NRAS c.351G>T ;(p.K117N)

Variant ID: 1-115252289-C-A

NM_002524.4(NRAS):c.351G>T;(p.K117N)

This variant was identified in 36 publications

View GRCh38 version.




Publications:


Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Publication Date: 2023-04-03

Variant appearance in text: NRAS: K117N
PubMed Link: 37012232
Variant Present in the following documents:
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
View BVdb publication page



Rosai-Dorfman Disease between Proliferation and Neoplasia.

Cancers
Elbaz Younes, Ismail I; Sokol, Lubomir L; Zhang, Ling L
Publication Date: 2022-10-27

Variant appearance in text: NRAS: K117N
PubMed Link: 36358690
Variant Present in the following documents:
  • cancers-14-05271.pdf
View BVdb publication page



Prevalence and patterns of mutations in RAS/RAF/MEK/ERK/MAPK signaling pathway in colorectal cancer in North Africa.

Bmc Cancer
Jafari, Meryem M; Laraqui, Abdelilah A; Baba, Walid W; Benmokhtar, Soukaina S; Zaitouni, Sara El SE; Ali, Abdelmounaim Ait AA; Bounaim, Ahmed A; Moujahid, Mountassir M; Tanz, Rachid R; Mahfoud, Tarik T; Sbitti, Yassir Y; Annaz, Hicham El HE; Abi, Rachid R; Tagajdid, Mohamed Rida MR; Kochri, Safae El SE; Lahlou, Idriss Amine IA; Hsaini, Houda El HE; Belayachi, Lamiae L; Benjouad, Abdelaziz A; Ichou, Mohammed M; En-Nya, Amina A; Ennibi, Khalid K
Publication Date: 2022-11-07

Variant appearance in text: NRAS: 351G>T; K117N
PubMed Link: 36344948
Variant Present in the following documents:
  • 12885_2022_Article_10235.pdf
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The kinetics of blast clearance are associated with copy number alterations in childhood B-cell acute lymphoblastic leukemia.

Neoplasia (New York, N.Y.)
Urbańska, Zuzanna Z; Lejman, Monika M; Taha, Joanna J; Madzio, Joanna J; Ostrowska, Kinga K; Miarka-Walczyk, Karolina K; Wypyszczak, Kamila K; Styka, Borys B; Jakubowska, Justyna J; Sędek, Łukasz Ł; Szczepański, Tomasz T; Stańczak, Marcin M; Fendler, Wojciech W; Młynarski, Wojciech W; Pastorczak, Agata A
Publication Date: 2022-10-23

Variant appearance in text: NRAS: Lys117Asn
PubMed Link: 36288679
Variant Present in the following documents:
  • mmc1.pdf
View BVdb publication page



Performance of Idylla™ RAS-BRAF mutation test for formalin-fixed paraffin-embedded tissues of colorectal cancer.

International Journal Of Clinical Oncology
Makutani, Yusuke Y; Sakai, Kazuko K; Yamada, Masahiro M; Wada, Toshiaki T; Chikugo, Takaaki T; Satou, Takao T; Iwasa, Yoko Y; Yamamoto, Hidekazu H; de Velasco, Marco A MA; Nishio, Kazuto K; Kawamura, Junichiro J
Publication Date: 2022-07

Variant appearance in text: NRAS: 351G>T; K117N
PubMed Link: 35474548
Variant Present in the following documents:
  • Main text
  • 10147_2022_Article_2167.pdf
View BVdb publication page



Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia.

Signal Transduction And Targeted Therapy
Zhang, Qi Q; Riley-Gillis, Bridget B; Han, Lina L; Jia, Yannan Y; Lodi, Alessia A; Zhang, Haijiao H; Ganesan, Saravanan S; Pan, Rongqing R; Konoplev, Sergej N SN; Sweeney, Shannon R SR; Ryan, Jeremy A JA; Jitkova, Yulia Y; Dunner, Kenneth K; Grosskurth, Shaun E SE; Vijay, Priyanka P; Ghosh, Sujana S; Lu, Charles C; Ma, Wencai W; Kurtz, Stephen S; Ruvolo, Vivian R VR; Ma, Helen H; Weng, Connie C CC; Ramage, Cassandra L CL; Baran, Natalia N; Shi, Ce C; Cai, Tianyu T; Davis, Richard Eric RE; Battula, Venkata L VL; Mi, Yingchang Y; Wang, Jing J; DiNardo, Courtney D CD; Andreeff, Michael M; Tyner, Jeffery W JW; Schimmer, Aaron A; Letai, Anthony A; Padua, Rose Ann RA; Bueso-Ramos, Carlos E CE; Tiziani, Stefano S; Leverson, Joel J; Popovic, Relja R; Konopleva, Marina M
Publication Date: 2022-02-21

