Publications:

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RAS-targeted cancer therapy: Advances in drugging specific mutations.

Medcomm

Liu, Cen C; Ye, Danyang D; Yang, Hongliu H; Chen, Xu X; Su, Zhijun Z; Li, Xia X; Ding, Mei M; Liu, Yonggang Y

Publication Date: 2023-06

Variant appearance in text: NRAS: A146T

PubMed Link: 37250144

Variant Present in the following documents:

• Main text

View BVdb publication page

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Molecular profiling of colorectal cancer in a genetically admixed Hispanic population.

Cancer Medicine

Montes-Rodríguez, Ingrid M IM; Centeno-Girona, Hilmaris H; Rivera-Lynch, Camila C; Rivera, Noridza N; Cruz-Correa, Marcia M

Publication Date: 2023-04-11

Variant appearance in text: NRAS: A146T

PubMed Link: 37039257

Variant Present in the following documents:

• CAM4-12-11686-s002.xlsx, sheet 1

View BVdb publication page

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Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: NRAS: A146T

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2

View BVdb publication page

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Somatic mutation detection and KRAS amplification in testicular germ cell tumors.

Frontiers In Oncology

Cabral, Eduardo R M ERM; Pacanhella, Marilia F MF; Lengert, Andre V H AVH; Dos Reis, Mariana B MB; Leal, Leticia F LF; de Lima, Marcos A MA; da Silva, Aline L V ALV; Pinto, Icaro A IA; Reis, Rui M RM; Pinto, Mariana T MT; Cárcano, Flavio M FM

Publication Date: 2023

Variant appearance in text: NRAS: A146T

PubMed Link: 37007070

Variant Present in the following documents:

• fonc-13-1133363.pdf

View BVdb publication page

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Characteristics and prognosis of rrDLBCL with TP53 mutations and a high-risk subgroup represented by the co-mutations of DDX3X-TP53.

Cancer Medicine

Gao, Fan F; Hu, Kai K; Zheng, Peihao P; Shi, Hui H; Ke, Xiaoyan X

Publication Date: 2023-03-27

Variant appearance in text: NRAS: 436G>A; A146T

PubMed Link: 36971051

Variant Present in the following documents:

• CAM4-12-10267-s001.xlsx, sheet 1

View BVdb publication page

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KRAS, NRAS, BRAF, and PIK3CA mutation rates, clinicopathological association, and their prognostic value in Iranian colorectal cancer patients.

Journal Of Clinical Laboratory Analysis

Mirzapoor Abbasabadi, Zohreh Z; Hamedi Asl, Dariush D; Rahmani, Babak B; Shahbadori, Rozhin R; Karami, Sara S; Peymani, Amir A; Taghizadeh, Sara S; Samiee Rad, Fatemeh F

Publication Date: 2023-03-17

Variant appearance in text: NRAS: A146T

PubMed Link: 36930789

Variant Present in the following documents:

• JCLA-37-e24868.pdf

View BVdb publication page

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Dynamics of age- versus therapy-related clonal hematopoiesis in long-term survivors of pediatric cancer.

Cancer Discovery

Hagiwara, Kohei K; Natarajan, Sivaraman S; Wang, Zhaoming Z; Zubair, Haseeb H; Mulder, Heather L HL; Dong, Li L; Plyler, Emily M EM; Thimmaiah, Padma P; Ma, Xiaotu X; Ness, Kirsten K KK; Li, Zhenghong Z; Mulrooney, Daniel A DA; Wilson, Carmen L CL; Yasui, Yutaka Y; Hudson, Melissa M MM; Easton, John J; Robison, Leslie L LL; Zhang, Jinghui J

Publication Date: 2023-02-08

Variant appearance in text: NRAS: A146T

PubMed Link: 36751942

Variant Present in the following documents:

• cd-22-0956_tables_s2_s7_s8_s9_suppst1.xlsx, sheet 1

View BVdb publication page

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Patient-derived xenograft models for gastrointestinal tumors: A single-center retrospective study.

Frontiers In Oncology

Yu, Xiongfei X; Chen, Yiran Y; Lu, Jun J; He, Kuifeng K; Chen, Yanyan Y; Ding, Yongfeng Y; Jin, Ketao K; Wang, Haiyong H; Zhang, Haibin H; Wang, Haohao H; Teng, Lisong L

Publication Date: 2022

Variant appearance in text: NRAS: A146T

PubMed Link: 36465411

Variant Present in the following documents:

• Table_1.xlsx, sheet 5

View BVdb publication page

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Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Cheng, Wen-Yan WY; Li, Jian-Feng JF; Zhu, Yong-Mei YM; Lin, Xiang-Jie XJ; Wen, Li-Jun LJ; Zhang, Fan F; Zhang, Yu-Liang YL; Zhao, Ming M; Fang, Hai H; Wang, Sheng-Yue SY; Lin, Xiao-Jing XJ; Qiao, Niu N; Yin, Wei W; Zhang, Jia-Nan JN; Dai, Yu-Ting YT; Jiang, Lu L; Sun, Xiao-Jian XJ; Xu, Yi Y; Zhang, Tong-Tong TT; Chen, Su-Ning SN; Zhu, Hong-Hu HH; Chen, Zhu Z; Jin, Jie J; Wu, De-Pei DP; Shen, Yang Y; Chen, Sai-Juan SJ

