Publications:

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Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications

Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G

Publication Date: 2023-03-11

Variant appearance in text: NRAS: Q61Q

PubMed Link: 36906579

Variant Present in the following documents:

• 41467_2023_36922_MOESM4_ESM.xls, sheet 2

View BVdb publication page

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Prevalence and patterns of mutations in RAS/RAF/MEK/ERK/MAPK signaling pathway in colorectal cancer in North Africa.

Bmc Cancer

Jafari, Meryem M; Laraqui, Abdelilah A; Baba, Walid W; Benmokhtar, Soukaina S; Zaitouni, Sara El SE; Ali, Abdelmounaim Ait AA; Bounaim, Ahmed A; Moujahid, Mountassir M; Tanz, Rachid R; Mahfoud, Tarik T; Sbitti, Yassir Y; Annaz, Hicham El HE; Abi, Rachid R; Tagajdid, Mohamed Rida MR; Kochri, Safae El SE; Lahlou, Idriss Amine IA; Hsaini, Houda El HE; Belayachi, Lamiae L; Benjouad, Abdelaziz A; Ichou, Mohammed M; En-Nya, Amina A; Ennibi, Khalid K

Publication Date: 2022-11-07

Variant appearance in text: NRAS: 183A>G

PubMed Link: 36344948

Variant Present in the following documents:

• 12885_2022_Article_10235.pdf

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Enhanced BRAF engagement by NRAS mutants capable of promoting melanoma initiation.

Nature Communications

Murphy, Brandon M BM; Terrell, Elizabeth M EM; Chirasani, Venkat R VR; Weiss, Tirzah J TJ; Lew, Rachel E RE; Holderbaum, Andrea M AM; Dhakal, Aastha A; Posada, Valentina V; Fort, Marie M; Bodnar, Michael S MS; Carey, Leiah M LM; Chen, Min M; Burd, Craig J CJ; Coppola, Vincenzo V; Morrison, Deborah K DK; Campbell, Sharon L SL; Burd, Christin E CE

Publication Date: 2022-06-07

Variant appearance in text: NRAS: Q61Q

PubMed Link: 35672316

Variant Present in the following documents:

• 41467_2022_30881_MOESM1_ESM.pdf
• 41467_2022_30881_MOESM2_ESM.pdf
• 41467_2022_30881_MOESM4_ESM.xlsx, sheet 1
• 41467_2022_30881_MOESM3_ESM.pdf

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Case Report: The Added Value of Liquid Biopsy in Advanced Colorectal Cancer From Clinical Case Experiences.

Frontiers In Pharmacology

Ulivi, Paola P; Passardi, Alessandro A; Marisi, Giorgia G; Chiadini, Elisa E; Molinari, Chiara C; Canale, Matteo M; Pasini, Luigi L; Ferroni, Fabio F; Frassineti, Giovanni Luca GL; Bartolini, Giulia G; Monti, Manlio M

Publication Date: 2021

Variant appearance in text: NRAS: Q61Q

PubMed Link: 34858176

Variant Present in the following documents:

• Main text
• fphar-12-745701.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: NRAS: Q61Q

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: NRAS: 183A>G; Q61Q

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Clonal evolution in chronic lymphocytic leukemia is scant in relapsed but accelerated in refractory cases after chemo(immune) therapy.

Haematologica

Zapatka, Marc M; Tausch, Eugen E; Öztürk, Selcen S; Yosifov, Deyan Yordanov DY; Seiffert, Martina M; Zenz, Thorsten T; Schneider, Christof C; Blöhdorn, Johannes J; Döhner, Hartmut H; Mertens, Daniel D; Lichter, Peter P; Stilgenbauer, Stephan S

Publication Date: 2022-03-01

Variant appearance in text: NRAS: 183A>G; Q61Q

PubMed Link: 33691380

Variant Present in the following documents:

• 2020_265777_ZAPATKA_TABS4.xlsx, sheet 1

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: NRAS: Q61Q

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival.

Cell Death & Disease

Lee, Erinna F EF; Harris, Tiffany J TJ; Tran, Sharon S; Evangelista, Marco M; Arulananda, Surein S; John, Thomas T; Ramnac, Celeste C; Hobbs, Chloe C; Zhu, Haoran H; Gunasingh, Gency G; Segal, David D; Behren, Andreas A; Cebon, Jonathan J; Dobrovic, Alexander A; Mariadason, John M JM; Strasser, Andreas A; Rohrbeck, Leona L; Haass, Nikolas K NK; Herold, Marco J MJ; Fairlie, W Douglas WD

Publication Date: 2019-04-24

Variant appearance in text: NRAS: Q61Q

PubMed Link: 31019203

Variant Present in the following documents:

• 41419_2019_1568_MOESM1_ESM.pdf

View BVdb publication page

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KRAS and NRAS pyrosequencing screening in Tunisian colorectal cancer patients in 2015.

