NRAS c.181C>G ;(p.Q61E)

Variant ID: 1-115256530-G-C

NM_002524.4(NRAS):c.181C>G;(p.Q61E)

This variant was identified in 77 publications

View GRCh38 version.




Publications:


Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications
Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G
Publication Date: 2023-03-11

Variant appearance in text: NRAS: Q61E; rs121913254
PubMed Link: 36906579
Variant Present in the following documents:
  • 41467_2023_36922_MOESM4_ESM.xls, sheet 2
View BVdb publication page



High-risk multiple myeloma predicted by circulating plasma cells and its genetic characteristics.

Frontiers In Oncology
Xia, Yuan Y; Shen, Na N; Zhang, Run R; Wu, Yujie Y; Shi, Qinglin Q; Li, Jianyong J; Chen, Lijuan L; Xu, Min M; Jin, Yuanyuan Y
Publication Date: 2023

Variant appearance in text: rs121913254
PubMed Link: 36845679
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23

Variant appearance in text: NRAS: 181C>G; Gln61Glu
PubMed Link: 36823319
Variant Present in the following documents:
  • 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



Role of RAS signaling in ovarian cancer.

F1000Research
Therachiyil, Lubna L; Anand, Anjana A; Azmi, Abdullah A; Bhat, Ajaz A; Korashy, Hesham M HM; Uddin, Shahab S
Publication Date: 2022

Variant appearance in text: NRAS: Q61E
PubMed Link: 36451660
Variant Present in the following documents:
  • Main text
  • f1000research-11-138739.pdf
View BVdb publication page



Prevalence and patterns of mutations in RAS/RAF/MEK/ERK/MAPK signaling pathway in colorectal cancer in North Africa.

Bmc Cancer
Jafari, Meryem M; Laraqui, Abdelilah A; Baba, Walid W; Benmokhtar, Soukaina S; Zaitouni, Sara El SE; Ali, Abdelmounaim Ait AA; Bounaim, Ahmed A; Moujahid, Mountassir M; Tanz, Rachid R; Mahfoud, Tarik T; Sbitti, Yassir Y; Annaz, Hicham El HE; Abi, Rachid R; Tagajdid, Mohamed Rida MR; Kochri, Safae El SE; Lahlou, Idriss Amine IA; Hsaini, Houda El HE; Belayachi, Lamiae L; Benjouad, Abdelaziz A; Ichou, Mohammed M; En-Nya, Amina A; Ennibi, Khalid K
Publication Date: 2022-11-07

Variant appearance in text: NRAS: 181C>G; Gln61Glu
PubMed Link: 36344948
Variant Present in the following documents:
  • 12885_2022_Article_10235.pdf
View BVdb publication page



TLS/FUS-ERG fusion gene in acute leukemia and myelodysplastic syndrome evolved to acute leukemia: report of six cases and a literature review.

Annals Of Hematology
Zhang, Heyang H; Zhan, Qianru Q; Wang, Xiaoxue X; Gao, Feng F; Yu, Jinxiang J; Wang, Jing J; Fu, Wei W; Wang, Pingping P; Wei, Xin X; Zhang, Lijun L
Publication Date: 2022-12

Variant appearance in text: rs121913254
PubMed Link: 36181538
Variant Present in the following documents:
  • Main text
  • 277_2022_Article_4979.pdf
View BVdb publication page



Evolution of intra-tumoral heterogeneity across different pathological stages in papillary thyroid carcinoma.

Cancer Cell International
Affinito, Ornella O; Orlandella, Francesca Maria FM; Luciano, Neila N; Salvatore, Marco M; Salvatore, Giuliana G; Franzese, Monica M
Publication Date: 2022-08-22

Variant appearance in text: rs121913254
PubMed Link: 35996174
Variant Present in the following documents:
  • 12935_2022_2680_MOESM5_ESM.xlsx, sheet 5
View BVdb publication page



Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology
Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M
Publication Date: 2022

Variant appearance in text: NRAS: 181C>G; Q61E; rs121913254
PubMed Link: 35936718
Variant Present in the following documents:
  • Table_4.xlsx, sheet 2
View BVdb publication page



Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research
Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL
Publication Date: 2022-05

Variant appearance in text: rs121913254
PubMed Link: 35229492
Variant Present in the following documents:
  • PCMR-35-369-s003.xlsx, sheet 6
View BVdb publication page



KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One
Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW
Publication Date: 2022

Variant appearance in text: rs121913254
PubMed Link: 35081118
Variant Present in the following documents:
  • pone.0251286.s005.xlsx, sheet 8
View BVdb publication page



KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One
Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW
Publication Date: 2022

Variant appearance in text: rs121913254
PubMed Link: 35081118
Variant Present in the following documents:
  • pone.0251286.s005.xlsx, sheet 8
View BVdb publication page



Enhanced interpretation of 935 hotspot and non-hotspot RAS variants using evidence-based structural bioinformatics.

