PMID: 35087742

Investigation of PALB2 Mutation and Correlation With Immunotherapy Biomarker in Chinese Non-Small Cell Lung Cancer Patients.

Frontiers in oncology

Zhang, Jiexia J, Tang, Shuangfeng S, Zhang, Chunning C, Li, Mingyao M, Zheng, Yating Y, Hu, Xue X, Huang, Mengli M, Cheng, Xiangyang X

2021

3243 variants were identified in this publication

Variant ID	Gene	cDNA	Protein	Consequence	Exon	Intron
7-81332000-C-T	HGF	c.2084G>A	p.R695H	Missense	18/18	-
17-7579311-C-T	TP53	c.375+1G>A	-	IntronicSNV	-	4/10
7-55242470-T-C	EGFR	c.2240T>C	p.L747S	Missense	19/28	-
2-234669619-C-A	UGT1A1	c.686C>A	p.P229Q	Missense	1/5	-
2-234669144-G-A	UGT1A1	c.211G>A	p.G71R	Missense	1/5	-
15-66729181-A-G	MAP2K1	c.389A>G	p.Y130C	Missense	3/11	-
4-1806119-G-C	FGFR3	c.1138G>C	p.G380R	Missense	9/18	-
6-18139228-C-T	TPMT	c.460G>A	p.A154T	Missense	6/9	-
17-7578205-C-A	TP53	c.644G>T	p.S215I	Missense	6/11	-
17-7579312-C-T	TP53	c.375G>A	p.T125=	Synonymous	4/11	-
17-7579312-C-A	TP53	c.375G>T	p.T125=	Synonymous	4/11	-
17-7579312-C-G	TP53	c.375G>C	p.T125=	Synonymous	4/11	-
5-112174665-T-C	APC	c.3374T>C	p.V1125A	Missense	16/16	-
5-112174669-C-G	APC	c.3378C>G	p.S1126R	Missense	16/16	-
17-7578271-T-G	TP53	c.578A>C	p.H193P	Missense	6/11	-
17-7578235-T-A	TP53	c.614A>T	p.Y205F	Missense	6/11	-
17-7577556-C-A	TP53	c.725G>T	p.C242F	Missense	7/11	-
6-32188943-G-A	NOTCH4	c.611C>T	p.P204L	Missense	4/30	-
17-7578478-G-C	TP53	c.452C>G	p.P151R	Missense	5/11	-
6-18130918-T-C	TPMT	c.719A>G	p.Y240C	Missense	9/9	-
1-97915624-A-G	DPYD	c.1896T>C	p.F632=	Synonymous	14/23	-
2-215632255-C-A	BARD1	c.1519G>T	p.V507L	Missense	6/11	-
2-215632255-C-T	BARD1	c.1519G>A	p.V507M	Missense	6/11	-
7-55242469-TT-CC	EGFR	c.2239_2240delTTinsCC	p.L747P	Missense	19/28	-
16-2121610-G-A	TSC2	c.1939G>A	p.D647N	Missense	18/42	-
16-2130189-G-A	TSC2	c.3421G>A	p.A1141T	Missense	30/42	-
17-7577099-C-G	TP53	c.839G>C	p.R280T	Missense	8/11	-
9-135797253-G-C	TSC1	c.616C>G	p.H206D	Missense	7/23	-
17-7577560-A-C	TP53	c.721T>G	p.S241A	Missense	7/11	-
9-21971199-C-G	CDKN2A	c.159G>C	p.M53I	Missense	2/3	-
17-7578239-C-A	TP53	c.610G>T	p.E204*	Nonsense	6/11	-
17-7577090-C-G	TP53	c.848G>C	p.R283P	Missense	8/11	-
22-42526694-G-A	CYP2D6	c.100C>T	p.P34S	Missense	1/9	-
3-41266113-C-G	CTNNB1	c.110C>G	p.S37C	Missense	3/15	-
13-32954180-C-T	BRCA2	c.9154C>T	p.R3052W	Missense	24/27	-
1-97981395-T-C	DPYD	c.1627A>G	p.I543V	Missense	13/23	-
7-55242465-AGGAATTAAGAGAAGC-A	EGFR	c.2235_2249del15	p.E746_A750del	InFrameDeletion	19/28	-
7-55242466-GGAATTAAGAGAAGCA-G	EGFR	c.2236_2250del15	p.E746_A750del	InFrameDeletion	19/28	-
19-48664717-G-A	LIG1	c.155C>T	p.P52L	Missense	4/28	-
13-32893361-A-G	BRCA2	c.215A>G	p.N72S	Missense	3/27	-
17-41245262-T-A	BRCA1	c.2286A>T	p.R762S	Missense	10/23	-
17-41246512-G-A	BRCA1	c.1036C>T	p.P346S	Missense	10/23	-
19-1220640-C-T	STK11	c.658C>T	p.Q220*	Nonsense	5/10	-
19-1220382-C-T	STK11	c.475C>T	p.Q159*	Nonsense	4/10	-
7-140481411-C-A	BRAF	c.1397G>T	p.G466V	Missense	11/18	-
7-55241678-A-C	EGFR	c.2126A>C	p.E709A	Missense	18/28	-
7-55242469-TTAAGAGAAG-C	EGFR	c.2239_2248delinsC	p.L747_A750delinsP	MultiAAMissense	19/28	-
7-55242469-TTAAGAGAAGCAA-C	EGFR	c.2239_2251delinsC	p.L747_T751delinsP	MultiAAMissense	19/28	-
17-7578427-T-C	TP53	c.503A>G	p.H168R	Missense	5/11	-
3-41266101-C-A	CTNNB1	c.98C>A	p.S33Y	Missense	3/15	-
3-41266101-C-T	CTNNB1	c.98C>T	p.S33F	Missense	3/15	-
13-32931957-G-T	BRCA2	c.7696G>T	p.D2566Y	Missense	16/27	-
7-55242467-AATTAAGAGAAGCAAC-A	EGFR	c.2240_2254del15	p.L747_T751del	InFrameDeletion	19/28	-
7-55242470-TTAAGAGAAGCAACATCTC-T	EGFR	c.2240_2257del18	p.L747_P753delinsS	MultiAAMissense	19/28	-
7-55241679-AAAC-A	EGFR	c.2127_2129delAAC	p.E709_T710delinsD	MultiAAMissense	18/28	-
4-110908981-T-G	EGF	c.2573T>G	p.L858W	Missense	17/24	-
17-7577536-T-C	TP53	c.745A>G	p.R249G	Missense	7/11	-
21-36164601-G-A	RUNX1	c.1274C>T	p.P425L	Missense	9/9	-
17-7578235-T-C	TP53	c.614A>G	p.Y205C	Missense	6/11	-
17-7578211-C-A	TP53	c.638G>T	p.R213L	Missense	6/11	-
3-178917478-G-A	PIK3CA	c.353G>A	p.G118D	Missense	3/21	-
9-21974751-C-A	CDKN2A	c.76G>T	p.E26*	Nonsense	1/3	-
2-29446307-G-A	ALK	c.3260C>T	p.T1087I	Missense	20/29	-
17-7578479-G-A	TP53	c.451C>T	p.P151S	Missense	5/11	-
17-7577545-T-C	TP53	c.736A>G	p.M246V	Missense	7/11	-
17-7577118-C-A	TP53	c.820G>T	p.V274F	Missense	8/11	-
7-6045597-T-G	PMS2	c.89A>C	p.Q30P	Missense	2/15	-
7-6042169-C-T	PMS2	c.452G>A	p.R151H	Missense	5/15	-
17-7579414-C-T	TP53	c.273G>A	p.W91*	Nonsense	4/11	-
17-7577547-C-A	TP53	c.734G>T	p.G245V	Missense	7/11	-
17-7578478-G-T	TP53	c.452C>A	p.P151H	Missense	5/11	-
17-7577100-T-C	TP53	c.838A>G	p.R280G	Missense	8/11	-
17-7577106-G-A	TP53	c.832C>T	p.P278S	Missense	8/11	-
17-59876546-G-A	BRIP1	c.1255C>T	p.R419W	Missense	9/20	-
3-178952072-A-G	PIK3CA	c.3127A>G	p.M1043V	Missense	21/21	-
7-140481417-C-A	BRAF	c.1391G>T	p.G464V	Missense	11/18	-
3-178952074-G-C	PIK3CA	c.3129G>C	p.M1043I	Missense	21/21	-
17-7578211-C-T	TP53	c.638G>A	p.R213Q	Missense	6/11	-
17-7577108-C-A	TP53	c.830G>T	p.C277F	Missense	8/11	-
7-55241617-G-T	EGFR	c.2065G>T	p.V689L	Missense	18/28	-
17-7577548-C-A	TP53	c.733G>T	p.G245C	Missense	7/11	-
11-108098555-A-G	ATM	c.125A>G	p.H42R	Missense	3/63	-
16-23641340-G-A	PALB2	c.2135C>T	p.A712V	Missense	5/13	-
13-48955431-G-A	RB1	c.1547G>A	p.W516*	Nonsense	17/27	-
17-7577538-C-G	TP53	c.743G>C	p.R248P	Missense	7/11	-
X-76907781-TTCC-T	ATRX	c.4377_4379delGGA	p.E1464del	InFrameDeletion	15/35	-
17-7577114-C-A	TP53	c.824G>T	p.C275F	Missense	8/11	-
17-7578469-C-A	TP53	c.461G>T	p.G154V	Missense	5/11	-
17-7577127-C-A	TP53	c.811G>T	p.E271*	Nonsense	8/11	-
17-7574026-C-A	TP53	c.1001G>T	p.G334V	Missense	10/11	-
17-7578280-G-A	TP53	c.569C>T	p.P190L	Missense	6/11	-
17-7574012-C-A	TP53	c.1015G>T	p.E339*	Nonsense	10/11	-
5-112175951-G-GA	APC	c.4666_4666dupA	p.T1556Nfs*3	Frameshift	16/16	-
3-53531239-C-T	CACNA1D	c.128C>T	p.P43L	Missense	2/48	-
10-123258034-A-C	FGFR2	c.1647T>G	p.N549K	Missense	12/18	-
10-123258034-A-T	FGFR2	c.1647T>A	p.N549K	Missense	12/18	-
10-123260370-C-T	FGFR2	c.1531G>A	p.A511T	Missense	11/18	-
10-123274833-G-A	FGFR2	c.1085C>T	p.A362V	Missense	9/18	-
12-49425022-C-T	KMT2D	c.13466G>A	p.G4489E	Missense	40/55	-
7-81359056-G-T	HGF	c.905C>A	p.T302K	Missense	8/18	-
4-1801001-G-A	FGFR3	c.130G>A	p.G44S	Missense	3/18	-
4-1795748-G-C	FGFR3	c.87G>C	p.Q29H	Missense	2/18	-
12-49446160-C-T	KMT2D	c.1306G>A	p.E436K	Missense	11/55	-
7-81381528-C-T	HGF	c.533G>A	p.R178Q	Missense	5/18	-
10-8100631-G-A	GATA3	c.605G>A	p.R202H	Missense	3/6	-
12-49426345-G-A	KMT2D	c.12143C>T	p.P4048L	Missense	40/55	-
8-38274887-T-C	FGFR1	c.1600A>G	p.M534V	Missense	12/18	-
4-1806192-A-G	FGFR3	c.1211A>G	p.K404R	Missense	9/18	-
4-1807385-G-C	FGFR3	c.1634G>C	p.C545S	Missense	12/18	-
4-1807167-G-A	FGFR3	c.1498G>A	p.A500T	Missense	11/18	-
4-1807488-G-C	FGFR3	c.1657G>C	p.V553L	Missense	13/18	-
4-1807545-C-T	FGFR3	c.1714C>T	p.P572S	Missense	13/18	-
7-116436149-C-T	MET	c.4144C>T	p.R1382*	Nonsense	21/21	-
12-49441822-G-A	KMT2D	c.4162C>T	p.R1388W	Missense	15/55	-
12-49418454-C-T	KMT2D	c.15959G>A	p.R5320H	Missense	51/55	-
7-116339633-G-C	MET	c.495G>C	p.Q165H	Missense	2/21	-
12-49443502-C-T	KMT2D	c.3869G>A	p.R1290Q	Missense	12/55	-
7-116339635-T-C	MET	c.497T>C	p.I166T	Missense	2/21	-
7-116340251-C-A	MET	c.1113C>A	p.N371K	Missense	2/21	-
12-49431759-C-T	KMT2D	c.9380G>A	p.R3127H	Missense	35/55	-
7-116339755-T-C	MET	c.617T>C	p.F206S	Missense	2/21	-
22-30032795-G-A	NF2	c.170G>A	p.R57Q	Missense	2/16	-
7-116340330-T-C	MET	c.1192T>C	p.F398L	Missense	2/21	-
6-18139802-A-T	TPMT	c.419+94T>A	-	IntronicSNV	-	5/8
18-48591919-G-A	SMAD4	c.1082G>A	p.R361H	Missense	9/12	-
17-7578404-A-T	TP53	c.526T>A	p.C176S	Missense	5/11	-
17-7577536-T-A	TP53	c.745A>T	p.R249W	Missense	7/11	-
17-7577574-T-C	TP53	c.707A>G	p.Y236C	Missense	7/11	-
17-7578266-T-A	TP53	c.583A>T	p.I195F	Missense	6/11	-
17-7578271-T-A	TP53	c.578A>T	p.H193L	Missense	6/11	-
17-7577551-C-A	TP53	c.730G>T	p.G244C	Missense	7/11	-
17-37880261-G-T	ERBB2	c.2305G>T	p.D769Y	Missense	19/27	-
17-7578407-G-C	TP53	c.523C>G	p.R175G	Missense	5/11	-
17-7577569-A-T	TP53	c.712T>A	p.C238S	Missense	7/11	-
17-7579415-C-T	TP53	c.272G>A	p.W91*	Nonsense	4/11	-
9-98212185-C-T	PTCH1	c.3487G>A	p.G1163S	Missense	21/24	-
17-7578388-C-G	TP53	c.542G>C	p.R181P	Missense	5/11	-
18-48591918-C-T	SMAD4	c.1081C>T	p.R361C	Missense	9/12	-
17-7578529-A-C	TP53	c.401T>G	p.F134C	Missense	5/11	-
17-7578443-A-T	TP53	c.487T>A	p.Y163N	Missense	5/11	-
3-178936083-A-G	PIK3CA	c.1625A>G	p.E542G	Missense	10/21	-
17-62006798-T-G	CD79B	c.587A>C	p.Y196S	Missense	5/6	-
3-178936091-G-C	PIK3CA	c.1633G>C	p.E545Q	Missense	10/21	-
17-7577093-C-G	TP53	c.845G>C	p.R282P	Missense	8/11	-
17-7577129-A-C	TP53	c.809T>G	p.F270C	Missense	8/11	-
10-43607597-C-T	RET	c.1573C>T	p.R525W	Missense	8/20	-
10-96609771-G-A	CYP2C19	c.1247G>A	p.G416D	Missense	8/9	-
9-21971186-G-A	CDKN2A	c.172C>T	p.R58*	Nonsense	2/3	-
5-67592076-G-A	PIK3R1	c.1892G>A	p.R631Q	Missense	15/16	-
7-55242467-AATTAAGAGAAGCAACATC-T	EGFR	c.2237_2255delinsT	p.E746_S752delinsV	MultiAAMissense	19/28	-
1-97915746-G-A	DPYD	c.1774C>T	p.R592W	Missense	14/23	-
16-23641218-G-A	PALB2	c.2257C>T	p.R753*	Nonsense	5/13	-
17-7578392-C-T	TP53	c.538G>A	p.E180K	Missense	5/11	-
17-7577096-T-A	TP53	c.842A>T	p.D281V	Missense	8/11	-
10-96612495-C-T	CYP2C19	c.1297C>T	p.R433W	Missense	9/9	-
10-96535210-G-A	CYP2C19	c.395G>A	p.R132Q	Missense	3/9	-
17-7577058-C-A	TP53	c.880G>T	p.E294*	Nonsense	8/11	-
2-198267483-C-T	SF3B1	c.1874G>A	p.R625H	Missense	14/25	-
11-119149245-T-C	CBL	c.1253T>C	p.F418S	Missense	9/16	-
15-66782095-A-C	MAP2K1	c.1062A>C	p.Q354H	Missense	10/11	-
7-142460750-G-C	PRSS1	c.623G>C	p.G208A	Missense	5/5	-
17-7578177-C-T	TP53	c.672G>A	p.E224=	Synonymous	6/11	-
5-35871238-C-T	IL7R	c.460C>T	p.H154Y	Missense	4/8	-
21-44524486-A-G	U2AF1	c.71T>C	p.I24T	Missense	2/8	-
3-47098379-C-T	SETD2	c.6895G>A	p.G2299R	Missense	15/21	-
19-11097111-A-T	SMARCA4	c.602A>T	p.Q201L	Missense	4/35	-
7-151932949-C-A	KMT2C	c.2722G>T	p.G908C	Missense	16/59	-
17-40474420-C-A	STAT3	c.1981G>T	p.D661Y	Missense	21/24	-
2-178098953-C-A	NFE2L2	c.92G>T	p.G31V	Missense	2/5	-
2-178098954-C-T	NFE2L2	c.91G>A	p.G31R	Missense	2/5	-
2-178098954-C-G	NFE2L2	c.91G>C	p.G31R	Missense	2/5	-
16-23649272-C-T	PALB2	c.110G>A	p.R37H	Missense	3/13	-
17-7578542-G-C	TP53	c.388C>G	p.L130V	Missense	5/11	-
16-2134572-C-G	TSC2	c.4349C>G	p.P1450R	Missense	34/42	-
2-25467448-C-G	DNMT3A	c.1628G>C	p.G543A	Missense	14/23	-
11-108205805-C-G	ATM	c.8120C>G	p.S2707C	Missense	55/63	-
17-41244100-G-A	BRCA1	c.3448C>T	p.P1150S	Missense	10/23	-
3-52621445-T-A	PBRM1	c.2972A>T	p.E991V	Missense	20/30	-
7-151882672-C-A	KMT2C	c.5053G>T	p.A1685S	Missense	34/59	-
17-7578553-T-C	TP53	c.377A>G	p.Y126C	Missense	5/11	-
16-23641307-CAT-C	PALB2	c.2167_2168delAT	p.M723Vfs*21	Frameshift	5/13	-
11-534285-C-A	HRAS	c.38G>T	p.G13V	Missense	2/6	-
5-131931451-TA-T	RAD50	c.2165delA	p.K722Rfs*14	Frameshift	13/25	-
17-7577018-C-T	TP53	c.919+1G>A	-	IntronicSNV	-	8/10
17-7577018-C-A	TP53	c.919+1G>T	-	IntronicSNV	-	8/10
1-27105700-C-T	ARID1A	c.5311C>T	p.P1771S	Missense	20/20	-
17-7576852-C-A	TP53	c.993+1G>T	-	IntronicSNV	-	9/10
1-27100171-C-T	ARID1A	c.3967C>T	p.R1323C	Missense	16/20	-
1-27097694-C-T	ARID1A	c.3283C>T	p.Q1095*	Nonsense	12/20	-
17-7577568-C-A	TP53	c.713G>T	p.C238F	Missense	7/11	-
17-29685568-A-G	NF1	c.8041A>G	p.I2681V	Missense	55/58	-
17-29562705-C-G	NF1	c.3785C>G	p.S1262C	Missense	28/58	-
9-98209597-G-A	PTCH1	c.3941C>T	p.P1314L	Missense	23/24	-
20-62178623-C-T	SRMS	c.194G>A	p.R65Q	Missense	1/8	-
17-7573948-C-G	TP53	c.1079G>C	p.G360A	Missense	10/11	-
3-178928079-G-C	PIK3CA	c.1357G>C	p.E453Q	Missense	8/21	-
17-7576897-G-A	TP53	c.949C>T	p.Q317*	Nonsense	9/11	-
11-108235879-C-T	ATM	c.8921C>T	p.P2974L	Missense	62/63	-
11-108213973-G-A	ATM	c.8293G>A	p.G2765S	Missense	57/63	-
3-178916836-C-G	PIK3CA	c.223C>G	p.Q75E	Missense	2/21	-
17-7577082-C-A	TP53	c.856G>T	p.E286*	Nonsense	8/11	-
2-29443696-A-C	ALK	c.3521T>G	p.F1174C	Missense	23/29	-
17-37863347-C-G	ERBB2	c.178C>G	p.L60V	Missense	2/27	-
2-48027824-G-A	MSH6	c.2702G>A	p.R901H	Missense	4/10	-
7-151970859-C-T	KMT2C	c.943G>A	p.G315S	Missense	7/59	-
17-7578179-C-A	TP53	c.670G>T	p.E224*	Nonsense	6/11	-
7-55211079-A-G	EGFR	c.322A>G	p.R108G	Missense	3/28	-
9-21971111-G-A	CDKN2A	c.247C>T	p.H83Y	Missense	2/3	-
16-67645924-C-A	CTCF	c.852C>A	p.H284Q	Missense	4/12	-
9-21971017-G-A	CDKN2A	c.341C>T	p.P114L	Missense	2/3	-
1-27057727-C-T	ARID1A	c.1435C>T	p.Q479*	Nonsense	3/20	-
X-70595092-C-T	TAF1	c.488C>T	p.P143L	Missense	4/38	-
17-7576855-G-A	TP53	c.991C>T	p.Q331*	Nonsense	9/11	-
1-11189845-G-T	MTOR	c.5664C>A	p.F1888L	Missense	40/58	-
13-73346338-C-T	DIS3	c.1462G>A	p.D488N	Missense	10/21	-
17-7578479-G-C	TP53	c.451C>G	p.P151A	Missense	5/11	-
17-7577112-C-G	TP53	c.826G>C	p.A276P	Missense	8/11	-
17-7577559-G-C	TP53	c.722C>G	p.S241C	Missense	7/11	-
10-96535204-C-T	CYP2C19	c.389C>T	p.T130M	Missense	3/9	-
3-178916930-G-T	PIK3CA	c.317G>T	p.G106V	Missense	2/21	-
17-7578467-T-G	TP53	c.463A>C	p.T155P	Missense	5/11	-
2-178098944-C-T	NFE2L2	c.101G>A	p.R34Q	Missense	2/5	-
X-123197716-C-T	STAG2	c.1840C>T	p.R614*	Nonsense	20/35	-
17-7578395-G-T	TP53	c.535C>A	p.H179N	Missense	5/11	-
17-7578191-A-C	TP53	c.658T>G	p.Y220D	Missense	6/11	-
17-7577138-C-G	TP53	c.800G>C	p.R267P	Missense	8/11	-
17-7577581-A-T	TP53	c.700T>A	p.Y234N	Missense	7/11	-
17-7579494-T-A	TP53	c.193A>T	p.R65*	Nonsense	4/11	-
13-25021245-A-G	PARP4	c.3194T>C	p.V1065A	Missense	26/34	-
19-10475348-C-T	TYK2	c.1309G>A	p.E437K	Missense	9/25	-
5-35876536-C-A	IL7R	c.1328C>A	p.S443*	Nonsense	8/8	-
17-7578263-G-C	TP53	c.586C>G	p.R196G	Missense	6/11	-
15-89876861-C-T	POLG	c.125G>A	p.R42Q	Missense	2/23	-
8-139268993-C-A	FAM135B	c.307G>T	p.A103S	Missense	5/20	-
2-29416705-C-A	ALK	c.4248G>T	p.K1416N	Missense	29/29	-
9-98218641-C-T	PTCH1	c.3223G>A	p.G1075R	Missense	19/24	-
2-29416380-T-C	ALK	c.4573A>G	p.K1525E	Missense	29/29	-
4-187525601-G-A	FAT1	c.10478C>T	p.P3493L	Missense	18/27	-
16-89851273-G-A	FANCA	c.1459C>T	p.R487W	Missense	15/43	-
5-56177848-TCAA-T	MAP3K1	c.2845_2847delACA	p.T949del	InFrameDeletion	14/20	-
7-42005963-G-A	GLI3	c.2708C>T	p.S903L	Missense	15/15	-
7-55238900-C-T	EGFR	c.1913C>T	p.T638M	Missense	16/28	-
9-21971108-C-G	CDKN2A	c.250G>C	p.D84H	Missense	2/3	-
15-50784955-C-A	USP8	c.2292C>A	p.N764K	Missense	15/20	-
7-55259442-G-T	EGFR	c.2500G>T	p.V834L	Missense	21/28	-
9-21970913-C-A	CDKN2A	c.445G>T	p.E149*	Nonsense	2/3	-
5-44310536-T-C	FGF10	c.422A>G	p.Y141C	Missense	2/3	-
17-29654655-A-G	NF1	c.5407A>G	p.I1803V	Missense	38/58	-
17-29657493-G-A	NF1	c.5789G>A	p.C1930Y	Missense	39/58	-
5-80109532-A-G	MSH3	c.2785A>G	p.I929V	Missense	20/24	-
4-187549515-G-A	FAT1	c.4603C>T	p.R1535*	Nonsense	9/27	-
17-29585518-A-G	NF1	c.4330A>G	p.K1444E	Missense	32/58	-
17-29667553-G-T	NF1	c.6952G>T	p.V2318L	Missense	47/58	-
17-7576888-T-A	TP53	c.958A>T	p.K320*	Nonsense	9/11	-
18-48604655-G-A	SMAD4	c.1477G>A	p.D493N	Missense	12/12	-
12-115112026-C-T	TBX3	c.1654G>A	p.G552R	Missense	6/7	-
17-29552252-A-G	NF1	c.1985A>G	p.K662R	Missense	17/58	-
3-178941879-A-G	PIK3CA	c.2198A>G	p.K733R	Missense	15/21	-
17-41201197-T-G	BRCA1	c.5347A>C	p.M1783L	Missense	21/23	-
17-41199678-C-A	BRCA1	c.5449G>T	p.E1817*	Nonsense	22/23	-
19-10602836-C-T	KEAP1	c.742G>A	p.A248T	Missense	3/6	-
16-23649269-G-A	PALB2	c.113C>T	p.A38V	Missense	3/13	-
7-140453124-C-A	BRAF	c.1811G>T	p.W604L	Missense	15/18	-
16-23646208-G-T	PALB2	c.1659C>A	p.H553Q	Missense	4/13	-
12-49427912-C-T	KMT2D	c.10678G>A	p.D3560N	Missense	39/55	-
1-158585163-G-T	SPTA1	c.6631C>A	p.R2211S	Missense	48/52	-
17-37880997-G-GTGT	ERBB2	c.2326_2327insTGT	p.G776delinsVC	MultiAAMissense	20/27	-
16-89877149-C-T	FANCA	c.488G>A	p.R163H	Missense	5/43	-
18-51795960-A-G	POLI	c.44A>G	p.D15G	Missense	1/10	-
8-90971041-C-T	NBN	c.1036G>A	p.V346M	Missense	9/16	-
13-32907183-A-G	BRCA2	c.1568A>G	p.H523R	Missense	10/27	-
8-90995017-A-G	NBN	c.104T>C	p.I35T	Missense	2/16	-
11-108099994-A-C	ATM	c.275A>C	p.K92T	Missense	4/63	-
11-108138009-G-A	ATM	c.2578G>A	p.D860N	Missense	17/63	-
11-108192078-C-T	ATM	c.6503C>T	p.S2168L	Missense	45/63	-
5-131977907-C-T	RAD50	c.3790C>T	p.L1264F	Missense	25/25	-
13-32913027-G-A	BRCA2	c.4535G>A	p.R1512H	Missense	11/27	-
13-32912568-C-T	BRCA2	c.4076C>T	p.T1359I	Missense	11/27	-
13-32912868-A-G	BRCA2	c.4376A>G	p.N1459S	Missense	11/27	-
13-32913091-A-C	BRCA2	c.4599A>C	p.K1533N	Missense	11/27	-
16-23646375-C-A	PALB2	c.1492G>T	p.D498Y	Missense	4/13	-
13-32972800-C-T	BRCA2	c.10150C>T	p.R3384*	Nonsense	27/27	-
16-23614962-A-G	PALB2	c.3379T>C	p.C1127R	Missense	13/13	-
16-23632708-T-C	PALB2	c.3088A>G	p.T1030A	Missense	10/13	-
16-23640966-C-T	PALB2	c.2509G>A	p.E837K	Missense	5/13	-
16-23641186-C-G	PALB2	c.2289G>C	p.L763F	Missense	5/13	-
16-23641247-T-C	PALB2	c.2228A>G	p.Y743C	Missense	5/13	-
16-23641346-G-A	PALB2	c.2129C>T	p.T710M	Missense	5/13	-
16-23641520-C-T	PALB2	c.1955G>A	p.S652N	Missense	5/13	-
16-23646594-C-T	PALB2	c.1273G>A	p.V425M	Missense	4/13	-
16-23646654-G-C	PALB2	c.1213C>G	p.P405A	Missense	4/13	-
16-23647638-A-G	PALB2	c.229T>C	p.C77R	Missense	4/13	-
7-55242481-ACATCTCCGAAAGCCAACAAGGAAATC-TCT	EGFR	c.2251_2277delinsTCT	p.T751_I759delinsS	MultiAAMissense	19/28	-
17-41245201-T-C	BRCA1	c.2347A>G	p.I783V	Missense	10/23	-
5-79950715-G-C	MSH3	c.169G>C	p.A57P	Missense	1/24	-
19-10610382-T-C	KEAP1	c.328A>G	p.M110V	Missense	2/6	-
16-23647149-G-T	PALB2	c.718C>A	p.P240T	Missense	4/13	-
9-139395158-G-A	NOTCH1	c.5780C>T	p.T1927M	Missense	31/34	-
17-41246724-C-T	BRCA1	c.824G>A	p.G275D	Missense	10/23	-
17-41246737-C-T	BRCA1	c.811G>A	p.V271M	Missense	10/23	-
22-29090043-C-T	CHEK2	c.1438G>A	p.A480T	Missense	13/15	-
22-29091846-G-A	CHEK2	c.1111C>T	p.H371Y	Missense	11/15	-
22-29107934-C-T	CHEK2	c.755G>A	p.S252N	Missense	6/15	-
6-106553729-C-A	PRDM1	c.1694C>A	p.P565Q	Missense	5/7	-
16-23619203-G-A	PALB2	c.3332C>T	p.P1111L	Missense	12/13	-
16-23641146-C-T	PALB2	c.2329G>A	p.D777N	Missense	5/13	-
17-29559777-C-T	NF1	c.3374C>T	p.A1125V	Missense	26/58	-
16-23646813-C-G	PALB2	c.1054G>C	p.E352Q	Missense	4/13	-
21-36252876-C-G	RUNX1	c.486G>C	p.R162S	Missense	5/9	-
15-91328217-G-A	BLM	c.2729G>A	p.R910K	Missense	14/22	-
1-11272529-G-A	MTOR	c.3401C>T	p.A1134V	Missense	23/58	-
22-29095882-G-A	CHEK2	c.952C>T	p.R318C	Missense	9/15	-
11-108224493-G-T	ATM	c.8672G>T	p.G2891V	Missense	60/63	-
13-32906411-T-C	BRCA2	c.796T>C	p.F266L	Missense	10/27	-
16-89858883-C-T	FANCA	c.1079G>A	p.R360H	Missense	12/43	-
3-181430151-G-A	SOX2	c.3G>A	p.M1?	Missense	1/1	-
3-37053562-C-T	MLH1	c.649C>T	p.R217C	Missense	8/19	-
2-47637371-A-G	MSH2	c.505A>G	p.I169V	Missense	3/16	-
2-47693946-A-G	MSH2	c.1660A>G	p.S554G	Missense	10/16	-
7-6026708-C-T	PMS2	c.1688G>A	p.R563Q	Missense	11/15	-
