PMID: 35117215

Association between BRAF mutant classification and the efficacy of pemetrexed-based chemotherapy in Chinese advanced non-small cell lung cancer patients: a multicenter retrospective study.

Translational cancer research

Lei, Lei L, Wang, Wen-Xian WX, Zhu, You-Cai YC, Pu, Xing-Xiang XX, Fang, Yong Y, Wang, Hong H, Zhuang, Wu W, Zhang, Yin-Bin YB, Wang, Li-Ping LP, Xu, Chun-Wei CW, Fang, Mei-Yu MY

2020-10

32 variants were identified in this publication

Variant ID	Gene	cDNA	Protein	Consequence	Exon	Intron
7-140494131-T-A	BRAF	c.1117A>T	p.T373S	Missense	8/18	-
7-140494148-G-A	BRAF	c.1100C>T	p.P367L	Missense	8/18	-
7-140453129-AGA-TGTGTT	BRAF	c.1804_1806delinsAACACA	p.S602delinsNT	MultiAAMissense	15/18	-
7-140494154-G-T	BRAF	c.1094C>A	p.S365*	Nonsense	8/18	-
7-140494154-G-C	BRAF	c.1094C>G	p.S365*	Nonsense	8/18	-
7-140494118-A-T	BRAF	c.1130T>A	p.V377D	Missense	8/18	-
7-140477854-A-C	BRAF	c.1454T>G	p.L485W	Missense	12/18	-
7-140454023-C-T	BRAF	c.1705G>A	p.A569T	Missense	14/18	-
7-140477838-TAGG-T	BRAF	c.1468_1470delCCT	p.P490del	InFrameDeletion	12/18	-
7-140481411-C-A	BRAF	c.1397G>T	p.G466V	Missense	11/18	-
7-140453193-T-C	BRAF	c.1742A>G	p.N581S	Missense	15/18	-
7-140481417-C-A	BRAF	c.1391G>T	p.G464V	Missense	11/18	-
7-140453154-T-G	BRAF	c.1781A>C	p.D594A	Missense	15/18	-
7-140481402-C-T	BRAF	c.1406G>A	p.G469E	Missense	11/18	-
7-140453148-C-T	BRAF	c.1787G>A	p.G596D	Missense	15/18	-
7-140453152-A-G	BRAF	c.1783T>C	p.F595L	Missense	15/18	-
7-140453150-A-T	BRAF	c.1785T>A	p.F595L	Missense	15/18	-
7-140453150-A-C	BRAF	c.1785T>G	p.F595L	Missense	15/18	-
7-140453145-A-T	BRAF	c.1790T>A	p.L597Q	Missense	15/18	-
7-140481411-C-G	BRAF	c.1397G>C	p.G466A	Missense	11/18	-
7-140434564-C-T	BRAF	c.2134G>A	p.A712T	Missense	18/18	-
7-140453179-C-T	BRAF	c.1756G>A	p.E586K	Missense	15/18	-
7-140481408-G-A	BRAF	c.1400C>T	p.S467L	Missense	11/18	-
7-140624440-C-T	BRAF	c.64G>A	p.D22N	Missense	1/18	-
7-140481433-C-G	BRAF	c.1375G>C	p.V459L	Missense	11/18	-
7-140481433-C-A	BRAF	c.1375G>T	p.V459L	Missense	11/18	-
7-140453138-T-G	BRAF	c.1797A>C	p.T599=	Synonymous	15/18	-
7-140453138-T-C	BRAF	c.1797A>G	p.T599=	Synonymous	15/18	-
7-140453138-T-A	BRAF	c.1797A>T	p.T599=	Synonymous	15/18	-
7-140501213-C-G	BRAF	c.859G>C	p.D287H	Missense	6/18	-
7-140481397-C-T	BRAF	c.1411G>A	p.V471I	Missense	11/18	-
7-140481457-C-G	BRAF	c.1351G>C	p.E451Q	Missense	11/18	-