Computational And Structural Biotechnology Journal
Tripathi, Swarnendu S; Dsouza, Nikita R NR; Mathison, Angela J AJ; Leverence, Elise E; Urrutia, Raul R; Zimmermann, Michael T MT
Publication Date: 2022

Variant appearance in text: NRAS: Q61E
PubMed Link: 34976316
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Concordance of acquired mutations between metastatic lesions and liquid biopsy in metastatic colorectal cancer.

Future Science Oa
Taniguchi, Fumitaka F; Nyuya, Akihiro A; Toshima, Toshiaki T; Yasui, Kazuya K; Mori, Yoshiko Y; Okawaki, Makoto M; Kishimoto, Hiroyuki H; Umeda, Yuzo Y; Fujiwara, Toshiyoshi T; Tanioka, Hiroaki H; Yamaguchi, Yoshiyuki Y; Goel, Ajay A; Nagasaka, Takeshi T
Publication Date: 2021-12

Variant appearance in text: NRAS: Q61E
PubMed Link: 34840814
Variant Present in the following documents:
  • Main text
  • fsoa-07-757.pdf
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: NRAS: Q61E
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Infrequent RAS mutation is not associated with specific histological phenotype in gliomas.

Bmc Cancer
Makino, Yasuhide Y; Arakawa, Yoshiki Y; Yoshioka, Ema E; Shofuda, Tomoko T; Minamiguchi, Sachiko S; Kawauchi, Takeshi T; Tanji, Masahiro M; Kanematsu, Daisuke D; Nonaka, Masahiro M; Okita, Yoshiko Y; Kodama, Yoshinori Y; Mano, Masayuki M; Hirose, Takanori T; Mineharu, Yohei Y; Miyamoto, Susumu S; Kanemura, Yonehiro Y
Publication Date: 2021-09-15

Variant appearance in text: NRAS: Q61E
PubMed Link: 34525976
Variant Present in the following documents:
  • Main text
  • 12885_2021_Article_8733.pdf
View BVdb publication page



Clinical Utility of Liquid Biopsy-Based Actionable Mutations Detected via ddPCR.

Biomedicines
Palacín-Aliana, Irina I; García-Romero, Noemí N; Asensi-Puig, Adrià A; Carrión-Navarro, Josefa J; González-Rumayor, Víctor V; Ayuso-Sacido, Ángel Á
Publication Date: 2021-07-28

Variant appearance in text: NRAS: Q61E
PubMed Link: 34440110
Variant Present in the following documents:
  • Main text
View BVdb publication page



Orthogonal MET analysis in a population-representative stage II-III colon cancer cohort: prognostic and potential therapeutic implications.

Molecular Oncology
Craig, Stephanie G SG; Mende, Svenja S; Humphries, Matthew P MP; Bingham, Victoria V; Viratham Pulsawatdi, Amélie A; Loughrey, Maurice B MB; Coleman, Helen G HG; McQuaid, Stephen S; Wilson, Richard H RH; Van Schaeybroeck, Sandra S; James, Jacqueline A JA; Salto-Tellez, Manuel M
Publication Date: 2021-12

Variant appearance in text: NRAS: Q61E
PubMed Link: 34428346
Variant Present in the following documents:
  • Main text
  • MOL2-15-3317.pdf
View BVdb publication page



Orthogonal MET analysis in a population-representative stage II-III colon cancer cohort: prognostic and potential therapeutic implications.

Molecular Oncology
Craig, Stephanie G SG; Mende, Svenja S; Humphries, Matthew P MP; Bingham, Victoria V; Viratham Pulsawatdi, Amélie A; Loughrey, Maurice B MB; Coleman, Helen G HG; McQuaid, Stephen S; Wilson, Richard H RH; Van Schaeybroeck, Sandra S; James, Jacqueline A JA; Salto-Tellez, Manuel M
Publication Date: 2021-12

Variant appearance in text: NRAS: Q61E
PubMed Link: 34428346
Variant Present in the following documents:
  • Main text
  • MOL2-15-3317.pdf
View BVdb publication page



Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer
Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA
Publication Date: 2021-05

Variant appearance in text: NRAS: 181C>G; Q61E
PubMed Link: 33704917
Variant Present in the following documents:
  • TCA-12-1271-s003.xls, sheet 1
View BVdb publication page



Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.

