Genome-wide and phenome-wide analysis of ideal cardiovascular health in the VA Million Veteran Program.
Plos One
Huang, Rose D L RDL; Nguyen, Xuan-Mai T XT; Peloso, Gina M GM; Trinder, Mark M; Posner, Daniel C DC; Aragam, Krishna G KG; Ho, Yuk-Lam YL; Lynch, Julie A JA; Damrauer, Scott M SM; Chang, Kyong-Mi KM; Tsao, Philip S PS; Natarajan, Pradeep P; Assimes, Themistocles T; Gaziano, J Michael JM; Djousse, Luc L; Cho, Kelly K; Wilson, Peter W F PWF; Huffman, Jennifer E JE; O'Donnell, Christopher J CJ; ,
Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease.
Nature Communications
Schmidt, Amand F AF; Hunt, Nicholas B NB; Gordillo-Marañón, Maria M; Charoen, Pimphen P; Drenos, Fotios F; Kivimaki, Mika M; Lawlor, Deborah A DA; Giambartolomei, Claudia C; Papacosta, Olia O; Chaturvedi, Nishi N; Bis, Joshua C JC; O'Donnell, Christopher J CJ; Wannamethee, Goya G; Wong, Andrew A; Price, Jackie F JF; Hughes, Alun D AD; Gaunt, Tom R TR; Franceschini, Nora N; Mook-Kanamori, Dennis O DO; Zwierzyna, Magdalena M; Sofat, Reecha R; Hingorani, Aroon D AD; Finan, Chris C
Variants of PCSK9 Gene Are Associated with Subclinical Atherosclerosis and Cardiometabolic Parameters in Mexicans. The GEA Project.
Diagnostics (Basel, Switzerland)
Zamarrón-Licona, Erasmo E; Rodríguez-Pérez, José Manuel JM; Posadas-Sánchez, Rosalinda R; Vargas-Alarcón, Gilberto G; Baños-González, Manuel Alfonso MA; Borgonio-Cuadra, Verónica Marusa VM; Pérez-Hernández, Nonanzit N
Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study.
Plos Genetics
Gormley, Mark M; Yarmolinsky, James J; Dudding, Tom T; Burrows, Kimberley K; Martin, Richard M RM; Thomas, Steven S; Tyrrell, Jessica J; Brennan, Paul P; Pring, Miranda M; Boccia, Stefania S; Olshan, Andrew F AF; Diergaarde, Brenda B; Hung, Rayjean J RJ; Liu, Geoffrey G; Legge, Danny D; Tajara, Eloiza H EH; Severino, Patricia P; Lacko, Martin M; Ness, Andrew R AR; Davey Smith, George G; Vincent, Emma E EE; Richmond, Rebecca C RC
Integrative Analysis of Transcriptome-Wide Association Study and mRNA Expression Profiles Identified Candidate Genes and Pathways Associated With Acute Myocardial Infarction.
Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power.
Nature Genetics
Atkinson, Elizabeth G EG; Maihofer, Adam X AX; Kanai, Masahiro M; Martin, Alicia R AR; Karczewski, Konrad J KJ; Santoro, Marcos L ML; Ulirsch, Jacob C JC; Kamatani, Yoichiro Y; Okada, Yukinori Y; Finucane, Hilary K HK; Koenen, Karestan C KC; Nievergelt, Caroline M CM; Daly, Mark J MJ; Neale, Benjamin M BM
PCSK9 loss of function is protective against extra-coronary atherosclerotic cardiovascular disease in a large multi-ethnic cohort.
Plos One
Small, Aeron M AM; Huffman, Jennifer E JE; Klarin, Derek D; Lynch, Julie A JA; Assimes, Themistocles T; DuVall, Scott S; Sun, Yan V YV; Shere, Labiba L; Natarajan, Pradeep P; Gaziano, Michael M; Rader, Daniel J DJ; Wilson, Peter W F PWF; Tsao, Philip S PS; Chang, Kyong-Mi KM; Cho, Kelly K; O'Donnell, Christopher J CJ; Casas, Juan P JP; Damrauer, Scott M SM; ,
Depression and cardiovascular risk-association among Beck Depression Inventory, PCSK9 levels and insulin resistance.
Cardiovascular Diabetology
Macchi, C C; Favero, C C; Ceresa, A A; Vigna, L L; Conti, D M DM; Pesatori, A C AC; Racagni, G G; Corsini, A A; Ferri, N N; Sirtori, C R CR; Buoli, M M; Bollati, V V; Ruscica, M M
Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale.
