PARP1 c.2633_2634delinsAT ;(p.R878H)

Variant ID: 1-226552727-CC-AT

NM_001618.3(PARP1):c.2633_2634delinsAT;(p.R878H)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


DNMT3A R882H mutation drives daunorubicin resistance in acute myeloid leukemia via regulating NRF2/NQO1 pathway.

Cell Communication And Signaling : Ccs
Chu, Xuan X; Zhong, Liang L; Dan, Wenran W; Wang, Xiao X; Zhang, Zhonghui Z; Liu, Zhenyan Z; Lu, Yang Y; Shao, Xin X; Zhou, Ziwei Z; Chen, Shuyu S; Liu, Beizhong B
Publication Date: 2022-10-27

Variant appearance in text: PARP: R878H
PubMed Link: 36303144
Variant Present in the following documents:
  • Main text
  • 12964_2022_Article_978.pdf
View BVdb publication page



Molecular Pathways in Clonal Hematopoiesis: From the Acquisition of Somatic Mutations to Transformation into Hematologic Neoplasm.

Life (Basel, Switzerland)
Gaulin, Charles C; Kelemen, Katalin K; Arana Yi, Cecilia C
Publication Date: 2022-07-28

Variant appearance in text: PARP: R878H
PubMed Link: 36013314
Variant Present in the following documents:
  • life-12-01135.pdf
View BVdb publication page



DNMT3A Harboring Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Venugopal, Kartika K; Feng, Yang Y; Nowialis, Pawel P; Xu, Huanzhou H; Shabashvili, Daniil E DE; Berntsen, Cassandra M CM; Kaur, Prabhjot P; Krajcik, Kathryn I KI; Taragjini, Christina C; Zaroogian, Zachary Z; Casellas Román, Heidi L HL; Posada, Luisa M LM; Gunaratne, Chamara C; Li, Jianping J; Dupéré-Richer, Daphné D; Bennett, Richard L RL; Pondugula, Santhi S; Riva, Alberto A; Cogle, Christopher R CR; Opavsky, Rene R; Law, Brian K BK; Bhaduri-McIntosh, Sumita S; Kubicek, Stefan S; Staber, Philipp B PB; Licht, Jonathan D JD; Bird, Jonathan E JE; Guryanova, Olga A OA
Publication Date: 2022-02-15

Variant appearance in text: PARP: R878H
PubMed Link: 34716195
Variant Present in the following documents:
  • Main text
  • ccr-21-2863_supp.pdf
  • 756.pdf
View BVdb publication page



Clonal hematopoiesis and associated diseases: A review of recent findings.

Cancer Science
Asada, Shuhei S; Kitamura, Toshio T
Publication Date: 2021-10

Variant appearance in text: PARP1: R878H
PubMed Link: 34328684
Variant Present in the following documents:
  • Main text
  • CAS-112-3962.pdf
View BVdb publication page



Novel single-cell technologies in acute myeloid leukemia research.

Translational Research : The Journal Of Laboratory And Clinical Medicine
Gupta, Soumyasri Das SD; Sachs, Zohar Z
Publication Date: 2017-11

Variant appearance in text: PARP: R878H
PubMed Link: 28802867
Variant Present in the following documents:
  • Main text
View BVdb publication page



DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling.

Nature Medicine
Guryanova, Olga A OA; Shank, Kaitlyn K; Spitzer, Barbara B; Luciani, Luisa L; Koche, Richard P RP; Garrett-Bakelman, Francine E FE; Ganzel, Chezi C; Durham, Benjamin H BH; Mohanty, Abhinita A; Hoermann, Gregor G; Rivera, Sharon A SA; Chramiec, Alan G AG; Pronier, Elodie E; Bastian, Lennart L; Keller, Matthew D MD; Tovbin, Daniel D; Loizou, Evangelia E; Weinstein, Abby R AR; Gonzalez, Adriana Rodriguez AR; Lieu, Yen K YK; Rowe, Jacob M JM; Pastore, Friederike F; McKenney, Anna Sophia AS; Krivtsov, Andrei V AV; Sperr, Wolfgang R WR; Cross, Justin R JR; Mason, Christopher E CE; Tallman, Martin S MS; Arcila, Maria E ME; Abdel-Wahab, Omar O; Armstrong, Scott A SA; Kubicek, Stefan S; Staber, Philipp B PB; Gönen, Mithat M; Paietta, Elisabeth M EM; Melnick, Ari M AM; Nimer, Stephen D SD; Mukherjee, Siddhartha S; Levine, Ross L RL
Publication Date: 2016-12

Variant appearance in text: PARP: R878H
PubMed Link: 27841873
Variant Present in the following documents:
  • Main text
View BVdb publication page