10-89692836-A-T	PTEN	c.320A>T	p.D107V	Missense	5/9	-
16-14026103-G-A	ERCC4	c.1063G>A	p.E355K	Missense	6/11	-
16-72992630-G-T	ZFHX3	c.1415C>A	p.A472E	Missense	2/10	-
17-29556953-G-A	NF1	c.2951G>A	p.G984E	Missense	22/58	-
2-141458125-G-A	LRP1B	c.6493C>T	p.R2165W	Missense	41/91	-
2-212251659-C-G	ERBB4	c.3400G>C	p.V1134L	Missense	27/28	-
13-32972378-C-T	BRCA2	c.9728C>T	p.P3243L	Missense	27/27	-
2-47705625-G-A	MSH2	c.2425G>A	p.E809K	Missense	14/16	-
9-21974714-GGCAGCGCCCCCGCCTCCA-G	CDKN2A	c.95_112del18	p.L32_L37del	InFrameDeletion	1/3	-
9-80537095-G-T	GNAQ	c.303C>A	p.Y101*	Nonsense	2/7	-
18-48591975-A-T	SMAD4	c.1138A>T	p.R380W	Missense	9/12	-
2-212495294-T-A	ERBB4	c.1972A>T	p.I658F	Missense	17/28	-
1-11298542-T-C	MTOR	c.1919A>G	p.H640R	Missense	12/58	-
12-57864754-G-A	GLI1	c.2231G>A	p.G744E	Missense	12/12	-
9-98242839-C-A	PTCH1	c.778G>T	p.D260Y	Missense	6/24	-
5-112176926-G-T	APC	c.5635G>T	p.A1879S	Missense	16/16	-
7-116415163-G-A	MET	c.3257G>A	p.R1086K	Missense	15/21	-
17-46804397-C-G	HOXB13	c.610G>C	p.G204R	Missense	2/2	-
16-10031816-G-A	GRIN2A	c.1007C>T	p.P336L	Missense	3/13	-
13-48937093-G-T	RB1	c.861G>T	p.E287D	Missense	8/27	-
5-112173830-G-T	APC	c.2539G>T	p.E847*	Nonsense	16/16	-
17-38512270-G-T	RARA	c.1181G>T	p.R394L	Missense	9/9	-
17-7579715-AG-A	TP53	c.80delC	p.P27Lfs*17	Frameshift	3/11	-
19-10610405-G-A	KEAP1	c.305C>T	p.S102L	Missense	2/6	-
17-29553477-A-AC	NF1	c.2033dupC	p.I679Dfs*21	Frameshift	18/58	-
10-89720798-GTACT-G	PTEN	c.955_958delACTT	p.T319*	Frameshift	8/9	-
17-7577500-TG-T	TP53	c.780delC	p.S261Vfs*84	Frameshift	7/11	-
17-7579854-GA-G	TP53	c.58delT	p.S20Qfs*24	Frameshift	2/11	-
17-7579470-CG-C	TP53	c.216delC	p.V73Wfs*50	Frameshift	4/11	-
19-50917023-G-A	POLD1	c.2275G>A	p.V759I	Missense	19/27	-
17-7578504-AG-A	TP53	c.425delC	p.P142Lfs*28	Frameshift	5/11	-
17-7577035-TG-T	TP53	c.902delC	p.P301Qfs*44	Frameshift	8/11	-
3-30691871-G-GA	TGFBR2	c.383_383dupA	p.P129Afs*3	Frameshift	3/7	-
17-7577594-ACAGT-A	TP53	c.683_686delACTG	p.D228Vfs*18	Frameshift	7/11	-
7-116412044-G-T	MET	c.3028+1G>T	-	IntronicSNV	-	14/20
7-152055688-TTC-T	KMT2C	c.232_233delGA	p.E78Nfs*17	Frameshift	2/59	-
22-24176351-CG-C	SMARCB1	c.1144delG	p.A382Pfs*101	Frameshift	9/9	-
17-29486112-G-T	NF1	c.288+1G>T	-	IntronicSNV	-	3/57
5-112154963-C-T	APC	c.1234C>T	p.Q412*	Nonsense	10/16	-
15-99465657-G-T	IGF1R	c.2482G>T	p.A828S	Missense	11/21	-
9-21971185-C-T	CDKN2A	c.173G>A	p.R58Q	Missense	2/3	-
17-41243952-G-A	BRCA1	c.3596C>T	p.A1199V	Missense	10/23	-
9-21974783-C-T	CDKN2A	c.44G>A	p.W15*	Nonsense	1/3	-
16-23646627-G-A	PALB2	c.1240C>T	p.R414*	Nonsense	4/13	-
10-89711892-T-G	PTEN	c.510T>G	p.S170R	Missense	6/9	-
7-140624440-C-T	BRAF	c.64G>A	p.D22N	Missense	1/18	-
X-53241007-C-A	KDM5C	c.1204G>T	p.D402Y	Missense	9/26	-
7-142459834-C-T	PRSS1	c.410C>T	p.T137M	Missense	3/5	-
9-21971108-C-A	CDKN2A	c.250G>T	p.D84Y	Missense	2/3	-
16-23646750-C-T	PALB2	c.1117G>A	p.E373K	Missense	4/13	-
X-76944369-T-C	ATRX	c.536A>G	p.N179S	Missense	7/35	-
16-2104300-G-A	TSC2	c.340G>A	p.E114K	Missense	5/42	-
6-43748521-C-T	VEGFA	c.1015C>T	p.R339W	Missense	6/8	-
2-209113210-T-C	IDH1	c.297A>G	p.I99M	Missense	4/10	-
22-29091741-G-A	CHEK2	c.1216C>T	p.R406C	Missense	11/15	-
16-3786796-C-G	CREBBP	c.4415G>C	p.W1472S	Missense	27/31	-
16-3789597-C-T	CREBBP	c.4262G>A	p.C1421Y	Missense	25/31	-
2-178098973-C-G	NFE2L2	c.72G>C	p.W24C	Missense	2/5	-
3-12641304-G-C	RAF1	c.994C>G	p.P332A	Missense	10/17	-
10-89690831-A-T	PTEN	c.238A>T	p.K80*	Nonsense	4/9	-
17-7578446-T-A	TP53	c.484A>T	p.I162F	Missense	5/11	-
2-215593551-G-A	BARD1	c.2183C>T	p.S728F	Missense	11/11	-
2-215610562-C-T	BARD1	c.1694G>A	p.R565H	Missense	8/11	-
2-215645825-A-G	BARD1	c.773T>C	p.I258T	Missense	4/11	-
13-48936983-C-T	RB1	c.751C>T	p.R251*	Nonsense	8/27	-
13-49030386-C-A	RB1	c.1861C>A	p.R621S	Missense	19/27	-
5-149502704-C-T	PDGFRB	c.2084G>A	p.R695H	Missense	15/23	-
17-59763272-G-C	BRIP1	c.2830C>G	p.Q944E	Missense	19/20	-
1-11188164-G-C	MTOR	c.5930C>G	p.T1977R	Missense	43/58	-
5-156675967-C-T	ITK	c.1741C>T	p.R581W	Missense	16/17	-
3-10183734-C-G	VHL	c.203C>G	p.S68W	Missense	1/3	-
13-48919300-T-A	RB1	c.465T>A	p.Y155*	Nonsense	4/27	-
9-135778098-T-C	TSC1	c.2285A>G	p.N762S	Missense	18/23	-
7-42005678-G-C	GLI3	c.2993C>G	p.P998R	Missense	15/15	-
2-47710068-C-T	MSH2	c.2785C>T	p.R929*	Nonsense	16/16	-
9-98209585-G-A	PTCH1	c.3953C>T	p.P1318L	Missense	23/24	-
9-135772614-G-C	TSC1	c.2932C>G	p.L978V	Missense	22/23	-
17-7577135-T-A	TP53	c.803A>T	p.N268I	Missense	8/11	-
15-91312426-C-T	BLM	c.2371C>T	p.R791C	Missense	11/22	-
19-1220400-G-T	STK11	c.493G>T	p.E165*	Nonsense	4/10	-
16-89818581-G-A	FANCA	c.3031C>T	p.R1011C	Missense	31/43	-
X-39932995-G-A	BCOR	c.1604C>T	p.A535V	Missense	4/15	-
7-128850922-G-C	SMO	c.1769G>C	p.S590T	Missense	10/12	-
3-52643672-C-A	PBRM1	c.2224G>T	p.E742*	Nonsense	17/30	-
16-23646257-G-A	PALB2	c.1610C>T	p.S537L	Missense	4/13	-
16-23641115-G-A	PALB2	c.2360C>T	p.T787I	Missense	5/13	-
9-21974724-C-G	CDKN2A	c.103G>C	p.G35R	Missense	1/3	-
7-116412043-G-T	MET	c.3028G>T	p.D1010Y	Missense	14/21	-
4-55131118-C-T	PDGFRA	c.661C>T	p.L221F	Missense	5/23	-
5-112174944-C-T	APC	c.3653C>T	p.T1218M	Missense	16/16	-
16-23641367-A-C	PALB2	c.2108T>G	p.L703*	Nonsense	5/13	-
17-59870989-C-T	BRIP1	c.1442G>A	p.G481D	Missense	10/20	-
17-59763248-T-C	BRIP1	c.2854A>G	p.I952V	Missense	19/20	-
7-151962134-G-T	KMT2C	c.1173C>A	p.C391*	Nonsense	8/59	-
9-21971036-C-G	CDKN2A	c.322G>C	p.D108H	Missense	2/3	-
5-112179623-G-T	APC	c.8332G>T	p.A2778S	Missense	16/16	-
2-48026185-G-A	MSH6	c.1063G>A	p.G355S	Missense	4/10	-
2-29445397-G-T	ALK	c.3436C>A	p.Q1146K	Missense	21/29	-
13-32912864-C-T	BRCA2	c.4372C>T	p.H1458Y	Missense	11/27	-
2-215609831-C-A	BARD1	c.1863G>T	p.M621I	Missense	9/11	-
9-135781467-G-A	TSC1	c.1498C>T	p.R500*	Nonsense	15/23	-
12-133249752-C-T	POLE	c.1471G>A	p.E491K	Missense	14/49	-
18-48586278-A-G	SMAD4	c.947A>G	p.N316S	Missense	8/12	-
12-133225520-G-A	POLE	c.4144C>T	p.R1382C	Missense	32/49	-
5-131911578-A-G	RAD50	c.323A>G	p.K108R	Missense	3/25	-
2-47703697-G-A	MSH2	c.2197G>A	p.A733T	Missense	13/16	-
13-32893238-G-A	BRCA2	c.92G>A	p.W31*	Nonsense	3/27	-
17-7579549-G-T	TP53	c.138C>A	p.S46=	Synonymous	4/11	-
7-151962168-C-A	KMT2C	c.1139G>T	p.R380L	Missense	8/59	-
9-139397639-A-C	NOTCH1	c.5162T>G	p.V1721G	Missense	27/34	-
22-22221645-G-A	MAPK1	c.86C>T	p.S29L	Missense	1/9	-
1-65304196-G-T	JAK1	c.2919C>A	p.N973K	Missense	21/25	-
16-23649269-G-C	PALB2	c.113C>G	p.A38G	Missense	3/13	-
2-215645300-T-C	BARD1	c.1298A>G	p.H433R	Missense	4/11	-
9-133759489-CAAG-C	ABL1	c.1826_1828delAGA	p.K609del	InFrameDeletion	11/11	-
17-29588851-C-G	NF1	c.4700C>G	p.S1567*	Nonsense	35/58	-
19-1207105-G-T	STK11	c.193G>T	p.E65*	Nonsense	1/10	-
17-66511629-T-A	PRKAR1A	c.89T>A	p.L30Q	Missense	2/11	-
10-43620336-G-A	RET	c.2945G>A	p.R982H	Missense	18/20	-
2-178098975-A-G	NFE2L2	c.70T>C	p.W24R	Missense	2/5	-
2-178098816-C-A	NFE2L2	c.229G>T	p.D77Y	Missense	2/5	-
2-178098962-A-G	NFE2L2	c.83T>C	p.I28T	Missense	2/5	-
2-178098950-A-C	NFE2L2	c.95T>G	p.V32G	Missense	2/5	-
15-88423601-C-A	NTRK3	c.2234G>T	p.R745L	Missense	19/20	-
5-149504392-G-A	PDGFRB	c.1810C>T	p.R604C	Missense	13/23	-
4-55604628-C-T	KIT	c.2836C>T	p.R946*	Nonsense	21/21	-
15-99250824-A-G	IGF1R	c.128A>G	p.Y43C	Missense	2/21	-
17-41228533-T-A	BRCA1	c.4456A>T	p.S1486C	Missense	13/23	-
2-47601060-G-A	EPCAM	c.298G>A	p.D100N	Missense	3/9	-
14-95570399-T-C	DICER1	c.3334A>G	p.N1112D	Missense	21/27	-
16-9916248-G-A	GRIN2A	c.2041C>T	p.R681*	Nonsense	10/13	-
3-52442614-T-A	BAP1	c.131A>T	p.Y44F	Missense	4/17	-
9-21974695-CG-C	CDKN2A	c.132delC	p.Y44*	Frameshift	1/3	-
9-21974776-GGCCA-G	CDKN2A	c.47_50delTGGC	p.L16Pfs*9	Frameshift	1/3	-
17-7579419-AG-A	TP53	c.267delC	p.S90Pfs*33	Frameshift	4/11	-
1-27105930-TG-T	ARID1A	c.5548delG	p.D1850Tfs*33	Frameshift	20/20	-
12-121432117-G-GC	HNF1A	c.872dupC	p.G292Rfs*25	Frameshift	4/10	-
16-23646807-AT-A	PALB2	c.1059delA	p.K353Nfs*3	Frameshift	4/13	-
16-23646825-GTTCTT-G	PALB2	c.1037_1041delAAGAA	p.K346Tfs*13	Frameshift	4/13	-
16-23614914-G-GT	PALB2	c.3426_3426dupA	p.L1143Tfs*14	Frameshift	13/13	-
12-133201522-G-A	POLE	c.6716C>T	p.A2239V	Missense	48/49	-
17-17118625-CA-C	FLCN	c.1305delT	p.F435Lfs*33	Frameshift	12/14	-
17-38510606-C-T	RARA	c.860C>T	p.S287L	Missense	7/9	-
16-89857848-C-T	FANCA	c.1322G>A	p.G441D	Missense	14/43	-
16-3808917-G-A	CREBBP	c.3307C>T	p.R1103*	Nonsense	17/31	-
16-23635403-G-GT	PALB2	c.2760_2760dupA	p.Q921Tfs*7	Frameshift	8/13	-
12-57606328-C-A	LRP1	c.13625C>A	p.P4542H	Missense	89/89	-
1-27101282-G-A	ARID1A	c.4564G>A	p.A1522T	Missense	18/20	-
10-89717777-G-T	PTEN	c.801+1G>T	-	IntronicSNV	-	7/8
5-1293662-G-A	TERT	c.1339C>T	p.R447C	Missense	2/16	-
1-19062330-G-A	PAX7	c.1360G>A	p.V454M	Missense	8/9	-
10-104375107-G-A	SUFU	c.1105G>A	p.V369I	Missense	9/12	-
16-89805325-G-A	FANCA	c.4225C>T	p.R1409W	Missense	42/43	-
12-133209313-C-T	POLE	c.6073G>A	p.V2025M	Missense	44/49	-
11-128786614-G-C	KCNJ5	c.1248G>C	p.R416S	Missense	3/3	-
1-120458081-G-T	NOTCH2	c.7264C>A	p.P2422T	Missense	34/34	-
1-155870205-G-A	RIT1	c.634C>T	p.R212W	Missense	6/6	-
12-4479663-G-A	FGF23	c.602C>T	p.P201L	Missense	3/3	-
19-30314667-G-T	CCNE1	c.1216G>T	p.G406W	Missense	12/12	-
16-2138544-C-G	TSC2	c.5357C>G	p.P1786R	Missense	42/42	-
19-1226602-G-T	STK11	c.1258G>T	p.A420S	Missense	9/10	-
17-41243473-G-C	BRCA1	c.4075C>G	p.Q1359E	Missense	10/23	-
19-41765775-C-T	AXL	c.2651C>T	p.S884F	Missense	20/20	-
16-2124210-G-A	TSC2	c.2365G>A	p.V789I	Missense	22/42	-
2-29416646-C-T	ALK	c.4307G>A	p.R1436H	Missense	29/29	-
2-29416520-A-G	ALK	c.4433T>C	p.M1478T	Missense	29/29	-
2-212251659-C-A	ERBB4	c.3400G>T	p.V1134L	Missense	27/28	-
2-212248518-C-G	ERBB4	c.3749G>C	p.R1250P	Missense	28/28	-
16-1555592-G-A	TELO2	c.2024G>A	p.R675Q	Missense	16/21	-
19-44058922-G-A	XRCC1	c.290C>T	p.S97F	Missense	4/17	-
2-225343000-C-T	CUL3	c.2092G>A	p.D698N	Missense	15/16	-
2-212251874-T-C	ERBB4	c.3185A>G	p.N1062S	Missense	27/28	-
4-175899071-GTGACACCCTCCCAGAGGCAACCTCAGT-G	ADAM29	c.2399_2425del27	p.T800_L808del	InFrameDeletion	5/5	-
6-152129480-G-A	ESR1	c.433G>A	p.G145S	Missense	1/8	-
9-98209357-C-T	PTCH1	c.4181G>A	p.R1394Q	Missense	23/24	-
9-98209328-T-C	PTCH1	c.4210A>G	p.T1404A	Missense	23/24	-
9-98209366-C-T	PTCH1	c.4172G>A	p.R1391Q	Missense	23/24	-
7-42005105-C-T	GLI3	c.3566G>A	p.R1189H	Missense	15/15	-
7-42005498-C-A	GLI3	c.3173G>T	p.R1058L	Missense	15/15	-
7-128851988-C-A	SMO	c.2060C>A	p.P687Q	Missense	12/12	-
17-7576916-G-GA	TP53	c.929_930insT	p.N311Qfs*26	Frameshift	9/11	-
7-141429371-T-G	WEE2	c.1576T>G	p.Y526D	Missense	11/12	-
7-55259532-G-C	EGFR	c.2590G>C	p.A864P	Missense	21/28	-
8-37695353-G-A	ADGRA2	c.2155G>A	p.G719R	Missense	14/19	-
7-116436092-G-A	MET	c.4087G>A	p.A1363T	Missense	21/21	-
20-52188287-GT-G	ZNF217	c.3142delA	p.T1048Lfs*59	Frameshift	5/6	-
12-124824652-G-A	NCOR2	c.5587C>T	p.R1863W	Missense	39/49	-
17-7577524-T-G	TP53	c.757A>C	p.T253P	Missense	7/11	-
12-121434531-C-A	HNF1A	c.1295C>A	p.S432Y	Missense	6/10	-
22-42522737-C-T	CYP2D6	c.1333G>A	p.G445R	Missense	9/9	-
17-7579407-ACAGGGGCCAGGAGGGGGCTGGTG-A	TP53	c.257_279del23	p.A86Vfs*55	Frameshift	4/11	-
4-187521337-T-C	FAT1	c.11818A>G	p.T3940A	Missense	22/27	-
12-124824739-T-TGCCG	NCOR2	c.5499_5500insCGGC	p.S1834Rfs*194	Frameshift	39/49	-
17-7577152-AC-A	TP53	c.785delG	p.G262Vfs*83	Frameshift	8/11	-
4-88977295-C-T	PKD2	c.1774C>T	p.R592*	Nonsense	8/15	-
9-98240437-G-C	PTCH1	c.1247C>G	p.T416S	Missense	9/24	-
4-187524600-C-T	FAT1	c.11080G>A	p.V3694I	Missense	19/27	-
7-42007293-C-A	GLI3	c.2332G>T	p.V778L	Missense	14/15	-
15-67482843-C-T	SMAD3	c.1247C>T	p.S416F	Missense	9/9	-
15-67473780-G-T	SMAD3	c.860G>T	p.R287L	Missense	6/9	-
19-1219336-G-T	STK11	c.388G>T	p.E130*	Nonsense	3/10	-
13-32914356-C-T	BRCA2	c.5864C>T	p.S1955L	Missense	11/27	-
19-50905089-T-C	POLD1	c.371T>C	p.V124A	Missense	4/27	-
17-41226368-T-C	BRCA1	c.4655A>G	p.Y1552C	Missense	14/23	-
3-10116221-C-T	FANCD2	c.2723C>T	p.T908I	Missense	29/44	-
1-156838380-C-T	NTRK1	c.658C>T	p.R220W	Missense	6/17	-
7-55231464-A-T	EGFR	c.1670A>T	p.Q557L	Missense	14/28	-
9-5534876-G-T	PDCD1LG2	c.187G>T	p.E63*	Nonsense	3/7	-
12-133254172-T-A	POLE	c.712A>T	p.I238F	Missense	7/49	-
16-2133780-C-T	TSC2	c.3968C>T	p.A1323V	Missense	33/42	-
3-10076461-G-A	FANCD2	c.356G>A	p.R119H	Missense	5/44	-
1-27057761-C-T	ARID1A	c.1469C>T	p.P490L	Missense	3/20	-
9-5557694-C-A	PDCD1LG2	c.708C>A	p.F236L	Missense	5/7	-
2-47705647-A-G	MSH2	c.2447A>G	p.Q816R	Missense	14/16	-
12-49426729-AGCT-A	KMT2D	c.11756_11758delAGC	p.Q3919del	InFrameDeletion	40/55	-
2-47635594-T-C	MSH2	c.266T>C	p.V89A	Missense	2/16	-
12-133219820-A-G	POLE	c.4541T>C	p.V1514A	Missense	35/49	-
17-66521912-A-C	PRKAR1A	c.567A>C	p.E189D	Missense	7/11	-
15-91298125-G-A	BLM	c.1044G>A	p.M348I	Missense	5/22	-
17-7577103-C-A	TP53	c.835G>T	p.G279W	Missense	8/11	-
9-21971123-TGA-T	CDKN2A	c.233_234delTC	p.L78Hfs*41	Frameshift	2/3	-
5-112175945-G-T	APC	c.4654G>T	p.E1552*	Nonsense	16/16	-
20-52193658-C-T	ZNF217	c.1645G>A	p.A549T	Missense	4/6	-
17-7578224-CT-C	TP53	c.625delA	p.R209Efs*38	Frameshift	6/11	-
17-7578249-AT-A	TP53	c.599delA	p.N200Ifs*47	Frameshift	6/11	-
9-98241386-G-A	PTCH1	c.1111C>T	p.Q371*	Nonsense	8/24	-
3-142285065-T-C	ATR	c.190A>G	p.T64A	Missense	3/47	-
2-48030630-C-T	MSH6	c.3244C>T	p.P1082S	Missense	5/10	-
18-19751656-G-A	GATA6	c.551G>A	p.S184N	Missense	2/7	-
5-112176548-G-C	APC	c.5257G>C	p.A1753P	Missense	16/16	-
4-106164794-G-C	TET2	c.3662G>C	p.C1221S	Missense	6/11	-
11-118375998-G-A	KMT2A	c.9391G>A	p.G3131S	Missense	27/36	-
16-9934956-G-A	GRIN2A	c.1334C>T	p.S445L	Missense	6/13	-
3-30713433-G-T	TGFBR2	c.758G>T	p.G253V	Missense	4/7	-
13-73346013-C-A	DIS3	c.1525G>T	p.V509L	Missense	11/21	-
4-187540134-C-A	FAT1	c.7606G>T	p.A2536S	Missense	10/27	-
6-18134076-T-A	TPMT	c.539A>T	p.Y180F	Missense	7/9	-
2-141250219-C-A	LRP1B	c.9078G>T	p.R3026S	Missense	57/91	-
3-89462320-G-T	EPHA3	c.1792G>T	p.D598Y	Missense	10/17	-
4-25667818-G-A	SLC34A2	c.448G>A	p.G150R	Missense	5/13	-
2-47630409-C-G	MSH2	c.79C>G	p.P27A	Missense	1/16	-
1-241676979-C-T	FH	c.302G>A	p.R101Q	Missense	3/10	-
16-23634361-C-G	PALB2	c.2925G>C	p.R975S	Missense	9/13	-
7-42084984-A-G	GLI3	c.825T>C	p.D275=	Synonymous	6/15	-
9-139401405-C-T	NOTCH1	c.3664G>A	p.V1222M	Missense	23/34	-
19-15302951-G-A	NOTCH3	c.499C>T	p.P167S	Missense	4/33	-
9-135781505-G-C	TSC1	c.1460C>G	p.S487C	Missense	15/23	-
17-78360160-G-A	RNF213	c.14650G>A	p.V4884I	Missense	62/68	-
9-21971092-C-A	CDKN2A	c.266G>T	p.G89V	Missense	2/3	-
2-178098816-C-G	NFE2L2	c.229G>C	p.D77H	Missense	2/5	-
19-11141502-G-T	SMARCA4	c.3479G>T	p.G1160V	Missense	25/35	-
1-120612013-GC-AA	NOTCH2	c.7_8delGCinsTT	p.A3F	Missense	1/34	-
1-97700547-G-T	DPYD	c.2303C>A	p.T768K	Missense	19/23	-
2-141819820-C-A	LRP1B	c.1036G>T	p.G346W	Missense	8/91	-
3-41266495-A-G	CTNNB1	c.292A>G	p.M98V	Missense	4/15	-
7-55273231-G-T	EGFR	c.3554G>T	p.G1185V	Missense	28/28	-
3-178938922-G-A	PIK3CA	c.2164G>A	p.E722K	Missense	14/21	-
1-158646019-G-T	SPTA1	c.1024C>A	p.Q342K	Missense	8/52	-
19-11152043-C-T	SMARCA4	c.4231C>T	p.R1411W	Missense	30/35	-
10-89685303-G-C	PTEN	c.198G>C	p.K66N	Missense	3/9	-
2-178095985-C-T	NFE2L2	c.1346G>A	p.R449H	Missense	5/5	-
19-11144121-C-G	SMARCA4	c.3702C>G	p.F1234L	Missense	26/35	-
19-11129655-G-A	SMARCA4	c.2461G>A	p.E821K	Missense	17/35	-
9-139391526-G-A	NOTCH1	c.6665C>T	p.P2222L	Missense	34/34	-
19-11096931-C-T	SMARCA4	c.422C>T	p.S141L	Missense	4/35	-
1-158651439-G-A	SPTA1	c.409C>T	p.R137C	Missense	4/52	-
19-18280037-C-T	PIK3R2	c.2120C>T	p.A707V	Missense	16/16	-
2-25467408-C-T	DNMT3A	c.1667+1G>A	-	IntronicSNV	-	14/22
3-89448631-G-C	EPHA3	c.1594+1G>C	-	IntronicSNV	-	7/16
12-46125084-C-T	ARID2	c.271C>T	p.Q91*	Nonsense	3/21	-
10-70333863-C-T	TET1	c.1768C>T	p.R590*	Nonsense	2/12	-
13-49039386-A-T	RB1	c.2371A>T	p.K791*	Nonsense	23/27	-
21-36206817-C-A	RUNX1	c.695G>T	p.R232L	Missense	7/9	-
17-7577017-A-C	TP53	c.919+2T>G	-	IntronicSNV	-	8/10
16-2133701-G-A	TSC2	c.3889G>A	p.A1297T	Missense	33/42	-
1-156830767-G-A	NTRK1	c.41G>A	p.S14N	Missense	1/17	-
17-47696345-C-T	SPOP	c.478G>A	p.E160K	Missense	5/10	-
10-8100756-C-A	GATA3	c.730C>A	p.P244T	Missense	3/6	-
15-50784950-C-T	USP8	c.2287C>T	p.R763W	Missense	15/20	-
12-133241030-C-A	POLE	c.2487G>T	p.M829I	Missense	22/49	-
3-142268488-G-C	ATR	c.3004C>G	p.L1002V	Missense	15/47	-
16-23641488-G-A	PALB2	c.1987C>T	p.R663C	Missense	5/13	-
2-48030591-G-C	MSH6	c.3205G>C	p.G1069R	Missense	5/10	-
5-235284-G-A	SDHA	c.1090G>A	p.V364I	Missense	9/15	-
13-32907206-A-G	BRCA2	c.1591A>G	p.K531E	Missense	10/27	-
13-32913339-T-G	BRCA2	c.4847T>G	p.L1616*	Nonsense	11/27	-
16-3786715-A-G	CREBBP	c.4496T>C	p.L1499P	Missense	27/31	-
16-23634390-T-C	PALB2	c.2896A>G	p.I966V	Missense	9/13	-
11-118344275-C-T	KMT2A	c.2401C>T	p.H801Y	Missense	3/36	-
5-112102900-A-G	APC	c.235A>G	p.S79G	Missense	4/16	-
3-138417834-C-T	PIK3CB	c.1685G>A	p.R562Q	Missense	13/24	-
4-143159104-C-T	INPP4B	c.749G>A	p.R250Q	Missense	12/26	-
X-53246390-G-A	KDM5C	c.592C>T	p.R198*	Nonsense	5/26	-
16-23646296-G-C	PALB2	c.1571C>G	p.S524*	Nonsense	4/13	-
7-151216551-G-A	RHEB	c.47C>T	p.S16F	Missense	1/8	-
4-55524218-G-A	KIT	c.37G>A	p.V13I	Missense	1/21	-
7-151932990-C-T	KMT2C	c.2681G>A	p.R894Q	Missense	16/59	-
21-36421175-C-G	RUNX1	c.22G>C	p.E8Q	Missense	2/9	-
11-108098419-G-A	ATM	c.68G>A	p.R23Q	Missense	2/63	-
19-54656314-G-A	CNOT3	c.1855G>A	p.E619K	Missense	15/18	-
X-70360679-GGCA-G	MED12	c.6256_6258delCAG	p.Q2086del	InFrameDeletion	42/45	-
17-7579409-CA-C	TP53	c.278delT	p.L93Rfs*30	Frameshift	4/11	-
11-2154241-TG-T	IGF2	c.518delC	p.P173Qfs*27	Frameshift	4/4	-
9-97864071-C-T	FANCC	c.1595G>A	p.R532K	Missense	15/15	-
16-3801807-C-G	CREBBP	c.3699G>C	p.R1233S	Missense	20/31	-
2-48028222-C-T	MSH6	c.3100C>T	p.R1034W	Missense	4/10	-
1-27059197-G-T	ARID1A	c.1834G>T	p.A612S	Missense	4/20	-
16-3779205-G-A	CREBBP	c.5843C>T	p.P1948L	Missense	31/31	-
1-78428481-G-A	FUBP1	c.1318C>T	p.R440W	Missense	14/20	-
11-532738-G-C	HRAS	c.468C>G	p.F156L	Missense	5/6	-
1-156841515-G-A	NTRK1	c.818G>A	p.R273Q	Missense	7/17	-
16-23637693-T-C	PALB2	c.2612A>G	p.D871G	Missense	7/13	-
5-228417-A-G	SDHA	c.739A>G	p.I247V	Missense	6/15	-
12-49441815-G-GC	KMT2D	c.4168_4168dup	p.A1390Gfs*42	Frameshift	15/55	-
19-11144147-G-T	SMARCA4	c.3728G>T	p.R1243L	Missense	26/35	-
1-27059213-C-A	ARID1A	c.1850C>A	p.S617*	Nonsense	4/20	-
1-27059213-C-G	ARID1A	c.1850C>G	p.S617*	Nonsense	4/20	-
2-141072604-C-A	LRP1B	c.12705G>T	p.L4235F	Missense	83/91	-
12-49426972-TG-T	KMT2D	c.11515delC	p.Q3839Sfs*42	Frameshift	40/55	-
17-29588782-C-T	NF1	c.4631C>T	p.A1544V	Missense	35/58	-
2-16082638-G-A	MYCN	c.452G>A	p.G151E	Missense	2/3	-
1-11307790-C-G	MTOR	c.1117G>C	p.V373L	Missense	8/58	-
16-23646541-A-T	PALB2	c.1326T>A	p.N442K	Missense	4/13	-
