882T>G	p.S294R	Missense	8/9	-
17-7579589-G-A	TP53	c.98C>T	p.S33F	Missense	4/11	-
17-7579882-C-T	TP53	c.31G>A	p.E11K	Missense	2/11	-
17-7578449-C-G	TP53	c.481G>C	p.A161P	Missense	5/11	-
17-7573996-A-T	TP53	c.1031T>A	p.L344Q	Missense	10/11	-
17-7577520-A-C	TP53	c.761T>G	p.I254S	Missense	7/11	-
3-178916891-G-C	PIK3CA	c.278G>C	p.R93P	Missense	2/21	-
17-7577067-T-C	TP53	c.871A>G	p.K291E	Missense	8/11	-
17-7577541-T-C	TP53	c.740A>G	p.N247S	Missense	7/11	-
17-7578475-G-C	TP53	c.455C>G	p.P152R	Missense	5/11	-
12-25378642-T-G	KRAS	c.356A>C	p.D119A	Missense	4/5	-
3-138383922-G-C	PIK3CB	c.2628C>G	p.F876L	Missense	20/24	-
3-138383922-G-T	PIK3CB	c.2628C>A	p.F876L	Missense	20/24	-
12-133248877-C-A	POLE	c.1718G>T	p.R573L	Missense	16/49	-
12-133201546-C-T	POLE	c.6692G>A	p.S2231N	Missense	48/49	-
17-7579353-C-T	TP53	c.334G>A	p.G112S	Missense	4/11	-
17-7579418-G-T	TP53	c.269C>A	p.S90Y	Missense	4/11	-
X-47430341-C-A	ARAF	c.1616C>A	p.P539H	Missense	15/16	-
17-7577595-C-A	TP53	c.686G>T	p.C229F	Missense	7/11	-
17-7573973-C-T	TP53	c.1054G>A	p.D352N	Missense	10/11	-
17-7574015-A-G	TP53	c.1012T>C	p.F338L	Missense	10/11	-
17-7574013-G-T	TP53	c.1014C>A	p.F338L	Missense	10/11	-
17-7574013-G-C	TP53	c.1014C>G	p.F338L	Missense	10/11	-
17-7576902-G-A	TP53	c.944C>T	p.S315F	Missense	9/11	-
19-50906319-C-G	POLD1	c.980C>G	p.P327R	Missense	9/27	-
17-7578513-C-A	TP53	c.417G>T	p.K139N	Missense	5/11	-
17-7578444-G-C	TP53	c.486C>G	p.I162M	Missense	5/11	-
17-7578289-C-T	TP53	c.560G>A	p.G187D	Missense	6/11	-
17-7578506-G-A	TP53	c.424C>T	p.P142S	Missense	5/11	-
17-7578511-G-A	TP53	c.419C>T	p.T140I	Missense	5/11	-
17-7578488-C-T	TP53	c.442G>A	p.D148N	Missense	5/11	-
17-7578226-T-C	TP53	c.623A>G	p.D208G	Missense	6/11	-
17-7577034-C-T	TP53	c.904G>A	p.G302R	Missense	8/11	-
17-7577034-C-G	TP53	c.904G>C	p.G302R	Missense	8/11	-
7-140501331-A-C	BRAF	c.741T>G	p.F247L	Missense	6/18	-
17-37879881-C-T	ERBB2	c.2176C>T	p.L726F	Missense	18/27	-
17-37884185-A-G	ERBB2	c.3656A>G	p.N1219S	Missense	27/27	-
7-140501333-A-G	BRAF	c.739T>C	p.F247L	Missense	6/18	-
10-89720823-T-G	PTEN	c.974T>G	p.L325R	Missense	8/9	-
13-32932066-G-C	BRCA2	c.7805G>C	p.R2602T	Missense	16/27	-
7-6426908-C-G	RAC1	c.101C>G	p.P34R	Missense	2/6	-
3-178916948-T-A	PIK3CA	c.335T>A	p.I112N	Missense	2/21	-
17-7578445-A-C	TP53	c.485T>G	p.I162S	Missense	5/11	-
17-7574000-C-T	TP53	c.1027G>A	p.E343K	Missense	10/11	-
17-7578220-T-C	TP53	c.629A>G	p.N210S	Missense	6/11	-
17-7578273-C-A	TP53	c.576G>T	p.Q192H	Missense	6/11	-
17-7578273-C-G	TP53	c.576G>C	p.Q192H	Missense	6/11	-
14-95557638-T-G	DICER1	c.5429A>C	p.D1810A	Missense	25/27	-
7-140481423-C-T	BRAF	c.1385G>A	p.R462K	Missense	11/18	-
9-21970989-A-T	CDKN2A	c.369T>A	p.H123Q	Missense	2/3	-
9-21970989-A-C	CDKN2A	c.369T>G	p.H123Q	Missense	2/3	-
7-55259494-T-C	EGFR	c.2552T>C	p.V851A	Missense	21/28	-
17-7577503-A-T	TP53	c.778T>A	p.S260T	Missense	7/11	-
17-7578472-G-T	TP53	c.458C>A	p.P153H	Missense	5/11	-
12-133250243-G-A	POLE	c.1277C>T	p.A426V	Missense	13/49	-
17-7579505-T-C	TP53	c.182A>G	p.D61G	Missense	4/11	-
7-128850335-G-A	SMO	c.1598G>A	p.S533N	Missense	9/12	-
12-133250184-G-A	POLE	c.1336C>T	p.R446W	Missense	13/49	-
17-7579421-G-A	TP53	c.266C>T	p.P89L	Missense	4/11	-
12-133253217-T-G	POLE	c.824A>C	p.D275A	Missense	9/49	-
19-50905960-G-A	POLD1	c.932G>A	p.R311H	Missense	8/27	-
17-7579463-G-A	TP53	c.224C>T	p.P75L	Missense	4/11	-
17-7577585-G-C	TP53	c.696C>G	p.I232M	Missense	7/11	-
17-7578215-A-T	TP53	c.634T>A	p.F212I	Missense	6/11	-
17-7577596-A-G	TP53	c.685T>C	p.C229R	Missense	7/11	-
17-7579582-C-A	TP53	c.105G>T	p.L35F	Missense	4/11	-
17-7579582-C-G	TP53	c.105G>C	p.L35F	Missense	4/11	-
12-133244184-G-A	POLE	c.2224C>T	p.R742C	Missense	20/49	-
12-133257249-G-A	POLE	c.229C>T	p.R77C	Missense	3/49	-
12-133241023-C-T	POLE	c.2494G>A	p.A832T	Missense	22/49	-
12-133250213-G-T	POLE	c.1307C>A	p.P436H	Missense	13/49	-
19-50910264-C-T	POLD1	c.1519C>T	p.R507C	Missense	13/27	-
19-50912082-C-A	POLD1	c.1816C>A	p.L606M	Missense	15/27	-
19-50905984-G-A	POLD1	c.956G>A	p.C319Y	Missense	8/27	-
19-50912441-G-A	POLD1	c.1955G>A	p.R652Q	Missense	16/27	-
12-133249842-A-G	POLE	c.1381T>C	p.S461P	Missense	14/49	-
17-7578190-T-A	TP53	c.659A>T	p.Y220F	Missense	6/11	-
17-7579394-G-T	TP53	c.293C>A	p.P98H	Missense	4/11	-
12-133237610-A-G	POLE	c.3005T>C	p.V1002A	Missense	25/49	-
3-178952004-C-T	PIK3CA	c.3059C>T	p.A1020V	Missense	21/21	-
17-7578385-C-T	TP53	c.545G>A	p.C182Y	Missense	5/11	-
17-7578269-G-C	TP53	c.580C>G	p.L194V	Missense	6/11	-
17-7572944-C-A	TP53	c.1165G>T	p.G389W	Missense	11/11	-
7-140507858-T-G	BRAF	c.613A>C	p.K205Q	Missense	5/18	-
7-140507788-T-A	BRAF	c.683A>T	p.E228V	Missense	5/18	-
17-7577132-C-T	TP53	c.806G>A	p.S269N	Missense	8/11	-
17-7578416-C-T	TP53	c.514G>A	p.V172I	Missense	5/11	-
17-7579436-G-A	TP53	c.251C>T	p.A84V	Missense	4/11	-
17-7577605-C-T	TP53	c.676G>A	p.G226S	Missense	7/11	-
7-55241647-C-T	EGFR	c.2095C>T	p.P699S	Missense	18/28	-
17-7577595-C-T	TP53	c.686G>A	p.C229Y	Missense	7/11	-
17-7577040-G-A	TP53	c.898C>T	p.P300S	Missense	8/11	-
17-7579481-G-A	TP53	c.206C>T	p.A69V	Missense	4/11	-
17-7578286-A-G	TP53	c.563T>C	p.L188P	Missense	6/11	-
10-89717727-G-T	PTEN	c.752G>T	p.G251V	Missense	7/9	-
7-55233016-C-T	EGFR	c.1766C>T	p.P589L	Missense	15/28	-
17-7579327-C-A	TP53	c.360G>T	p.K120N	Missense	4/11	-
17-7579327-C-G	TP53	c.360G>C	p.K120N	Missense	4/11	-
19-50909709-G-A	POLD1	c.1429G>A	p.V477M	Missense	12/27	-
7-55259419-A-G	EGFR	c.2477A>G	p.N826S	Missense	21/28	-
19-50906837-C-T	POLD1	c.1225C>T	p.R409W	Missense	10/27	-
7-128846405-T-C	SMO	c.1241T>C	p.V414A	Missense	6/12	-
12-133251992-G-C	POLE	c.1218C>G	p.D406E	Missense	12/49	-
17-7579418-G-A	TP53	c.269C>T	p.S90F	Missense	4/11	-
17-7578223-C-T	TP53	c.626G>A	p.R209K	Missense	6/11	-
17-37881010-C-T	ERBB2	c.2339C>T	p.P780L	Missense	20/27	-
17-37881024-C-T	ERBB2	c.2353C>T	p.L785F	Missense	20/27	-
17-37881018-T-C	ERBB2	c.2347T>C	p.S783P	Missense	20/27	-
17-7579716-G-A	TP53	c.80C>T	p.P27L	Missense	3/11	-
12-133250246-T-C	POLE	c.1274A>G	p.K425R	Missense	13/49	-
17-7572962-G-A	TP53	c.1147C>T	p.L383F	Missense	11/11	-
3-178916936-G-T	PIK3CA	c.323G>T	p.R108L	Missense	2/21	-
17-7578544-G-A	TP53	c.386C>T	p.A129V	Missense	5/11	-
17-7578181-G-T	TP53	c.668C>A	p.P223H	Missense	6/11	-
17-7573976-T-C	TP53	c.1051A>G	p.K351E	Missense	10/11	-
17-7578385-C-G	TP53	c.545G>C	p.C182S	Missense	5/11	-
17-7578386-A-T	TP53	c.544T>A	p.C182S	Missense	5/11	-
17-37881329-C-G	ERBB2	c.2521C>G	p.L841V	Missense	21/27	-
17-7579555-C-G	TP53	c.132G>C	p.M44I	Missense	4/11	-
17-7579555-C-T	TP53	c.132G>A	p.M44I	Missense	4/11	-
17-7579555-C-A	TP53	c.132G>T	p.M44I	Missense	4/11	-
17-7578241-A-T	TP53	c.608T>A	p.V203E	Missense	6/11	-
17-7577080-T-G	TP53	c.858A>C	p.E286D	Missense	8/11	-
17-7577597-G-C	TP53	c.684C>G	p.D228E	Missense	7/11	-
17-37868234-A-G	ERBB2	c.955A>G	p.N319D	Missense	8/27	-
17-7577080-T-A	TP53	c.858A>T	p.E286D	Missense	8/11	-
17-7577505-T-G	TP53	c.776A>C	p.D259A	Missense	7/11	-
17-7578218-T-G	TP53	c.631A>C	p.T211P	Missense	6/11	-
17-7577021-C-T	TP53	c.917G>A	p.R306Q	Missense	8/11	-
17-7578266-T-C	TP53	c.583A>G	p.I195V	Missense	6/11	-
17-7577154-C-T	TP53	c.784G>A	p.G262S	Missense	8/11	-
17-7577530-T-C	TP53	c.751A>G	p.I251V	Missense	7/11	-
7-55241656-G-T	EGFR	c.2104G>T	p.A702S	Missense	18/28	-
17-7577109-A-C	TP53	c.829T>G	p.C277G	Missense	8/11	-
12-133249752-C-T	POLE	c.1471G>A	p.E491K	Missense	14/49	-
17-7578274-T-A	TP53	c.575A>T	p.Q192L	Missense	6/11	-
17-7579373-C-G	TP53	c.314G>C	p.G105A	Missense	4/11	-
17-37881446-G-A	ERBB2	c.2638G>A	p.D880N	Missense	21/27	-
17-7577604-C-G	TP53	c.677G>C	p.G226A	Missense	7/11	-
17-7577109-A-G	TP53	c.829T>C	p.C277R	Missense	8/11	-
12-133210958-A-C	POLE	c.5818T>G	p.S1940A	Missense	43/49	-
12-133225520-G-A	POLE	c.4144C>T	p.R1382C	Missense	32/49	-
17-37882024-G-C	ERBB2	c.2790G>C	p.E930D	Missense	23/27	-
17-37882024-G-T	ERBB2	c.2790G>T	p.E930D	Missense	23/27	-
17-7577061-C-T	TP53	c.877G>A	p.G293R	Missense	8/11	-
17-7577521-T-G	TP53	c.760A>C	p.I254L	Missense	7/11	-
17-7577521-T-C	TP53	c.760A>G	p.I254V	Missense	7/11	-
7-128829152-G-A	SMO	c.160G>A	p.V54M	Missense	1/12	-
12-133226007-G-A	POLE	c.3890C>T	p.S1297L	Missense	31/49	-