Variant appearance in text: NRAS: 351G>T; Lys117Asn
PubMed Link: 35185150
Variant Present in the following documents:
  • 41392_2021_870_MOESM1_ESM.pdf
View BVdb publication page



Concordance of acquired mutations between metastatic lesions and liquid biopsy in metastatic colorectal cancer.

Future Science Oa
Taniguchi, Fumitaka F; Nyuya, Akihiro A; Toshima, Toshiaki T; Yasui, Kazuya K; Mori, Yoshiko Y; Okawaki, Makoto M; Kishimoto, Hiroyuki H; Umeda, Yuzo Y; Fujiwara, Toshiyoshi T; Tanioka, Hiroaki H; Yamaguchi, Yoshiyuki Y; Goel, Ajay A; Nagasaka, Takeshi T
Publication Date: 2021-12

Variant appearance in text: NRAS: K117N
PubMed Link: 34840814
Variant Present in the following documents:
  • Main text
View BVdb publication page



Clinicopathological characteristics and mutational profile of KRAS and NRAS in Tunisian patients with sporadic colorectal cancer

Turkish Journal Of Medical Sciences
Ounissi, Donia D; Weslati, Marwa M; Boughriba, Rahma R; Hazgui, Meriam M; Bouraoui, Saadia S
Publication Date: 2021-02-26

Variant appearance in text: NRAS: K117N
PubMed Link: 32892548
Variant Present in the following documents:
  • Main text
  • turkjmedsci-51-148.pdf
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KRAS, NRAS, and BRAF mutation prevalence, clinicopathological association, and their application in a predictive model in Mexican patients with metastatic colorectal cancer: A retrospective cohort study.

Plos One
Sanchez-Ibarra, Hector Eduardo HE; Jiang, Xianli X; Gallegos-Gonzalez, Elena Yareli EY; Cavazos-González, Adriana Carolina AC; Chen, Yenho Y; Morcos, Faruck F; Barrera-Saldaña, Hugo Alberto HA
Publication Date: 2020

Variant appearance in text: NRAS: K117N
PubMed Link: 32628708
Variant Present in the following documents:
  • Main text
  • pone.0235490.pdf
View BVdb publication page



Prognostic implications of EGFR protein expression in sporadic colorectal tumors: Correlation with copy number status, mRNA levels and miRNA regulation.

Scientific Reports
Del Carmen, Sofía S; Corchete, Luís Antonio LA; Gervas, Ruth R; Rodriguez, Alba A; Garcia, María M; Álcazar, José Antonio JA; García, Jacinto J; Bengoechea, Oscar O; Muñoz-Bellvis, Luis L; Sayagués, José María JM; Abad, Mar M
Publication Date: 2020-03-13

Variant appearance in text: NRAS: K117N
PubMed Link: 32170146
Variant Present in the following documents:
  • Main text
  • 41598_2020_Article_61688.pdf
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Standardization of Somatic Variant Classifications in Solid and Haematological Tumours by a Two-Level Approach of Biological and Clinical Classes: An Initiative of the Belgian ComPerMed Expert Panel.

Cancers
Froyen, Guy G; Le Mercier, Marie M; Lierman, Els E; Vandepoele, Karl K; Nollet, Friedel F; Boone, Elke E; Van der Meulen, Joni J; Jacobs, Koen K; Lambin, Suzan S; Vander Borght, Sara S; Van Valckenborgh, Els E; Antoniou, Aline A; Hébrant, Aline A
Publication Date: 2019-12-16

Variant appearance in text: NRAS: K117N
PubMed Link: 31888289
Variant Present in the following documents:
  • Main text
  • cancers-11-02030.pdf
View BVdb publication page



A large peptidome dataset improves HLA class I epitope prediction across most of the human population.