Nature Genetics
Li, Xihao X; Li, Zilin Z; Zhou, Hufeng H; Gaynor, Sheila M SM; Liu, Yaowu Y; Chen, Han H; Sun, Ryan R; Dey, Rounak R; Arnett, Donna K DK; Aslibekyan, Stella S; Ballantyne, Christie M CM; Bielak, Lawrence F LF; Blangero, John J; Boerwinkle, Eric E; Bowden, Donald W DW; Broome, Jai G JG; Conomos, Matthew P MP; Correa, Adolfo A; Cupples, L Adrienne LA; Curran, Joanne E JE; Freedman, Barry I BI; Guo, Xiuqing X; Hindy, George G; Irvin, Marguerite R MR; Kardia, Sharon L R SLR; Kathiresan, Sekar S; Khan, Alyna T AT; Kooperberg, Charles L CL; Laurie, Cathy C CC; Liu, X Shirley XS; Mahaney, Michael C MC; Manichaikul, Ani W AW; Martin, Lisa W LW; Mathias, Rasika A RA; McGarvey, Stephen T ST; Mitchell, Braxton D BD; Montasser, May E ME; Moore, Jill E JE; Morrison, Alanna C AC; O'Connell, Jeffrey R JR; Palmer, Nicholette D ND; Pampana, Akhil A; Peralta, Juan M JM; Peyser, Patricia A PA; Psaty, Bruce M BM; Redline, Susan S; Rice, Kenneth M KM; Rich, Stephen S SS; Smith, Jennifer A JA; Tiwari, Hemant K HK; Tsai, Michael Y MY; Vasan, Ramachandran S RS; Wang, Fei Fei FF; Weeks, Daniel E DE; Weng, Zhiping Z; Wilson, James G JG; Yanek, Lisa R LR; , ; , ; Neale, Benjamin M BM; Sunyaev, Shamil R SR; Abecasis, Gonçalo R GR; Rotter, Jerome I JI; Willer, Cristen J CJ; Peloso, Gina M GM; Natarajan, Pradeep P; Lin, Xihong X
Characterization of Exome Variants and Their Metabolic Impact in 6,716 American Indians from the Southwest US.
American Journal Of Human Genetics
Kim, Hye In HI; Ye, Bin B; Gosalia, Nehal N; , ; Köroğlu, Çiğdem Ç; Hanson, Robert L RL; Hsueh, Wen-Chi WC; Knowler, William C WC; Baier, Leslie J LJ; Bogardus, Clifton C; Shuldiner, Alan R AR; Van Hout, Cristopher V CV
Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels.
Circulation. Genomic And Precision Medicine
Wang, Zhe Z; Chen, Han H; Bartz, Traci M TM; Bielak, Lawrence F LF; Chasman, Daniel I DI; Feitosa, Mary F MF; Franceschini, Nora N; Guo, Xiuqing X; Lim, Elise E; Noordam, Raymond R; Richard, Melissa A MA; Wang, Heming H; Cade, Brian B; Cupples, L Adrienne LA; de Vries, Paul S PS; Giulanini, Franco F; Lee, Jiwon J; Lemaitre, Rozenn N RN; Martin, Lisa W LW; Reiner, Alex P AP; Rich, Stephen S SS; Schreiner, Pamela J PJ; Sidney, Stephen S; Sitlani, Colleen M CM; Smith, Jennifer A JA; Willems van Dijk, Ko K; Yao, Jie J; Zhao, Wei W; Fornage, Myriam M; Kardia, Sharon L R SLR; Kooperberg, Charles C; Liu, Ching-Ti CT; Mook-Kanamori, Dennis O DO; Province, Michael A MA; Psaty, Bruce M BM; Redline, Susan S; Ridker, Paul M PM; Rotter, Jerome I JI; Boerwinkle, Eric E; Morrison, Alanna C AC; ,
Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer.
Jama
Yarmolinsky, James J; Bull, Caroline J CJ; Vincent, Emma E EE; Robinson, Jamie J; Walther, Axel A; Smith, George Davey GD; Lewis, Sarah J SJ; Relton, Caroline L CL; Martin, Richard M RM
Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.
