Variant ID: 1-55505647-G-A

NM_174936.3(PCSK9):c.137G>A;(p.R46H)

This variant was identified in 87 publications

View GRCh38 version.




Publications:


Genome-wide and phenome-wide analysis of ideal cardiovascular health in the VA Million Veteran Program.

Plos One
Huang, Rose D L RDL; Nguyen, Xuan-Mai T XT; Peloso, Gina M GM; Trinder, Mark M; Posner, Daniel C DC; Aragam, Krishna G KG; Ho, Yuk-Lam YL; Lynch, Julie A JA; Damrauer, Scott M SM; Chang, Kyong-Mi KM; Tsao, Philip S PS; Natarajan, Pradeep P; Assimes, Themistocles T; Gaziano, J Michael JM; Djousse, Luc L; Cho, Kelly K; Wilson, Peter W F PWF; Huffman, Jennifer E JE; O'Donnell, Christopher J CJ; ,
Publication Date: 2022

Variant appearance in text: rs11591147
PubMed Link: 35613103
Variant Present in the following documents:
  • Main text
  • pone.0267900.pdf
View BVdb publication page



Associations of genetically proxied inhibition of HMG-CoA reductase, NPC1L1, and PCSK9 with breast cancer and prostate cancer.

Breast Cancer Research : Bcr
Sun, Lulu L; Ding, Huan H; Jia, Yiming Y; Shi, Mengyao M; Guo, Daoxia D; Yang, Pinni P; Wang, Yu Y; Liu, Fanghua F; Zhang, Yonghong Y; Zhu, Zhengbao Z
Publication Date: 2022-02-12

Variant appearance in text: rs11591147
PubMed Link: 35151363
Variant Present in the following documents:
  • Main text
  • 13058_2022_Article_1508.pdf
View BVdb publication page



Machine Learning Revealed Ferroptosis Features and a Novel Ferroptosis-Based Classification for Diagnosis in Acute Myocardial Infarction.

Frontiers In Genetics
Huang, Dan D; Zheng, Shiya S; Liu, Zhuyuan Z; Zhu, Kongbo K; Zhi, Hong H; Ma, Genshan G
Publication Date: 2022

Variant appearance in text: rs11591147
PubMed Link: 35145551
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic Predisposition to Low-Density Lipoprotein Cholesterol May Increase Risks of Both Individual and Familial Alzheimer's Disease.

Frontiers In Medicine
Tan, Jiang-Shan JS; Hu, Meng-Jin MJ; Yang, Yan-Min YM; Yang, Yue-Jin YJ
Publication Date: 2021

Variant appearance in text: rs11591147
PubMed Link: 35087849
Variant Present in the following documents:
  • Main text
View BVdb publication page



Additive Effects of Genetic Interleukin-6 Signaling Downregulation and Low-Density Lipoprotein Cholesterol Lowering on Cardiovascular Disease: A 2×2 Factorial Mendelian Randomization Analysis.

Journal Of The American Heart Association
Georgakis, Marios K MK; Malik, Rainer R; Burgess, Stephen S; Dichgans, Martin M
Publication Date: 2021-12-20

Variant appearance in text: rs11591147
PubMed Link: 34927447
Variant Present in the following documents:
  • JAH3-11-e023277.pdf
  • JAH3-11-e023277-s001.pdf
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Variations in TM6SF2, PCSK9 and PCSK7 genes and risk of hepatic steatosis after liver transplantation: a cross-sectional study.

Bmc Gastroenterology
Eshraghian, Ahad A; Moasser, Elham E; Azarpira, Negar N; Fattahi, Mohammad Reza MR; Nikeghbalian, Saman S; Malek-Hosseini, Seyed Ali SA; Geramizadeh, Bita B
Publication Date: 2021-12-07

Variant appearance in text: rs11591147
PubMed Link: 34876018
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association Between Genetically Proxied Lipid-Lowering Drug Targets and Renal Cell Carcinoma: A Mendelian Randomization Study.

Frontiers In Nutrition
Liu, Luyang L; Sheng, Chao C; Lyu, Zhangyan Z; Dai, Hongji H; Chen, Kexin K
Publication Date: 2021

Variant appearance in text: rs11591147
PubMed Link: 34712689
Variant Present in the following documents:
  • Main text
  • fnut-08-755834.pdf
View BVdb publication page



Serum calcium and 25-hydroxyvitamin D in relation to longevity, cardiovascular disease and cancer: a Mendelian randomization study.

Npj Genomic Medicine
Yuan, Shuai S; Baron, John A JA; Michaëlsson, Karl K; Larsson, Susanna C SC
Publication Date: 2021-10-14

Variant appearance in text: rs11591147
PubMed Link: 34650087
Variant Present in the following documents:
  • 41525_2021_250_MOESM1_ESM.pdf
View BVdb publication page



Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease.

Nature Communications
Schmidt, Amand F AF; Hunt, Nicholas B NB; Gordillo-Marañón, Maria M; Charoen, Pimphen P; Drenos, Fotios F; Kivimaki, Mika M; Lawlor, Deborah A DA; Giambartolomei, Claudia C; Papacosta, Olia O; Chaturvedi, Nishi N; Bis, Joshua C JC; O'Donnell, Christopher J CJ; Wannamethee, Goya G; Wong, Andrew A; Price, Jackie F JF; Hughes, Alun D AD; Gaunt, Tom R TR; Franceschini, Nora N; Mook-Kanamori, Dennis O DO; Zwierzyna, Magdalena M; Sofat, Reecha R; Hingorani, Aroon D AD; Finan, Chris C
Publication Date: 2021-09-24

Variant appearance in text: rs11591147
PubMed Link: 34561430
Variant Present in the following documents:
  • 41467_2021_25703_MOESM1_ESM.pdf
View BVdb publication page



Mapping gene and gene pathways associated with coronary artery disease: a CARDIoGRAM exome and multi-ancestry UK biobank analysis.

Scientific Reports
Hariharan, Praveen P; Dupuis, Josée J
Publication Date: 2021-08-12

Variant appearance in text: rs11591147
PubMed Link: 34385509
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_95637.pdf
View BVdb publication page



A phenome-wide association study of genetically mimicked statins.

Bmc Medicine
Li, Shun S; Schooling, C M CM
Publication Date: 2021-06-30

Variant appearance in text: rs11591147
PubMed Link: 34187478
Variant Present in the following documents:
  • Main text
  • 12916_2021_Article_2013.pdf
View BVdb publication page



Genetic associations for two biological age measures point to distinct aging phenotypes.

Aging Cell
Kuo, Chia-Ling CL; Pilling, Luke C LC; Liu, Zuyun Z; Atkins, Janice L JL; Levine, Morgan E ME
Publication Date: 2021-06

Variant appearance in text: rs11591147
PubMed Link: 34038024
Variant Present in the following documents:
  • Main text
View BVdb publication page



Whole-genome sequencing analysis of semi-supercentenarians.