Publication Date: 2022-12-06

Variant appearance in text: NRAS: A146T

PubMed Link: 36442087

Variant Present in the following documents:

• pnas.2211429119.sd02.xlsx, sheet 1

View BVdb publication page

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A sex-informed approach to improve the personalised decision making process in myelodysplastic syndromes: a multicentre, observational cohort study.

The Lancet. Haematology

,

Publication Date: 2022-11-24

Variant appearance in text: NRAS: 436G>A; A146T

PubMed Link: 36436542

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

View BVdb publication page

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Rosai-Dorfman Disease between Proliferation and Neoplasia.

Cancers

Elbaz Younes, Ismail I; Sokol, Lubomir L; Zhang, Ling L

Publication Date: 2022-10-27

Variant appearance in text: NRAS: A146T

PubMed Link: 36358690

Variant Present in the following documents:

• Main text
• cancers-14-05271.pdf

View BVdb publication page

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Clinical profile in KMT2A-SEPT6-positive acute myeloid leukemia: Does it often co-occur with NRAS mutations?

Frontiers In Medicine

Chen, Fang F; Yang, Ying Y; Fu, Shuang S

Publication Date: 2022

Variant appearance in text: NRAS: A146T

PubMed Link: 36213638

Variant Present in the following documents:

• Main text
• fmed-09-890959.pdf

View BVdb publication page

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A comprehensive next generation sequencing tissue assay for Asian-prevalent cancers-Analytical validation and performance evaluation with clinical samples.

Frontiers In Molecular Biosciences

Ng, Cedric Chuan-Young CC; Lim, Sandy S; Lim, Abner Herbert AH; Md Nasir, Nur Diyana ND; Zhang, Jingxian J; Rajasegaran, Vikneswari V; Lee, Jing Yi JY; Kok, Jessica Sook Ting JST; Thike, Aye Aye AA; Lim, Johnathan Xiande JX; Weng, Ruifen R; Yee, Sidney S; Choudhury, Yukti Y; Chan, Jason Yongsheng JY; Tan, Puay Hoon PH; Tan, Min-Han MH; Teh, Bin Tean BT

Publication Date: 2022

Variant appearance in text: NRAS: A146T

PubMed Link: 36213130

Variant Present in the following documents:

• DataSheet1.xlsx, sheet 9

View BVdb publication page

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Distinguishing STAT3/STAT5B Mutated Large Granular Lymphocyte Leukemia from Myeloid Neoplasms by Genetic Profiling.

Blood Advances

Kavesh, Mark M; Mohebnasab, Maedeh M; Angel, Marcela Riveros MR; Xie, Wei W; Raess, Philipp W PW; Cui, Wei W; Press, Richard D RD; Yang, Guang G; Li, Peng P

Publication Date: 2022-08-08

Variant appearance in text: NRAS: 436G>A; A146T

PubMed Link: 35939786

Variant Present in the following documents:

• BLOODA_ADV-2022-008192-mmc1.pdf

View BVdb publication page

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Genetic landscapes and curative effect of CAR T-cell immunotherapy in relapse and refractory DLBCL patients.

Blood Advances

Shi, Hui H; Zheng, Peihao P; Liu, Rui R; Xu, Teng T; Yang, Fan F; Feng, Shaomei S; Guo, Yuelu Y; Ma, Lixia L; Liu, Haidi H; Lei, Yang Y; Li, Ruiting R; Deng, Biping B; Hou, Shuling S; Li, Yang Y; Zheng, Qinlong Q; Hu, Kai K; Ke, Xiaoyan X

Publication Date: 2022-07-28

Variant appearance in text: NRAS: 436G>A; A146T

PubMed Link: 35901280

Variant Present in the following documents:

• BLOODA_ADV-2021-006845-mmc1.xlsx, sheet 2

View BVdb publication page

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Exploiting gene dependency to inform drug development for multiple myeloma.

Scientific Reports

Went, Molly M; Hoang, Phuc H PH; Law, Philip J PJ; Kaiser, Martin F MF; Houlston, Richard S RS

Publication Date: 2022-07-26

Variant appearance in text: NRAS: A146T

PubMed Link: 35882937

Variant Present in the following documents:

• 41598_2022_16940_MOESM2_ESM.xlsx, sheet 8

View BVdb publication page

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Integrative molecular profiling identifies two molecularly and clinically distinct subtypes of blastic plasmacytoid dendritic cell neoplasm.

