Publications:

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Comparative efficacy and safety of multitarget angiogenesis inhibitor combined with immune checkpoint inhibitor and nivolumab monotherapy as second-line or beyond for advanced lung adenocarcinoma in driver-negative patients: a retrospective comparative cohort study.

Translational Lung Cancer Research

Yu, Lian L; Xu, Jianlin J; Qiao, Rong R; Zhong, Hua H; Brueckl, Wolfgang M WM; Zhong, Runbo R

Publication Date: 2023-05-31

Variant appearance in text: NRAS: Q61H

PubMed Link: 37323173

Variant Present in the following documents:

• tlcr-12-05-1108-supplementary.pdf

View BVdb publication page

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Analysis of Circulating Tumor DNA in Synchronous Metastatic Colorectal Cancer at Diagnosis Predicts Overall Patient Survival.

International Journal Of Molecular Sciences

Sayagués, José María JM; Montero, Juan Carlos JC; Jiménez-Pérez, Andrea A; Del Carmen, Sofía S; Rodríguez, Marta M; Vidal Tocino, Rosario R; Montero, Enrique E; Sanz, Julia J; Abad, Mar M

Publication Date: 2023-05-08

Variant appearance in text: NRAS: Q61H

PubMed Link: 37176143

Variant Present in the following documents:

• ijms-24-08438.pdf

View BVdb publication page

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Molecular profiling of colorectal cancer in a genetically admixed Hispanic population.

Cancer Medicine

Montes-Rodríguez, Ingrid M IM; Centeno-Girona, Hilmaris H; Rivera-Lynch, Camila C; Rivera, Noridza N; Cruz-Correa, Marcia M

Publication Date: 2023-04-11

Variant appearance in text: NRAS: Q61H

PubMed Link: 37039257

Variant Present in the following documents:

• CAM4-12-11686-s002.xlsx, sheet 1

View BVdb publication page

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Anti-CLL1-based CAR T-cells with 4-1-BB or CD28/CD27 stimulatory domains in treating childhood refractory/relapsed acute myeloid leukemia.

Cancer Medicine

Pei, Kunlin K; Xu, Haoyu H; Wang, Pengfei P; Gan, Wening W; Hu, Zhengbin Z; Su, Xiaoling X; Zhang, Hui H; He, Yingyi Y

Publication Date: 2023-04-09

Variant appearance in text: NRAS: Q61H

PubMed Link: 37031462

Variant Present in the following documents:

• Main text

View BVdb publication page

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Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: NRAS: Q61H

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2

View BVdb publication page

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Deep genomic characterization highlights complexities and prognostic markers of pediatric acute myeloid leukemia.

Communications Biology

Cheng, Chi-Keung CK; Yung, Yuk-Lin YL; Chan, Hoi-Yun HY; Leung, Kam-Tong KT; Chan, Kathy Y Y KYY; Leung, Alex W K AWK; Cheng, Frankie W T FWT; Li, Chi-Kong CK; Wan, Thomas S K TSK; Luo, Xi X; Pitts, Herbert-Augustus HA; Cheung, Joyce S JS; Chan, Natalie P H NPH; Ng, Margaret H L MHL

Publication Date: 2023-03-31

Variant appearance in text: NRAS: 183A>T; Q61H; rs121913255

PubMed Link: 37002311

Variant Present in the following documents:

• 42003_2023_4732_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Late-stage metastatic melanoma emerges through a diversity of evolutionary pathways.

Cancer Discovery

Spain, Lavinia L; Coulton, Alexander A; Lobon, Irene I; Rowan, Andrew A; Schnidrig, Desiree D; Shepherd, Scott T C STC; Shum, Benjamin B; Byrne, Fiona F; Goicoechea, Maria M; Piperni, Elisa E; Au, Lewis L; Edmonds, Kim K; Carlyle, Eleanor E; Hunter, Nikki N; Renn, Alexandra A; Messiou, Christina C; Hughes, Peta P; Nobbs, Jaime J; Foijer, Floris F; van den Bos, Hilda H; Wardenaar, Rene R; Spierings, Diana C J DCJ; Spencer, Charlotte C; Schmitt, Andreas M AM; Tippu, Zayd Z; Lingard, Karla K; Grostate, Lauren L; Peat, Kema K; Kelly, Kayleigh K; Sarker, Sarah S; Vaughan, Sarah S; Mangwende, Mary M; Terry, Lauren L; Kelly, Denise D; Biano, Jennifer J; Murra, Aida A; Korteweg, Justine J; Lewis, Charlotte C; OFlaherty, Molly M; Cattin, Anne-Laure AL; Emmerich, Max M; Gerard, Camille L CL; Pallikonda, Husayn Ahmed HA; Lynch, Joanna J; Mason, Robert R; Rogiers, Aljosja A; Xu, Hang H; Huebner, Ariana A; McGranahan, Nicholas N; Al Bakir, Maise M; Murai, Jun J; Naceur-Lombardelli, Cristina C; Borg, Elaine E; Mitchison, Miriam M; Moore, David A DA; Falzon, Mary M; Proctor, Ian I; Stamp, Gordon W H GWH; Nye, Emma L EL; Young, Kate K; Furness, Andrew J S AJS; Pickering, Lisa L; Stewart, Ruby R; Mahadeva, Ula U; Green, Anna A; Larkin, James J; Litchfield, Kevin K; Swanton, Charles C; Jamal-Hanjani, Mariam M; Turajlic, Samra S