2-47600986-G-A	EPCAM	c.224G>A	p.G75D	Missense	3/9	-
15-42054402-G-A	MGA	c.7586G>A	p.R2529K	Missense	22/24	-
16-23647577-G-T	PALB2	c.290C>A	p.S97Y	Missense	4/13	-
16-23647548-A-T	PALB2	c.319T>A	p.F107I	Missense	4/13	-
9-139418358-C-T	NOTCH1	c.214G>A	p.G72R	Missense	3/34	-
9-98224149-C-T	PTCH1	c.2692G>A	p.D898N	Missense	16/24	-
2-17955667-C-T	GEN1	c.1201C>T	p.R401*	Nonsense	11/14	-
11-108139218-G-T	ATM	c.2720G>T	p.C907F	Missense	18/63	-
15-91354582-C-T	BLM	c.4022C>T	p.A1341V	Missense	21/22	-
11-108196147-C-T	ATM	c.6683C>T	p.T2228I	Missense	46/63	-
14-95579436-G-A	DICER1	c.2033C>T	p.S678F	Missense	12/27	-
22-29095911-T-C	CHEK2	c.923A>G	p.E308G	Missense	9/15	-
16-23649402-C-T	PALB2	c.97G>A	p.A33T	Missense	2/13	-
19-2202745-C-T	DOT1L	c.754C>T	p.Q252*	Nonsense	9/28	-
19-50919693-C-T	POLD1	c.2861C>T	p.T954M	Missense	23/27	-
13-28611358-C-T	FLT3	c.1273G>A	p.A425T	Missense	10/24	-
5-223642-G-A	SDHA	c.109G>A	p.V37I	Missense	2/15	-
5-112174667-A-G	APC	c.3376A>G	p.S1126G	Missense	16/16	-
6-43746655-A-G	VEGFA	c.962A>G	p.K321R	Missense	5/8	-
9-133759794-G-T	ABL1	c.2117G>T	p.G706V	Missense	11/11	-
14-95582861-T-C	DICER1	c.1681A>G	p.I561V	Missense	10/27	-
5-112175007-G-A	APC	c.3716G>A	p.R1239K	Missense	16/16	-
2-215645591-C-T	BARD1	c.1007G>A	p.C336Y	Missense	4/11	-
8-139163927-G-A	FAM135B	c.2791C>T	p.Q931*	Nonsense	13/20	-
15-50784955-C-G	USP8	c.2292C>G	p.N764K	Missense	15/20	-
22-21336775-G-A	LZTR1	c.115G>A	p.E39K	Missense	1/21	-
2-16086016-C-T	MYCN	c.1192C>T	p.R398W	Missense	3/3	-
11-108122627-G-T	ATM	c.1671G>T	p.M557I	Missense	11/63	-
2-30143140-C-A	ALK	c.386G>T	p.G129V	Missense	1/29	-
4-55127370-G-C	PDGFRA	c.158G>C	p.S53T	Missense	3/23	-
18-48591865-C-A	SMAD4	c.1028C>A	p.S343*	Nonsense	9/12	-
2-141625202-C-A	LRP1B	c.4536G>T	p.Q1512H	Missense	27/91	-
5-79950724-G-GCCGCAGCGGCCGCAGCGC	MSH3	c.186_187insGCCGCAGCGCCCGCAGCG	p.A62_P63insAAAPAA	InFrameInsertion	1/24	-
12-12022747-G-A	ETV6	c.853G>A	p.V285M	Missense	5/8	-
9-87635188-C-T	NTRK2	c.2240C>T	p.T747M	Missense	18/19	-
8-139153531-G-A	FAM135B	c.3700C>T	p.R1234W	Missense	17/20	-
19-50905288-C-T	POLD1	c.496C>T	p.R166W	Missense	5/27	-
2-141081590-T-C	LRP1B	c.12386A>G	p.Y4129C	Missense	81/91	-
20-31023070-C-A	ASXL1	c.2555C>A	p.S852*	Nonsense	13/13	-
15-66727451-CAGAAGCAGAAGGTGG-C	MAP2K1	c.167_181del15	p.Q56_G61delinsR	MultiAAMissense	2/11	-
16-23641736-T-C	PALB2	c.1739A>G	p.Y580C	Missense	5/13	-
16-23634425-T-C	PALB2	c.2861A>G	p.E954G	Missense	9/13	-
7-6026636-C-T	PMS2	c.1760G>A	p.S587N	Missense	11/15	-
17-59858307-T-C	BRIP1	c.1688A>G	p.D563G	Missense	12/20	-
7-81334774-C-G	HGF	c.1942G>C	p.G648R	Missense	17/18	-
16-9858370-G-A	GRIN2A	c.3031C>T	p.R1011W	Missense	13/13	-
5-11385274-CGCG-C	CTNND2	c.677_679delCGC	p.P226del	InFrameDeletion	7/22	-
8-139164546-G-T	FAM135B	c.2172C>A	p.H724Q	Missense	13/20	-
15-91312406-A-G	BLM	c.2351A>G	p.Y784C	Missense	11/22	-
19-10602748-G-A	KEAP1	c.830C>T	p.T277M	Missense	3/6	-
2-48026609-G-A	MSH6	c.1487G>A	p.C496Y	Missense	4/10	-
19-1219381-G-T	STK11	c.433G>T	p.E145*	Nonsense	3/10	-
3-134825379-C-A	EPHB1	c.895C>A	p.P299T	Missense	4/16	-
1-3342296-G-T	PRDM16	c.3091G>T	p.E1031*	Nonsense	13/17	-
1-241682991-G-C	FH	c.32C>G	p.S11W	Missense	1/10	-
16-23647094-C-T	PALB2	c.773G>A	p.S258N	Missense	4/13	-
3-10088285-T-G	FANCD2	c.1156T>G	p.F386V	Missense	15/44	-
7-73513529-G-C	LIMK1	c.569G>C	p.G190A	Missense	5/16	-
16-2124355-C-G	TSC2	c.2510C>G	p.A837G	Missense	22/42	-
4-55964373-C-T	KDR	c.2440G>A	p.D814N	Missense	17/30	-
17-66526086-G-A	PRKAR1A	c.917G>A	p.R306Q	Missense	10/11	-
14-81609975-T-C	TSHR	c.1573T>C	p.F525L	Missense	10/10	-
9-35074166-G-A	FANCG	c.1808C>T	p.S603F	Missense	14/14	-
12-25398213-T-A	KRAS	c.106A>T	p.I36L	Missense	2/5	-
11-32450067-G-T	WT1	c.760C>A	p.P254T	missense_variant	2/10	-
5-131924538-A-G	RAD50	c.1211A>G	p.Q404R	Missense	8/25	-
17-59820429-T-C	BRIP1	c.2324A>G	p.N775S	Missense	16/20	-
16-89836354-G-A	FANCA	c.2395C>T	p.P799S	Missense	26/43	-
16-89849320-T-C	FANCA	c.1573A>G	p.I525V	Missense	17/43	-
17-33325636-C-T	LIG3	c.2003C>T	p.P668L	Missense	14/20	-
16-23649233-T-G	PALB2	c.149A>C	p.K50T	Missense	3/13	-
13-34392361-C-G	RFC3	c.46C>G	p.L16V	Missense	1/9	-
9-35079467-T-C	FANCG	c.55A>G	p.K19E	Missense	1/14	-
17-41197702-T-A	BRCA1	c.5585A>T	p.H1862L	Missense	23/23	-
12-46245317-CAG-C	ARID2	c.3411_3412delAG	p.G1139Sfs*20	Frameshift	15/21	-
15-91346870-T-C	BLM	c.3478T>C	p.Y1160H	Missense	18/22	-
4-1369242-C-T	UVSSA	c.1379C>T	p.A460V	Missense	9/14	-
4-87671947-C-T	PTPN13	c.2975C>T	p.P992L	Missense	18/48	-
16-23641332-C-T	PALB2	c.2143G>A	p.D715N	Missense	5/13	-
16-23646878-T-C	PALB2	c.989A>G	p.N330S	Missense	4/13	-
5-67591145-ATACTTGATGT-A	PIK3R1	c.1738_1745+2delTACTTGATGT	-	SpliceDonorDeletion	13/16	13/15
19-11123788-C-T	SMARCA4	c.2438C>T	p.S813L	Missense	16/35	-
1-158596707-C-A	SPTA1	c.5755G>T	p.A1919S	Missense	41/52	-
4-25677901-ATCT-A	SLC34A2	c.1612_1614delTTC	p.F538del	InFrameDeletion	13/13	-
3-52623085-C-G	PBRM1	c.2965+1G>C	-	IntronicSNV	-	19/29
7-140508704-C-T	BRAF	c.596G>A	p.R199K	Missense	4/18	-
12-49431142-G-A	KMT2D	c.9997C>T	p.Q3333*	Nonsense	35/55	-
15-91310200-C-G	BLM	c.2254C>G	p.Q752E	Missense	10/22	-
3-183225879-C-A	KLHL6	c.877G>T	p.E293*	Nonsense	3/7	-
15-88678508-C-A	NTRK3	c.1028G>T	p.R343L	Missense	10/20	-
19-10602257-C-A	KEAP1	c.1321G>T	p.E441*	Nonsense	3/6	-
5-24535297-C-A	CDH10	c.738G>T	p.M246I	Missense	5/12	-
19-1207045-C-T	STK11	c.133C>T	p.L45F	Missense	1/10	-
13-48951166-C-G	RB1	c.1328C>G	p.S443*	Nonsense	13/27	-
3-183217537-C-T	KLHL6	c.988G>A	p.D330N	Missense	4/7	-
5-24509793-C-A	CDH10	c.1138G>T	p.E380*	Nonsense	7/12	-
12-124885199-G-A	NCOR2	c.1661C>T	p.S554L	Missense	17/49	-
2-141812693-G-T	LRP1B	c.1544C>A	p.S515*	Nonsense	10/91	-
20-40733255-C-A	PTPRT	c.3494G>T	p.R1165M	Missense	25/31	-
8-139153549-G-T	FAM135B	c.3682C>A	p.L1228I	Missense	17/20	-
17-29683579-G-T	NF1	c.7717G>T	p.A2573S	Missense	52/58	-
2-141108376-C-A	LRP1B	c.11882G>T	p.S3961I	Missense	77/91	-
2-141055406-G-T	LRP1B	c.12938C>A	p.P4313Q	Missense	84/91	-
1-150551619-C-T	MCL1	c.388G>A	p.E130K	Missense	1/3	-
12-57559904-G-T	LRP1	c.2709G>T	p.E903D	Missense	17/89	-
2-141773407-C-A	LRP1B	c.2048G>T	p.G683V	Missense	13/91	-
1-158637678-C-A	SPTA1	c.2008G>T	p.E670*	Nonsense	15/52	-
4-20482357-G-T	SLIT2	c.486G>T	p.Q162H	Missense	6/37	-
12-57571248-G-T	LRP1	c.4235G>T	p.R1412L	Missense	26/89	-
9-139397646-C-A	NOTCH1	c.5155G>T	p.E1719*	Nonsense	27/34	-
7-142658027-G-A	KEL	c.388C>T	p.R130W	Missense	4/19	-
4-55570043-A-G	KIT	c.910A>G	p.T304A	Missense	5/21	-
4-55133537-A-G	PDGFRA	c.841A>G	p.T281A	Missense	6/23	-
4-20469422-G-T	SLIT2	c.443G>T	p.R148L	Missense	5/37	-
4-55146592-G-A	PDGFRA	c.2266G>A	p.D756N	Missense	16/23	-
22-21336817-C-T	LZTR1	c.157C>T	p.R53C	Missense	1/21	-
22-24143216-A-G	SMARCB1	c.448A>G	p.T150A	Missense	4/9	-
X-47034471-C-T	RBM10	c.556C>T	p.R186*	Nonsense	6/24	-
3-10183835-C-T	VHL	c.304C>T	p.P102S	Missense	1/3	-
5-24537654-C-A	CDH10	c.361G>T	p.E121*	Nonsense	3/12	-
2-16082736-G-T	MYCN	c.550G>T	p.A184S	Missense	2/3	-
22-29091732-C-T	CHEK2	c.1225G>A	p.D409N	Missense	11/15	-
1-158609722-C-G	SPTA1	c.4813G>C	p.E1605Q	Missense	34/52	-
9-2039815-GCAA-G	SMARCA2	c.708_710delACA	p.Q238del	InFrameDeletion	4/34	-
16-2134692-A-G	TSC2	c.4469A>G	p.E1490G	Missense	34/42	-
19-11169554-G-T	SMARCA4	c.4624G>T	p.E1542*	Nonsense	32/35	-
9-98241377-C-A	PTCH1	c.1120G>T	p.E374*	Nonsense	8/24	-
1-158592778-G-T	SPTA1	c.6115C>A	p.Q2039K	Missense	43/52	-
3-178938908-A-G	PIK3CA	c.2150A>G	p.D717G	Missense	14/21	-
7-116415105-C-A	MET	c.3199C>A	p.Q1067K	Missense	15/21	-
2-100024580-C-G	REV1	c.2359G>C	p.D787H	Missense	15/23	-
1-16257043-G-T	SPEN	c.4308G>T	p.L1436F	Missense	11/15	-
1-158654938-A-G	SPTA1	c.224T>C	p.I75T	Missense	2/52	-
17-29509666-G-GA	NF1	c.872_872dup	p.N292Kfs*5	Frameshift	8/58	-
10-89720868-AT-A	PTEN	c.1023delT	p.F341Lfs*3	Frameshift	8/9	-
22-19279131-G-T	CLTCL1	c.34C>A	p.H12N	Missense	1/33	-
1-120459214-C-T	NOTCH2	c.6131G>A	p.R2044H	Missense	34/34	-
1-158605704-G-A	SPTA1	c.5431C>T	p.R1811*	Nonsense	38/52	-
17-7579340-G-C	TP53	c.347C>G	p.S116C	Missense	4/11	-
19-1220410-A-T	STK11	c.503A>T	p.H168L	Missense	4/10	-
13-34398073-T-A	RFC3	c.245T>A	p.I82N	Missense	3/9	-
11-69456106-G-A	CCND1	c.25G>A	p.E9K	Missense	1/5	-
16-23646559-C-A	PALB2	c.1308G>T	p.K436N	Missense	4/13	-
2-47635629-G-C	MSH2	c.301G>C	p.E101Q	Missense	2/16	-
11-108119818-T-A	ATM	c.1224T>A	p.D408E	Missense	9/63	-
16-23652436-C-A	PALB2	c.43G>T	p.E15*	Nonsense	1/13	-
17-29554310-G-T	NF1	c.2325+1G>T	-	IntronicSNV	-	19/57
9-98221936-G-A	PTCH1	c.2833C>T	p.R945*	Nonsense	17/24	-
2-173420900-C-T	PDK1	c.22C>T	p.R8C	Missense	1/11	-
19-10597488-T-C	KEAP1	c.1715A>G	p.Y572C	Missense	6/6	-
9-98240371-C-T	PTCH1	c.1313G>A	p.S438N	Missense	9/24	-
13-110435327-G-A	IRS2	c.3074C>T	p.P1025L	Missense	1/2	-
15-88678617-C-T	NTRK3	c.919G>A	p.V307M	Missense	10/20	-
9-2186225-G-A	SMARCA2	c.4591G>A	p.E1531K	Missense	32/34	-
2-178098977-A-G	NFE2L2	c.68T>C	p.L23P	Missense	2/5	-
5-149510201-C-T	PDGFRB	c.1268G>A	p.S423N	Missense	9/23	-
7-148544344-C-A	EZH2	c.47G>T	p.R16L	Missense	2/20	-
X-47041699-A-T	RBM10	c.1924A>T	p.K642*	Nonsense	17/24	-
17-29552189-G-A	NF1	c.1922G>A	p.S641N	Missense	17/58	-
16-72829710-G-A	ZFHX3	c.6871C>T	p.Q2291*	Nonsense	9/10	-
21-36164646-G-A	RUNX1	c.1229C>T	p.S410L	Missense	9/9	-
4-187541988-T-C	FAT1	c.5752A>G	p.I1918V	Missense	10/27	-
13-48941684-G-T	RB1	c.994G>T	p.D332Y	Missense	10/27	-
7-148464815-G-A	CUL1	c.1057G>A	p.E353K	Missense	9/22	-
16-3778455-A-T	CREBBP	c.6593T>A	p.L2198Q	Missense	31/31	-
3-142297514-C-T	ATR	c.33G>A	p.M11I	Missense	1/47	-
3-134920337-G-A	EPHB1	c.2152G>A	p.V718M	Missense	12/16	-
17-7578371-C-G	TP53	c.559G>C	p.G187R	Missense	5/11	-
5-180039609-C-T	FLT4	c.3434G>A	p.R1145H	Missense	26/30	-
12-56480335-T-C	ERBB3	c.442T>C	p.Y148H	Missense	4/28	-
2-30143341-G-C	ALK	c.185C>G	p.S62W	Missense	1/29	-
16-23614908-C-T	PALB2	c.3433G>A	p.G1145S	Missense	13/13	-
16-2122886-G-A	TSC2	c.2257G>A	p.A753T	Missense	21/42	-
X-47041723-C-T	RBM10	c.1948C>T	p.Q650*	Nonsense	17/24	-
22-41560115-G-T	EP300	c.3787G>T	p.E1263*	Nonsense	22/31	-
11-94204896-G-A	MRE11	c.689C>T	p.P230L	Missense	8/20	-
4-187628266-G-A	FAT1	c.2716C>T	p.Q906*	Nonsense	2/27	-
6-138199888-G-A	TNFAIP3	c.1306G>A	p.G436R	Missense	7/9	-
2-29462617-T-C	ALK	c.2284A>G	p.I762V	Missense	13/29	-
19-10610178-G-A	KEAP1	c.532C>T	p.Q178*	Nonsense	2/6	-
9-21971098-C-T	CDKN2A	c.260G>A	p.R87Q	Missense	2/3	-
7-116414971-G-A	MET	c.3065G>A	p.R1022Q	Missense	15/21	-
1-11199373-C-G	MTOR	c.5118G>C	p.K1706N	Missense	36/58	-
12-49426355-G-A	KMT2D	c.12133C>T	p.Q4045*	Nonsense	40/55	-
16-72821609-G-GCCA	ZFHX3	c.10565_10566insTGG	p.G3527dup	InFrameInsertion	10/10	-
2-30142927-C-G	ALK	c.599G>C	p.R200T	Missense	1/29	-
1-11303223-G-A	MTOR	c.1360C>T	p.R454C	Missense	9/58	-
5-176523292-G-A	FGFR4	c.1949G>A	p.R650H	Missense	15/18	-
7-142459771-G-A	PRSS1	c.347G>A	p.R116H	Missense	3/5	-
13-48955457-G-A	RB1	c.1573G>A	p.A525T	Missense	17/27	-
9-98238342-G-C	PTCH1	c.1702C>G	p.P568A	Missense	12/24	-
3-10107658-C-T	FANCD2	c.2380C>T	p.R794*	Nonsense	25/44	-
16-89874739-C-G	FANCA	c.559G>C	p.V187L	Missense	6/43	-
2-29455173-C-T	ALK	c.2629G>A	p.A877T	Missense	15/29	-
X-39933640-G-A	BCOR	c.959C>T	p.A320V	Missense	4/15	-
12-69207406-G-C	MDM2	c.172G>C	p.E58Q	Missense	3/11	-
22-41489069-C-G	EP300	c.61C>G	p.P21A	Missense	1/31	-
9-93626926-C-T	SYK	c.773C>T	p.P258L	Missense	5/14	-
11-119155706-A-G	CBL	c.1459A>G	p.M487V	Missense	10/16	-
3-134644700-G-T	EPHB1	c.101G>T	p.W34L	Missense	2/16	-
2-178098882-C-G	NFE2L2	c.163G>C	p.E55Q	Missense	2/5	-
7-151859653-T-C	KMT2C	c.11009A>G	p.N3670S	Missense	43/59	-
6-152265484-G-A	ESR1	c.937G>A	p.D313N	Missense	4/8	-
17-41244901-C-T	BRCA1	c.2647G>A	p.A883T	Missense	10/23	-
17-7578457-GC-G	TP53	c.473delG	p.R158Pfs*12	Frameshift	5/11	-
X-70356243-G-T	MED12	c.5138G>T	p.R1713L	Missense	37/45	-
7-81374372-C-A	HGF	c.690G>T	p.K230N	Missense	6/18	-
17-7577035-CT-C	TP53	c.903delA	p.S303Afs*42	Frameshift	8/11	-
16-23632737-T-C	PALB2	c.3059A>G	p.Q1020R	Missense	10/13	-
16-23632714-C-G	PALB2	c.3082G>C	p.G1028R	Missense	10/13	-
1-156838353-G-A	NTRK1	c.631G>A	p.V211M	Missense	6/17	-
13-26928012-G-A	CDK8	c.451G>A	p.D151N	Missense	4/13	-
16-11348892-G-T	SOCS1	c.444C>A	p.F148L	Missense	2/2	-
1-11190590-G-C	MTOR	c.5609C>G	p.T1870S	Missense	39/58	-
19-19257570-C-T	MEF2B	c.656G>A	p.R219Q	Missense	6/9	-
3-89499444-G-A	EPHA3	c.2614G>A	p.E872K	Missense	15/17	-
12-46246523-T-TA	ARID2	c.4618dupA	p.T1540Nfs*4	Frameshift	15/21	-
2-47698140-T-A	MSH2	c.1698T>A	p.N566K	Missense	11/16	-
16-23641422-TG-T	PALB2	c.2052delC	p.R686Gfs*23	Frameshift	5/13	-
1-27023762-A-G	ARID1A	c.868A>G	p.T290A	Missense	1/20	-
10-43612057-G-A	RET	c.2162G>A	p.R721Q	Missense	12/20	-
17-37618715-G-A	CDK12	c.391G>A	p.E131K	Missense	1/14	-
10-43572762-T-C	RET	c.56T>C	p.L19P	Missense	1/20	-
5-131978019-A-G	RAD50	c.3902A>G	p.K1301R	Missense	25/25	-
2-141294168-C-A	LRP1B	c.7624G>T	p.E2542*	Nonsense	46/91	-
1-11199444-G-A	MTOR	c.5047C>T	p.R1683W	Missense	36/58	-
12-133218901-G-A	POLE	c.5035C>T	p.R1679C	Missense	38/49	-
10-70450664-C-T	TET1	c.5504C>T	p.P1835L	Missense	12/12	-
15-91310239-G-A	BLM	c.2293G>A	p.V765I	Missense	10/22	-
6-106552940-G-A	PRDM1	c.905G>A	p.R302Q	Missense	5/7	-
2-25459868-C-A	DNMT3A	c.2415G>T	p.L805F	Missense	21/23	-
17-7577048-T-G	TP53	c.890A>C	p.H297P	Missense	8/11	-
2-25459868-C-G	DNMT3A	c.2415G>C	p.L805F	Missense	21/23	-
12-12006456-A-T	ETV6	c.424A>T	p.T142S	Missense	4/8	-
12-49441815-GC-G	KMT2D	c.4168delG	p.A1390Qfs*27	Frameshift	15/55	-
21-36164607-C-T	RUNX1	c.1268G>A	p.R423H	Missense	9/9	-
2-25467139-T-C	DNMT3A	c.1736A>G	p.D579G	Missense	15/23	-
22-23596108-A-G	BCR	c.1402A>G	p.S468G	Missense	2/23	-
19-10469924-C-G	TYK2	c.2102G>C	p.R701T	Missense	15/25	-
2-25458628-G-T	DNMT3A	c.2545C>A	p.P849T	Missense	22/23	-
19-10475547-G-A	TYK2	c.1189C>T	p.R397W	Missense	8/25	-
7-140481480-C-G	BRAF	c.1328G>C	p.R443T	Missense	11/18	-
6-152332849-G-T	ESR1	c.1155G>T	p.E385D	Missense	5/8	-
7-55223636-A-C	EGFR	c.1003A>C	p.K335Q	Missense	8/28	-
11-32456683-C-T	WT1	c.209G>A	p.G75D	Missense	1/10	-
2-48027283-A-G	MSH6	c.2161A>G	p.R721G	Missense	4/10	-
2-47657008-C-G	MSH2	c.1204C>G	p.Q402E	Missense	7/16	-
3-128200062-C-T	GATA2	c.1243G>A	p.E415K	Missense	6/6	-
12-57589969-C-T	LRP1	c.8801C>T	p.S2934L	Missense	55/89	-
3-51680401-G-T	RAD54L2	c.2930G>T	p.R977L	Missense	19/23	-
6-152420091-C-A	ESR1	c.1778C>A	p.A593D	Missense	8/8	-
13-48934251-A-T	RB1	c.706A>T	p.K236*	Nonsense	7/27	-
3-37067437-G-T	MLH1	c.1348G>T	p.D450Y	Missense	12/19	-
4-187535345-C-A	FAT1	c.9229G>T	p.G3077C	Missense	12/27	-
2-48010536-C-T	MSH6	c.164C>T	p.P55L	Missense	1/10	-
1-158644175-T-C	SPTA1	c.1294A>G	p.T432A	Missense	10/52	-
16-23647106-G-A	PALB2	c.761C>T	p.S254L	Missense	4/13	-
X-39933940-G-A	BCOR	c.659C>T	p.A220V	Missense	4/15	-
10-8100582-T-C	GATA3	c.556T>C	p.Y186H	Missense	3/6	-
7-42006050-C-T	GLI3	c.2621G>A	p.R874H	Missense	15/15	-
10-8097647-G-T	GATA3	c.29G>T	p.W10L	Missense	2/6	-
16-81979858-G-A	PLCG2	c.3560G>A	p.R1187Q	Missense	31/33	-
10-8100602-C-A	GATA3	c.576C>A	p.D192E	Missense	3/6	-
8-41563662-C-T	ANK1	c.2096G>A	p.R699Q	Missense	18/43	-
18-18547759-T-C	ROCK1	c.3146A>G	p.N1049S	Missense	26/33	-
10-70332613-T-C	TET1	c.518T>C	p.I173T	Missense	2/12	-
14-95572101-G-A	DICER1	c.3007C>T	p.R1003*	Nonsense	19/27	-
21-36164539-G-A	RUNX1	c.1336C>T	p.L446F	Missense	9/9	-
3-128205181-G-C	GATA2	c.260C>G	p.P87R	Missense	3/6	-
7-55249070-A-T	EGFR	c.2368A>T	p.T790S	Missense	20/28	-
10-84745186-G-A	NRG3	c.1916G>A	p.R639Q	Missense	9/9	-
2-29432685-A-C	ALK	c.3803T>G	p.I1268S	Missense	25/29	-
12-57864192-C-T	GLI1	c.1669C>T	p.R557C	Missense	12/12	-
2-29456502-G-C	ALK	c.2416C>G	p.R806G	Missense	14/29	-
1-156834171-C-A	NTRK1	c.238C>A	p.Q80K	Missense	2/17	-
5-149499063-C-T	PDGFRB	c.2765G>A	p.R922H	Missense	20/23	-
16-23646411-T-C	PALB2	c.1456A>G	p.K486E	Missense	4/13	-
11-32439155-C-A	WT1	c.918G>T	p.W311C	Missense	4/10	-
15-91312674-C-T	BLM	c.2413C>T	p.H805Y	Missense	12/22	-
12-133245062-G-A	POLE	c.2053C>T	p.R685W	Missense	19/49	-
5-112173299-A-T	APC	c.2008A>T	p.K670*	Nonsense	16/16	-
5-251216-G-A	SDHA	c.1661G>A	p.R554Q	Missense	12/15	-
8-139209815-C-T	FAM135B	c.767G>A	p.R256H	Missense	8/20	-
19-13059959-C-T	RAD23A	c.665C>T	p.P222L	Missense	6/9	-
8-37687409-C-T	ADGRA2	c.595C>T	p.R199C	Missense	6/19	-
16-3832751-G-A	CREBBP	c.1507C>T	p.Q503*	Nonsense	6/31	-
4-187557792-C-A	FAT1	c.3919G>T	p.G1307*	Nonsense	5/27	-
8-103238196-G-A	RRM2B	c.271C>T	p.H91Y	Missense	3/9	-
6-35426107-C-T	FANCE	c.1003C>T	p.Q335*	Nonsense	5/10	-
17-1782605-G-A	RPA1	c.856G>A	p.V286I	Missense	10/17	-
17-38510626-C-T	RARA	c.880C>T	p.R294W	Missense	7/9	-
17-38510642-A-G	RARA	c.896A>G	p.N299S	Missense	7/9	-
8-42821716-G-C	HOOK3	c.880G>C	p.D294H	Missense	10/22	-
11-114112927-C-T	ZBTB16	c.1492C>T	p.R498C	Missense	5/7	-
1-158614138-C-T	SPTA1	c.4243G>A	p.E1415K	Missense	30/52	-
5-23522947-C-T	PRDM9	c.835C>T	p.R279*	Nonsense	8/11	-
4-20620574-C-T	SLIT2	c.4532C>T	p.S1511F	Missense	37/37	-
4-20570537-G-A	SLIT2	c.2998G>A	p.D1000N	Missense	29/37	-
4-20544117-G-A	SLIT2	c.2144G>A	p.G715E	Missense	21/37	-
1-27106333-G-A	ARID1A	c.5944G>A	p.V1982I	Missense	20/20	-
16-2636684-A-G	PDPK1	c.1133A>G	p.N378S	Missense	11/14	-
2-141108409-C-A	LRP1B	c.11849G>T	p.R3950M	Missense	77/91	-
2-141680639-G-A	LRP1B	c.3214C>T	p.R1072C	Missense	21/91	-
17-17122403-G-A	FLCN	c.992C>T	p.S331F	Missense	9/14	-
3-60522595-C-A	FHIT	c.101G>T	p.G34V	Missense	5/10	-
3-134851687-G-T	EPHB1	c.1093G>T	p.A365S	Missense	5/16	-
16-23646396-C-A	PALB2	c.1471G>T	p.A491S	Missense	4/13	-
2-29917727-T-C	ALK	c.941A>G	p.E314G	Missense	3/29	-
12-58145367-C-T	CDK4	c.134G>A	p.G45D	Missense	2/8	-
13-43155275-G-A	TNFSF11	c.233G>A	p.R78K	Missense	2/5	-
X-76937401-G-C	ATRX	c.3347C>G	p.S1116C	Missense	9/35	-
20-54945344-G-A	AURKA	c.1082C>T	p.S361L	Missense	9/9	-
1-158615134-C-A	SPTA1	c.4038G>T	p.Q1346H	Missense	29/52	-
11-102195343-A-G	BIRC3	c.103A>G	p.T35A	Missense	2/9	-
2-225370723-C-T	CUL3	c.1156G>A	p.E386K	Missense	8/16	-
8-139165348-C-T	FAM135B	c.1370G>A	p.R457K	Missense	13/20	-
3-30713909-G-T	TGFBR2	c.1234G>T	p.D412Y	Missense	4/7	-
2-141946137-G-A	LRP1B	c.866C>T	p.A289V	Missense	7/91	-
16-2220634-G-A	TRAF7	c.251G>A	p.R84H	Missense	5/21	-
12-133219305-C-T	POLE	c.4739G>A	p.R1580Q	Missense	37/49	-
13-32910701-G-A	BRCA2	c.2209G>A	p.A737T	Missense	11/27	-
14-95574256-C-T	DICER1	c.2611G>A	p.D871N	Missense	16/27	-
5-112178178-G-A	APC	c.6887G>A	p.S2296N	Missense	16/16	-
16-9858064-G-A	GRIN2A	c.3337C>T	p.P1113S	Missense	13/13	-
16-2115596-A-T	TSC2	c.1676A>T	p.D559V	Missense	16/42	-
5-56168656-G-A	MAP3K1	c.1510G>A	p.E504K	Missense	9/20	-
2-141299522-G-A	LRP1B	c.7213C>T	p.P2405S	Missense	44/91	-
9-8501056-G-T	PTPRD	c.1826C>A	p.P609Q	Missense	24/46	-