Blood Cancer Journal

Künstner, Axel A; Schwarting, Julian J; Witte, Hanno M HM; Bernard, Veronica V; Stölting, Stephanie S; Kusch, Kathrin K; Nagarathinam, Kumar K; von Bubnoff, Nikolas N; Murga Penas, Eva Maria EM; Merz, Hartmut H; Busch, Hauke H; Feller, Alfred C AC; Gebauer, Niklas N

Publication Date: 2022-07-04

Variant appearance in text: NRAS: A146T

PubMed Link: 35788129

Variant Present in the following documents:

• 41408_2022_699_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Integrated genomic analyses of acral and mucosal melanomas nominate novel driver genes.

Genome Medicine

Wang, Meng M; Banik, Ishani I; Shain, A Hunter AH; Yeh, Iwei I; Bastian, Boris C BC

Publication Date: 2022-06-16

Variant appearance in text: NRAS: A146T

PubMed Link: 35706047

Variant Present in the following documents:

• 13073_2022_1068_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Rare presentation of multiple thromboses in Erdheim-Chester disease: a case-based review.

International Journal Of Hematology

Liu, Yongchang Y; Huang, Changpin C; Meng, Xiaohu X; Fang, Xin X; Xie, Xupin X; Wang, Changrong C; Wang, Meiyun M

Publication Date: 2022-11

Variant appearance in text: NRAS: A146T

PubMed Link: 35687294

Variant Present in the following documents:

• Main text
• 12185_2022_Article_3393.pdf

View BVdb publication page

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A phase I/II study of ivaltinostat combined with gemcitabine and erlotinib in patients with untreated locally advanced or metastatic pancreatic adenocarcinoma.

International Journal Of Cancer

Jo, Jung Hyun JH; Jung, Dawoon E DE; Lee, Hee Seung HS; Park, Soo Been SB; Chung, Moon Jae MJ; Park, Jeong Youp JY; Bang, Seungmin S; Park, Seung Woo SW; Cho, Sangsook S; Song, Si Young SY

Publication Date: 2022-11-01

Variant appearance in text: NRAS: A146T

PubMed Link: 35657348

Variant Present in the following documents:

• IJC-151-1565-s001.pdf

View BVdb publication page

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Pathophysiologic and clinical implications of molecular profiles resultant from deletion 5q.

Ebiomedicine

Adema, Vera V; Palomo, Laura L; Walter, Wencke W; Mallo, Mar M; Hutter, Stephan S; La Framboise, Thomas T; Arenillas, Leonor L; Meggendorfer, Manja M; Radivoyevitch, Tomas T; Xicoy, Blanca B; Pellagatti, Andrea A; Haferlach, Claudia C; Boultwood, Jacqueline J; Kern, Wolfgang W; Visconte, Valeria V; Sekeres, Mikkael M; Barnard, John J; Haferlach, Torsten T; Solé, Francesc F; Maciejewski, Jaroslaw P JP

Publication Date: 2022-06

Variant appearance in text: NRAS: 436G>A; Ala146Thr

PubMed Link: 35617825

Variant Present in the following documents:

• mmc3.xlsx, sheet 1

View BVdb publication page

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Pediatric T-ALL type-1 and type-2 relapses develop along distinct pathways of clonal evolution.

Leukemia

Richter-Pechańska, Paulina P; Kunz, Joachim B JB; Rausch, Tobias T; Erarslan-Uysal, Büşra B; Bornhauser, Beat B; Frismantas, Viktoras V; Assenov, Yassen Y; Zimmermann, Martin M; Happich, Margit M; von Knebel-Doeberitz, Caroline C; von Neuhoff, Nils N; Köhler, Rolf R; Stanulla, Martin M; Schrappe, Martin M; Cario, Gunnar G; Escherich, Gabriele G; Kirschner-Schwabe, Renate R; Eckert, Cornelia C; Avigad, Smadar S; Pfister, Stefan M SM; Muckenthaler, Martina U MU; Bourquin, Jean-Pierre JP; Korbel, Jan O JO; Kulozik, Andreas E AE

Publication Date: 2022-07

Variant appearance in text: NRAS: A146T

PubMed Link: 35585141

Variant Present in the following documents:

• 41375_2022_1587_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Delineating the RAS Conformational Landscape.

Cancer Research

Parker, Mitchell I MI; Meyer, Joshua E JE; Golemis, Erica A EA; Dunbrack, Roland L RL

Publication Date: 2022-07-05

Variant appearance in text: NRAS: A146T

PubMed Link: 35536216

Variant Present in the following documents:

• Main text
• 2485.pdf

View BVdb publication page

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Concurrent RAS and RAS/BRAF V600E Variants in Colorectal Cancer: More Frequent Than Expected? A Case Report.