Elife
Garagnani, Paolo P; Marquis, Julien J; Delledonne, Massimo M; Pirazzini, Chiara C; Marasco, Elena E; Kwiatkowska, Katarzyna Malgorzata KM; Iannuzzi, Vincenzo V; Bacalini, Maria Giulia MG; Valsesia, Armand A; Carayol, Jerome J; Raymond, Frederic F; Ferrarini, Alberto A; Xumerle, Luciano L; Collino, Sebastiano S; Mari, Daniela D; Arosio, Beatrice B; Casati, Martina M; Ferri, Evelyn E; Monti, Daniela D; Nacmias, Benedetta B; Sorbi, Sandro S; Luiselli, Donata D; Pettener, Davide D; Castellani, Gastone G; Sala, Claudia C; Passarino, Giuseppe G; De Rango, Francesco F; D'Aquila, Patrizia P; Bertamini, Luca L; Martinelli, Nicola N; Girelli, Domenico D; Olivieri, Oliviero O; Giuliani, Cristina C; Descombes, Patrick P; Franceschi, Claudio C
Publication Date: 2021-05-04

Variant appearance in text: rs11591147
PubMed Link: 33941312
Variant Present in the following documents:
  • elife-57849-supp16.pdf
  • elife-57849-supp19.pdf
View BVdb publication page



Statistical Impact of Sample Size and Imbalance on Multivariate Analysis in silico and A Case Study in the UK Biobank.

Amia ... Annual Symposium Proceedings. Amia Symposium
Zhang, Xinyuan X; Li, Ruowang R; Ritchie, Marylyn D MD
Publication Date: 2020

Variant appearance in text: rs11591147
PubMed Link: 33936514
Variant Present in the following documents:
  • Main text
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Variants of PCSK9 Gene Are Associated with Subclinical Atherosclerosis and Cardiometabolic Parameters in Mexicans. The GEA Project.

Diagnostics (Basel, Switzerland)
Zamarrón-Licona, Erasmo E; Rodríguez-Pérez, José Manuel JM; Posadas-Sánchez, Rosalinda R; Vargas-Alarcón, Gilberto G; Baños-González, Manuel Alfonso MA; Borgonio-Cuadra, Verónica Marusa VM; Pérez-Hernández, Nonanzit N
Publication Date: 2021-04-26

Variant appearance in text: rs11591147
PubMed Link: 33925815
Variant Present in the following documents:
  • Main text
View BVdb publication page



PCSK9 and the Gut-Liver-Brain Axis: A Novel Therapeutic Target for Immune Regulation in Alcohol Use Disorder.

Journal Of Clinical Medicine
Lee, Ji Soo JS; O'Connell, Emma M EM; Pacher, Pal P; Lohoff, Falk W FW
Publication Date: 2021-04-18

Variant appearance in text: rs11591147
PubMed Link: 33919550
Variant Present in the following documents:
  • Main text
View BVdb publication page



Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study.

Plos Genetics
Gormley, Mark M; Yarmolinsky, James J; Dudding, Tom T; Burrows, Kimberley K; Martin, Richard M RM; Thomas, Steven S; Tyrrell, Jessica J; Brennan, Paul P; Pring, Miranda M; Boccia, Stefania S; Olshan, Andrew F AF; Diergaarde, Brenda B; Hung, Rayjean J RJ; Liu, Geoffrey G; Legge, Danny D; Tajara, Eloiza H EH; Severino, Patricia P; Lacko, Martin M; Ness, Andrew R AR; Davey Smith, George G; Vincent, Emma E EE; Richmond, Rebecca C RC
Publication Date: 2021-04

Variant appearance in text: rs11591147
PubMed Link: 33886544
Variant Present in the following documents:
  • pgen.1009525.s020.pdf
  • pgen.1009525.s016.pdf
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Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver.

Redox Biology
Zhong, Shanshan S; Li, Luxiao L; Liang, Ningning N; Zhang, Lili L; Xu, Xiaodong X; Chen, Shiting S; Yin, Huiyong H
Publication Date: 2021-05

Variant appearance in text: rs11591147
PubMed Link: 33740503
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Integrative Analysis of Transcriptome-Wide Association Study and mRNA Expression Profiles Identified Candidate Genes and Pathways Associated With Acute Myocardial Infarction.

Frontiers In Genetics
Chen, Guanzhong G; Liu, Liwei L; Li, Huanqiang H; Lun, Zhubin Z; Mai, Ziling Z; Lai, Wenguang W; Chen, Enzhao E; Zhou, Chunyun C; Yu, Sijia S; Yang, Junqing J; Chen, Shiqun S; Chen, Jiyan J; Liu, Yong Y
Publication Date: 2021

Variant appearance in text: rs11591147
PubMed Link: 33603775
Variant Present in the following documents:
  • Main text
  • fgene-12-616492.pdf
View BVdb publication page



Regulatory genomic circuitry of human disease loci by integrative epigenomics.

Nature
Boix, Carles A CA; James, Benjamin T BT; Park, Yongjin P YP; Meuleman, Wouter W; Kellis, Manolis M
Publication Date: 2021-02

Variant appearance in text: rs11591147
PubMed Link: 33536621
Variant Present in the following documents:
  • Main text
  • 41586_2020_Article_3145.pdf
View BVdb publication page



Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power.

Nature Genetics
Atkinson, Elizabeth G EG; Maihofer, Adam X AX; Kanai, Masahiro M; Martin, Alicia R AR; Karczewski, Konrad J KJ; Santoro, Marcos L ML; Ulirsch, Jacob C JC; Kamatani, Yoichiro Y; Okada, Yukinori Y; Finucane, Hilary K HK; Koenen, Karestan C KC; Nievergelt, Caroline M CM; Daly, Mark J MJ; Neale, Benjamin M BM
Publication Date: 2021-02

Variant appearance in text: rs11591147
PubMed Link: 33462486
Variant Present in the following documents:
  • NIHMS1655479-supplement-1.pdf
View BVdb publication page



Exploring the causal roles of circulating remnant lipid profile on cardiovascular and cerebrovascular diseases: Mendelian randomization study.

Journal Of Epidemiology
Si, Shucheng S; Hou, Lei L; Chen, Xiaolu X; Li, Wenchao W; Liu, Xinhui X; Liu, Congcong C; Li, Yunxia Y; Yuan, Tonghui T; Li, Jiqing J; Wang, Bojie B; Li, Hongkai H; Xue, Fuzhong F
Publication Date: 2021-01-13

Variant appearance in text: rs11591147
PubMed Link: 33441507
Variant Present in the following documents:
  • je-32-205-s001.pdf
View BVdb publication page



Familial Hypercholesterolemia in Russia: Three Decades of Genetic Studies.

Frontiers In Genetics
Vasilyev, Vadim V; Zakharova, Faina F; Bogoslovskay, Tatiana T; Mandelshtam, Mikhail M
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 33391333
Variant Present in the following documents:
View BVdb publication page



PCSK9 loss of function is protective against extra-coronary atherosclerotic cardiovascular disease in a large multi-ethnic cohort.

Plos One
Small, Aeron M AM; Huffman, Jennifer E JE; Klarin, Derek D; Lynch, Julie A JA; Assimes, Themistocles T; DuVall, Scott S; Sun, Yan V YV; Shere, Labiba L; Natarajan, Pradeep P; Gaziano, Michael M; Rader, Daniel J DJ; Wilson, Peter W F PWF; Tsao, Philip S PS; Chang, Kyong-Mi KM; Cho, Kelly K; O'Donnell, Christopher J CJ; Casas, Juan P JP; Damrauer, Scott M SM; ,
Publication Date: 2020

Variant appearance in text: rs11591147
PubMed Link: 33166319
Variant Present in the following documents:
  • Main text
  • pone.0239752.pdf
View BVdb publication page



Depression and cardiovascular risk-association among Beck Depression Inventory, PCSK9 levels and insulin resistance.