Nature Biotechnology
Sarkizova, Siranush S; Klaeger, Susan S; Le, Phuong M PM; Li, Letitia W LW; Oliveira, Giacomo G; Keshishian, Hasmik H; Hartigan, Christina R CR; Zhang, Wandi W; Braun, David A DA; Ligon, Keith L KL; Bachireddy, Pavan P; Zervantonakis, Ioannis K IK; Rosenbluth, Jennifer M JM; Ouspenskaia, Tamara T; Law, Travis T; Justesen, Sune S; Stevens, Jonathan J; Lane, William J WJ; Eisenhaure, Thomas T; Lan Zhang, Guang G; Clauser, Karl R KR; Hacohen, Nir N; Carr, Steven A SA; Wu, Catherine J CJ; Keskin, Derin B DB
Publication Date: 2020-02

Variant appearance in text: NRAS: K117N
PubMed Link: 31844290
Variant Present in the following documents:
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 38
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 23
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 8
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 32
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 25
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 24
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 90
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Evaluation of KRAS, NRAS and BRAF hotspot mutations detection for patients with metastatic colorectal cancer using direct DNA pipetting in a fully-automated platform and Next-Generation Sequencing for laboratory workflow optimisation.

Plos One
Gilson, Pauline P; Franczak, Claire C; Dubouis, Ludovic L; Husson, Marie M; Rouyer, Marie M; Demange, Jessica J; Perceau, Marie M; Leroux, Agnès A; Merlin, Jean-Louis JL; Harlé, Alexandre A
Publication Date: 2019

Variant appearance in text: NRAS: 351G>T; Lys117Asn
PubMed Link: 31265477
Variant Present in the following documents:
  • Main text
  • pone.0219204.pdf
View BVdb publication page



KRAS and NRAS pyrosequencing screening in Tunisian colorectal cancer patients in 2015.

Heliyon
Jouini, Raja R; Ferchichi, Marwa M; BenBrahim, Ehsen E; Ayari, Imen I; Khanchel, Fatma F; Koubaa, Wafa W; Saidi, Olfa O; Allani, Riadh R; Chadli-Debbiche, Aschraf A
Publication Date: 2019-03

Variant appearance in text: NRAS: K117N
PubMed Link: 30949599
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Clinical relevance of circulating tumor DNA assessed through deep sequencing in patients with metastatic colorectal cancer.

Cancer Medicine
Osumi, Hiroki H; Shinozaki, Eiji E; Takeda, Yoshinori Y; Wakatsuki, Takeru T; Ichimura, Takashi T; Saiura, Akio A; Yamaguchi, Kensei K; Takahashi, Shunji S; Noda, Tetsuo T; Zembutsu, Hitoshi H
Publication Date: 2019-01

Variant appearance in text: NRAS: K117N
PubMed Link: 30575318
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mutation Status and Immunohistochemical Correlation of KRAS, NRAS, and BRAF in 260 Chinese Colorectal and Gastric Cancers.

Frontiers In Oncology
Yang, Qiwei Q; Huo, Sibo S; Sui, Yujie Y; Du, Zhenwu Z; Zhao, Haiyue H; Liu, Yu Y; Li, Wei W; Wan, Xin X; Liu, Tongjun T; Zhang, Guizhen G
Publication Date: 2018

Variant appearance in text: NRAS: K117N
PubMed Link: 30416987
Variant Present in the following documents:
  • Main text
View BVdb publication page



Clinical Validation of Newly Developed Multiplex Kit Using Luminex xMAP Technology for Detecting Simultaneous RAS and BRAF Mutations in Colorectal Cancer: Results of the RASKET-B Study.

Neoplasia (New York, N.Y.)
Taniguchi, Hiroya H; Okamoto, Wataru W; Muro, Kei K; Akagi, Kiwamu K; Hara, Hiroki H; Nishina, Tomohiro T; Kajiwara, Takeshi T; Denda, Tadamichi T; Hironaka, Shuichi S; Kudo, Toshihiro T; Satoh, Taroh T; Yamanaka, Takeharu T; Abe, Yukiko Y; Fukushima, Yoshiyuki Y; Yoshino, Takayuki T
Publication Date: 2018-12

Variant appearance in text: NRAS: K117N
PubMed Link: 30412858
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach.