Frontiers In Oncology

Zelli, Veronica V; Parisi, Alessandro A; Patruno, Leonardo L; Cannita, Katia K; Ficorella, Corrado C; Luzi, Carla C; Compagnoni, Chiara C; Zazzeroni, Francesca F; Alesse, Edoardo E; Tessitore, Alessandra A

Publication Date: 2022

Variant appearance in text: NRAS: 436G>A

PubMed Link: 35463316

Variant Present in the following documents:

• Main text
• fonc-12-863639.pdf

View BVdb publication page

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Validation of a small molecule inhibitor of PDE6D-RAS interaction with favorable anti-leukemic effects.

Blood Cancer Journal

Canovas Nunes, Sara S; De Vita, Serena S; Anighoro, Andrew A; Autelitano, François F; Beaumont, Edward E; Klingbeil, Pamela P; McGuinness, Meaghan M; Duvert, Beatrice B; Harris, Chad C; Yang, Lu L; Pokharel, Sheela Pangeni SP; Chen, Chun-Wei CW; Ermann, Monika M; Williams, David A DA; Xu, Haiming H

Publication Date: 2022-04-14

Variant appearance in text: NRAS: A146T

PubMed Link: 35422065

Variant Present in the following documents:

• 41408_2022_Article_663.pdf

View BVdb publication page

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Integrated genomic analyses identify high-risk factors and actionable targets in T-cell acute lymphoblastic leukemia.

Blood Science (Baltimore, Md.)

Zhu, Haichuan H; Dong, Bingjie B; Zhang, Yingchi Y; Wang, Mei M; Rao, Jianan J; Cui, Bowen B; Liu, Yu Y; Jiang, Qian Q; Wang, Weitao W; Yang, Lu L; Yu, Anqi A; Li, Zongru Z; Liu, Chao C; Zhang, Leping L; Huang, Xiaojun X; Zhu, Xiaofan X; Wu, Hong H

Publication Date: 2022-01

Variant appearance in text: NRAS: A146T

PubMed Link: 35399540

Variant Present in the following documents:

• bls-4-16-s005.xlsx, sheet 2
• bls-4-16-s004.pdf

View BVdb publication page

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Distinct genomic landscape of Chinese pediatric acute myeloid leukemia impacts clinical risk classification.

Nature Communications

Liu, Ting T; Rao, Jianan J; Hu, Wenting W; Cui, Bowen B; Cai, Jiaoyang J; Liu, Yuhan Y; Sun, Huiying H; Chen, Xiaoxiao X; Tang, Yanjing Y; Chen, Jing J; Wang, Xiang X; Wang, Han H; Qian, Wubin W; Mao, Binchen B; Guo, Sheng S; Wang, Ronghua R; Liu, Yu Y; Shen, Shuhong S

Publication Date: 2022-03-28

Variant appearance in text: NRAS: A146T

PubMed Link: 35347147

Variant Present in the following documents:

• 41467_2022_29336_MOESM8_ESM.xlsx, sheet 1

View BVdb publication page

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Effects of NRAS Mutations on Leukemogenesis and Targeting of Children With Acute Lymphoblastic Leukemia.

Frontiers In Cell And Developmental Biology

Qian, Jiabi J; Li, Zifeng Z; Pei, Kunlin K; Li, Ziping Z; Li, Chunjie C; Yan, Muxia M; Qian, Maoxiang M; Song, Yuanbin Y; Zhang, Hui H; He, Yingyi Y

Publication Date: 2022

Variant appearance in text: NRAS: A146T

PubMed Link: 35211470

Variant Present in the following documents:

• DataSheet2.xlsx, sheet 8

View BVdb publication page

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Sensitive Quantification of Cell-Free Tumor DNA for Early Detection of Recurrence in Colorectal Cancer.

Frontiers In Genetics

Stasik, Sebastian S; Mende, Marika M; Schuster, Caroline C; Mahler, Sandra S; Aust, Daniela D; Tannapfel, Andrea A; Reinacher-Schick, Anke A; Baretton, Gustavo G; Krippendorf, Claudia C; Bornhäuser, Martin M; Ehninger, Gerhard G; Folprecht, Gunnar G; Thiede, Christian C

Publication Date: 2021

Variant appearance in text: NRAS: 436G>A; Ala146Thr

PubMed Link: 35069704

Variant Present in the following documents:

• fgene-12-811291.pdf

View BVdb publication page

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Fusobacterium nucleatum and Bacteroides fragilis detection in colorectal tumours: Optimal target site and correlation with total bacterial load.

Plos One

Rye, Marie S MS; Garrett, Kerryn L KL; Holt, Robert A RA; Platell, Cameron F CF; McCoy, Melanie J MJ

Publication Date: 2022

Variant appearance in text: NRAS: A146T

PubMed Link: 34995318

Variant Present in the following documents:

• Main text
• pone.0262416.pdf

View BVdb publication page

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Fusobacterium nucleatum and Bacteroides fragilis detection in colorectal tumours: Optimal target site and correlation with total bacterial load.

