Small heterodimer partner interacts with NLRP3 and negatively regulates activation of the NLRP3 inflammasome.
Nature Communications
Yang, Chul-Su CS; Kim, Jwa-Jin JJ; Kim, Tae Sung TS; Lee, Phil Young PY; Kim, Soo Yeon SY; Lee, Hye-Mi HM; Shin, Dong-Min DM; Nguyen, Loi T LT; Lee, Moo-Seung MS; Jin, Hyo Sun HS; Kim, Kwang-Kyu KK; Lee, Chul-Ho CH; Kim, Myung Hee MH; Park, Sung Goo SG; Kim, Jin-Man JM; Choi, Hueng-Sik HS; Jo, Eun-Kyeong EK
Bile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin-proteasomal degradation.
Genes & Development
Miao, Ji J; Xiao, Zhen Z; Kanamaluru, Deepthi D; Min, Gyesik G; Yau, Peter M PM; Veenstra, Timothy D TD; Ellis, Ewa E; Strom, Steve S; Suino-Powell, Kelly K; Xu, H Eric HE; Kemper, Jongsook Kim JK