Publication Date: 2023-03-28

Variant appearance in text: NRAS: Q61H

PubMed Link: 36977461

Variant Present in the following documents:

• Main text
• 1364.pdf

View BVdb publication page

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KRAS, NRAS, BRAF, and PIK3CA mutation rates, clinicopathological association, and their prognostic value in Iranian colorectal cancer patients.

Journal Of Clinical Laboratory Analysis

Mirzapoor Abbasabadi, Zohreh Z; Hamedi Asl, Dariush D; Rahmani, Babak B; Shahbadori, Rozhin R; Karami, Sara S; Peymani, Amir A; Taghizadeh, Sara S; Samiee Rad, Fatemeh F

Publication Date: 2023-03-17

Variant appearance in text: NRAS: Q61H

PubMed Link: 36930789

Variant Present in the following documents:

• JCLA-37-e24868.pdf

View BVdb publication page

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Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications

Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G

Publication Date: 2023-03-11

Variant appearance in text: NRAS: Q61H

PubMed Link: 36906579

Variant Present in the following documents:

• 41467_2023_36922_MOESM4_ESM.xls, sheet 2

View BVdb publication page

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Liquid biopsy by analysis of circulating myeloma cells and cell-free nucleic acids: a novel noninvasive approach of disease evaluation in multiple myeloma.

Biomarker Research

Li, Shuchan S; Zhang, Enfan E; Cai, Zhen Z

Publication Date: 2023-03-08

Variant appearance in text: NRAS: Q61H

PubMed Link: 36890597

Variant Present in the following documents:

• Main text
• 40364_2023_Article_469.pdf

View BVdb publication page

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KRAS, NRAS, BRAF signatures, and MMR status in colorectal cancer patients in North China.

Medicine

Lian, Shen-Yi SY; Tan, Lu-Xin LX; Liu, Xin-Zhi XZ; Yang, Lu-Jing LJ; Li, Ning-Ning NN; Feng, Qing Q; Wang, Ping P; Wang, Yue Y; Qiao, Dong-Bo DB; Zhou, Li-Xin LX; Sun, Ting-Ting TT; Wang, Lin L; Wu, Ai-Wen AW; Li, Zhong-Wu ZW

Publication Date: 2023-03-03

Variant appearance in text: NRAS: Q61H

PubMed Link: 36862900

Variant Present in the following documents:

• Main text
• medi-102-e33115.pdf

View BVdb publication page

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High-risk multiple myeloma predicted by circulating plasma cells and its genetic characteristics.

Frontiers In Oncology

Xia, Yuan Y; Shen, Na N; Zhang, Run R; Wu, Yujie Y; Shi, Qinglin Q; Li, Jianyong J; Chen, Lijuan L; Xu, Min M; Jin, Yuanyuan Y

Publication Date: 2023

Variant appearance in text: rs121913255

PubMed Link: 36845679

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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BdLT-Seq as a barcode decay-based method to unravel lineage-linked transcriptome plasticity.

Nature Communications

Shlyakhtina, Yelyzaveta Y; Bloechl, Bianca B; Portal, Maximiliano M MM

Publication Date: 2023-02-25

Variant appearance in text: NRAS: Q61H

PubMed Link: 36841849

Variant Present in the following documents:

• 41467_2023_36744_MOESM1_ESM.pdf

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: NRAS: 183A>T; Gln61His

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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CAR-T cell therapy followed by allogenic hematopoietic stem cell transplantation yielded comparable outcome between Ph like ALL and other high-risk ALL.

