NRAS c.169G>A ;(p.D57N)

Variant ID: 1-115256542-C-T

NM_002524.4(NRAS):c.169G>A;(p.D57N)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Identification of NRAS Diagnostic Biomarkers and Drug Targets for Endometrial Cancer-An Integrated in Silico Approach.

International Journal Of Molecular Sciences
Alessandro, Larsen L; Low, Kat-Jun Eric KE; Abushelaibi, Aisha A; Lim, Swee-Hua Erin SE; Cheng, Wan-Hee WH; Chang, Sook-Keng SK; Lai, Kok-Song KS; Sum, Yap Wai YW; Maran, Sathiya S
Publication Date: 2022-11-18

Variant appearance in text: NRAS: D57N; rs1465850103
PubMed Link: 36430761
Variant Present in the following documents:
  • Main text
  • ijms-23-14285.pdf
View BVdb publication page



Computational Analysis of Deleterious SNPs in NRAS to Assess Their Potential Correlation With Carcinogenesis.

Frontiers In Genetics
Behairy, Mohammed Y MY; Soltan, Mohamed A MA; Adam, Mohamed S MS; Refaat, Ahmed M AM; Ezz, Ehab M EM; Albogami, Sarah S; Fayad, Eman E; Althobaiti, Fayez F; Gouda, Ahmed M AM; Sileem, Ashraf E AE; Elfaky, Mahmoud A MA; Darwish, Khaled M KM; Alaa Eldeen, Muhammad M
Publication Date: 2022

Variant appearance in text: NRAS: D57N; rs1465850103
PubMed Link: 36051694
Variant Present in the following documents:
  • Main text
  • fgene-13-872845.pdf
View BVdb publication page



Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports
Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA
Publication Date: 2020-09-21

Variant appearance in text: NRAS: D57N
PubMed Link: 32958805
Variant Present in the following documents:
  • 41598_2020_72404_MOESM2_ESM.xlsx, sheet 3
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: NRAS: D57N
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.

Molecular Cancer
Kovaleva, Valentina V; Geissler, Anna-Lena AL; Lutz, Lisa L; Fritsch, Ralph R; Makowiec, Frank F; Wiesemann, Sebastian S; Hopt, Ulrich T UT; Passlick, Bernward B; Werner, Martin M; Lassmann, Silke S
Publication Date: 2016-10-18

Variant appearance in text: NRAS: 169G>A; Asp57Asn
PubMed Link: 27756406
Variant Present in the following documents:
  • 12943_2016_549_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Compound EGFR mutation is frequently detected with co-mutations of actionable genes and associated with poor clinical outcome in lung adenocarcinoma.

Cancer Biology & Therapy
Kim, Eun Young EY; Cho, Eun Na EN; Park, Heae Surng HS; Hong, Ji Young JY; Lim, Seri S; Youn, Jong Pil JP; Hwang, Seung Yong SY; Chang, Yoon Soo YS
Publication Date: 2016

Variant appearance in text: NRAS: 169G>A
PubMed Link: 26785607
Variant Present in the following documents:
  • Main text
View BVdb publication page



Assessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients.

British Journal Of Cancer
Wong, S Q SQ; Fellowes, A A; Doig, K K; Ellul, J J; Bosma, T J TJ; Irwin, D D; Vedururu, R R; Tan, A Y-C AY; Weiss, J J; Chan, K S KS; Lucas, M M; Thomas, D M DM; Dobrovic, A A; Parisot, J P JP; Fox, S B SB
Publication Date: 2015-04-14

Variant appearance in text: NRAS: 169G>A; Asp57Asn
PubMed Link: 25742471
Variant Present in the following documents:
  • bjc201580x7.xls, sheet 1
View BVdb publication page