Nature Communications
Hartlieb, Sabine A SA; Sieverling, Lina L; Nadler-Holly, Michal M; Ziehm, Matthias M; Toprak, Umut H UH; Herrmann, Carl C; Ishaque, Naveed N; Okonechnikov, Konstantin K; Gartlgruber, Moritz M; Park, Young-Gyu YG; Wecht, Elisa Maria EM; Savelyeva, Larissa L; Henrich, Kai-Oliver KO; Rosswog, Carolina C; Fischer, Matthias M; Hero, Barbara B; Jones, David T W DTW; Pfaff, Elke E; Witt, Olaf O; Pfister, Stefan M SM; Volckmann, Richard R; Koster, Jan J; Kiesel, Katharina K; Rippe, Karsten K; Taschner-Mandl, Sabine S; Ambros, Peter P; Brors, Benedikt B; Selbach, Matthias M; Feuerbach, Lars L; Westermann, Frank F
Publication Date: 2021-02-24

Variant appearance in text: rs121913254
PubMed Link: 33627664
Variant Present in the following documents:
  • 41467_2021_21247_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: NRAS: 181C>G; Q61E
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
  • 41467_2020_20162_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Healthy Donors Harbor Memory T Cell Responses to RAS Neo-Antigens.

Cancers
Holmström, Morten Orebo MO; Andersen, Mads Hald MH
Publication Date: 2020-10-19

Variant appearance in text: NRAS: Q61E
PubMed Link: 33086698
Variant Present in the following documents:
  • Main text
  • cancers-12-03045.pdf
View BVdb publication page



Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports
Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O
Publication Date: 2020-10-13

Variant appearance in text: rs121913254
PubMed Link: 33051506
Variant Present in the following documents:
  • 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports
Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA
Publication Date: 2020-09-21

Variant appearance in text: NRAS: Q61E
PubMed Link: 32958805
Variant Present in the following documents:
  • 41598_2020_72404_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



Analysis of genetic alterations identifies the frequent mutation of GNAS in colorectal laterally spreading tumors.

Cancer Communications (London, England)
Nong, Yanying Y; Zhang, Yuru Y; Zhang, Yi Y; Pan, Lei L; Chen, Junsheng J; Zhu, Chaojun C; Han, Lu L; Li, Aimin A; Liu, Side S
Publication Date: 2020-11

Variant appearance in text: rs121913254
PubMed Link: 32762003
Variant Present in the following documents:
  • CAC2-40-636-s001.pdf
View BVdb publication page



Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine
Li, Jiaping J; Jiang, Wei W; Wei, Jinwang J; Zhang, Jianwei J; Cai, Linbo L; Luo, Minjie M; Wang, Zhan Z; Sun, Wending W; Wang, Shengzhou S; Wang, Chen C; Dai, Chun C; Liu, Jun J; Wang, Guan G; Wang, Jiping J; Xu, Qiang Q; Deng, Yanhong Y
Publication Date: 2020-08-01

Variant appearance in text: NRAS: 181C>G; Q61E
PubMed Link: 32738923
Variant Present in the following documents:
  • 12967_2020_2449_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Study of Ras Mutations' Prognostic Value in Metastatic Colorectal Cancer: STORIA Analysis.

Cancers
Ottaiano, Alessandro A; Normanno, Nicola N; Facchini, Sergio S; Cassata, Antonino A; Nappi, Anna A; Romano, Carmela C; Silvestro, Lucrezia L; De Stefano, Alfonso A; Rachiglio, Anna Maria AM; Roma, Cristin C; Maiello, Monica R MR; Scala, Stefania S; Delrio, Paolo P; Tatangelo, Fabiana F; Di Mauro, Annabella A; Botti, Gerardo G; Avallone, Antonio A; Nasti, Guglielmo G
Publication Date: 2020-07-16

Variant appearance in text: NRAS: Q61E
PubMed Link: 32708575
Variant Present in the following documents:
  • Main text
View BVdb publication page



Transcriptional downregulation of MHC class I and melanoma de- differentiation in resistance to PD-1 inhibition.