Cardiovascular Diabetology
Macchi, C C; Favero, C C; Ceresa, A A; Vigna, L L; Conti, D M DM; Pesatori, A C AC; Racagni, G G; Corsini, A A; Ferri, N N; Sirtori, C R CR; Buoli, M M; Bollati, V V; Ruscica, M M
Publication Date: 2020-11-03

Variant appearance in text: rs11591147
PubMed Link: 33143700
Variant Present in the following documents:
  • Main text
  • 12933_2020_Article_1158.pdf
View BVdb publication page



Inferring causal direction between two traits in the presence of horizontal pleiotropy with GWAS summary data.

Plos Genetics
Xue, Haoran H; Pan, Wei W
Publication Date: 2020-11

Variant appearance in text: rs11591147
PubMed Link: 33137120
Variant Present in the following documents:
  • pgen.1009105.s004.pdf
View BVdb publication page



Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale.

Nature Genetics
Li, Xihao X; Li, Zilin Z; Zhou, Hufeng H; Gaynor, Sheila M SM; Liu, Yaowu Y; Chen, Han H; Sun, Ryan R; Dey, Rounak R; Arnett, Donna K DK; Aslibekyan, Stella S; Ballantyne, Christie M CM; Bielak, Lawrence F LF; Blangero, John J; Boerwinkle, Eric E; Bowden, Donald W DW; Broome, Jai G JG; Conomos, Matthew P MP; Correa, Adolfo A; Cupples, L Adrienne LA; Curran, Joanne E JE; Freedman, Barry I BI; Guo, Xiuqing X; Hindy, George G; Irvin, Marguerite R MR; Kardia, Sharon L R SLR; Kathiresan, Sekar S; Khan, Alyna T AT; Kooperberg, Charles L CL; Laurie, Cathy C CC; Liu, X Shirley XS; Mahaney, Michael C MC; Manichaikul, Ani W AW; Martin, Lisa W LW; Mathias, Rasika A RA; McGarvey, Stephen T ST; Mitchell, Braxton D BD; Montasser, May E ME; Moore, Jill E JE; Morrison, Alanna C AC; O'Connell, Jeffrey R JR; Palmer, Nicholette D ND; Pampana, Akhil A; Peralta, Juan M JM; Peyser, Patricia A PA; Psaty, Bruce M BM; Redline, Susan S; Rice, Kenneth M KM; Rich, Stephen S SS; Smith, Jennifer A JA; Tiwari, Hemant K HK; Tsai, Michael Y MY; Vasan, Ramachandran S RS; Wang, Fei Fei FF; Weeks, Daniel E DE; Weng, Zhiping Z; Wilson, James G JG; Yanek, Lisa R LR; , ; , ; Neale, Benjamin M BM; Sunyaev, Shamil R SR; Abecasis, Gonçalo R GR; Rotter, Jerome I JI; Willer, Cristen J CJ; Peloso, Gina M GM; Natarajan, Pradeep P; Lin, Xihong X
Publication Date: 2020-09

Variant appearance in text: rs11591147
PubMed Link: 32839606
Variant Present in the following documents:
  • Main text
View BVdb publication page



Characterization of Exome Variants and Their Metabolic Impact in 6,716 American Indians from the Southwest US.

American Journal Of Human Genetics
Kim, Hye In HI; Ye, Bin B; Gosalia, Nehal N; , ; Köroğlu, Çiğdem Ç; Hanson, Robert L RL; Hsueh, Wen-Chi WC; Knowler, William C WC; Baier, Leslie J LJ; Bogardus, Clifton C; Shuldiner, Alan R AR; Van Hout, Cristopher V CV
Publication Date: 2020-08-06

Variant appearance in text: rs11591147
PubMed Link: 32640185
Variant Present in the following documents:
  • Main text
View BVdb publication page



Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels.

Circulation. Genomic And Precision Medicine
Wang, Zhe Z; Chen, Han H; Bartz, Traci M TM; Bielak, Lawrence F LF; Chasman, Daniel I DI; Feitosa, Mary F MF; Franceschini, Nora N; Guo, Xiuqing X; Lim, Elise E; Noordam, Raymond R; Richard, Melissa A MA; Wang, Heming H; Cade, Brian B; Cupples, L Adrienne LA; de Vries, Paul S PS; Giulanini, Franco F; Lee, Jiwon J; Lemaitre, Rozenn N RN; Martin, Lisa W LW; Reiner, Alex P AP; Rich, Stephen S SS; Schreiner, Pamela J PJ; Sidney, Stephen S; Sitlani, Colleen M CM; Smith, Jennifer A JA; Willems van Dijk, Ko K; Yao, Jie J; Zhao, Wei W; Fornage, Myriam M; Kardia, Sharon L R SLR; Kooperberg, Charles C; Liu, Ching-Ti CT; Mook-Kanamori, Dennis O DO; Province, Michael A MA; Psaty, Bruce M BM; Redline, Susan S; Ridker, Paul M PM; Rotter, Jerome I JI; Boerwinkle, Eric E; Morrison, Alanna C AC; ,
Publication Date: 2020-08

Variant appearance in text: rs11591147
PubMed Link: 32510982
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pleiotropy-Based Decomposition of Genetic Risk Scores: Association and Interaction Analysis for Type 2 Diabetes and CAD.

American Journal Of Human Genetics
Chasman, Daniel I DI; Giulianini, Franco F; Demler, Olga V OV; Udler, Miriam S MS
Publication Date: 2020-05-07

Variant appearance in text: rs11591147
PubMed Link: 32302534
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer.

Jama
Yarmolinsky, James J; Bull, Caroline J CJ; Vincent, Emma E EE; Robinson, Jamie J; Walther, Axel A; Smith, George Davey GD; Lewis, Sarah J SJ; Relton, Caroline L CL; Martin, Richard M RM
Publication Date: 2020-02-18

Variant appearance in text: rs11591147
PubMed Link: 32068819
Variant Present in the following documents:
  • Main text
View BVdb publication page



Identifying cross-disease components of genetic risk across hospital data in the UK Biobank.

Nature Genetics
Cortes, Adrian A; Albers, Patrick K PK; Dendrou, Calliope A CA; Fugger, Lars L; McVean, Gil G
Publication Date: 2020-01

Variant appearance in text: PCSK9: Arg46His; rs11591147
PubMed Link: 31873298
Variant Present in the following documents:
  • Main text
View BVdb publication page



Management of Lipid Abnormalities in Patients with Diabetes.

Current Cardiology Reports
Sillars, Anne A; Sattar, Naveed N
Publication Date: 2019-11-22

Variant appearance in text: rs11591147
PubMed Link: 31758270
Variant Present in the following documents:
  • Main text
View BVdb publication page



Lipid lowering and Alzheimer disease risk: A mendelian randomization study.

Annals Of Neurology
Williams, Dylan M DM; Finan, Chris C; Schmidt, Amand F AF; Burgess, Stephen S; Hingorani, Aroon D AD
Publication Date: 2020-01

Variant appearance in text: rs11591147
PubMed Link: 31714636
Variant Present in the following documents:
  • Main text
View BVdb publication page



The role of proprotein convertase subtilisin-kexin type 9 (PCSK9) in the vascular aging process - is there a link?