Bmc Cardiovascular Disorders
Schmidt, Amand F AF; Holmes, Michael V MV; Preiss, David D; Swerdlow, Daniel I DI; Denaxas, Spiros S; Fatemifar, Ghazaleh G; Faraway, Rupert R; Finan, Chris C; Valentine, Dennis D; Fairhurst-Hunter, Zammy Z; Hartwig, Fernando Pires FP; Horta, Bernardo Lessa BL; Hypponen, Elina E; Power, Christine C; Moldovan, Max M; van Iperen, Erik E; Hovingh, Kees K; Demuth, Ilja I; Norman, Kristina K; Steinhagen-Thiessen, Elisabeth E; Demuth, Juri J; Bertram, Lars L; Lill, Christina M CM; Coassin, Stefan S; Willeit, Johann J; Kiechl, Stefan S; Willeit, Karin K; Mason, Dan D; Wright, John J; Morris, Richard R; Wanamethee, Goya G; Whincup, Peter P; Ben-Shlomo, Yoav Y; McLachlan, Stela S; Price, Jackie F JF; Kivimaki, Mika M; Welch, Catherine C; Sanchez-Galvez, Adelaida A; Marques-Vidal, Pedro P; Nicolaides, Andrew A; Panayiotou, Andrie G AG; Onland-Moret, N Charlotte NC; van der Schouw, Yvonne T YT; Matullo, Giuseppe G; Fiorito, Giovanni G; Guarrera, Simonetta S; Sacerdote, Carlotta C; Wareham, Nicholas J NJ; Langenberg, Claudia C; Scott, Robert A RA; Luan, Jian'an J; Bobak, Martin M; Malyutina, Sofia S; Pająk, Andrzej A; Kubinova, Ruzena R; Tamosiunas, Abdonas A; Pikhart, Hynek H; Grarup, Niels N; Pedersen, Oluf O; Hansen, Torben T; Linneberg, Allan A; Jess, Tine T; Cooper, Jackie J; Humphries, Steve E SE; Brilliant, Murray M; Kitchner, Terrie T; Hakonarson, Hakon H; Carrell, David S DS; McCarty, Catherine A CA; Lester, Kirchner H KH; Larson, Eric B EB; Crosslin, David R DR; de Andrade, Mariza M; Roden, Dan M DM; Denny, Joshua C JC; Carty, Cara C; Hancock, Stephen S; Attia, John J; Holliday, Elizabeth E; Scott, Rodney R; Schofield, Peter P; O'Donnell, Martin M; Yusuf, Salim S; Chong, Michael M; Pare, Guillaume G; van der Harst, Pim P; Said, M Abdullah MA; Eppinga, Ruben N RN; Verweij, Niek N; Snieder, Harold H; , ; Christen, Tim T; Mook-Kanamori, D O DO; , ; Gustafsson, Stefan S; Lind, Lars L; Ingelsson, Erik E; Pazoki, Raha R; Franco, Oscar O; Hofman, Albert A; Uitterlinden, Andre A; Dehghan, Abbas A; Teumer, Alexander A; Baumeister, Sebastian S; Dörr, Marcus M; Lerch, Markus M MM; Völker, Uwe U; Völzke, Henry H; Ward, Joey J; Pell, Jill P JP; Meade, Tom T; Christophersen, Ingrid E IE; Maitland-van der Zee, Anke H AH; Baranova, Ekaterina V EV; Young, Robin R; Ford, Ian I; Campbell, Archie A; Padmanabhan, Sandosh S; Bots, Michiel L ML; Grobbee, Diederick E DE; Froguel, Philippe P; Thuillier, Dorothée D; Roussel, Ronan R; Bonnefond, Amélie A; Cariou, Bertrand B; Smart, Melissa M; Bao, Yanchun Y; Kumari, Meena M; Mahajan, Anubha A; Hopewell, Jemma C JC; Seshadri, Sudha S; , ; Dale, Caroline C; Costa, Rui Providencia E RPE; Ridker, Paul M PM; Chasman, Daniel I DI; Reiner, Alex P AP; Ritchie, Marylyn D MD; Lange, Leslie A LA; Cornish, Alex J AJ; Dobbins, Sara E SE; Hemminki, Kari K; Kinnersley, Ben B; Sanson, Marc M; Labreche, Karim K; Simon, Matthias M; Bondy, Melissa M; Law, Philip P; Speedy, Helen H; Allan, James J; Li, Ni N; Went, Molly M; Weinhold, Niels N; Morgan, Gareth G; Sonneveld, Pieter P; Nilsson, Björn B; Goldschmidt, Hartmut H; Sud, Amit A; Engert, Andreas A; Hansson, Markus M; Hemingway, Harry H; Asselbergs, Folkert W FW; Patel, Riyaz S RS; Keating, Brendan J BJ; Sattar, Naveed N; Houlston, Richard R; Casas, Juan P JP; Hingorani, Aroon D AD
A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context.
