PMID: 35207726

Immune Response and Lipid Metabolism Gene Polymorphisms Are Associated with the Risk of Obesity in Middle-Aged and Elderly Patients.

Journal of personalized medicine
Ponasenko, Anastasia A, Sinitsky, Maxim M, Minina, Varvara V, Vesnina, Anna A, Khutornaya, Maria M, Prosekov, Alexander A, Barbarash, Olga O
2022-02-08

36 variants were identified in this publication


Variant ID Gene cDNA Protein Consequence Exon Intron
2-102986375-G-A IL18R1 c.302+1847G>A - IntronicSNV - 3/10
2-102991369-G-A IL18R1 c.469-998G>A - IntronicSNV - 4/10
19-18180451-A-G IL12RB1 c.1094T>C p.M365T Missense 10/17 -
2-219029843-A-C CXCR1 c.92T>G p.M31R Missense 2/2 -
2-102968007-G-A IL1RL1 c.1297G>A p.A433T Missense 11/11 -
4-74607055-C-T CXCL8 c.65-204C>T - IntronicSNV - 1/3
5-158742950-T-G IL12B c.*159A>C - 3_prime_UTR_variant 8/8 -
16-53820527-T-A FTO c.46-23525T>A - IntronicSNV - 1/8
1-159682233-C-T CRP c.*1082G>A - 3-UTRSNV 2/2 -
6-161010118-A-G LPA c.3947+467T>C - IntronicSNV - 24/38
1-159683091-G-A CRP c.*224C>T - 3-UTRSNV 2/2 -
11-2182224-A-T INS c.1-23T>A - IntronicSNV - 1/2
7-22768707-T-A IL6 c.324+282T>A - IntronicSNV - 3/4
7-22768707-T-G IL6 c.324+282T>G - IntronicSNV - 3/4
2-219000734-T-C CXCR2 c.*127T>C - 3-UTRSNV 3/3 -
2-113590390-G-A IL1B c.315C>T p.F105= Synonymous 5/7 -
1-154426970-A-C IL6R c.1073A>C p.D358A Missense 9/10 -
1-154426970-A-T IL6R c.1073A>T p.D358V Missense 9/10 -
9-120475602-C-T TLR4 c.1196C>T p.T399I Missense 3/3 -
9-120475302-A-G TLR4 c.896A>G p.D299G Missense 3/3 -
9-120475302-A-T TLR4 c.896A>T p.D299V Missense 3/3 -
1-66036441-A-G LEPR c.326A>G p.K109R Missense 4/20 -
1-159683438-C-A CRP c.552G>T p.L184= Synonymous 2/2 -
1-159683438-C-G CRP c.552G>C p.L184= Synonymous 2/2 -
1-159683438-C-T CRP c.552G>A p.L184= Synonymous 2/2 -
1-66058513-A-G LEPR c.668A>G p.Q223R Missense 6/20 -
2-21225753-C-T APOB c.12541G>A p.E4181K Missense 29/29 -
2-21225753-C-A APOB c.12541G>T p.E4181* Nonsense 29/29 -
2-102978459-C-T IL18R1 c.1-662C>T - IntergenicSNV - 1/10
15-99478225-G-A IGF1R c.3129G>A p.E1043= Synonymous 16/21 -
4-38800214-C-G TLR1 c.239G>C p.R80T Missense 4/4 -
9-6240084-T-C IL33 c.1-1611T>C - IntronicSNV - 1/7
9-6240084-T-G IL33 c.1-1611T>G - IntronicSNV - 1/7
19-45411110-T-C APOE c.137T>C p.L46P Missense 3/4 -
1-154437896-T-A IL6R c.*40T>A - 3-UTRSNV 10/10 -
1-154437896-T-C IL6R c.*40T>C - 3-UTRSNV 10/10 -