Kardiochirurgia I Torakochirurgia Polska = Polish Journal Of Cardio-Thoracic Surgery
Grobelna, Malwina K MK; Strauss, Ewa E; Krasiński, Zbigniew Z
Publication Date: 2019-10

Variant appearance in text: rs11591147
PubMed Link: 31708986
Variant Present in the following documents:
  • Main text
View BVdb publication page



Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.

Bmc Cardiovascular Disorders
Schmidt, Amand F AF; Holmes, Michael V MV; Preiss, David D; Swerdlow, Daniel I DI; Denaxas, Spiros S; Fatemifar, Ghazaleh G; Faraway, Rupert R; Finan, Chris C; Valentine, Dennis D; Fairhurst-Hunter, Zammy Z; Hartwig, Fernando Pires FP; Horta, Bernardo Lessa BL; Hypponen, Elina E; Power, Christine C; Moldovan, Max M; van Iperen, Erik E; Hovingh, Kees K; Demuth, Ilja I; Norman, Kristina K; Steinhagen-Thiessen, Elisabeth E; Demuth, Juri J; Bertram, Lars L; Lill, Christina M CM; Coassin, Stefan S; Willeit, Johann J; Kiechl, Stefan S; Willeit, Karin K; Mason, Dan D; Wright, John J; Morris, Richard R; Wanamethee, Goya G; Whincup, Peter P; Ben-Shlomo, Yoav Y; McLachlan, Stela S; Price, Jackie F JF; Kivimaki, Mika M; Welch, Catherine C; Sanchez-Galvez, Adelaida A; Marques-Vidal, Pedro P; Nicolaides, Andrew A; Panayiotou, Andrie G AG; Onland-Moret, N Charlotte NC; van der Schouw, Yvonne T YT; Matullo, Giuseppe G; Fiorito, Giovanni G; Guarrera, Simonetta S; Sacerdote, Carlotta C; Wareham, Nicholas J NJ; Langenberg, Claudia C; Scott, Robert A RA; Luan, Jian'an J; Bobak, Martin M; Malyutina, Sofia S; Pająk, Andrzej A; Kubinova, Ruzena R; Tamosiunas, Abdonas A; Pikhart, Hynek H; Grarup, Niels N; Pedersen, Oluf O; Hansen, Torben T; Linneberg, Allan A; Jess, Tine T; Cooper, Jackie J; Humphries, Steve E SE; Brilliant, Murray M; Kitchner, Terrie T; Hakonarson, Hakon H; Carrell, David S DS; McCarty, Catherine A CA; Lester, Kirchner H KH; Larson, Eric B EB; Crosslin, David R DR; de Andrade, Mariza M; Roden, Dan M DM; Denny, Joshua C JC; Carty, Cara C; Hancock, Stephen S; Attia, John J; Holliday, Elizabeth E; Scott, Rodney R; Schofield, Peter P; O'Donnell, Martin M; Yusuf, Salim S; Chong, Michael M; Pare, Guillaume G; van der Harst, Pim P; Said, M Abdullah MA; Eppinga, Ruben N RN; Verweij, Niek N; Snieder, Harold H; , ; Christen, Tim T; Mook-Kanamori, D O DO; , ; Gustafsson, Stefan S; Lind, Lars L; Ingelsson, Erik E; Pazoki, Raha R; Franco, Oscar O; Hofman, Albert A; Uitterlinden, Andre A; Dehghan, Abbas A; Teumer, Alexander A; Baumeister, Sebastian S; Dörr, Marcus M; Lerch, Markus M MM; Völker, Uwe U; Völzke, Henry H; Ward, Joey J; Pell, Jill P JP; Meade, Tom T; Christophersen, Ingrid E IE; Maitland-van der Zee, Anke H AH; Baranova, Ekaterina V EV; Young, Robin R; Ford, Ian I; Campbell, Archie A; Padmanabhan, Sandosh S; Bots, Michiel L ML; Grobbee, Diederick E DE; Froguel, Philippe P; Thuillier, Dorothée D; Roussel, Ronan R; Bonnefond, Amélie A; Cariou, Bertrand B; Smart, Melissa M; Bao, Yanchun Y; Kumari, Meena M; Mahajan, Anubha A; Hopewell, Jemma C JC; Seshadri, Sudha S; , ; Dale, Caroline C; Costa, Rui Providencia E RPE; Ridker, Paul M PM; Chasman, Daniel I DI; Reiner, Alex P AP; Ritchie, Marylyn D MD; Lange, Leslie A LA; Cornish, Alex J AJ; Dobbins, Sara E SE; Hemminki, Kari K; Kinnersley, Ben B; Sanson, Marc M; Labreche, Karim K; Simon, Matthias M; Bondy, Melissa M; Law, Philip P; Speedy, Helen H; Allan, James J; Li, Ni N; Went, Molly M; Weinhold, Niels N; Morgan, Gareth G; Sonneveld, Pieter P; Nilsson, Björn B; Goldschmidt, Hartmut H; Sud, Amit A; Engert, Andreas A; Hansson, Markus M; Hemingway, Harry H; Asselbergs, Folkert W FW; Patel, Riyaz S RS; Keating, Brendan J BJ; Sattar, Naveed N; Houlston, Richard R; Casas, Juan P JP; Hingorani, Aroon D AD
Publication Date: 2019-10-29

Variant appearance in text: rs11591147
PubMed Link: 31664920
Variant Present in the following documents:
  • Main text
View BVdb publication page



A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context.

Nature Communications
Gallois, Apolline A; Mefford, Joel J; Ko, Arthur A; Vaysse, Amaury A; Julienne, Hanna H; Ala-Korpela, Mika M; Laakso, Markku M; Zaitlen, Noah N; Pajukanta, Päivi P; Aschard, Hugues H
Publication Date: 2019-10-21

Variant appearance in text: rs11591147
PubMed Link: 31636271
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Genetic Approach to the Association Between PCSK9 and Sepsis.

Jama Network Open
Feng, QiPing Q; Wei, Wei-Qi WQ; Chaugai, Sandip S; Carranza Leon, Barbara G BG; Kawai, Vivian V; Carranza Leon, Daniel A DA; Jiang, Lan L; Zhong, Xue X; Liu, Ge G; Ihegword, Andrea A; Shaffer, Christian M CM; Linton, MacRae F MF; Chung, Cecilia P CP; Stein, C Michael CM
Publication Date: 2019-09-04

Variant appearance in text: rs11591147
PubMed Link: 31509211
Variant Present in the following documents:
  • Main text
View BVdb publication page



Coronary artery disease, genetic risk and the metabolome in young individuals.

Wellcome Open Research
Battram, Thomas T; Hoskins, Luke L; Hughes, David A DA; Kettunen, Johannes J; Ring, Susan M SM; Davey Smith, George G; Timpson, Nicholas J NJ
Publication Date: 2018

Variant appearance in text: rs11591147
PubMed Link: 30740535
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Association of Triglyceride-Lowering LPL Variants and LDL-C-Lowering LDLR Variants With Risk of Coronary Heart Disease.

