NRAS c.481_482delinsGC ;(p.R161A)

Variant ID: 1-115251244-CT-GC

NM_002524.4(NRAS):c.481_482delinsGC;(p.R161A)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Specific cancer-associated mutations in the switch III region of Ras increase tumorigenicity by nanocluster augmentation.

Elife
Šolman, Maja M; Ligabue, Alessio A; Blaževitš, Olga O; Jaiswal, Alok A; Zhou, Yong Y; Liang, Hong H; Lectez, Benoit B; Kopra, Kari K; Guzmán, Camilo C; Härmä, Harri H; Hancock, John F JF; Aittokallio, Tero T; Abankwa, Daniel D
Publication Date: 2015-08-14

Variant appearance in text: N-ras: R161A
PubMed Link: 26274561
Variant Present in the following documents:
  • Main text
  • elife08905.pdf
View BVdb publication page



A novel switch region regulates H-ras membrane orientation and signal output.

The Embo Journal
Abankwa, Daniel D; Hanzal-Bayer, Michael M; Ariotti, Nicolas N; Plowman, Sarah J SJ; Gorfe, Alemayehu A AA; Parton, Robert G RG; McCammon, J Andrew JA; Hancock, John F JF
Publication Date: 2008-03-05

Variant appearance in text: N-ras: R161A
PubMed Link: 18273062
Variant Present in the following documents:
  • Main text
View BVdb publication page