Heliyon

Jouini, Raja R; Ferchichi, Marwa M; BenBrahim, Ehsen E; Ayari, Imen I; Khanchel, Fatma F; Koubaa, Wafa W; Saidi, Olfa O; Allani, Riadh R; Chadli-Debbiche, Aschraf A

Publication Date: 2019-03

Variant appearance in text: NRAS: Q61Q

PubMed Link: 30949599

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: NRAS: Q61Q

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 1

View BVdb publication page

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Lung cancer mutation testing: a clinical retesting study of agreement between a real-time PCR and a mass spectrometry test.

Oncotarget

Shepherd, Phillip P; Sheath, Karen L KL; Tin, Sandar Tin ST; Khwaounjoo, Prashannata P; Aye, Phyu S PS; Li, Angie A; Laking, George R GR; Kingston, Nicola J NJ; Lewis, Christopher A CA; Mark Elwood, J J; Love, Donald R DR; McKeage, Mark J MJ

Publication Date: 2017-11-24

Variant appearance in text: NRAS: Q61Q

PubMed Link: 29254176

Variant Present in the following documents:

• Main text
• oncotarget-08-101437.pdf

View BVdb publication page

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Molecular characterization of circulating colorectal tumor cells defines genetic signatures for individualized cancer care.

Oncotarget

Kong, Say Li SL; Liu, Xingliang X; Suhaimi, Nur-Afidah Mohamed NM; Koh, Kenneth Jia Hao KJH; Hu, Min M; Lee, Daniel Yoke San DYS; Cima, Igor I; Phyo, Wai Min WM; Lee, Esther Xing Wei EXW; Tai, Joyce A JA; Foong, Yu Miin YM; Vo, Jess Honganh JH; Koh, Poh Koon PK; Zhang, Tong T; Ying, Jackie Y JY; Lim, Bing B; Tan, Min-Han MH; Hillmer, Axel M AM

Publication Date: 2017-09-15

Variant appearance in text: NRAS: Q61Q

PubMed Link: 28978093

Variant Present in the following documents:

• oncotarget-08-68026-s002.xlsx, sheet 3

View BVdb publication page

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Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications

Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ

Publication Date: 2017-08-04

Variant appearance in text: NRAS: 183A>G; Q61Q

PubMed Link: 28775315

Variant Present in the following documents:

• 41467_2017_289_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: NRAS: Q61Q

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

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Diagnostic value of H3F3A mutations in giant cell tumour of bone compared to osteoclast-rich mimics.

The Journal Of Pathology. Clinical Research

Presneau, Nadège N; Baumhoer, Daniel D; Behjati, Sam S; Pillay, Nischalan N; Tarpey, Patrick P; Campbell, Peter J PJ; Jundt, Gernot G; Hamoudi, Rifat R; Wedge, David C DC; Loo, Peter Van PV; Hassan, A Bassim AB; Khatri, Bhavisha B; Ye, Hongtao H; Tirabosco, Roberto R; Amary, M Fernanda MF; Flanagan, Adrienne M AM

Publication Date: 2015-04

Variant appearance in text: NRAS: 183A>G; Q61Q

PubMed Link: 27499898

Variant Present in the following documents:

• CJP2-1-113-s004.xlsx, sheet 1

View BVdb publication page

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Validation and Application of a Custom-Designed Targeted Next-Generation Sequencing Panel for the Diagnostic Mutational Profiling of Solid Tumors.

Plos One

Froyen, Guy G; Broekmans, An A; Hillen, Femke F; Pat, Karin K; Achten, Ruth R; Mebis, Jeroen J; Rummens, Jean-Luc JL; Willemse, Johan J; Maes, Brigitte B

Publication Date: 2016

Variant appearance in text: NRAS: Q61Q

PubMed Link: 27101000

Variant Present in the following documents:

• Main text
• pone.0154038.pdf

View BVdb publication page

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Integrated digital error suppression for improved detection of circulating tumor DNA.

Nature Biotechnology

Newman, Aaron M AM; Lovejoy, Alexander F AF; Klass, Daniel M DM; Kurtz, David M DM; Chabon, Jacob J JJ; Scherer, Florian F; Stehr, Henning H; Liu, Chih Long CL; Bratman, Scott V SV; Say, Carmen C; Zhou, Li L; Carter, Justin N JN; West, Robert B RB; Sledge, George W GW; Shrager, Joseph B JB; Loo, Billy W BW; Neal, Joel W JW; Wakelee, Heather A HA; Diehn, Maximilian M; Alizadeh, Ash A AA

Publication Date: 2016-05

Variant appearance in text: NRAS: 183A>G; Q61Q

PubMed Link: 27018799

Variant Present in the following documents:

• NIHMS764326-supplement-6.xlsx, sheet 1

View BVdb publication page

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Recurrent inactivating RASA2 mutations in melanoma.