Jama
Ference, Brian A BA; Kastelein, John J P JJP; Ray, Kausik K KK; Ginsberg, Henry N HN; Chapman, M John MJ; Packard, Chris J CJ; Laufs, Ulrich U; Oliver-Williams, Clare C; Wood, Angela M AM; Butterworth, Adam S AS; Di Angelantonio, Emanuele E; Danesh, John J; Nicholls, Stephen J SJ; Bhatt, Deepak L DL; Sabatine, Marc S MS; Catapano, Alberico L AL
Publication Date: 2019-01-29

Variant appearance in text: rs11591147
PubMed Link: 30694319
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Causal effects of blood lipids on amyotrophic lateral sclerosis: a Mendelian randomization study.

Human Molecular Genetics
Zeng, Ping P; Zhou, Xiang X
Publication Date: 2019-02-15

Variant appearance in text: rs11591147
PubMed Link: 30445611
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GWAS Reveal Targets in Vessel Wall Pathways to Treat Coronary Artery Disease.

Frontiers In Cardiovascular Medicine
Turner, Adam W AW; Wong, Doris D; Dreisbach, Caitlin N CN; Miller, Clint L CL
Publication Date: 2018

Variant appearance in text: rs11591147
PubMed Link: 29988570
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Risk of Neuropsychiatric Adverse Effects of Lipid-Lowering Drugs: A Mendelian Randomization Study.

The International Journal Of Neuropsychopharmacology
Alghamdi, Jahad J; Matou-Nasri, Sabine S; Alghamdi, Faisal F; Alghamdi, Saleh S; Alfadhel, Majid M; Padmanabhan, Sandosh S
Publication Date: 2018-12-01

Variant appearance in text: rs11591147
PubMed Link: 29986042
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Multilocus Analysis of Genetic Susceptibility to Myocardial Infarction in Russians: Replication Study.

Acta Naturae
Kukava, N G NG; Titov, B V BV; Osmak, G J GJ; Matveeva, N A NA; Kulakova, O G OG; Favorov, A V AV; Shakhnovich, R M RM; Ruda, M Ya MY; Favorova, O O OO
Publication Date: 2017

Variant appearance in text: rs11591147
PubMed Link: 29340220
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A Review of Pathway-Based Analysis Tools That Visualize Genetic Variants.

Frontiers In Genetics
Cirillo, Elisa E; Parnell, Laurence D LD; Evelo, Chris T CT
Publication Date: 2017

Variant appearance in text: rs11591147
PubMed Link: 29163640
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The impact of rare and low-frequency genetic variants in common disease.

Genome Biology
Bomba, Lorenzo L; Walter, Klaudia K; Soranzo, Nicole N
Publication Date: 2017-04-27

Variant appearance in text: rs11591147
PubMed Link: 28449691
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Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.

Genome Medicine
Nagy, Reka R; Boutin, Thibaud S TS; Marten, Jonathan J; Huffman, Jennifer E JE; Kerr, Shona M SM; Campbell, Archie A; Evenden, Louise L; Gibson, Jude J; Amador, Carmen C; Howard, David M DM; Navarro, Pau P; Morris, Andrew A; Deary, Ian J IJ; Hocking, Lynne J LJ; Padmanabhan, Sandosh S; Smith, Blair H BH; Joshi, Peter P; Wilson, James F JF; Hastie, Nicholas D ND; Wright, Alan F AF; McIntosh, Andrew M AM; Porteous, David J DJ; Haley, Chris S CS; Vitart, Veronique V; Hayward, Caroline C
Publication Date: 2017-03-07

Variant appearance in text: rs11591147
PubMed Link: 28270201
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The Relationship Between Coronary Artery Disease and Genetic Polymorphisms of Melanoma Inhibitory Activity 3.

Iranian Red Crescent Medical Journal
Zaimkohan, Hooshang H; Keramatipour, Mohammad M; Mirhafez, Seyed Reza SR; Tavakkoly-Bazzaz, Javad J; Tahooni, Azadeh A; Piryaei, Mohammad M; Ghayour-Mobarhan, Majid M; Ghaderian, Seyed Mohammad Hossein SM
Publication Date: 2016-09

Variant appearance in text: rs11591147
PubMed Link: 28180021
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PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.

The Lancet. Diabetes & Endocrinology
Schmidt, Amand F AF; Swerdlow, Daniel I DI; Holmes, Michael V MV; Patel, Riyaz S RS; Fairhurst-Hunter, Zammy Z; Lyall, Donald M DM; Hartwig, Fernando Pires FP; Horta, Bernardo Lessa BL; Hyppönen, Elina E; Power, Christine C; Moldovan, Max M; van Iperen, Erik E; Hovingh, G Kees GK; Demuth, Ilja I; Norman, Kristina K; Steinhagen-Thiessen, Elisabeth E; Demuth, Juri J; Bertram, Lars L; Liu, Tian T; Coassin, Stefan S; Willeit, Johann J; Kiechl, Stefan S; Willeit, Karin K; Mason, Dan D; Wright, John J; Morris, Richard R; Wanamethee, Goya G; Whincup, Peter P; Ben-Shlomo, Yoav Y; McLachlan, Stela S; Price, Jackie F JF; Kivimaki, Mika M; Welch, Catherine C; Sanchez-Galvez, Adelaida A; Marques-Vidal, Pedro P; Nicolaides, Andrew A; Panayiotou, Andrie G AG; Onland-Moret, N Charlotte NC; van der Schouw, Yvonne T YT; Matullo, Giuseppe G; Fiorito, Giovanni G; Guarrera, Simonetta S; Sacerdote, Carlotta C; Wareham, Nicholas J NJ; Langenberg, Claudia C; Scott, Robert R; Luan, Jian'an J; Bobak, Martin M; Malyutina, Sofia S; Pająk, Andrzej A; Kubinova, Ruzena R; Tamosiunas, Abdonas A; Pikhart, Hynek H; Husemoen, Lise Lotte Nystrup LL; Grarup, Niels N; Pedersen, Oluf O; Hansen, Torben T; Linneberg, Allan A; Simonsen, Kenneth Starup KS; Cooper, Jackie J; Humphries, Steve E SE; Brilliant, Murray M; Kitchner, Terrie T; Hakonarson, Hakon H; Carrell, David S DS; McCarty, Catherine A CA; Kirchner, H Lester HL; Larson, Eric B EB; Crosslin, David R DR; de Andrade, Mariza M; Roden, Dan M DM; Denny, Joshua C JC; Carty, Cara C; Hancock, Stephen S; Attia, John J; Holliday, Elizabeth E; O'Donnell, Martin M; Yusuf, Salim S; Chong, Michael M; Pare, Guillaume G; van der Harst, Pim P; Said, M Abdullah MA; Eppinga, Ruben N RN; Verweij, Niek N; Snieder, Harold H; , ; Christen, Tim T; Mook-Kanamori, Dennis O DO; Gustafsson, Stefan S; Lind, Lars L; Ingelsson, Erik E; Pazoki, Raha R; Franco, Oscar O; Hofman, Albert A; Uitterlinden, Andre A; Dehghan, Abbas A; Teumer, Alexander A; Baumeister, Sebastian S; Dörr, Marcus M; Lerch, Markus M MM; Völker, Uwe U; Völzke, Henry H; Ward, Joey J; Pell, Jill P JP; Smith, Daniel J DJ; Meade, Tom T; Maitland-van der Zee, Anke H AH; Baranova, Ekaterina V EV; Young, Robin R; Ford, Ian I; Campbell, Archie A; Padmanabhan, Sandosh S; Bots, Michiel L ML; Grobbee, Diederick E DE; Froguel, Philippe P; Thuillier, Dorothée D; Balkau, Beverley B; Bonnefond, Amélie A; Cariou, Bertrand B; Smart, Melissa M; Bao, Yanchun Y; Kumari, Meena M; Mahajan, Anubha A; Ridker, Paul M PM; Chasman, Daniel I DI; Reiner, Alex P AP; Lange, Leslie A LA; Ritchie, Marylyn D MD; Asselbergs, Folkert W FW; Casas, Juan-Pablo JP; Keating, Brendan J BJ; Preiss, David D; Hingorani, Aroon D AD; , ; Sattar, Naveed N
Publication Date: 2017-02

Variant appearance in text: rs11591147
PubMed Link: 27908689
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A 19-SNP coronary heart disease gene score profile in subjects with type 2 diabetes: the coronary heart disease risk in type 2 diabetes (CoRDia study) study baseline characteristics.