Oncotarget
Del Carmen, Sofía S; Sayagués, José María JM; Bengoechea, Oscar O; Anduaga, María Fernanda MF; Alcazar, Jose Antonio JA; Gervas, Ruth R; García, Jacinto J; Orfao, Alberto A; Bellvis, Luis Muñoz LM; Sarasquete, María Eugenia ME; Del Mar Abad, María M
Publication Date: 2018-09-28

Variant appearance in text: NRAS: K117N
PubMed Link: 30344942
Variant Present in the following documents:
  • Main text
View BVdb publication page



Quality and practical aspects of pathological and molecular diagnostics in metastatic colorectal cancer (mCRC).

Contemporary Oncology (Poznan, Poland)
Tysarowski, Andrzej A; Nasierowska-Guttmejer, Anna A
Publication Date: 2018

Variant appearance in text: NRAS: 351G>T; Lys117Asn
PubMed Link: 30150883
Variant Present in the following documents:
  • Main text
  • WO-22-77047.pdf
View BVdb publication page



Japanese Society of Medical Oncology Clinical Guidelines: Molecular Testing for Colorectal Cancer Treatment, Third Edition.

Cancer Science
Yamazaki, Kentaro K; Taniguchi, Hiroya H; Yoshino, Takayuki T; Akagi, Kiwamu K; Ishida, Hideyuki H; Ebi, Hiromichi H; Nakatani, Kaname K; Muro, Kei K; Yatabe, Yasushi Y; Yamaguchi, Kensei K; Tsuchihara, Katsuya K
Publication Date: 2018-06

Variant appearance in text: NRAS: K117N
PubMed Link: 29873882
Variant Present in the following documents:
  • CAS-109-2074-s001.pdf
View BVdb publication page



Testing for NRAS Mutations in Serous Borderline Ovarian Tumors and Low-Grade Serous Ovarian Carcinomas.

Disease Markers
Sadlecki, Pawel P; Grzanka, Dariusz D; Grabiec, Marek M
Publication Date: 2018

Variant appearance in text: NRAS: 351G>T; K117N
PubMed Link: 29682098
Variant Present in the following documents:
  • Main text
  • DM2018-1497879.pdf
View BVdb publication page



Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.

Cell Reports
Way, Gregory P GP; Sanchez-Vega, Francisco F; La, Konnor K; Armenia, Joshua J; Chatila, Walid K WK; Luna, Augustin A; Sander, Chris C; Cherniack, Andrew D AD; Mina, Marco M; Ciriello, Giovanni G; Schultz, Nikolaus N; , ; Sanchez, Yolanda Y; Greene, Casey S CS
Publication Date: 2018-04-03

Variant appearance in text: NRAS: Lys117Asn
PubMed Link: 29617658
Variant Present in the following documents:
  • NIHMS958974-supplement-6.xlsx, sheet 1
View BVdb publication page



Identification of the genetic and clinical characteristics of neuroblastomas using genome-wide analysis.

Oncotarget
Uryu, Kumiko K; Nishimura, Riki R; Kataoka, Keisuke K; Sato, Yusuke Y; Nakazawa, Atsuko A; Suzuki, Hiromichi H; Yoshida, Kenichi K; Seki, Masafumi M; Hiwatari, Mitsuteru M; Isobe, Tomoya T; Shiraishi, Yuichi Y; Chiba, Kenichi K; Tanaka, Hiroko H; Miyano, Satoru S; Koh, Katsuyoshi K; Hanada, Ryoji R; Oka, Akira A; Hayashi, Yasuhide Y; Ohira, Miki M; Kamijo, Takehiko T; Nagase, Hiroki H; Takimoto, Tetsuya T; Tajiri, Tatsuro T; Nakagawara, Akira A; Ogawa, Seishi S; Takita, Junko J
Publication Date: 2017-12-08

Variant appearance in text: NRAS: K117N
PubMed Link: 29296183
Variant Present in the following documents:
  • oncotarget-08-107513-s001.pdf
View BVdb publication page



Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer.