19-50917005-T-C	POLD1	c.2257T>C	p.Y753H	Missense	19/27	-
17-7573994-T-C	TP53	c.1033A>G	p.N345D	Missense	10/11	-
17-37880988-G-A	ERBB2	c.2317G>A	p.V773M	Missense	20/27	-
17-7578473-G-A	TP53	c.457C>T	p.P153S	Missense	5/11	-
17-7578434-A-G	TP53	c.496T>C	p.S166P	Missense	5/11	-
17-7578219-G-C	TP53	c.630C>G	p.N210K	Missense	6/11	-
17-7578219-G-T	TP53	c.630C>A	p.N210K	Missense	6/11	-
17-7578377-T-A	TP53	c.553A>T	p.S185C	Missense	5/11	-
17-7578487-T-C	TP53	c.443A>G	p.D148G	Missense	5/11	-
17-7578488-C-A	TP53	c.442G>T	p.D148Y	Missense	5/11	-
17-7579368-A-G	TP53	c.319T>C	p.Y107H	Missense	4/11	-
17-7579464-G-A	TP53	c.223C>T	p.P75S	Missense	4/11	-
7-55221710-C-T	EGFR	c.754C>T	p.R252C	Missense	7/28	-
7-55249082-C-T	EGFR	c.2380C>T	p.P794S	Missense	20/28	-
17-41258516-C-A	BRCA1	c.169G>T	p.G57W	Missense	4/23	-
17-7578238-T-G	TP53	c.611A>C	p.E204A	Missense	6/11	-
17-7573955-C-T	TP53	c.1072G>A	p.E358K	Missense	10/11	-
17-7577599-C-G	TP53	c.682G>C	p.D228H	Missense	7/11	-
7-140482915-G-A	BRAF	c.1220C>T	p.P407L	Missense	10/18	-
12-133241912-A-G	POLE	c.2444T>C	p.F815S	Missense	21/49	-
7-140487360-G-A	BRAF	c.1165C>T	p.R389C	Missense	9/18	-
7-140453096-C-A	BRAF	c.1839G>T	p.L613F	Missense	15/18	-
5-67592114-G-T	PIK3R1	c.1930G>T	p.G644C	Missense	15/16	-
17-7578182-G-A	TP53	c.667C>T	p.P223S	Missense	6/11	-
17-7573988-C-G	TP53	c.1039G>C	p.A347P	Missense	10/11	-
17-7573936-G-A	TP53	c.1091C>T	p.A364V	Missense	10/11	-
17-7579404-A-G	TP53	c.283T>C	p.S95P	Missense	4/11	-
17-37884176-C-A	ERBB2	c.3647C>A	p.A1216D	Missense	27/27	-
17-7577512-G-C	TP53	c.769C>G	p.L257V	Missense	7/11	-
7-55241686-T-C	EGFR	c.2134T>C	p.F712L	Missense	18/28	-
7-55241688-C-A	EGFR	c.2136C>A	p.F712L	Missense	18/28	-
7-55241688-C-G	EGFR	c.2136C>G	p.F712L	Missense	18/28	-
12-133252382-C-T	POLE	c.1045G>A	p.E349K	Missense	11/49	-
17-37881410-C-T	ERBB2	c.2602C>T	p.R868W	Missense	21/27	-
19-50905358-C-A	POLD1	c.566C>A	p.A189D	Missense	5/27	-
19-50912885-G-A	POLD1	c.2116G>A	p.A706T	Missense	17/27	-
19-50906816-G-A	POLD1	c.1204G>A	p.D402N	Missense	10/27	-
12-133250250-G-T	POLE	c.1270C>A	p.L424I	Missense	13/49	-
17-7578502-A-T	TP53	c.428T>A	p.V143E	Missense	5/11	-
17-7578503-C-A	TP53	c.427G>T	p.V143L	Missense	5/11	-
7-140453182-G-A	BRAF	c.1753C>T	p.H585Y	Missense	15/18	-
12-133234500-C-T	POLE	c.3332G>A	p.R1111Q	Missense	27/49	-
12-133249803-C-T	POLE	c.1420G>A	p.V474I	Missense	14/49	-
12-133245072-G-C	POLE	c.2043C>G	p.S681R	Missense	19/49	-
12-133250214-G-A	POLE	c.1306C>T	p.P436S	Missense	13/49	-
12-133214612-T-C	POLE	c.5666A>G	p.Y1889C	Missense	41/49	-
12-133245072-G-T	POLE	c.2043C>A	p.S681R	Missense	19/49	-
12-133245074-T-G	POLE	c.2041A>C	p.S681R	Missense	19/49	-
12-133252386-C-A	POLE	c.1041G>T	p.W347C	Missense	11/49	-
5-180057563-A-G	FLT4	c.392T>C	p.F131S	Missense	3/30	-
17-7576891-T-C	TP53	c.955A>G	p.K319E	Missense	9/11	-
6-152265352-C-T	ESR1	c.805C>T	p.R269C	Missense	4/8	-
17-37872145-C-T	ERBB2	c.1466C>T	p.P489L	Missense	12/27	-
17-7579553-A-G	TP53	c.134T>C	p.L45P	Missense	4/11	-
3-138456596-C-T	PIK3CB	c.754G>A	p.G252R	Missense	6/24	-
12-25378643-C-T	KRAS	c.355G>A	p.D119N	Missense	4/5	-
19-50906845-G-C	POLD1	c.1233G>C	p.Q411H	Missense	10/27	-
19-50906845-G-T	POLD1	c.1233G>T	p.Q411H	Missense	10/27	-
12-133253139-T-C	POLE	c.902A>G	p.D301G	Missense	9/49	-
17-7578545-C-T	TP53	c.385G>A	p.A129T	Missense	5/11	-
17-7573982-C-T	TP53	c.1045G>A	p.E349K	Missense	10/11	-
12-133237644-C-G	POLE	c.2971G>C	p.E991Q	Missense	25/49	-
3-138374301-G-A	PIK3CB	c.3143C>T	p.A1048V	Missense	24/24	-
19-50912418-C-G	POLD1	c.1932C>G	p.D644E	Missense	16/27	-
19-50906847-C-T	POLD1	c.1235C>T	p.T412I	Missense	10/27	-
7-140453081-C-A	BRAF	c.1854G>T	p.L618F	Missense	15/18	-
17-7578523-T-G	TP53	c.407A>C	p.Q136P	Missense	5/11	-
17-7578553-T-G	TP53	c.377A>C	p.Y126S	Missense	5/11	-
17-7578522-T-G	TP53	c.408A>C	p.Q136H	Missense	5/11	-
17-7573999-T-G	TP53	c.1028A>C	p.E343A	Missense	10/11	-
17-37881583-C-T	ERBB2	c.2653C>T	p.P885S	Missense	22/27	-
7-140500260-G-T	BRAF	c.882C>A	p.F294L	Missense	7/18	-
17-7578229-T-C	TP53	c.620A>G	p.D207G	Missense	6/11	-
17-7573953-C-G	TP53	c.1074G>C	p.E358D	Missense	10/11	-
17-7573953-C-A	TP53	c.1074G>T	p.E358D	Missense	10/11	-
7-55233024-G-A	EGFR	c.1774G>A	p.V592I	Missense	15/28	-
17-7578251-T-A	TP53	c.598A>T	p.N200Y	Missense	6/11	-
17-7578544-G-T	TP53	c.386C>A	p.A129D	Missense	5/11	-
17-7578521-G-C	TP53	c.409C>G	p.L137V	Missense	5/11	-
17-7578257-C-T	TP53	c.592G>A	p.E198K	Missense	6/11	-
19-50916759-G-A	POLD1	c.2231G>A	p.G744D	Missense	18/27	-
17-7577602-A-G	TP53	c.679T>C	p.S227P	Missense	7/11	-
17-7578523-T-A	TP53	c.407A>T	p.Q136L	Missense	5/11	-
12-133226100-T-G	POLE	c.3797A>C	p.E1266A	Missense	31/49	-
3-138374298-A-C	PIK3CB	c.3146T>G	p.L1049R	Missense	24/24	-
17-7577587-T-C	TP53	c.694A>G	p.I232V	Missense	7/11	-
12-133254220-G-A	POLE	c.664C>T	p.R222C	Missense	7/49	-
12-133202758-C-T	POLE	c.6476G>A	p.R2159H	Missense	46/49	-
17-7577515-T-G	TP53	c.766A>C	p.T256P	Missense	7/11	-
12-133252748-C-T	POLE	c.952G>A	p.E318K	Missense	10/49	-
17-7577046-C-G	TP53	c.892G>C	p.E298Q	Missense	8/11	-
17-7576899-G-A	TP53	c.947C>T	p.P316L	Missense	9/11	-
17-7577021-C-G	TP53	c.917G>C	p.R306P	Missense	8/11	-
12-133201341-G-A	POLE	c.6803C>T	p.S2268L	Missense	49/49	-
12-133201369-G-A	POLE	c.6775C>T	p.R2259W	Missense	49/49	-
12-133201511-C-T	POLE	c.6727G>A	p.A2243T	Missense	48/49	-
12-133201520-C-T	POLE	c.6718G>A	p.G2240R	Missense	48/49	-
12-133201523-C-T	POLE	c.6715G>A	p.A2239T	Missense	48/49	-
12-133201562-C-T	POLE	c.6676G>A	p.G2226R	Missense	48/49	-
12-133201562-C-A	POLE	c.6676G>T	p.G2226W	Missense	48/49	-
12-133202283-G-A	POLE	c.6605C>T	p.T2202M	Missense	47/49	-
12-133202288-C-G	POLE	c.6600G>C	p.E2200D	Missense	47/49	-
12-133202290-C-T	POLE	c.6598G>A	p.E2200K	Missense	47/49	-
12-133202332-G-A	POLE	c.6556C>T	p.L2186F	Missense	47/49	-
12-133202349-G-A	POLE	c.6539C>T	p.A2180V	Missense	47/49	-
12-133202705-C-G	POLE	c.6529G>C	p.E2177Q	Missense	46/49	-
12-133236046-C-T	POLE	c.3110G>A	p.R1037H	Missense	26/49	-
12-133202782-T-C	POLE	c.6452A>G	p.Y2151C	Missense	46/49	-
12-133202713-G-A	POLE	c.6521C>T	p.S2174F	Missense	46/49	-
12-133202720-C-G	POLE	c.6514G>C	p.D2172H	Missense	46/49	-
12-133202738-C-A	POLE	c.6496G>T	p.D2166Y	Missense	46/49	-
12-133202738-C-T	POLE	c.6496G>A	p.D2166N	Missense	46/49	-
12-133202825-C-T	POLE	c.6409G>A	p.E2137K	Missense	46/49	-
12-133202828-C-T	POLE	c.6406G>A	p.G2136S	Missense	46/49	-
12-133202843-G-A	POLE	c.6391C>T	p.R2131C	Missense	46/49	-
12-133202870-C-T	POLE	c.6364G>A	p.V2122M	Missense	46/49	-
12-133208906-A-G	POLE	c.6325T>C	p.C2109R	Missense	45/49	-
12-133208909-C-A	POLE	c.6322G>T	p.V2108L	Missense	45/49	-
12-133208953-G-A	POLE	c.6278C>T	p.S2093F	Missense	45/49	-
12-133208960-G-A	POLE	c.6271C>T	p.P2091S	Missense	45/49	-
12-133208978-C-T	POLE	c.6253G>A	p.E2085K	Missense	45/49	-
12-133209024-C-A	POLE	c.6207G>T	p.K2069N	Missense	45/49	-
12-133209056-G-A	POLE	c.6175C>T	p.L2059F	Missense	45/49	-
12-133209267-G-A	POLE	c.6119C>T	p.A2040V	Missense	44/49	-
12-133209271-C-A	POLE	c.6115G>T	p.G2039W	Missense	44/49	-
12-133209298-C-T	POLE	c.6088G>A	p.A2030T	Missense	44/49	-
12-133209279-T-A	POLE	c.6107A>T	p.E2036V	Missense	44/49	-
12-133209285-G-A	POLE	c.6101C>T	p.S2034F	Missense	44/49	-
12-133209289-G-C	POLE	c.6097C>G	p.L2033V	Missense	44/49	-
12-133209295-T-C	POLE	c.6091A>G	p.S2031G	Missense	44/49	-
12-133209303-C-G	POLE	c.6083G>C	p.R2028T	Missense	44/49	-
12-133209315-G-A	POLE	c.6071C>T	p.P2024L	Missense	44/49	-
12-133209318-G-T	POLE	c.6068C>A	p.T2023N	Missense	44/49	-
12-133209319-T-C	POLE	c.6067A>G	p.T2023A	Missense	44/49	-
12-133209321-C-T	POLE	c.6065G>A	p.S2022N	Missense	44/49	-
12-133209328-G-C	POLE	c.6058C>G	p.P2020A	Missense	44/49	-
12-133209336-C-A	POLE	c.6050G>T	p.R2017L	Missense	44/49	-
15-99500633-G-A	IGF1R	c.4066G>A	p.E1356K	Missense	21/21	-
17-37884157-C-T	ERBB2	c.3628C>T	p.P1210S	Missense	27/27	-
17-37884229-C-T	ERBB2	c.3700C>T	p.P1234S	Missense	27/27	-
17-37884259-G-C	ERBB2	c.3730G>C	p.E1244Q	Missense	27/27	-
17-37884261-G-T	ERBB2	c.3732G>T	p.E1244D	Missense	27/27	-
17-7576908-C-T	TP53	c.938G>A	p.S313N	Missense	9/11	-
17-7572956-A-G	TP53	c.1153T>C	p.F385L	Missense	11/11	-