9-135776191-C-A	TSC1	c.2536G>T	p.E846*	Nonsense	20/23	-
5-35875633-C-T	IL7R	c.820C>T	p.P274S	Missense	7/8	-
16-3777952-G-A	CREBBP	c.7096C>T	p.R2366W	Missense	31/31	-
12-46245243-G-A	ARID2	c.3337G>A	p.G1113R	Missense	15/21	-
9-135804167-C-A	TSC1	c.93G>T	p.E31D	Missense	3/23	-
10-43600522-C-T	RET	c.748C>T	p.R250C	Missense	4/20	-
7-137613006-G-A	CREB3L2	c.209C>T	p.P70L	Missense	2/12	-
4-20525772-G-T	SLIT2	c.1410G>T	p.Q470H	Missense	14/37	-
3-189526184-G-A	TP63	c.448G>A	p.A150T	Missense	4/14	-
1-120458305-C-T	NOTCH2	c.7040G>A	p.R2347H	Missense	34/34	-
3-183273288-C-T	KLHL6	c.154G>A	p.A52T	Missense	1/7	-
5-176523730-G-GC	FGFR4	c.2147dupC	p.E717Rfs*8	Frameshift	16/18	-
3-142215345-A-G	ATR	c.5756T>C	p.M1919T	Missense	34/47	-
16-89805083-C-A	FANCA	c.4294G>T	p.V1432L	Missense	43/43	-
9-139409983-G-A	NOTCH1	c.1855C>T	p.Q619*	Nonsense	11/34	-
1-91859839-T-A	HFM1	c.305A>T	p.D102V	Missense	4/39	-
13-32911073-CA-C	BRCA2	c.2588delA	p.N863Ifs*11	Frameshift	11/27	-
16-72821959-C-CG	ZFHX3	c.10215dupC	p.G3406Rfs*25	Frameshift	10/10	-
6-146275963-C-CT	SHPRH	c.495dupA	p.E166Rfs*7	Frameshift	2/30	-
7-151900080-AT-A	KMT2C	c.4030delA	p.I1344*	Frameshift	26/59	-
16-2130219-G-A	TSC2	c.3451G>A	p.G1151S	Missense	30/42	-
5-86658451-TA-T	RASA1	c.1421delA	p.N474Tfs*9	Frameshift	10/25	-
7-81332019-C-A	HGF	c.2065G>T	p.G689C	Missense	18/18	-
3-133375611-C-T	TOPBP1	c.454G>A	p.G152S	Missense	5/28	-
17-58701021-G-T	PPM1D	c.612G>T	p.K204N	Missense	2/6	-
11-108173745-C-T	ATM	c.5485C>T	p.P1829S	Missense	36/63	-
17-7579436-GC-G	TP53	c.250delG	p.A84Pfs*39	Frameshift	4/11	-
19-1218500-A-G	STK11	c.374+1A>G	-	IntronicSNV	-	2/9
16-89833568-G-A	FANCA	c.2582C>T	p.S861F	Missense	27/43	-
16-89858890-G-C	FANCA	c.1072C>G	p.L358V	Missense	12/43	-
17-29496992-C-A	NF1	c.563C>A	p.A188E	Missense	5/58	-
8-68956825-G-A	PREX2	c.943G>A	p.A315T	Missense	8/40	-
4-187540305-G-A	FAT1	c.7435C>T	p.H2479Y	Missense	10/27	-
17-57181746-C-T	TRIM37	c.31G>A	p.E11K	Missense	2/24	-
5-80168985-A-G	MSH3	c.3181A>G	p.R1061G	Missense	23/24	-
10-8100654-G-A	GATA3	c.628G>A	p.G210R	Missense	3/6	-
1-11190765-C-T	MTOR	c.5434G>A	p.D1812N	Missense	39/58	-
1-158585172-C-T	SPTA1	c.6622G>A	p.A2208T	Missense	48/52	-
2-109382731-T-G	RANBP2	c.5736T>G	p.S1912R	Missense	20/29	-
20-31024233-T-C	ASXL1	c.3718T>C	p.C1240R	Missense	13/13	-
9-21974730-CCAG-C	CDKN2A	c.94_96delCTG	p.L32del	InFrameDeletion	1/3	-
3-89391162-G-C	EPHA3	c.1228G>C	p.D410H	Missense	5/17	-
16-89882381-C-G	FANCA	c.93G>C	p.K31N	Missense	2/43	-
11-32421568-C-T	WT1	c.1024G>A	p.D347N	Missense	6/10	-
12-133237577-C-T	POLE	c.3038G>A	p.W1013*	Nonsense	25/49	-
2-234677040-C-T	UGT1A5	c.1262C>T	p.S421F	Missense	4/5	-
4-187630278-C-A	FAT1	c.704G>T	p.S235I	Missense	2/27	-
2-212248684-G-A	ERBB4	c.3583C>T	p.P1195S	Missense	28/28	-
16-11000403-G-A	CIITA	c.1054G>A	p.E352K	Missense	11/20	-
X-70346843-G-T	MED12	c.2710G>T	p.E904*	Nonsense	20/45	-
2-29498343-C-T	ALK	c.1837G>A	p.A613T	Missense	10/29	-
3-52443894-T-C	BAP1	c.1A>G	p.M1?	Missense	1/17	-
5-112179557-A-G	APC	c.8266A>G	p.I2756V	Missense	16/16	-
22-30077482-G-C	NF2	c.1629G>C	p.K543N	Missense	15/16	-
4-55131140-G-T	PDGFRA	c.683G>T	p.G228V	Missense	5/23	-
3-52623229-G-A	PBRM1	c.2822C>T	p.S941L	Missense	19/30	-
16-89842176-C-T	FANCA	c.1874G>A	p.C625Y	Missense	21/43	-
1-156838381-G-A	NTRK1	c.659G>A	p.R220Q	Missense	6/17	-
3-47161801-G-A	SETD2	c.4325C>T	p.S1442L	Missense	3/21	-
19-17945780-C-T	JAK3	c.2080G>A	p.E694K	Missense	16/24	-
15-88727457-G-T	NTRK3	c.322C>A	p.L108M	Missense	4/20	-
13-29041075-T-A	FLT1	c.353A>T	p.K118M	Missense	3/30	-
9-87317280-G-T	NTRK2	c.305G>T	p.G102V	Missense	4/19	-
5-156665173-G-T	ITK	c.823G>T	p.V275L	Missense	9/17	-
15-88679802-C-A	NTRK3	c.661G>T	p.V221L	Missense	8/20	-
11-108121562-G-C	ATM	c.1370G>C	p.R457P	Missense	10/63	-
9-87338624-G-C	NTRK2	c.720G>C	p.M240I	Missense	7/19	-
5-148886653-C-A	CSNK1A1	c.794G>T	p.G265V	Missense	8/10	-
19-4409685-G-A	CHAF1A	c.889G>A	p.E297K	Missense	3/15	-
3-130962292-G-A	NEK11	c.1573G>A	p.E525K	Missense	16/18	-
10-83635422-G-T	NRG3	c.326G>T	p.G109V	Missense	1/9	-
13-29002009-G-T	FLT1	c.1156C>A	p.R386S	Missense	9/30	-
15-93482926-C-T	CHD2	c.670C>T	p.R224*	Nonsense	7/39	-
X-47028875-C-G	RBM10	c.179C>G	p.S60*	Nonsense	3/24	-
19-11107056-G-T	SMARCA4	c.1761G>T	p.K587N	Missense	10/35	-
3-126708409-G-T	PLXNA1	c.973G>T	p.A325S	Missense	2/32	-
X-70360588-GAGC-G	MED12	c.6165_6167delGCA	p.Q2076del	InFrameDeletion	42/45	-
5-176638711-A-G	NSD1	c.3311A>G	p.H1104R	Missense	5/23	-
3-89391019-T-C	EPHA3	c.1085T>C	p.I362T	Missense	5/17	-
X-123159736-G-T	STAG2	c.91G>T	p.E31*	Nonsense	4/35	-
22-22221654-G-T	MAPK1	c.77C>A	p.T26N	Missense	1/9	-
1-158656285-G-A	SPTA1	c.23C>T	p.T8I	Missense	1/52	-
2-128028923-C-A	ERCC3	c.1934G>T	p.R645L	Missense	12/15	-
13-32911085-G-A	BRCA2	c.2593G>A	p.E865K	Missense	11/27	-
15-93528878-G-A	CHD2	c.3388G>A	p.G1130R	Missense	26/39	-
5-35873670-C-T	IL7R	c.626C>T	p.P209L	Missense	5/8	-
4-187518002-G-A	FAT1	c.12692C>T	p.P4231L	Missense	25/27	-
16-1544301-GA-AG	TELO2	c.19_20delGAinsAG	p.E7R	Missense	2/21	-
8-68864748-G-A	PREX2	c.119G>A	p.G40D	Missense	1/40	-
5-176636707-G-A	NSD1	c.1307G>A	p.G436E	Missense	5/23	-
11-108225548-A-G	ATM	c.8797A>G	p.K2933E	Missense	61/63	-
16-23649230-G-A	PALB2	c.152C>T	p.T51I	Missense	3/13	-
16-23641779-G-A	PALB2	c.1696C>T	p.R566C	Missense	5/13	-
16-23640578-G-A	PALB2	c.2533C>T	p.P845S	Missense	6/13	-
1-243736269-C-T	AKT3	c.778G>A	p.D260N	Missense	9/14	-
4-106156810-C-T	TET2	c.1711C>T	p.R571C	Missense	3/11	-
2-141459350-T-A	LRP1B	c.6367A>T	p.R2123*	Nonsense	40/91	-
2-233198649-C-T	DIS3L2	c.2110C>T	p.R704C	Missense	17/21	-
9-35078250-G-A	FANCG	c.398C>T	p.P133L	Missense	4/14	-
2-141128831-C-T	LRP1B	c.10792G>A	p.E3598K	Missense	70/91	-
3-89259629-C-T	EPHA3	c.773C>T	p.S258F	Missense	3/17	-
6-93967900-C-T	EPHA7	c.2027G>A	p.R676K	Missense	11/17	-
X-123185040-A-G	STAG2	c.1087A>G	p.K363E	Missense	12/35	-
3-181430799-G-A	SOX2	c.651G>A	p.M217I	Missense	1/1	-
4-106156003-G-C	TET2	c.904G>C	p.D302H	Missense	3/11	-
1-243736331-C-G	AKT3	c.716G>C	p.R239T	Missense	9/14	-
7-41739896-G-A	INHBA	c.77C>T	p.S26F	Missense	2/3	-
3-47125800-T-A	SETD2	c.5470A>T	p.I1824F	Missense	12/21	-
12-115114223-C-T	TBX3	c.934G>A	p.E312K	Missense	5/7	-
7-6441589-G-A	RAC1	c.379G>A	p.E127K	Missense	5/6	-
12-46233237-A-G	ARID2	c.1456A>G	p.I486V	Missense	11/21	-
17-37627724-C-T	CDK12	c.1639C>T	p.Q547*	Nonsense	2/14	-
X-53250092-G-A	KDM5C	c.157C>T	p.Q53*	Nonsense	2/26	-
1-11316222-T-C	MTOR	c.532A>G	p.S178G	Missense	5/58	-
9-135782182-A-T	TSC1	c.1374T>A	p.D458E	Missense	14/23	-
19-11145764-G-A	SMARCA4	c.4126G>A	p.E1376K	Missense	29/35	-
19-11144051-A-T	SMARCA4	c.3632A>T	p.E1211V	Missense	26/35	-
19-11098521-C-T	SMARCA4	c.1039C>T	p.Q347*	Nonsense	6/35	-
19-11130271-C-T	SMARCA4	c.2510C>T	p.S837F	Missense	18/35	-
19-11105534-A-T	SMARCA4	c.1450A>T	p.K484*	Nonsense	9/35	-
9-133760305-G-T	ABL1	c.2628G>T	p.R876S	Missense	11/11	-
19-11105633-A-G	SMARCA4	c.1549A>G	p.K517E	Missense	9/35	-
19-11123674-G-T	SMARCA4	c.2324G>T	p.G775V	Missense	16/35	-
11-102195365-G-T	BIRC3	c.125G>T	p.G42V	Missense	2/9	-
19-11105546-G-T	SMARCA4	c.1462G>T	p.E488*	Nonsense	9/35	-
19-11129646-T-A	SMARCA4	c.2452T>A	p.W818R	Missense	17/35	-
19-11113802-G-A	SMARCA4	c.1910G>A	p.G637E	Missense	12/35	-
11-118343855-G-A	KMT2A	c.1981G>A	p.V661I	Missense	3/36	-
1-27106249-A-G	ARID1A	c.5860A>G	p.I1954V	Missense	20/20	-
4-55604658-C-T	KIT	c.2866C>T	p.R956W	Missense	21/21	-
19-855794-C-T	ELANE	c.597C>T	p.F199=	Synonymous	4/5	-
14-36986793-G-A	NKX2-1	c.896C>T	p.P299L	Missense	3/3	-
1-226253448-G-C	H3-3A	c.220G>C	p.E74Q	Missense	3/4	-
X-47035902-TC-T	RBM10	c.583delC	p.L195Sfs*71	Frameshift	7/24	-
15-88423587-C-T	NTRK3	c.2248G>A	p.E750K	Missense	19/20	-
15-38614537-T-TA	SPRED1	c.304dupA	p.T102Nfs*7	Frameshift	3/7	-
2-29917835-G-A	ALK	c.833C>T	p.P278L	Missense	3/29	-
7-55242466-GAATTAAGAGAAGCAACATCTC-CTCT	EGFR	c.2236_2257delinsCTCT	p.E746_P753delinsLS	MultiAAMissense	19/28	-
14-45644349-A-G	FANCM	c.2392A>G	p.R798G	Missense	14/23	-
16-10031815-C-A	GRIN2A	c.1007+1G>T	-	IntronicSNV	-	3/12
2-141773372-G-T	LRP1B	c.2083C>A	p.L695M	Missense	13/91	-
9-98242731-A-G	PTCH1	c.886T>C	p.C296R	Missense	6/24	-
16-23646541-A-C	PALB2	c.1326T>G	p.N442K	Missense	4/13	-
16-23646311-G-T	PALB2	c.1556C>A	p.A519D	Missense	4/13	-
2-178098988-C-G	NFE2L2	c.57G>C	p.L19F	Missense	2/5	-
12-56492590-G-C	ERBB3	c.2740G>C	p.G914R	Missense	23/28	-
13-48953755-A-T	RB1	c.1358A>T	p.Y453F	Missense	14/27	-
1-27023042-A-G	ARID1A	c.148A>G	p.M50V	Missense	1/20	-
11-108155009-G-A	ATM	c.3802G>A	p.V1268M	Missense	26/63	-
16-89877455-G-A	FANCA	c.308C>T	p.S103L	Missense	4/43	-
9-80430646-A-C	GNAQ	c.362T>G	p.V121G	Missense	3/7	-
22-41564837-G-A	EP300	c.4138G>A	p.E1380K	Missense	25/31	-
12-112910782-G-A	PTPN11	c.791G>A	p.S264N	Missense	7/16	-
5-180051032-G-T	FLT4	c.1451C>A	p.P484Q	Missense	11/30	-
12-49425839-G-A	KMT2D	c.12649C>T	p.Q4217*	Nonsense	40/55	-
12-46230734-G-T	ARID2	c.983G>T	p.R328M	Missense	8/21	-
5-11082871-C-G	CTNND2	c.2725G>C	p.V909L	Missense	16/22	-
3-30713601-C-T	TGFBR2	c.926C>T	p.T309M	Missense	4/7	-
6-162622243-C-T	PRKN	c.454G>A	p.G152S	Missense	4/12	-
19-10600416-C-A	KEAP1	c.1439G>T	p.G480V	Missense	4/6	-
5-112177043-A-G	APC	c.5752A>G	p.I1918V	Missense	16/16	-
16-23649267-G-A	PALB2	c.115C>T	p.Q39*	Nonsense	3/13	-
16-23647206-C-T	PALB2	c.661G>A	p.V221I	Missense	4/13	-
11-108139279-G-T	ATM	c.2781G>T	p.L927F	Missense	18/63	-
22-42525781-A-G	CYP2D6	c.311T>C	p.V104A	Missense	2/9	-
13-43148565-CT-C	TNFSF11	c.126delT	p.A43Pfs*49	Frameshift	1/5	-
18-61324574-T-C	SERPINB3	c.542A>G	p.Y181C	Missense	6/8	-
X-76854937-C-T	ATRX	c.5899G>A	p.E1967K	Missense	25/35	-
4-55597532-G-T	KIT	c.2180G>T	p.G727V	Missense	15/21	-
12-56481680-C-G	ERBB3	c.715C>G	p.Q239E	Missense	6/28	-
9-135798765-G-A	TSC1	c.478C>T	p.R160C	Missense	6/23	-
12-49416132-C-T	KMT2D	c.16343G>A	p.R5448Q	Missense	53/55	-
1-27100175-A-AC	ARID1A	c.3977dupC	p.Q1327Afs*11	Frameshift	16/20	-
17-59885858-C-G	BRIP1	c.888G>C	p.E296D	Missense	7/20	-
16-23641130-G-T	PALB2	c.2345C>A	p.P782Q	Missense	5/13	-
X-76952107-C-T	ATRX	c.328G>A	p.E110K	Missense	5/35	-
17-37872647-G-A	ERBB2	c.1607G>A	p.R536Q	Missense	13/27	-
17-38564779-T-A	TOP2A	c.1307A>T	p.K436M	Missense	11/35	-
2-29754824-C-T	ALK	c.1111G>A	p.A371T	Missense	4/29	-
16-23641376-G-A	PALB2	c.2099C>T	p.S700L	Missense	5/13	-
X-53240802-C-A	KDM5C	c.1278G>T	p.W426C	Missense	10/26	-
4-55594200-G-A	KIT	c.1903G>A	p.E635K	Missense	13/21	-
3-189584569-C-T	TP63	c.865C>T	p.P289S	Missense	6/14	-
4-55602730-G-T	KIT	c.2551G>T	p.D851Y	Missense	18/21	-
19-10610307-G-A	KEAP1	c.403C>T	p.R135C	Missense	2/6	-
2-47639568-GGA-AGC	MSH2	c.661_663delGGAinsAGC	p.G221S	Missense	4/16	-
3-30729955-G-C	TGFBR2	c.1476G>C	p.L492F	Missense	6/7	-
2-173451087-C-T	PDK1	c.1027C>T	p.R343C	Missense	9/11	-
3-89445020-G-A	EPHA3	c.1340G>A	p.R447Q	Missense	6/17	-
2-47639632-A-G	MSH2	c.725A>G	p.N242S	Missense	4/16	-
5-176522701-A-T	FGFR4	c.1798A>T	p.M600L	Missense	13/18	-
12-49426624-A-T	KMT2D	c.11864T>A	p.L3955Q	Missense	40/55	-
X-47030585-T-G	RBM10	c.201+1688T>G	p.D120E	UnclassifiedSNV	4/24	-
3-142188222-G-A	ATR	c.6509C>T	p.A2170V	Missense	38/47	-
4-187630131-C-T	FAT1	c.851G>A	p.G284D	Missense	2/27	-
9-98220389-C-T	PTCH1	c.3074G>A	p.R1025H	Missense	18/24	-
19-11134277-G-T	SMARCA4	c.2943G>T	p.K981N	Missense	20/35	-
13-32914636-T-G	BRCA2	c.6144T>G	p.N2048K	Missense	11/27	-
19-52716227-C-T	PPP2R1A	c.671C>T	p.A224V	Missense	6/15	-
3-52662944-T-C	PBRM1	c.1409A>G	p.Y470C	Missense	13/30	-
19-45867569-T-C	ERCC2	c.739A>G	p.M247V	Missense	9/23	-
9-98231215-C-T	PTCH1	c.2068G>A	p.V690I	Missense	14/24	-
13-32912895-C-G	BRCA2	c.4403C>G	p.S1468C	Missense	11/27	-
5-56111750-C-T	MAP3K1	c.350C>T	p.A117V	Missense	1/20	-
13-32914788-G-C	BRCA2	c.6296G>C	p.R2099T	Missense	11/27	-
1-16202899-C-T	SPEN	c.607C>T	p.P203S	Missense	3/15	-
X-47039294-A-T	RBM10	c.917A>T	p.N306I	Missense	10/24	-
2-141607869-G-A	LRP1B	c.4741C>T	p.R1581C	Missense	29/91	-
3-47162207-C-T	SETD2	c.3919G>A	p.D1307N	Missense	3/21	-
X-76938775-C-T	ATRX	c.1973G>A	p.R658H	Missense	9/35	-
16-23619310-A-T	PALB2	c.3225T>A	p.S1075R	Missense	12/13	-
9-135798863-A-G	TSC1	c.380T>C	p.V127A	Missense	6/23	-
17-63554674-G-A	AXIN2	c.65C>T	p.P22L	Missense	2/11	-
X-123182892-A-T	STAG2	c.857A>T	p.N286I	Missense	10/35	-
2-141359103-C-T	LRP1B	c.6905G>A	p.R2302Q	Missense	42/91	-
22-41513599-G-A	EP300	c.503G>A	p.G168E	Missense	2/31	-
4-187509973-C-A	FAT1	c.13540G>T	p.E4514*	Nonsense	27/27	-
16-68845705-C-A	CDH1	c.951C>A	p.F317L	Missense	7/16	-
X-47039333-C-T	RBM10	c.956C>T	p.A319V	Missense	10/24	-
4-187629567-A-C	FAT1	c.1415T>G	p.F472C	Missense	2/27	-
1-156843544-G-C	NTRK1	c.970G>C	p.E324Q	Missense	8/17	-
5-176637034-C-T	NSD1	c.1634C>T	p.T545M	Missense	5/23	-
X-47041654-A-T	RBM10	c.1879A>T	p.K627*	Nonsense	17/24	-
5-112175255-G-A	APC	c.3964G>A	p.E1322K	Missense	16/16	-
2-215674197-C-A	BARD1	c.97G>T	p.A33S	Missense	1/11	-
11-32450088-G-T	WT1	c.724C>A	p.H247N	Missense	2/10	-
19-10600361-TC-AT	KEAP1	c.1493_1494delGAinsAT	p.R498H	Missense	4/6	-
11-108213995-G-C	ATM	c.8315G>C	p.G2772A	Missense	57/63	-
15-40462838-C-T	BUB1B	c.340C>T	p.R114*	Nonsense	4/23	-
16-3808911-C-G	CREBBP	c.3313G>C	p.D1105H	Missense	17/31	-
12-92539225-C-A	BTG1	c.87G>T	p.K29N	Missense	1/2	-
5-225584-G-A	SDHA	c.363G>A	p.W121*	Nonsense	4/15	-
12-49436527-G-A	KMT2D	c.5779C>T	p.Q1927*	Nonsense	27/55	-
9-135780999-C-A	TSC1	c.1966G>T	p.G656*	Nonsense	15/23	-
9-21971147-TG-T	CDKN2A	c.210delC	p.N71Tfs*75	Frameshift	2/3	-
12-4385236-C-G	CCND2	c.261C>G	p.F87L	Missense	2/5	-
7-128851524-G-C	SMO	c.1849G>C	p.A617P	Missense	11/12	-
12-49440414-T-A	KMT2D	c.4396A>T	p.K1466*	Nonsense	16/55	-
5-131893129-A-G	RAD50	c.113A>G	p.N38S	Missense	1/25	-
16-3779074-C-T	CREBBP	c.5974G>A	p.G1992R	Missense	31/31	-
9-98215773-C-T	PTCH1	c.3436G>A	p.D1146N	Missense	20/24	-
16-23637568-G-A	PALB2	c.2737C>T	p.H913Y	Missense	7/13	-
7-128829135-C-T	SMO	c.143C>T	p.A48V	Missense	1/12	-
17-70120028-C-G	SOX9	c.1030C>G	p.P344A	Missense	3/3	-
16-23625394-T-A	PALB2	c.3132A>T	p.Q1044H	Missense	11/13	-
3-52437816-C-T	BAP1	c.1345G>A	p.A449T	Missense	13/17	-
1-120468089-C-A	NOTCH2	c.4350G>T	p.W1450C	Missense	25/34	-
2-212615399-C-T	ERBB4	c.587G>A	p.R196H	Missense	5/28	-
2-215645733-G-A	BARD1	c.865C>T	p.P289S	Missense	4/11	-
1-59248123-GGCT-G	JUN	c.617_619delAGC	p.Q206del	InFrameDeletion	1/1	-
16-2134293-T-A	TSC2	c.4070T>A	p.I1357N	Missense	34/42	-
7-152357792-C-T	XRCC2	c.115G>A	p.V39M	Missense	2/3	-
16-23646342-C-T	PALB2	c.1525G>A	p.G509S	Missense	4/13	-
16-2110728-C-T	TSC2	c.1033C>T	p.L345F	Missense	11/42	-
22-41573449-C-T	EP300	c.5734C>T	p.Q1912*	Nonsense	31/31	-
16-23632700-C-T	PALB2	c.3096G>A	p.M1032I	Missense	10/13	-
1-45797929-G-A	MUTYH	c.758C>T	p.A253V	Missense	10/16	-
6-161781212-G-T	PRKN	c.1193C>A	p.A398D	Missense	11/12	-
8-68950505-G-T	PREX2	c.817G>T	p.V273L	Missense	7/40	-
17-29585494-G-T	NF1	c.4306G>T	p.E1436*	Nonsense	32/58	-
7-92462461-G-C	CDK6	c.177C>G	p.I59M	Missense	2/8	-
10-104375077-G-A	SUFU	c.1075G>A	p.E359K	Missense	9/12	-
15-88420308-C-A	NTRK3	c.2378G>T	p.R793L	Missense	20/20	-
7-41729978-C-T	INHBA	c.551G>A	p.G184D	Missense	3/3	-
2-141201990-G-C	LRP1B	c.10203C>G	p.F3401L	Missense	65/91	-
4-143045777-C-A	INPP4B	c.1857G>T	p.M619I	Missense	19/26	-
1-226553675-A-T	PARP1	c.2485T>A	p.Y829N	Missense	18/23	-
2-48032846-G-C	MSH6	c.3646G>C	p.G1216R	Missense	7/10	-
12-49427072-G-A	KMT2D	c.11416C>T	p.Q3806*	Nonsense	40/55	-
1-27023783-C-T	ARID1A	c.889C>T	p.Q297*	Nonsense	1/20	-
3-52441192-T-G	BAP1	c.578A>C	p.H193P	Missense	7/17	-
16-23647236-C-T	PALB2	c.631G>A	p.E211K	Missense	4/13	-
13-32913339-T-A	BRCA2	c.4847T>A	p.L1616*	Nonsense	11/27	-
13-32910896-A-G	BRCA2	c.2404A>G	p.N802D	Missense	11/27	-
13-32911148-A-G	BRCA2	c.2656A>G	p.N886D	Missense	11/27	-
17-41244808-C-G	BRCA1	c.2740G>C	p.E914Q	Missense	10/23	-
17-41244214-C-G	BRCA1	c.3334G>C	p.E1112Q	Missense	10/23	-
14-45633697-C-T	FANCM	c.1717C>T	p.R573*	Nonsense	10/23	-
17-41244826-C-G	BRCA1	c.2722G>C	p.E908Q	Missense	10/23	-
20-36031747-A-T	SRC	c.1576A>T	p.T526S	Missense	14/14	-
13-32914806-T-C	BRCA2	c.6314T>C	p.I2105T	Missense	11/27	-
13-32914645-T-G	BRCA2	c.6153T>G	p.N2051K	Missense	11/27	-
7-2958174-C-A	CARD11	c.2558G>T	p.G853V	Missense	19/25	-
16-72831854-G-C	ZFHX3	c.4727C>G	p.A1576G	Missense	9/10	-
17-41246379-T-A	BRCA1	c.1169A>T	p.D390V	Missense	10/23	-
3-142177832-C-T	ATR	c.7471G>A	p.V2491I	Missense	44/47	-
2-141707966-C-T	LRP1B	c.2974G>A	p.D992N	Missense	20/91	-
1-98165090-A-G	DPYD	c.497T>C	p.M166T	Missense	6/23	-
2-141115603-C-A	LRP1B	c.11340G>T	p.Q3780H	Missense	74/91	-
17-17118562-C-T	FLCN	c.1369G>A	p.D457N	Missense	12/14	-
2-25459852-C-G	DNMT3A	c.2431G>C	p.D811H	Missense	21/23	-
1-27100204-C-T	ARID1A	c.4000C>T	p.Q1334*	Nonsense	16/20	-
16-23647430-C-T	PALB2	c.437G>A	p.R146K	Missense	4/13	-
5-38982093-G-A	RICTOR	c.629C>T	p.T210I	Missense	8/38	-
13-32903606-G-T	BRCA2	c.658G>T	p.V220L	Missense	8/27	-
2-25463233-G-C	DNMT3A	c.2260C>G	p.L754V	Missense	19/23	-
5-240575-G-A	SDHA	c.1535G>A	p.R512Q	Missense	11/15	-
19-1221212-C-G	STK11	c.735C>G	p.L245=	Synonymous	6/10	-
6-116288856-C-A	FRK	c.657G>T	p.L219F	Missense	4/8	-
11-44255777-G-A	EXT2	c.1919G>A	p.G640E	Missense	12/14	-
1-46743589-C-G	RAD54L	c.1970C>G	p.S657C	Missense	17/18	-
15-42040903-C-T	MGA	c.5281C>T	p.R1761*	Nonsense	16/24	-
19-11144125-C-A	SMARCA4	c.3706C>A	p.Q1236K	Missense	26/35	-
16-23646607-C-A	PALB2	c.1260G>T	p.Q420H	Missense	4/13	-
16-68845703-T-C	CDH1	c.949T>C	p.F317L	Missense	7/16	-
11-32417814-C-T	WT1	c.1238G>A	p.R418K	Missense	7/10	-
16-23614950-T-C	PALB2	c.3391A>G	p.I1131V	Missense	13/13	-
X-47422634-C-T	ARAF	c.106C>T	p.R36W	Missense	3/16	-
16-23652445-C-G	PALB2	c.34G>C	p.E12Q	Missense	1/13	-
19-10600004-G-GC	KEAP1	c.1571_1571dupG	p.Y525Lfs*2	Frameshift	5/6	-
11-118307261-C-G	KMT2A	c.34C>G	p.R12G	Missense	1/36	-
9-8517962-T-A	PTPRD	c.1429A>T	p.T477S	Missense	21/46	-
X-47040801-G-T	RBM10	c.1435+1G>T	-	IntronicSNV	-	13/23
X-47039638-C-T	RBM10	c.1090C>T	p.Q364*	Nonsense	11/24	-
17-8045175-G-T	PER1	c.3548C>A	p.A1183D	Missense	22/23	-
2-42488301-G-A	EML4	c.379G>A	p.E127K	Missense	4/23	-
12-6705221-C-T	CHD4	c.1975G>A	p.V659M	Missense	13/40	-
5-170827852-G-T	NPM1	c.592G>T	p.D198Y	Missense	8/11	-
7-41729603-C-T	INHBA	c.926G>A	p.R309Q	Missense	3/3	-
6-169629723-C-A	THBS2	c.2203G>T	p.G735W	Missense	14/22	-
1-120480014-G-A	NOTCH2	c.3413C>T	p.P1138L	Missense	21/34	-
12-46245849-G-C	ARID2	c.3943G>C	p.E1315Q	Missense	15/21	-
8-139278044-C-T	FAM135B	c.199G>A	p.V67M	Missense	4/20	-
1-193111138-T-C	CDC73	c.671T>C	p.I224T	Missense	7/17	-
7-66460388-G-A	SBDS	c.17C>T	p.P6L	Missense	1/5	-
1-76288153-G-A	MSH4	c.1049G>A	p.R350Q	Missense	7/20	-
1-76365319-G-C	MSH4	c.2547G>C	p.E849D	Missense	19/20	-
5-11082936-G-C	CTNND2	c.2660C>G	p.A887G	Missense	16/22	-