Nature Communications
Lee, Jenny H JH; Shklovskaya, Elena E; Lim, Su Yin SY; Carlino, Matteo S MS; Menzies, Alexander M AM; Stewart, Ashleigh A; Pedersen, Bernadette B; Irvine, Malama M; Alavi, Sara S; Yang, Jean Y H JYH; Strbenac, Dario D; Saw, Robyn P M RPM; Thompson, John F JF; Wilmott, James S JS; Scolyer, Richard A RA; Long, Georgina V GV; Kefford, Richard F RF; Rizos, Helen H
Publication Date: 2020-04-20

Variant appearance in text: NRAS: Q61E
PubMed Link: 32312968
Variant Present in the following documents:
  • 41467_2020_15726_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Pre-analytical factors affecting the establishment of a single tube assay for multiparameter liquid biopsy detection in melanoma patients.

Molecular Oncology
Schneegans, Svenja S; Lück, Lelia L; Besler, Katharina K; Bluhm, Leonie L; Stadler, Julia-Christina JC; Staub, Janina J; Greinert, Rüdiger R; Volkmer, Beate B; Kubista, Mikael M; Gebhardt, Christoffer C; Sartori, Alexander A; Irwin, Darryl D; Serkkola, Elina E; Af Hällström, Taija T; Lianidou, Evi E; Sprenger-Haussels, Markus M; Hussong, Melanie M; Mohr, Peter P; Schneider, Stefan W SW; Shaffer, Jonathan J; Pantel, Klaus K; Wikman, Harriet H
Publication Date: 2020-05

Variant appearance in text: NRAS: 181C>G; Q61E
PubMed Link: 32246814
Variant Present in the following documents:
  • MOL2-14-1001-s004.xlsx, sheet 1
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: NRAS: Q61E
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 11
View BVdb publication page



POT1 and Damage Response Malfunction Trigger Acquisition of Somatic Activating Mutations in the VEGF Pathway in Cardiac Angiosarcomas.

Journal Of The American Heart Association
Calvete, Oriol O; Garcia-Pavia, Pablo P; Domínguez, Fernando F; Mosteiro, Lluc L; Pérez-Cabornero, Lucía L; Cantalapiedra, Diego D; Zorio, Esther E; Ramón Y Cajal, Teresa T; Crespo-Leiro, Maria G MG; Teulé, Álex Á; Lázaro, Conxi C; Morente, Manuel M MM; Urioste, Miguel M; Benitez, Javier J
Publication Date: 2019-09-17

Variant appearance in text: rs121913254
PubMed Link: 31510873
Variant Present in the following documents:
  • JAH3-8-e012875-s001.pdf
  • JAH3-8-e012875.pdf
View BVdb publication page



Mutational concordance between primary and metastatic melanoma: a next-generation sequencing approach.

Journal Of Translational Medicine
Manca, Antonella A; Paliogiannis, Panagiotis P; Colombino, Maria M; Casula, Milena M; Lissia, Amelia A; Botti, Gerardo G; Caracò, Corrado C; Ascierto, Paolo A PA; Sini, Maria Cristina MC; Palomba, Grazia G; Pisano, Marina M; , ; , ; Doneddu, Valentina V; Cossu, Antonio A; Palmieri, Giuseppe G; ,
Publication Date: 2019-08-28

Variant appearance in text: rs121913254
PubMed Link: 31455347
Variant Present in the following documents:
  • 12967_2019_2039_MOESM1_ESM.xlsx, sheet 2
View BVdb publication page



RAS Mutation in Mucinous Carcinoma of the Ovary

Asian Pacific Journal Of Cancer Prevention : Apjcp
Panyavaranant, Pinyada P; Teerapakpinyo, Chinachote C; Pohthipornthawat, Natkrita N; Oranratanaphan, Shina S; Shuangshoti, Shanop S; Triratanachat, Surang S
Publication Date: 2019-04-29

Variant appearance in text: NRAS: Q61E
PubMed Link: 31030485
Variant Present in the following documents:
  • Main text
  • APJCP-20-1127.pdf
View BVdb publication page



Targeting the ERK Signaling Pathway in Melanoma.

International Journal Of Molecular Sciences
Savoia, Paola P; Fava, Paolo P; Casoni, Filippo F; Cremona, Ottavio O
Publication Date: 2019-03-25

Variant appearance in text: NRAS: 181C>G; Q61E
PubMed Link: 30934534
Variant Present in the following documents:
  • Main text
  • ijms-20-01483.pdf
View BVdb publication page



Clinical relevance of circulating tumor DNA assessed through deep sequencing in patients with metastatic colorectal cancer.

Cancer Medicine
Osumi, Hiroki H; Shinozaki, Eiji E; Takeda, Yoshinori Y; Wakatsuki, Takeru T; Ichimura, Takashi T; Saiura, Akio A; Yamaguchi, Kensei K; Takahashi, Shunji S; Noda, Tetsuo T; Zembutsu, Hitoshi H
Publication Date: 2019-01

Variant appearance in text: NRAS: Q61E
PubMed Link: 30575318
Variant Present in the following documents:
  • Main text
View BVdb publication page



Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways.