Nature Communications
Gallois, Apolline A; Mefford, Joel J; Ko, Arthur A; Vaysse, Amaury A; Julienne, Hanna H; Ala-Korpela, Mika M; Laakso, Markku M; Zaitlen, Noah N; Pajukanta, Päivi P; Aschard, Hugues H
A Genetic Approach to the Association Between PCSK9 and Sepsis.
Jama Network Open
Feng, QiPing Q; Wei, Wei-Qi WQ; Chaugai, Sandip S; Carranza Leon, Barbara G BG; Kawai, Vivian V; Carranza Leon, Daniel A DA; Jiang, Lan L; Zhong, Xue X; Liu, Ge G; Ihegword, Andrea A; Shaffer, Christian M CM; Linton, MacRae F MF; Chung, Cecilia P CP; Stein, C Michael CM
Association of Triglyceride-Lowering LPL Variants and LDL-C-Lowering LDLR Variants With Risk of Coronary Heart Disease.
Jama
Ference, Brian A BA; Kastelein, John J P JJP; Ray, Kausik K KK; Ginsberg, Henry N HN; Chapman, M John MJ; Packard, Chris J CJ; Laufs, Ulrich U; Oliver-Williams, Clare C; Wood, Angela M AM; Butterworth, Adam S AS; Di Angelantonio, Emanuele E; Danesh, John J; Nicholls, Stephen J SJ; Bhatt, Deepak L DL; Sabatine, Marc S MS; Catapano, Alberico L AL
Multilocus Analysis of Genetic Susceptibility to Myocardial Infarction in Russians: Replication Study.
Acta Naturae
Kukava, N G NG; Titov, B V BV; Osmak, G J GJ; Matveeva, N A NA; Kulakova, O G OG; Favorov, A V AV; Shakhnovich, R M RM; Ruda, M Ya MY; Favorova, O O OO
Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
Genome Medicine
Nagy, Reka R; Boutin, Thibaud S TS; Marten, Jonathan J; Huffman, Jennifer E JE; Kerr, Shona M SM; Campbell, Archie A; Evenden, Louise L; Gibson, Jude J; Amador, Carmen C; Howard, David M DM; Navarro, Pau P; Morris, Andrew A; Deary, Ian J IJ; Hocking, Lynne J LJ; Padmanabhan, Sandosh S; Smith, Blair H BH; Joshi, Peter P; Wilson, James F JF; Hastie, Nicholas D ND; Wright, Alan F AF; McIntosh, Andrew M AM; Porteous, David J DJ; Haley, Chris S CS; Vitart, Veronique V; Hayward, Caroline C
The Relationship Between Coronary Artery Disease and Genetic Polymorphisms of Melanoma Inhibitory Activity 3.
Iranian Red Crescent Medical Journal
Zaimkohan, Hooshang H; Keramatipour, Mohammad M; Mirhafez, Seyed Reza SR; Tavakkoly-Bazzaz, Javad J; Tahooni, Azadeh A; Piryaei, Mohammad M; Ghayour-Mobarhan, Majid M; Ghaderian, Seyed Mohammad Hossein SM
PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.
The Lancet. Diabetes & Endocrinology
Schmidt, Amand F AF; Swerdlow, Daniel I DI; Holmes, Michael V MV; Patel, Riyaz S RS; Fairhurst-Hunter, Zammy Z; Lyall, Donald M DM; Hartwig, Fernando Pires FP; Horta, Bernardo Lessa BL; Hyppönen, Elina E; Power, Christine C; Moldovan, Max M; van Iperen, Erik E; Hovingh, G Kees GK; Demuth, Ilja I; Norman, Kristina K; Steinhagen-Thiessen, Elisabeth E; Demuth, Juri J; Bertram, Lars L; Liu, Tian T; Coassin, Stefan S; Willeit, Johann J; Kiechl, Stefan S; Willeit, Karin K; Mason, Dan D; Wright, John J; Morris, Richard R; Wanamethee, Goya G; Whincup, Peter P; Ben-Shlomo, Yoav Y; McLachlan, Stela S; Price, Jackie F JF; Kivimaki, Mika M; Welch, Catherine C; Sanchez-Galvez, Adelaida A; Marques-Vidal, Pedro P; Nicolaides, Andrew A; Panayiotou, Andrie G AG; Onland-Moret, N Charlotte NC; van der Schouw, Yvonne T YT; Matullo, Giuseppe G; Fiorito, Giovanni G; Guarrera, Simonetta S; Sacerdote, Carlotta C; Wareham, Nicholas J NJ; Langenberg, Claudia C; Scott, Robert R; Luan, Jian'an J; Bobak, Martin M; Malyutina, Sofia S; Pająk, Andrzej A; Kubinova, Ruzena R; Tamosiunas, Abdonas A; Pikhart, Hynek H; Husemoen, Lise Lotte Nystrup LL; Grarup, Niels N; Pedersen, Oluf O; Hansen, Torben T; Linneberg, Allan