Variant ID: 1-55518007-CG-GC

NM_174936.3(PCSK9):c.580_581delinsGC;(p.R194A)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Emerging Insights on the Diverse Roles of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) in Chronic Liver Diseases: Cholesterol Metabolism and Beyond.

International Journal Of Molecular Sciences
Grewal, Thomas T; Buechler, Christa C
Publication Date: 2022-01-19

Variant appearance in text: PCSK9: R194A
PubMed Link: 35162992
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Systematic Approach to Assess the Activity and Classification of PCSK9 Variants.

International Journal Of Molecular Sciences
Uribe, Kepa B KB; Chemello, Kevin K; Larrea-Sebal, Asier A; Benito-Vicente, Asier A; Galicia-Garcia, Unai U; Bourane, Steeve S; Jaafar, Ali K AK; Lambert, Gilles G; Martín, César C
Publication Date: 2021-12-18

Variant appearance in text: PCSK9: R194A
PubMed Link: 34948399
Variant Present in the following documents:
  • Main text
  • ijms-22-13602.pdf
View BVdb publication page



Treatment-Induced Viral Cure of Hepatitis C Virus-Infected Patients Involves a Dynamic Interplay among three Important Molecular Players in Lipid Homeostasis: Circulating microRNA (miR)-24, miR-223, and Proprotein Convertase Subtilisin/Kexin Type 9.

Ebiomedicine
Hyrina, Anastasia A; Olmstead, Andrea D AD; Steven, Paul P; Krajden, Mel M; Tam, Edward E; Jean, François F
Publication Date: 2017-09

Variant appearance in text: PCSK9: R194A
PubMed Link: 28864162
Variant Present in the following documents:
  • Main text
View BVdb publication page



Plasma Membrane Tetraspanin CD81 Complexes with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR), and Its Levels Are Reduced by PCSK9.

The Journal Of Biological Chemistry
Le, Quoc-Tuan QT; Blanchet, Matthieu M; Seidah, Nabil G NG; Labonté, Patrick P
Publication Date: 2015-09-18

Variant appearance in text: PCSK9: R194A
PubMed Link: 26195630
Variant Present in the following documents:
  • Main text
View BVdb publication page



Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor.

The Journal Of Biological Chemistry
Zhang, Yingnan Y; Eigenbrot, Charles C; Zhou, Lijuan L; Shia, Steven S; Li, Wei W; Quan, Clifford C; Tom, Jeffrey J; Moran, Paul P; Di Lello, Paola P; Skelton, Nicholas J NJ; Kong-Beltran, Monica M; Peterson, Andrew A; Kirchhofer, Daniel D
Publication Date: 2014-01-10

Variant appearance in text: PCSK9: R194A
PubMed Link: 24225950
Variant Present in the following documents:
  • Main text
View BVdb publication page