Plos One

Rye, Marie S MS; Garrett, Kerryn L KL; Holt, Robert A RA; Platell, Cameron F CF; McCoy, Melanie J MJ

Publication Date: 2022

Variant appearance in text: NRAS: A146T

PubMed Link: 34995318

Variant Present in the following documents:

• Main text
• pone.0262416.pdf

View BVdb publication page

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Genetic Landscape of Relapsed and Refractory Diffuse Large B-Cell Lymphoma: A Systemic Review and Association Analysis With Next-Generation Sequencing.

Frontiers In Genetics

Gao, Fan F; Tian, Lei L; Shi, Hui H; Zheng, Peihao P; Wang, Jing J; Dong, Fei F; Hu, Kai K; Ke, Xiaoyan X

Publication Date: 2021

Variant appearance in text: NRAS: 436G>A; A146T

PubMed Link: 34925435

Variant Present in the following documents:

• DataSheet2.xlsx, sheet 1

View BVdb publication page

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Concordance of acquired mutations between metastatic lesions and liquid biopsy in metastatic colorectal cancer.

Future Science Oa

Taniguchi, Fumitaka F; Nyuya, Akihiro A; Toshima, Toshiaki T; Yasui, Kazuya K; Mori, Yoshiko Y; Okawaki, Makoto M; Kishimoto, Hiroyuki H; Umeda, Yuzo Y; Fujiwara, Toshiyoshi T; Tanioka, Hiroaki H; Yamaguchi, Yoshiyuki Y; Goel, Ajay A; Nagasaka, Takeshi T

Publication Date: 2021-12

Variant appearance in text: NRAS: A146T

PubMed Link: 34840814

Variant Present in the following documents:

• Main text
• fsoa-07-757-s2.xlsx, sheet 1
• fsoa-07-757-s3.xlsx, sheet 1

View BVdb publication page

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Integrative Genomic Analysis of Pediatric Myeloid-Related Acute Leukemias Identifies Novel Subtypes and Prognostic Indicators.

Blood Cancer Discovery

Fornerod, Maarten M; Ma, Jing J; Noort, Sanne S; Liu, Yu Y; Walsh, Michael P MP; Shi, Lei L; Nance, Stephanie S; Liu, Yanling Y; Wang, Yuanyuan Y; Song, Guangchun G; Lamprecht, Tamara T; Easton, John J; Mulder, Heather L HL; Yergeau, Donald D; Myers, Jacquelyn J; Kamens, Jennifer L JL; Obeng, Esther A EA; Pigazzi, Martina M; Jarosova, Marie M; Kelaidi, Charikleia C; Polychronopoulou, Sophia S; Lamba, Jatinder K JK; Baker, Sharyn D SD; Rubnitz, Jeffrey E JE; Reinhardt, Dirk D; van den Heuvel-Eibrink, Marry M MM; Locatelli, Franco F; Hasle, Henrik H; Klco, Jeffery M JM; Downing, James R JR; Zhang, Jinghui J; Pounds, Stanley S; Zwaan, C Michel CM; Gruber, Tanja A TA; , ; , ; , ; , ; , ; ,

Publication Date: 2021-11

Variant appearance in text: NRAS: A146T

PubMed Link: 34778799

Variant Present in the following documents:

• bloodcandisc-2-586-s001.xlsx, sheet 11

View BVdb publication page

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Individualized Proteogenomics Reveals the Mutational Landscape of Melanoma Patients in Response to Immunotherapy.

Cancers

Schmitt, Marisa M; Sinnberg, Tobias T; Niessner, Heike H; Forschner, Andrea A; Garbe, Claus C; Macek, Boris B; Nalpas, Nicolas C NC

Publication Date: 2021-10-28

Variant appearance in text: NRAS: A146T

PubMed Link: 34771574

Variant Present in the following documents:

• Main text
• cancers-13-05411.pdf

View BVdb publication page

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Multiple Myeloma Cells Depend on the DDI2/NRF1-mediated Proteasome Stress Response for Survival.

Blood Advances

Chen, Tianzeng T; Ho, Matthew M; Briere, Jenna J; Moscvin, Maria M; Czarnecki, Peter G PG; Anderson, Kenneth C KC; Blackwell, T Keith TK; Bianchi, Giada G

Publication Date: 2021-10-14

Variant appearance in text: NRAS: A146T

PubMed Link: 34649278

Variant Present in the following documents:

• Main text

View BVdb publication page

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Multiple myeloma cells depend on the DDI2/NRF1-mediated proteasome stress response for survival.

Blood Advances

Chen, Tianzeng T; Ho, Matthew M; Briere, Jenna J; Moscvin, Maria M; Czarnecki, Peter G PG; Anderson, Kenneth C KC; Blackwell, T Keith TK; Bianchi, Giada G

Publication Date: 2022-01-25

Variant appearance in text: NRAS: A146T

PubMed Link: 34649278

Variant Present in the following documents:

• Main text

View BVdb publication page

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Molecular and functional profiling identifies therapeutically targetable vulnerabilities in plasmablastic lymphoma.