Oncotarget
Shimada, Yoshifumi Y; Kameyama, Hitoshi H; Nagahashi, Masayuki M; Ichikawa, Hiroshi H; Muneoka, Yusuke Y; Yagi, Ryoma R; Tajima, Yosuke Y; Okamura, Takuma T; Nakano, Masato M; Sakata, Jun J; Kobayashi, Takashi T; Nogami, Hitoshi H; Maruyama, Satoshi S; Takii, Yasumasa Y; Hayashida, Tetsu T; Takaishi, Hiromasa H; Kitagawa, Yuko Y; Oki, Eiji E; Konishi, Tsuyoshi T; Ishida, Fumio F; Kudo, Shin-Ei SE; Ring, Jennifer E JE; Protopopov, Alexei A; Lyle, Stephen S; Ling, Yiwei Y; Okuda, Shujiro S; Ishikawa, Takashi T; Akazawa, Kohei K; Takabe, Kazuaki K; Wakai, Toshifumi T
Publication Date: 2017-11-07

Variant appearance in text: NRAS: K117N
PubMed Link: 29212173
Variant Present in the following documents:
  • oncotarget-08-93567-s003.xlsx, sheet 1
View BVdb publication page



Clinical performance evaluation of the Idylla NRAS-BRAF mutation test on retrospectively collected formalin-fixed paraffin-embedded colorectal cancer tissue.

Journal Of Clinical Pathology
Johnston, Louise L; Power, Michael M; Sloan, Philip P; Long, Anna A; Silmon, Angela A; Chaffey, Ben B; Lisgo, Andrea Jane AJ; Little, Liam L; Vercauteren, Ellen E; Steiniche, Torben T; Meyer, Tine T; Simpson, John J
Publication Date: 2018-04

Variant appearance in text: NRAS: 351G>T; Lys117Asn
PubMed Link: 28899979
Variant Present in the following documents:
  • Main text
  • jclinpath-2017-204629.pdf
View BVdb publication page



The role of primary tumour sidedness, EGFR gene copy number and EGFR promoter methylation in RAS/BRAF wild-type colorectal cancer patients receiving irinotecan/cetuximab.

British Journal Of Cancer
Demurtas, Laura L; Puzzoni, Marco M; Giampieri, Riccardo R; Ziranu, Pina P; Pusceddu, Valeria V; Mandolesi, Alessandra A; Cremolini, Chiara C; Masi, Gianluca G; Gelsomino, Fabio F; Antoniotti, Carlotta C; Loretelli, Cristian C; Meriggi, Fausto F; Zaniboni, Alberto A; Falcone, Alfredo A; Cascinu, Stefano S; Scartozzi, Mario M
Publication Date: 2017-07-25

Variant appearance in text: N-ras: K117N
PubMed Link: 28632725
Variant Present in the following documents:
  • Main text
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: NRAS: K117N
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
  • ncomms15086.pdf
View BVdb publication page



In vivo and ex vivo cetuximab sensitivity assay using three-dimensional primary culture system to stratify KRAS mutant colorectal cancer.

Plos One
Tashiro, Takahiro T; Okuyama, Hiroaki H; Endo, Hiroko H; Kawada, Kenji K; Ashida, Yasuko Y; Ohue, Masayuki M; Sakai, Yoshiharu Y; Inoue, Masahiro M
Publication Date: 2017

Variant appearance in text: NRAS: K117N
PubMed Link: 28301591
Variant Present in the following documents:
  • Main text
View BVdb publication page



Blood-based detection of RAS mutations to guide anti-EGFR therapy in colorectal cancer patients: concordance of results from circulating tumor DNA and tissue-based RAS testing.

Molecular Oncology
Schmiegel, Wolff W; Scott, Rodney J RJ; Dooley, Susan S; Lewis, Wendy W; Meldrum, Cliff J CJ; Pockney, Peter P; Draganic, Brian B; Smith, Steve S; Hewitt, Chelsee C; Philimore, Hazel H; Lucas, Amanda A; Shi, Elva E; Namdarian, Kateh K; Chan, Timmy T; Acosta, Danilo D; Ping-Chang, Su S; Tannapfel, Andrea A; Reinacher-Schick, Anke A; Uhl, Waldemar W; Teschendorf, Christian C; Wolters, Heiner H; Stern, Josef J; Viebahn, Richard R; Friess, Helmut H; Janssen, Klaus-Peter KP; Nitsche, Ulrich U; Slotta-Huspenina, Julia J; Pohl, Michael M; Vangala, Deepak D; Baraniskin, Alexander A; Dockhorn-Dworniczak, Barbara B; Hegewisch-Becker, Susanne S; Ronga, Philippe P; Edelstein, Daniel L DL; Jones, Frederick S FS; Hahn, Stephan S; Fox, Stephen B SB
Publication Date: 2017-02

Variant appearance in text: NRAS: K117N
PubMed Link: 28106345
Variant Present in the following documents:
  • Main text
View BVdb publication page



High Intra- and Inter-Tumoral Heterogeneity of RAS Mutations in Colorectal Cancer.

