PMID: 37059834

Dabrafenib plus trametinib in BRAFV600E-mutated rare cancers: the phase 2 ROAR trial.

Nature medicine

Subbiah, Vivek V, Kreitman, Robert J RJ, Wainberg, Zev A ZA, Gazzah, Anas A, Lassen, Ulrik U, Stein, Alexander A, Wen, Patrick Y PY, Dietrich, Sascha S, de Jonge, Maja J A MJA, Blay, Jean-Yves JY, Italiano, Antoine A, Yonemori, Kan K, Cho, Daniel C DC, de Vos, Filip Y F L FYFL, Moreau, Philippe P, Fernandez, Elena Elez EE, Schellens, Jan H M JHM, Zielinski, Christoph C CC, Redhu, Suman S, Boran, Aislyn A, Passos, Vanessa Q VQ, Ilankumaran, Palanichamy P, Bang, Yung-Jue YJ

2023-04-14

2 variants were identified in this publication

Variant ID	Gene	cDNA	Protein	Consequence	Exon	Intron
7-140453136-AC-TT	BRAF	c.1798_1799delGTinsAA	p.V600K	Missense	15/18	-
7-140453136-A-T	BRAF	c.1799T>A	p.V600E	Missense	15/18	-