A; Simonsen, Kenneth Starup KS; Cooper, Jackie J; Humphries, Steve E SE; Brilliant, Murray M; Kitchner, Terrie T; Hakonarson, Hakon H; Carrell, David S DS; McCarty, Catherine A CA; Kirchner, H Lester HL; Larson, Eric B EB; Crosslin, David R DR; de Andrade, Mariza M; Roden, Dan M DM; Denny, Joshua C JC; Carty, Cara C; Hancock, Stephen S; Attia, John J; Holliday, Elizabeth E; O'Donnell, Martin M; Yusuf, Salim S; Chong, Michael M; Pare, Guillaume G; van der Harst, Pim P; Said, M Abdullah MA; Eppinga, Ruben N RN; Verweij, Niek N; Snieder, Harold H; , ; Christen, Tim T; Mook-Kanamori, Dennis O DO; Gustafsson, Stefan S; Lind, Lars L; Ingelsson, Erik E; Pazoki, Raha R; Franco, Oscar O; Hofman, Albert A; Uitterlinden, Andre A; Dehghan, Abbas A; Teumer, Alexander A; Baumeister, Sebastian S; Dörr, Marcus M; Lerch, Markus M MM; Völker, Uwe U; Völzke, Henry H; Ward, Joey J; Pell, Jill P JP; Smith, Daniel J DJ; Meade, Tom T; Maitland-van der Zee, Anke H AH; Baranova, Ekaterina V EV; Young, Robin R; Ford, Ian I; Campbell, Archie A; Padmanabhan, Sandosh S; Bots, Michiel L ML; Grobbee, Diederick E DE; Froguel, Philippe P; Thuillier, Dorothée D; Balkau, Beverley B; Bonnefond, Amélie A; Cariou, Bertrand B; Smart, Melissa M; Bao, Yanchun Y; Kumari, Meena M; Mahajan, Anubha A; Ridker, Paul M PM; Chasman, Daniel I DI; Reiner, Alex P AP; Lange, Leslie A LA; Ritchie, Marylyn D MD; Asselbergs, Folkert W FW; Casas, Juan-Pablo JP; Keating, Brendan J BJ; Preiss, David D; Hingorani, Aroon D AD; , ; Sattar, Naveed N
A 19-SNP coronary heart disease gene score profile in subjects with type 2 diabetes: the coronary heart disease risk in type 2 diabetes (CoRDia study) study baseline characteristics.
Cardiovascular Diabetology
Beaney, Katherine E KE; Ward, Claire E CE; Bappa, Dauda A S DA; McGale, Nadine N; Davies, Anna K AK; Hirani, Shashivadan P SP; Li, KaWah K; Howard, Philip P; Vance, Dwaine R DR; Crockard, Martin A MA; Lamont, John V JV; Newman, Stanton S; Humphries, Steve E SE
Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps.
Nature Genetics
Iotchkova, Valentina V; Huang, Jie J; Morris, John A JA; Jain, Deepti D; Barbieri, Caterina C; Walter, Klaudia K; Min, Josine L JL; Chen, Lu L; Astle, William W; Cocca, Massimilian M; Deelen, Patrick P; Elding, Heather H; Farmaki, Aliki-Eleni AE; Franklin, Christopher S CS; Franberg, Mattias M; Gaunt, Tom R TR; Hofman, Albert A; Jiang, Tao T; Kleber, Marcus E ME; Lachance, Genevieve G; Luan, Jian'an J; Malerba, Giovanni G; Matchan, Angela A; Mead, Daniel D; Memari, Yasin Y; Ntalla, Ioanna I; Panoutsopoulou, Kalliope K; Pazoki, Raha R; Perry, John R B JRB; Rivadeneira, Fernando F; Sabater-Lleal, Maria M; Sennblad, Bengt B; Shin, So-Youn SY; Southam, Lorraine L; Traglia, Michela M; van Dijk, Freerk F; van Leeuwen, Elisabeth M EM; Zaza, Gianluigi G; Zhang, Weihua W; , ; Amin, Najaf N; Butterworth, Adam A; Chambers, John C JC; Dedoussis, George G; Dehghan, Abbas A; Franco, Oscar H OH; Franke, Lude L; Frontini, Mattia M; Gambaro, Giovanni G; Gasparini, Paolo P; Hamsten, Anders A; Issacs, Aaron A; Kooner, Jaspal S JS; Kooperberg, Charles C; Langenberg, Claudia C; Marz, Winfried W; Scott, Robert A RA; Swertz, Morris A MA; Toniolo, Daniela D; Uitterlinden, Andre G AG; van Duijn, Cornelia M CM; Watkins, Hugh H; Zeggini, Eleftheria E; Maurano, Mathew T MT; Timpson, Nicholas J NJ; Reiner, Alexander P AP; Auer, Paul L PL; Soranzo, Nicole N
Analysis with the exome array identifies multiple new independent variants in lipid loci.