Biomarker Research

Dai, Hai-Ping HP; Kong, Dan-Qing DQ; Shen, Hong-Jie HJ; Cui, Wei W; Wang, Qian Q; Li, Zheng Z; Yin, Jia J; Kang, Li-Qing LQ; Yu, Lei L; Wu, De-Pei DP; Tang, Xiao-Wen XW

Publication Date: 2023-02-15

Variant appearance in text: NRAS: Q61H

PubMed Link: 36793095

Variant Present in the following documents:

• Main text
• 40364_2023_Article_451.pdf

View BVdb publication page

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Multilevel proteomic analyses reveal molecular diversity between diffuse-type and intestinal-type gastric cancer.

Nature Communications

Shi, Wenhao W; Wang, Yushen Y; Xu, Chen C; Li, Yan Y; Ge, Sai S; Bai, Bin B; Zhang, Kecheng K; Wang, Yunzhi Y; Zheng, Nairen N; Wang, Juan J; Wang, Shiqi S; Ji, Gang G; Li, Jipeng J; Nie, Yongzhan Y; Liang, Wenquan W; Wu, Xiaosong X; Cui, Jianxin J; Wang, Yi Y; Chen, Lin L; Zhao, Qingchuan Q; Shen, Lin L; He, Fuchu F; Qin, Jun J; Ding, Chen C

Publication Date: 2023-02-14

Variant appearance in text: NRAS: 183A>T; Q61H

PubMed Link: 36788224

Variant Present in the following documents:

• 41467_2023_35797_MOESM4_ESM.xlsx, sheet 2

View BVdb publication page

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Circulating tumour DNA analysis predicts relapse and improves risk stratification in primary refractory multiple myeloma.

Blood Cancer Journal

Mithraprabhu, Sridurga S; Reynolds, John J; Turner, Rose R; Quach, Hang H; Horvath, Noemi N; Kerridge, Ian I; Kalff, Anna A; Bergin, Krystal K; Hocking, Jay J; Yuen, Flora F; Khong, Tiffany T; Durie, Brian M BM; Spencer, Andrew A

Publication Date: 2023-02-13

Variant appearance in text: NRAS: 183A>T; Q61H

PubMed Link: 36781844

Variant Present in the following documents:

• 41408_2023_796_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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A New Indicator to Differentiate Thyroid Follicular Inclusions in Cervical Lymph Nodes from Patients with Thyroid Cancer.

International Journal Of Molecular Sciences

Otsubo, Chieko C; Mussazhanova, Zhanna Z; Kurohama, Hirokazu H; Shalgimbayeva, Gulzira G; Ueki, Nozomi N; Matsuoka, Yuki Y; Madiyeva, Madina M; Sato, Shinya S; Yamashita, Hiroyuki H; Nakashima, Masahiro M

Publication Date: 2022-12-28

Variant appearance in text: NRAS: Q61H

PubMed Link: 36613940

Variant Present in the following documents:

• Main text
• ijms-24-00490.pdf

View BVdb publication page

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Molecular underpinnings of exceptional response in primary malignant melanoma of the esophagus to anti-PD-1 monotherapy.

Journal For Immunotherapy Of Cancer

Dai, Jie J; Bai, Xue X; Gao, Xuan X; Tang, Lirui L; Chen, Yu Y; Sun, Linzi L; Wei, Xiaoting X; Li, Caili C; Qi, Zhonghui Z; Kong, Yan Y; Cui, Chuanliang C; Chi, Zhihong Z; Sheng, Xinan X; Xu, Zelong Z; Lian, Bin B; Li, Siming S; Yan, Xieqiao X; Tang, Bixia B; Zhou, Li L; Wang, Xuan X; Xia, Xuefeng X; Guo, Jun J; Mao, Lili L; Si, Lu L

Publication Date: 2023-01

Variant appearance in text: NRAS: 183A>T; Gln61His

PubMed Link: 36593066

Variant Present in the following documents:

• jitc-2022-005937supp007.xls, sheet 1

View BVdb publication page

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Evolution of RAS Mutations in Cell-Free DNA of Patients with Tissue RAS Wild-Type Metastatic Colorectal Cancer Receiving First-Line Treatment: The PERSEIDA Study.

Cancers

Valladares-Ayerbes, Manuel M; Garcia-Alfonso, Pilar P; Muñoz Luengo, Jorge J; Pimentel Caceres, Paola Patricia PP; Castillo Trujillo, Oscar Alfredo OA; Vidal-Tocino, Rosario R; Llanos, Marta M; Llorente Ayala, Beatriz B; Limon Miron, Maria Luisa ML; Salud, Antonieta A; Cirera Nogueras, Luis L; Garcia-Carbonero, Rocio R; Safont, Maria Jose MJ; Falco Ferrer, Esther E; Aparicio, Jorge J; Vicente Conesa, Maria Angeles MA; Guillén-Ponce, Carmen C; Garcia-Teijido, Paula P; Medina Magan, Maria Begoña MB; Busquier, Isabel I; Salgado, Mercedes M; Lloansí Vila, Ariadna A; ,

Publication Date: 2022-12-09

Variant appearance in text: NRAS: 183A>T

PubMed Link: 36551560

Variant Present in the following documents:

• Main text
• cancers-14-06075.pdf

View BVdb publication page

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Targeting KRASG12C in colorectal cancer: the beginning of a new era.