22-29091722-C-T	CHEK2	c.1235G>A	p.S412N	Missense	11/15	-
8-41791504-C-A	KAT6A	c.4234G>T	p.E1412*	Nonsense	17/17	-
15-88726665-G-T	NTRK3	c.379C>A	p.P127T	Missense	5/20	-
4-187627830-G-T	FAT1	c.3152C>A	p.S1051*	Nonsense	2/27	-
2-141272254-C-A	LRP1B	c.8237G>T	p.G2746V	Missense	51/91	-
7-142649673-C-A	KEL	c.1126G>T	p.A376S	Missense	10/19	-
16-2103365-A-G	TSC2	c.248A>G	p.K83R	Missense	4/42	-
7-142640585-G-T	KEL	c.1691C>A	p.P564H	Missense	15/19	-
10-84745064-C-G	NRG3	c.1794C>G	p.I598M	Missense	9/9	-
7-41729875-C-A	INHBA	c.654G>T	p.W218C	Missense	3/3	-
2-109365532-G-A	RANBP2	c.1220G>A	p.G407E	Missense	9/29	-
15-99482568-G-T	IGF1R	c.3436G>T	p.D1146Y	Missense	18/21	-
5-112179728-A-G	APC	c.8437A>G	p.T2813A	Missense	16/16	-
13-28609743-C-A	FLT3	c.1486G>T	p.V496L	Missense	12/24	-
17-7577521-TG-T	TP53	c.759delC	p.I254Sfs*91	Frameshift	7/11	-
9-35075597-C-T	FANCG	c.1298G>A	p.R433Q	Missense	10/14	-
16-23634440-C-T	PALB2	c.2846G>A	p.C949Y	Missense	9/13	-
9-139417485-C-A	NOTCH1	c.559G>T	p.G187W	Missense	4/34	-
2-141819745-G-A	LRP1B	c.1111C>T	p.Q371*	Nonsense	8/91	-
17-37673794-G-T	CDK12	c.2948G>T	p.R983L	Missense	10/14	-
9-139413937-C-T	NOTCH1	c.823G>A	p.G275S	Missense	5/34	-
7-151945021-C-T	KMT2C	c.2498G>A	p.R833K	Missense	14/59	-
3-142218534-G-A	ATR	c.5315C>T	p.T1772M	Missense	31/47	-
4-1374719-G-A	UVSSA	c.1804G>A	p.D602N	Missense	12/14	-
3-89521616-C-T	EPHA3	c.2693C>T	p.P898L	Missense	16/17	-
X-63410555-C-T	AMER1	c.2612G>A	p.R871Q	Missense	2/2	-
X-47030553-G-A	RBM10	c.328G>A	p.E110K	Missense	4/24	-
16-23641163-C-T	PALB2	c.2312G>A	p.S771N	Missense	5/13	-
19-10461554-C-T	TYK2	c.3520G>A	p.E1174K	Missense	25/25	-
7-142640065-C-T	KEL	c.1838G>A	p.R613H	Missense	17/19	-
4-20512726-G-A	SLIT2	c.1024G>A	p.D342N	Missense	11/37	-
4-20255548-G-T	SLIT2	c.110G>T	p.S37I	Missense	1/37	-
12-56361648-G-A	CDK2	c.124G>A	p.E42K	Missense	2/7	-
5-112174304-G-A	APC	c.3013G>A	p.A1005T	Missense	16/16	-
4-20535339-G-T	SLIT2	c.1832+1G>T	-	IntronicSNV	-	18/36
1-193181231-G-A	CDC73	c.1066+1G>A	-	IntronicSNV	-	12/16
17-29550586-G-T	NF1	c.1845+1G>T	-	IntronicSNV	-	16/57
X-153995337-G-A	DKC1	c.513+1G>A	-	IntronicSNV	-	6/14
15-91312816-GTGTAAGTT-G	BLM	c.2555_2555+7delTGTAAGTT	-	SpliceDonorDeletion	12/22	12/21
10-115608738-C-A	DCLRE1A	c.2125+1G>T	-	IntronicSNV	-	2/8
2-141359013-TCTTA-T	LRP1B	c.6989+2_6989+5delTAAG	-	IntronicDeletion	42/91	42/90
X-47038564-T-C	RBM10	c.724+2T>C	-	IntronicSNV	-	8/23
19-10602662-C-T	KEAP1	c.916G>A	p.E306K	Missense	3/6	-
13-25021149-TCTTACC-T	PARP4	c.3285_3285+5delGGTAAG	-	SpliceDonorDeletion	26/34	26/33
12-65460420-C-T	WIF1	c.730+1G>A	-	IntronicSNV	-	6/9
16-2135005-AGCCAATCCTGCTGCCCAATGAGGTAGGCGTG-A	TSC2	c.4551_4569+12del31	-	SpliceDonorDeletion	35/42	35/41
X-47040801-G-A	RBM10	c.1435+1G>A	-	IntronicSNV	-	13/23
3-133368623-C-A	TOPBP1	c.1253+1G>T	-	IntronicSNV	-	9/27
22-30032840-TGGCCTGGCTCAAAATGGACAAGAA-T	NF2	c.218_240+1del24	-	SpliceDonorDeletion	2/16	2/15
17-30320353-G-A	SUZ12	c.1293+1G>A	-	IntronicSNV	-	11/15
17-57970687-G-C	RPS6KB1	c.141+1G>C	-	IntronicSNV	-	1/14
X-47041442-G-T	RBM10	c.1785+1G>T	-	IntronicSNV	-	16/23
X-76855200-C-T	ATRX	c.5786+1G>A	-	IntronicSNV	-	24/34
X-70341288-G-C	MED12	c.846+1G>C	-	IntronicSNV	-	6/44
3-52702513-C-T	PBRM1	c.384+1G>A	-	IntronicSNV	-	4/29
2-225371574-C-T	CUL3	c.1029+1G>A	-	IntronicSNV	-	7/15
17-29554302-ACACTGAGGTATG-A	NF1	c.2320_2325+6del12	-	SpliceDonorDeletion	19/58	19/57
9-135776974-A-G	TSC1	c.2502+2T>C	-	IntronicSNV	-	19/22
13-48954214-ATTTTAGGTAAATTTTTTACTTTTAGTAAAAAAT-A	RB1	c.1420_1421+31del33	-	SpliceDonorDeletion	15/27	15/26
11-94212839-C-T	MRE11	c.402+1G>A	-	IntronicSNV	-	5/19
4-110880578-CGGAAGTACTGTGAAGGTAATGACT-C	EGF	c.1066+7_1066+30del24	-	SpliceDonorDeletion	-	6/23
14-50929382-C-A	MAP4K5	c.936+1G>T	-	IntronicSNV	-	13/32
3-10183644-C-G	VHL	c.113C>G	p.S38C	Missense	1/3	-
16-3779514-T-A	CREBBP	c.5534A>T	p.N1845I	Missense	31/31	-
9-407021-G-T	DOCK8	c.3482G>T	p.G1161V	Missense	28/48	-
1-120459158-C-A	NOTCH2	c.6187G>T	p.D2063Y	Missense	34/34	-
8-30938661-G-T	WRN	c.1118G>T	p.G373V	Missense	9/35	-
7-77885889-A-G	MAGI2	c.1418T>C	p.I473T	Missense	10/22	-
16-23641061-A-T	PALB2	c.2414T>A	p.V805D	Missense	5/13	-
8-37699436-G-A	ADGRA2	c.3580G>A	p.E1194K	Missense	19/19	-
8-139149480-C-A	FAM135B	c.3925G>T	p.V1309L	Missense	19/20	-
5-176517475-G-T	FGFR4	c.176G>T	p.R59L	Missense	3/18	-
13-28578228-C-A	FLT3	c.2943G>T	p.L981F	Missense	24/24	-
12-121426800-C-T	HNF1A	c.491C>T	p.T164I	Missense	2/10	-
1-65301896-T-C	JAK1	c.3143A>G	p.Y1048C	Missense	23/25	-
3-181430462-A-T	SOX2	c.314A>T	p.H105L	Missense	1/1	-
9-27192496-A-T	TEK	c.1499A>T	p.E500V	Missense	11/23	-
1-158615154-C-G	SPTA1	c.4018G>C	p.A1340P	Missense	29/52	-
1-27106807-C-A	ARID1A	c.6418C>A	p.P2140T	Missense	20/20	-
2-225422564-C-A	CUL3	c.76G>T	p.D26Y	Missense	2/16	-
8-139163826-A-T	FAM135B	c.2892T>A	p.D964E	Missense	13/20	-
11-69457974-GCATCTACACCGACAACTC-G	CCND1	c.379_396del18	p.Y127_I132del	InFrameDeletion	2/5	-
2-141201898-C-G	LRP1B	c.10294+1G>C	-	IntronicSNV	-	65/90
13-48947630-T-A	RB1	c.1215+2T>A	-	IntronicSNV	-	12/26
16-9857697-T-A	GRIN2A	c.3704A>T	p.K1235M	Missense	13/13	-
X-70342101-G-C	MED12	c.1153G>C	p.D385H	Missense	8/45	-
3-130873910-C-G	NEK11	c.907C>G	p.L303V	Missense	10/18	-
16-23646335-C-G	PALB2	c.1532G>C	p.R511T	Missense	4/13	-
5-38991087-T-C	RICTOR	c.547A>G	p.M183V	Missense	7/38	-
1-179077208-G-C	ABL2	c.3194C>G	p.T1065S	Missense	12/12	-
11-108201002-G-C	ATM	c.7369G>C	p.E2457Q	Missense	50/63	-
11-119155906-C-G	CBL	c.1571C>G	p.S524C	Missense	11/16	-
1-16475355-G-A	EPHA2	c.341C>T	p.S114F	Missense	3/17	-
8-139163608-C-T	FAM135B	c.3110G>A	p.C1037Y	Missense	13/20	-
8-38271713-C-T	FGFR1	c.2143G>A	p.E715K	Missense	16/18	-
5-176518781-C-G	FGFR4	c.699C>G	p.I233M	Missense	6/18	-
13-29008044-A-T	FLT1	c.725T>A	p.L242*	Nonsense	6/30	-
5-180056313-T-A	FLT4	c.931A>T	p.K311*	Nonsense	7/30	-
X-48651646-G-A	GATA1	c.812G>A	p.R271K	Missense	5/6	-
12-57858996-G-A	GLI1	c.492G>A	p.M164I	Missense	5/12	-
7-42006199-C-T	GLI3	c.2472G>A	p.M824I	Missense	15/15	-
7-86469220-G-C	GRM3	c.2390G>C	p.R797T	Missense	4/6	-
11-118352586-G-T	KMT2A	c.3791G>T	p.R1264L	Missense	7/36	-
12-49418652-G-C	KMT2D	c.15862C>G	p.L5288V	Missense	50/55	-
2-141215164-A-T	LRP1B	c.9682T>A	p.Y3228N	Missense	61/91	-
2-141004663-A-C	LRP1B	c.13316T>G	p.I4439S	Missense	87/91	-
17-29664894-C-G	NF1	c.6700C>G	p.Q2234E	Missense	44/58	-
1-120478115-G-C	NOTCH2	c.3635C>G	p.S1212C	Missense	22/34	-
16-23635385-C-G	PALB2	c.2779G>C	p.D927H	Missense	8/13	-
19-18278007-G-A	PIK3R2	c.1627G>A	p.E543K	Missense	13/16	-
19-50918095-C-G	POLD1	c.2412C>G	p.I804M	Missense	20/27	-
10-43597964-G-T	RET	c.512G>T	p.R171M	Missense	3/20	-
8-92988149-C-G	RUNX1T1	c.1221G>C	p.E407D	Missense	9/11	-
4-20521012-T-C	SLIT2	c.1066T>C	p.Y356H	Missense	12/37	-
3-181430758-G-T	SOX2	c.610G>T	p.A204S	Missense	1/1	-
9-27203108-G-A	TEK	c.2200G>A	p.E734K	Missense	13/23	-
9-27203106-C-A	TEK	c.2198C>A	p.P733Q	Missense	13/23	-
11-118365431-G-T	KMT2A	c.5312G>T	p.W1771L	Missense	18/36	-
1-16460408-C-T	EPHA2	c.1685G>A	p.R562K	Missense	9/17	-
10-43623566-C-G	RET	c.3194C>G	p.S1065*	Nonsense	20/20	-
7-55231465-G-T	EGFR	c.1671G>T	p.Q557H	Missense	14/28	-
1-11298512-T-A	MTOR	c.1949A>T	p.Q650L	Missense	12/58	-
7-42005915-A-G	GLI3	c.2756T>C	p.L919P	Missense	15/15	-
7-41730089-A-T	INHBA	c.440T>A	p.L147Q	Missense	3/3	-
19-19256787-G-A	MEF2B	c.926C>T	p.A309V	Missense	9/9	-
9-36923357-A-G	PAX5	c.905T>C	p.V302A	Missense	7/10	-
3-47125469-G-A	SETD2	c.5801C>T	p.P1934L	Missense	12/21	-
1-158581135-C-A	SPTA1	c.7179G>T	p.Q2393H	Missense	52/52	-
3-41266483-G-C	CTNNB1	c.280G>C	p.V94L	Missense	4/15	-
3-134670574-T-A	EPHB1	c.485T>A	p.V162D	Missense	3/16	-
15-91295155-C-T	BLM	c.938C>T	p.S313F	Missense	4/22	-
16-23649258-C-G	PALB2	c.124G>C	p.E42Q	Missense	3/13	-
5-131924570-A-T	RAD50	c.1243A>T	p.M415L	Missense	8/25	-
16-68857456-G-T	CDH1	c.2091G>T	p.K697N	Missense	13/16	-
14-95590996-C-A	DICER1	c.913G>T	p.D305Y	Missense	8/27	-
12-56487641-G-A	ERBB3	c.1574G>A	p.R525Q	Missense	13/28	-
12-49420901-G-C	KMT2D	c.14848C>G	p.L4950V	Missense	49/55	-
2-141607817-G-T	LRP1B	c.4793C>A	p.T1598K	Missense	29/91	-
4-110890251-G-A	EGF	c.1700G>A	p.R567H	Missense	11/24	-
X-70595083-C-A	TAF1	c.479C>A	p.P140H	Missense	4/38	-
8-139278053-C-A	FAM135B	c.190G>T	p.D64Y	Missense	4/20	-
4-187557992-T-A	FAT1	c.3719A>T	p.D1240V	Missense	5/27	-
9-137313610-C-G	RXRA	c.869C>G	p.S290*	Nonsense	6/10	-
3-47098571-C-T	SETD2	c.6703G>A	p.V2235I	Missense	15/21	-
4-55146576-G-T	PDGFRA	c.2250G>T	p.E750D	Missense	16/23	-
2-212543803-G-T	ERBB4	c.1596C>A	p.C532*	Nonsense	13/28	-
11-22646285-C-G	FANCF	c.1072G>C	p.A358P	Missense	1/1	-
3-119642260-T-C	GSK3B	c.437A>G	p.Y146C	Missense	4/11	-
3-138433450-C-T	PIK3CB	c.1162G>A	p.D388N	Missense	9/24	-
14-95562981-TCTC-T	DICER1	c.4273_4275delGAG	p.E1425del	InFrameDeletion	23/27	-
1-11259340-G-A	MTOR	c.4228C>T	p.P1410S	Missense	28/58	-
5-180048693-G-T	FLT4	c.1869C>A	p.S623R	Missense	13/30	-
3-38180282-C-A	MYD88	c.130C>A	p.R31S	Missense	1/5	-
2-178095740-G-C	NFE2L2	c.1591C>G	p.H531D	Missense	5/5	-
6-394947-C-A	IRF4	c.343C>A	p.Q115K	Missense	3/9	-
14-81534626-C-A	TSHR	c.271C>A	p.Q91K	Missense	3/10	-
20-52192785-C-G	ZNF217	c.2518G>C	p.E840Q	Missense	4/6	-
2-141747224-T-C	LRP1B	c.2647A>G	p.N883D	Missense	17/91	-
16-3788626-C-A	CREBBP	c.4328G>T	p.R1443L	Missense	26/31	-
5-180049806-C-T	FLT4	c.1582G>A	p.V528M	Missense	12/30	-
18-19751428-G-C	GATA6	c.323G>C	p.S108T	Missense	2/7	-
12-57552421-G-C	LRP1	c.1798G>C	p.G600R	Missense	11/89	-
2-141081546-C-A	LRP1B	c.12430G>T	p.G4144C	Missense	81/91	-
1-43783709-C-A	TIE1	c.2888C>A	p.A963E	Missense	17/23	-
11-108141854-G-A	ATM	c.2902G>A	p.E968K	Missense	19/63	-
7-55231447-G-C	EGFR	c.1653G>C	p.E551D	Missense	14/28	-
7-78130922-T-C	MAGI2	c.937A>G	p.T313A	Missense	5/22	-
21-36259273-C-A	RUNX1	c.218G>T	p.S73I	Missense	4/9	-
9-5126781-T-C	JAK2	c.3389T>C	p.M1130T	Missense	25/25	-
1-150551958-C-T	MCL1	c.49G>A	p.G17R	Missense	1/3	-
1-16259987-G-C	SPEN	c.7252G>C	p.E2418Q	Missense	11/15	-
16-23635399-A-G	PALB2	c.2765T>C	p.I922T	Missense	8/13	-
18-19757040-G-A	GATA6	c.1260G>A	p.M420I	Missense	3/7	-
12-57577255-C-G	LRP1	c.5756C>G	p.S1919C	Missense	35/89	-
12-57577234-C-G	LRP1	c.5735C>G	p.S1912*	Nonsense	35/89	-
12-69968308-A-T	FRS2	c.1100A>T	p.D367V	Missense	9/9	-
5-156665188-A-G	ITK	c.838A>G	p.K280E	Missense	9/17	-
7-55249013-A-ACCCCCC	EGFR	c.2311_2312insCCCCCC	p.N771delinsTPH	MultiAAMissense	20/28	-
12-49444744-G-A	KMT2D	c.2722C>T	p.L908=	Synonymous	11/55	-
9-27197504-C-T	TEK	c.1816C>T	p.H606Y	Missense	12/23	-
2-212530104-G-C	ERBB4	c.1815C>G	p.F605L	Missense	15/28	-
16-56868064-C-G	NUP93	c.1562C>G	p.P521R	Missense	14/22	-
9-2076289-A-G	SMARCA2	c.1996A>G	p.S666G	Missense	13/34	-
3-37081704-C-G	MLH1	c.1586C>G	p.S529C	Missense	14/19	-
5-131927058-C-T	RAD50	c.1595C>T	p.T532I	Missense	10/25	-
12-12870996-G-T	CDKN1B	c.223G>T	p.E75*	Nonsense	1/3	-
2-25469955-G-C	DNMT3A	c.1087C>G	p.P363A	Missense	9/23	-
10-43606839-A-T	RET	c.1448A>T	p.Y483F	Missense	7/20	-
1-162740185-A-G	DDR2	c.1387A>G	p.S463G	Missense	12/18	-
13-28903793-A-T	FLT1	c.2666T>A	p.L889Q	Missense	19/30	-
12-57596983-G-C	LRP1	c.10731G>C	p.E3577D	Missense	69/89	-
4-20570534-G-C	SLIT2	c.2995G>C	p.V999L	Missense	29/37	-
11-108204648-A-G	ATM	c.7963A>G	p.K2655E	Missense	54/63	-
5-233598-A-G	SDHA	c.902A>G	p.Y301C	Missense	8/15	-
4-55156574-C-A	PDGFRA	c.2975C>A	p.T992N	Missense	22/23	-
16-2098729-T-A	TSC2	c.113T>A	p.F38Y	Missense	2/42	-
16-89809255-C-T	FANCA	c.3718G>A	p.E1240K	Missense	37/43	-
9-5090457-C-A	JAK2	c.2773C>A	p.L925I	Missense	21/25	-
16-23640589-G-A	PALB2	c.2522C>T	p.T841I	Missense	6/13	-
2-60689249-A-T	BCL11A	c.798T>A	p.F266L	Missense	4/4	-
4-187549770-A-C	FAT1	c.4471T>G	p.Y1491D	Missense	8/27	-
10-96612594-G-T	CYP2C19	c.1396G>T	p.D466Y	Missense	9/9	-
12-21626571-C-T	RECQL	c.1361G>A	p.R454H	Missense	12/15	-
17-57119180-G-A	TRIM37	c.1747C>T	p.P583S	Missense	17/24	-
4-1343490-A-G	UVSSA	c.277A>G	p.T93A	Missense	3/14	-
19-44050108-C-T	XRCC1	c.1483G>A	p.V495M	Missense	14/17	-
1-85733312-A-C	BCL10	c.700T>G	p.*234Gext*6	Missense	3/3	-
3-105470341-C-A	CBLB	c.688G>T	p.V230F	Missense	5/19	-
3-41278175-G-A	CTNNB1	c.2051G>A	p.R684K	Missense	13/15	-
16-72992645-T-G	ZFHX3	c.1400A>C	p.E467A	Missense	2/10	-
16-23646693-C-G	PALB2	c.1174G>C	p.E392Q	Missense	4/13	-
19-44047589-C-A	XRCC1	c.1857G>T	p.Q619H	Missense	17/17	-
16-23641545-C-G	PALB2	c.1930G>C	p.G644R	Missense	5/13	-
17-29654589-G-T	NF1	c.5341G>T	p.D1781Y	Missense	38/58	-
13-28896483-G-C	FLT1	c.2967C>G	p.F989L	Missense	22/30	-
6-135521460-G-T	MYB	c.1857G>T	p.L619=	Synonymous	13/16	-
1-115258771-T-A	NRAS	c.11A>T	p.Y4F	Missense	2/7	-
2-223085013-T-C	PAX3	c.1019A>G	p.H340R	Missense	7/9	-
2-239159220-C-T	PER2	c.3439G>A	p.V1147I	Missense	21/23	-
9-98231270-G-C	PTCH1	c.2013C>G	p.H671Q	Missense	14/24	-
17-70120511-C-G	SOX9	c.1513C>G	p.Q505E	Missense	3/3	-
16-23649410-T-C	PALB2	c.89A>G	p.K30R	Missense	2/13	-
10-98064322-T-C	DNTT	c.68T>C	p.M23T	Missense	1/11	-
14-62187147-C-T	HIF1A	c.83C>T	p.S28F	Missense	2/15	-
4-178256920-G-C	NEIL3	c.357G>C	p.L119F	Missense	3/10	-
11-85723393-A-C	PICALM	c.589T>G	p.F197V	Missense	6/20	-
3-48455369-C-A	PLXNB1	c.4321G>T	p.V1441L	Missense	22/38	-
3-121206455-C-A	POLQ	c.5323G>T	p.G1775C	Missense	16/30	-
8-69021748-G-T	PREX2	c.3036G>T	p.R1012S	Missense	25/40	-
12-21636506-C-A	RECQL	c.504G>T	p.E168D	Missense	6/15	-
17-78318983-G-T	RNF213	c.6848G>T	p.G2283V	Missense	29/68	-
18-61326686-C-A	SERPINB3	c.298G>T	p.E100*	Nonsense	4/8	-
3-47161841-C-T	SETD2	c.4285G>A	p.V1429M	Missense	3/21	-
6-146256427-T-A	SHPRH	c.2720A>T	p.D907V	Missense	12/30	-
1-158590061-C-T	SPTA1	c.6316G>A	p.D2106N	Missense	44/52	-
20-36012789-G-T	SRC	c.233G>T	p.R78M	Missense	4/14	-
3-176752032-T-A	TBL1XR1	c.1204A>T	p.T402S	Missense	13/16	-
14-90432534-G-A	TDP1	c.603G>A	p.Q201=	Synonymous	4/17	-
3-10183715-G-T	VHL	c.184G>T	p.V62L	Missense	1/3	-
2-61719795-C-A	XPO1	c.1473G>T	p.W491C	Missense	14/25	-
2-47612314-A-G	EPCAM	c.868A>G	p.R290G	Missense	8/9	-
19-50902309-C-T	POLD1	c.201C>T	p.D67=	Synonymous	2/27	-
19-50905291-G-A	POLD1	c.499G>A	p.E167K	Missense	5/27	-
22-29130579-C-G	CHEK2	c.131G>C	p.S44T	Missense	2/15	-
19-10602602-G-A	KEAP1	c.976C>T	p.R326C	Missense	3/6	-
5-80063866-G-A	MSH3	c.2011G>A	p.V671I	Missense	14/24	-
X-47044716-A-T	RBM10	c.2116A>T	p.R706*	Nonsense	19/24	-
17-12032464-GG-TA	MAP2K4	c.900_901delinsTA	p.L300_A301delinsFT	MultiAAMissense	9/11	-
4-143352337-C-A	INPP4B	c.76G>T	p.D26Y	Missense	4/26	-
X-47044889-G-T	RBM10	c.2215G>T	p.E739*	Nonsense	20/24	-
16-23647368-C-T	PALB2	c.499G>A	p.D167N	Missense	4/13	-
1-27057688-G-T	ARID1A	c.1396G>T	p.G466C	Missense	3/20	-
X-152815159-G-T	ATP2B3	c.1543G>T	p.A515S	Missense	9/20	-
19-4409044-C-T	CHAF1A	c.248C>T	p.S83F	Missense	3/15	-
5-10988246-G-T	CTNND2	c.3320C>A	p.T1107N	Missense	20/22	-
5-11565087-C-A	CTNND2	c.256G>T	p.G86*	Nonsense	3/22	-
3-142274845-C-A	ATR	c.2215G>T	p.D739Y	Missense	10/47	-
X-37027291-C-A	FAM47C	c.808C>A	p.L270I	Missense	1/1	-
10-123276902-C-A	FGFR2	c.1015G>T	p.E339*	Nonsense	8/18	-
1-155205080-G-A	GBA	c.1411C>T	p.Q471*	Nonsense	10/11	-
16-9858201-C-A	GRIN2A	c.3200G>T	p.R1067L	Missense	13/13	-
2-187487140-A-T	ITGAV	c.391A>T	p.K131*	Nonsense	3/30	-
X-53223743-G-T	KDM5C	c.3616C>A	p.Q1206K	Missense	23/26	-
2-141607744-C-A	LRP1B	c.4866G>T	p.W1622C	Missense	29/91	-
1-76349448-G-T	MSH4	c.2049G>T	p.M683I	Missense	15/20	-
6-135516931-A-G	MYB	c.994A>G	p.I332V	Missense	9/16	-
5-80040413-C-T	MSH3	c.1742C>T	p.T581I	Missense	12/24	-
16-23641722-C-T	PALB2	c.1753G>A	p.D585N	Missense	5/13	-
1-243668594-G-T	AKT3	c.1397C>A	p.P466Q	Missense	14/14	-
1-27105859-G-T	ARID1A	c.5470G>T	p.V1824L	Missense	20/20	-
1-116943540-G-T	ATP1A1	c.2630G>T	p.G877V	Missense	19/23	-
X-76939462-G-T	ATRX	c.1286C>A	p.T429N	Missense	9/35	-
1-162729646-G-T	DDR2	c.732G>T	p.Q244H	Missense	8/18	-
3-10136932-C-T	FANCD2	c.4012C>T	p.L1338F	Missense	41/44	-
7-81359082-C-A	HGF	c.879G>T	p.M293I	Missense	8/18	-
5-35874551-G-T	IL7R	c.707G>T	p.G236V	Missense	6/8	-
4-55964334-A-G	KDR	c.2479T>C	p.W827R	Missense	17/30	-
7-151900059-C-T	KMT2C	c.4052G>A	p.R1351K	Missense	26/59	-
6-32188298-C-T	NOTCH4	c.1043G>A	p.G348D	Missense	6/30	-
4-55127446-C-A	PDGFRA	c.234C>A	p.S78R	Missense	3/23	-
8-68984790-C-A	PREX2	c.1554C>A	p.D518E	Missense	14/40	-
8-68989697-G-T	PREX2	c.1635G>T	p.M545I	Missense	15/40	-
9-98238347-G-C	PTCH1	c.1697C>G	p.P566R	Missense	12/24	-
22-22221708-C-A	MAPK1	c.23G>T	p.G8V	Missense	1/9	-
X-70510493-G-T	NONO	c.6G>T	p.Q2H	Missense	3/12	-
3-121203987-T-C	POLQ	c.5674A>G	p.I1892V	Missense	17/30	-
2-55792038-C-A	PPP4R3B	c.2075G>T	p.S692I	Missense	14/17	-
5-23522906-C-A	PRDM9	c.794C>A	p.S265Y	Missense	8/11	-
11-108122584-C-T	ATM	c.1628C>T	p.T543I	Missense	11/63	-
5-112177947-C-T	APC	c.6656C>T	p.A2219V	Missense	16/16	-
11-85988077-A-G	EED	c.1022A>G	p.D341G	Missense	10/12	-
8-139165221-C-G	FAM135B	c.1497G>C	p.Q499H	Missense	13/20	-
7-75172208-G-C	HIP1	c.2852C>G	p.A951G	Missense	28/31	-
4-87655550-T-TTTG	PTPN13	c.1953_1954insTTG	p.T651_V652insL	InFrameInsertion	13/48	-
X-48896827-CC-GA	TFE3	c.338_339delGGinsTC	p.R113I	Missense	3/10	-
2-215645880-C-G	BARD1	c.718G>C	p.V240L	Missense	4/11	-
2-215645880-C-A	BARD1	c.718G>T	p.V240L	Missense	4/11	-
4-178274643-G-T	NEIL3	c.1221G>T	p.K407N	Missense	8/10	-
11-102207667-G-C	BIRC3	c.1649G>C	p.R550T	Missense	9/9	-
13-73355086-A-G	DIS3	c.284T>C	p.L95P	Missense	2/21	-
2-30143196-C-A	ALK	c.330G>T	p.W110C	Missense	1/29	-
4-55972001-G-T	KDR	c.1643C>A	p.T548N	Missense	12/30	-
X-47044743-A-T	RBM10	c.2143A>T	p.K715*	Nonsense	19/24	-
X-96139694-G-A	RPA4	c.385G>A	p.G129S	Missense	1/1	-
1-16256919-C-T	SPEN	c.4184C>T	p.A1395V	Missense	11/15	-
12-115112459-C-A	TBX3	c.1221G>T	p.R407=	Synonymous	6/7	-
14-90499554-T-A	TDP1	c.1749T>A	p.S583R	Missense	16/17	-
5-1294228-T-G	TERT	c.773A>C	p.H258P	Missense	2/16	-
4-55565909-A-G	KIT	c.733A>G	p.T245A	Missense	4/21	-
6-93964474-A-G	EPHA7	c.2423T>C	p.I808T	Missense	14/17	-
1-32741560-A-T	LCK	c.527A>T	p.E176V	Missense	7/13	-
4-178274830-G-C	NEIL3	c.1408G>C	p.A470P	Missense	8/10	-
1-76349438-G-T	MSH4	c.2039G>T	p.G680V	Missense	15/20	-
17-29676146-C-G	NF1	c.7198C>G	p.H2400D	Missense	49/58	-
1-158651413-C-A	SPTA1	c.435G>T	p.E145D	Missense	4/52	-
17-38555158-T-C	TOP2A	c.3320A>G	p.D1107G	Missense	26/35	-
1-32742086-G-T	LCK	c.780G>T	p.W260C	Missense	8/13	-
1-158607971-C-G	SPTA1	c.5041G>C	p.V1681L	Missense	36/52	-
2-128030487-T-A	ERCC3	c.1781A>T	p.Q594L	Missense	11/15	-
2-141473597-T-C	LRP1B	c.5968A>G	p.I1990V	Missense	37/91	-
1-11301728-C-T	MTOR	c.1423G>A	p.A475T	Missense	10/58	-
5-131915116-A-T	RAD50	c.473A>T	p.H158L	Missense	4/25	-
21-44513322-G-A	U2AF1	c.613C>T	p.R205W	Missense	8/8	-
5-82500667-C-G	XRCC4	c.672C>G	p.D224E	Missense	6/8	-