17-7576863-A-G	TP53	c.983T>C	p.F328S	Missense	9/11	-
17-7576870-C-T	TP53	c.976G>A	p.E326K	Missense	9/11	-
17-7576872-C-T	TP53	c.974G>A	p.G325E	Missense	9/11	-
17-7576872-C-G	TP53	c.974G>C	p.G325A	Missense	9/11	-
17-7576874-A-C	TP53	c.972T>G	p.D324E	Missense	9/11	-
17-7576874-A-T	TP53	c.972T>A	p.D324E	Missense	9/11	-
17-7576879-G-T	TP53	c.967C>A	p.L323M	Missense	9/11	-
17-7576879-G-C	TP53	c.967C>G	p.L323V	Missense	9/11	-
17-7576881-G-A	TP53	c.965C>T	p.P322L	Missense	9/11	-
17-7576889-C-A	TP53	c.957G>T	p.K319N	Missense	9/11	-
17-7576894-G-C	TP53	c.952C>G	p.P318A	Missense	9/11	-
17-7576896-T-G	TP53	c.950A>C	p.Q317P	Missense	9/11	-
17-7576897-G-T	TP53	c.949C>A	p.Q317K	Missense	9/11	-
17-7576902-G-C	TP53	c.944C>G	p.S315C	Missense	9/11	-
17-7576903-A-G	TP53	c.943T>C	p.S315P	Missense	9/11	-
17-7576909-T-A	TP53	c.937A>T	p.S313C	Missense	9/11	-
17-7576912-T-A	TP53	c.934A>T	p.T312S	Missense	9/11	-
17-7576917-T-G	TP53	c.929A>C	p.N310T	Missense	9/11	-
17-7576913-G-C	TP53	c.933C>G	p.N311K	Missense	9/11	-
17-7576915-T-G	TP53	c.931A>C	p.N311H	Missense	9/11	-
17-7577025-T-C	TP53	c.913A>G	p.K305E	Missense	8/11	-
9-98209328-T-C	PTCH1	c.4210A>G	p.T1404A	Missense	23/24	-
17-7577024-T-G	TP53	c.914A>C	p.K305T	Missense	8/11	-
4-55161371-G-A	PDGFRA	c.3202G>A	p.E1068K	Missense	23/23	-
7-128852114-C-T	SMO	c.2186C>T	p.A729V	Missense	12/12	-
12-133256784-A-G	POLE	c.310T>C	p.F104L	Missense	4/49	-
3-12645693-G-C	RAF1	c.776C>G	p.S259C	Missense	7/17	-
7-140534429-G-A	BRAF	c.484C>T	p.P162S	Missense	3/18	-
12-133249839-C-A	POLE	c.1384G>T	p.D462Y	Missense	14/49	-
17-37881333-T-A	ERBB2	c.2525T>A	p.V842E	Missense	21/27	-
12-133245459-G-A	POLE	c.1861C>T	p.L621F	Missense	17/49	-
17-7578223-C-A	TP53	c.626G>T	p.R209I	Missense	6/11	-
17-7579488-G-A	TP53	c.199C>T	p.P67S	Missense	4/11	-
17-7578513-C-G	TP53	c.417G>C	p.K139N	Missense	5/11	-
17-7577524-T-G	TP53	c.757A>C	p.T253P	Missense	7/11	-
17-7577084-T-C	TP53	c.854A>G	p.E285G	Missense	8/11	-
17-7578445-A-G	TP53	c.485T>C	p.I162T	Missense	5/11	-
17-7577584-G-A	TP53	c.697C>T	p.H233Y	Missense	7/11	-
17-7577580-T-A	TP53	c.701A>T	p.Y234F	Missense	7/11	-
12-133241897-A-G	POLE	c.2459T>C	p.M820T	Missense	21/49	-
12-133256782-G-T	POLE	c.312C>A	p.F104L	Missense	4/49	-
12-133256782-G-C	POLE	c.312C>G	p.F104L	Missense	4/49	-
12-133256805-C-T	POLE	c.289G>A	p.A97T	Missense	4/49	-
17-7577090-C-A	TP53	c.848G>T	p.R283L	Missense	8/11	-
13-32944693-A-G	BRCA2	c.8486A>G	p.Q2829R	Missense	19/27	-
17-41246553-C-T	BRCA1	c.995G>A	p.R332Q	Missense	10/23	-
19-50912814-G-A	POLD1	c.2045G>A	p.R682Q	Missense	17/27	-
12-133249827-T-C	POLE	c.1396A>G	p.T466A	Missense	14/49	-
19-50909556-C-T	POLD1	c.1360C>T	p.R454C	Missense	11/27	-
12-133218405-C-T	POLE	c.5206G>A	p.V1736I	Missense	39/49	-
12-133202768-C-T	POLE	c.6466G>A	p.V2156I	Missense	46/49	-
12-133220545-G-A	POLE	c.4168C>T	p.R1390C	Missense	33/49	-
7-55214316-G-A	EGFR	c.442G>A	p.V148M	Missense	4/28	-
2-29455179-C-T	ALK	c.2623G>A	p.G875R	Missense	15/29	-
2-29455179-C-G	ALK	c.2623G>C	p.G875R	Missense	15/29	-
19-50910642-C-T	POLD1	c.1745C>T	p.T582M	Missense	14/27	-
12-133220026-G-A	POLE	c.4411C>T	p.R1471C	Missense	34/49	-
17-7577598-T-G	TP53	c.683A>C	p.D228A	Missense	7/11	-
17-7577601-G-A	TP53	c.680C>T	p.S227F	Missense	7/11	-
17-7577136-T-G	TP53	c.802A>C	p.N268H	Missense	8/11	-
17-7579407-A-T	TP53	c.280T>A	p.S94T	Missense	4/11	-
17-7578244-C-G	TP53	c.605G>C	p.R202P	Missense	6/11	-
19-50920445-C-T	POLD1	c.3137C>T	p.A1046V	Missense	26/27	-
12-133219832-G-A	POLE	c.4529C>T	p.A1510V	Missense	35/49	-
17-7577533-G-C	TP53	c.748C>G	p.P250A	Missense	7/11	-
17-7578423-C-A	TP53	c.507G>T	p.M169I	Missense	5/11	-
17-7577030-C-G	TP53	c.908G>C	p.S303T	Missense	8/11	-
17-7578375-G-T	TP53	c.555C>A	p.S185R	Missense	5/11	-
17-7579458-G-C	TP53	c.229C>G	p.P77A	Missense	4/11	-
17-7578200-C-A	TP53	c.649G>T	p.V217L	Missense	6/11	-
17-7577063-T-G	TP53	c.875A>C	p.K292T	Missense	8/11	-
17-7577582-G-C	TP53	c.699C>G	p.H233Q	Missense	7/11	-
17-7578277-G-A	TP53	c.572C>T	p.P191L	Missense	6/11	-
17-7577599-C-T	TP53	c.682G>A	p.D228N	Missense	7/11	-
17-7577604-C-A	TP53	c.677G>T	p.G226V	Missense	7/11	-
17-7578259-A-T	TP53	c.590T>A	p.V197E	Missense	6/11	-
17-7578425-T-C	TP53	c.505A>G	p.M169V	Missense	5/11	-
17-7577125-C-G	TP53	c.813G>C	p.E271D	Missense	8/11	-
17-7577553-A-C	TP53	c.728T>G	p.M243R	Missense	7/11	-
17-7577075-T-C	TP53	c.863A>G	p.N288S	Missense	8/11	-
19-50919960-G-A	POLD1	c.3047G>A	p.R1016H	Missense	24/27	-
17-7578386-A-G	TP53	c.544T>C	p.C182R	Missense	5/11	-
17-7577031-T-A	TP53	c.907A>T	p.S303C	Missense	8/11	-
17-7578217-G-T	TP53	c.632C>A	p.T211N	Missense	6/11	-
17-7578377-T-C	TP53	c.553A>G	p.S185G	Missense	5/11	-
17-7578470-C-A	TP53	c.460G>T	p.G154C	Missense	5/11	-
17-7577078-T-C	TP53	c.860A>G	p.E287G	Missense	8/11	-
17-7577055-G-A	TP53	c.883C>T	p.P295S	Missense	8/11	-
17-7578476-G-C	TP53	c.454C>G	p.P152A	Missense	5/11	-
17-7578374-C-G	TP53	c.556G>C	p.D186H	Missense	5/11	-
17-7578439-T-A	TP53	c.491A>T	p.K164M	Missense	5/11	-
17-7578194-G-T	TP53	c.655C>A	p.P219T	Missense	6/11	-
17-7577562-C-G	TP53	c.719G>C	p.S240T	Missense	7/11	-
17-7578199-A-G	TP53	c.650T>C	p.V217A	Missense	6/11	-
17-7577027-G-A	TP53	c.911C>T	p.T304I	Missense	8/11	-
17-7577578-T-A	TP53	c.703A>T	p.N235Y	Missense	7/11	-
17-7577599-C-A	TP53	c.682G>T	p.D228Y	Missense	7/11	-
12-133218865-G-A	POLE	c.5071C>T	p.R1691C	Missense	38/49	-
19-50918141-G-A	POLD1	c.2458G>A	p.A820T	Missense	20/27	-
17-7579454-G-A	TP53	c.233C>T	p.A78V	Missense	4/11	-
17-7578289-C-A	TP53	c.560G>T	p.G187V	Missense	6/11	-
17-7577133-T-A	TP53	c.805A>T	p.S269C	Missense	8/11	-
17-7578371-C-A	TP53	c.559G>T	p.G187C	Missense	5/11	-
17-7579470-C-G	TP53	c.217G>C	p.V73L	Missense	4/11	-
17-7578523-T-C	TP53	c.407A>G	p.Q136R	Missense	5/11	-
17-7577052-G-T	TP53	c.886C>A	p.H296N	Missense	8/11	-
17-7578430-T-A	TP53	c.500A>T	p.Q167L	Missense	5/11	-
17-7577145-G-T	TP53	c.793C>A	p.L265M	Missense	8/11	-
17-7578257-C-G	TP53	c.592G>C	p.E198Q	Missense	6/11	-
17-7577141-C-G	TP53	c.797G>C	p.G266A	Missense	8/11	-
17-7578246-C-A	TP53	c.603G>T	p.L201F	Missense	6/11	-
17-7578246-C-G	TP53	c.603G>C	p.L201F	Missense	6/11	-
17-7577132-C-G	TP53	c.806G>C	p.S269T	Missense	8/11	-
17-7577056-C-A	TP53	c.882G>T	p.E294D	Missense	8/11	-
17-7573966-T-C	TP53	c.1061A>G	p.Q354R	Missense	10/11	-
17-7577062-T-G	TP53	c.876A>C	p.K292N	Missense	8/11	-
17-7577577-T-G	TP53	c.704A>C	p.N235T	Missense	7/11	-
17-7577540-G-T	TP53	c.741C>A	p.N247K	Missense	7/11	-
17-7578409-C-A	TP53	c.521G>T	p.R174M	Missense	5/11	-
17-7577091-G-C	TP53	c.847C>G	p.R283G	Missense	8/11	-
17-7578250-T-A	TP53	c.599A>T	p.N200I	Missense	6/11	-
17-7578396-G-T	TP53	c.534C>A	p.H178Q	Missense	5/11	-
17-7579463-G-C	TP53	c.224C>G	p.P75R	Missense	4/11	-
12-133256186-T-C	POLE	c.475A>G	p.T159A	Missense	6/49	-
17-7578463-C-A	TP53	c.467G>T	p.R156L	Missense	5/11	-
17-7578284-C-T	TP53	c.565G>A	p.A189T	Missense	6/11	-
17-7579427-G-T	TP53	c.260C>A	p.P87Q	Missense	4/11	-
17-7577541-T-G	TP53	c.740A>C	p.N247T	Missense	7/11	-
17-7577103-C-A	TP53	c.835G>T	p.G279W	Missense	8/11	-
17-7578464-G-T	TP53	c.466C>A	p.R156S	Missense	5/11	-
17-7577592-G-T	TP53	c.689C>A	p.T230N	Missense	7/11	-
17-7578424-A-G	TP53	c.506T>C	p.M169T	Missense	5/11	-
17-7578278-G-A	TP53	c.571C>T	p.P191S	Missense	6/11	-
12-133241993-G-A	POLE	c.2363C>T	p.A788V	Missense	21/49	-
19-50906769-G-A	POLD1	c.1157G>A	p.R386H	Missense	10/27	-
12-133257828-G-A	POLE	c.100C>T	p.R34C	Missense	2/49	-
12-133252337-C-T	POLE	c.1090G>A	p.G364R	Missense	11/49	-
3-30713801-G-A	TGFBR2	c.1126G>A	p.V376M	Missense	4/7	-
17-7579569-T-G	TP53	c.118A>C	p.M40L	Missense	4/11	-
19-50909523-C-T	POLD1	c.1327C>T	p.R443W	Missense	11/27	-
9-21971060-C-A	CDKN2A	c.298G>T	p.A100S	Missense	2/3	-
19-50902685-T-C	POLD1	c.260T>C	p.L87P	Missense	3/27	-
19-50919935-C-T	POLD1	c.3022C>T	p.R1008C	Missense	24/27	-
17-7577042-A-G	TP53	c.896T>C	p.L299P	Missense	8/11	-
17-7579481-G-T	TP53	c.206C>A	p.A69D	Missense	4/11	-
7-55221711-G-C	EGFR	c.755G>C	p.R252P	Missense	7/28	-
5-67591086-A-G	PIK3R1	c.1679A>G	p.D560G	Missense	13/16	-
12-133219848-G-A	POLE	c.4513C>T	p.P1505S	Missense	35/49	-
17-7578506-G-C	TP53	c.424C>G	p.P142A	Missense	5/11	-