Esmo Open

Ciardiello, D D; Maiorano, B A BA; Martinelli, E E

Publication Date: 2022-12-20

Variant appearance in text: NRAS: Q61H

PubMed Link: 36549128

Variant Present in the following documents:

• main.pdf

View BVdb publication page

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Single-cell analysis reveals the chemotherapy-induced cellular reprogramming and novel therapeutic targets in relapsed/refractory acute myeloid leukemia.

Leukemia

Li, Kening K; Du, Yuxin Y; Cai, Yun Y; Liu, Wenjie W; Lv, Yan Y; Huang, Bin B; Zhang, Lishen L; Wang, Zhi Z; Liu, Ping P; Sun, Qian Q; Li, Ning N; Zhu, Mengyan M; Bosco, Bakwatanisa B; Li, Liangyu L; Wu, Wei W; Wu, Lingxiang L; Li, Jianyong J; Wang, Qianghu Q; Hong, Ming M; Qian, Sixuan S

Publication Date: 2022-12-21

Variant appearance in text: NRAS: 183A>T; Q61H

PubMed Link: 36543880

Variant Present in the following documents:

• 41375_2022_1789_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Role of RAS signaling in ovarian cancer.

F1000Research

Therachiyil, Lubna L; Anand, Anjana A; Azmi, Abdullah A; Bhat, Ajaz A; Korashy, Hesham M HM; Uddin, Shahab S

Publication Date: 2022

Variant appearance in text: NRAS: Q61H

PubMed Link: 36451660

Variant Present in the following documents:

• Main text
• f1000research-11-138739.pdf

View BVdb publication page

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Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Cheng, Wen-Yan WY; Li, Jian-Feng JF; Zhu, Yong-Mei YM; Lin, Xiang-Jie XJ; Wen, Li-Jun LJ; Zhang, Fan F; Zhang, Yu-Liang YL; Zhao, Ming M; Fang, Hai H; Wang, Sheng-Yue SY; Lin, Xiao-Jing XJ; Qiao, Niu N; Yin, Wei W; Zhang, Jia-Nan JN; Dai, Yu-Ting YT; Jiang, Lu L; Sun, Xiao-Jian XJ; Xu, Yi Y; Zhang, Tong-Tong TT; Chen, Su-Ning SN; Zhu, Hong-Hu HH; Chen, Zhu Z; Jin, Jie J; Wu, De-Pei DP; Shen, Yang Y; Chen, Sai-Juan SJ

Publication Date: 2022-12-06

Variant appearance in text: NRAS: Q61H

PubMed Link: 36442087

Variant Present in the following documents:

• pnas.2211429119.sd02.xlsx, sheet 1
• pnas.2211429119.sapp.pdf

View BVdb publication page

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A sex-informed approach to improve the personalised decision making process in myelodysplastic syndromes: a multicentre, observational cohort study.

The Lancet. Haematology

,

Publication Date: 2022-11-24

Variant appearance in text: NRAS: 183A>T; Q61H

PubMed Link: 36436542

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

View BVdb publication page

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Calibration of computational tools for missense variant pathogenicity classification and ClinGen recommendations for PP3/BP4 criteria.

American Journal Of Human Genetics

Pejaver, Vikas V; Byrne, Alicia B AB; Feng, Bing-Jian BJ; Pagel, Kymberleigh A KA; Mooney, Sean D SD; Karchin, Rachel R; O'Donnell-Luria, Anne A; Harrison, Steven M SM; Tavtigian, Sean V SV; Greenblatt, Marc S MS; Biesecker, Leslie G LG; Radivojac, Predrag P; Brenner, Steven E SE; ,

Publication Date: 2022-12-01

Variant appearance in text: N/A

PubMed Link: 36413997

Variant Present in the following documents:

View BVdb publication page

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: NRAS: Q61H

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Genomic landscape of the immunogenicity regulation in skin melanomas with diverse tumor mutation burden.