Journal Of Hematology & Oncology
Tessoulin, Benoît B; Moreau-Aubry, Agnès A; Descamps, Géraldine G; Gomez-Bougie, Patricia P; Maïga, Sophie S; Gaignard, Alban A; Chiron, David D; Ménoret, Emmanuelle E; Le Gouill, Steven S; Moreau, Philippe P; Amiot, Martine M; Pellat-Deceunynck, Catherine C
Publication Date: 2018-12-13

Variant appearance in text: rs121913254
PubMed Link: 30545397
Variant Present in the following documents:
  • 13045_2018_679_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Clinical Validation of Newly Developed Multiplex Kit Using Luminex xMAP Technology for Detecting Simultaneous RAS and BRAF Mutations in Colorectal Cancer: Results of the RASKET-B Study.

Neoplasia (New York, N.Y.)
Taniguchi, Hiroya H; Okamoto, Wataru W; Muro, Kei K; Akagi, Kiwamu K; Hara, Hiroki H; Nishina, Tomohiro T; Kajiwara, Takeshi T; Denda, Tadamichi T; Hironaka, Shuichi S; Kudo, Toshihiro T; Satoh, Taroh T; Yamanaka, Takeharu T; Abe, Yukiko Y; Fukushima, Yoshiyuki Y; Yoshino, Takayuki T
Publication Date: 2018-12

Variant appearance in text: NRAS: Q61E
PubMed Link: 30412858
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Water Distribution within Wild-Type NRas Protein and Q61 Mutants during Unrestrained QM/MM Dynamics.

Biophysical Journal
Tichauer, Ruth H RH; Favre, Gilles G; Cabantous, Stéphanie S; Landa, Georges G; Hemeryck, Anne A; Brut, Marie M
Publication Date: 2018-10-16

Variant appearance in text: N-ras: Q61E
PubMed Link: 30224050
Variant Present in the following documents:
  • Main text
View BVdb publication page



Fibroblast growth factor receptor 3 (FGFR3) aberrations in muscle-invasive urothelial carcinoma.

Bmc Urology
Kim, Young Saing YS; Kim, Kyung K; Kwon, Ghee-Young GY; Lee, Su Jin SJ; Park, Se Hoon SH
Publication Date: 2018-07-31

Variant appearance in text: NRAS: 181C>G; Q61E
PubMed Link: 30064409
Variant Present in the following documents:
  • 12894_2018_380_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Integrative omics analyses broaden treatment targets in human cancer.

Genome Medicine
Sengupta, Sohini S; Sun, Sam Q SQ; Huang, Kuan-Lin KL; Oh, Clara C; Bailey, Matthew H MH; Varghese, Rajees R; Wyczalkowski, Matthew A MA; Ning, Jie J; Tripathi, Piyush P; McMichael, Joshua F JF; Johnson, Kimberly J KJ; Kandoth, Cyriac C; Welch, John J; Ma, Cynthia C; Wendl, Michael C MC; Payne, Samuel H SH; Fenyö, David D; Townsend, Reid R RR; Dipersio, John F JF; Chen, Feng F; Ding, Li L
Publication Date: 2018-07-27

Variant appearance in text: NRAS: Q61E
PubMed Link: 30053901
Variant Present in the following documents:
  • 13073_2018_564_MOESM2_ESM.xlsx, sheet 3
View BVdb publication page



Clinical validation of the next-generation sequencing-based Extended RAS Panel assay using metastatic colorectal cancer patient samples from the phase 3 PRIME study.

Journal Of Cancer Research And Clinical Oncology
Udar, Nitin N; Lofton-Day, Catherine C; Dong, Jun J; Vavrek, Darcy D; Jung, A Scott AS; Meier, Kristen K; Iyer, Anita A; Slaughter, Ryan R; Gutekunst, Karen K; Bach, Bruce A BA; Peeters, Marc M; Douillard, Jean-Yves JY
Publication Date: 2018-10

Variant appearance in text: NRAS: Gln61Glu
PubMed Link: 30019318
Variant Present in the following documents:
  • 432_2018_2688_MOESM1_ESM.pdf
View BVdb publication page



Oncogene mutational analysis in Chinese gastrointestinal stromal tumor patients.