Human Molecular Genetics
Kanoni, Stavroula S; Masca, Nicholas G D NG; Stirrups, Kathleen E KE; Varga, Tibor V TV; Warren, Helen R HR; Scott, Robert A RA; Southam, Lorraine L; Zhang, Weihua W; Yaghootkar, Hanieh H; Müller-Nurasyid, Martina M; Couto Alves, Alexessander A; Strawbridge, Rona J RJ; Lataniotis, Lazaros L; An Hashim, Nikman N; Besse, Céline C; Boland, Anne A; Braund, Peter S PS; Connell, John M JM; Dominiczak, Anna A; Farmaki, Aliki-Eleni AE; Franks, Stephen S; Grallert, Harald H; Jansson, Jan-Håkan JH; Karaleftheri, Maria M; Keinänen-Kiukaanniemi, Sirkka S; Matchan, Angela A; Pasko, Dorota D; Peters, Annette A; Poulter, Neil N; Rayner, Nigel W NW; Renström, Frida F; Rolandsson, Olov O; Sabater-Lleal, Maria M; Sennblad, Bengt B; Sever, Peter P; Shields, Denis D; Silveira, Angela A; Stanton, Alice V AV; Strauch, Konstantin K; Tomaszewski, Maciej M; Tsafantakis, Emmanouil E; Waldenberger, Melanie M; Blakemore, Alexandra I F AI; Dedoussis, George G; Escher, Stefan A SA; Kooner, Jaspal S JS; McCarthy, Mark I MI; Palmer, Colin N A CN; , ; Hamsten, Anders A; Caulfield, Mark J MJ; Frayling, Timothy M TM; Tobin, Martin D MD; Jarvelin, Marjo-Riitta MR; Zeggini, Eleftheria E; Gieger, Christian C; Chambers, John C JC; Wareham, Nick J NJ; Munroe, Patricia B PB; Franks, Paul W PW; Samani, Nilesh J NJ; Deloukas, Panos P
Influence of Genetic Risk Factors on Coronary Heart Disease Occurrence in Afro-Caribbeans.
The Canadian Journal Of Cardiology
Larifla, Laurent L; Beaney, Katherine E KE; Foucan, Lydia L; Bangou, Jacqueline J; Michel, Carl T CT; Martino, Jean J; Velayoudom-Cephise, Fritz-Line FL; Cooper, Jackie A JA; Humphries, Steve E SE
Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program.
Atherosclerosis
Simino, Jeannette J; Kume, Rezart R; Kraja, Aldi T AT; Turner, Stephen T ST; Hanis, Craig L CL; Sheu, Wayne W; Chen, Ida I; Jaquish, Cashell C; Cooper, Richard S RS; Chakravarti, Aravinda A; Quertermous, Thomas T; Boerwinkle, Eric E; Hunt, Steven C SC; Rao, D C DC
Pharmacogenetics in cardiovascular disease: the challenge of moving from promise to realization: concepts discussed at the Canadian Network and Centre for Trials Internationally Network Conference (CANNeCTIN), June 2009.
Clinical Cardiology
Joseph, Philip G PG; Pare, Guillaume G; Ross, Stephanie S; Roberts, Robert R; Anand, Sonia S SS
No evidence of interaction between known lipid-associated genetic variants and smoking in the multi-ethnic PAGE population.
Human Genetics
Dumitrescu, Logan L; Carty, Cara L CL; Franceschini, Nora N; Hindorff, Lucia A LA; Cole, Shelley A SA; Bůžková, Petra P; Schumacher, Fredrick R FR; Eaton, Charles B CB; Goodloe, Robert J RJ; Duggan, David J DJ; Haessler, Jeff J; Cochran, Barbara B; Henderson, Brian E BE; Cheng, Iona I; Johnson, Karen C KC; Carlson, Chris S CS; Love, Shelly-Anne SA; Brown-Gentry, Kristin K; Nato, Alejandro Q AQ; Quibrera, Miguel M; Shohet, Ralph V RV; Ambite, José Luis JL; Wilkens, Lynne R LR; Le Marchand, Loïc L; Haiman, Christopher A CA; Buyske, Steven S; Kooperberg, Charles C; North, Kari E KE; Fornage, Myriam M; Crawford, Dana C DC
Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network.
