NR0B2 c.163A>G ;(p.T55A)

Variant ID: 1-27240269-T-C

NM_021969.2(NR0B2):c.163A>G;(p.T55A)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Feeding activates FGF15-SHP-TFEB-mediated lipophagy in the gut.

The Embo Journal
Seok, Sunmi S; Kim, Young-Chae YC; Zhang, Yang Y; Kong, Bo B; Guo, Grace G; Ma, Jian J; Kemper, Byron B; Kemper, Jongsook Kim JK
Publication Date: 2022-09-01

Variant appearance in text: SHP: T55A
PubMed Link: 35686465
Variant Present in the following documents:
  • EMBJ-41-e109997-s002.pdf
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Intestinal FGF15/19 physiologically repress hepatic lipogenesis in the late fed-state by activating SHP and DNMT3A.

Nature Communications
Kim, Young-Chae YC; Seok, Sunmi S; Zhang, Yang Y; Ma, Jian J; Kong, Bo B; Guo, Grace G; Kemper, Byron B; Kemper, Jongsook Kim JK
Publication Date: 2020-11-24

Variant appearance in text: SHP: T55A
PubMed Link: 33235221
Variant Present in the following documents:
  • Main text
  • 41467_2020_Article_19803.pdf
  • 41467_2020_19803_MOESM1_ESM.pdf
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Small Heterodimer Partner and Fibroblast Growth Factor 19 Inhibit Expression of NPC1L1 in Mouse Intestine and Cholesterol Absorption.

Gastroenterology
Kim, Young-Chae YC; Byun, Sangwon S; Seok, Sunmi S; Guo, Grace G; Xu, H Eric HE; Kemper, Byron B; Kemper, Jongsook Kim JK
Publication Date: 2019-03

Variant appearance in text: SHP: T55A
PubMed Link: 30521806
Variant Present in the following documents:
  • Main text
View BVdb publication page



AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle.

Nature Communications
Kim, Young-Chae YC; Seok, Sunmi S; Byun, Sangwon S; Kong, Bo B; Zhang, Yang Y; Guo, Grace G; Xie, Wen W; Ma, Jian J; Kemper, Byron B; Kemper, Jongsook Kim JK
Publication Date: 2018-02-07

Variant appearance in text: SHP: T55A
PubMed Link: 29416063
Variant Present in the following documents:
  • Main text
  • 41467_2018_Article_3060.pdf
  • 41467_2018_3060_MOESM2_ESM.pdf
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Liver ChIP-seq analysis in FGF19-treated mice reveals SHP as a global transcriptional partner of SREBP-2.

Genome Biology
Kim, Young-Chae YC; Byun, Sangwon S; Zhang, Yang Y; Seok, Sunmi S; Kemper, Byron B; Ma, Jian J; Kemper, Jongsook Kim JK
Publication Date: 2015-12-04

Variant appearance in text: SHP: T55A
PubMed Link: 26634251
Variant Present in the following documents:
  • Main text
  • 13059_2015_Article_835.pdf
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Bile acid signal-induced phosphorylation of small heterodimer partner by protein kinase Cζ is critical for epigenomic regulation of liver metabolic genes.

The Journal Of Biological Chemistry
Seok, Sunmi S; Kanamaluru, Deepthi D; Xiao, Zhen Z; Ryerson, Daniel D; Choi, Sung-E SE; Suino-Powell, Kelly K; Xu, H Eric HE; Veenstra, Timothy D TD; Kemper, Jongsook Kim JK
Publication Date: 2013-08-09

Variant appearance in text: SHP: T55A
PubMed Link: 23824184
Variant Present in the following documents:
  • Main text
View BVdb publication page