PARP1 c.640G>A ;(p.D214N)

Variant ID: 1-226576434-C-T

NM_001618.3(PARP1):c.640G>A;(p.D214N)

This variant was identified in 13 publications

View GRCh38 version.




Publications:


Role of histone modification in the occurrence and development of osteoporosis.

Frontiers In Endocrinology
Sun, Pan P; Huang, Tingrui T; Huang, Chen C; Wang, Yongjun Y; Tang, Dezhi D
Publication Date: 2022

Variant appearance in text: PARP1: D214N
PubMed Link: 36093077
Variant Present in the following documents:
  • Main text
  • fendo-13-964103.pdf
View BVdb publication page



Truncated PARP1 mediates ADP-ribosylation of RNA polymerase III for apoptosis.

Cell Discovery
Chen, Qian Q; Ma, Kai K; Liu, Xiuhua X; Chen, Shih-Hsun SH; Li, Peng P; Yu, Yonghao Y; Leung, Anthony K L AKL; Yu, Xiaochun X
Publication Date: 2022-01-18

Variant appearance in text: PARP1: D214N
PubMed Link: 35039483
Variant Present in the following documents:
  • Main text
  • 41421_2021_Article_355.pdf
  • 41421_2021_355_MOESM1_ESM.pdf
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Truncated PARP1 mediates ADP-ribosylation of RNA polymerase III for apoptosis.

Cell Discovery
Chen, Qian Q; Ma, Kai K; Liu, Xiuhua X; Chen, Shih-Hsun SH; Li, Peng P; Yu, Yonghao Y; Leung, Anthony K L AKL; Yu, Xiaochun X
Publication Date: 2022-01-18

Variant appearance in text: PARP1: D214N
PubMed Link: 35039483
Variant Present in the following documents:
  • Main text
  • 41421_2021_Article_355.pdf
  • 41421_2021_355_MOESM1_ESM.pdf
View BVdb publication page



SPINDOC binds PARP1 to facilitate PARylation.

Nature Communications
Yang, Fen F; Chen, Jianji J; Liu, Bin B; Gao, Guozhen G; Sebastian, Manu M; Jeter, Collene C; Shen, Jianjun J; Person, Maria D MD; Bedford, Mark T MT
Publication Date: 2021-11-04

Variant appearance in text: PARP1: D214N
PubMed Link: 34737271
Variant Present in the following documents:
  • Main text
  • 41467_2021_Article_26588.pdf
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The Role of NLRP3 Inflammasome Activities in Bone Diseases and Vascular Calcification.

Inflammation
Yu, Chenyang C; Zhang, Caihua C; Kuang, Zhihui Z; Zheng, Qiang Q
Publication Date: 2021-04

Variant appearance in text: ARTD1: D214N
PubMed Link: 33215255
Variant Present in the following documents:
  • Main text
  • 10753_2020_Article_1357.pdf
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The Enigmatic Function of PARP1: From PARylation Activity to PAR Readers.

Cells
Kamaletdinova, Tatiana T; Fanaei-Kahrani, Zahra Z; Wang, Zhao-Qi ZQ
Publication Date: 2019-12-12

Variant appearance in text: PARP1: D214N
PubMed Link: 31842403
Variant Present in the following documents:
  • Main text
  • cells-08-01625.pdf
View BVdb publication page



PARP1 Hinders Histone H2B Occupancy at the NFATc1 Promoter to Restrain Osteoclast Differentiation.

Journal Of Bone And Mineral Research : The Official Journal Of The American Society For Bone And Mineral Research
Wang, Chun C; Xiao, Jianqiu J; Nowak, Kathrin K; Gunasekera, Kapila K; Alippe, Yael Y; Speckman, Sheree S; Yang, Tong T; Kress, Dustin D; Abu-Amer, Yousef Y; Hottiger, Michael O MO; Mbalaviele, Gabriel G
Publication Date: 2020-04

Variant appearance in text: PARP1: D214N
PubMed Link: 31793068
Variant Present in the following documents:
  • Main text
View BVdb publication page



Chronic inflammation triggered by the NLRP3 inflammasome in myeloid cells promotes growth plate dysplasia by mesenchymal cells.

