NRAS c.190T>A ;(p.Y64N)

Variant ID: 1-115256521-A-T

NM_002524.4(NRAS):c.190T>A;(p.Y64N)

This variant was identified in 15 publications

View GRCh38 version.




Publications:


Pathophysiologic and clinical implications of molecular profiles resultant from deletion 5q.

Ebiomedicine
Adema, Vera V; Palomo, Laura L; Walter, Wencke W; Mallo, Mar M; Hutter, Stephan S; La Framboise, Thomas T; Arenillas, Leonor L; Meggendorfer, Manja M; Radivoyevitch, Tomas T; Xicoy, Blanca B; Pellagatti, Andrea A; Haferlach, Claudia C; Boultwood, Jacqueline J; Kern, Wolfgang W; Visconte, Valeria V; Sekeres, Mikkael M; Barnard, John J; Haferlach, Torsten T; Solé, Francesc F; Maciejewski, Jaroslaw P JP
Publication Date: 2022-06

Variant appearance in text: NRAS: 190T>A; Tyr64Asn
PubMed Link: 35617825
Variant Present in the following documents:
  • mmc3.xlsx, sheet 1
View BVdb publication page



Divergent clonal evolution of blastic plasmacytoid dendritic cell neoplasm and chronic myelomonocytic leukemia from a shared TET2-mutated origin.

Leukemia
Batta, Kiran K; Bossenbroek, Hasse M HM; Pemmaraju, Naveen N; Wilks, Deepti P DP; Chasty, Richard R; Dennis, Mike M; Milne, Paul P; Collin, Matthew M; Beird, Hannah C HC; Taylor, Justin J; Patnaik, Mrinal M MM; Cargo, Catherine A CA; Somervaille, Tim C P TCP; Wiseman, Daniel H DH
Publication Date: 2021-11

Variant appearance in text: NRAS: Tyr64Asn
PubMed Link: 33833384
Variant Present in the following documents:
  • Main text
  • 41375_2021_1228_MOESM2_ESM.xlsx, sheet 1
  • 41375_2021_Article_1228.pdf
View BVdb publication page



Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: NRAS: 190T>A; Y64N
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Clinical utility of target capture-based panel sequencing in hematological malignancies: A multicenter feasibility study.

Cancer Science
Yasuda, Takahiko T; Sanada, Masashi M; Nishijima, Dai D; Kanamori, Takashi T; Iijima, Yuka Y; Hattori, Hiroyoshi H; Saito, Akiko A; Miyoshi, Hiroaki H; Ishikawa, Yuichi Y; Asou, Norio N; Usuki, Kensuke K; Hirabayashi, Shinsuke S; Kato, Motohiro M; Ri, Masaki M; Handa, Hiroshi H; Ishida, Tadao T; Shibayama, Hirohiko H; Abe, Masahiro M; Iriyama, Chisako C; Karube, Kennosuke K; Nishikori, Momoko M; Ohshima, Koichi K; Kataoka, Keisuke K; Yoshida, Kenichi K; Shiraishi, Yuichi Y; Goto, Hiroaki H; Adachi, Souichi S; Kobayashi, Ryoji R; Kiyoi, Hitoshi H; Miyazaki, Yasushi Y; Ogawa, Seishi S; Kurahashi, Hiroki H; Yokoyama, Hisayuki H; Manabe, Atsushi A; Iida, Shinsuke S; Tomita, Akihiro A; Horibe, Keizo K
Publication Date: 2020-09

Variant appearance in text: NRAS: Y64N
PubMed Link: 32619037
Variant Present in the following documents:
  • CAS-111-3367-s004.xlsx, sheet 4
View BVdb publication page



Single-cell analysis based dissection of clonality in myelofibrosis.

Nature Communications
Mylonas, Elena E; Yoshida, Kenichi K; Frick, Mareike M; Hoyer, Kaja K; Christen, Friederike F; Kaeda, Jaspal J; Obenaus, Matthias M; Noerenberg, Daniel D; Hennch, Cornelius C; Chan, Willy W; Ochi, Yotaro Y; Shiraishi, Yuichi Y; Shiozawa, Yusuke Y; Zenz, Thorsten T; Oakes, Christopher C CC; Sawitzki, Birgit B; Schwarz, Michaela M; Bullinger, Lars L; le Coutre, Philipp P; Rose-Zerilli, Matthew J J MJJ; Ogawa, Seishi S; Damm, Frederik F
Publication Date: 2020-01-07

Variant appearance in text: NRAS: Y64N
PubMed Link: 31911629
Variant Present in the following documents:
  • 41467_2019_13892_MOESM4_ESM.xlsx, sheet 3
View BVdb publication page



appreci8: a pipeline for precise variant calling integrating 8 tools.

Bioinformatics (Oxford, England)
Sandmann, Sarah S; Karimi, Mohsen M; de Graaf, Aniek O AO; Rohde, Christian C; Göllner, Stefanie S; Varghese, Julian J; Ernsting, Jan J; Walldin, Gunilla G; van der Reijden, Bert A BA; Müller-Tidow, Carsten C; Malcovati, Luca L; Hellström-Lindberg, Eva E; Jansen, Joop H JH; Dugas, Martin M
Publication Date: 2018-12-15

Variant appearance in text: NRAS: 190T>A; Tyr64Asn
PubMed Link: 29945233
Variant Present in the following documents:
  • bty518_supplementary_data_s3.xlsx, sheet 9
View BVdb publication page



A novel type of NPM1 mutation characterized by multiple internal tandem repeats in a case of cytogenetically normal acute myeloid leukemia.