19-7688747-CGCAGCTCCAGGT-AGCAGGG	XAB2	c.977_989delinsCCCTGCT	p.D326_R330delinsALL	MultiAAMissense	8/19	-
6-32166207-G-A	NOTCH4	c.4747C>T	p.R1583C	Missense	26/30	-
14-20923808-C-G	APEX1	c.4C>G	p.P2A	Missense	2/5	-
11-108173733-C-G	ATM	c.5473C>G	p.Q1825E	Missense	36/63	-
8-109229637-T-C	EIF3E	c.775A>G	p.T259A	Missense	8/13	-
8-139165274-G-C	FAM135B	c.1444C>G	p.P482A	Missense	13/20	-
X-37028885-T-A	FAM47C	c.2402T>A	p.L801Q	Missense	1/1	-
14-45636238-G-C	FANCM	c.1874G>C	p.S625T	Missense	11/23	-
3-138664706-G-C	FOXL2	c.859C>G	p.P287A	Missense	1/1	-
10-84738732-G-A	NRG3	c.1439G>A	p.G480E	Missense	8/9	-
16-23647491-C-G	PALB2	c.376G>C	p.E126Q	Missense	4/13	-
13-67802561-C-G	PCDH9	c.12G>C	p.R4S	Missense	2/5	-
15-89876469-C-A	POLG	c.517G>T	p.E173*	Nonsense	2/23	-
12-111856220-G-T	SH2B3	c.271G>T	p.D91Y	Missense	2/8	-
7-152008996-A-T	KMT2C	c.626T>A	p.V209E	Missense	5/59	-
16-89846317-C-T	FANCA	c.1675G>A	p.E559K	Missense	18/43	-
16-23641789-C-T	PALB2	c.1686G>A	p.G562=	Synonymous	5/13	-
2-169851960-C-A	ABCB11	c.510G>T	p.Q170H	Missense	7/28	-
17-59871069-T-A	BRIP1	c.1362A>T	p.E454D	Missense	10/20	-
X-100630272-T-C	BTK	c.1A>G	p.M1?	Missense	2/19	-
10-64968473-T-A	JMJD1C	c.2956A>T	p.T986S	Missense	10/26	-
2-141598646-C-A	LRP1B	c.4955G>T	p.R1652I	Missense	30/91	-
19-15308384-G-A	NOTCH3	c.124C>T	p.P42S	Missense	2/33	-
12-133225532-C-A	POLE	c.4132G>T	p.G1378C	Missense	32/49	-
18-51820622-A-G	POLI	c.2008A>G	p.R670G	Missense	10/10	-
7-95813730-C-A	SLC25A13	c.1036G>T	p.V346L	Missense	11/18	-
14-32563279-A-G	ARHGAP5	c.3404A>G	p.N1135S	Missense	2/7	-
X-76940459-C-T	ATRX	c.634G>A	p.D212N	Missense	8/35	-
16-11001813-T-C	CIITA	c.2464T>C	p.W822R	Missense	11/20	-
4-84384670-C-G	ABRAXAS1	c.773G>C	p.R258T	Missense	8/9	-
14-45658188-C-A	FANCM	c.4963C>A	p.Q1655K	Missense	20/23	-
7-95761142-G-A	SLC25A13	c.1504C>T	p.P502S	Missense	15/18	-
1-158596643-A-G	SPTA1	c.5819T>C	p.V1940A	Missense	41/52	-
12-115118776-C-A	TBX3	c.565G>T	p.D189Y	Missense	2/7	-
11-61076455-C-A	DDB1	c.2661G>T	p.T887=	Synonymous	21/27	-
15-99500456-C-T	IGF1R	c.3889C>T	p.P1297S	Missense	21/21	-
2-141597597-A-C	LRP1B	c.5172T>G	p.N1724K	Missense	31/91	-
17-29528490-G-C	NF1	c.1247G>C	p.R416P	Missense	11/58	-
15-99451961-G-T	IGF1R	c.1295G>T	p.W432L	Missense	6/21	-
5-23524494-G-T	PRDM9	c.1002G>T	p.Q334H	Missense	10/11	-
X-47041711-A-T	RBM10	c.1936A>T	p.K646*	Nonsense	17/24	-
14-99640606-C-A	BCL11B	c.2567G>T	p.C856F	Missense	4/4	-
7-148481136-T-G	CUL1	c.1265T>G	p.L422R	Missense	11/22	-
11-77047325-C-T	PAK1	c.1219G>A	p.D407N	Missense	13/15	-
X-47039327-T-C	RBM10	c.950T>C	p.L317P	Missense	10/24	-
4-39322960-G-A	RFC1	c.755C>T	p.S252L	Missense	8/25	-
17-41245417-TAGTAAA-T	BRCA1	c.2125_2130delTTTACT	p.F709_T710del	InFrameDeletion	10/23	-
2-29551335-C-A	ALK	c.1295G>T	p.G432V	Missense	6/29	-
5-180043414-G-T	FLT4	c.3172C>A	p.L1058I	Missense	23/30	-
10-43607571-C-A	RET	c.1547C>A	p.P516H	Missense	8/20	-
1-16255142-G-T	SPEN	c.2407G>T	p.E803*	Nonsense	11/15	-
X-123184155-A-T	STAG2	c.1013A>T	p.D338V	Missense	11/35	-
10-104377105-A-G	SUFU	c.1216A>G	p.I406V	Missense	10/12	-
8-139164264-G-T	FAM135B	c.2454C>A	p.D818E	Missense	13/20	-
8-139165082-C-G	FAM135B	c.1636G>C	p.G546R	Missense	13/20	-
14-45620625-T-A	FANCM	c.944T>A	p.L315*	Nonsense	5/23	-
19-41758341-G-T	AXL	c.1797G>T	p.R599S	Missense	15/20	-
4-25678024-C-T	SLC34A2	c.1726C>T	p.Q576*	Nonsense	13/13	-
16-72992745-T-C	ZFHX3	c.1300A>G	p.K434E	Missense	2/10	-
7-142460284-G-A	PRSS1	c.457G>A	p.D153N	Missense	4/5	-
17-62499074-T-A	DDX5	c.953A>T	p.D318V	Missense	8/13	-
4-55971128-G-A	KDR	c.1669C>T	p.P557S	Missense	13/30	-
10-70405432-C-G	TET1	c.2946C>G	p.I982M	Missense	4/12	-
5-112176494-G-A	APC	c.5203G>A	p.G1735R	Missense	16/16	-
14-95556842-T-C	DICER1	c.5762A>G	p.N1921S	Missense	27/27	-
6-106553651-C-G	PRDM1	c.1616C>G	p.A539G	Missense	5/7	-
16-9858252-C-G	GRIN2A	c.3149G>C	p.R1050T	Missense	13/13	-
2-141200100-C-A	LRP1B	c.10387G>T	p.A3463S	Missense	66/91	-
16-23614886-G-A	PALB2	c.3455C>T	p.P1152L	Missense	13/13	-
8-68942798-A-G	PREX2	c.610A>G	p.M204V	Missense	6/40	-
11-119155697-C-A	CBL	c.1450C>A	p.P484T	Missense	10/16	-
16-10995408-G-A	CIITA	c.474G>A	p.W158*	Nonsense	6/20	-
3-48627760-C-G	COL7A1	c.1936G>C	p.D646H	Missense	16/119	-
7-42063198-C-T	GLI3	c.1366G>A	p.E456K	Missense	10/15	-
6-114270411-C-T	HDAC2	c.653G>A	p.G218E	Missense	7/14	-
19-17949101-G-T	JAK3	c.1540C>A	p.H514N	Missense	11/24	-
17-29685640-A-T	NF1	c.8113A>T	p.S2705C	Missense	55/58	-
16-23634345-T-A	PALB2	c.2941A>T	p.S981C	Missense	9/13	-
9-116172360-C-A	POLE3	c.127G>T	p.V43F	Missense	3/5	-
18-20562317-C-A	RBBP8	c.565C>A	p.Q189K	Missense	7/19	-
1-158623130-A-T	SPTA1	c.3122T>A	p.M1041K	Missense	22/52	-
13-26959424-C-G	CDK8	c.591C>G	p.F197L	Missense	6/13	-
4-54915422-C-G	CHIC2	c.170G>C	p.G57A	Missense	2/6	-
12-56488302-G-C	ERBB3	c.1821G>C	p.Q607H	Missense	15/28	-
5-60240772-C-T	ERCC8	c.64G>A	p.E22K	Missense	1/12	-
9-35078326-C-G	FANCG	c.322G>C	p.E108Q	Missense	4/14	-
X-132887628-C-G	GPC3	c.913G>C	p.E305Q	Missense	3/8	-
12-124137084-C-G	GTF2H3	c.433C>G	p.H145D	Missense	6/13	-
5-55253113-G-C	IL6ST	c.980C>G	p.S327C	Missense	9/17	-
19-48624445-C-A	LIG1	c.2367G>T	p.E789D	Missense	24/28	-
12-124824684-G-T	NCOR2	c.5555C>A	p.S1852Y	Missense	39/49	-
6-32163506-C-A	NOTCH4	c.5720G>T	p.G1907V	Missense	30/30	-
19-52693350-A-T	PPP2R1A	c.1A>T	p.M1?	Missense	1/15	-
2-109392288-C-T	RANBP2	c.8393C>T	p.S2798F	Missense	24/29	-
11-32456858-G-A	WT1	c.34C>T	p.P17S	Missense	1/10	-
16-23647461-T-C	PALB2	c.406A>G	p.S136G	Missense	4/13	-
2-141259398-C-G	LRP1B	c.8708G>C	p.C2903S	Missense	55/91	-
2-141079618-C-A	LRP1B	c.12554G>T	p.C4185F	Missense	82/91	-
1-76378474-G-T	MSH4	c.2713G>T	p.D905Y	Missense	20/20	-
3-126724057-G-T	PLXNA1	c.1868G>T	p.R623L	Missense	7/32	-
20-43959190-G-C	SDC4	c.261C>G	p.N87K	Missense	4/5	-
4-106157591-A-T	TET2	c.2492A>T	p.Q831L	Missense	3/11	-
11-32417835-G-A	WT1	c.1217C>T	p.S411F	Missense	7/10	-
6-41904424-A-C	CCND3	c.584T>G	p.F195C	Missense	4/5	-
22-19171040-C-A	CLTCL1	c.4690G>T	p.E1564*	Nonsense	30/33	-
11-107966331-G-C	CUL5	c.1818G>C	p.W606C	Missense	16/19	-
8-139164295-G-A	FAM135B	c.2423C>T	p.S808F	Missense	13/20	-
10-70442684-C-T	TET1	c.5006C>T	p.A1669V	Missense	10/12	-
16-72828396-G-A	ZFHX3	c.8185C>T	p.H2729Y	Missense	9/10	-
1-76282183-C-T	MSH4	c.941C>T	p.S314L	Missense	6/20	-
1-35656533-G-C	SFPQ	c.1081C>G	p.Q361E	Missense	3/10	-
16-23619315-G-C	PALB2	c.3220C>G	p.L1074V	Missense	12/13	-
8-41582045-C-T	ANK1	c.640G>A	p.A214T	Missense	7/43	-
16-88947829-C-G	CBFA2T3	c.1272G>C	p.Q424H	Missense	9/12	-
7-137567224-G-A	CREB3L2	c.1421C>T	p.P474L	Missense	11/12	-
13-29068967-C-A	FLT1	c.14G>T	p.W5L	Missense	1/30	-
3-138664991-G-T	FOXL2	c.574C>A	p.P192T	Missense	1/1	-
7-42063147-C-T	GLI3	c.1417G>A	p.E473K	Missense	10/15	-
9-80336358-C-T	GNAQ	c.961G>A	p.D321N	Missense	7/7	-
12-49425055-C-A	KMT2D	c.13433G>T	p.R4478L	Missense	40/55	-
1-150551376-C-G	MCL1	c.631G>C	p.E211Q	Missense	1/3	-
11-85685842-C-T	PICALM	c.1853G>A	p.G618E	Missense	19/20	-
2-190728875-G-A	PMS1	c.2263G>A	p.A755T	Missense	10/13	-
7-44116143-T-C	POLM	c.800A>G	p.E267G	Missense	6/11	-
5-23509593-C-A	PRDM9	c.84C>A	p.F28L	Missense	3/11	-
11-60671286-G-A	PRPF19	c.67C>T	p.H23Y	Missense	2/16	-
3-51697428-G-T	RAD54L2	c.4396G>T	p.G1466W	Missense	23/23	-
3-51696873-G-T	RAD54L2	c.3841G>T	p.V1281L	Missense	23/23	-
2-152314405-G-A	RIF1	c.2783G>A	p.R928Q	Missense	24/36	-
X-96139944-G-T	RPA4	c.635G>T	p.C212F	Missense	1/1	-
9-101894832-G-A	TGFBR1	c.385G>A	p.V129I	Missense	3/9	-
9-135771852-C-A	TSC1	c.3265G>T	p.G1089C	Missense	23/23	-
14-81610029-G-T	TSHR	c.1627G>T	p.V543F	Missense	10/10	-
3-10191612-C-T	VHL	c.605C>T	p.T202I	Missense	3/3	-
17-30264275-C-G	SUZ12	c.10C>G	p.Q4E	Missense	1/16	-
12-124848314-G-C	NCOR2	c.2839C>G	p.P947A	Missense	23/49	-
16-23646944-G-C	PALB2	c.923C>G	p.A308G	Missense	4/13	-
16-23646924-G-T	PALB2	c.943C>A	p.L315M	Missense	4/13	-
10-123298157-C-A	FGFR2	c.697G>T	p.V233L	Missense	6/18	-
X-70344971-A-G	MED12	c.2201A>G	p.Y734C	Missense	15/45	-
10-104375054-G-C	SUFU	c.1052G>C	p.S351T	Missense	9/12	-
4-106196694-A-T	TET2	c.5027A>T	p.H1676L	Missense	11/11	-
3-142232423-C-T	ATR	c.4561G>A	p.D1521N	Missense	26/47	-
5-176524336-A-T	FGFR4	c.2197A>T	p.R733W	Missense	17/18	-
17-17118305-C-T	FLCN	c.1532G>A	p.W511*	Nonsense	13/14	-
4-55971119-G-A	KDR	c.1678C>T	p.Q560*	Nonsense	13/30	-
9-20620794-G-T	MLLT3	c.52C>A	p.Q18K	Missense	2/11	-
17-63534442-T-A	AXIN2	c.1079A>T	p.K360M	Missense	5/11	-
16-23641257-G-C	PALB2	c.2218C>G	p.Q740E	Missense	5/13	-
17-59761036-T-A	BRIP1	c.3371A>T	p.E1124V	Missense	20/20	-
5-24535329-C-A	CDH10	c.706G>T	p.V236F	Missense	5/12	-
11-118635946-C-G	DDX6	c.617G>C	p.R206P	Missense	6/14	-
8-139149413-G-T	FAM135B	c.3992C>A	p.T1331N	Missense	19/20	-
3-59999857-C-A	FHIT	c.125G>T	p.R42L	Missense	6/10	-
4-25674865-CCAT-C	SLC34A2	c.1208_1210delTCA	p.I403del	InFrameDeletion	10/13	-
2-212537966-C-T	ERBB4	c.1639G>A	p.E547K	Missense	14/28	-
X-47040995-C-T	RBM10	c.1525C>T	p.Q509*	Nonsense	14/24	-
4-55953780-C-A	KDR	c.3656G>T	p.G1219V	Missense	27/30	-
1-45798289-C-A	MUTYH	c.563G>T	p.G188V	Missense	8/16	-
13-25074506-C-A	PARP4	c.349G>T	p.G117C	Missense	4/34	-
6-106553256-C-A	PRDM1	c.1221C>A	p.N407K	Missense	5/7	-
1-3328945-G-T	PRDM16	c.2184G>T	p.Q728H	Missense	9/17	-
7-73661028-C-A	RFC2	c.398G>T	p.G133V	Missense	5/11	-
6-169632151-C-G	THBS2	c.2075G>C	p.G692A	Missense	13/22	-
2-237489846-G-C	ACKR3	c.738G>C	p.E246D	Missense	2/2	-
20-54945670-C-T	AURKA	c.900G>A	p.M300I	Missense	8/9	-
11-125513755-C-G	CHEK1	c.883C>G	p.Q295E	Missense	9/13	-
5-11411747-C-G	CTNND2	c.340G>C	p.E114Q	Missense	5/22	-
22-41572937-C-G	EP300	c.5222C>G	p.S1741C	Missense	31/31	-
22-41573386-C-G	EP300	c.5671C>G	p.Q1891E	Missense	31/31	-
1-8073324-C-T	ERRFI1	c.1335G>A	p.M445I	Missense	4/4	-
9-5050746-G-C	JAK2	c.529G>C	p.E177Q	Missense	6/25	-
7-151876929-G-C	KMT2C	c.7432C>G	p.H2478D	Missense	37/59	-
15-40916600-G-A	KNL1	c.4138G>A	p.D1380N	Missense	10/26	-
1-120462938-T-C	NOTCH2	c.5393A>G	p.D1798G	Missense	30/34	-
4-1955231-C-G	NSD2	c.2318C>G	p.S773*	Nonsense	12/22	-
16-56855431-G-A	NUP93	c.580G>A	p.E194K	Missense	7/22	-
10-103344568-C-T	POLL	c.682G>A	p.E228K	Missense	5/9	-
10-72360573-G-T	PRF1	c.86C>A	p.S29*	Nonsense	2/3	-
2-109365525-G-A	RANBP2	c.1213G>A	p.D405N	Missense	9/29	-
7-73649939-C-T	RFC2	c.877G>A	p.E293K	Missense	10/11	-
18-42281527-C-A	SETBP1	c.216C>A	p.N72K	Missense	2/6	-
1-62916299-C-T	USP1	c.2005C>T	p.L669F	Missense	9/9	-
17-80789435-G-T	ZNF750	c.896C>A	p.P299Q	Missense	2/3	-
1-27106858-G-T	ARID1A	c.6469G>T	p.D2157Y	Missense	20/20	-
3-8983296-A-T	RAD18	c.459T>A	p.N153K	Missense	5/13	-
3-133320121-A-T	TOPBP1	c.4542T>A	p.N1514K	Missense	28/28	-
4-1346866-T-C	UVSSA	c.599T>C	p.F200S	Missense	5/14	-
7-26236993-GCAGCCATGGCAGCATCAACCT-G	HNRNPA2B1	c.185_205del21	p.E62_A68del	InFrameDeletion	3/11	-
15-80464523-AGAGC-CT	FAH	c.639_643delinsCT	p.E214_P215delinsS	MultiAAMissense	8/14	-
9-5050780-G-T	JAK2	c.563G>T	p.R188I	Missense	6/25	-
2-234669217-T-C	UGT1A1	c.284T>C	p.L95P	Missense	1/5	-
5-11384843-G-A	CTNND2	c.1111C>T	p.Q371*	Nonsense	7/22	-
10-27112113-G-A	ABI1	c.239C>T	p.A80V	Missense	2/11	-
2-215674208-T-C	BARD1	c.86A>G	p.D29G	Missense	1/11	-
15-93489062-A-G	CHD2	c.1165A>G	p.S389G	Missense	11/39	-
2-212288922-G-T	ERBB4	c.2824C>A	p.P942T	Missense	23/28	-
2-239179991-G-A	PER2	c.734C>T	p.P245L	Missense	6/23	-
17-40485751-G-T	STAT3	c.989C>A	p.P330H	Missense	10/24	-
16-23647469-C-T	PALB2	c.398G>A	p.S133N	Missense	4/13	-
2-141264407-C-G	LRP1B	c.8479G>C	p.D2827H	Missense	53/91	-
18-51820472-G-T	POLI	c.1858G>T	p.D620Y	Missense	10/10	-
5-23527554-G-T	PRDM9	c.2357G>T	p.R786I	Missense	11/11	-
3-142277550-A-G	ATR	c.1801T>C	p.S601P	Missense	8/47	-
2-212522495-A-T	ERBB4	c.1930T>A	p.L644I	Missense	16/28	-
11-118377252-C-T	KMT2A	c.10645C>T	p.P3549S	Missense	27/36	-
2-141081542-T-C	LRP1B	c.12434A>G	p.H4145R	Missense	81/91	-
4-2209818-C-A	POLN	c.610G>T	p.D204Y	Missense	5/26	-
8-92982932-G-T	RUNX1T1	c.1382C>A	p.A461E	Missense	10/11	-
3-47147560-A-C	SETD2	c.4766T>G	p.F1589C	Missense	6/21	-
2-39249768-T-A	SOS1	c.1801A>T	p.I601F	Missense	10/23	-
5-1295047-C-A	TERT	c.58G>T	p.E20*	Nonsense	1/16	-
1-150795793-G-A	ARNT	c.1271C>T	p.S424F	Missense	14/22	-
X-76953101-G-C	ATRX	c.212C>G	p.S71C	Missense	4/35	-
X-76953110-G-A	ATRX	c.203C>T	p.S68L	Missense	4/35	-
3-52436654-A-G	BAP1	c.2020T>C	p.F674L	Missense	16/17	-
5-11385202-GC-TT	CTNND2	c.751_752delinsAA	p.A251K	Missense	7/22	-
5-149497256-T-C	PDGFRB	c.3062A>G	p.Y1021C	Missense	22/23	-
14-99641988-G-C	BCL11B	c.1185C>G	p.F395L	Missense	4/4	-
14-35231418-C-A	BAZ1A	c.3788G>T	p.R1263L	Missense	24/27	-
12-46246251-A-C	ARID2	c.4345A>C	p.N1449H	Missense	15/21	-
14-35269537-C-T	BAZ1A	c.1021G>A	p.E341K	Missense	9/27	-
7-2972181-A-C	CARD11	c.1558T>G	p.S520A	Missense	11/25	-
5-11385122-T-G	CTNND2	c.832A>C	p.T278P	Missense	7/22	-
3-89499462-C-G	EPHA3	c.2632C>G	p.L878V	Missense	15/17	-
8-139263241-C-A	FAM135B	c.385G>T	p.G129W	Missense	6/20	-
4-187628332-C-A	FAT1	c.2650G>T	p.D884Y	Missense	2/27	-
2-140997050-G-T	LRP1B	c.13376C>A	p.T4459N	Missense	88/91	-
2-141135814-C-A	LRP1B	c.10573G>T	p.G3525W	Missense	68/91	-
2-141202233-T-A	LRP1B	c.10073A>T	p.Q3358L	Missense	64/91	-
11-77070009-C-A	PAK1	c.531G>T	p.E177D	Missense	6/15	-
13-67801530-A-C	PCDH9	c.1043T>G	p.V348G	Missense	2/5	-
4-55141080-G-T	PDGFRA	c.1726G>T	p.D576Y	Missense	12/23	-
8-139151306-C-G	FAM135B	c.3824G>C	p.G1275A	Missense	18/20	-
16-89825054-C-A	FANCA	c.2912G>T	p.G971V	Missense	30/43	-
1-91850744-G-C	HFM1	c.802C>G	p.P268A	Missense	6/39	-
19-15288896-G-C	NOTCH3	c.3843C>G	p.F1281L	Missense	24/33	-
17-58678138-G-A	PPM1D	c.363G>A	p.W121*	Nonsense	1/6	-
17-78899251-G-A	RPTOR	c.2890G>A	p.A964T	Missense	24/34	-
4-25678223-G-C	SLC34A2	c.1925G>C	p.S642T	Missense	13/13	-
11-114113017-C-G	ZBTB16	c.1582C>G	p.P528A	Missense	5/7	-
20-52192857-T-A	ZNF217	c.2446A>T	p.S816C	Missense	4/6	-
16-2108815-G-A	TSC2	c.916G>A	p.A306T	Missense	10/42	-
5-23522845-G-T	PRDM9	c.733G>T	p.G245W	Missense	8/11	-
7-55231493-A-G	EGFR	c.1699A>G	p.M567V	Missense	14/28	-
16-23619314-A-C	PALB2	c.3221T>G	p.L1074R	Missense	12/13	-
3-121155065-T-C	POLQ	c.7447A>G	p.I2483V	Missense	28/30	-
4-25678205-CCAAGTGCTGCCGCTGCAG-C	SLC34A2	c.1918_1935del18	p.R640_C645del	InFrameDeletion	13/13	-
2-212248520-AGGTG-TT	ERBB4	c.3743_3747delinsAA	p.P1248_P1249delinsQ	MultiAAMissense	28/28	-
16-89833592-C-A	FANCA	c.2558G>T	p.R853L	Missense	27/43	-
8-139277959-A-G	FAM135B	c.284T>C	p.L95S	Missense	4/20	-
15-40913801-A-G	KNL1	c.1339A>G	p.R447G	Missense	10/26	-
9-139413132-T-A	NOTCH1	c.1010A>T	p.D337V	Missense	6/34	-
12-57597239-G-A	LRP1	c.10886G>A	p.R3629H	Missense	70/89	-
7-81372740-C-A	HGF	c.794G>T	p.G265V	Missense	7/18	-
12-49426825-T-C	KMT2D	c.11663A>G	p.K3888R	Missense	40/55	-
12-49440509-C-T	KMT2D	c.4301G>A	p.G1434D	Missense	16/55	-
12-57595318-A-G	LRP1	c.10384A>G	p.I3462V	Missense	66/89	-
21-36171619-C-A	RUNX1	c.946G>T	p.E316*	Nonsense	8/9	-
12-57563051-G-T	LRP1	c.3124G>T	p.D1042Y	Missense	20/89	-
1-120496231-T-G	NOTCH2	c.2300A>C	p.Q767P	Missense	14/34	-
12-57532324-G-T	LRP1	c.150G>T	p.E50D	Missense	2/89	-
18-48584742-TGCA-T	SMAD4	c.820_822delGCA	p.A274del	InFrameDeletion	7/12	-
12-49436049-C-A	KMT2D	c.5932G>T	p.G1978C	Missense	29/55	-
12-57604261-C-G	LRP1	c.12752C>G	p.S4251C	Missense	82/89	-
12-49434696-T-A	KMT2D	c.6857A>T	p.E2286V	Missense	32/55	-
9-2029224-G-T	SMARCA2	c.202G>T	p.E68*	Nonsense	2/34	-
12-49443517-T-C	KMT2D	c.3854A>G	p.E1285G	Missense	12/55	-
X-70356467-A-C	MED12	c.5362A>C	p.K1788Q	Missense	37/45	-
X-70348526-G-T	MED12	c.3433G>T	p.D1145Y	Missense	24/45	-
X-70361791-G-T	MED12	c.6467G>T	p.R2156L	Missense	44/45	-
1-120478167-G-C	NOTCH2	c.3583C>G	p.P1195A	Missense	22/34	-
16-9916155-C-T	GRIN2A	c.2134G>A	p.G712R	Missense	10/13	-
9-2047283-C-T	SMARCA2	c.845C>T	p.A282V	Missense	5/34	-
12-49440462-T-A	KMT2D	c.4348A>T	p.I1450F	Missense	16/55	-
1-120459145-A-T	NOTCH2	c.6200T>A	p.V2067E	Missense	34/34	-
16-9862936-C-G	GRIN2A	c.2367G>C	p.E789D	Missense	12/13	-
16-9862936-C-A	GRIN2A	c.2367G>T	p.E789D	Missense	12/13	-
9-2039818-ACAGCAG-A	SMARCA2	c.710_715delAGCAGC	p.Q237_Q238del	InFrameDeletion	4/34	-
12-115120657-G-C	TBX3	c.349C>G	p.H117D	Missense	1/7	-
12-49416391-C-G	KMT2D	c.16320G>C	p.E5440D	Missense	52/55	-
6-94129004-A-C	EPHA7	c.56T>G	p.L19R	Missense	1/17	-
7-81392035-G-T	HGF	c.242C>A	p.P81Q	Missense	2/18	-
7-81392186-C-A	HGF	c.91G>T	p.G31*	Nonsense	2/18	-
12-115112024-CCC-GCT	TBX3	c.1654_1656delGGGinsAGC	p.G552S	Missense	6/7	-
16-3817899-C-G	CREBBP	c.3072G>C	p.E1024D	Missense	16/31	-
16-3817899-C-A	CREBBP	c.3072G>T	p.E1024D	Missense	16/31	-
4-187538244-G-A	FAT1	c.8990C>T	p.T2997M	Missense	11/27	-
13-110435960-T-C	IRS2	c.2441A>G	p.Y814C	Missense	1/2	-
4-187628631-G-A	FAT1	c.2351C>T	p.T784I	Missense	2/27	-
8-128753080-C-A	MYC	c.1241C>A	p.A414D	Missense	3/3	-
13-110437863-C-A	IRS2	c.538G>T	p.A180S	Missense	1/2	-
4-187629658-C-T	FAT1	c.1324G>A	p.D442N	Missense	2/27	-
X-70680558-G-C	TAF1	c.5364G>C	p.E1768D	Missense	37/38	-
X-70680558-G-T	TAF1	c.5304G>T	p.E1768D	Missense	37/38	-
13-110438117-A-G	IRS2	c.284T>C	p.L95P	Missense	1/2	-
4-187532548-G-C	FAT1	c.9845C>G	p.S3282C	Missense	14/27	-
1-16256699-G-C	SPEN	c.3964G>C	p.D1322H	Missense	11/15	-
1-16261949-C-G	SPEN	c.9214C>G	p.H3072D	Missense	11/15	-
4-187538923-G-C	FAT1	c.8817C>G	p.I2939M	Missense	10/27	-
3-52584798-T-C	PBRM1	c.4324A>G	p.T1442A	Missense	28/30	-
4-187525680-C-A	FAT1	c.10399G>T	p.E3467*	Nonsense	18/27	-
8-68981319-A-G	PREX2	c.1391A>G	p.Y464C	Missense	12/40	-
3-47164304-C-A	SETD2	c.1822G>T	p.E608*	Nonsense	3/21	-
8-68942774-G-T	PREX2	c.586G>T	p.A196S	Missense	6/40	-
X-70357781-CC-TG	MED12	c.6032_6033delCCinsTG	p.T2011M	Missense	41/45	-
3-47125724-G-C	SETD2	c.5546C>G	p.S1849W	Missense	12/21	-
5-38949917-A-C	RICTOR	c.4033T>G	p.L1345V	Missense	31/38	-
3-47165651-T-A	SETD2	c.475A>T	p.T159S	Missense	3/21	-
2-178098984-C-A	NFE2L2	c.61G>T	p.D21Y	Missense	2/5	-
18-48584506-A-G	SMAD4	c.679A>G	p.S227G	Missense	6/12	-
12-49446748-TCC-ACA	KMT2D	c.1060_1062delGGAinsTGT	p.G354C	Missense	9/55	-
5-11110975-C-T	CTNND2	c.2458G>A	p.D820N	Missense	14/22	-
4-20543124-G-T	SLIT2	c.2025G>T	p.L675F	Missense	20/37	-
5-11236868-C-A	CTNND2	c.1696G>T	p.V566F	Missense	10/22	-
19-15280908-T-A	NOTCH3	c.5188A>T	p.K1730*	Nonsense	28/33	-
4-175898075-T-C	ADAM29	c.1399T>C	p.W467R	Missense	5/5	-
11-118376225-G-C	KMT2A	c.9618G>C	p.Q3206H	Missense	27/36	-
17-63554240-C-T	AXIN2	c.499G>A	p.D167N	Missense	2/11	-
11-125513786-G-C	CHEK1	c.914G>C	p.S305T	Missense	9/13	-
5-176524364-C-G	FGFR4	c.2225C>G	p.A742G	Missense	17/18	-
4-20618628-A-T	SLIT2	c.3943A>T	p.S1315C	Missense	35/37	-
19-15291035-C-A	NOTCH3	c.3175G>T	p.G1059W	Missense	20/33	-
22-24145525-C-G	SMARCB1	c.544C>G	p.Q182E	Missense	5/9	-