Scientific Reports
Wang, Chun C; Xu, Can-Xin CX; Alippe, Yael Y; Qu, Chao C; Xiao, Jianqiu J; Schipani, Ernestina E; Civitelli, Roberto R; Abu-Amer, Yousef Y; Mbalaviele, Gabriel G
Publication Date: 2017-07-07

Variant appearance in text: PARP1: D214N
PubMed Link: 28687790
Variant Present in the following documents:
  • Main text
  • 41598_2017_Article_5033.pdf
  • 41598_2017_5033_MOESM1_ESM.pdf
View BVdb publication page



Epigenetic regulation of nitric oxide synthase 2, inducible (Nos2) by NLRC4 inflammasomes involves PARP1 cleavage.

Scientific Reports
Buzzo, Carina de Lima CL; Medina, Tiago T; Branco, Laura M LM; Lage, Silvia L SL; Ferreira, Luís Carlos de Souza LC; Amarante-Mendes, Gustavo P GP; Hottiger, Michael O MO; De Carvalho, Daniel D DD; Bortoluci, Karina R KR
Publication Date: 2017-02-02

Variant appearance in text: PARP1: D214N
PubMed Link: 28150715
Variant Present in the following documents:
  • Main text
  • srep41686.pdf
View BVdb publication page



Poly-ADP-ribosylation-mediated degradation of ARTD1 by the NLRP3 inflammasome is a prerequisite for osteoclast maturation.

Cell Death & Disease
Wang, C C; Qu, C C; Alippe, Y Y; Bonar, S L SL; Civitelli, R R; Abu-Amer, Y Y; Hottiger, M O MO; Mbalaviele, G G
Publication Date: 2016-03-24

Variant appearance in text: ARTD1: D214N
PubMed Link: 27010854
Variant Present in the following documents:
  • Main text
  • cddis201658x1.pdf
  • cddis201658a.pdf
View BVdb publication page



NLRP3 mediates osteolysis through inflammation-dependent and -independent mechanisms.

Faseb Journal : Official Publication Of The Federation Of American Societies For Experimental Biology
Qu, Chao C; Bonar, Sheri L SL; Hickman-Brecks, Cynthia L CL; Abu-Amer, Samer S; McGeough, Matthew D MD; Peña, Carla A CA; Broderick, Lori L; Yang, Chang C; Grimston, Susan K SK; Kading, Jacqueline J; Abu-Amer, Yousef Y; Novack, Deborah V DV; Hoffman, Hal M HM; Civitelli, Roberto R; Mbalaviele, Gabriel G
Publication Date: 2015-04

Variant appearance in text: PARP1: D214N
PubMed Link: 25477279
Variant Present in the following documents:
  • Main text
View BVdb publication page



Emerging Concepts about NAIP/NLRC4 Inflammasomes.

Frontiers In Immunology
Lage, Silvia Lucena SL; Longo, Carla C; Branco, Laura Migliari LM; da Costa, Thaís Boccia TB; Buzzo, Carina de Lima Cde L; Bortoluci, Karina Ramalho KR
Publication Date: 2014

Variant appearance in text: PARP1: D214N
PubMed Link: 25071770
Variant Present in the following documents:
  • Main text
  • fimmu-05-00309.pdf
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NLRP3 controls Trypanosoma cruzi infection through a caspase-1-dependent IL-1R-independent NO production.

Plos Neglected Tropical Diseases
Gonçalves, Virginia M VM; Matteucci, Kely C KC; Buzzo, Carina L CL; Miollo, Bruna H BH; Ferrante, Danny D; Torrecilhas, Ana C AC; Rodrigues, Mauricio M MM; Alvarez, Jose M JM; Bortoluci, Karina R KR
Publication Date: 2013

Variant appearance in text: PARP1: D214N
PubMed Link: 24098823
Variant Present in the following documents:
  • Main text
View BVdb publication page



Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling.

Molecular Biology Of The Cell
Los, Marek M; Mozoluk, Malgorzata M; Ferrari, Davide D; Stepczynska, Anna A; Stroh, Christopher C; Renz, Andrea A; Herceg, Zdenko Z; Wang, Zhao-Qi ZQ; Schulze-Osthoff, Klaus K
Publication Date: 2002-03

Variant appearance in text: PARP: D214N
PubMed Link: 11907276
Variant Present in the following documents:
  • Main text
View BVdb publication page