Nature Communications

Frontzek, Fabian F; Staiger, Annette M AM; Zapukhlyak, Myroslav M; Xu, Wendan W; Bonzheim, Irina I; Borgmann, Vanessa V; Sander, Philip P; Baptista, Maria Joao MJ; Heming, Jan-Niklas JN; Berning, Philipp P; Wullenkord, Ramona R; Erdmann, Tabea T; Lutz, Mathias M; Veratti, Pia P; Ehrenfeld, Sophia S; Wienand, Kirsty K; Horn, Heike H; Goodlad, John R JR; Wilson, Matthew R MR; Anagnostopoulos, Ioannis I; Lamping, Mario M; Gonzalez-Barca, Eva E; Climent, Fina F; Salar, Antonio A; Castellvi, Josep J; Abrisqueta, Pau P; Menarguez, Javier J; Aldamiz, Teresa T; Richter, Julia J; Klapper, Wolfram W; Tzankov, Alexandar A; Dirnhofer, Stefan S; Rosenwald, Andreas A; Mate, José Luis JL; Tapia, Gustavo G; Lenz, Peter P; Miething, Cornelius C; Hartmann, Wolfgang W; Chapuy, Björn B; Fend, Falko F; Ott, German G; Navarro, José-Tomas JT; Grau, Michael M; Lenz, Georg G

Publication Date: 2021-08-31

Variant appearance in text: NRAS: 436G>A; A146T

PubMed Link: 34465776

Variant Present in the following documents:

• 41467_2021_25405_MOESM9_ESM.xlsx, sheet 1

View BVdb publication page

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Pretreatment 18F-FDG PET/CT Imaging Predicts the KRAS/NRAS/BRAF Gene Mutational Status in Colorectal Cancer.

Journal Of Oncology

He, Peng P; Zou, Yuan Y; Qiu, Jia J; Yang, Tianhong T; Peng, Lei L; Zhang, Xiangsong X

Publication Date: 2021

Variant appearance in text: NRAS: Ala146Thr

PubMed Link: 34239564

Variant Present in the following documents:

• Main text

View BVdb publication page

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Predictive and Prognostic Value of BRAF and NRAS Mutation of 159 Sentinel Lymph Node Cases in Melanoma-A Retrospective Single-Institute Study.

Cancers

Liszkay, Gabriella G; Mátrai, Zoltán Z; Czirbesz, Kata K; Jani, Nóra N; Bencze, Eszter E; Kenessey, István I

Publication Date: 2021-06-30

Variant appearance in text: NRAS: A146T

PubMed Link: 34209415

Variant Present in the following documents:

• Main text
• cancers-13-03302.pdf

View BVdb publication page

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NRAS Mutations May Be Involved in the Pathogenesis of Cutaneous Rosai Dorfman Disease: A Pilot Study.

Biology

Wu, Kuan-Jou KJ; Li, Shu-Hao SH; Liao, Jia-Bin JB; Chiou, Chien-Chun CC; Wu, Chieh-Shan CS; Chen, Chien-Chin CC

Publication Date: 2021-05-02

Variant appearance in text: NRAS: A146T

PubMed Link: 34063325

Variant Present in the following documents:

• Main text

View BVdb publication page

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JunB is a key regulator of multiple myeloma bone marrow angiogenesis.

Leukemia

Fan, Fengjuan F; Malvestiti, Stefano S; Vallet, Sonia S; Lind, Judith J; Garcia-Manteiga, Jose Manuel JM; Morelli, Eugenio E; Jiang, Qinyue Q; Seckinger, Anja A; Hose, Dirk D; Goldschmidt, Hartmut H; Stadlbauer, Andreas A; Sun, Chunyan C; Mei, Heng H; Pecherstorfer, Martin M; Bakiri, Latifa L; Wagner, Erwin F EF; Tonon, Giovanni G; Sattler, Martin M; Hu, Yu Y; Tassone, Pierfrancesco P; Jaeger, Dirk D; Podar, Klaus K

Publication Date: 2021-12

Variant appearance in text: NRAS: A146T

PubMed Link: 34007044

Variant Present in the following documents:

• 41375_2021_1271_MOESM1_ESM.pdf

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Mutation status and prognostic value of KRAS and NRAS mutations in Moroccan colon cancer patients: A first report.

Plos One

El Agy, Fatima F; El Bardai, Sanae S; El Otmani, Ihsane I; Benbrahim, Zineb Z; Karim, Ibn Majdoub Hassani MH; Mazaz, Khalid K; Benjelloun, El Bachir EB; Ousadden, Abdelmalek A; El Abkari, Mohammed M; Ibrahimi, Sidi Adil SA; Chbani, Laila L

Publication Date: 2021

Variant appearance in text: NRAS: 436G>A

PubMed Link: 33784337

Variant Present in the following documents:

• pone.0248522.pdf

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: NRAS: 436G>A; A146T

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: NRAS: 436G>A; A146T

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM10_ESM.xlsx, sheet 1

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Circulating Methylated DNA to Monitor the Dynamics of RAS Mutation Clearance in Plasma from Metastatic Colorectal Cancer Patients.

