A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans.
Genetics
Coste, Alix A; Turner, Vincent V; Ischer, Françoise F; Morschhäuser, Joachim J; Forche, Anja A; Selmecki, Anna A; Berman, Judith J; Bille, Jacques J; Sanglard, Dominique D