Variant ID: 1-55509213-G-A

NM_174936.3(PCSK9):c.208-303G>A

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Additive Effects of Genetic Interleukin-6 Signaling Downregulation and Low-Density Lipoprotein Cholesterol Lowering on Cardiovascular Disease: A 2×2 Factorial Mendelian Randomization Analysis.

Journal Of The American Heart Association
Georgakis, Marios K MK; Malik, Rainer R; Burgess, Stephen S; Dichgans, Martin M
Publication Date: 2021-12-20

Variant appearance in text: rs10888896
PubMed Link: 34927447
Variant Present in the following documents:
  • JAH3-11-e023277.pdf
  • JAH3-11-e023277-s001.pdf
View BVdb publication page



Genetic and In Vitro Inhibition of PCSK9 and Calcific Aortic Valve Stenosis.

Jacc. Basic To Translational Science
Perrot, Nicolas N; Valerio, Vincenza V; Moschetta, Donato D; Boekholdt, S Matthijs SM; Dina, Christian C; Chen, Hao Yu HY; Abner, Erik E; Martinsson, Andreas A; Manikpurage, Hasanga D HD; Rigade, Sidwell S; Capoulade, Romain R; Mass, Elvira E; Clavel, Marie-Annick MA; Le Tourneau, Thierry T; Messika-Zeitoun, David D; Wareham, Nicholas J NJ; Engert, James C JC; Polvani, Gianluca G; Pibarot, Philippe P; Esko, Tõnu T; Smith, J Gustav JG; Mathieu, Patrick P; Thanassoulis, George G; Schott, Jean-Jacques JJ; Bossé, Yohan Y; Camera, Marina M; Thériault, Sébastien S; Poggio, Paolo P; Arsenault, Benoit J BJ
Publication Date: 2020-07

Variant appearance in text: rs10888896
PubMed Link: 32760854
Variant Present in the following documents:
  • Main text
View BVdb publication page



Correlation of PCSK9 gene polymorphism with cerebral ischemic stroke in Xinjiang Han and Uygur populations.

Medical Science Monitor : International Medical Journal Of Experimental And Clinical Research
Han, Dengfeng D; Ma, Jianhua J; Zhang, Xiaoning X; Cai, Jian J; Li, Jinlan J; Tuerxun, Tuerhong T; Hao, Chenguang C; Du, Lei L; Lei, Jing J
Publication Date: 2014-09-30

Variant appearance in text: rs10888896
PubMed Link: 25266949
Variant Present in the following documents:
  • Main text
View BVdb publication page



Evaluation of the effect of genetic variation on the relationship between statins, cardiovascular disease and cancer.

International Journal Of Molecular Epidemiology And Genetics
Desai, Pinkal P; Jay, Allison A; Bock, Cathryn C; Dyson, Gregory G; Okwuosa, Tochukwu T; Simon, Michael S MS
Publication Date: 2013-11-28

Variant appearance in text: rs10888896
PubMed Link: 24319534
Variant Present in the following documents:
  • Main text
View BVdb publication page



PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or noncardiovascular clinical events in an elderly population.

Journal Of Lipid Research
Postmus, Iris I; Trompet, Stella S; de Craen, Anton J M AJ; Buckley, Brendan M BM; Ford, Ian I; Stott, David J DJ; Sattar, Naveed N; Slagboom, P Eline PE; Westendorp, Rudi G J RG; Jukema, J Wouter JW
Publication Date: 2013-02

Variant appearance in text: rs10888896
PubMed Link: 23300213
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic variability within the cholesterol lowering pathway and the effectiveness of statins in reducing the risk of MI.

Atherosclerosis
Peters, Bas J M BJ; Pett, Helmi H; Klungel, Olaf H OH; Stricker, Bruno H Ch BH; Psaty, Bruce M BM; Glazer, Nicole L NL; Wiggins, Kerri L KL; Bis, Josh C JC; de Boer, Anthonius A; Maitland-van der Zee, Anke-Hilse AH
Publication Date: 2011-08

Variant appearance in text: rs10888896
PubMed Link: 21741043
Variant Present in the following documents:
  • Main text
View BVdb publication page



Complexity in the genetic architecture of leukoaraiosis in hypertensive sibships from the GENOA Study.

Bmc Medical Genomics
Smith, Jennifer A JA; Turner, Stephen T ST; Sun, Yan V YV; Fornage, Myriam M; Kelly, Reagan J RJ; Mosley, Thomas H TH; Jack, Clifford R CR; Kullo, Iftikhar J IJ; Kardia, Sharon L R SL
Publication Date: 2009-04-07

Variant appearance in text: rs10888896
PubMed Link: 19351393
Variant Present in the following documents:
  • Main text
View BVdb publication page