Oncotargets And Therapy
Chen, Qiong Q; Li, Rong R; Zhang, Zhi-Gao ZG; Deng, Qiao-Ting QT; Li, Kun K; Wang, Hao H; Yang, Xue-Xi XX; Wu, Ying-Song YS
Publication Date: 2018

Variant appearance in text: NRAS: Q61E
PubMed Link: 29719410
Variant Present in the following documents:
  • Main text
  • ott-11-2279.pdf
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Feasibility study of cancer genome alterations identified by next generation sequencing: ABC study.

Japanese Journal Of Clinical Oncology
Naito, Yoichi Y; Takahashi, Hideaki H; Shitara, Kohei K; Okamoto, Wataru W; Bando, Hideaki H; Kuwata, Takeshi T; Kuboki, Yasutoshi Y; Matsumoto, Shingo S; Miki, Izumi I; Yamanaka, Takeharu T; Watanabe, Atsushi A; Kojima, Motohiro M
Publication Date: 2018-06-01

Variant appearance in text: NRAS: 181C>G; Q61E
PubMed Link: 29659903
Variant Present in the following documents:
  • hyy052supplementaltable1ionver1.xls, sheet 1
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Discovery of coding regions in the human genome by integrated proteogenomics analysis workflow.

Nature Communications
Zhu, Yafeng Y; Orre, Lukas M LM; Johansson, Henrik J HJ; Huss, Mikael M; Boekel, Jorrit J; Vesterlund, Mattias M; Fernandez-Woodbridge, Alejandro A; Branca, Rui M M RMM; Lehtiö, Janne J
Publication Date: 2018-03-02

Variant appearance in text: rs121913254
PubMed Link: 29500430
Variant Present in the following documents:
  • 41467_2018_3311_MOESM5_ESM.xlsx, sheet 1
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Chromothripsis 18 in multiple myeloma patient with rapid extramedullary relapse.

Molecular Cytogenetics
Smetana, Jan J; Oppelt, Jan J; Štork, Martin M; Pour, Luděk L; Kuglík, Petr P
Publication Date: 2018

Variant appearance in text: rs121913254
PubMed Link: 29375670
Variant Present in the following documents:
  • 13039_2018_357_MOESM2_ESM.xlsx, sheet 1
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Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and Are Primed for Neoplastic Progression.

Molecular Cancer Research : Mcr
Drew, David A DA; Mo, Allen A; Grady, James J JJ; Stevens, Richard G RG; Levine, Joel B JB; Brenner, Bruce M BM; Anderson, Joseph C JC; Forouhar, Faripour F; O'Brien, Michael J MJ; Devers, Thomas J TJ; Rosenberg, Daniel W DW
Publication Date: 2018-03

Variant appearance in text: NRAS: Q61E
PubMed Link: 29222172
Variant Present in the following documents:
  • Main text
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Prevalence and detection of low-allele-fraction variants in clinical cancer samples.

Nature Communications
Shin, Hyun-Tae HT; Choi, Yoon-La YL; Yun, Jae Won JW; Kim, Nayoung K D NKD; Kim, Sook-Young SY; Jeon, Hyo Jeong HJ; Nam, Jae-Yong JY; Lee, Chung C; Ryu, Daeun D; Kim, Sang Cheol SC; Park, Kyunghee K; Lee, Eunjin E; Bae, Joon Seol JS; Son, Dae Soon DS; Joung, Je-Gun JG; Lee, Jeeyun J; Kim, Seung Tae ST; Ahn, Myung-Ju MJ; Lee, Se-Hoon SH; Ahn, Jin Seok JS; Lee, Woo Yong WY; Oh, Bo Young BY; Park, Yeon Hee YH; Lee, Jeong Eon JE; Lee, Kwang Hyuk KH; Kim, Hee Cheol HC; Kim, Kyoung-Mee KM; Im, Young-Hyuck YH; Park, Keunchil K; Park, Peter J PJ; Park, Woong-Yang WY
Publication Date: 2017-11-09

Variant appearance in text: NRAS: Q61E
PubMed Link: 29123093
Variant Present in the following documents:
  • 41467_2017_1470_MOESM11_ESM.xlsx, sheet 1
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Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications
Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ
Publication Date: 2017-08-04

Variant appearance in text: NRAS: 181C>G; Q61E
PubMed Link: 28775315
Variant Present in the following documents:
  • 41467_2017_289_MOESM7_ESM.xlsx, sheet 1
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Detecting protein variants by mass spectrometry: a comprehensive study in cancer cell-lines.