Plos Genetics
Pendergrass, Sarah A SA; Brown-Gentry, Kristin K; Dudek, Scott S; Frase, Alex A; Torstenson, Eric S ES; Goodloe, Robert R; Ambite, Jose Luis JL; Avery, Christy L CL; Buyske, Steve S; Bůžková, Petra P; Deelman, Ewa E; Fesinmeyer, Megan D MD; Haiman, Christopher A CA; Heiss, Gerardo G; Hindorff, Lucia A LA; Hsu, Chu-Nan CN; Jackson, Rebecca D RD; Kooperberg, Charles C; Le Marchand, Loic L; Lin, Yi Y; Matise, Tara C TC; Monroe, Kristine R KR; Moreland, Larry L; Park, Sungshim L SL; Reiner, Alex A; Wallace, Robert R; Wilkens, Lynn R LR; Crawford, Dana C DC; Ritchie, Marylyn D MD
PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or noncardiovascular clinical events in an elderly population.
Journal Of Lipid Research
Postmus, Iris I; Trompet, Stella S; de Craen, Anton J M AJ; Buckley, Brendan M BM; Ford, Ian I; Stott, David J DJ; Sattar, Naveed N; Slagboom, P Eline PE; Westendorp, Rudi G J RG; Jukema, J Wouter JW
Polymorphisms in the fetal progesterone receptor and a calcium-activated potassium channel isoform are associated with preterm birth in an Argentinian population.
Journal Of Perinatology : Official Journal Of The California Perinatal Association
Mann, P C PC; Cooper, M E ME; Ryckman, K K KK; Comas, B B; Gili, J J; Crumley, S S; Bream, E N A EN; Byers, H M HM; Piester, T T; Schaefer, A A; Christine, P J PJ; Lawrence, A A; Schaa, K L KL; Kelsey, K J P KJ; Berends, S K SK; Momany, A M AM; Gadow, E E; Cosentino, V V; Castilla, E E EE; López Camelo, J J; Saleme, C C; Day, L J LJ; England, S K SK; Marazita, M L ML; Dagle, J M JM; Murray, J C JC
Investigation of genetic risk factors for chronic adult diseases for association with preterm birth.
Human Genetics
Falah, Nadia N; McElroy, Jude J; Snegovskikh, Victoria V; Lockwood, Charles J CJ; Norwitz, Errol E; Murray, Jeffey C JC; Kuczynski, Edward E; Menon, Ramkumar R; Teramo, Kari K; Muglia, Louis J LJ; Morgan, Thomas T
Prioritizing genetic variants for causality on the basis of preferential linkage disequilibrium.
American Journal Of Human Genetics
Zhu, Qianqian Q; Ge, Dongliang D; Heinzen, Erin L EL; Dickson, Samuel P SP; Urban, Thomas J TJ; Zhu, Mingfu M; Maia, Jessica M JM; He, Min M; Zhao, Qian Q; Shianna, Kevin V KV; Goldstein, David B DB
Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
Plos One
Musunuru, Kiran K; Romaine, Simon P R SP; Lettre, Guillaume G; Wilson, James G JG; Volcik, Kelly A KA; Tsai, Michael Y MY; Taylor, Herman A HA; Schreiner, Pamela J PJ; Rotter, Jerome I JI; Rich, Stephen S SS; Redline, Susan S; Psaty, Bruce M BM; Papanicolaou, George J GJ; Ordovas, Jose M JM; Liu, Kiang K; Krauss, Ronald M RM; Glazer, Nicole L NL; Gabriel, Stacey B SB; Fornage, Myriam M; Cupples, L Adrienne LA; Buxbaum, Sarah G SG; Boerwinkle, Eric E; Ballantyne, Christie M CM; Kathiresan, Sekar S; Rader, Daniel J DJ
Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a).
