RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia.
The Journal Of Clinical Investigation
Ren, Jian-Gang JG; Xing, Bowen B; Lv, Kaosheng K; O'Keefe, Rachel A RA; Wu, Mengfang M; Wang, Ruoxing R; Bauer, Kaylyn M KM; Ghazaryan, Arevik A; Burslem, George M GM; Zhang, Jing J; O'Connell, Ryan M RM; Pillai, Vinodh V; Hexner, Elizabeth O EO; Philips, Mark R MR; Tong, Wei W
Profile of BRAFV600E, BRAFK601E, NRAS, HRAS, and KRAS Mutational Status, and Clinicopathological Characteristics of Papillary Thyroid Carcinoma in Indonesian National Referral Hospital.
The Application Of Clinical Genetics
Harahap, Agnes Stephanie AS; Subekti, Imam I; Panigoro, Sonar Soni SS; Asmarinah, ; Lisnawati, ; Werdhani, Retno Asti RA; Agustina, Hasrayati H; Khoirunnisa, Dina D; Mutmainnah, Mutiah M; Salinah, ; Siswoyo, Alvita Dewi AD; Ham, Maria Francisca MF
Signaling Switching from Hedgehog-GLI to MAPK Signaling Potentially Serves as a Compensatory Mechanism in Melanoma Cell Lines Resistant to GANT-61.
Biomedicines
Piteša, Nikolina N; Kurtović, Matea M; Bartoniček, Nenad N; Gkotsi, Danai S DS; Čonkaš, Josipa J; Petrić, Tina T; Musani, Vesna V; Ozretić, Petar P; Riobo-Del Galdo, Natalia A NA; Sabol, Maja M
The benefit of co-targeting PARP-1 and c-Met on the efficacy of radiotherapy in wild type BRAF melanoma.
Frontiers In Medicine
Sabbah, Malak M; Najem, Ahmad A; Vanderkerkhove, Christophe C; Kert, Fabien F; Jourani, Younes Y; Journe, Fabrice F; Awada, Ahmad A; Van Gestel, Dirk D; Ghanem, Ghanem E GE; Krayem, Mohammad M
Case report: Complete response of an anaplastic thyroid carcinoma patient with NRAS Q61R/BRAF D594N mutations to the triplet of dabrafenib, trametinib and PD-1 antibody.
Frontiers In Immunology
Gui, Lin L; Zhu, Yiming Y; Li, Xiaomo X; He, Xiaohui X; Ma, Tonghui T; Cai, Yi Y; Liu, Shaoyan S
Publication Date: 2023
Variant appearance in text: NRAS: 182A>G; Gln61Arg
Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Deep genomic characterization highlights complexities and prognostic markers of pediatric acute myeloid leukemia.
Communications Biology
Cheng, Chi-Keung CK; Yung, Yuk-Lin YL; Chan, Hoi-Yun HY; Leung, Kam-Tong KT; Chan, Kathy Y Y KYY; Leung, Alex W K AWK; Cheng, Frankie W T FWT; Li, Chi-Kong CK; Wan, Thomas S K TSK; Luo, Xi X; Pitts, Herbert-Augustus HA; Cheung, Joyce S JS; Chan, Natalie P H NPH; Ng, Margaret H L MHL
Publication Date: 2023-03-31
Variant appearance in text: NRAS: 182A>G; Q61R; rs11554290
Deciphering Selectivity Mechanism of BRD9 and TAF1(2) toward Inhibitors Based on Multiple Short Molecular Dynamics Simulations and MM-GBSA Calculations.
Molecules (Basel, Switzerland)
Wang, Lifei L; Wang, Yan Y; Yu, Yingxia Y; Liu, Dong D; Zhao, Juan J; Zhang, Lulu L
Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non-small Cell Lung Cancer.
Cancer Research Communications
Frank, Malene S MS; Andersen, Christina S A CSA; Ahlborn, Lise B LB; Pallisgaard, Niels N; Bodtger, Uffe U; Gehl, Julie J
The molecular and functional landscape of resistance to immune checkpoint blockade in melanoma.
Nature Communications
Lim, Su Yin SY; Shklovskaya, Elena E; Lee, Jenny H JH; Pedersen, Bernadette B; Stewart, Ashleigh A; Ming, Zizhen Z; Irvine, Mal M; Shivalingam, Brindha B; Saw, Robyn P M RPM; Menzies, Alexander M AM; Carlino, Matteo S MS; Scolyer, Richard A RA; Long, Georgina V GV; Rizos, Helen H
DICER1 RNase IIIb domain mutations trigger widespread miRNA dysregulation and MAPK activation in pediatric thyroid cancer.
Frontiers In Endocrinology
Ricarte-Filho, Julio C JC; Casado-Medrano, Victoria V; Reichenberger, Erin E; Spangler, Zachary Z; Scheerer, Michele M; Isaza, Amber A; Baran, Julia J; Patel, Tasleema T; MacFarland, Suzanne P SP; Brodeur, Garrett M GM; Stewart, Douglas R DR; Baloch, Zubair Z; Bauer, Andrew J AJ; Wasserman, Jonathan D JD; Franco, Aime T AT
Development of a Next-generation Sequencing-based Gene Panel Test to Detect Measurable Residual Disease in Acute Myeloid Leukemia.
Annals Of Laboratory Medicine
Kim, Jin Ju JJ; Jang, Ji Eun JE; Lee, Hyeon Ah HA; Park, Mi Ri MR; Kook, Hye Won HW; Lee, Seung-Tae ST; Choi, Jong Rak JR; Min, Yoo Hong YH; Shin, Saeam S; Cheong, June-Won JW
Network expansion of genetic associations defines a pleiotropy map of human cell biology.
Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Circulating tumour DNA analysis predicts relapse and improves risk stratification in primary refractory multiple myeloma.
Blood Cancer Journal
Mithraprabhu, Sridurga S; Reynolds, John J; Turner, Rose R; Quach, Hang H; Horvath, Noemi N; Kerridge, Ian I; Kalff, Anna A; Bergin, Krystal K; Hocking, Jay J; Yuen, Flora F; Khong, Tiffany T; Durie, Brian M BM; Spencer, Andrew A
BCL2L11 Induction Mediates Sensitivity to Src and MEK1/2 Inhibition in Thyroid Cancer.
Cancers
Rose, Madison M MM; Espinoza, Veronica L VL; Hoff, Katelyn J KJ; Pike, Laura A LA; Sharma, Vibha V; Hofmann, Marie-Claude MC; Tan, Aik Choon AC; Pozdeyev, Nikita N; Schweppe, Rebecca E RE