Genome Medicine
Alfaro, Javier A JA; Ignatchenko, Alexandr A; Ignatchenko, Vladimir V; Sinha, Ankit A; Boutros, Paul C PC; Kislinger, Thomas T
Publication Date: 2017-07-18

Variant appearance in text: NRAS: Q61E; rs121913254
PubMed Link: 28716134
Variant Present in the following documents:
  • 13073_2017_454_MOESM6_ESM.xlsx, sheet 1
  • 13073_2017_454_MOESM7_ESM.xlsx, sheet 1
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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: NRAS: Q61E; rs121913254
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
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Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Genome Research
Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U
Publication Date: 2017-04

Variant appearance in text: NRAS: 181C>G; Q61E
PubMed Link: 28179366
Variant Present in the following documents:
  • supp_gr.213546.116_Supplemental_Table_S7.xlsx, sheet 1
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Distribution bias analysis of germline and somatic single-nucleotide variations that impact protein functional site and neighboring amino acids.

Scientific Reports
Pan, Yang Y; Yan, Cheng C; Hu, Yu Y; Fan, Yu Y; Pan, Qing Q; Wan, Quan Q; Torcivia-Rodriguez, John J; Mazumder, Raja R
Publication Date: 2017-02-08

Variant appearance in text: NRAS: Q61E
PubMed Link: 28176830
Variant Present in the following documents:
  • Main text
  • srep42169.pdf
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Using a constraint-based regression method for relative quantification of somatic mutations in pyrosequencing signals: a case for NRAS analysis.

Algorithms For Molecular Biology : Amb
Ambroise, Jerome J; Badir, Jamal J; Nienhaus, Louise L; Robert, Annie A; Dekairelle, Anne-France AF; Gala, Jean-Luc JL
Publication Date: 2016

Variant appearance in text: NRAS: 181C>G; Q61E
PubMed Link: 27651826
Variant Present in the following documents:
  • Main text
  • 13015_2016_Article_86.pdf
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Genetic hierarchy and temporal variegation in the clonal history of acute myeloid leukaemia.

Nature Communications
Hirsch, Pierre P; Zhang, Yanyan Y; Tang, Ruoping R; Joulin, Virginie V; Boutroux, Hélène H; Pronier, Elodie E; Moatti, Hannah H; Flandrin, Pascale P; Marzac, Christophe C; Bories, Dominique D; Fava, Fanny F; Mokrani, Hayat H; Betems, Aline A; Lorre, Florence F; Favier, Rémi R; Féger, Frédéric F; Mohty, Mohamad M; Douay, Luc L; Legrand, Ollivier O; Bilhou-Nabera, Chrystèle C; Louache, Fawzia F; Delhommeau, François F
Publication Date: 2016-08-18

Variant appearance in text: NRAS: 181C>G; Q61E
PubMed Link: 27534895
Variant Present in the following documents:
  • ncomms12475-s2.xlsx, sheet 1
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Cardiogenic Shock and Respiratory Failure in a Patient With Metastatic Melanoma Receiving Trametinib Therapy.

The Oncologist
Tseng, Diane D; Mason, Xenos L XL; Neilan, Tomas G TG; Sullivan, Ryan J RJ
Publication Date: 2016-09

Variant appearance in text: NRAS: Q61E
PubMed Link: 27388234
Variant Present in the following documents:
  • Main text
View BVdb publication page



Integrated digital error suppression for improved detection of circulating tumor DNA.

Nature Biotechnology
Newman, Aaron M AM; Lovejoy, Alexander F AF; Klass, Daniel M DM; Kurtz, David M DM; Chabon, Jacob J JJ; Scherer, Florian F; Stehr, Henning H; Liu, Chih Long CL; Bratman, Scott V SV; Say, Carmen C; Zhou, Li L; Carter, Justin N JN; West, Robert B RB; Sledge, George W GW; Shrager, Joseph B JB; Loo, Billy W BW; Neal, Joel W JW; Wakelee, Heather A HA; Diehn, Maximilian M; Alizadeh, Ash A AA
Publication Date: 2016-05

Variant appearance in text: NRAS: 181C>G; Q61E
PubMed Link: 27018799
Variant Present in the following documents:
  • NIHMS764326-supplement-6.xlsx, sheet 1
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Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in non-small cell lung cancer.

Oncotarget
Xu, Naiqing N; Fang, Wenfeng W; Mu, Libing L; Tang, Yanna Y; Gao, Lei L; Ren, Shengxiang S; Cao, Dengfeng D; Zhou, Lixin L; Zhang, Aiqun A; Liu, Deruo D; Zhou, Caicun C; Wong, Kwok-Kin KK; Yu, Lei L; Zhang, Li L; Chen, Liang L
Publication Date: 2016-01-26

Variant appearance in text: NRAS: Q61E
PubMed Link: 26646697
Variant Present in the following documents:
  • oncotarget-07-3884-s001.pdf
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Mutational profiling of brain metastasis from breast cancer: matched pair analysis of targeted sequencing between brain metastasis and primary breast cancer.