International Journal Of Molecular Sciences
Jeantet, Marion M; Tougeron, David D; Tachon, Gaelle G; Cortes, Ulrich U; Archambaut, Céline C; Fromont, Gaelle G; Karayan-Tapon, Lucie L
Publication Date: 2016-12-01

Variant appearance in text: NRAS: K117N
PubMed Link: 27916952
Variant Present in the following documents:
  • Main text
  • ijms-17-02015-s001.pdf
  • ijms-17-02015.pdf
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Use of a High-Throughput Genotyping Platform (OncoMap) for RAS Mutational Analysis to Predict Cetuximab Efficacy in Patients with Metastatic Colorectal Cancer.

Cancer Research And Treatment
Kim, Dalyong D; Hong, Yong Sang YS; Kim, Jeong Eun JE; Kim, Kyu-Pyo KP; Lee, Jae-Lyun JL; Chun, Sung-Min SM; Kim, Jihun J; Jang, Se Jin SJ; Kim, Tae Won TW
Publication Date: 2017-01

Variant appearance in text: NRAS: K117N
PubMed Link: 27121720
Variant Present in the following documents:
  • crt-2016-069.pdf
View BVdb publication page



Panel sequencing for clinically oriented variant screening and copy number detection in 142 untreated multiple myeloma patients.

Blood Cancer Journal
Kortuem, K M KM; Braggio, E E; Bruins, L L; Barrio, S S; Shi, C S CS; Zhu, Y X YX; Tibes, R R; Viswanatha, D D; Votruba, P P; Ahmann, G G; Fonseca, R R; Jedlowski, P P; Schlam, I I; Kumar, S S; Bergsagel, P L PL; Stewart, A K AK
Publication Date: 2016-02-26

Variant appearance in text: NRAS: Lys117Asn
PubMed Link: 26918361
Variant Present in the following documents:
  • bcj20161x1.pdf
View BVdb publication page



Detection of KRAS, NRAS and BRAF by mass spectrometry - a sensitive, reliable, fast and cost-effective technique.

Diagnostic Pathology
Kriegsmann, Mark M; Arens, Norbert N; Endris, Volker V; Weichert, Wilko W; Kriegsmann, Jörg J
Publication Date: 2015-07-30

Variant appearance in text: NRAS: K117N
PubMed Link: 26220423
Variant Present in the following documents:
  • Main text
View BVdb publication page



Clinical Validation of a Multiplex Kit for RAS Mutations in Colorectal Cancer: Results of the RASKET (RAS KEy Testing) Prospective, Multicenter Study.

Ebiomedicine
Yoshino, Takayuki T; Muro, Kei K; Yamaguchi, Kensei K; Nishina, Tomohiro T; Denda, Tadamichi T; Kudo, Toshihiro T; Okamoto, Wataru W; Taniguchi, Hiroya H; Akagi, Kiwamu K; Kajiwara, Takeshi T; Hironaka, Shuichi S; Satoh, Taroh T
Publication Date: 2015-04

Variant appearance in text: NRAS: K117N
PubMed Link: 26137573
Variant Present in the following documents:
  • Main text
View BVdb publication page



Replicative DNA polymerase mutations in cancer.

Current Opinion In Genetics & Development
Heitzer, Ellen E; Tomlinson, Ian I
Publication Date: 2014-02

Variant appearance in text: NRAS: K117N
PubMed Link: 24583393
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Mitochondrial oxidative stress is the Achille's heel of melanoma cells resistant to Braf-mutant inhibitor.

Oncotarget
Corazao-Rozas, Paola P; Guerreschi, Pierre P; Jendoubi, Manel M; André, Fanny F; Jonneaux, Aurélie A; Scalbert, Camille C; Garçon, Guillaume G; Malet-Martino, Myriam M; Balayssac, Stéphane S; Rocchi, Stephane S; Savina, Ariel A; Formstecher, Pierre P; Mortier, Laurent L; Kluza, Jérome J; Marchetti, Philippe P
Publication Date: 2013-11

Variant appearance in text: NRAS: K117N
PubMed Link: 24161908
Variant Present in the following documents:
  • Main text
  • oncotarget-04-1986.pdf
View BVdb publication page