17-7579569-T-A	TP53	c.118A>T	p.M40L	Missense	4/11	-
17-7578227-C-G	TP53	c.622G>C	p.D208H	Missense	6/11	-
19-50905993-G-A	POLD1	c.965G>A	p.R322H	Missense	8/27	-
12-133253208-G-A	POLE	c.833C>T	p.T278M	Missense	9/49	-
12-133226032-G-A	POLE	c.3865C>T	p.R1289C	Missense	31/49	-
12-133215825-T-C	POLE	c.5438A>G	p.Y1813C	Missense	40/49	-
12-133226461-C-G	POLE	c.3597G>C	p.E1199D	Missense	30/49	-
12-133226406-C-T	POLE	c.3652G>A	p.V1218I	Missense	30/49	-
12-133226460-C-T	POLE	c.3598G>A	p.A1200T	Missense	30/49	-
12-133234001-G-C	POLE	c.3393C>G	p.D1131E	Missense	28/49	-
12-133234001-G-T	POLE	c.3393C>A	p.D1131E	Missense	28/49	-
12-133249302-C-T	POLE	c.1597G>A	p.V533M	Missense	15/49	-
12-133219167-C-T	POLE	c.4877G>A	p.R1626H	Missense	37/49	-
12-133256588-C-G	POLE	c.375G>C	p.Q125H	Missense	5/49	-
12-133226461-C-A	POLE	c.3597G>T	p.E1199D	Missense	30/49	-
12-133256588-C-A	POLE	c.375G>T	p.Q125H	Missense	5/49	-
7-55259500-T-C	EGFR	c.2558T>C	p.I853T	Missense	21/28	-
5-67590478-C-T	PIK3R1	c.1540C>T	p.R514C	Missense	12/16	-
19-50905464-A-G	POLD1	c.592A>G	p.M198V	Missense	6/27	-
19-50905312-C-T	POLD1	c.520C>T	p.R174W	Missense	5/27	-
19-50909745-G-A	POLD1	c.1465G>A	p.V489M	Missense	12/27	-
12-133257730-C-T	POLE	c.198G>A	p.M66I	Missense	2/49	-
12-133245464-C-T	POLE	c.1856G>A	p.C619Y	Missense	17/49	-
14-95560462-A-C	DICER1	c.5127T>G	p.D1709E	Missense	24/27	-
19-50920504-C-T	POLD1	c.3196C>T	p.H1066Y	Missense	26/27	-
17-7578442-T-A	TP53	c.488A>T	p.Y163F	Missense	5/11	-
12-133219468-G-A	POLE	c.4666C>T	p.R1556W	Missense	36/49	-
12-133233786-T-C	POLE	c.3518A>G	p.E1173G	Missense	29/49	-
12-133220557-G-A	POLE	c.4156C>T	p.R1386W	Missense	33/49	-
12-133233825-C-T	POLE	c.3479G>A	p.R1160H	Missense	29/49	-
12-133240684-C-G	POLE	c.2612G>C	p.S871T	Missense	23/49	-
12-133215868-C-T	POLE	c.5395G>A	p.V1799I	Missense	40/49	-
12-133218299-G-A	POLE	c.5312C>T	p.T1771M	Missense	39/49	-
19-50910337-A-G	POLD1	c.1592A>G	p.N531S	Missense	13/27	-
17-7578544-G-C	TP53	c.386C>G	p.A129G	Missense	5/11	-
19-50905324-G-A	POLD1	c.532G>A	p.G178R	Missense	5/27	-
19-50905324-G-C	POLD1	c.532G>C	p.G178R	Missense	5/27	-
12-133252403-G-A	POLE	c.1024C>T	p.H342Y	Missense	11/49	-
17-7579398-C-T	TP53	c.289G>A	p.V97I	Missense	4/11	-
1-16464489-C-G	EPHA2	c.1171G>C	p.G391R	Missense	5/17	-
12-133225637-C-T	POLE	c.4027G>A	p.G1343S	Missense	32/49	-
12-133226406-C-G	POLE	c.3652G>C	p.V1218L	Missense	30/49	-
12-133225892-C-A	POLE	c.4005G>T	p.Q1335H	Missense	31/49	-
12-133225892-C-G	POLE	c.4005G>C	p.Q1335H	Missense	31/49	-
17-7579350-A-T	TP53	c.337T>A	p.F113I	Missense	4/11	-
1-9783217-C-T	PIK3CD	c.2461C>T	p.R821C	Missense	20/24	-
8-38282161-C-A	FGFR1	c.802G>T	p.A268S	Missense	7/18	-
17-7579500-C-T	TP53	c.187G>A	p.A63T	Missense	4/11	-
17-41244524-C-A	BRCA1	c.3024G>T	p.M1008I	Missense	10/23	-
17-7577051-T-G	TP53	c.887A>C	p.H296P	Missense	8/11	-
19-50906393-C-T	POLD1	c.1054C>T	p.R352C	Missense	9/27	-
19-50909688-C-T	POLD1	c.1408C>T	p.R470C	Missense	12/27	-
12-133218916-C-T	POLE	c.5020G>A	p.A1674T	Missense	38/49	-
12-133249755-C-A	POLE	c.1468G>T	p.D490Y	Missense	14/49	-
12-133245231-C-A	POLE	c.2016G>T	p.R672S	Missense	18/49	-
17-7579369-G-T	TP53	c.318C>A	p.S106R	Missense	4/11	-
17-7579371-T-G	TP53	c.316A>C	p.S106R	Missense	4/11	-
17-7578423-C-G	TP53	c.507G>C	p.M169I	Missense	5/11	-
17-7578239-C-G	TP53	c.610G>C	p.E204Q	Missense	6/11	-
17-7574018-G-T	TP53	c.1009C>A	p.R337S	Missense	10/11	-
17-7578493-C-G	TP53	c.437G>C	p.W146S	Missense	5/11	-
7-55223543-C-T	EGFR	c.910C>T	p.H304Y	Missense	8/28	-
7-140434525-G-A	BRAF	c.2173C>T	p.H725Y	Missense	18/18	-
18-48593557-G-C	SMAD4	c.1308G>C	p.K436N	Missense	10/12	-
18-48593557-G-T	SMAD4	c.1308G>T	p.K436N	Missense	10/12	-
17-37866359-G-T	ERBB2	c.664G>T	p.G222C	Missense	6/27	-
17-37879613-T-C	ERBB2	c.1988T>C	p.L663P	Missense	17/27	-
17-37864650-T-G	ERBB2	c.302T>G	p.I101S	Missense	3/27	-
17-37866671-G-A	ERBB2	c.838G>A	p.E280K	Missense	7/27	-
17-37864760-C-T	ERBB2	c.412C>T	p.R138W	Missense	3/27	-
17-37872839-C-T	ERBB2	c.1718C>T	p.S573L	Missense	14/27	-
7-140494149-G-A	BRAF	c.1099C>T	p.P367S	Missense	8/18	-
7-55210002-C-G	EGFR	c.112C>G	p.L38V	Missense	2/28	-
7-55223567-G-T	EGFR	c.934G>T	p.G312W	Missense	8/28	-
7-140494110-C-G	BRAF	c.1138G>C	p.D380H	Missense	8/18	-
7-140453108-C-A	BRAF	c.1827G>T	p.Q609H	Missense	15/18	-
7-140453108-C-G	BRAF	c.1827G>C	p.Q609H	Missense	15/18	-
17-7579451-G-A	TP53	c.236C>T	p.A79V	Missense	4/11	-
17-37880207-G-A	ERBB2	c.2251G>A	p.A751T	Missense	19/27	-
17-37881620-G-A	ERBB2	c.2690G>A	p.R897Q	Missense	22/27	-
17-37868196-C-T	ERBB2	c.917C>T	p.T306M	Missense	8/27	-
17-37884261-G-C	ERBB2	c.3732G>C	p.E1244D	Missense	27/27	-
7-55221744-C-T	EGFR	c.788C>T	p.T263I	Missense	7/28	-
7-55273168-A-G	EGFR	c.3491A>G	p.Q1164R	Missense	28/28	-
7-55227956-A-G	EGFR	c.1423A>G	p.I475V	Missense	12/28	-
17-7579375-C-A	TP53	c.312G>T	p.Q104H	Missense	4/11	-
7-140449137-C-G	BRAF	c.1942G>C	p.E648Q	Missense	16/18	-
7-140494206-G-T	BRAF	c.1042C>A	p.P348T	Missense	8/18	-
7-140453110-G-C	BRAF	c.1825C>G	p.Q609E	Missense	15/18	-
7-140501337-T-G	BRAF	c.735A>C	p.L245F	Missense	6/18	-
17-7579375-C-G	TP53	c.312G>C	p.Q104H	Missense	4/11	-
7-55224337-C-A	EGFR	c.1118C>A	p.P373Q	Missense	9/28	-
7-55233123-A-G	EGFR	c.1873A>G	p.T625A	Missense	15/28	-
7-55268881-G-A	EGFR	c.2947G>A	p.G983R	Missense	25/28	-
7-55268881-G-C	EGFR	c.2947G>C	p.G983R	Missense	25/28	-
7-55268060-A-C	EGFR	c.2900A>C	p.E967A	Missense	24/28	-
7-55221771-C-T	EGFR	c.815C>T	p.P272L	Missense	7/28	-
7-55211104-C-T	EGFR	c.347C>T	p.S116F	Missense	3/28	-
17-7577138-C-A	TP53	c.800G>T	p.R267L	Missense	8/11	-
7-140501260-C-T	BRAF	c.812G>A	p.R271H	Missense	6/18	-
7-140482879-G-T	BRAF	c.1256C>A	p.S419Y	Missense	10/18	-
7-55221830-G-A	EGFR	c.874G>A	p.V292M	Missense	7/28	-
7-55242439-A-G	EGFR	c.2209A>G	p.K737E	Missense	19/28	-
7-55241648-C-T	EGFR	c.2096C>T	p.P699L	Missense	18/28	-
7-55219021-C-G	EGFR	c.594C>G	p.S198R	Missense	5/28	-
7-55219021-C-A	EGFR	c.594C>A	p.S198R	Missense	5/28	-
7-55219019-A-C	EGFR	c.592A>C	p.S198R	Missense	5/28	-
7-140501299-C-A	BRAF	c.773G>T	p.G258V	Missense	6/18	-
7-140482933-G-A	BRAF	c.1202C>T	p.T401I	Missense	10/18	-
7-140439707-G-T	BRAF	c.2032C>A	p.L678I	Missense	17/18	-
7-140549961-G-T	BRAF	c.190C>A	p.L64I	Missense	2/18	-
7-55227864-A-G	EGFR	c.1331A>G	p.N444S	Missense	12/28	-
17-37883113-C-T	ERBB2	c.3016C>T	p.R1006C	Missense	25/27	-
3-178916935-C-T	PIK3CA	c.322C>T	p.R108C	Missense	2/21	-
3-178928074-G-T	PIK3CA	c.1352G>T	p.G451V	Missense	8/21	-
17-7579424-G-A	TP53	c.263C>T	p.A88V	Missense	4/11	-
17-7579479-C-T	TP53	c.208G>A	p.A70T	Missense	4/11	-
3-178916645-G-T	PIK3CA	c.32G>T	p.W11L	Missense	2/21	-
12-25362828-G-T	KRAS	c.468C>A	p.F156L	Missense	5/5	-
17-7577136-T-A	TP53	c.802A>T	p.N268Y	Missense	8/11	-
17-7578237-C-G	TP53	c.612G>C	p.E204D	Missense	6/11	-
17-7579350-A-G	TP53	c.337T>C	p.F113L	Missense	4/11	-
17-7579348-G-C	TP53	c.339C>G	p.F113L	Missense	4/11	-
17-7578237-C-A	TP53	c.612G>T	p.E204D	Missense	6/11	-
5-67589168-C-G	PIK3R1	c.1156C>G	p.R386G	Missense	10/16	-
17-7579365-C-A	TP53	c.322G>T	p.G108C	Missense	4/11	-
17-7579482-C-T	TP53	c.205G>A	p.A69T	Missense	4/11	-
17-7578178-T-C	TP53	c.671A>G	p.E224G	Missense	6/11	-
17-7576885-T-C	TP53	c.961A>G	p.K321E	Missense	9/11	-
17-7579580-G-A	TP53	c.107C>T	p.P36L	Missense	4/11	-
12-133245011-C-T	POLE	c.2104G>A	p.G702R	Missense	19/49	-
17-7573954-T-A	TP53	c.1073A>T	p.E358V	Missense	10/11	-
12-133249419-G-A	POLE	c.1480C>T	p.R494W	Missense	15/49	-
19-50905097-G-A	POLD1	c.379G>A	p.A127T	Missense	4/27	-
12-133226355-G-T	POLE	c.3703C>A	p.L1235I	Missense	30/49	-
17-37866434-C-T	ERBB2	c.739C>T	p.P247S	Missense	6/27	-
7-140434413-G-A	BRAF	c.2285C>T	p.A762V	Missense	18/18	-
12-133215787-G-A	POLE	c.5476C>T	p.R1826W	Missense	40/49	-
19-50917071-G-A	POLD1	c.2323G>A	p.G775R	Missense	19/27	-
12-133234487-C-A	POLE	c.3345G>T	p.K1115N	Missense	27/49	-
19-50905543-G-A	POLD1	c.671G>A	p.R224H	Missense	6/27	-
19-50905537-C-T	POLD1	c.665C>T	p.P222L	Missense	6/27	-
12-133249835-G-A	POLE	c.1388C>T	p.A463V	Missense	14/49	-
12-133220143-G-A	POLE	c.4294C>T	p.P1432S	Missense	34/49	-
12-133241895-G-A	POLE	c.2461C>T	p.R821C	Missense	21/49	-
19-50902682-C-T	POLD1	c.257C>T	p.A86V	Missense	3/27	-