Cardiovascular Diabetology
Beaney, Katherine E KE; Ward, Claire E CE; Bappa, Dauda A S DA; McGale, Nadine N; Davies, Anna K AK; Hirani, Shashivadan P SP; Li, KaWah K; Howard, Philip P; Vance, Dwaine R DR; Crockard, Martin A MA; Lamont, John V JV; Newman, Stanton S; Humphries, Steve E SE
Publication Date: 2016-10-03

Variant appearance in text: rs11591147
PubMed Link: 27716211
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Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps.

Nature Genetics
Iotchkova, Valentina V; Huang, Jie J; Morris, John A JA; Jain, Deepti D; Barbieri, Caterina C; Walter, Klaudia K; Min, Josine L JL; Chen, Lu L; Astle, William W; Cocca, Massimilian M; Deelen, Patrick P; Elding, Heather H; Farmaki, Aliki-Eleni AE; Franklin, Christopher S CS; Franberg, Mattias M; Gaunt, Tom R TR; Hofman, Albert A; Jiang, Tao T; Kleber, Marcus E ME; Lachance, Genevieve G; Luan, Jian'an J; Malerba, Giovanni G; Matchan, Angela A; Mead, Daniel D; Memari, Yasin Y; Ntalla, Ioanna I; Panoutsopoulou, Kalliope K; Pazoki, Raha R; Perry, John R B JRB; Rivadeneira, Fernando F; Sabater-Lleal, Maria M; Sennblad, Bengt B; Shin, So-Youn SY; Southam, Lorraine L; Traglia, Michela M; van Dijk, Freerk F; van Leeuwen, Elisabeth M EM; Zaza, Gianluigi G; Zhang, Weihua W; , ; Amin, Najaf N; Butterworth, Adam A; Chambers, John C JC; Dedoussis, George G; Dehghan, Abbas A; Franco, Oscar H OH; Franke, Lude L; Frontini, Mattia M; Gambaro, Giovanni G; Gasparini, Paolo P; Hamsten, Anders A; Issacs, Aaron A; Kooner, Jaspal S JS; Kooperberg, Charles C; Langenberg, Claudia C; Marz, Winfried W; Scott, Robert A RA; Swertz, Morris A MA; Toniolo, Daniela D; Uitterlinden, Andre G AG; van Duijn, Cornelia M CM; Watkins, Hugh H; Zeggini, Eleftheria E; Maurano, Mathew T MT; Timpson, Nicholas J NJ; Reiner, Alexander P AP; Auer, Paul L PL; Soranzo, Nicole N
Publication Date: 2016-11

Variant appearance in text: rs11591147
PubMed Link: 27668658
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Comparison of variance estimators for meta-analysis of instrumental variable estimates.

International Journal Of Epidemiology
Schmidt, A F AF; Hingorani, A D AD; Jefferis, B J BJ; White, J J; Groenwold, Rhh R; Dudbridge, F F; ,
Publication Date: 2016-12-01

Variant appearance in text: rs11591147
PubMed Link: 27591262
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Analysis with the exome array identifies multiple new independent variants in lipid loci.

Human Molecular Genetics
Kanoni, Stavroula S; Masca, Nicholas G D NG; Stirrups, Kathleen E KE; Varga, Tibor V TV; Warren, Helen R HR; Scott, Robert A RA; Southam, Lorraine L; Zhang, Weihua W; Yaghootkar, Hanieh H; Müller-Nurasyid, Martina M; Couto Alves, Alexessander A; Strawbridge, Rona J RJ; Lataniotis, Lazaros L; An Hashim, Nikman N; Besse, Céline C; Boland, Anne A; Braund, Peter S PS; Connell, John M JM; Dominiczak, Anna A; Farmaki, Aliki-Eleni AE; Franks, Stephen S; Grallert, Harald H; Jansson, Jan-Håkan JH; Karaleftheri, Maria M; Keinänen-Kiukaanniemi, Sirkka S; Matchan, Angela A; Pasko, Dorota D; Peters, Annette A; Poulter, Neil N; Rayner, Nigel W NW; Renström, Frida F; Rolandsson, Olov O; Sabater-Lleal, Maria M; Sennblad, Bengt B; Sever, Peter P; Shields, Denis D; Silveira, Angela A; Stanton, Alice V AV; Strauch, Konstantin K; Tomaszewski, Maciej M; Tsafantakis, Emmanouil E; Waldenberger, Melanie M; Blakemore, Alexandra I F AI; Dedoussis, George G; Escher, Stefan A SA; Kooner, Jaspal S JS; McCarthy, Mark I MI; Palmer, Colin N A CN; , ; Hamsten, Anders A; Caulfield, Mark J MJ; Frayling, Timothy M TM; Tobin, Martin D MD; Jarvelin, Marjo-Riitta MR; Zeggini, Eleftheria E; Gieger, Christian C; Chambers, John C JC; Wareham, Nick J NJ; Munroe, Patricia B PB; Franks, Paul W PW; Samani, Nilesh J NJ; Deloukas, Panos P
Publication Date: 2016-09-15

Variant appearance in text: rs11591147
PubMed Link: 27466198
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Influence of Genetic Risk Factors on Coronary Heart Disease Occurrence in Afro-Caribbeans.

The Canadian Journal Of Cardiology
Larifla, Laurent L; Beaney, Katherine E KE; Foucan, Lydia L; Bangou, Jacqueline J; Michel, Carl T CT; Martino, Jean J; Velayoudom-Cephise, Fritz-Line FL; Cooper, Jackie A JA; Humphries, Steve E SE
Publication Date: 2016-08

Variant appearance in text: rs11591147
PubMed Link: 26971241
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FINEMAP: efficient variable selection using summary data from genome-wide association studies.

Bioinformatics (Oxford, England)
Benner, Christian C; Spencer, Chris C A CC; Havulinna, Aki S AS; Salomaa, Veikko V; Ripatti, Samuli S; Pirinen, Matti M
Publication Date: 2016-05-15

Variant appearance in text: rs11591147
PubMed Link: 26773131
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Association between the DOCK7, PCSK9 and GALNT2 Gene Polymorphisms and Serum Lipid levels.

