Publications:

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Phase Ib/II Trial of BRAF and EGFR inhibition in BRAFV600E metastatic colorectal cancer and other cancers: EVICT (Erlotinib and Vemurafenib In Combination Trial).

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Tan, Lavinia L; Tran, Ben B; Tie, Jeanne J; Markman, Ben B; Ananda, Sumi S; Tebbutt, Niall C NC; Michael, Michael M; Link, Emma E; Wong, Stephen Q SQ; Chandrashekar, Sushma S; Guinto, Jerick J; Ritchie, David D; Koldej, Rachel R; Solomon, Benjamin J BJ; McArthur, Grant A GA; Hicks, Rodney J RJ; Gibbs, Peter P; Dawson, Sarah-Jane SJ; Desai, Jayesh J

Publication Date: 2023-01-13

Variant appearance in text: NRAS: G12N

PubMed Link: 36638198

Variant Present in the following documents:

• 1017.pdf

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Effects of NRAS Mutations on Leukemogenesis and Targeting of Children With Acute Lymphoblastic Leukemia.

Frontiers In Cell And Developmental Biology

Qian, Jiabi J; Li, Zifeng Z; Pei, Kunlin K; Li, Ziping Z; Li, Chunjie C; Yan, Muxia M; Qian, Maoxiang M; Song, Yuanbin Y; Zhang, Hui H; He, Yingyi Y

Publication Date: 2022

Variant appearance in text: NRAS: G12N

PubMed Link: 35211470

Variant Present in the following documents:

• Main text
• DataSheet2.xlsx, sheet 8

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Enhanced interpretation of 935 hotspot and non-hotspot RAS variants using evidence-based structural bioinformatics.

Computational And Structural Biotechnology Journal

Tripathi, Swarnendu S; Dsouza, Nikita R NR; Mathison, Angela J AJ; Leverence, Elise E; Urrutia, Raul R; Zimmermann, Michael T MT

Publication Date: 2022

Variant appearance in text: NRAS: G12N

PubMed Link: 34976316

Variant Present in the following documents:

• main.pdf

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NRAS Mutations May Be Involved in the Pathogenesis of Cutaneous Rosai Dorfman Disease: A Pilot Study.

Biology

Wu, Kuan-Jou KJ; Li, Shu-Hao SH; Liao, Jia-Bin JB; Chiou, Chien-Chun CC; Wu, Chieh-Shan CS; Chen, Chien-Chin CC

Publication Date: 2021-05-02

Variant appearance in text: NRAS: G12N

PubMed Link: 34063325

Variant Present in the following documents:

• Main text

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: NRAS: G12N

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

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Embryonic Expression of NrasG 12 D Leads to Embryonic Lethality and Cardiac Defects.

Frontiers In Cell And Developmental Biology

You, Xiaona X; Ryu, Myung-Jeom MJ; Cho, Eunjin E; Sang, Yanzhi Y; Damnernsawad, Alisa A; Zhou, Yun Y; Liu, Yangang Y; Zhang, Jing J; Lee, Youngsook Y

Publication Date: 2021

Variant appearance in text: NRAS: G12N

PubMed Link: 33681212

Variant Present in the following documents:

• Main text
• fcell-09-633661.pdf

View BVdb publication page

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Conjunctival Melanoma: Update on Genetics, Epigenetics and Targeted Molecular and Immune-Based Therapies.

Clinical Ophthalmology (Auckland, N.Z.)

Gkiala, Anastasia A; Palioura, Sotiria S

Publication Date: 2020

Variant appearance in text: NRAS: G12N

PubMed Link: 33116365

Variant Present in the following documents:

• Main text
• opth-14-3137.pdf

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Clinical validation of the next-generation sequencing-based Extended RAS Panel assay using metastatic colorectal cancer patient samples from the phase 3 PRIME study.

Journal Of Cancer Research And Clinical Oncology

Udar, Nitin N; Lofton-Day, Catherine C; Dong, Jun J; Vavrek, Darcy D; Jung, A Scott AS; Meier, Kristen K; Iyer, Anita A; Slaughter, Ryan R; Gutekunst, Karen K; Bach, Bruce A BA; Peeters, Marc M; Douillard, Jean-Yves JY

Publication Date: 2018-10

Variant appearance in text: NRAS: Gly12Asn

PubMed Link: 30019318

Variant Present in the following documents:

• 432_2018_2688_MOESM1_ESM.pdf

View BVdb publication page

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NF1 mutations in conjunctival melanoma.

British Journal Of Cancer

Scholz, S L SL; Cosgarea, I I; Süßkind, D D; Murali, R R; Möller, I I; Reis, H H; Leonardelli, S S; Schilling, B B; Schimming, T T; Hadaschik, E E; Franklin, C C; Paschen, A A; Sucker, A A; Steuhl, K P KP; Schadendorf, D D; Westekemper, H H; Griewank, K G KG

Publication Date: 2018-05

Variant appearance in text: NRAS: G12N

PubMed Link: 29559732

Variant Present in the following documents:

• Main text
• 41416_2018_Article_46.pdf

View BVdb publication page

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: NRAS: G12N

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

View BVdb publication page

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Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Genome Research

Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U

Publication Date: 2017-04

Variant appearance in text: NRAS: G12N

PubMed Link: 28179366

Variant Present in the following documents:

• supp_gr.213546.116_Supplemental_Table_S7.xlsx, sheet 1

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Genetic hierarchy and temporal variegation in the clonal history of acute myeloid leukaemia.