5-176522723-A-G	FGFR4	c.1820A>G	p.K607R	Missense	13/18	-
8-139190903-G-C	FAM135B	c.904C>G	p.Q302E	Missense	10/20	-
18-48575674-G-T	SMAD4	c.434G>T	p.G145V	Missense	4/12	-
X-39932554-T-A	BCOR	c.2045A>T	p.H682L	Missense	4/15	-
18-18546966-C-G	ROCK1	c.3264G>C	p.E1088D	Missense	27/33	-
19-10472789-T-A	TYK2	c.1738A>T	p.S580C	Missense	12/25	-
18-18572812-T-A	ROCK1	c.1972A>T	p.M658L	Missense	17/33	-
8-139163888-C-A	FAM135B	c.2830G>T	p.D944Y	Missense	13/20	-
19-10476399-G-A	TYK2	c.805C>T	p.R269C	Missense	7/25	-
13-28622559-G-C	FLT3	c.1058C>G	p.T353S	Missense	9/24	-
19-10464256-C-A	TYK2	c.2975G>T	p.R992L	Missense	21/25	-
6-93956531-G-C	EPHA7	c.2705C>G	p.T902S	Missense	15/17	-
18-18566917-C-G	ROCK1	c.2298G>C	p.E766D	Missense	19/33	-
8-139209873-C-G	FAM135B	c.709G>C	p.A237P	Missense	8/20	-
8-37556173-C-T	ZNF703	c.1754C>T	p.S585L	Missense	2/2	-
8-37691596-G-T	ADGRA2	c.1558G>T	p.E520*	Nonsense	11/19	-
18-18534990-C-A	ROCK1	c.3607G>T	p.E1203*	Nonsense	31/33	-
8-37555705-C-T	ZNF703	c.1286C>T	p.S429L	Missense	2/2	-
4-175897489-G-T	ADAM29	c.813G>T	p.K271N	Missense	5/5	-
8-139163887-T-A	FAM135B	c.2831A>T	p.D944V	Missense	13/20	-
8-37695353-G-C	ADGRA2	c.2155G>C	p.G719R	Missense	14/19	-
13-28588656-C-A	FLT3	c.2792G>T	p.R931M	Missense	23/24	-
8-37553534-C-T	ZNF703	c.37C>T	p.P13S	Missense	1/2	-
8-37697739-C-A	ADGRA2	c.2612C>A	p.P871Q	Missense	17/19	-
18-18586366-C-T	ROCK1	c.1831G>A	p.E611K	Missense	16/33	-
12-46211469-T-G	ARID2	c.435T>G	p.S145R	Missense	5/21	-
8-37692903-C-A	ADGRA2	c.1820C>A	p.S607Y	Missense	12/19	-
8-37691236-C-A	ADGRA2	c.1327C>A	p.L443M	Missense	10/19	-
9-139412386-G-A	NOTCH1	c.1259C>T	p.A420V	Missense	8/34	-
X-47030454-G-C	RBM10	c.229G>C	p.E77Q	Missense	4/24	-
12-46211464-C-G	ARID2	c.430C>G	p.Q144E	Missense	5/21	-
8-37698298-G-A	ADGRA2	c.2678G>A	p.G893E	Missense	18/19	-
10-104268958-G-T	SUFU	c.215G>T	p.S72I	Missense	2/12	-
12-46287426-G-T	ARID2	c.5285G>T	p.G1762V	Missense	20/21	-
8-139190879-G-A	FAM135B	c.928C>T	p.L310F	Missense	10/20	-
8-37692736-C-A	ADGRA2	c.1653C>A	p.H551Q	Missense	12/19	-
X-47039636-T-G	RBM10	c.1088T>G	p.L363R	Missense	11/24	-
3-52439804-G-A	BAP1	c.908C>T	p.A303V	Missense	10/17	-
5-39003717-C-A	RICTOR	c.203G>T	p.C68F	Missense	4/38	-
19-10599875-G-T	KEAP1	c.1701C>A	p.Y567*	Nonsense	5/6	-
17-33446587-T-C	RAD51D	c.46A>G	p.M16V	Missense	1/10	-
X-76937030-C-T	ATRX	c.3718G>A	p.G1240R	Missense	9/35	-
4-20555511-G-T	SLIT2	c.2645G>T	p.G882V	Missense	26/37	-
19-10610409-C-T	KEAP1	c.301G>A	p.A101T	Missense	2/6	-
X-76938270-C-A	ATRX	c.2478G>T	p.K826N	Missense	9/35	-
19-10599891-T-G	KEAP1	c.1685A>C	p.H562P	Missense	5/6	-
3-169998165-A-G	PRKCI	c.856A>G	p.K286E	Missense	9/18	-
12-57554704-G-T	LRP1	c.2008G>T	p.D670Y	Missense	13/89	-
12-49424527-C-T	KMT2D	c.13696G>A	p.E4566K	Missense	42/55	-
4-20490482-G-A	SLIT2	c.652G>A	p.A218T	Missense	8/37	-
19-15311712-C-A	NOTCH3	c.5G>T	p.G2V	Missense	1/33	-
5-11159777-G-T	CTNND2	c.2070C>A	p.H690Q	Missense	12/22	-
19-15288753-C-A	NOTCH3	c.3986G>T	p.G1329V	Missense	24/33	-
12-57859571-G-T	GLI1	c.625G>T	p.D209Y	Missense	7/12	-
2-25470018-C-G	DNMT3A	c.1024G>C	p.E342Q	Missense	9/23	-
7-128845620-C-T	SMO	c.917C>T	p.P306L	Missense	4/12	-
7-151884466-G-T	KMT2C	c.4889C>A	p.S1630*	Nonsense	33/59	-
1-120508086-C-A	NOTCH2	c.1671G>T	p.Q557H	Missense	10/34	-
1-120508086-C-G	NOTCH2	c.1671G>C	p.Q557H	Missense	10/34	-
4-20525800-G-T	SLIT2	c.1438G>T	p.A480S	Missense	14/37	-
7-151859914-G-A	KMT2C	c.10748C>T	p.P3583L	Missense	43/59	-
19-15297773-C-T	NOTCH3	c.1867G>A	p.D623N	Missense	12/33	-
X-70603983-CGG-TGT	TAF1	c.2179_2181delCGGinsTGT	p.R707C	Missense	13/38	-
7-151859998-G-C	KMT2C	c.10664C>G	p.P3555R	Missense	43/59	-
4-175898672-C-A	ADAM29	c.1996C>A	p.P666T	Missense	5/5	-
12-57864752-T-A	GLI1	c.2229T>A	p.Y743*	Nonsense	12/12	-
2-25536819-G-C	DNMT3A	c.35C>G	p.T12S	Missense	2/23	-
22-41562638-GAACTAGGAAAGAAAATAAGTTTTCTGCTAA-G	EP300	c.3845_3874del30	p.T1282_K1291del	InFrameDeletion	23/31	-
7-81334798-C-T	HGF	c.1918G>A	p.E640K	Missense	17/18	-
7-81392087-C-A	HGF	c.190G>T	p.V64L	Missense	2/18	-
15-40913801-AGA-TGT	KNL1	c.1339_1341delAGAinsTGT	p.R447C	Missense	10/26	-
7-81358958-G-A	HGF	c.1003C>T	p.H335Y	Missense	8/18	-
7-151859879-C-A	KMT2C	c.10783G>T	p.D3595Y	Missense	43/59	-
7-151900080-AT-TA	KMT2C	c.4030_4031delATinsTA	p.I1344*	Nonsense	26/59	-
4-175898849-C-G	ADAM29	c.2173C>G	p.P725A	Missense	5/5	-
4-20620609-G-T	SLIT2	c.4567G>T	p.G1523C	Missense	37/37	-
7-152132792-G-T	KMT2C	c.80C>A	p.P27Q	Missense	1/59	-
7-151874130-G-A	KMT2C	c.8408C>T	p.T2803I	Missense	38/59	-
5-35873598-G-T	IL7R	c.554G>T	p.S185I	Missense	5/8	-
7-151874552-C-A	KMT2C	c.7986G>T	p.L2662F	Missense	38/59	-
6-93964429-C-A	EPHA7	c.2468G>T	p.G823V	Missense	14/17	-
5-56161261-G-C	MAP3K1	c.1130G>C	p.R377T	Missense	5/20	-
4-143045777-C-G	INPP4B	c.1857G>C	p.M619I	Missense	19/26	-
4-143045777-C-T	INPP4B	c.1857G>A	p.M619I	Missense	19/26	-
2-25497834-C-A	DNMT3A	c.615G>T	p.E205D	Missense	6/23	-
1-120458487-G-T	NOTCH2	c.6858C>A	p.S2286R	Missense	34/34	-
5-176520497-G-C	FGFR4	c.1342G>C	p.G448R	Missense	10/18	-
13-110437074-T-A	IRS2	c.1327A>T	p.T443S	Missense	1/2	-
12-49438220-T-G	KMT2D	c.5049A>C	p.E1683D	Missense	21/55	-
1-120468106-T-C	NOTCH2	c.4333A>G	p.S1445G	Missense	25/34	-
13-110436394-G-T	IRS2	c.2007C>A	p.S669R	Missense	1/2	-
4-187534455-C-T	FAT1	c.9271G>A	p.A3091T	Missense	13/27	-
16-3781436-G-C	CREBBP	c.4929C>G	p.I1643M	Missense	30/31	-
7-2968281-C-A	CARD11	c.1705G>T	p.G569*	Nonsense	13/25	-
X-53250025-A-G	KDM5C	c.224T>C	p.L75P	Missense	2/26	-
7-2946391-G-T	CARD11	c.3346C>A	p.L1116M	Missense	25/25	-
9-139403394-GCC-TCA	NOTCH1	c.3097_3099delGGCinsTGA	p.G1033*	Nonsense	19/34	-
8-32599551-AGA-TGT	NRG1	c.658_660delAGAinsTGT	p.R220C	Missense	7/12	-
17-37627532-T-A	CDK12	c.1447T>A	p.L483M	Missense	2/14	-
19-10463759-G-T	TYK2	c.3043C>A	p.H1015N	Missense	22/25	-
5-149509464-T-A	PDGFRB	c.1435A>T	p.N479Y	Missense	10/23	-
5-149499610-G-A	PDGFRB	c.2663C>T	p.S888F	Missense	19/23	-
5-149497221-C-A	PDGFRB	c.3097G>T	p.A1033S	Missense	22/23	-
5-149513212-A-T	PDGFRB	c.871T>A	p.C291S	Missense	6/23	-
16-3860727-TC-GT	CREBBP	c.851_852delGAinsAC	p.G284D	Missense	3/31	-
7-151927330-CT-TA	KMT2C	c.2845_2846delAGinsTA	p.S949Y	Missense	17/59	-
11-69625357-G-T	FGF3	c.436C>A	p.Q146K	Missense	3/3	-
11-69625098-G-T	FGF3	c.695C>A	p.S232Y	Missense	3/3	-
12-49426896-GTGC-G	KMT2D	c.11589_11591delGCA	p.Q3863del	InFrameDeletion	40/55	-
12-57556673-G-C	LRP1	c.2437G>C	p.G813R	Missense	15/89	-
10-123239409-G-A	FGFR2	c.2428C>T	p.P810S	Missense	18/18	-
X-47040785-G-C	RBM10	c.1420G>C	p.D474H	Missense	13/24	-
8-139180227-G-T	FAM135B	c.1169C>A	p.P390Q	Missense	12/20	-
10-50732610-C-A	ERCC6	c.866G>T	p.G289V	Missense	5/21	-
10-84744859-C-A	NRG3	c.1589C>A	p.S530*	Nonsense	9/9	-
22-41489055-C-T	EP300	c.47C>T	p.P16L	Missense	1/31	-
19-17945402-G-T	JAK3	c.2328C>A	p.D776E	Missense	17/24	-
12-49445232-G-A	KMT2D	c.2234C>T	p.P745L	Missense	11/55	-
X-53241049-C-A	KDM5C	c.1162G>T	p.A388S	Missense	9/26	-
12-49444773-G-A	KMT2D	c.2693C>T	p.P898L	Missense	11/55	-
X-53231139-T-A	KDM5C	c.1763A>T	p.Q588L	Missense	13/26	-
1-120493406-T-G	NOTCH2	c.2420A>C	p.Q807P	Missense	15/34	-
10-123279680-CG-TT	FGFR2	c.751_752delCGinsAA	p.R251K	Missense	7/18	-
2-212426675-T-A	ERBB4	c.2440A>T	p.N814Y	Missense	20/28	-
16-3900312-C-A	CREBBP	c.784G>T	p.G262*	Nonsense	2/31	-
7-142655047-C-A	KEL	c.539G>T	p.R180L	Missense	6/19	-
22-21346032-G-T	LZTR1	c.907G>T	p.A303S	Missense	9/21	-
16-3778547-C-A	CREBBP	c.6501G>T	p.Q2167H	Missense	31/31	-
10-43609030-C-A	RET	c.1786C>A	p.P596T	Missense	10/20	-
20-43955990-G-C	SDC4	c.511C>G	p.R171G	Missense	5/5	-
18-42530347-C-G	SETBP1	c.1042C>G	p.P348A	Missense	4/6	-
1-158582725-T-C	SPTA1	c.7016A>G	p.Y2339C	Missense	51/52	-
X-123211817-A-G	STAG2	c.2684A>G	p.D895G	Missense	27/35	-
16-23652457-G-A	PALB2	c.22C>T	p.P8S	Missense	1/13	-
17-63554302-G-C	AXIN2	c.437C>G	p.S146C	Missense	2/11	-
1-7700542-C-A	CAMTA1	c.593C>A	p.S198Y	Missense	7/23	-
5-24537497-G-T	CDH10	c.518C>A	p.S173Y	Missense	3/12	-
3-48627067-G-C	COL7A1	c.2135C>G	p.A712G	Missense	17/119	-
5-11236878-C-A	CTNND2	c.1686G>T	p.Q562H	Missense	10/22	-
13-73346015-T-A	DIS3	c.1523A>T	p.D508V	Missense	11/21	-
X-37028800-C-T	FAM47C	c.2317C>T	p.H773Y	Missense	1/1	-
X-37027138-G-T	FAM47C	c.655G>T	p.V219L	Missense	1/1	-
5-180048726-G-C	FLT4	c.1836C>G	p.N612K	Missense	13/30	-
6-114270369-C-A	HDAC2	c.695G>T	p.G232V	Missense	7/14	-
7-26233300-C-G	HNRNPA2B1	c.736G>C	p.G246R	Missense	8/11	-
7-151874299-C-T	KMT2C	c.8239G>A	p.D2747N	Missense	38/59	-
1-32741261-G-C	LCK	c.469G>C	p.E157Q	Missense	6/13	-
15-41991349-T-G	MGA	c.2180T>G	p.L727R	Missense	5/24	-
1-76356413-A-T	MSH4	c.2259A>T	p.K753N	Missense	17/20	-
5-38955701-G-A	RICTOR	c.2605C>T	p.Q869*	Nonsense	26/38	-
1-205632093-C-A	SLC45A3	c.826G>T	p.V276L	Missense	3/5	-
10-70404824-G-A	TET1	c.2338G>A	p.E780K	Missense	4/12	-
12-124862882-C-A	NCOR2	c.2068G>T	p.A690S	Missense	20/49	-
11-108186611-G-A	ATM	c.6068G>A	p.G2023E	Missense	41/63	-
X-63409806-C-T	AMER1	c.3361G>A	p.A1121T	Missense	2/2	-
12-133219531-C-T	POLE	c.4603G>A	p.G1535S	Missense	36/49	-
3-187447397-G-C	BCL6	c.796C>G	p.P266A	Missense	5/10	-
13-26959374-A-C	CDK8	c.541A>C	p.N181H	Missense	6/13	-
1-76363698-C-G	MSH4	c.2462C>G	p.S821*	Nonsense	18/20	-
5-67592046-A-G	PIK3R1	c.1862A>G	p.E621G	Missense	15/16	-
2-55808776-A-G	PPP4R3B	c.1292T>C	p.L431P	Missense	8/17	-
21-36164661-A-G	RUNX1	c.1214T>C	p.L405P	Missense	9/9	-
5-225669-G-T	SDHA	c.448G>T	p.V150L	Missense	4/15	-
8-37554901-C-G	ZNF703	c.482C>G	p.S161C	Missense	2/2	-
17-63531757-G-T	AXIN2	c.2224C>A	p.L742M	Missense	9/11	-
22-29446376-G-A	ZNRF3	c.2207G>A	p.G736E	Missense	8/9	-
13-110438219-G-A	IRS2	c.182C>T	p.T61M	Missense	1/2	-
16-23647463-G-C	PALB2	c.404C>G	p.P135R	Missense	4/13	-
17-78319360-C-T	RNF213	c.7225C>T	p.R2409W	Missense	29/68	-
2-234681071-G-A	UGT1A1	c.1468G>A	p.D490N	Missense	5/5	-
5-23523463-A-T	PRDM9	c.946A>T	p.M316L	Missense	9/11	-
21-44513330-C-T	U2AF1	c.605G>A	p.R202H	Missense	8/8	-
X-14883336-A-T	FANCB	c.297T>A	p.N99K	Missense	3/10	-
2-141660704-C-A	LRP1B	c.3551G>T	p.S1184I	Missense	23/91	-
2-141474278-C-A	LRP1B	c.5866G>T	p.E1956*	Nonsense	36/91	-
6-116381131-G-C	FRK	c.344C>G	p.P115R	Missense	1/8	-
6-149997768-C-T	LATS1	c.2699G>A	p.R900H	Missense	6/8	-
1-202302426-A-G	UBE2T	c.323T>C	p.L108S	Missense	5/7	-
16-23646821-T-G	PALB2	c.1046A>C	p.N349T	Missense	4/13	-
19-10912992-C-T	DNM2	c.1451C>T	p.S484F	Missense	12/21	-
12-49425664-T-C	KMT2D	c.12824A>G	p.Q4275R	Missense	40/55	-
9-139404390-A-C	NOTCH1	c.2764T>G	p.C922G	Missense	18/34	-
7-42188037-C-G	GLI3	c.155G>C	p.R52T	Missense	3/15	-
4-143130087-A-G	INPP4B	c.929T>C	p.M310T	Missense	13/26	-
4-143094901-T-C	INPP4B	c.1243A>G	p.S415G	Missense	16/26	-
7-42004731-T-C	GLI3	c.3940A>G	p.N1314D	Missense	15/15	-
9-139417446-C-A	NOTCH1	c.598G>T	p.G200C	Missense	4/34	-
5-180056747-C-T	FLT4	c.765G>A	p.W255*	Nonsense	6/30	-
9-139390766-GGG-TTA	NOTCH1	c.7423_7425delCCCinsTAA	p.P2475*	Nonsense	34/34	-
9-139392007-C-A	NOTCH1	c.6184G>T	p.E2062*	Nonsense	34/34	-
10-8097853-C-A	GATA3	c.235C>A	p.H79N	Missense	2/6	-
10-84718751-G-T	NRG3	c.1204G>T	p.G402C	Missense	6/9	-
10-84738875-G-T	NRG3	c.1582G>T	p.G528W	Missense	8/9	-
10-84118519-G-C	NRG3	c.848G>C	p.R283P	Missense	2/9	-
2-141460009-G-T	LRP1B	c.6137C>A	p.S2046Y	Missense	38/91	-
16-23646565-A-T	PALB2	c.1302T>A	p.D434E	Missense	4/13	-
4-55153666-G-A	PDGFRA	c.2632G>A	p.V878I	Missense	19/23	-
14-68292278-C-T	RAD51B	c.182C>T	p.A61V	Missense	3/11	-
1-155874203-C-T	RIT1	c.328G>A	p.E110K	Missense	5/6	-
7-101870899-C-G	CUX1	c.3383C>G	p.T1128S	Missense	21/24	-
5-38511972-T-A	LIFR	c.656A>T	p.E219V	Missense	6/20	-
6-30680806-C-T	MDC1	c.913G>A	p.D305N	Missense	5/15	-
6-30680838-G-A	MDC1	c.881C>T	p.P294L	Missense	5/15	-
1-11199643-C-G	MTOR	c.4945G>C	p.D1649H	Missense	35/58	-
16-23649272-C-G	PALB2	c.110G>C	p.R37P	Missense	3/13	-
4-41748126-C-A	PHOX2B	c.643G>T	p.G215C	Missense	3/3	-
15-89876714-C-A	POLG	c.272G>T	p.G91V	Missense	2/23	-
4-39303945-C-A	RFC1	c.2488G>T	p.D830Y	Missense	19/25	-
17-56435723-G-A	RNF43	c.1414C>T	p.H472Y	Missense	9/10	-
12-111856316-G-A	SH2B3	c.367G>A	p.E123K	Missense	2/8	-
10-70446125-A-G	TET1	c.5065A>G	p.T1689A	Missense	11/12	-
11-114118018-G-T	ZBTB16	c.1723G>T	p.E575*	Nonsense	6/7	-
12-6711147-CTCC-A	CHD4	c.414_417delinsT	p.E138_E139delinsD	MultiAAMissense	4/40	-
10-70332496-T-G	TET1	c.401T>G	p.L134*	Nonsense	2/12	-
20-52198485-G-A	ZNF217	c.881C>T	p.T294I	Missense	2/6	-
X-47429381-G-C	ARAF	c.1509G>C	p.M503I	Missense	14/16	-
19-11169036-A-G	SMARCA4	c.4530A>G	p.I1510M	Missense	31/35	-
15-93496744-A-T	CHD2	c.1660A>T	p.I554F	Missense	14/39	-
2-212293169-T-A	ERBB4	c.2683A>T	p.R895W	Missense	22/28	-
6-32178654-A-T	NOTCH4	c.2740T>A	p.Y914N	Missense	18/30	-
16-81954854-A-C	PLCG2	c.2287A>C	p.S763R	Missense	21/33	-
3-48461153-C-A	PLXNB1	c.2542G>T	p.E848*	Nonsense	11/38	-
7-128845484-C-A	SMO	c.781C>A	p.R261S	Missense	4/12	-
1-158609732-C-A	SPTA1	c.4803G>T	p.K1601N	Missense	34/52	-
19-1625692-C-A	TCF3	c.382G>T	p.G128C	Missense	7/19	-
15-91358420-A-G	BLM	c.4165A>G	p.T1389A	Missense	22/22	-
16-65016047-G-A	CDH11	c.1157C>T	p.P386L	Missense	8/13	-
20-52193049-G-C	ZNF217	c.2254C>G	p.R752G	Missense	4/6	-
7-50358659-T-C	IKZF1	c.2T>C	p.M1?	Missense	2/8	-
X-47429381-G-A	ARAF	c.1509G>A	p.M503I	Missense	14/16	-
3-48607342-G-A	COL7A1	c.7492C>T	p.P2498S	Missense	100/119	-
7-86468735-G-T	GRM3	c.1905G>T	p.K635N	Missense	4/6	-
2-225371637-C-A	CUL3	c.967G>T	p.E323*	Nonsense	7/16	-
18-45371774-T-C	SMAD2	c.1217A>G	p.Y406C	Missense	10/11	-
1-162748394-G-C	DDR2	c.2308G>C	p.V770L	Missense	17/18	-
1-162748394-G-T	DDR2	c.2308G>T	p.V770L	Missense	17/18	-
18-45423039-C-A	SMAD2	c.89G>T	p.G30V	Missense	2/11	-
17-12011167-G-T	MAP2K4	c.574G>T	p.V192L	Missense	5/11	-
1-162729641-A-T	DDR2	c.727A>T	p.T243S	Missense	8/18	-
X-123220540-G-T	STAG2	c.3197G>T	p.R1066L	Missense	30/35	-
12-4553305-G-T	FGF6	c.444C>A	p.Y148*	Nonsense	2/3	-
7-77756609-G-T	MAGI2	c.3328C>A	p.P1110T	Missense	19/22	-
4-110932446-T-A	EGF	c.3459T>A	p.D1153E	Missense	24/24	-
12-4553336-A-C	FGF6	c.413T>G	p.F138C	Missense	2/3	-
7-77824343-G-T	MAGI2	c.2117C>A	p.T706K	Missense	12/22	-
17-40491385-C-A	STAT3	c.415G>T	p.E139*	Nonsense	5/24	-
17-40490753-T-A	STAT3	c.546A>T	p.Q182H	Missense	6/24	-
7-77764475-C-T	MAGI2	c.2894G>A	p.R965H	Missense	17/22	-
5-44305164-C-A	FGF10	c.560G>T	p.R187M	Missense	3/3	-
9-27158068-G-A	TEK	c.292G>A	p.G98S	Missense	2/23	-
8-56922564-G-A	LYN	c.1434G>A	p.M478I	Missense	13/13	-
3-138665311-A-C	FOXL2	c.254T>G	p.I85S	Missense	1/1	-
3-138665021-C-A	FOXL2	c.544G>T	p.G182W	Missense	1/1	-
6-35420392-G-C	FANCE	c.70G>C	p.A24P	Missense	1/10	-
18-19751266-C-T	GATA6	c.161C>T	p.P54L	Missense	2/7	-
18-19751928-G-T	GATA6	c.823G>T	p.A275S	Missense	2/7	-
9-101908791-T-G	TGFBR1	c.1155T>G	p.D385E	Missense	7/9	-
9-101908791-T-A	TGFBR1	c.1155T>A	p.D385E	Missense	7/9	-
1-43806095-G-C	MPL	c.891G>C	p.K297N	Missense	6/12	-
1-32745537-G-C	LCK	c.1137G>C	p.K379N	Missense	11/13	-
2-109365402-G-T	RANBP2	c.1090G>T	p.G364C	Missense	9/29	-
2-109381431-A-G	RANBP2	c.4436A>G	p.K1479R	Missense	20/29	-
1-92944298-C-G	GFI1	c.937G>C	p.D313H	Missense	6/7	-
14-50904199-C-G	MAP4K5	c.1877G>C	p.C626S	Missense	26/33	-
X-47429381-G-T	ARAF	c.1509G>T	p.M503I	Missense	14/16	-
16-72822008-TTGCTGCTGCTGCTGCTGTAGTTGCCGC-T	ZFHX3	c.10140_10166del27	p.R3381_Q3389del	InFrameDeletion	10/10	-
5-176636733-G-A	NSD1	c.1333G>A	p.G445S	Missense	5/23	-
9-101910019-G-C	TGFBR1	c.1339G>C	p.E447Q	Missense	8/9	-
X-37029167-C-A	FAM47C	c.2684C>A	p.S895*	Nonsense	1/1	-
16-14038647-AG-CA	ERCC4	c.1972_1973delAGinsCA	p.R658Q	Missense	10/11	-
7-50367270-A-T	IKZF1	c.77A>T	p.E26V	Missense	3/8	-
13-43148645-A-G	TNFSF11	c.206A>G	p.Y69C	Missense	1/5	-
12-394642-C-A	KDM5A	c.5053G>T	p.D1685Y	Missense	28/28	-
12-432880-C-A	KDM5A	c.2036G>T	p.C679F	Missense	15/28	-
14-35873801-C-G	NFKBIA	c.50G>C	p.R17P	Missense	1/6	-
8-41838393-C-A	KAT6A	c.878G>T	p.C293F	Missense	5/17	-
17-38561111-C-T	TOP2A	c.1978G>A	p.D660N	Missense	17/35	-
20-52198484-GG-CA	ZNF217	c.881_882delCCinsTG	p.T294M	Missense	2/6	-
5-176638075-C-G	NSD1	c.2675C>G	p.S892C	Missense	5/23	-
15-88680728-G-A	NTRK3	c.529C>T	p.Q177*	Nonsense	7/20	-
5-176721514-C-T	NSD1	c.7145C>T	p.T2382I	Missense	23/23	-
1-243809299-G-C	AKT3	c.325C>G	p.L109V	Missense	5/14	-
3-134670227-T-G	EPHB1	c.138T>G	p.S46R	Missense	3/16	-
3-134670227-T-A	EPHB1	c.138T>A	p.S46R	Missense	3/16	-
3-134670225-A-C	EPHB1	c.136A>C	p.S46R	Missense	3/16	-
11-2156612-G-C	IGF2	c.142C>G	p.R48G	Missense	2/4	-
X-63410306-C-A	AMER1	c.2861G>T	p.G954V	Missense	2/2	-
X-63410076-C-T	AMER1	c.3091G>A	p.G1031S	Missense	2/2	-
16-360032-G-T	AXIN1	c.1057C>A	p.R353S	Missense	4/11	-
13-25073489-G-T	PARP4	c.427C>A	p.P143T	Missense	5/34	-
X-47422679-G-C	ARAF	c.151G>C	p.V51L	Missense	3/16	-
X-47422679-G-T	ARAF	c.151G>T	p.V51L	Missense	3/16	-
15-93557956-G-T	CHD2	c.4723G>T	p.G1575C	Missense	37/39	-
12-6709561-C-A	CHD4	c.1064G>T	p.G355V	Missense	9/40	-
2-42556052-A-T	EML4	c.2368A>T	p.T790S	Missense	22/23	-
12-6711562-T-A	CHD4	c.202A>T	p.S68C	Missense	3/40	-
9-27172646-A-C	TEK	c.661A>C	p.N221H	Missense	5/23	-
3-121215679-G-C	POLQ	c.2254C>G	p.Q752E	Missense	14/30	-
1-36939216-C-G	CSF3R	c.493G>C	p.G165R	Missense	6/17	-
9-133730435-C-A	ABL1	c.501C>A	p.Y167*	Nonsense	3/11	-
9-133730435-C-G	ABL1	c.501C>G	p.Y167*	Nonsense	3/11	-
17-78857240-G-T	RPTOR	c.1606G>T	p.A536S	Missense	15/34	-
3-121192216-C-G	POLQ	c.6524G>C	p.R2175T	Missense	21/30	-
17-78933991-G-T	RPTOR	c.3591G>T	p.M1197I	Missense	30/34	-
1-205589173-G-A	ELK4	c.1001C>T	p.T334M	Missense	3/5	-
17-78899172-TGCGGACGAC-T	RPTOR	c.2820_2828delCGCGGACGA	p.D942_A944del	InFrameDeletion	24/34	-
1-16464859-G-A	EPHA2	c.890C>T	p.T297M	Missense	4/17	-
3-134977916-A-T	EPHB1	c.2909A>T	p.H970L	Missense	16/16	-
19-33792266-T-A	CEBPA	c.1055A>T	p.K352M	Missense	1/1	-
20-62178789-C-A	SRMS	c.28G>T	p.A10S	Missense	1/8	-
3-134884843-C-T	EPHB1	c.1619C>T	p.P540L	Missense	8/16	-
19-18272259-G-A	PIK3R2	c.769G>A	p.A257T	Missense	6/16	-
8-92972640-G-A	RUNX1T1	c.1534C>T	p.H512Y	Missense	11/11	-
4-110862151-T-G	EGF	c.177T>G	p.I59M	Missense	2/24	-
8-56854429-TA-GC	LYN	c.11_12delTAinsGC	p.I4S	Missense	2/13	-
20-52192425-C-A	ZNF217	c.2878G>T	p.V960L	Missense	4/6	-
8-92972597-G-T	RUNX1T1	c.1577C>A	p.T526K	Missense	11/11	-
15-88472559-C-A	NTRK3	c.1996G>T	p.G666C	Missense	17/20	-
5-11385314-C-T	CTNND2	c.640G>A	p.A214T	Missense	7/22	-
3-138456587-C-T	PIK3CB	c.763G>A	p.E255K	Missense	6/24	-
X-47430845-C-A	ARAF	c.1810C>A	p.L604I	Missense	16/16	-
3-138417901-C-T	PIK3CB	c.1618G>A	p.E540K	Missense	13/24	-
20-31022728-G-T	ASXL1	c.2213G>T	p.G738V	Missense	13/13	-
12-56482362-G-T	ERBB3	c.910G>T	p.A304S	Missense	8/28	-
1-193202215-GC-AG	CDC73	c.1247_1248delGCinsAG	p.G416E	Missense	14/17	-
16-396594-G-C	AXIN1	c.432C>G	p.I144M	Missense	2/11	-