Cancers

Nicolazzo, Chiara C; Barault, Ludovic L; Caponnetto, Salvatore S; Macagno, Marco M; De Renzi, Gianluigi G; Gradilone, Angela A; Belardinilli, Francesca F; Cortesi, Enrico E; Di Nicolantonio, Federica F; Gazzaniga, Paola P

Publication Date: 2020-12-04

Variant appearance in text: NRAS: A146T

PubMed Link: 33291569

Variant Present in the following documents:

• Main text
• cancers-12-03633.pdf

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Multiclonal complexity of pediatric acute lymphoblastic leukemia and the prognostic relevance of subclonal mutations

Haematologica

Antić, Željko Ž; Yu, Jiangyan J; Van Reijmersdal, Simon V SV; Van Dijk, Anke A; Dekker, Linde L; Segerink, Wouter H WH; Sonneveld, Edwin E; Fiocco, Marta M; Pieters, Rob R; Hoogerbrugge, Peter M PM; Van Leeuwen, Frank N FN; Van Kessel, Ad Geurts AG; Waanders, Esme E; Kuiper, Roland P RP

Publication Date: 2021-12-01

Variant appearance in text: NRAS: A146T

PubMed Link: 33147938

Variant Present in the following documents:

• 2020_259226_ANTIC_SUPPL_TABLES.xlsx, sheet 3

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Multiclonal complexity of pediatric acute lymphoblastic leukemia and the prognostic relevance of subclonal mutations

Haematologica

Antić, Željko Ž; Yu, Jiangyan J; Van Reijmersdal, Simon V SV; Van Dijk, Anke A; Dekker, Linde L; Segerink, Wouter H WH; Sonneveld, Edwin E; Fiocco, Marta M; Pieters, Rob R; Hoogerbrugge, Peter M PM; Van Leeuwen, Frank N FN; Van Kessel, Ad Geurts AG; Waanders, Esme E; Kuiper, Roland P RP

Publication Date: 2021-12-01

Variant appearance in text: NRAS: A146T

PubMed Link: 33147938

Variant Present in the following documents:

• 2020_259226_ANTIC_SUPPL_TABLES.xlsx, sheet 3

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NGS for (Hemato-) Oncology in Belgium: Evaluation of Laboratory Performance and Feasibility of a National External Quality Assessment Program.

Cancers

Delcourt, Thomas T; Vanneste, Kevin K; Soumali, Mohamed Rida MR; Coucke, Wim W; Ghislain, Vanessa V; Hebrant, Aline A; Van Valckenborgh, Els E; De Keersmaecker, Sigrid C J SCJ; Roosens, Nancy H NH; Van De Walle, Philippe P; Van Den Bulcke, Marc M; Antoniou, Aline A

Publication Date: 2020-10-29

Variant appearance in text: NRAS: Ala146Thr

PubMed Link: 33138022

Variant Present in the following documents:

• cancers-12-03180.pdf

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Expanded Low Allele Frequency RAS and BRAF V600E Testing in Metastatic Colorectal Cancer as Predictive Biomarkers for Cetuximab in the Randomized CO.17 Trial.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Loree, Jonathan M JM; Dowers, Anthony A; Tu, Dongsheng D; Jonker, Derek J DJ; Edelstein, Daniel L DL; Quinn, Hannah H; Holtrup, Frank F; Price, Timothy T; Zalcberg, John R JR; Moore, Malcolm J MJ; Karapetis, Christos S CS; O'Callaghan, Chris J CJ; Waring, Paul P; Kennecke, Hagen F HF; Hamilton, Stanley R SR; Kopetz, Scott S

Publication Date: 2021-01-01

Variant appearance in text: NRAS: A146T

PubMed Link: 33087330

Variant Present in the following documents:

• Main text

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Validation and clinical application of a targeted next-generation sequencing gene panel for solid and hematologic malignancies.

Peerj

Prieto-Potin, Iván I; Carvajal, Nerea N; Plaza-Sánchez, Jenifer J; Manso, Rebeca R; Aúz-Alexandre, Carmen Laura CL; Chamizo, Cristina C; Zazo, Sandra S; López-Sánchez, Almudena A; Rodríguez-Pinilla, Socorro María SM; Camacho, Laura L; Longarón, Raquel R; Bellosillo, Beatriz B; Somoza, Rosa R; Hernández-Losa, Javier J; Fernández-Soria, Víctor Manuel VM; Ramos-Ruiz, Ricardo R; Cristóbal, Ion I; García-Foncillas, Jesús J; Rojo, Federico F

Publication Date: 2020

Variant appearance in text: NRAS: 436G>A; A146T

PubMed Link: 33083132

Variant Present in the following documents:

• peerj-08-10069-s007.xlsx, sheet 1

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Clinicopathological characteristics and mutational profile of KRAS and NRAS in Tunisian patients with sporadic colorectal cancer

Turkish Journal Of Medical Sciences

Ounissi, Donia D; Weslati, Marwa M; Boughriba, Rahma R; Hazgui, Meriam M; Bouraoui, Saadia S

Publication Date: 2021-02-26

Variant appearance in text: NRAS: A146T

PubMed Link: 32892548

Variant Present in the following documents:

• Main text
• turkjmedsci-51-148.pdf

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The effects of mutant Ras proteins on the cell signalome.