Oncotarget
Lee, Ji Yun JY; Park, Kyunghee K; Lim, Sung Hee SH; Kim, Hae Su HS; Yoo, Kwai Han KH; Jung, Ki Sun KS; Song, Haa-Na HN; Hong, Mineui M; Do, In-Gu IG; Ahn, TaeJin T; Lee, Se Kyung SK; Bae, Soo Youn SY; Kim, Seok Won SW; Lee, Jeong Eon JE; Nam, Seok Jin SJ; Kim, Duk-Hwan DH; Jung, Hae Hyun HH; Kim, Ji-Yeon JY; Ahn, Jin Seok JS; Im, Young-Hyuck YH; Park, Yeon Hee YH
Publication Date: 2015-12-22

Variant appearance in text: NRAS: 181C>G; Q61E
PubMed Link: 26527317
Variant Present in the following documents:
  • oncotarget-06-43731-s002.xlsx, sheet 1
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Recurrent inactivating RASA2 mutations in melanoma.

Nature Genetics
Arafeh, Rand R; Qutob, Nouar N; Emmanuel, Rafi R; Keren-Paz, Alona A; Madore, Jason J; Elkahloun, Abdel A; Wilmott, James S JS; Gartner, Jared J JJ; Di Pizio, Antonella A; Winograd-Katz, Sabina S; Sindiri, Sivasish S; Rotkopf, Ron R; Dutton-Regester, Ken K; Johansson, Peter P; Pritchard, Antonia L AL; Waddell, Nicola N; Hill, Victoria K VK; Lin, Jimmy C JC; Hevroni, Yael Y; Rosenberg, Steven A SA; Khan, Javed J; Ben-Dor, Shifra S; Niv, Masha Y MY; Ulitsky, Igor I; Mann, Graham J GJ; Scolyer, Richard A RA; Hayward, Nicholas K NK; Samuels, Yardena Y
Publication Date: 2015-12

Variant appearance in text: NRAS: Q61E; rs121913254
PubMed Link: 26502337
Variant Present in the following documents:
  • NIHMS65345-supplement-Supplementary_table_3.xlsx, sheet 1
  • NIHMS65345-supplement-Supplementary_table_3.xlsx, sheet 2
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Detection of KRAS, NRAS and BRAF by mass spectrometry - a sensitive, reliable, fast and cost-effective technique.

Diagnostic Pathology
Kriegsmann, Mark M; Arens, Norbert N; Endris, Volker V; Weichert, Wilko W; Kriegsmann, Jörg J
Publication Date: 2015-07-30

Variant appearance in text: NRAS: Q61E
PubMed Link: 26220423
Variant Present in the following documents:
  • Main text
View BVdb publication page



Clinical Validation of a Multiplex Kit for RAS Mutations in Colorectal Cancer: Results of the RASKET (RAS KEy Testing) Prospective, Multicenter Study.

Ebiomedicine
Yoshino, Takayuki T; Muro, Kei K; Yamaguchi, Kensei K; Nishina, Tomohiro T; Denda, Tadamichi T; Kudo, Toshihiro T; Okamoto, Wataru W; Taniguchi, Hiroya H; Akagi, Kiwamu K; Kajiwara, Takeshi T; Hironaka, Shuichi S; Satoh, Taroh T
Publication Date: 2015-04

Variant appearance in text: NRAS: Q61E
PubMed Link: 26137573
Variant Present in the following documents:
  • Main text
View BVdb publication page



BRAF and RAS mutations as prognostic factors in metastatic colorectal cancer patients undergoing liver resection.

British Journal Of Cancer
Schirripa, M M; Bergamo, F F; Cremolini, C C; Casagrande, M M; Lonardi, S S; Aprile, G G; Yang, D D; Marmorino, F F; Pasquini, G G; Sensi, E E; Lupi, C C; De Maglio, G G; Borrelli, N N; Pizzolitto, S S; Fasola, G G; Bertorelle, R R; Rugge, M M; Fontanini, G G; Zagonel, V V; Loupakis, F F; Falcone, A A
Publication Date: 2015-06-09

Variant appearance in text: NRAS: Q61E
PubMed Link: 25942399
Variant Present in the following documents:
View BVdb publication page