15-89876589-C-A	POLG	c.397G>T	p.D133Y	Missense	2/23	-
16-396151-A-T	AXIN1	c.875T>A	p.F292Y	Missense	2/11	-
12-56487933-A-G	ERBB3	c.1664A>G	p.E555G	Missense	14/28	-
19-33793197-G-C	CEBPA	c.124C>G	p.P42A	Missense	1/1	-
17-62007235-C-G	CD79B	c.444G>C	p.L148F	Missense	4/6	-
16-64981840-C-G	CDH11	c.2057G>C	p.G686A	Missense	13/13	-
8-95403872-A-G	RAD54B	c.1774T>C	p.C592R	Missense	10/15	-
5-38963118-A-C	RICTOR	c.1426T>G	p.L476V	Missense	17/38	-
1-158604344-C-G	SPTA1	c.5554G>C	p.A1852P	Missense	39/52	-
16-2131661-A-G	TSC2	c.3676A>G	p.M1226V	Missense	31/42	-
2-216986937-T-C	XRCC5	c.644T>C	p.L215S	Missense	6/21	-
13-110438220-T-C	IRS2	c.181A>G	p.T61A	Missense	1/2	-
12-133240633-A-G	POLE	c.2663T>C	p.V888A	Missense	23/49	-
2-48027925-T-A	MSH6	c.2803T>A	p.S935T	Missense	4/10	-
5-224538-G-T	SDHA	c.214G>T	p.A72S	Missense	3/15	-
9-433928-G-C	DOCK8	c.4839G>C	p.M1613I	Missense	38/48	-
9-5054787-C-G	JAK2	c.839C>G	p.S280*	Nonsense	7/25	-
2-48027797-C-G	MSH6	c.2675C>G	p.S892C	Missense	4/10	-
16-23641322-C-T	PALB2	c.2153G>A	p.R718K	Missense	5/13	-
11-74345631-T-C	POLD3	c.1010T>C	p.F337S	Missense	10/12	-
13-34410346-A-G	RFC3	c.985A>G	p.I329V	Missense	9/9	-
22-38948706-C-T	DMC1	c.386G>A	p.R129H	Missense	7/14	-
4-187629175-G-T	FAT1	c.1807C>A	p.Q603K	Missense	2/27	-
16-10273855-C-G	GRIN2A	c.414G>C	p.K138N	Missense	2/13	-
2-140990810-C-T	LRP1B	c.13745G>A	p.R4582K	Missense	91/91	-
7-40174012-G-A	MPLKIP	c.155C>T	p.P52L	Missense	1/2	-
2-223066810-C-A	PAX3	c.1273G>T	p.V425L	Missense	8/9	-
13-66878831-G-T	PCDH9	c.3670C>A	p.Q1224K	Missense	5/5	-
3-189608666-A-T	TP63	c.1741A>T	p.M581L	Missense	13/14	-
5-98208259-C-A	CHD1	c.3572G>T	p.G1191V	Missense	27/36	-
3-89259367-G-C	EPHA3	c.511G>C	p.V171L	Missense	3/17	-
6-94120474-T-A	EPHA7	c.577A>T	p.I193L	Missense	3/17	-
4-55968146-C-A	KDR	c.2184G>T	p.R728S	Missense	15/30	-
7-128852118-G-T	SMO	c.2190G>T	p.W730C	Missense	12/12	-
16-23625372-C-A	PALB2	c.3154G>T	p.D1052Y	Missense	11/13	-
5-54528344-T-A	CCNO	c.412A>T	p.S138C	Missense	2/3	-
19-42752703-C-A	ERF	c.1561G>T	p.A521S	Missense	4/4	-
3-37070417-C-T	MLH1	c.1552C>T	p.H518Y	Missense	13/19	-
1-11316096-T-A	MTOR	c.658A>T	p.T220S	Missense	5/58	-
19-52714695-C-G	PPP2R1A	c.453C>G	p.F151L	Missense	4/15	-
14-94696973-C-T	PPP4R4	c.344C>T	p.S115L	Missense	4/25	-
18-42643497-C-A	SETBP1	c.4625C>A	p.P1542H	Missense	6/6	-
12-54575953-G-A	SMUG1	c.740C>T	p.A247V	Missense	4/4	-
2-39213375-T-C	SOS1	c.3592A>G	p.I1198V	Missense	23/23	-
14-99641773-G-A	BCL11B	c.1400C>T	p.A467V	Missense	4/4	-
8-119123266-T-C	EXT1	c.20A>G	p.Y7C	Missense	1/11	-
1-3322159-C-T	PRDM16	c.1133C>T	p.S378F	Missense	8/17	-
9-35074426-T-C	FANCG	c.1702A>G	p.T568A	Missense	13/14	-
3-37089047-T-C	MLH1	c.1769T>C	p.L590S	Missense	16/19	-
3-138426063-C-A	PIK3CB	c.1468G>T	p.A490S	Missense	11/24	-
14-94712865-A-G	PPP4R4	c.1600A>G	p.M534V	Missense	14/25	-
20-62331957-G-A	ARFRP1	c.515C>T	p.T172I	Missense	7/8	-
1-150551451-G-A	MCL1	c.556C>T	p.L186F	Missense	1/3	-
14-81610038-T-A	TSHR	c.1636T>A	p.W546R	Missense	10/10	-
17-8110528-G-T	AURKB	c.364C>A	p.L122M	Missense	5/9	-
20-30309907-C-A	BCL2L1	c.115G>T	p.E39*	Nonsense	2/3	-
16-88958680-C-T	CBFA2T3	c.593G>A	p.R198H	Missense	4/12	-
1-59248705-G-A	JUN	c.38C>T	p.A13V	Missense	1/1	-
6-106554268-G-A	PRDM1	c.1796G>A	p.G599E	Missense	6/7	-
5-98239525-G-T	CHD1	c.343C>A	p.Q115K	Missense	4/36	-
2-191897798-C-G	STAT4	c.1930G>C	p.D644H	Missense	21/24	-
6-401745-G-T	IRF4	c.1067G>T	p.C356F	Missense	7/9	-
3-3215901-G-T	CRBN	c.219C>A	p.H73Q	Missense	3/11	-
3-3215901-G-C	CRBN	c.219C>G	p.H73Q	Missense	3/11	-
6-106536196-G-C	PRDM1	c.163G>C	p.E55Q	Missense	2/7	-
15-75091248-G-A	CSK	c.211G>A	p.V71M	Missense	4/13	-
5-98234380-C-G	CHD1	c.1174G>C	p.E392Q	Missense	9/36	-
15-90631701-C-A	IDH2	c.568G>T	p.G190C	Missense	5/11	-
14-35255422-T-C	BAZ1A	c.1516A>G	p.T506A	Missense	13/27	-
2-191900909-C-A	STAT4	c.1551G>T	p.M517I	Missense	17/24	-
10-98088561-A-G	DNTT	c.1087A>G	p.K363E	Missense	8/11	-
14-35255409-T-C	BAZ1A	c.1529A>G	p.D510G	Missense	13/27	-
5-86670020-T-C	RASA1	c.1817T>C	p.L606P	Missense	14/25	-
7-148514464-T-A	EZH2	c.1260A>T	p.Q420H	Missense	11/20	-
7-148514464-T-G	EZH2	c.1260A>C	p.Q420H	Missense	11/20	-
5-23526501-A-G	PRDM9	c.1304A>G	p.Q435R	Missense	11/11	-
16-81946205-G-T	PLCG2	c.1938G>T	p.W646C	Missense	19/33	-
14-81610038-T-C	TSHR	c.1636T>C	p.W546R	Missense	10/10	-
14-81610165-C-A	TSHR	c.1763C>A	p.T588K	Missense	10/10	-
17-79508379-C-A	FAAP100	c.2470G>T	p.D824Y	Missense	8/9	-
1-201982130-C-G	ELF3	c.654C>G	p.D218E	Missense	6/9	-
1-201982130-C-A	ELF3	c.654C>A	p.D218E	Missense	6/9	-
1-78432421-G-A	FUBP1	c.430C>T	p.P144S	Missense	7/20	-
5-161118980-G-T	GABRA6	c.860G>T	p.S287I	Missense	8/9	-
9-93606569-A-G	SYK	c.389A>G	p.E130G	Missense	2/14	-
7-141408649-G-C	WEE2	c.91G>C	p.E31Q	Missense	1/12	-
22-23653895-CC-AA	BCR	c.3194_3195delCCinsAA	p.S1065*	Nonsense	19/23	-
10-90773957-G-C	FAS	c.758G>C	p.G253A	Missense	9/9	-
16-81925084-C-T	PLCG2	c.875C>T	p.T292M	Missense	11/33	-
15-40895140-T-G	KNL1	c.11T>G	p.V4G	Missense	2/26	-
2-215645324-T-C	BARD1	c.1274A>G	p.N425S	Missense	4/11	-
16-23641319-G-C	PALB2	c.2156C>G	p.P719R	Missense	5/13	-
16-3640457-G-A	SLX4	c.3182C>T	p.S1061F	Missense	12/15	-
4-84383830-G-A	ABRAXAS1	c.1022C>T	p.P341L	Missense	9/9	-
3-3215758-G-A	CRBN	c.362C>T	p.A121V	Missense	3/11	-
7-148514321-C-A	EZH2	c.1403G>T	p.C468F	Missense	11/20	-
X-37029041-G-T	FAM47C	c.2558G>T	p.R853L	Missense	1/1	-
X-37028654-C-G	FAM47C	c.2171C>G	p.S724C	Missense	1/1	-
16-2096337-C-T	NTHL1	c.170G>A	p.R49H	Missense	2/6	-
4-55133743-C-A	PDGFRA	c.956C>A	p.P319H	Missense	7/23	-
10-70405890-A-G	TET1	c.3404A>G	p.H1135R	Missense	4/12	-
12-133225642-T-A	POLE	c.4022A>T	p.Q1341L	Missense	32/49	-
22-42526618-T-A	CYP2D6	c.176A>T	p.D59V	Missense	1/9	-
X-129200787-G-C	ELF4	c.1901C>G	p.S634C	Missense	9/9	-
6-152129231-T-C	ESR1	c.184T>C	p.F62L	Missense	1/8	-
8-139155277-T-A	FAM135B	c.3616A>T	p.N1206Y	Missense	16/20	-
12-475173-C-A	KDM5A	c.464G>T	p.G155V	Missense	4/28	-
1-120460307-C-T	NOTCH2	c.6008G>A	p.R2003Q	Missense	33/34	-
19-15292474-G-T	NOTCH3	c.2705C>A	p.T902N	Missense	17/33	-
19-50919942-A-C	POLD1	c.3029A>C	p.N1010T	Missense	24/27	-
3-142281419-T-G	ATR	c.825A>C	p.E275D	Missense	4/47	-
4-55133898-C-T	PDGFRA	c.1111C>T	p.Q371*	Nonsense	7/23	-
X-14883457-T-A	FANCB	c.176A>T	p.Q59L	Missense	3/10	-
4-25664129-C-G	SLC34A2	c.7C>G	p.P3A	Missense	2/13	-
20-39741443-T-C	TOP1	c.1330T>C	p.Y444H	Missense	14/21	-
6-151687910-C-A	ZBTB2	c.291G>T	p.Q97H	Missense	3/3	-
6-151687910-C-G	ZBTB2	c.291G>C	p.Q97H	Missense	3/3	-
6-163836351-G-T	QKI	c.126G>T	p.E42D	Missense	1/8	-
2-96919823-G-C	TMEM127	c.440C>G	p.S147C	Missense	4/4	-
6-151687300-C-G	ZBTB2	c.901G>C	p.D301H	Missense	3/3	-
16-56873485-G-C	NUP93	c.2189G>C	p.R730T	Missense	20/22	-
2-11332409-C-A	ROCK2	c.4028G>T	p.R1343L	Missense	32/33	-
15-50751262-T-G	USP8	c.401T>G	p.L134R	Missense	5/20	-
9-137321037-G-C	RXRA	c.994G>C	p.V332L	Missense	7/10	-
1-9775978-G-T	PIK3CD	c.442G>T	p.E148*	Nonsense	5/24	-
21-44840137-C-A	SIK1	c.949G>T	p.V317L	Missense	8/14	-
15-67457402-C-T	SMAD3	c.376C>T	p.H126Y	Missense	2/9	-
1-204506566-C-G	MDM4	c.352C>G	p.Q118E	Missense	6/11	-
17-47684667-C-G	SPOP	c.782G>C	p.G261A	Missense	8/10	-
5-98195684-C-G	CHD1	c.4516G>C	p.E1506Q	Missense	33/36	-
3-48604566-C-T	COL7A1	c.8104G>A	p.E2702K	Missense	110/119	-
17-37873719-C-G	ERBB2	c.1884C>G	p.I628M	Missense	15/27	-
3-148766779-C-G	HLTF	c.1627G>C	p.D543H	Missense	16/25	-
17-73658729-C-G	RECQL5	c.601G>C	p.E201Q	Missense	4/20	-
3-133371473-C-A	TOPBP1	c.923G>T	p.S308I	Missense	8/28	-
5-112176970-A-C	APC	c.5679A>C	p.K1893N	Missense	16/16	-
4-41748010-C-CGCG	PHOX2B	c.758_759insCGC	p.A260dup	InFrameInsertion	3/3	-
7-6414377-T-G	RAC1	c.11T>G	p.I4S	Missense	1/6	-
16-23619272-G-A	PALB2	c.3263C>T	p.P1088L	Missense	12/13	-
8-139278019-AA-GG	FAM135B	c.223_224delTTinsCC	p.L75P	Missense	4/20	-
2-141299518-CC-AG	LRP1B	c.7216_7217delGGinsCT	p.G2406L	Missense	44/91	-
9-87339236-G-C	NTRK2	c.818G>C	p.G273A	Missense	8/19	-
16-23632710-G-C	PALB2	c.3086C>G	p.T1029S	Missense	10/13	-
16-23632711-T-A	PALB2	c.3085A>T	p.T1029S	Missense	10/13	-
9-35074183-C-A	FANCG	c.1791G>T	p.L597F	Missense	14/14	-
9-35074183-C-G	FANCG	c.1791G>C	p.L597F	Missense	14/14	-
2-141359206-C-G	LRP1B	c.6802G>C	p.V2268L	Missense	42/91	-
2-141359206-C-A	LRP1B	c.6802G>T	p.V2268L	Missense	42/91	-
9-139403421-C-G	NOTCH1	c.3072G>C	p.E1024D	Missense	19/34	-
9-139403421-C-A	NOTCH1	c.3072G>T	p.E1024D	Missense	19/34	-
16-23641769-T-A	PALB2	c.1706A>T	p.K569I	Missense	5/13	-
16-23646653-G-A	PALB2	c.1214C>T	p.P405L	Missense	4/13	-
6-18134039-A-C	TPMT	c.576T>G	p.H192Q	Missense	7/9	-
14-99641790-G-C	BCL11B	c.1383C>G	p.D461E	Missense	4/4	-
15-91293158-G-C	BLM	c.660G>C	p.L220F	Missense	3/22	-
19-30313507-G-T	CCNE1	c.1107G>T	p.L369F	Missense	11/12	-
5-180046069-G-C	FLT4	c.2802C>G	p.N934K	Missense	20/30	-
9-110068921-A-G	RAD23B	c.490A>G	p.T164A	Missense	4/10	-
17-17124862-T-C	FLCN	c.860A>G	p.E287G	Missense	8/14	-
5-112154742-C-G	APC	c.1013C>G	p.S338C	Missense	10/16	-
20-31019195-C-G	ASXL1	c.790C>G	p.L264V	Missense	9/13	-
17-29556062-A-G	NF1	c.2429A>G	p.K810R	Missense	21/58	-
16-88952418-C-T	CBFA2T3	c.844G>A	p.E282K	Missense	6/12	-
11-32421503-T-A	WT1	c.1089A>T	p.R368S	Missense	6/10	-
2-30143423-C-T	ALK	c.103G>A	p.G35R	Missense	1/29	-
22-21288380-C-G	CRKL	c.625C>G	p.Q209E	Missense	2/3	-
17-73659047-C-A	RECQL5	c.283G>T	p.V95L	Missense	4/20	-
12-133218333-C-T	POLE	c.5278G>A	p.V1760M	Missense	39/49	-
10-84745348-C-T	NRG3	c.2078C>T	p.A693V	Missense	9/9	-
12-109530489-C-T	ALKBH2	c.103G>A	p.E35K	Missense	2/4	-
14-99641914-G-T	BCL11B	c.1259C>A	p.P420Q	Missense	4/4	-
5-24509755-T-G	CDH10	c.1176A>C	p.E392D	Missense	7/12	-
5-158158150-G-C	EBF1	c.1052C>G	p.T351S	Missense	11/16	-
3-134977930-C-G	EPHB1	c.2923C>G	p.Q975E	Missense	16/16	-
1-241672010-G-T	FH	c.631C>A	p.L211I	Missense	5/10	-
9-101611241-C-G	GALNT12	c.1613C>G	p.S538C	Missense	10/10	-
7-151860637-G-A	KMT2C	c.10025C>T	p.A3342V	Missense	43/59	-
1-120459022-G-A	NOTCH2	c.6323C>T	p.A2108V	Missense	34/34	-
6-32164755-A-C	NOTCH4	c.5147T>G	p.L1716R	Missense	28/30	-
15-88678477-G-C	NTRK3	c.1059C>G	p.Y353*	Nonsense	10/20	-
2-109370294-A-T	RANBP2	c.2069A>T	p.K690M	Missense	15/29	-
17-78305988-C-T	RNF213	c.3700C>T	p.Q1234*	Nonsense	21/68	-
16-2107170-T-A	TSC2	c.839T>A	p.M280K	Missense	9/42	-
11-2154854-C-A	IGF2	c.199G>T	p.V67F	Missense	3/4	-
13-48955533-T-C	RB1	c.1649T>C	p.L550S	Missense	17/27	-
16-23646387-T-A	PALB2	c.1480A>T	p.T494S	Missense	4/13	-
8-41615628-C-T	ANK1	c.55G>A	p.A19T	Missense	2/43	-
X-70340983-T-C	MED12	c.716T>C	p.L239P	Missense	5/45	-
8-128752836-G-A	MYC	c.997G>A	p.D333N	Missense	3/3	-
2-141747214-C-A	LRP1B	c.2657G>T	p.C886F	Missense	17/91	-
5-79968150-G-T	MSH3	c.880G>T	p.V294L	Missense	5/24	-
16-23646202-T-G	PALB2	c.1665A>C	p.K555N	Missense	4/13	-
2-215617257-C-A	BARD1	c.1591G>T	p.V531F	Missense	7/11	-
2-215610571-G-C	BARD1	c.1685C>G	p.T562S	Missense	8/11	-
2-141299473-G-T	LRP1B	c.7262C>A	p.S2421*	Nonsense	44/91	-
16-89833611-T-C	FANCA	c.2539A>G	p.K847E	Missense	27/43	-
5-112177289-A-T	APC	c.5998A>T	p.S2000C	Missense	16/16	-
16-23625338-G-A	PALB2	c.3188C>T	p.A1063V	Missense	11/13	-
19-11121162-C-G	SMARCA4	c.2229C>G	p.D743E	Missense	15/35	-
1-11301690-G-C	MTOR	c.1461C>G	p.S487R	Missense	10/58	-
5-112179035-G-T	APC	c.7744G>T	p.E2582*	Nonsense	16/16	-
5-112176623-C-A	APC	c.5332C>A	p.P1778T	Missense	16/16	-
11-108115643-A-G	ATM	c.791A>G	p.Y264C	Missense	7/63	-
16-3832750-T-C	CREBBP	c.1508A>G	p.Q503R	Missense	6/31	-
2-29445399-A-C	ALK	c.3434T>G	p.L1145R	Missense	21/29	-
3-142217515-C-T	ATR	c.5482G>A	p.A1828T	Missense	32/47	-
16-23637581-T-A	PALB2	c.2724A>T	p.K908N	Missense	7/13	-
4-99273682-G-T	RAP1GDS1	c.291G>T	p.L97=	Synonymous	4/15	-
X-63412508-G-T	AMER1	c.659C>A	p.T220N	Missense	2/2	-
14-99640744-T-C	BCL11B	c.2429A>G	p.N810S	Missense	4/4	-
X-39933644-T-C	BCOR	c.955A>G	p.K319E	Missense	4/15	-
7-2959221-C-A	CARD11	c.2295G>T	p.M765I	Missense	18/25	-
11-47238458-A-G	DDB2	c.314A>G	p.Q105R	Missense	3/10	-
11-108550233-G-T	DDX10	c.794G>T	p.R265L	Missense	6/18	-
8-109215669-A-C	EIF3E	c.1125T>G	p.I375M	Missense	11/13	-
7-42007467-T-A	GLI3	c.2158A>T	p.I720F	Missense	14/15	-
20-57485766-G-T	GNAS	c.1067G>T	p.R356L	Missense	13/13	-
11-128781947-G-T	KCNJ5	c.779G>T	p.G260V	Missense	2/3	-
2-141777648-C-T	LRP1B	c.1813G>A	p.A605T	Missense	12/91	-
2-141299466-C-T	LRP1B	c.7269G>A	p.W2423*	Nonsense	44/91	-
1-150551597-C-T	MCL1	c.410G>A	p.R137Q	Missense	1/3	-
1-11313970-T-A	MTOR	c.766A>T	p.N256Y	Missense	6/58	-
1-11308109-C-T	MTOR	c.883G>A	p.V295I	Missense	7/58	-
15-88483888-C-A	NTRK3	c.1682G>T	p.S561I	Missense	15/20	-
15-88476311-G-T	NTRK3	c.1821C>A	p.C607*	Nonsense	16/20	-
7-124503430-C-A	POT1	c.520G>T	p.V174L	Missense	8/19	-
5-23526649-G-T	PRDM9	c.1452G>T	p.M484I	Missense	11/11	-
9-8499744-C-G	PTPRD	c.2225G>C	p.G742A	Missense	25/46	-
10-43604668-G-T	RET	c.1253G>T	p.R418L	Missense	6/20	-
11-114027115-T-A	ZBTB16	c.1325T>A	p.L442Q	Missense	3/7	-
3-142277595-T-C	ATR	c.1756A>G	p.I586V	Missense	8/47	-
9-98248051-G-T	PTCH1	c.500C>A	p.A167D	Missense	3/24	-
5-24488084-C-G	CDH10	c.2055G>C	p.K685N	Missense	12/12	-
7-101840577-G-T	CUX1	c.1886G>T	p.R629I	Missense	15/24	-
15-31218038-C-T	FAN1	c.2384C>T	p.S795F	Missense	10/15	-
16-3820740-CC-AA	CREBBP	c.2710_2711delGGinsTT	p.G904F	Missense	14/31	-
16-3900805-C-A	CREBBP	c.291G>T	p.Q97H	Missense	2/31	-
1-59248182-C-T	JUN	c.561G>A	p.A187=	Synonymous	1/1	-
1-59248182-C-G	JUN	c.561G>C	p.A187=	Synonymous	1/1	-
1-59248182-C-A	JUN	c.561G>T	p.A187=	Synonymous	1/1	-
5-112177334-G-A	APC	c.6043G>A	p.E2015K	Missense	16/16	-
1-65303712-G-T	JAK1	c.3043C>A	p.H1015N	Missense	22/25	-
12-57550679-G-T	LRP1	c.1537G>T	p.G513C	Missense	10/89	-
1-156841416-A-G	NTRK1	c.719A>G	p.K240R	Missense	7/17	-
7-42007449-T-A	GLI3	c.2176A>T	p.S726C	Missense	14/15	-
5-112162905-G-A	APC	c.1509G>A	p.M503I	Missense	12/16	-
16-23641769-T-C	PALB2	c.1706A>G	p.K569R	Missense	5/13	-
9-101911584-G-A	TGFBR1	c.1509G>A	p.M503I	Missense	9/9	-
2-141812700-C-A	LRP1B	c.1537G>T	p.G513C	Missense	10/91	-
1-158606447-T-A	SPTA1	c.5294A>T	p.H1765L	Missense	37/52	-
4-20521021-A-T	SLIT2	c.1075A>T	p.K359*	Nonsense	12/37	-
19-50912437-G-T	POLD1	c.1951G>T	p.V651L	Missense	16/27	-
8-37691499-G-T	ADGRA2	c.1461G>T	p.M487I	Missense	11/19	-
8-93026893-T-C	RUNX1T1	c.271A>G	p.R91G	Missense	3/11	-
X-123184135-T-A	STAG2	c.993T>A	p.Y331*	Nonsense	11/35	-
3-142231103-C-T	ATR	c.4851G>A	p.M1617I	Missense	27/47	-
16-23641522-TCC-CCA	PALB2	c.1951_1953delGGAinsTGG	p.G651W	Missense	5/13	-
9-93641146-AGA-CAT	SYK	c.1492_1494delAGAinsCAT	p.R498H	Missense	11/14	-
16-68845705-C-G	CDH1	c.951C>G	p.F317L	Missense	7/16	-
5-112175141-G-C	APC	c.3850G>C	p.E1284Q	Missense	16/16	-
1-156848999-G-T	NTRK1	c.1891G>T	p.A631S	Missense	15/17	-
11-69514130-T-A	FGF19	c.551A>T	p.E184V	Missense	3/3	-
16-23646339-T-C	PALB2	c.1528A>G	p.R510G	Missense	4/13	-
5-112178805-G-C	APC	c.7514G>C	p.R2505P	Missense	16/16	-
5-79974857-C-T	MSH3	c.1285C>T	p.P429S	Missense	8/24	-
18-9559596-C-G	PPP4R1	c.1849G>C	p.V617L	Missense	14/20	-
9-2086997-C-T	SMARCA2	c.2695C>T	p.L899F	Missense	18/34	-
X-123164949-G-T	STAG2	c.262G>T	p.V88F	Missense	5/35	-
2-169792916-C-A	ABCB11	c.2638G>T	p.V880F	Missense	22/28	-
2-29462590-G-T	ALK	c.2311C>A	p.L771M	Missense	13/29	-
7-2968297-G-C	CARD11	c.1689C>G	p.I563M	Missense	13/25	-
5-11018094-A-G	CTNND2	c.3076T>C	p.Y1026H	Missense	18/22	-
1-242048737-A-G	EXO1	c.2333A>G	p.H778R	Missense	15/16	-
8-139209846-G-T	FAM135B	c.736C>A	p.L246M	Missense	8/20	-
8-139165234-C-T	FAM135B	c.1484G>A	p.C495Y	Missense	13/20	-
14-45623204-G-T	FANCM	c.1132G>T	p.G378*	Nonsense	6/23	-
4-187584757-C-A	FAT1	c.3276G>T	p.E1092D	Missense	3/27	-
4-187510374-C-A	FAT1	c.13139G>T	p.G4380V	Missense	27/27	-
11-118376344-T-G	KMT2A	c.9737T>G	p.I3246S	Missense	27/36	-
2-140992428-C-A	LRP1B	c.13586G>T	p.S4529I	Missense	90/91	-
16-23641726-C-G	PALB2	c.1749G>C	p.L583F	Missense	5/13	-
14-62016445-A-C	PRKCH	c.1948A>C	p.K650Q	Missense	14/14	-
4-20550161-A-T	SLIT2	c.2396A>T	p.N799I	Missense	23/37	-
16-3642800-C-T	SLX4	c.2227G>A	p.V743M	Missense	11/15	-
3-181430515-G-T	SOX2	c.367G>T	p.D123Y	Missense	1/1	-
3-105586309-T-C	CBLB	c.113A>G	p.Q38R	Missense	2/19	-
9-21971183-C-A	CDKN2A	c.175G>T	p.V59L	Missense	2/3	-
8-139164829-A-T	FAM135B	c.1889T>A	p.L630Q	Missense	13/20	-
2-17954489-A-T	GEN1	c.994A>T	p.I332F	Missense	10/14	-
1-92948511-C-T	GFI1	c.208G>A	p.A70T	Missense	3/7	-
1-92946270-C-T	GFI1	c.674G>A	p.R225H	Missense	4/7	-
10-64949190-C-T	JMJD1C	c.6308G>A	p.R2103Q	Missense	18/26	-
2-16085894-G-T	MYCN	c.1070G>T	p.R357L	Missense	3/3	-
16-81941359-A-G	PLCG2	c.1537A>G	p.M513V	Missense	16/33	-
2-55791607-C-A	PPP4R3B	c.2102G>T	p.R701I	Missense	15/17	-
9-8528615-C-T	PTPRD	c.517G>A	p.G173S	Missense	15/46	-
18-20581605-G-A	RBBP8	c.2200G>A	p.E734K	Missense	15/19	-
17-78363006-A-G	RNF213	c.15034A>G	p.S5012G	Missense	65/68	-
16-3646361-G-A	SLX4	c.1717C>T	p.P573S	Missense	8/15	-
1-158617406-G-T	SPTA1	c.3819C>A	p.D1273E	Missense	27/52	-
16-72821620-C-T	ZFHX3	c.10555G>A	p.G3519S	Missense	10/10	-
16-2111939-ACCAGAACGAGTT-A	TSC2	c.1191_1202del12	p.Q397_F400del	InFrameDeletion	12/42	-
1-98157294-T-G	DPYD	c.741A>C	p.L247=	Synonymous	7/23	-
16-23649444-C-T	PALB2	c.55G>A	p.E19K	Missense	2/13	-
9-135772878-G-C	TSC1	c.2745C>G	p.H915Q	Missense	21/23	-
16-23632777-T-A	PALB2	c.3019A>T	p.M1007L	Missense	10/13	-
1-158590216-G-T	SPTA1	c.6161C>A	p.A2054D	Missense	44/52	-
15-91347400-G-A	BLM	c.3562G>A	p.D1188N	Missense	19/22	-
16-23646393-C-A	PALB2	c.1474G>T	p.G492W	Missense	4/13	-
3-183245796-G-T	KLHL6	c.296C>A	p.A99D	Missense	2/7	-
8-41812896-C-A	KAT6A	c.1516G>T	p.V506F	Missense	9/17	-
2-141571310-T-A	LRP1B	c.5275A>T	p.R1759*	Nonsense	32/91	-
4-110932529-A-T	EGF	c.3542A>T	p.K1181M	Missense	24/24	-
9-2047229-G-T	SMARCA2	c.791G>T	p.G264V	Missense	5/34	-
14-95590793-A-T	DICER1	c.1116T>A	p.F372L	Missense	8/27	-
21-44840229-C-T	SIK1	c.857G>A	p.G286E	Missense	8/14	-
11-94204796-G-C	MRE11	c.789C>G	p.I263M	Missense	8/20	-
14-35872380-T-A	NFKBIA	c.523A>T	p.I175F	Missense	3/6	-
13-28578233-C-G	FLT3	c.2938G>C	p.D980H	Missense	24/24	-
2-141200116-G-C	LRP1B	c.10371C>G	p.D3457E	Missense	66/91	-
17-7578451-ATGGCGCGGACGCGGG-A	TP53	c.464_478del15	p.T155_A159del	InFrameDeletion	5/11	-
9-98270534-C-T	PTCH1	c.110G>A	p.G37E	Missense	1/24	-
4-110908944-T-C	EGF	c.2536T>C	p.C846R	Missense	17/24	-
1-158627327-G-C	SPTA1	c.2745C>G	p.I915M	Missense	19/52	-
2-29449919-A-T	ALK	c.2936T>A	p.V979E	Missense	18/29	-
15-91292785-G-T	BLM	c.287G>T	p.G96V	Missense	3/22	-
16-9858269-G-T	GRIN2A	c.3132C>A	p.H1044Q	Missense	13/13	-
4-187630783-C-A	FAT1	c.199G>T	p.A67S	Missense	2/27	-
7-2946433-C-A	CARD11	c.3304G>T	p.V1102L	Missense	25/25	-
15-88678557-C-A	NTRK3	c.979G>T	p.G327C	Missens