Journal Of Lipid Research
Deshmukh, Harshal A HA; Colhoun, Helen M HM; Johnson, Toby T; McKeigue, Paul M PM; Betteridge, D John DJ; Durrington, Paul N PN; Fuller, John H JH; Livingstone, Shona S; Charlton-Menys, Valentine V; Neil, Andrew A; Poulter, Neil N; Sever, Peter P; Shields, Denis C DC; Stanton, Alice V AV; Chatterjee, Aurobindo A; Hyde, Craig C; Calle, Roberto A RA; DeMicco, David A DA; Trompet, Stella S; Postmus, Iris I; Ford, Ian I; Jukema, J Wouter JW; Caulfield, Mark M; Hitman, Graham A GA
Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study.
Plos Genetics
Dumitrescu, Logan L; Carty, Cara L CL; Taylor, Kira K; Schumacher, Fredrick R FR; Hindorff, Lucia A LA; Ambite, José L JL; Anderson, Garnet G; Best, Lyle G LG; Brown-Gentry, Kristin K; Bůžková, Petra P; Carlson, Christopher S CS; Cochran, Barbara B; Cole, Shelley A SA; Devereux, Richard B RB; Duggan, Dave D; Eaton, Charles B CB; Fornage, Myriam M; Franceschini, Nora N; Haessler, Jeff J; Howard, Barbara V BV; Johnson, Karen C KC; Laston, Sandra S; Kolonel, Laurence N LN; Lee, Elisa T ET; MacCluer, Jean W JW; Manolio, Teri A TA; Pendergrass, Sarah A SA; Quibrera, Miguel M; Shohet, Ralph V RV; Wilkens, Lynne R LR; Haiman, Christopher A CA; Le Marchand, Loïc L; Buyske, Steven S; Kooperberg, Charles C; North, Kari E KE; Crawford, Dana C DC
Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.
European Journal Of Epidemiology
Janssens, A Cecile J W AC; Ioannidis, John P A JP; Bedrosian, Sara S; Boffetta, Paolo P; Dolan, Siobhan M SM; Dowling, Nicole N; Fortier, Isabel I; Freedman, Andrew N AN; Grimshaw, Jeremy M JM; Gulcher, Jeffrey J; Gwinn, Marta M; Hlatky, Mark A MA; Janes, Holly H; Kraft, Peter P; Melillo, Stephanie S; O'Donnell, Christopher J CJ; Pencina, Michael J MJ; Ransohoff, David D; Schully, Sheri D SD; Seminara, Daniela D; Winn, Deborah M DM; Wright, Caroline F CF; van Duijn, Cornelia M CM; Little, Julian J; Khoury, Muin J MJ
Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.
European Journal Of Human Genetics : Ejhg
Janssens, A Cecile J W AC; Ioannidis, John P A JP; Bedrosian, Sara S; Boffetta, Paolo P; Dolan, Siobhan M SM; Dowling, Nicole N; Fortier, Isabel I; Freedman, Andrew N AN; Grimshaw, Jeremy M JM; Gulcher, Jeffrey J; Gwinn, Marta M; Hlatky, Mark A MA; Janes, Holly H; Kraft, Peter P; Melillo, Stephanie S; O'Donnell, Christopher J CJ; Pencina, Michael J MJ; Ransohoff, David D; Schully, Sheri D SD; Seminara, Daniela D; Winn, Deborah M DM; Wright, Caroline F CF; van Duijn, Cornelia M CM; Little, Julian J; Khoury, Muin J MJ
Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.
Lipids In Health And Disease
Ronald, James J; Rajagopalan, Ramakrishnan R; Ranchalis, Jane E JE; Marshall, Julieann K JK; Hatsukami, Thomas S TS; Heagerty, Patrick J PJ; Jarvik, Gail P GP
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
American Journal Of Human Genetics
Talmud, Philippa J PJ; Drenos, Fotios F; Shah, Sonia S; Shah, Tina T; Palmen, Jutta J; Verzilli, Claudio C; Gaunt, Tom R TR; Pallas, Jacky J; Lovering, Ruth R; Li, Kawah K; Casas, Juan Pablo JP; Sofat, Reecha R; Kumari, Meena M; Rodriguez, Santiago S; Johnson, Toby T; Newhouse, Stephen J SJ; Dominiczak, Anna A; Samani, Nilesh J NJ; Caulfield, Mark M; Sever, Peter P; Stanton, Alice A; Shields, Denis C DC; Padmanabhan, Sandosh S; Melander, Olle O; Hastie, Claire C; Delles, Christian C; Ebrahim, Shah S; Marmot, Michael G MG; Smith, George Davey GD; Lawlor, Debbie A DA; Munroe, Patricia B PB; Day, Ian N IN; Kivimaki, Mika M; Whittaker, John J; Humphries, Steve E SE; Hingorani, Aroon D AD; , ; , ; ,