Frontiers In Immunology

Georgoulias, George G; Zaravinos, Apostolos A

Publication Date: 2022

Variant appearance in text: NRAS: Q61H

PubMed Link: 36389735

Variant Present in the following documents:

• Table_7.xlsx, sheet 9

View BVdb publication page

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Somatic mutations of activating signalling, transcription factor, and tumour suppressor are a precondition for leukaemia transformation in myelodysplastic syndromes.

Journal Of Cellular And Molecular Medicine

Xu, Feng F; Wu, Lin-Yun LY; Guo, Juan J; He, Qi Q; Zhang, Zheng Z; Li, Xiao X

Publication Date: 2022-12

Variant appearance in text: NRAS: Q61H

PubMed Link: 36380727

Variant Present in the following documents:

• Main text
• JCMM-26-5901.pdf

View BVdb publication page

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Prevalence and patterns of mutations in RAS/RAF/MEK/ERK/MAPK signaling pathway in colorectal cancer in North Africa.

Bmc Cancer

Jafari, Meryem M; Laraqui, Abdelilah A; Baba, Walid W; Benmokhtar, Soukaina S; Zaitouni, Sara El SE; Ali, Abdelmounaim Ait AA; Bounaim, Ahmed A; Moujahid, Mountassir M; Tanz, Rachid R; Mahfoud, Tarik T; Sbitti, Yassir Y; Annaz, Hicham El HE; Abi, Rachid R; Tagajdid, Mohamed Rida MR; Kochri, Safae El SE; Lahlou, Idriss Amine IA; Hsaini, Houda El HE; Belayachi, Lamiae L; Benjouad, Abdelaziz A; Ichou, Mohammed M; En-Nya, Amina A; Ennibi, Khalid K

Publication Date: 2022-11-07

Variant appearance in text: NRAS: 183A>T

PubMed Link: 36344948

Variant Present in the following documents:

• 12885_2022_Article_10235.pdf

View BVdb publication page

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The kinetics of blast clearance are associated with copy number alterations in childhood B-cell acute lymphoblastic leukemia.

Neoplasia (New York, N.Y.)

Urbańska, Zuzanna Z; Lejman, Monika M; Taha, Joanna J; Madzio, Joanna J; Ostrowska, Kinga K; Miarka-Walczyk, Karolina K; Wypyszczak, Kamila K; Styka, Borys B; Jakubowska, Justyna J; Sędek, Łukasz Ł; Szczepański, Tomasz T; Stańczak, Marcin M; Fendler, Wojciech W; Młynarski, Wojciech W; Pastorczak, Agata A

Publication Date: 2022-10-23

Variant appearance in text: NRAS: Gln61His

PubMed Link: 36288679

Variant Present in the following documents:

• mmc1.pdf

View BVdb publication page

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GATOR2-dependent mTORC1 activity is a therapeutic vulnerability in FOXO1 fusion-positive rhabdomyosarcoma.

Jci Insight

Morales, Jacqueline J; Allegakoen, David V DV; Garcia, José A JA; Kwong, Kristen K; Sahu, Pushpendra K PK; Fajardo, Drew A DA; Pan, Yue Y; Horlbeck, Max A MA; Weissman, Jonathan S JS; Gustafson, W Clay WC; Bivona, Trever G TG; Sabnis, Amit J AJ

Publication Date: 2022-12-08

Variant appearance in text: NRAS: Q61H

PubMed Link: 36282590

Variant Present in the following documents:

• jciinsight-7-162207.pdf

View BVdb publication page

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Whole-genome analysis identifies novel drivers and high-risk double-hit events in relapsed/refractory myeloma.

Blood

Ansari-Pour, Naser N; Samur, Mehmet K MK; Flynt, Erin E; Gooding, Sarah S; Towfic, Fadi F; Stong, Nicholas N; Ortiz Estevez, Maria M; Mavrommatis, Konstantinos K; Walker, Brian A BA; Morgan, Gareth J GJ; Munshi, Nikhil C NC; Avet Loiseau, Herve H; Thakurta, Anjan A

Publication Date: 2022-10-12

Variant appearance in text: NRAS: Q61H

PubMed Link: 36223594

Variant Present in the following documents:

• BLOOD_BLD-2022-017010-mmc2.xlsx, sheet 1

View BVdb publication page

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The mutational landscape of cancer's vulnerability to ionizing radiation.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Gopal, Priyanka P; Yard, Brian D BD; Petty, Aaron A; Lal, Jessica C JC; Bera, Titas K TK; Hoang, Trung Q TQ; Buhimschi, Alexandru B AB; Abazeed, Mohamed E ME

Publication Date: 2022-10-12

Variant appearance in text: NRAS: Q61H

PubMed Link: 36222846

Variant Present in the following documents:

• ccr-22-1914_supplementary_data_2_suppds2.xlsx, sheet 1

View BVdb publication page

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Mutually exclusive genetic interactions and gene essentiality shape the genomic landscape of primary melanoma.