19-50910630-G-A	POLD1	c.1733G>A	p.G578D	Missense	14/27	-
4-1806185-C-T	FGFR3	c.1204C>T	p.P402S	Missense	9/18	-
12-133234549-G-A	POLE	c.3283C>T	p.P1095S	Missense	27/49	-
17-41246793-C-T	BRCA1	c.755G>A	p.R252H	Missense	10/23	-
12-133241030-C-G	POLE	c.2487G>C	p.M829I	Missense	22/49	-
12-133241030-C-T	POLE	c.2487G>A	p.M829I	Missense	22/49	-
12-133241030-C-A	POLE	c.2487G>T	p.M829I	Missense	22/49	-
3-138453486-C-T	PIK3CB	c.962G>A	p.R321Q	Missense	7/24	-
4-55144623-G-T	PDGFRA	c.2097G>T	p.E699D	Missense	15/23	-
12-133233946-C-T	POLE	c.3448G>A	p.A1150T	Missense	28/49	-
13-32945177-C-A	BRCA2	c.8572C>A	p.Q2858K	Missense	20/27	-
17-7578245-G-C	TP53	c.604C>G	p.R202G	Missense	6/11	-
17-7573939-C-T	TP53	c.1088G>A	p.R363K	Missense	10/11	-
17-7574014-A-G	TP53	c.1013T>C	p.F338S	Missense	10/11	-
17-7576893-G-A	TP53	c.953C>T	p.P318L	Missense	9/11	-
17-7576900-G-T	TP53	c.946C>A	p.P316T	Missense	9/11	-
17-7576916-G-C	TP53	c.930C>G	p.N310K	Missense	9/11	-
17-7576916-G-T	TP53	c.930C>A	p.N310K	Missense	9/11	-
17-7577051-T-C	TP53	c.887A>G	p.H296R	Missense	8/11	-
17-7577087-G-A	TP53	c.851C>T	p.T284I	Missense	8/11	-
17-7577147-A-G	TP53	c.791T>C	p.L264P	Missense	8/11	-
17-7577149-A-T	TP53	c.789T>A	p.N263K	Missense	8/11	-
17-7577151-T-G	TP53	c.787A>C	p.N263H	Missense	8/11	-
17-7579353-C-G	TP53	c.334G>C	p.G112R	Missense	4/11	-
17-7579362-A-G	TP53	c.325T>C	p.F109L	Missense	4/11	-
17-7577587-T-G	TP53	c.694A>C	p.I232L	Missense	7/11	-
17-7577595-C-G	TP53	c.686G>C	p.C229S	Missense	7/11	-
17-7578422-T-C	TP53	c.508A>G	p.T170A	Missense	5/11	-
17-7578466-G-C	TP53	c.464C>G	p.T155S	Missense	5/11	-
17-7578491-C-T	TP53	c.439G>A	p.V147I	Missense	5/11	-
17-7578494-A-C	TP53	c.436T>G	p.W146G	Missense	5/11	-
17-7578511-G-T	TP53	c.419C>A	p.T140N	Missense	5/11	-
17-7579401-A-T	TP53	c.286T>A	p.S96T	Missense	4/11	-
17-7578533-T-C	TP53	c.397A>G	p.M133V	Missense	5/11	-
17-7578524-G-T	TP53	c.406C>A	p.Q136K	Missense	5/11	-
17-7578253-C-G	TP53	c.596G>C	p.G199A	Missense	6/11	-
17-7576914-T-G	TP53	c.932A>C	p.N311T	Missense	9/11	-
17-7579319-G-A	TP53	c.368C>T	p.T123I	Missense	4/11	-
17-7579359-G-T	TP53	c.328C>A	p.R110S	Missense	4/11	-
17-7579338-C-T	TP53	c.349G>A	p.G117R	Missense	4/11	-
17-7579398-C-A	TP53	c.289G>T	p.V97F	Missense	4/11	-
17-7579466-G-A	TP53	c.221C>T	p.A74V	Missense	4/11	-
17-7579489-C-T	TP53	c.198G>A	p.M66I	Missense	4/11	-
17-7579493-C-G	TP53	c.194G>C	p.R65T	Missense	4/11	-
17-7579580-G-T	TP53	c.107C>A	p.P36Q	Missense	4/11	-
17-7577024-T-A	TP53	c.914A>T	p.K305M	Missense	8/11	-
17-7579566-C-T	TP53	c.121G>A	p.D41N	Missense	4/11	-
17-7579414-C-A	TP53	c.273G>T	p.W91C	Missense	4/11	-
19-50918834-G-C	POLD1	c.2704G>C	p.E902Q	Missense	21/27	-
12-133210913-C-T	POLE	c.5863G>A	p.D1955N	Missense	43/49	-
17-7576894-G-A	TP53	c.952C>T	p.P318S	Missense	9/11	-
17-7579414-C-G	TP53	c.273G>C	p.W91C	Missense	4/11	-
12-133256108-C-T	POLE	c.553G>A	p.D185N	Missense	6/49	-
12-133245048-C-A	POLE	c.2067G>T	p.Q689H	Missense	19/49	-
12-133245048-C-G	POLE	c.2067G>C	p.Q689H	Missense	19/49	-
12-133242014-G-A	POLE	c.2342C>T	p.A781V	Missense	21/49	-
12-112888158-C-A	PTPN11	c.174C>A	p.N58K	Missense	3/16	-
17-7577072-A-C	TP53	c.866T>G	p.L289R	Missense	8/11	-
12-133225558-T-C	POLE	c.4106A>G	p.N1369S	Missense	32/49	-
13-29001982-C-T	FLT1	c.1183G>A	p.V395I	Missense	9/30	-
1-9783259-G-A	PIK3CD	c.2503G>A	p.A835T	Missense	20/24	-
4-55146616-C-T	PDGFRA	c.2290C>T	p.R764C	Missense	16/23	-
12-133263850-C-T	POLE	c.52G>A	p.E18K	Missense	1/49	-
19-50905324-G-T	POLD1	c.532G>T	p.G178W	Missense	5/27	-
19-50905495-C-T	POLD1	c.623C>T	p.P208L	Missense	6/27	-
12-133219113-G-A	POLE	c.4931C>T	p.S1644L	Missense	37/49	-
3-12626680-C-T	RAF1	c.1609G>A	p.V537I	Missense	15/17	-
17-7579397-A-G	TP53	c.290T>C	p.V97A	Missense	4/11	-
12-133250211-C-T	POLE	c.1309G>A	p.V437M	Missense	13/49	-
17-7579331-G-C	TP53	c.356C>G	p.A119G	Missense	4/11	-
17-7578193-G-C	TP53	c.656C>G	p.P219R	Missense	6/11	-
12-133219839-G-A	POLE	c.4522C>T	p.R1508C	Missense	35/49	-
12-133212497-G-A	POLE	c.5792C>T	p.S1931F	Missense	42/49	-
12-133256155-T-C	POLE	c.506A>G	p.E169G	Missense	6/49	-
19-50909575-T-G	POLD1	c.1379T>G	p.L460R	Missense	11/27	-
12-133256610-G-T	POLE	c.353C>A	p.S118Y	Missense	5/49	-
12-133249264-C-G	POLE	c.1635G>C	p.E545D	Missense	15/49	-
12-133249264-C-A	POLE	c.1635G>T	p.E545D	Missense	15/49	-
12-133244226-G-A	POLE	c.2182C>T	p.R728W	Missense	20/49	-
19-50916686-G-A	POLD1	c.2158G>A	p.V720I	Missense	18/27	-
19-50918720-G-C	POLD1	c.2590G>C	p.A864P	Missense	21/27	-
19-50920487-G-A	POLD1	c.3179G>A	p.R1060H	Missense	26/27	-
15-99251133-A-C	IGF1R	c.437A>C	p.N146T	Missense	2/21	-
7-55229232-G-T	EGFR	c.1539G>T	p.E513D	Missense	13/28	-
12-133219993-C-T	POLE	c.4444G>A	p.G1482R	Missense	34/49	-
17-41267770-G-C	BRCA1	c.107C>G	p.S36C	Missense	3/23	-
1-9784941-C-T	PIK3CD	c.2944C>T	p.R982W	Missense	23/24	-
12-133248848-C-G	POLE	c.1747G>C	p.E583Q	Missense	16/49	-
12-133245307-T-C	POLE	c.1940A>G	p.D647G	Missense	18/49	-
7-128851596-C-G	SMO	c.1921C>G	p.P641A	Missense	11/12	-
12-133248815-T-C	POLE	c.1780A>G	p.T594A	Missense	16/49	-
12-133201565-G-A	POLE	c.6673C>T	p.R2225C	Missense	48/49	-
17-7579331-G-T	TP53	c.356C>A	p.A119D	Missense	4/11	-
19-50909673-C-T	POLD1	c.1393C>T	p.R465W	Missense	12/27	-
12-133252014-G-A	POLE	c.1196C>T	p.A399V	Missense	12/49	-
12-133201393-A-G	POLE	c.6751T>C	p.F2251L	Missense	49/49	-
12-133225574-G-A	POLE	c.4090C>T	p.R1364C	Missense	32/49	-
1-9783218-G-A	PIK3CD	c.2462G>A	p.R821H	Missense	20/24	-
17-7578485-A-G	TP53	c.445T>C	p.S149P	Missense	5/11	-
17-7578417-C-A	TP53	c.513G>T	p.E171D	Missense	5/11	-
17-7579406-G-A	TP53	c.281C>T	p.S94L	Missense	4/11	-
17-7579489-C-G	TP53	c.198G>C	p.M66I	Missense	4/11	-
17-7579489-C-A	TP53	c.198G>T	p.M66I	Missense	4/11	-
17-37868256-A-G	ERBB2	c.977A>G	p.D326G	Missense	8/27	-
17-7579410-G-T	TP53	c.277C>A	p.L93M	Missense	4/11	-
12-133253989-G-A	POLE	c.761C>T	p.P254L	Missense	8/49	-
19-50920456-C-T	POLD1	c.3148C>T	p.R1050C	Missense	26/27	-
12-133226471-G-A	POLE	c.3587C>T	p.T1196M	Missense	30/49	-
17-37866371-C-A	ERBB2	c.676C>A	p.R226S	Missense	6/27	-
19-50906394-G-A	POLD1	c.1055G>A	p.R352H	Missense	9/27	-
19-50905617-G-A	POLD1	c.745G>A	p.D249N	Missense	6/27	-
12-133220482-T-C	POLE	c.4231A>G	p.I1411V	Missense	33/49	-
12-133201570-T-C	POLE	c.6668A>G	p.K2223R	Missense	48/49	-
17-7579452-C-T	TP53	c.235G>A	p.A79T	Missense	4/11	-
10-89720731-T-A	PTEN	c.882T>A	p.S294R	Missense	8/9	-
10-89720729-A-C	PTEN	c.880A>C	p.S294R	Missense	8/9	-
19-50902307-G-A	POLD1	c.199G>A	p.D67N	Missense	2/27	-
17-7577061-C-G	TP53	c.877G>C	p.G293R	Missense	8/11	-
12-133245473-C-T	POLE	c.1847G>A	p.R616H	Missense	17/49	-
17-7578473-G-C	TP53	c.457C>G	p.P153A	Missense	5/11	-
7-140476813-C-A	BRAF	c.1593G>T	p.W531C	Missense	13/18	-
12-133263850-C-G	POLE	c.52G>C	p.E18Q	Missense	1/49	-
12-133226047-G-A	POLE	c.3850C>T	p.R1284W	Missense	31/49	-
19-50919036-G-A	POLD1	c.2773G>A	p.V925M	Missense	22/27	-
17-7579501-T-G	TP53	c.186A>C	p.E62D	Missense	4/11	-
17-7579501-T-A	TP53	c.186A>T	p.E62D	Missense	4/11	-
19-50919693-C-T	POLD1	c.2861C>T	p.T954M	Missense	23/27	-
19-50920313-G-A	POLD1	c.3079G>A	p.E1027K	Missense	25/27	-
17-37882044-A-G	ERBB2	c.2810A>G	p.K937R	Missense	23/27	-
17-7577532-G-C	TP53	c.749C>G	p.P250R	Missense	7/11	-
4-1807841-G-A	FGFR3	c.1900G>A	p.A634T	Missense	14/18	-
2-29606678-C-T	ALK	c.1202G>A	p.R401Q	Missense	5/29	-
3-12650274-C-A	RAF1	c.572G>T	p.R191I	Missense	5/17	-
8-38271300-G-A	FGFR1	c.2315C>T	p.P772L	Missense	18/18	-
12-133244960-C-T	POLE	c.2155G>A	p.E719K	Missense	19/49	-
12-133248877-C-T	POLE	c.1718G>A	p.R573Q	Missense	16/49	-
X-47426127-C-T	ARAF	c.647C>T	p.P216L	Missense	7/16	-
12-133252047-C-T	POLE	c.1163G>A	p.G388D	Missense	12/49	-
19-41837031-C-T	TGFB1	c.1099G>A	p.V367M	Missense	7/7	-
12-133225959-G-A	POLE	c.3938C>T	p.T1313M	Missense	31/49	-
12-133257855-C-A	POLE	c.73G>T	p.A25S	Missense	2/49	-
17-7578547-G-C	TP53	c.383C>G	p.P128R	Missense	5/11	-
17-7579331-G-A	TP53	c.356C>T	p.A119V	Missense	4/11	-
19-50905546-G-A	POLD1	c.674G>A	p.R225H	Missense	6/27	-
19-50905086-C-A	POLD1	c.368C>A	p.P123H	Missense	4/27	-
12-133238206-C-T	POLE	c.2771G>A	p.R924H	Missense	24/49	-
19-50905990-G-A	POLD1	c.962G>A	p.G321D	Missense	8/27	-