Nature Genetics

Arafeh, Rand R; Qutob, Nouar N; Emmanuel, Rafi R; Keren-Paz, Alona A; Madore, Jason J; Elkahloun, Abdel A; Wilmott, James S JS; Gartner, Jared J JJ; Di Pizio, Antonella A; Winograd-Katz, Sabina S; Sindiri, Sivasish S; Rotkopf, Ron R; Dutton-Regester, Ken K; Johansson, Peter P; Pritchard, Antonia L AL; Waddell, Nicola N; Hill, Victoria K VK; Lin, Jimmy C JC; Hevroni, Yael Y; Rosenberg, Steven A SA; Khan, Javed J; Ben-Dor, Shifra S; Niv, Masha Y MY; Ulitsky, Igor I; Mann, Graham J GJ; Scolyer, Richard A RA; Hayward, Nicholas K NK; Samuels, Yardena Y

Publication Date: 2015-12

Variant appearance in text: NRAS: Q61Q

PubMed Link: 26502337

Variant Present in the following documents:

• NIHMS65345-supplement-Supplementary_table_3.xlsx, sheet 1
• NIHMS65345-supplement-Supplementary_table_3.xlsx, sheet 2

View BVdb publication page

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BRAF and RAS mutations as prognostic factors in metastatic colorectal cancer patients undergoing liver resection.

British Journal Of Cancer

Schirripa, M M; Bergamo, F F; Cremolini, C C; Casagrande, M M; Lonardi, S S; Aprile, G G; Yang, D D; Marmorino, F F; Pasquini, G G; Sensi, E E; Lupi, C C; De Maglio, G G; Borrelli, N N; Pizzolitto, S S; Fasola, G G; Bertorelle, R R; Rugge, M M; Fontanini, G G; Zagonel, V V; Loupakis, F F; Falcone, A A

Publication Date: 2015-06-09

Variant appearance in text: NRAS: Q61Q

PubMed Link: 25942399

Variant Present in the following documents:

View BVdb publication page

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A highly recurrent RPS27 5'UTR mutation in melanoma.

Oncotarget

Dutton-Regester, Ken K; Gartner, Jared J JJ; Emmanuel, Rafi R; Qutob, Nouar N; Davies, Michael A MA; Gershenwald, Jeffrey E JE; Robinson, William W; Robinson, Steven S; Rosenberg, Steven A SA; Scolyer, Richard A RA; Mann, Graham J GJ; Thompson, John F JF; Hayward, Nicholas K NK; Samuels, Yardena Y

Publication Date: 2014-05-30

Variant appearance in text: NRAS: Q61Q

PubMed Link: 24913145

Variant Present in the following documents:

• oncotarget-05-2912-s003.xlsx, sheet 1

View BVdb publication page

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Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences.

Oncogene

Pugh, T J TJ; Yu, W W; Yang, J J; Field, A L AL; Ambrogio, L L; Carter, S L SL; Cibulskis, K K; Giannikopoulos, P P; Kiezun, A A; Kim, J J; McKenna, A A; Nickerson, E E; Getz, G G; Hoffher, S S; Messinger, Y H YH; Dehner, L P LP; Roberts, C W M CW; Rodriguez-Galindo, C C; Williams, G M GM; Rossi, C T CT; Meyerson, M M; Hill, D A DA

Publication Date: 2014-11-06

Variant appearance in text: NRAS: Q61Q

PubMed Link: 24909177

Variant Present in the following documents:

• onc2014150x7.xls, sheet 2

View BVdb publication page

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Development and validation of a clinical trial patient stratification assay that interrogates 27 mutation sites in MAPK pathway genes.

Plos One

Chang, Ken C N KC; Galuska, Stefan S; Weiner, Russell R; Marton, Matthew J MJ

Publication Date: 2013

Variant appearance in text: NRAS: Q61Q

PubMed Link: 23991070

Variant Present in the following documents:

• Main text
• pone.0072239.pdf

View BVdb publication page

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Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine.

Embo Molecular Medicine

Dias-Santagata, Dora D; Akhavanfard, Sara S; David, Serena S SS; Vernovsky, Kathy K; Kuhlmann, Georgiana G; Boisvert, Susan L SL; Stubbs, Hannah H; McDermott, Ultan U; Settleman, Jeffrey J; Kwak, Eunice L EL; Clark, Jeffrey W JW; Isakoff, Steven J SJ; Sequist, Lecia V LV; Engelman, Jeffrey A JA; Lynch, Thomas J TJ; Haber, Daniel A DA; Louis, David N DN; Ellisen, Leif W LW; Borger, Darrell R DR; Iafrate, A John AJ

Publication Date: 2010-05

Variant appearance in text: NRAS: Q61Q

PubMed Link: 20432502

Variant Present in the following documents:

• emmm0002-0146-SD1.xls, sheet 2

View BVdb publication page

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