Nature Communications

Hirsch, Pierre P; Zhang, Yanyan Y; Tang, Ruoping R; Joulin, Virginie V; Boutroux, Hélène H; Pronier, Elodie E; Moatti, Hannah H; Flandrin, Pascale P; Marzac, Christophe C; Bories, Dominique D; Fava, Fanny F; Mokrani, Hayat H; Betems, Aline A; Lorre, Florence F; Favier, Rémi R; Féger, Frédéric F; Mohty, Mohamad M; Douay, Luc L; Legrand, Ollivier O; Bilhou-Nabera, Chrystèle C; Louache, Fawzia F; Delhommeau, François F

Publication Date: 2016-08-18

Variant appearance in text: NRAS: G12N

PubMed Link: 27534895

Variant Present in the following documents:

• ncomms12475-s2.xlsx, sheet 1

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Recurrent inactivating RASA2 mutations in melanoma.

Nature Genetics

Arafeh, Rand R; Qutob, Nouar N; Emmanuel, Rafi R; Keren-Paz, Alona A; Madore, Jason J; Elkahloun, Abdel A; Wilmott, James S JS; Gartner, Jared J JJ; Di Pizio, Antonella A; Winograd-Katz, Sabina S; Sindiri, Sivasish S; Rotkopf, Ron R; Dutton-Regester, Ken K; Johansson, Peter P; Pritchard, Antonia L AL; Waddell, Nicola N; Hill, Victoria K VK; Lin, Jimmy C JC; Hevroni, Yael Y; Rosenberg, Steven A SA; Khan, Javed J; Ben-Dor, Shifra S; Niv, Masha Y MY; Ulitsky, Igor I; Mann, Graham J GJ; Scolyer, Richard A RA; Hayward, Nicholas K NK; Samuels, Yardena Y

Publication Date: 2015-12

Variant appearance in text: NRAS: G12N

PubMed Link: 26502337

Variant Present in the following documents:

• NIHMS65345-supplement-Supplementary_table_3.xlsx, sheet 2

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Ductal activation of oncogenic KRAS alone induces sarcomatoid phenotype.

Scientific Reports

Fu, Yong Y; Cruz-Monserrate, Zobeida Z; Helen Lin, H H; Chung, Yiyin Y; Ji, Baoan B; Lin, Szu-Min SM; Vonderfecht, Steven S; Logsdon, Craig D CD; Li, Chien-Feng CF; Ann, David K DK

Publication Date: 2015-08-20

Variant appearance in text: NRAS: G12N

PubMed Link: 26289340

Variant Present in the following documents:

• srep13347-s1.pdf

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Clinical Grade "SNaPshot" Genetic Mutation Profiling in Multiple Myeloma.

Ebiomedicine

O'Donnell, Elizabeth E; Mahindra, Anuj A; Yee, Andrew J AJ; Nardi, Valentina V; Birrer, Nicole N; Horick, Nora N; Borger, Darrell D; Finkelstein, Dianne D; Iafrate, John A JA; Raje, Noopur N

Publication Date: 2015-01

Variant appearance in text: NRAS: G12N

PubMed Link: 26137536

Variant Present in the following documents:

• Main text

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Cutaneous epithelial tumors induced by vemurafenib involve the MAPK and Pi3KCA pathways but not HPV nor HPyV viral infection.

Plos One

Frouin, Eric E; Guillot, Bernard B; Larrieux, Marion M; Tempier, Ariane A; Boulle, Nathalie N; Foulongne, Vincent V; Girard, Céline C; Costes, Valérie V; Solassol, Jérome J

Publication Date: 2014

Variant appearance in text: NRAS: G12N

PubMed Link: 25360634

Variant Present in the following documents:

• pone.0110478.pdf

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A highly recurrent RPS27 5'UTR mutation in melanoma.

Oncotarget

Dutton-Regester, Ken K; Gartner, Jared J JJ; Emmanuel, Rafi R; Qutob, Nouar N; Davies, Michael A MA; Gershenwald, Jeffrey E JE; Robinson, William W; Robinson, Steven S; Rosenberg, Steven A SA; Scolyer, Richard A RA; Mann, Graham J GJ; Thompson, John F JF; Hayward, Nicholas K NK; Samuels, Yardena Y

Publication Date: 2014-05-30

Variant appearance in text: NRAS: G12N

PubMed Link: 24913145

Variant Present in the following documents:

• oncotarget-05-2912-s003.xlsx, sheet 1

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Development and validation of a clinical trial patient stratification assay that interrogates 27 mutation sites in MAPK pathway genes.

Plos One

Chang, Ken C N KC; Galuska, Stefan S; Weiner, Russell R; Marton, Matthew J MJ

Publication Date: 2013

Variant appearance in text: NRAS: G12N

PubMed Link: 23991070

Variant Present in the following documents:

• Main text
• pone.0072239.pdf

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