Cancer Metastasis Reviews

Takács, Tamás T; Kudlik, Gyöngyi G; Kurilla, Anita A; Szeder, Bálint B; Buday, László L; Vas, Virag V

Publication Date: 2020-12

Variant appearance in text: NRAS: A146T

PubMed Link: 32648136

Variant Present in the following documents:

• 10555_2020_Article_9912.pdf

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A novel NGS-based microsatellite instability (MSI) status classifier with 9 loci for colorectal cancer patients.

Journal Of Translational Medicine

Zheng, Kai K; Wan, Hua H; Zhang, Jie J; Shan, Guangyu G; Chai, Ningning N; Li, Dongdong D; Fang, Nan N; Liu, Lina L; Zhang, Jingbo J; Du, Rong R; Wu, Qixi Q; Li, Xichuan X; Zhang, Chunze C

Publication Date: 2020-05-28

Variant appearance in text: NRAS: A146T

PubMed Link: 32466784

Variant Present in the following documents:

• 12967_2020_Article_2373.pdf

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RAS Mutational Status Detection in Tissue, Plasma, and Stool Samples for Colorectal Cancer.

Biomed Research International

Zhu, Liuying L; Wang, Yuanhe Y; Zhou, Yang Y; Dong, Qian Q; Liu, Yunpeng Y; Zhang, Jingdong J

Publication Date: 2020

Variant appearance in text: NRAS: A146T

PubMed Link: 32351996

Variant Present in the following documents:

• Main text
• BMRI2020-5419634.pdf

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Prognostic implications of EGFR protein expression in sporadic colorectal tumors: Correlation with copy number status, mRNA levels and miRNA regulation.

Scientific Reports

Del Carmen, Sofía S; Corchete, Luís Antonio LA; Gervas, Ruth R; Rodriguez, Alba A; Garcia, María M; Álcazar, José Antonio JA; García, Jacinto J; Bengoechea, Oscar O; Muñoz-Bellvis, Luis L; Sayagués, José María JM; Abad, Mar M

Publication Date: 2020-03-13

Variant appearance in text: NRAS: A146T

PubMed Link: 32170146

Variant Present in the following documents:

• Main text

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Genetic mutational analysis of pediatric acute lymphoblastic leukemia from a single center in China using exon sequencing.

Bmc Cancer

Zhang, Honghong H; Wang, Hongsheng H; Qian, Xiaowen X; Gao, Shuai S; Xia, Jieqi J; Liu, Junwen J; Cheng, Yanqin Y; Man, Jie J; Zhai, Xiaowen X

Publication Date: 2020-03-12

Variant appearance in text: NRAS: A146T

PubMed Link: 32164600

Variant Present in the following documents:

• Main text

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Analysis of Molecular Pretreated Tumor Profiles as Predictive Biomarkers of Therapeutic Response and Survival Outcomes after Neoadjuvant Therapy for Rectal Cancer in Moroccan Population.

Disease Markers

El Otmani, Ihsane I; El Agy, Fatima F; El Baradai, Sanae S; Bouguenouch, Laila L; Lahmidani, Nada N; El Abkari, Mohammed M; Benajah, Dafr Allah DA; Toughrai, Imane I; El Bouhaddouti, Hicham H; Mouaqit, Ouadii O; Ibn Majdoub Hassani, Karim K; Mazaz, Khalid K; Benjelloun, El Bachir EB; Ousadden, Abdelmalek A; El Rhazi, Karima K; Bouhafa, Touria T; Benbrahim, Zineb Z; Ouldim, Karim K; Ibrahimi, Sidi Adil SA; Ait Taleb, Khalid K; Chbani, Laila L

Publication Date: 2020

Variant appearance in text: NRAS: A146T

PubMed Link: 31998419

Variant Present in the following documents:

• DM2020-8459303.pdf

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First Glance of Molecular Profile of Atypical Cellular Angiofibroma/Cellular Angiofibroma with Sarcomatous Transformation by Next Generation Sequencing.

Diagnostics (Basel, Switzerland)

Chien, Yi-Che Chang YC; Mokánszki, Attila A; Huang, Hsuan-Ying HY; Geronimo Silva, Raimundo R; Chen, Chien-Chin CC; Beke, Lívia L; Mónus, Anikó A; Méhes, Gábor G

Publication Date: 2020-01-09

Variant appearance in text: NRAS: 436G>A; Ala146Thr

PubMed Link: 31936598

Variant Present in the following documents:

• Main text

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