Publications:

---

Genetic analysis of the PCSK9 locus in psychological, psychiatric, metabolic and cardiovascular traits in UK Biobank.

European Journal Of Human Genetics : Ejhg

Hay, Rachel R; Cullen, Breda B; Graham, Nicholas N; Lyall, Donald M DM; Aman, Alisha A; Pell, Jill P JP; Ward, Joey J; Smith, Daniel J DJ; Strawbridge, Rona J RJ

Publication Date: 2022-12

Variant appearance in text: rs11206514

PubMed Link: 35501368

Variant Present in the following documents:

• Main text
• 41431_2022_Article_1107.pdf

View BVdb publication page

---

Associations of genetically proxied inhibition of HMG-CoA reductase, NPC1L1, and PCSK9 with breast cancer and prostate cancer.

Breast Cancer Research : Bcr

Sun, Lulu L; Ding, Huan H; Jia, Yiming Y; Shi, Mengyao M; Guo, Daoxia D; Yang, Pinni P; Wang, Yu Y; Liu, Fanghua F; Zhang, Yonghong Y; Zhu, Zhengbao Z

Publication Date: 2022-02-12

Variant appearance in text: rs11206514

PubMed Link: 35151363

Variant Present in the following documents:

• Main text
• 13058_2022_Article_1508.pdf

View BVdb publication page

---

Associations of genetically proxied inhibition of HMG-CoA reductase, NPC1L1, and PCSK9 with breast cancer and prostate cancer.

Breast Cancer Research : Bcr

Sun, Lulu L; Ding, Huan H; Jia, Yiming Y; Shi, Mengyao M; Guo, Daoxia D; Yang, Pinni P; Wang, Yu Y; Liu, Fanghua F; Zhang, Yonghong Y; Zhu, Zhengbao Z

Publication Date: 2022-02-12

Variant appearance in text: rs11206514

PubMed Link: 35151363

Variant Present in the following documents:

• Main text
• 13058_2022_Article_1508.pdf

View BVdb publication page

---

Association Between Genetically Proxied Lipid-Lowering Drug Targets and Renal Cell Carcinoma: A Mendelian Randomization Study.

Frontiers In Nutrition

Liu, Luyang L; Sheng, Chao C; Lyu, Zhangyan Z; Dai, Hongji H; Chen, Kexin K

Publication Date: 2021

Variant appearance in text: rs11206514

PubMed Link: 34712689

Variant Present in the following documents:

• Main text
• fnut-08-755834.pdf

View BVdb publication page

---

HMG-Coenzyme A Reductase as a Drug Target for the Prevention of Ankylosing Spondylitis.

Frontiers In Cell And Developmental Biology

Zhong, Zhenyu Z; Feng, Xiaojie X; Su, Guannan G; Du, Liping L; Liao, Weiting W; Liu, Shengyun S; Li, Fuzhen F; Zuo, Xianbo X; Yang, Peizeng P

Publication Date: 2021

Variant appearance in text: rs11206514

PubMed Link: 34692687

Variant Present in the following documents:

• Main text
• fcell-09-731072.pdf

View BVdb publication page

---

Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease.

Nature Communications

Schmidt, Amand F AF; Hunt, Nicholas B NB; Gordillo-Marañón, Maria M; Charoen, Pimphen P; Drenos, Fotios F; Kivimaki, Mika M; Lawlor, Deborah A DA; Giambartolomei, Claudia C; Papacosta, Olia O; Chaturvedi, Nishi N; Bis, Joshua C JC; O'Donnell, Christopher J CJ; Wannamethee, Goya G; Wong, Andrew A; Price, Jackie F JF; Hughes, Alun D AD; Gaunt, Tom R TR; Franceschini, Nora N; Mook-Kanamori, Dennis O DO; Zwierzyna, Magdalena M; Sofat, Reecha R; Hingorani, Aroon D AD; Finan, Chris C

Publication Date: 2021-09-24

Variant appearance in text: rs11206514

PubMed Link: 34561430

Variant Present in the following documents:

• 41467_2021_25703_MOESM1_ESM.pdf

View BVdb publication page

---

Genetic drug target validation using Mendelian randomisation.