Haematologica
Duployez, Nicolas N; Chebrek, Lydia L; Helevaut, Nathalie N; Fournier, Elise E; Bemba, Maxime M; Caillault, Aurélie A; Geffroy, Sandrine S; Preudhomme, Claude C
Publication Date: 2018-12

Variant appearance in text: NRAS: Y64N
PubMed Link: 29903763
Variant Present in the following documents:
  • Main text
View BVdb publication page



Distinct age-associated molecular profiles in acute myeloid leukemia defined by comprehensive clinical genomic profiling.

Oncotarget
Tarlock, Katherine K; Zhong, Shan S; He, Yuting Y; Ries, Rhonda R; Severson, Eric E; Bailey, Mark M; Morley, Samantha S; Balasubramanian, Sohail S; Erlich, Rachel R; Lipson, Doron D; Otto, Geoff A GA; Vergillo, Jo-Anne JA; Kolb, E Anders EA; Ross, Jeffrey S JS; Mughal, Tariq T; Stephens, Philip J PJ; Miller, Vincent V; Meshinchi, Soheil S; He, Jie J
Publication Date: 2018-05-29

Variant appearance in text: NRAS: 190T>A; Y64N
PubMed Link: 29899868
Variant Present in the following documents:
  • oncotarget-09-26417-s005.xlsx, sheet 1
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: NRAS: Y64N
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 1
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Ongoing clonal evolution in chronic myelomonocytic leukemia on hypomethylating agents: a computational perspective.

Leukemia
Than, Hein H; Qiao, Yi Y; Huang, Xiaomeng X; Yan, Dongqing D; Khorashad, Jamshid S JS; Pomicter, Anthony D AD; Kovacsovics, Tibor J TJ; Marth, Gabor T GT; O'Hare, Thomas T; Deininger, Michael W MW
Publication Date: 2018-09

Variant appearance in text: NRAS: Y64N
PubMed Link: 29588547
Variant Present in the following documents:
  • NIHMS933711-supplement-1.pdf
View BVdb publication page



Detecting protein variants by mass spectrometry: a comprehensive study in cancer cell-lines.

Genome Medicine
Alfaro, Javier A JA; Ignatchenko, Alexandr A; Ignatchenko, Vladimir V; Sinha, Ankit A; Boutros, Paul C PC; Kislinger, Thomas T
Publication Date: 2017-07-18

Variant appearance in text: NRAS: Y64N
PubMed Link: 28716134
Variant Present in the following documents:
  • 13073_2017_454_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Identification of a genetically defined ultra-high-risk group in relapsed pediatric T-lymphoblastic leukemia.

Blood Cancer Journal
Richter-Pechańska, P P; Kunz, J B JB; Hof, J J; Zimmermann, M M; Rausch, T T; Bandapalli, O R OR; Orlova, E E; Scapinello, G G; Sagi, J C JC; Stanulla, M M; Schrappe, M M; Cario, G G; Kirschner-Schwabe, R R; Eckert, C C; Benes, V V; Korbel, J O JO; Muckenthaler, M U MU; Kulozik, A E AE
Publication Date: 2017-02-03

Variant appearance in text: NRAS: Y64N
PubMed Link: 28157215
Variant Present in the following documents:
  • bcj20173x11.xlsx, sheet 1
View BVdb publication page



Peripheral blood cell-free DNA is an alternative tumor DNA source reflecting disease status in myelodysplastic syndromes.

Cancer Science
Suzuki, Yasuhiro Y; Tomita, Akihiro A; Nakamura, Fumika F; Iriyama, Chisako C; Shirahata-Adachi, Mizuho M; Shimada, Kazuyuki K; Akashi, Akimi A; Ishikawa, Yuichi Y; Kaneda, Norio N; Kiyoi, Hitoshi H
Publication Date: 2016-09

Variant appearance in text: NRAS: Y64N
PubMed Link: 27323954
Variant Present in the following documents:
  • CAS-107-1329.pdf
View BVdb publication page



The role of the RAS pathway in iAMP21-ALL.

Leukemia
Ryan, S L SL; Matheson, E E; Grossmann, V V; Sinclair, P P; Bashton, M M; Schwab, C C; Towers, W W; Partington, M M; Elliott, A A; Minto, L L; Richardson, S S; Rahman, T T; Keavney, B B; Skinner, R R; Bown, N N; Haferlach, T T; Vandenberghe, P P; Haferlach, C C; Santibanez-Koref, M M; Moorman, A V AV; Kohlmann, A A; Irving, J A E JA; Harrison, C J CJ
Publication Date: 2016-09

Variant appearance in text: NRAS: Y64N
PubMed Link: 27168466
Variant Present in the following documents:
  • leu201680x2.xlsx, sheet 5
View BVdb publication page



Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research
Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C
Publication Date: 2011-09-01

Variant appearance in text: NRAS: Y64N
PubMed Link: 21727090
Variant Present in the following documents:
  • supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1
View BVdb publication page