KCNK1 c.436_437delinsGA ;(p.L146D)

Variant ID: 1-233802421-CT-GA

NM_002245.3(KCNK1):c.436_437delinsGA;(p.L146D)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Structure/Activity Analysis of TASK-3 Channel Antagonists Based on a 5,6,7,8 tetrahydropyrido[4,3-d]pyrimidine.

International Journal Of Molecular Sciences
Ramírez, David D; Bedoya, Mauricio M; Kiper, Aytug K AK; Rinné, Susanne S; Morales-Navarro, Samuel S; Hernández-Rodríguez, Erix W EW; Sepúlveda, Francisco V FV; Decher, Niels N; González, Wendy W
Publication Date: 2019-05-07

Variant appearance in text: TWIK-1: L146D
PubMed Link: 31067753
Variant Present in the following documents:
  • Main text
  • ijms-20-02252.pdf
View BVdb publication page



Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels.

Nature Communications
Zheng, Wang W; Yang, Xiaoyong X; Hu, Ruikun R; Cai, Ruiqi R; Hofmann, Laura L; Wang, Zhifei Z; Hu, Qiaolin Q; Liu, Xiong X; Bulkley, David D; Yu, Yong Y; Tang, Jingfeng J; Flockerzi, Veit V; Cao, Ying Y; Cao, Erhu E; Chen, Xing-Zhen XZ
Publication Date: 2018-06-13

Variant appearance in text: TWIK-1: L146D
PubMed Link: 29899465
Variant Present in the following documents:
  • 41467_2018_4586_MOESM2_ESM.pdf
View BVdb publication page



A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel.

Nature Communications
Aryal, Prafulla P; Abd-Wahab, Firdaus F; Bucci, Giovanna G; Sansom, Mark S P MS; Tucker, Stephen J SJ
Publication Date: 2014-07-08

Variant appearance in text: TWIK-1: L146D
PubMed Link: 25001086
Variant Present in the following documents:
  • Main text
  • ncomms5377-s1.pdf
  • ncomms5377.pdf
View BVdb publication page