PARP1 c.1160A>C ;(p.D387A)

Variant ID: 1-226568909-T-G

NM_001618.3(PARP1):c.1160A>C;(p.D387A)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner.

Cell Cycle (Georgetown, Tex.)
Xu, Zhu Z; Zhang, Lei L; Zhang, Wenjun W; Meng, Du D; Zhang, Hongxia H; Jiang, Ying Y; Xu, Xiaojun X; Van Meter, Michael M; Seluanov, Andrei A; Gorbunova, Vera V; Mao, Zhiyong Z
Publication Date: 2015

Variant appearance in text: PARP1: D387A
PubMed Link: 25607651
Variant Present in the following documents:
  • Main text
View BVdb publication page



Caspase-8 cleaves its substrates from the plasma membrane upon CD95-induced apoptosis.

Cell Death And Differentiation
Beaudouin, J J; Liesche, C C; Aschenbrenner, S S; Hörner, M M; Eils, R R
Publication Date: 2013-04

Variant appearance in text: PARP: D387A
PubMed Link: 23306557
Variant Present in the following documents:
  • Main text
View BVdb publication page



SIRT6 promotes DNA repair under stress by activating PARP1.

Science (New York, N.Y.)
Mao, Zhiyong Z; Hine, Christopher C; Tian, Xiao X; Van Meter, Michael M; Au, Matthew M; Vaidya, Amita A; Seluanov, Andrei A; Gorbunova, Vera V
Publication Date: 2011-06-17

Variant appearance in text: PARP1: D387A
PubMed Link: 21680843
Variant Present in the following documents:
  • Main text
View BVdb publication page