12-133238143-G-A	POLE	c.2834C>T	p.S945F	Missense	24/49	-
19-50919734-C-T	POLD1	c.2902C>T	p.R968C	Missense	23/27	-
17-7579542-C-A	TP53	c.145G>T	p.D49Y	Missense	4/11	-
12-133215806-C-G	POLE	c.5457G>C	p.M1819I	Missense	40/49	-
12-133215806-C-T	POLE	c.5457G>A	p.M1819I	Missense	40/49	-
12-133215806-C-A	POLE	c.5457G>T	p.M1819I	Missense	40/49	-
12-133256162-T-A	POLE	c.499A>T	p.R167W	Missense	6/49	-
12-133248830-G-A	POLE	c.1765C>T	p.P589S	Missense	16/49	-
19-50902178-G-A	POLD1	c.70G>A	p.D24N	Missense	2/27	-
12-133253155-T-C	POLE	c.886A>G	p.I296V	Missense	9/49	-
12-133225598-G-C	POLE	c.4066C>G	p.H1356D	Missense	32/49	-
12-133226041-G-A	POLE	c.3856C>T	p.R1286C	Missense	31/49	-
19-50905288-C-T	POLD1	c.496C>T	p.R166W	Missense	5/27	-
17-7574000-C-G	TP53	c.1027G>C	p.E343Q	Missense	10/11	-
12-133241978-C-T	POLE	c.2378G>A	p.R793H	Missense	21/49	-
19-50902628-G-T	POLD1	c.203G>T	p.G68V	Missense	3/27	-
19-50905043-C-G	POLD1	c.325C>G	p.Q109E	Missense	4/27	-
4-55139789-G-A	PDGFRA	c.1450G>A	p.V484M	Missense	10/23	-
12-133252035-T-C	POLE	c.1175A>G	p.D392G	Missense	12/49	-
12-133253156-C-T	POLE	c.885G>A	p.M295I	Missense	9/49	-
12-133253146-T-C	POLE	c.895A>G	p.M299V	Missense	9/49	-
12-133252328-A-G	POLE	c.1099T>C	p.F367L	Missense	11/49	-
12-133252326-A-T	POLE	c.1101T>A	p.F367L	Missense	11/49	-
12-133252326-A-C	POLE	c.1101T>G	p.F367L	Missense	11/49	-
12-133250249-A-G	POLE	c.1271T>C	p.L424P	Missense	13/49	-
17-7578208-T-G	TP53	c.641A>C	p.H214P	Missense	6/11	-
7-55259469-G-T	EGFR	c.2527G>T	p.V843L	Missense	21/28	-
7-55211072-G-T	EGFR	c.315G>T	p.Q105H	Missense	3/28	-
7-55211072-G-C	EGFR	c.315G>C	p.Q105H	Missense	3/28	-
12-133256171-C-A	POLE	c.490G>T	p.V164F	Missense	6/49	-
7-55224280-C-T	EGFR	c.1061C>T	p.T354M	Missense	9/28	-
7-55259469-G-C	EGFR	c.2527G>C	p.V843L	Missense	21/28	-
17-7579360-G-T	TP53	c.327C>A	p.F109L	Missense	4/11	-
17-7579360-G-C	TP53	c.327C>G	p.F109L	Missense	4/11	-
7-55210023-G-C	EGFR	c.133G>C	p.E45Q	Missense	2/28	-
7-55220268-T-C	EGFR	c.658T>C	p.S220P	Missense	6/28	-
7-55214408-G-A	EGFR	c.534G>A	p.M178I	Missense	4/28	-
7-55218998-G-A	EGFR	c.571G>A	p.D191N	Missense	5/28	-
7-55238884-C-T	EGFR	c.1897C>T	p.L633F	Missense	16/28	-
7-55268959-G-A	EGFR	c.3025G>A	p.D1009N	Missense	25/28	-
7-55210029-C-T	EGFR	c.139C>T	p.H47Y	Missense	2/28	-
7-116339752-A-G	MET	c.614A>G	p.Y205C	Missense	2/21	-
12-133256768-C-T	POLE	c.326G>A	p.R109K	Missense	4/49	-
12-133249350-G-A	POLE	c.1549C>T	p.P517S	Missense	15/49	-
12-133248817-A-G	POLE	c.1778T>C	p.V593A	Missense	16/49	-
12-133249830-C-T	POLE	c.1393G>A	p.A465T	Missense	14/49	-
12-133235942-C-T	POLE	c.3214G>A	p.A1072T	Missense	26/49	-
12-133219243-G-A	POLE	c.4801C>T	p.P1601S	Missense	37/49	-
17-7578275-G-T	TP53	c.574C>A	p.Q192K	Missense	6/11	-
12-133250264-A-C	POLE	c.1256T>G	p.V419G	Missense	13/49	-
17-7574029-C-G	TP53	c.998G>C	p.R333P	Missense	10/11	-
4-55152054-G-A	PDGFRA	c.2486G>A	p.G829E	Missense	18/23	-
12-112888136-T-C	PTPN11	c.152T>C	p.V51A	Missense	3/16	-
17-7577103-C-G	TP53	c.835G>C	p.G279R	Missense	8/11	-
12-133249224-G-A	POLE	c.1675C>T	p.R559W	Missense	15/49	-
12-133226280-C-A	POLE	c.3778G>T	p.A1260S	Missense	30/49	-
17-7578417-C-G	TP53	c.513G>C	p.E171D	Missense	5/11	-
17-7576886-C-A	TP53	c.960G>T	p.K320N	Missense	9/11	-
12-133257231-C-A	POLE	c.247G>T	p.D83Y	Missense	3/49	-
12-133249381-C-A	POLE	c.1518G>T	p.M506I	Missense	15/49	-
17-7578230-C-T	TP53	c.619G>A	p.D207N	Missense	6/11	-
12-133257827-C-A	POLE	c.101G>T	p.R34L	Missense	2/49	-
12-133218925-G-A	POLE	c.5011C>T	p.L1671F	Missense	38/49	-
19-50918231-C-T	POLD1	c.2548C>T	p.R850C	Missense	20/27	-
12-133256789-G-A	POLE	c.305C>T	p.P102L	Missense	4/49	-
17-7579508-G-C	TP53	c.179C>G	p.P60R	Missense	4/11	-
5-67592121-T-C	PIK3R1	c.1937T>C	p.F646S	Missense	15/16	-
17-7578221-T-G	TP53	c.628A>C	p.N210H	Missense	6/11	-
17-7578220-T-G	TP53	c.629A>C	p.N210T	Missense	6/11	-
13-32944694-G-C	BRCA2	c.8487G>C	p.Q2829H	Missense	19/27	-
12-133249758-G-T	POLE	c.1465C>A	p.P489T	Missense	14/49	-
17-7579337-C-G	TP53	c.350G>C	p.G117A	Missense	4/11	-
12-133252733-T-G	POLE	c.967A>C	p.T323P	Missense	10/49	-
17-7578503-C-G	TP53	c.427G>C	p.V143L	Missense	5/11	-
12-133201301-G-T	POLE	c.6843C>A	p.N2281K	Missense	49/49	-
17-7576864-A-G	TP53	c.982T>C	p.F328L	Missense	9/11	-
2-29416299-C-G	ALK	c.4654G>C	p.G1552R	Missense	29/29	-
2-29416299-C-T	ALK	c.4654G>A	p.G1552R	Missense	29/29	-
9-90219898-G-A	DAPK1	c.92G>A	p.R31H	Missense	3/26	-
1-16458581-G-A	EPHA2	c.2303C>T	p.P768L	Missense	13/17	-
4-48114430-C-T	TXK	c.274G>A	p.D92N	Missense	4/15	-
8-38285948-G-A	FGFR1	c.364C>T	p.L122F	Missense	4/18	-
2-29541231-G-T	ALK	c.1586C>A	p.S529Y	Missense	8/29	-
8-38282044-A-T	FGFR1	c.919T>A	p.Y307N	Missense	7/18	-
2-29754929-G-A	ALK	c.1006C>T	p.P336S	Missense	4/29	-
4-1808852-G-C	FGFR3	c.2284G>C	p.D762H	Missense	18/18	-
5-176517973-G-C	FGFR4	c.471G>C	p.K157N	Missense	5/18	-
5-176517973-G-T	FGFR4	c.471G>T	p.K157N	Missense	5/18	-
2-29551261-A-G	ALK	c.1369T>C	p.F457L	Missense	6/29	-
2-29551259-G-T	ALK	c.1371C>A	p.F457L	Missense	6/29	-
2-29551259-G-C	ALK	c.1371C>G	p.F457L	Missense	6/29	-
2-29449887-A-G	ALK	c.2968T>C	p.C990R	Missense	18/29	-
2-29917765-C-A	ALK	c.903G>T	p.M301I	Missense	3/29	-
2-30142942-G-A	ALK	c.584C>T	p.A195V	Missense	1/29	-
2-29445424-C-T	ALK	c.3409G>A	p.G1137R	Missense	21/29	-
2-29445424-C-G	ALK	c.3409G>C	p.G1137R	Missense	21/29	-
2-29917765-C-G	ALK	c.903G>C	p.M301I	Missense	3/29	-
2-29917765-C-T	ALK	c.903G>A	p.M301I	Missense	3/29	-
2-29432691-G-A	ALK	c.3797C>T	p.A1266V	Missense	25/29	-
7-23775395-C-A	STK31	c.722C>A	p.P241H	Missense	7/24	-
17-7578230-C-G	TP53	c.619G>C	p.D207H	Missense	6/11	-
17-7578287-G-C	TP53	c.562C>G	p.L188V	Missense	6/11	-
12-133220107-C-A	POLE	c.4330G>T	p.V1444L	Missense	34/49	-
12-133226319-G-A	POLE	c.3739C>T	p.P1247S	Missense	30/49	-
12-133219860-C-A	POLE	c.4501G>T	p.G1501W	Missense	35/49	-
12-133234004-C-A	POLE	c.3390G>T	p.W1130C	Missense	28/49	-
3-138375084-A-G	PIK3CB	c.2975T>C	p.I992T	Missense	23/24	-
17-7579326-A-T	TP53	c.361T>A	p.S121T	Missense	4/11	-
17-7576866-T-C	TP53	c.980A>G	p.Y327C	Missense	9/11	-
17-7577148-G-C	TP53	c.790C>G	p.L264V	Missense	8/11	-
12-133209267-G-T	POLE	c.6119C>A	p.A2040E	Missense	44/49	-
12-133220518-C-G	POLE	c.4195G>C	p.E1399Q	Missense	33/49	-
12-133220518-C-T	POLE	c.4195G>A	p.E1399K	Missense	33/49	-
19-50906379-C-T	POLD1	c.1040C>T	p.P347L	Missense	9/27	-
13-32913562-A-T	BRCA2	c.5070A>T	p.K1690N	Missense	11/27	-
17-7576900-G-A	TP53	c.946C>T	p.P316S	Missense	9/11	-
17-7579487-G-A	TP53	c.200C>T	p.P67L	Missense	4/11	-
17-7577091-G-T	TP53	c.847C>A	p.R283S	Missense	8/11	-
19-50905322-G-A	POLD1	c.530G>A	p.R177H	Missense	5/27	-
12-133257260-T-C	POLE	c.218A>G	p.D73G	Missense	3/49	-
17-7579349-A-G	TP53	c.338T>C	p.F113S	Missense	4/11	-
3-178917531-G-A	PIK3CA	c.406G>A	p.V136I	Missense	3/21	-
17-7579338-C-G	TP53	c.349G>C	p.G117R	Missense	4/11	-
17-7579586-G-A	TP53	c.101C>T	p.P34L	Missense	4/11	-
17-7578482-T-G	TP53	c.448A>C	p.T150P	Missense	5/11	-
17-7578431-G-C	TP53	c.499C>G	p.Q167E	Missense	5/11	-
17-7578539-T-C	TP53	c.391A>G	p.N131D	Missense	5/11	-
17-7578435-C-A	TP53	c.495G>T	p.Q165H	Missense	5/11	-
12-133245254-G-A	POLE	c.1993C>T	p.R665W	Missense	18/49	-
12-133218852-C-T	POLE	c.5084G>A	p.G1695D	Missense	38/49	-
12-133220556-C-T	POLE	c.4157G>A	p.R1386Q	Missense	33/49	-
12-133244178-T-C	POLE	c.2230A>G	p.T744A	Missense	20/49	-
19-50920352-G-A	POLD1	c.3118G>A	p.E1040K	Missense	25/27	-
12-133214643-G-A	POLE	c.5635C>T	p.R1879C	Missense	41/49	-
12-133219144-G-A	POLE	c.4900C>T	p.R1634C	Missense	37/49	-
19-50918753-C-T	POLD1	c.2623C>T	p.R875C	Missense	21/27	-
19-50906838-G-A	POLD1	c.1226G>A	p.R409Q	Missense	10/27	-
17-7578269-G-T	TP53	c.580C>A	p.L194I	Missense	6/11	-
12-133215748-G-A	POLE	c.5515C>T	p.R1839C	Missense	40/49	-
12-133225519-C-A	POLE	c.4145G>T	p.R1382L	Missense	32/49	-
12-133210857-C-A	POLE	c.5919G>T	p.E1973D	Missense	43/49	-
12-133218360-C-A	POLE	c.5251G>T	p.A1751S	Missense	39/49	-
3-138461618-G-T	PIK3CB	c.403C>A	p.H135N	Missense	5/24	-
3-138474811-T-G	PIK3CB	c.182A>C	p.K61T	Missense	4/24	-
12-133202254-T-C	POLE	c.6634A>G	p.M2212V	Missense	47/49	-
12-133245405-G-A	POLE	c.1915C>T	p.R639C	Missense	17/49	-