Nature Communications

Schmidt, Amand F AF; Finan, Chris C; Gordillo-Marañón, Maria M; Asselbergs, Folkert W FW; Freitag, Daniel F DF; Patel, Riyaz S RS; Tyl, Benoît B; Chopade, Sandesh S; Faraway, Rupert R; Zwierzyna, Magdalena M; Hingorani, Aroon D AD

Publication Date: 2020-06-26

Variant appearance in text: rs11206514

PubMed Link: 32591531

Variant Present in the following documents:

• 41467_2020_16969_MOESM1_ESM.pdf

View BVdb publication page

---

Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer.

Jama

Yarmolinsky, James J; Bull, Caroline J CJ; Vincent, Emma E EE; Robinson, Jamie J; Walther, Axel A; Smith, George Davey GD; Lewis, Sarah J SJ; Relton, Caroline L CL; Martin, Richard M RM

Publication Date: 2020-02-18

Variant appearance in text: rs11206514

PubMed Link: 32068819

Variant Present in the following documents:

• Main text

View BVdb publication page

---

A Mendelian randomization study of the effects of blood lipids on breast cancer risk.

Nature Communications

Nowak, Christoph C; Ärnlöv, Johan J

Publication Date: 2018-09-27

Variant appearance in text: rs11206514

PubMed Link: 30262900

Variant Present in the following documents:

• 41467_2018_6467_MOESM1_ESM.pdf

View BVdb publication page

---

Correlation of PCSK9 gene polymorphism with cerebral ischemic stroke in Xinjiang Han and Uygur populations.

Medical Science Monitor : International Medical Journal Of Experimental And Clinical Research

Han, Dengfeng D; Ma, Jianhua J; Zhang, Xiaoning X; Cai, Jian J; Li, Jinlan J; Tuerxun, Tuerhong T; Hao, Chenguang C; Du, Lei L; Lei, Jing J

Publication Date: 2014-09-30

Variant appearance in text: rs11206514

PubMed Link: 25266949

Variant Present in the following documents:

• Main text
• medscimonit-20-1758.pdf

View BVdb publication page

---

Serum cholesterol and variant in cholesterol-related gene CETP predict white matter microstructure.

Neurobiology Of Aging

Warstadt, Nicholus M NM; Dennis, Emily L EL; Jahanshad, Neda N; Kohannim, Omid O; Nir, Talia M TM; McMahon, Katie L KL; de Zubicaray, Greig I GI; Montgomery, Grant W GW; Henders, Anjali K AK; Martin, Nicholas G NG; Whitfield, John B JB; Jack, Clifford R CR; Bernstein, Matt A MA; Weiner, Michael W MW; Toga, Arthur W AW; Wright, Margaret J MJ; Thompson, Paul M PM; ,

Publication Date: 2014-11

Variant appearance in text: rs11206514

PubMed Link: 24997672

Variant Present in the following documents:

• Main text

View BVdb publication page

---

PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or noncardiovascular clinical events in an elderly population.

Journal Of Lipid Research

Postmus, Iris I; Trompet, Stella S; de Craen, Anton J M AJ; Buckley, Brendan M BM; Ford, Ian I; Stott, David J DJ; Sattar, Naveed N; Slagboom, P Eline PE; Westendorp, Rudi G J RG; Jukema, J Wouter JW

Publication Date: 2013-02

Variant appearance in text: rs11206514

PubMed Link: 23300213

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk.

Human Molecular Genetics

Drenos, Fotios F; Talmud, Philippa J PJ; Casas, Juan P JP; Smeeth, Liam L; Palmen, Jutta J; Humphries, Steve E SE; Hingorani, Aroon D AD

Publication Date: 2009-06-15

Variant appearance in text: rs11206514

PubMed Link: 19336475

Variant Present in the following documents:

• ddp159_1.pdf

View BVdb publication page

---