The Journal Of Pathology

Birkeälv, Sofia S; Harland, Mark M; Matsuyama, Larissa Satiko Alcantara Sekimoto LSAS; Rashid, Mamun M; Mehta, Ishan I; Laye, Jonathan P JP; Haase, Kerstin K; Mell, Tracey T; Iyer, Vivek V; Robles-Espinoza, Carla Daniela CD; McDermott, Ultan U; van Loo, Peter P; Kuijjer, Marieke L ML; Possik, Patricia A PA; Maria Engler, Silvya Stuchi SS; Bishop, D Timothy DT; Newton-Bishop, Julia J; Adams, David J DJ

Publication Date: 2022-10-11

Variant appearance in text: NRAS: 183A>T; Q61H

PubMed Link: 36219477

Variant Present in the following documents:

• PATH-259-56-s006.xlsx, sheet 2
• PATH-259-56-s004.xlsx, sheet 2

View BVdb publication page

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A comprehensive next generation sequencing tissue assay for Asian-prevalent cancers-Analytical validation and performance evaluation with clinical samples.

Frontiers In Molecular Biosciences

Ng, Cedric Chuan-Young CC; Lim, Sandy S; Lim, Abner Herbert AH; Md Nasir, Nur Diyana ND; Zhang, Jingxian J; Rajasegaran, Vikneswari V; Lee, Jing Yi JY; Kok, Jessica Sook Ting JST; Thike, Aye Aye AA; Lim, Johnathan Xiande JX; Weng, Ruifen R; Yee, Sidney S; Choudhury, Yukti Y; Chan, Jason Yongsheng JY; Tan, Puay Hoon PH; Tan, Min-Han MH; Teh, Bin Tean BT

Publication Date: 2022

Variant appearance in text: N/A

PubMed Link: 36213130

Variant Present in the following documents:

View BVdb publication page

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Genetic and Methylation Analysis of CTNNB1 in Benign and Malignant Melanocytic Lesions.

Cancers

Zaremba, Anne A; Jansen, Philipp P; Murali, Rajmohan R; Mayakonda, Anand A; Riedel, Anna A; Krahl, Dieter D; Burkhardt, Hans H; John, Stefan S; Géraud, Cyrill C; Philip, Manuel M; Kretz, Julia J; Möller, Inga I; Stadtler, Nadine N; Sucker, Antje A; Paschen, Annette A; Ugurel, Selma S; Zimmer, Lisa L; Livingstone, Elisabeth E; Horn, Susanne S; Plass, Christoph C; Schadendorf, Dirk D; Hadaschik, Eva E; Lutsik, Pavlo P; Griewank, Klaus K

Publication Date: 2022-08-23

Variant appearance in text: NRAS: Q61H

PubMed Link: 36077603

Variant Present in the following documents:

• Main text
• cancers-14-04066.pdf

View BVdb publication page

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Heterogeneous genetic and non-genetic mechanisms contribute to response and resistance to azacitidine monotherapy.

Ejhaem

Symeonidou, Vasiliki V; Metzner, Marlen M; Usukhbayar, Batchimeg B; Jackson, Aimee E AE; Fox, Sonia S; Craddock, Charles F CF; Vyas, Paresh P

Publication Date: 2022-08

Variant appearance in text: NRAS: Q61H

PubMed Link: 36051087

Variant Present in the following documents:

• JHA2-3-794-s003.xlsx, sheet 1

View BVdb publication page

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Detection of early seeding of Richter transformation in chronic lymphocytic leukemia.