Scientific Reports
Guo, Tao T; Yin, Rui-Xing RX; Huang, Feng F; Yao, Li-Mei LM; Lin, Wei-Xiong WX; Pan, Shang-Ling SL
Publication Date: 2016-01-08

Variant appearance in text: rs11591147
PubMed Link: 26744084
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Networks in Coronary Heart Disease Genetics As a Step towards Systems Epidemiology.

Plos One
Drenos, Fotios F; Grossi, Enzo E; Buscema, Massimo M; Humphries, Steve E SE
Publication Date: 2015

Variant appearance in text: rs11591147
PubMed Link: 25951190
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Developing genomic knowledge bases and databases to support clinical management: current perspectives.

Pharmacogenomics And Personalized Medicine
Huser, Vojtech V; Sincan, Murat M; Cimino, James J JJ
Publication Date: 2014

Variant appearance in text: rs11591147
PubMed Link: 25276091
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Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program.

Atherosclerosis
Simino, Jeannette J; Kume, Rezart R; Kraja, Aldi T AT; Turner, Stephen T ST; Hanis, Craig L CL; Sheu, Wayne W; Chen, Ida I; Jaquish, Cashell C; Cooper, Richard S RS; Chakravarti, Aravinda A; Quertermous, Thomas T; Boerwinkle, Eric E; Hunt, Steven C SC; Rao, D C DC
Publication Date: 2014-07

Variant appearance in text: rs11591147
PubMed Link: 24819747
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Pharmacogenetics in cardiovascular disease: the challenge of moving from promise to realization: concepts discussed at the Canadian Network and Centre for Trials Internationally Network Conference (CANNeCTIN), June 2009.

Clinical Cardiology
Joseph, Philip G PG; Pare, Guillaume G; Ross, Stephanie S; Roberts, Robert R; Anand, Sonia S SS
Publication Date: 2014-01

Variant appearance in text: rs11591147
PubMed Link: 24105892
Variant Present in the following documents:
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No evidence of interaction between known lipid-associated genetic variants and smoking in the multi-ethnic PAGE population.

Human Genetics
Dumitrescu, Logan L; Carty, Cara L CL; Franceschini, Nora N; Hindorff, Lucia A LA; Cole, Shelley A SA; Bůžková, Petra P; Schumacher, Fredrick R FR; Eaton, Charles B CB; Goodloe, Robert J RJ; Duggan, David J DJ; Haessler, Jeff J; Cochran, Barbara B; Henderson, Brian E BE; Cheng, Iona I; Johnson, Karen C KC; Carlson, Chris S CS; Love, Shelly-Anne SA; Brown-Gentry, Kristin K; Nato, Alejandro Q AQ; Quibrera, Miguel M; Shohet, Ralph V RV; Ambite, José Luis JL; Wilkens, Lynne R LR; Le Marchand, Loïc L; Haiman, Christopher A CA; Buyske, Steven S; Kooperberg, Charles C; North, Kari E KE; Fornage, Myriam M; Crawford, Dana C DC
Publication Date: 2013-12

Variant appearance in text: rs11591147
PubMed Link: 24100633
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The association of common SNPs and haplotypes in CETP gene with HDL cholesterol levels in Latvian population.

Plos One
Radovica, Ilze I; Fridmanis, Davids D; Vaivade, Iveta I; Nikitina-Zake, Liene L; Klovins, Janis J
Publication Date: 2013

Variant appearance in text: rs11591147
PubMed Link: 23675527
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Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network.

Plos Genetics
Pendergrass, Sarah A SA; Brown-Gentry, Kristin K; Dudek, Scott S; Frase, Alex A; Torstenson, Eric S ES; Goodloe, Robert R; Ambite, Jose Luis JL; Avery, Christy L CL; Buyske, Steve S; Bůžková, Petra P; Deelman, Ewa E; Fesinmeyer, Megan D MD; Haiman, Christopher A CA; Heiss, Gerardo G; Hindorff, Lucia A LA; Hsu, Chu-Nan CN; Jackson, Rebecca D RD; Kooperberg, Charles C; Le Marchand, Loic L; Lin, Yi Y; Matise, Tara C TC; Monroe, Kristine R KR; Moreland, Larry L; Park, Sungshim L SL; Reiner, Alex A; Wallace, Robert R; Wilkens, Lynn R LR; Crawford, Dana C DC; Ritchie, Marylyn D MD
Publication Date: 2013

Variant appearance in text: rs11591147
PubMed Link: 23382687
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PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or noncardiovascular clinical events in an elderly population.

Journal Of Lipid Research
Postmus, Iris I; Trompet, Stella S; de Craen, Anton J M AJ; Buckley, Brendan M BM; Ford, Ian I; Stott, David J DJ; Sattar, Naveed N; Slagboom, P Eline PE; Westendorp, Rudi G J RG; Jukema, J Wouter JW
Publication Date: 2013-02

Variant appearance in text: rs11591147
PubMed Link: 23300213
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Polymorphisms in the fetal progesterone receptor and a calcium-activated potassium channel isoform are associated with preterm birth in an Argentinian population.

Journal Of Perinatology : Official Journal Of The California Perinatal Association
Mann, P C PC; Cooper, M E ME; Ryckman, K K KK; Comas, B B; Gili, J J; Crumley, S S; Bream, E N A EN; Byers, H M HM; Piester, T T; Schaefer, A A; Christine, P J PJ; Lawrence, A A; Schaa, K L KL; Kelsey, K J P KJ; Berends, S K SK; Momany, A M AM; Gadow, E E; Cosentino, V V; Castilla, E E EE; López Camelo, J J; Saleme, C C; Day, L J LJ; England, S K SK; Marazita, M L ML; Dagle, J M JM; Murray, J C JC
Publication Date: 2013-05

Variant appearance in text: rs11591147
PubMed Link: 23018797
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Investigation of genetic risk factors for chronic adult diseases for association with preterm birth.

Human Genetics
Falah, Nadia N; McElroy, Jude J; Snegovskikh, Victoria V; Lockwood, Charles J CJ; Norwitz, Errol E; Murray, Jeffey C JC; Kuczynski, Edward E; Menon, Ramkumar R; Teramo, Kari K; Muglia, Louis J LJ; Morgan, Thomas T
Publication Date: 2013-01

Variant appearance in text: rs11591147
PubMed Link: 22972380
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Prioritizing genetic variants for causality on the basis of preferential linkage disequilibrium.

American Journal Of Human Genetics
Zhu, Qianqian Q; Ge, Dongliang D; Heinzen, Erin L EL; Dickson, Samuel P SP; Urban, Thomas J TJ; Zhu, Mingfu M; Maia, Jessica M JM; He, Min M; Zhao, Qian Q; Shianna, Kevin V KV; Goldstein, David B DB
Publication Date: 2012-09-07

Variant appearance in text: rs11591147
PubMed Link: 22939045
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Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.

Plos One
Musunuru, Kiran K; Romaine, Simon P R SP; Lettre, Guillaume G; Wilson, James G JG; Volcik, Kelly A KA; Tsai, Michael Y MY; Taylor, Herman A HA; Schreiner, Pamela J PJ; Rotter, Jerome I JI; Rich, Stephen S SS; Redline, Susan S; Psaty, Bruce M BM; Papanicolaou, George J GJ; Ordovas, Jose M JM; Liu, Kiang K; Krauss, Ronald M RM; Glazer, Nicole L NL; Gabriel, Stacey B SB; Fornage, Myriam M; Cupples, L Adrienne LA; Buxbaum, Sarah G SG; Boerwinkle, Eric E; Ballantyne, Christie M CM; Kathiresan, Sekar S; Rader, Daniel J DJ
Publication Date: 2012

Variant appearance in text: rs11591147
PubMed Link: 22629316
Variant Present in the following documents:
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Low-density lipoprotein cholesterol, apolipoprotein B, and risk of coronary heart disease: from familial hyperlipidemia to genomics.

