NRAS c.425T>C ;(p.I142T)

Variant ID: 1-115252215-A-G

NM_002524.4(NRAS):c.425T>C;(p.I142T)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Identifying Actionable Variants Using Capture-Based Targeted Sequencing in 563 Patients With Non-Small Cell Lung Carcinoma.

Frontiers In Oncology
Jiang, Haiping H; Wang, Yinan Y; Xu, Hanlin H; Lei, Wei W; Yu, Xiaoyun X; Tian, Haiying H; Meng, Cong C; Wang, Xueying X; Zhao, Zicheng Z; Jin, Xiangfeng X
Publication Date: 2021

Variant appearance in text: NRAS: I142T; rs758898839
PubMed Link: 35186718
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Clinical and molecular characteristics of Chinese non-small cell lung cancer patients with ERBB2 transmembrane domain mutations.

Molecular Oncology
Fan, Yun Y; Qiu, Jinrong J; Yu, Ruoying R; Cao, Ran R; Chen, Xiaoxi X; Ou, Qiuxiang Q; Wu, Xue X; Shao, Yang W YW; Nagasaka, Misako M; Zhang, Jiexia J; Ou, Sai-Hong Ignatius SI
Publication Date: 2020-08

Variant appearance in text: NRAS: 425T>C; I142T
PubMed Link: 32478891
Variant Present in the following documents:
  • MOL2-14-1731-s002.xlsx, sheet 1
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: NRAS: I142T
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 1
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page