Nature Medicine

Nadeu, Ferran F; Royo, Romina R; Massoni-Badosa, Ramon R; Playa-Albinyana, Heribert H; Garcia-Torre, Beatriz B; Duran-Ferrer, Martí M; Dawson, Kevin J KJ; Kulis, Marta M; Diaz-Navarro, Ander A; Villamor, Neus N; Melero, Juan L JL; Chapaprieta, Vicente V; Dueso-Barroso, Ana A; Delgado, Julio J; Moia, Riccardo R; Ruiz-Gil, Sara S; Marchese, Domenica D; Giró, Ariadna A; Verdaguer-Dot, Núria N; Romo, Mónica M; Clot, Guillem G; Rozman, Maria M; Frigola, Gerard G; Rivas-Delgado, Alfredo A; Baumann, Tycho T; Alcoceba, Miguel M; González, Marcos M; Climent, Fina F; Abrisqueta, Pau P; Castellví, Josep J; Bosch, Francesc F; Aymerich, Marta M; Enjuanes, Anna A; Ruiz-Gaspà, Sílvia S; López-Guillermo, Armando A; Jares, Pedro P; Beà, Sílvia S; Capella-Gutierrez, Salvador S; Gelpí, Josep Ll JL; López-Bigas, Núria N; Torrents, David D; Campbell, Peter J PJ; Gut, Ivo I; Rossi, Davide D; Gaidano, Gianluca G; Puente, Xose S XS; Garcia-Roves, Pablo M PM; Colomer, Dolors D; Heyn, Holger H; Maura, Francesco F; Martín-Subero, José I JI; Campo, Elías E

Publication Date: 2022-08

Variant appearance in text: NRAS: 183A>T; Gln61His

PubMed Link: 35953718

Variant Present in the following documents:

• 41591_2022_1927_MOESM3_ESM.xlsx, sheet 21

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Molecular characterization of colorectal cancer related peritoneal metastatic disease.

Nature Communications

Lenos, Kristiaan J KJ; Bach, Sander S; Ferreira Moreno, Leandro L; Ten Hoorn, Sanne S; Sluiter, Nina R NR; Bootsma, Sanne S; Vieira Braga, Felipe A FA; Nijman, Lisanne E LE; van den Bosch, Tom T; Miedema, Daniel M DM; van Dijk, Erik E; Ylstra, Bauke B; Kulicke, Ruth R; Davis, Fred P FP; Stransky, Nicolas N; Smolen, Gromoslaw A GA; Coebergh van den Braak, Robert R J RRJ; IJzermans, Jan N M JNM; Martens, John W M JWM; Hallam, Sally S; Beggs, Andrew D AD; Kops, Geert J P L GJPL; Lansu, Nico N; Bastiaenen, Vivian P VP; Klaver, Charlotte E L CEL; Lecca, Maria C MC; El Makrini, Khalid K; Elbers, Clara C CC; Dings, Mark P G MPG; van Noesel, Carel J M CJM; Kranenburg, Onno O; Medema, Jan Paul JP; Koster, Jan J; Koens, Lianne L; Punt, Cornelis J A CJA; Tanis, Pieter J PJ; de Hingh, Ignace H IH; Bijlsma, Maarten F MF; Tuynman, Jurriaan B JB; Vermeulen, Louis L

Publication Date: 2022-08-04

Variant appearance in text: N/A

PubMed Link: 35927254

Variant Present in the following documents:

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Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial.

Leukemia

Jahn, Nikolaus N; Jahn, Ekaterina E; Saadati, Maral M; Bullinger, Lars L; Larson, Richard A RA; Ottone, Tiziana T; Amadori, Sergio S; Prior, Thomas W TW; Brandwein, Joseph M JM; Appelbaum, Frederick R FR; Medeiros, Bruno C BC; Tallman, Martin S MS; Ehninger, Gerhard G; Heuser, Michael M; Ganser, Arnold A; Pallaud, Celine C; Gathmann, Insa I; Krzykalla, Julia J; Benner, Axel A; Bloomfield, Clara D CD; Thiede, Christian C; Stone, Richard M RM; Döhner, Hartmut H; Döhner, Konstanze K

Publication Date: 2022-09

Variant appearance in text: NRAS: Q61H

PubMed Link: 35922444

Variant Present in the following documents:

• 41375_2022_1650_MOESM2_ESM.xlsx, sheet 1

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Exploiting gene dependency to inform drug development for multiple myeloma.

Scientific Reports

Went, Molly M; Hoang, Phuc H PH; Law, Philip J PJ; Kaiser, Martin F MF; Houlston, Richard S RS

Publication Date: 2022-07-26

Variant appearance in text: N/A

PubMed Link: 35882937

Variant Present in the following documents:

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Identification of cell type-specific correlations between ERK activity and cell viability upon treatment with ERK1/2 inhibitors.

The Journal Of Biological Chemistry

Lebedev, Timofey D TD; Khabusheva, Elmira R ER; Mareeva, Sofia R SR; Ivanenko, Karina A KA; Morozov, Alexey V AV; Spirin, Pavel V PV; Rubtsov, Petr M PM; Snezhkina, Anastasiya V AV; Kudryavtseva, Anna V AV; Sorokin, Maxim I MI; Buzdin, Anton A AA; Prassolov, Vladimir S VS

Publication Date: 2022-08

Variant appearance in text: NRAS: Q61H

PubMed Link: 35787369

Variant Present in the following documents:

• Main text
• main.pdf

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Correlation of changes in subclonal architecture with progression in the MMRF CoMMpass study.