12-133257726-G-A	POLE	c.202C>T	p.P68S	Missense	2/49	-
12-133226388-C-T	POLE	c.3670G>A	p.A1224T	Missense	30/49	-
19-50905742-A-G	POLD1	c.790A>G	p.N264D	Missense	7/27	-
12-133252763-C-T	POLE	c.937G>A	p.V313I	Missense	10/49	-
12-133218912-C-T	POLE	c.5024G>A	p.R1675H	Missense	38/49	-
12-133225980-G-T	POLE	c.3917C>A	p.A1306D	Missense	31/49	-
3-12650737-T-G	RAF1	c.418A>C	p.N140H	Missense	4/17	-
3-178917571-A-G	PIK3CA	c.446A>G	p.E149G	Missense	3/21	-
12-133244186-T-C	POLE	c.2222A>G	p.E741G	Missense	20/49	-
12-133257248-C-A	POLE	c.230G>T	p.R77L	Missense	3/49	-
12-133250293-C-A	POLE	c.1227G>T	p.R409S	Missense	13/49	-
12-133219410-T-C	POLE	c.4724A>G	p.Y1575C	Missense	36/49	-
17-37881078-T-C	ERBB2	c.2407T>C	p.Y803H	Missense	20/27	-
3-138374338-C-T	PIK3CB	c.3106G>A	p.E1036K	Missense	24/24	-
17-7573933-T-C	TP53	c.1094A>G	p.H365R	Missense	10/11	-
17-7573937-C-T	TP53	c.1090G>A	p.A364T	Missense	10/11	-
17-7579371-T-C	TP53	c.316A>G	p.S106G	Missense	4/11	-
12-133249251-C-A	POLE	c.1648G>T	p.G550W	Missense	15/49	-
12-133241894-C-T	POLE	c.2462G>A	p.R821H	Missense	21/49	-
12-133252770-C-G	POLE	c.930G>C	p.R310S	Missense	10/49	-
12-133252770-C-A	POLE	c.930G>T	p.R310S	Missense	10/49	-
4-55129923-A-G	PDGFRA	c.457A>G	p.T153A	Missense	4/23	-
7-128845185-C-T	SMO	c.679C>T	p.H227Y	Missense	3/12	-
19-50918759-G-A	POLD1	c.2629G>A	p.D877N	Missense	21/27	-
19-50910261-C-T	POLD1	c.1516C>T	p.R506C	Missense	13/27	-
12-133220025-C-T	POLE	c.4412G>A	p.R1471H	Missense	34/49	-
17-7578497-G-T	TP53	c.433C>A	p.L145M	Missense	5/11	-
12-133225613-C-T	POLE	c.4051G>A	p.V1351I	Missense	32/49	-
12-133202830-A-T	POLE	c.6404T>A	p.V2135D	Missense	46/49	-
3-138426123-C-T	PIK3CB	c.1408G>A	p.E470K	Missense	11/24	-
12-133254238-C-T	POLE	c.646G>A	p.D216N	Missense	7/49	-
12-133256790-G-A	POLE	c.304C>T	p.P102S	Missense	4/49	-
12-133253148-T-C	POLE	c.893A>G	p.Y298C	Missense	9/49	-
17-37872138-C-T	ERBB2	c.1459C>T	p.R487W	Missense	12/27	-
4-55144623-G-C	PDGFRA	c.2097G>C	p.E699D	Missense	15/23	-
4-55141083-C-A	PDGFRA	c.1729C>A	p.P577T	Missense	12/23	-
17-7577514-G-C	TP53	c.767C>G	p.T256R	Missense	7/11	-
4-55138564-C-T	PDGFRA	c.1241C>T	p.P414L	Missense	9/23	-
4-55156709-G-A	PDGFRA	c.3110G>A	p.R1037K	Missense	22/23	-
4-55133619-C-T	PDGFRA	c.923C>T	p.S308F	Missense	6/23	-
17-7579340-G-C	TP53	c.347C>G	p.S116C	Missense	4/11	-
17-7578229-T-G	TP53	c.620A>C	p.D207A	Missense	6/11	-
12-133256793-T-C	POLE	c.301A>G	p.K101E	Missense	4/49	-
12-133214705-C-T	POLE	c.5573G>A	p.R1858H	Missense	41/49	-
12-133226069-C-G	POLE	c.3828G>C	p.K1276N	Missense	31/49	-
19-50905605-G-A	POLD1	c.733G>A	p.E245K	Missense	6/27	-
12-133226069-C-A	POLE	c.3828G>T	p.K1276N	Missense	31/49	-
19-50919758-G-A	POLD1	c.2926G>A	p.E976K	Missense	23/27	-
19-50916738-C-A	POLD1	c.2210C>A	p.S737Y	Missense	18/27	-
12-133249842-A-T	POLE	c.1381T>A	p.S461T	Missense	14/49	-
7-140434567-G-A	BRAF	c.2131C>T	p.L711F	Missense	18/18	-
7-140494157-G-A	BRAF	c.1091C>T	p.S364L	Missense	8/18	-
17-7577139-G-C	TP53	c.799C>G	p.R267G	Missense	8/11	-
12-133219143-C-T	POLE	c.4901G>A	p.R1634H	Missense	37/49	-
1-9784908-G-A	PIK3CD	c.2911G>A	p.G971R	Missense	23/24	-
17-7577590-T-G	TP53	c.691A>C	p.T231P	Missense	7/11	-
19-50910411-G-A	POLD1	c.1666G>A	p.V556I	Missense	13/27	-
12-133215747-C-T	POLE	c.5516G>A	p.R1839H	Missense	40/49	-
17-7576923-A-G	TP53	c.923T>C	p.L308P	Missense	9/11	-
17-37879861-A-G	ERBB2	c.2156A>G	p.E719G	Missense	18/27	-
19-50910306-C-T	POLD1	c.1561C>T	p.R521W	Missense	13/27	-
19-50905485-G-A	POLD1	c.613G>A	p.G205S	Missense	6/27	-
17-7577608-C-A	TP53	c.673G>T	p.V225F	Missense	7/11	-
19-50909439-G-A	POLD1	c.1243G>A	p.V415I	Missense	11/27	-
17-7574026-C-T	TP53	c.1001G>A	p.G334E	Missense	10/11	-
17-7577154-C-A	TP53	c.784G>T	p.G262C	Missense	8/11	-
19-50910366-G-A	POLD1	c.1621G>A	p.V541M	Missense	13/27	-
12-133214718-C-T	POLE	c.5560G>A	p.A1854T	Missense	41/49	-
12-133237692-G-A	POLE	c.2923C>T	p.R975C	Missense	25/49	-
17-7578521-G-T	TP53	c.409C>A	p.L137M	Missense	5/11	-
17-7579512-C-A	TP53	c.175G>T	p.G59C	Missense	4/11	-
17-7577054-G-C	TP53	c.884C>G	p.P295R	Missense	8/11	-
19-50919938-C-T	POLD1	c.3025C>T	p.R1009C	Missense	24/27	-
17-7577608-C-G	TP53	c.673G>C	p.V225L	Missense	7/11	-
17-7577056-C-G	TP53	c.882G>C	p.E294D	Missense	8/11	-
19-50905772-G-T	POLD1	c.820G>T	p.A274S	Missense	7/27	-
12-133202800-C-T	POLE	c.6434G>A	p.R2145Q	Missense	46/49	-
12-133209346-C-T	POLE	c.6040G>A	p.G2014R	Missense	44/49	-
17-7573970-C-G	TP53	c.1057G>C	p.A353P	Missense	10/11	-
19-50918184-G-T	POLD1	c.2501G>T	p.R834M	Missense	20/27	-
19-50909516-G-C	POLD1	c.1320G>C	p.Q440H	Missense	11/27	-
12-133244162-C-T	POLE	c.2246G>A	p.R749Q	Missense	20/49	-
19-50906412-G-T	POLD1	c.1073G>T	p.R358L	Missense	9/27	-
19-50906823-C-T	POLD1	c.1211C>T	p.P404L	Missense	10/27	-
12-133209024-C-G	POLE	c.6207G>C	p.K2069N	Missense	45/49	-
12-133237736-T-C	POLE	c.2879A>G	p.N960S	Missense	25/49	-
17-7578217-G-C	TP53	c.632C>G	p.T211S	Missense	6/11	-
3-138433362-G-A	PIK3CB	c.1250C>T	p.T417M	Missense	9/24	-
12-133234501-G-A	POLE	c.3331C>T	p.R1111W	Missense	27/49	-
7-140500184-C-T	BRAF	c.958G>A	p.A320T	Missense	7/18	-
17-7579470-C-A	TP53	c.217G>T	p.V73L	Missense	4/11	-
12-133219519-C-G	POLE	c.4615G>C	p.E1539Q	Missense	36/49	-
19-50919939-G-A	POLD1	c.3026G>A	p.R1009H	Missense	24/27	-
12-133238234-C-G	POLE	c.2743G>C	p.E915Q	Missense	24/49	-
12-133218264-C-T	POLE	c.5347G>A	p.D1783N	Missense	39/49	-
19-50920457-G-A	POLD1	c.3149G>A	p.R1050H	Missense	26/27	-
12-133248806-C-T	POLE	c.1789G>A	p.E597K	Missense	16/49	-
19-50909730-G-A	POLD1	c.1450G>A	p.E484K	Missense	12/27	-
12-133202842-C-A	POLE	c.6392G>T	p.R2131L	Missense	46/49	-
19-50919728-C-T	POLD1	c.2896C>T	p.L966F	Missense	23/27	-
12-133256554-C-G	POLE	c.409G>C	p.E137Q	Missense	5/49	-
X-47430395-G-A	ARAF	c.1670G>A	p.R557Q	Missense	15/16	-
2-30143128-C-T	ALK	c.398G>A	p.R133H	Missense	1/29	-
19-50902666-C-T	POLD1	c.241C>T	p.R81W	Missense	3/27	-
12-133220437-C-A	POLE	c.4276G>T	p.V1426L	Missense	33/49	-
12-133233988-G-A	POLE	c.3406C>T	p.R1136W	Missense	28/49	-
3-138461575-C-T	PIK3CB	c.446G>A	p.R149Q	Missense	5/24	-
17-7578371-C-G	TP53	c.559G>C	p.G187R	Missense	5/11	-
17-7578374-C-A	TP53	c.556G>T	p.D186Y	Missense	5/11	-
19-50905512-G-A	POLD1	c.640G>A	p.V214M	Missense	6/27	-
12-133244114-C-T	POLE	c.2294G>A	p.R765H	Missense	20/49	-
19-50917131-G-C	POLD1	c.2383G>C	p.E795Q	Missense	19/27	-
3-12647737-G-A	RAF1	c.643C>T	p.R215C	Missense	6/17	-
12-133219213-T-C	POLE	c.4831A>G	p.I1611V	Missense	37/49	-
12-133209306-C-A	POLE	c.6080G>T	p.R2027M	Missense	44/49	-
19-50918709-C-T	POLD1	c.2579C>T	p.A860V	Missense	21/27	-
17-7578392-C-G	TP53	c.538G>C	p.E180Q	Missense	5/11	-
12-133252717-T-C	POLE	c.983A>G	p.Y328C	Missense	10/49	-
12-133210876-G-A	POLE	c.5900C>T	p.A1967V	Missense	43/49	-
17-37873579-G-A	ERBB2	c.1744G>A	p.D582N	Missense	15/27	-
12-133226321-G-A	POLE	c.3737C>T	p.T1246M	Missense	30/49	-
12-133235972-C-T	POLE	c.3184G>A	p.E1062K	Missense	26/49	-
12-133219537-C-T	POLE	c.4597G>A	p.E1533K	Missense	36/49	-
12-133219156-G-A	POLE	c.4888C>T	p.R1630W	Missense	37/49	-
12-133235900-C-A	POLE	c.3256G>T	p.G1086C	Missense	26/49	-
12-133254211-C-T	POLE	c.673G>A	p.D225N	Missense	7/49	-
12-133220041-C-G	POLE	c.4396G>C	p.E1466Q	Missense	34/49	-
17-7577150-T-C	TP53	c.788A>G	p.N263S	Missense	8/11	-
12-133226463-C-T	POLE	c.3595G>A	p.E1199K	Missense	30/49	-
12-133236009-C-A	POLE	c.3147G>T	p.Q1049H	Missense	26/49	-
12-133250172-C-T	POLE	c.1348G>A	p.E450K	Missense	13/49	-
10-123263436-G-A	FGFR2	c.1307C>T	p.S436F	Missense	10/18	-
19-50905378-G-A	POLD1	c.586G>A	p.E196K	Missense	5/27	-
17-7578451-A-C	TP53	c.479T>G	p.M160R	Missense	5/11	-
12-133220464-C-T	POLE	c.4249G>A	p.E1417K	Missense	33/49	-
17-7579530-A-C	TP53	c.157T>G	p.W53G	Missense	4/11	-
12-133249810-C-A	POLE	c.1413G>T	p.M471I	Missense	14/49	-
17-37879682-C-T	ERBB2	c.2057C>T	p.T686M	Missense	17/27	-
19-50905082-G-A	POLD1	c.364G>A	p.V122M	Missense	4/27	-
19-50910288-G-A	POLD1	c.1543G>A	p.D515N	Missense	13/27	-
12-133219552-C-T	POLE	c.4582G>A	p.A1528T	Missense	36/49	-
12-133219495-G-A	POLE	c.4639C>T	p.P1547S	Missense	36/49	-
12-133209378-T-C	POLE	c.6008A>G	p.Y2003C	Missense	44/49	-