Biological Research For Nursing
Imes, Christopher C CC; Austin, Melissa A MA
Publication Date: 2013-07

Variant appearance in text: rs11591147
PubMed Link: 22531366
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Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a).

Journal Of Lipid Research
Deshmukh, Harshal A HA; Colhoun, Helen M HM; Johnson, Toby T; McKeigue, Paul M PM; Betteridge, D John DJ; Durrington, Paul N PN; Fuller, John H JH; Livingstone, Shona S; Charlton-Menys, Valentine V; Neil, Andrew A; Poulter, Neil N; Sever, Peter P; Shields, Denis C DC; Stanton, Alice V AV; Chatterjee, Aurobindo A; Hyde, Craig C; Calle, Roberto A RA; DeMicco, David A DA; Trompet, Stella S; Postmus, Iris I; Ford, Ian I; Jukema, J Wouter JW; Caulfield, Mark M; Hitman, Graham A GA
Publication Date: 2012-05

Variant appearance in text: rs11591147
PubMed Link: 22368281
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Implications of discoveries from genome-wide association studies in current cardiovascular practice.

World Journal Of Cardiology
Jeemon, Panniyammakal P; Pettigrew, Kerry K; Sainsbury, Christopher C; Prabhakaran, Dorairaj D; Padmanabhan, Sandosh S
Publication Date: 2011-07-26

Variant appearance in text: rs11591147
PubMed Link: 21860704
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Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study.

Plos Genetics
Dumitrescu, Logan L; Carty, Cara L CL; Taylor, Kira K; Schumacher, Fredrick R FR; Hindorff, Lucia A LA; Ambite, José L JL; Anderson, Garnet G; Best, Lyle G LG; Brown-Gentry, Kristin K; Bůžková, Petra P; Carlson, Christopher S CS; Cochran, Barbara B; Cole, Shelley A SA; Devereux, Richard B RB; Duggan, Dave D; Eaton, Charles B CB; Fornage, Myriam M; Franceschini, Nora N; Haessler, Jeff J; Howard, Barbara V BV; Johnson, Karen C KC; Laston, Sandra S; Kolonel, Laurence N LN; Lee, Elisa T ET; MacCluer, Jean W JW; Manolio, Teri A TA; Pendergrass, Sarah A SA; Quibrera, Miguel M; Shohet, Ralph V RV; Wilkens, Lynne R LR; Haiman, Christopher A CA; Le Marchand, Loïc L; Buyske, Steven S; Kooperberg, Charles C; North, Kari E KE; Crawford, Dana C DC
Publication Date: 2011-06

Variant appearance in text: rs11591147
PubMed Link: 21738485
Variant Present in the following documents:
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Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.

European Journal Of Epidemiology
Janssens, A Cecile J W AC; Ioannidis, John P A JP; Bedrosian, Sara S; Boffetta, Paolo P; Dolan, Siobhan M SM; Dowling, Nicole N; Fortier, Isabel I; Freedman, Andrew N AN; Grimshaw, Jeremy M JM; Gulcher, Jeffrey J; Gwinn, Marta M; Hlatky, Mark A MA; Janes, Holly H; Kraft, Peter P; Melillo, Stephanie S; O'Donnell, Christopher J CJ; Pencina, Michael J MJ; Ransohoff, David D; Schully, Sheri D SD; Seminara, Daniela D; Winn, Deborah M DM; Wright, Caroline F CF; van Duijn, Cornelia M CM; Little, Julian J; Khoury, Muin J MJ
Publication Date: 2011-04

Variant appearance in text: rs11591147
PubMed Link: 21424820
Variant Present in the following documents:
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Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.

European Journal Of Human Genetics : Ejhg
Janssens, A Cecile J W AC; Ioannidis, John P A JP; Bedrosian, Sara S; Boffetta, Paolo P; Dolan, Siobhan M SM; Dowling, Nicole N; Fortier, Isabel I; Freedman, Andrew N AN; Grimshaw, Jeremy M JM; Gulcher, Jeffrey J; Gwinn, Marta M; Hlatky, Mark A MA; Janes, Holly H; Kraft, Peter P; Melillo, Stephanie S; O'Donnell, Christopher J CJ; Pencina, Michael J MJ; Ransohoff, David D; Schully, Sheri D SD; Seminara, Daniela D; Winn, Deborah M DM; Wright, Caroline F CF; van Duijn, Cornelia M CM; Little, Julian J; Khoury, Muin J MJ
Publication Date: 2011-05

Variant appearance in text: rs11591147
PubMed Link: 21407270
Variant Present in the following documents:
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Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review.

American Journal Of Epidemiology
Panagiotou, Orestis A OA; Evangelou, Evangelos E; Ioannidis, John P A JP
Publication Date: 2010-10-15

Variant appearance in text: rs11591147
PubMed Link: 20876667
Variant Present in the following documents:
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Using a latent growth curve model for an integrative assessment of the effects of genetic and environmental factors on multiple phenotypes.

Bmc Proceedings
Hamid, Jemila S JS; Roslin, Nicole M NM; Paterson, Andrew D AD; Beyene, Joseph J
Publication Date: 2009-12-15

Variant appearance in text: rs11591147
PubMed Link: 20018036
Variant Present in the following documents:
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Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.

Lipids In Health And Disease
Ronald, James J; Rajagopalan, Ramakrishnan R; Ranchalis, Jane E JE; Marshall, Julieann K JK; Hatsukami, Thomas S TS; Heagerty, Patrick J PJ; Jarvik, Gail P GP
Publication Date: 2009-12-01

Variant appearance in text: rs11591147
PubMed Link: 19951432
Variant Present in the following documents:
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Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

American Journal Of Human Genetics
Talmud, Philippa J PJ; Drenos, Fotios F; Shah, Sonia S; Shah, Tina T; Palmen, Jutta J; Verzilli, Claudio C; Gaunt, Tom R TR; Pallas, Jacky J; Lovering, Ruth R; Li, Kawah K; Casas, Juan Pablo JP; Sofat, Reecha R; Kumari, Meena M; Rodriguez, Santiago S; Johnson, Toby T; Newhouse, Stephen J SJ; Dominiczak, Anna A; Samani, Nilesh J NJ; Caulfield, Mark M; Sever, Peter P; Stanton, Alice A; Shields, Denis C DC; Padmanabhan, Sandosh S; Melander, Olle O; Hastie, Claire C; Delles, Christian C; Ebrahim, Shah S; Marmot, Michael G MG; Smith, George Davey GD; Lawlor, Debbie A DA; Munroe, Patricia B PB; Day, Ian N IN; Kivimaki, Mika M; Whittaker, John J; Humphries, Steve E SE; Hingorani, Aroon D AD; , ; , ; ,
Publication Date: 2009-11

Variant appearance in text: rs11591147
PubMed Link: 19913121
Variant Present in the following documents:
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