NRAS c.207C>G ;(p.D69E)

Variant ID: 1-115256504-G-C

NM_002524.4(NRAS):c.207C>G;(p.D69E)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.

Cell Reports
Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM
Publication Date: 2020-06-23

Variant appearance in text: NRAS: D69E
PubMed Link: 32579932
Variant Present in the following documents:
  • mmc5.xlsx, sheet 3
View BVdb publication page



Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities.

Nature Cell Biology
Coppé, Jean-Philippe JP; Mori, Miki M; Pan, Bo B; Yau, Christina C; Wolf, Denise M DM; Ruiz-Saenz, Ana A; Brunen, Diede D; Prahallad, Anirudh A; Cornelissen-Steijger, Paulien P; Kemper, Kristel K; Posch, Christian C; Wang, Changjun C; Dreyer, Courtney A CA; Krijgsman, Oscar O; Lee, Pei Rong Evelyn PRE; Chen, Zhongzhong Z; Peeper, Daniel S DS; Moasser, Mark M MM; Bernards, René R; van 't Veer, Laura J LJ
Publication Date: 2019-06

Variant appearance in text: NRAS: D69E
PubMed Link: 31160710
Variant Present in the following documents:
  • Main text
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: NRAS: D69E
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 1
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page