Publications:

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Fueling genome maintenance: On the versatile roles of NAD+ in preserving DNA integrity.

The Journal Of Biological Chemistry

Ruszkiewicz, Joanna A JA; Bürkle, Alexander A; Mangerich, Aswin A

Publication Date: 2022-06

Variant appearance in text: PARP1: D993A

PubMed Link: 35595095

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Why structure and chain length matter: on the biological significance underlying the structural heterogeneity of poly(ADP-ribose).

Nucleic Acids Research

Reber, Julia M JM; Mangerich, Aswin A

Publication Date: 2021-09-07

Variant appearance in text: PARP: D993A

PubMed Link: 34302489

Variant Present in the following documents:

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• gkab618.pdf

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PARP1 catalytic variants reveal branching and chain length-specific functions of poly(ADP-ribose) in cellular physiology and stress response.

Nucleic Acids Research

Aberle, Lisa L; Krüger, Annika A; Reber, Julia M JM; Lippmann, Michelle M; Hufnagel, Matthias M; Schmalz, Michael M; Trussina, Irmela R E A IREA; Schlesiger, Sarah S; Zubel, Tabea T; Schütz, Karina K; Marx, Andreas A; Hartwig, Andrea A; Ferrando-May, Elisa E; Bürkle, Alexander A; Mangerich, Aswin A

Publication Date: 2020-10-09

Variant appearance in text: PARP1: D993A

PubMed Link: 32667640

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• Main text
• gkaa590.pdf

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The Enigmatic Function of PARP1: From PARylation Activity to PAR Readers.

Cells

Kamaletdinova, Tatiana T; Fanaei-Kahrani, Zahra Z; Wang, Zhao-Qi ZQ

Publication Date: 2019-12-12

Variant appearance in text: PARP1: D993A

PubMed Link: 31842403

Variant Present in the following documents:

• Main text
• cells-08-01625.pdf

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Kinetics of poly(ADP-ribosyl)ation, but not PARP1 itself, determines the cell fate in response to DNA damage in vitro and in vivo.

Nucleic Acids Research

Schuhwerk, Harald H; Bruhn, Christopher C; Siniuk, Kanstantsin K; Min, Wookee W; Erener, Suheda S; Grigaravicius, Paulius P; Krüger, Annika A; Ferrari, Elena E; Zubel, Tabea T; Lazaro, David D; Monajembashi, Shamci S; Kiesow, Kirstin K; Kroll, Torsten T; Bürkle, Alexander A; Mangerich, Aswin A; Hottiger, Michael M; Wang, Zhao-Qi ZQ

Publication Date: 2017-11-02

Variant appearance in text: PARP1: D993A

PubMed Link: 28977496

Variant Present in the following documents:

• Main text
• gkx717_supp.pdf
• gkx717.pdf

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Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer.

Nature Communications

Hao, Yujun Y; Samuels, Yardena Y; Li, Qingling Q; Krokowski, Dawid D; Guan, Bo-Jhih BJ; Wang, Chao C; Jin, Zhicheng Z; Dong, Bohan B; Cao, Bo B; Feng, Xiujing X; Xiang, Min M; Xu, Claire C; Fink, Stephen S; Meropol, Neal J NJ; Xu, Yan Y; Conlon, Ronald A RA; Markowitz, Sanford S; Kinzler, Kenneth W KW; Velculescu, Victor E VE; Brunengraber, Henri H; Willis, Joseph E JE; LaFramboise, Thomas T; Hatzoglou, Maria M; Zhang, Guo-Fang GF; Vogelstein, Bert B; Wang, Zhenghe Z

Publication Date: 2016-06-20

Variant appearance in text: PARP: D993A

PubMed Link: 27321283

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