Translational Oncology

Kaur, Gurvinder G; Jena, Lingaraja L; Gupta, Ritu R; Farswan, Akanksha A; Gupta, Anubha A; Sriram, K K

Publication Date: 2022-06-28

Variant appearance in text: NRAS: 183A>T; Gln61His

PubMed Link: 35777247

Variant Present in the following documents:

• mmc5.xls, sheet 3

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The genetic heterogeneity and drug resistance mechanisms of relapsed refractory multiple myeloma.

Nature Communications

Vo, Josh N JN; Wu, Yi-Mi YM; Mishler, Jeanmarie J; Hall, Sarah S; Mannan, Rahul R; Wang, Lisha L; Ning, Yu Y; Zhou, Jin J; Hopkins, Alexander C AC; Estill, James C JC; Chan, Wallace K B WKB; Yesil, Jennifer J; Cao, Xuhong X; Rao, Arvind A; Tsodikov, Alexander A; Talpaz, Moshe M; Cole, Craig E CE; Ye, Jing C JC; , ; Bergsagel, P Leif PL; Auclair, Daniel D; Cho, Hearn Jay HJ; Robinson, Dan R DR; Chinnaiyan, Arul M AM

Publication Date: 2022-06-29

Variant appearance in text: NRAS: 183A>T; rs121913255

PubMed Link: 35768438

Variant Present in the following documents:

• 41467_2022_31430_MOESM4_ESM.xlsx, sheet 1

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Integrated genomic analyses of acral and mucosal melanomas nominate novel driver genes.

Genome Medicine

Wang, Meng M; Banik, Ishani I; Shain, A Hunter AH; Yeh, Iwei I; Bastian, Boris C BC

Publication Date: 2022-06-16

Variant appearance in text: N/A

PubMed Link: 35706047

Variant Present in the following documents:

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Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications

Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX

Publication Date: 2022-06-15

Variant appearance in text: N/A

PubMed Link: 35705558

Variant Present in the following documents:

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Rare presentation of multiple thromboses in Erdheim-Chester disease: a case-based review.

International Journal Of Hematology

Liu, Yongchang Y; Huang, Changpin C; Meng, Xiaohu X; Fang, Xin X; Xie, Xupin X; Wang, Changrong C; Wang, Meiyun M

Publication Date: 2022-11

Variant appearance in text: NRAS: Q61H

PubMed Link: 35687294

Variant Present in the following documents:

• Main text
• 12185_2022_Article_3393.pdf

View BVdb publication page

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Enhanced BRAF engagement by NRAS mutants capable of promoting melanoma initiation.

Nature Communications

Murphy, Brandon M BM; Terrell, Elizabeth M EM; Chirasani, Venkat R VR; Weiss, Tirzah J TJ; Lew, Rachel E RE; Holderbaum, Andrea M AM; Dhakal, Aastha A; Posada, Valentina V; Fort, Marie M; Bodnar, Michael S MS; Carey, Leiah M LM; Chen, Min M; Burd, Craig J CJ; Coppola, Vincenzo V; Morrison, Deborah K DK; Campbell, Sharon L SL; Burd, Christin E CE

Publication Date: 2022-06-07

Variant appearance in text: NRAS: Q61H

PubMed Link: 35672316

Variant Present in the following documents:

• 41467_2022_30881_MOESM5_ESM.xlsx, sheet 2
• 41467_2022_30881_MOESM5_ESM.xlsx, sheet 1
• 41467_2022_30881_MOESM4_ESM.xlsx, sheet 1
• 41467_2022_30881_MOESM8_ESM.xlsx, sheet 17
• 41467_2022_30881_MOESM6_ESM.xlsx, sheet 1
• 41467_2022_30881_MOESM8_ESM.xlsx, sheet 18

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Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence.

Leukemia

Misund, Kristine K; Hofste Op Bruinink, Davine D; Coward, Eivind E; Hoogenboezem, Remco M RM; Rustad, Even Holth EH; Sanders, Mathijs A MA; Rye, Morten M; Sponaas, Anne-Marit AM; van der Holt, Bronno B; Zweegman, Sonja S; Hovig, Eivind E; Meza-Zepeda, Leonardo A LA; Sundan, Anders A; Myklebost, Ola O; Sonneveld, Pieter P; Waage, Anders A

Publication Date: 2022-07

Variant appearance in text: N/A

PubMed Link: 35643867

Variant Present in the following documents:

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