12-133245014-C-G	POLE	c.2101G>C	p.E701Q	Missense	19/49	-
17-7579409-A-T	TP53	c.278T>A	p.L93Q	Missense	4/11	-
19-50912832-G-A	POLD1	c.2063G>A	p.G688E	Missense	17/27	-
12-133209325-C-A	POLE	c.6061G>T	p.G2021W	Missense	44/49	-
12-133220503-C-T	POLE	c.4210G>A	p.E1404K	Missense	33/49	-
3-138375001-C-G	PIK3CB	c.3058G>C	p.D1020H	Missense	23/24	-
17-7576860-G-C	TP53	c.986C>G	p.T329S	Missense	9/11	-
12-133226384-G-A	POLE	c.3674C>T	p.A1225V	Missense	30/49	-
17-7579509-G-A	TP53	c.178C>T	p.P60S	Missense	4/11	-
12-133256768-C-G	POLE	c.326G>C	p.R109T	Missense	4/49	-
17-7577144-A-T	TP53	c.794T>A	p.L265Q	Missense	8/11	-
12-133210874-C-T	POLE	c.5902G>A	p.E1968K	Missense	43/49	-
12-133220041-C-T	POLE	c.4396G>A	p.E1466K	Missense	34/49	-
17-37882093-G-A	ERBB2	c.2859G>A	p.M953I	Missense	23/27	-
17-7577540-G-C	TP53	c.741C>G	p.N247K	Missense	7/11	-
17-7577125-C-A	TP53	c.813G>T	p.E271D	Missense	8/11	-
17-7574007-C-G	TP53	c.1020G>C	p.M340I	Missense	10/11	-
17-7574007-C-T	TP53	c.1020G>A	p.M340I	Missense	10/11	-
17-7574007-C-A	TP53	c.1020G>T	p.M340I	Missense	10/11	-
12-133214625-C-T	POLE	c.5653G>A	p.A1885T	Missense	41/49	-
17-7578233-A-T	TP53	c.616T>A	p.L206M	Missense	6/11	-
19-50905623-G-C	POLD1	c.751G>C	p.E251Q	Missense	6/27	-
7-140534491-G-A	BRAF	c.422C>T	p.P141L	Missense	3/18	-
19-50910391-G-A	POLD1	c.1646G>A	p.R549H	Missense	13/27	-
19-50910318-C-T	POLD1	c.1573C>T	p.R525W	Missense	13/27	-
19-50905503-C-T	POLD1	c.631C>T	p.R211C	Missense	6/27	-
19-50919959-C-T	POLD1	c.3046C>T	p.R1016C	Missense	24/27	-
19-50905504-G-A	POLD1	c.632G>A	p.R211H	Missense	6/27	-
19-50909527-G-A	POLD1	c.1331G>A	p.R444Q	Missense	11/27	-
19-50918228-C-T	POLD1	c.2545C>T	p.R849C	Missense	20/27	-
19-50909464-G-A	POLD1	c.1268G>A	p.R423H	Missense	11/27	-
19-50909674-G-A	POLD1	c.1394G>A	p.R465Q	Missense	12/27	-
19-50912912-G-A	POLD1	c.2143G>A	p.E715K	Missense	17/27	-
19-50912404-A-G	POLD1	c.1918A>G	p.T640A	Missense	16/27	-
19-50918816-G-A	POLD1	c.2686G>A	p.G896S	Missense	21/27	-
19-50905981-A-C	POLD1	c.953A>C	p.E318A	Missense	8/27	-
12-133225974-C-T	POLE	c.3923G>A	p.R1308Q	Missense	31/49	-
17-41256276-C-G	BRCA1	c.304G>C	p.A102P	Missense	6/23	-
12-133249812-T-C	POLE	c.1411A>G	p.M471V	Missense	14/49	-
19-50918984-G-A	POLD1	c.2721G>A	p.M907I	Missense	22/27	-
17-7578511-G-C	TP53	c.419C>G	p.T140S	Missense	5/11	-
17-7578512-T-A	TP53	c.418A>T	p.T140S	Missense	5/11	-
12-133254274-C-T	POLE	c.610G>A	p.E204K	Missense	7/49	-
19-50906327-G-C	POLD1	c.988G>C	p.E330Q	Missense	9/27	-
3-138417861-T-C	PIK3CB	c.1658A>G	p.N553S	Missense	13/24	-
12-133254169-G-A	POLE	c.715C>T	p.H239Y	Missense	7/49	-
19-50920346-C-G	POLD1	c.3112C>G	p.Q1038E	Missense	25/27	-
17-7579590-A-T	TP53	c.97T>A	p.S33T	Missense	4/11	-
12-133249248-C-T	POLE	c.1651G>A	p.V551I	Missense	15/49	-
12-133233736-C-T	POLE	c.3568G>A	p.E1190K	Missense	29/49	-
12-133209071-A-C	POLE	c.6160T>G	p.Y2054D	Missense	45/49	-
12-133245404-C-T	POLE	c.1916G>A	p.R639H	Missense	17/49	-
17-7579476-G-T	TP53	c.211C>A	p.P71T	Missense	4/11	-
17-37881105-G-A	ERBB2	c.2434G>A	p.E812K	Missense	20/27	-
12-133240657-G-A	POLE	c.2639C>T	p.T880M	Missense	23/49	-
12-133218901-G-A	POLE	c.5035C>T	p.R1679C	Missense	38/49	-
17-7578375-G-C	TP53	c.555C>G	p.S185R	Missense	5/11	-
17-7578377-T-G	TP53	c.553A>C	p.S185R	Missense	5/11	-
17-7578499-T-C	TP53	c.431A>G	p.Q144R	Missense	5/11	-
17-7577148-G-T	TP53	c.790C>A	p.L264I	Missense	8/11	-
17-7577502-G-C	TP53	c.779C>G	p.S260C	Missense	7/11	-
17-7577582-G-T	TP53	c.699C>A	p.H233Q	Missense	7/11	-
17-7578200-C-G	TP53	c.649G>C	p.V217L	Missense	6/11	-
17-7578485-A-T	TP53	c.445T>A	p.S149T	Missense	5/11	-
19-50919951-T-C	POLD1	c.3038T>C	p.I1013T	Missense	24/27	-
17-7578506-G-T	TP53	c.424C>A	p.P142T	Missense	5/11	-
17-7577150-T-A	TP53	c.788A>T	p.N263I	Missense	8/11	-
17-7578492-C-A	TP53	c.438G>T	p.W146C	Missense	5/11	-
17-7578492-C-G	TP53	c.438G>C	p.W146C	Missense	5/11	-
17-7578548-G-C	TP53	c.382C>G	p.P128A	Missense	5/11	-
19-50918997-C-T	POLD1	c.2734C>T	p.P912S	Missense	22/27	-
17-7578247-A-G	TP53	c.602T>C	p.L201S	Missense	6/11	-
17-7577596-A-T	TP53	c.685T>A	p.C229S	Missense	7/11	-
17-7577027-G-T	TP53	c.911C>A	p.T304N	Missense	8/11	-
17-7576913-G-T	TP53	c.933C>A	p.N311K	Missense	9/11	-
17-7577045-T-G	TP53	c.893A>C	p.E298A	Missense	8/11	-
17-7577057-T-A	TP53	c.881A>T	p.E294V	Missense	8/11	-
17-7577070-G-T	TP53	c.868C>A	p.R290S	Missense	8/11	-
17-7577037-G-C	TP53	c.901C>G	p.P301A	Missense	8/11	-
17-7577037-G-T	TP53	c.901C>A	p.P301T	Missense	8/11	-
17-7579490-A-C	TP53	c.197T>G	p.M66R	Missense	4/11	-
17-7578218-T-A	TP53	c.631A>T	p.T211S	Missense	6/11	-
17-7578437-G-C	TP53	c.493C>G	p.Q165E	Missense	5/11	-
17-7578214-A-T	TP53	c.635T>A	p.F212Y	Missense	6/11	-
17-7578422-T-G	TP53	c.508A>C	p.T170P	Missense	5/11	-
17-7577060-C-A	TP53	c.878G>T	p.G293V	Missense	8/11	-
17-7578230-C-A	TP53	c.619G>T	p.D207Y	Missense	6/11	-
17-7578278-G-T	TP53	c.571C>A	p.P191T	Missense	6/11	-
17-7578481-G-T	TP53	c.449C>A	p.T150K	Missense	5/11	-
17-7579323-C-G	TP53	c.364G>C	p.V122L	Missense	4/11	-
17-7577043-G-C	TP53	c.895C>G	p.L299V	Missense	8/11	-
17-7579323-C-A	TP53	c.364G>T	p.V122L	Missense	4/11	-
17-7579556-A-G	TP53	c.131T>C	p.M44T	Missense	4/11	-
17-7578250-T-G	TP53	c.599A>C	p.N200T	Missense	6/11	-
17-7579316-C-T	TP53	c.371G>A	p.C124Y	Missense	4/11	-
17-7579334-G-C	TP53	c.353C>G	p.T118R	Missense	4/11	-
17-7579578-A-T	TP53	c.109T>A	p.S37T	Missense	4/11	-
17-7579511-C-T	TP53	c.176G>A	p.G59D	Missense	4/11	-
17-7579514-G-T	TP53	c.173C>A	p.P58Q	Missense	4/11	-
17-7579340-G-A	TP53	c.347C>T	p.S116F	Missense	4/11	-
17-7577149-A-C	TP53	c.789T>G	p.N263K	Missense	8/11	-
17-7578238-T-A	TP53	c.611A>T	p.E204V	Missense	6/11	-
17-7578397-T-A	TP53	c.533A>T	p.H178L	Missense	5/11	-
17-7578376-C-A	TP53	c.554G>T	p.S185I	Missense	5/11	-
17-7578373-T-A	TP53	c.557A>T	p.D186V	Missense	5/11	-
17-7578434-A-T	TP53	c.496T>A	p.S166T	Missense	5/11	-
17-7577078-T-A	TP53	c.860A>T	p.E287V	Missense	8/11	-
17-7578428-G-C	TP53	c.502C>G	p.H168D	Missense	5/11	-
17-7578500-G-T	TP53	c.430C>A	p.Q144K	Missense	5/11	-
17-7577067-T-G	TP53	c.871A>C	p.K291Q	Missense	8/11	-
17-7579469-A-T	TP53	c.218T>A	p.V73E	Missense	4/11	-
17-7578193-G-T	TP53	c.656C>A	p.P219H	Missense	6/11	-
17-7577578-T-G	TP53	c.703A>C	p.N235H	Missense	7/11	-
12-133252086-C-T	POLE	c.1124G>A	p.R375Q	Missense	12/49	-
12-133244992-T-C	POLE	c.2123A>G	p.H708R	Missense	19/49	-
12-133226444-G-A	POLE	c.3614C>T	p.P1205L	Missense	30/49	-
19-50918130-C-G	POLD1	c.2447C>G	p.S816C	Missense	20/27	-
12-133219168-G-A	POLE	c.4876C>T	p.R1626C	Missense	37/49	-
17-7579463-G-T	TP53	c.224C>A	p.P75H	Missense	4/11	-
17-7573970-C-A	TP53	c.1057G>T	p.A353S	Missense	10/11	-
17-7579868-A-C	TP53	c.45T>G	p.S15R	Missense	2/11	-
17-7579868-A-T	TP53	c.45T>A	p.S15R	Missense	2/11	-
17-7576909-T-G	TP53	c.937A>C	p.S313R	Missense	9/11	-
17-7576908-C-A	TP53	c.938G>T	p.S313I	Missense	9/11	-
17-7579404-A-T	TP53	c.283T>A	p.S95T	Missense	4/11	-
17-7577134-G-T	TP53	c.804C>A	p.N268K	Missense	8/11	-
17-7579425-C-T	TP53	c.262G>A	p.A88T	Missense	4/11	-
17-41258515-C-T	BRCA1	c.170G>A	p.G57E	Missense	4/23	-
17-7577057-T-G	TP53	c.881A>C	p.E294A	Missense	8/11	-
17-7577602-A-C	TP53	c.679T>G	p.S227A	Missense	7/11	-
17-7573997-G-T	TP53	c.1030C>A	p.L344M	Missense	10/11	-
17-7579574-T-A	TP53	c.113A>T	p.Q38L	Missense	4/11	-
17-7573978-A-T	TP53	c.1049T>A	p.L350H	Missense	10/11	-
12-133249757-G-T	POLE	c.1466C>A	p.P489H	Missense	14/49	-
17-7579332-C-A	TP53	c.355G>T	p.A119S	Missense	4/11	-
12-133245434-G-A	POLE	c.1886C>T	p.A629V	Missense	17/49	-
12-133256594-C-A	POLE	c.369G>T	p.K123N	Missense	5/49	-
5-67593261-T-A	PIK3R1	c.2007T>A	p.H669Q	Missense	16/16	-
17-7578472-G-C	TP53	c.458C>G	p.P153R	Missense	5/11	-
12-133250276-C-T	POLE	c.1244G>A	p.S415N	Missense	13/49	-
17-7577042-A-T	TP53	c.896T>A	p.L299Q	Missense	8/11	-
17-7578401-G-C	TP53	c.529C>G	p.P177A	Missense	5/11	-
12-133236035-G-A	POLE	c.3121C>T	p.R1041W	Missense	26/49	-
19-50912441-G-T	POLD1	c.1955G>T	p.R652L	Missense	16/27	-
X-47428244-G-A	ARAF	c.1204G>A	p.D402N	Missense	11/16	-
12-133256774-G-A	POLE	c.320C>T	p.A107V	Missense	4/49	-
12-133219540-C-T	POLE	c.4594G>A	p.A1532T	Missense	36/49	-
17-7579319-G-T	TP53	c.368C>A	p.T123N	Missense	4/11	-