Publications:

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Associations of genetically proxied inhibition of HMG-CoA reductase, NPC1L1, and PCSK9 with breast cancer and prostate cancer.

Breast Cancer Research : Bcr

Sun, Lulu L; Ding, Huan H; Jia, Yiming Y; Shi, Mengyao M; Guo, Daoxia D; Yang, Pinni P; Wang, Yu Y; Liu, Fanghua F; Zhang, Yonghong Y; Zhu, Zhengbao Z

Publication Date: 2022-02-12

Variant appearance in text: rs585131

PubMed Link: 35151363

Variant Present in the following documents:

• Main text
• 13058_2022_Article_1508.pdf

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Additive Effects of Genetic Interleukin-6 Signaling Downregulation and Low-Density Lipoprotein Cholesterol Lowering on Cardiovascular Disease: A 2×2 Factorial Mendelian Randomization Analysis.

Journal Of The American Heart Association

Georgakis, Marios K MK; Malik, Rainer R; Burgess, Stephen S; Dichgans, Martin M

Publication Date: 2021-12-20

Variant appearance in text: rs585131

PubMed Link: 34927447

Variant Present in the following documents:

• JAH3-11-e023277.pdf
• JAH3-11-e023277-s001.pdf

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Association Between Genetically Proxied Lipid-Lowering Drug Targets and Renal Cell Carcinoma: A Mendelian Randomization Study.

Frontiers In Nutrition

Liu, Luyang L; Sheng, Chao C; Lyu, Zhangyan Z; Dai, Hongji H; Chen, Kexin K

Publication Date: 2021

Variant appearance in text: rs585131

PubMed Link: 34712689

Variant Present in the following documents:

• Main text
• fnut-08-755834.pdf

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HMG-Coenzyme A Reductase as a Drug Target for the Prevention of Ankylosing Spondylitis.

Frontiers In Cell And Developmental Biology

Zhong, Zhenyu Z; Feng, Xiaojie X; Su, Guannan G; Du, Liping L; Liao, Weiting W; Liu, Shengyun S; Li, Fuzhen F; Zuo, Xianbo X; Yang, Peizeng P

Publication Date: 2021

Variant appearance in text: rs585131

PubMed Link: 34692687

Variant Present in the following documents:

• Main text
• fcell-09-731072.pdf

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Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease.

Nature Communications

Schmidt, Amand F AF; Hunt, Nicholas B NB; Gordillo-Marañón, Maria M; Charoen, Pimphen P; Drenos, Fotios F; Kivimaki, Mika M; Lawlor, Deborah A DA; Giambartolomei, Claudia C; Papacosta, Olia O; Chaturvedi, Nishi N; Bis, Joshua C JC; O'Donnell, Christopher J CJ; Wannamethee, Goya G; Wong, Andrew A; Price, Jackie F JF; Hughes, Alun D AD; Gaunt, Tom R TR; Franceschini, Nora N; Mook-Kanamori, Dennis O DO; Zwierzyna, Magdalena M; Sofat, Reecha R; Hingorani, Aroon D AD; Finan, Chris C

Publication Date: 2021-09-24

Variant appearance in text: rs585131

PubMed Link: 34561430

Variant Present in the following documents:

• 41467_2021_25703_MOESM1_ESM.pdf

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Genetic and In Vitro Inhibition of PCSK9 and Calcific Aortic Valve Stenosis.

Jacc. Basic To Translational Science

Perrot, Nicolas N; Valerio, Vincenza V; Moschetta, Donato D; Boekholdt, S Matthijs SM; Dina, Christian C; Chen, Hao Yu HY; Abner, Erik E; Martinsson, Andreas A; Manikpurage, Hasanga D HD; Rigade, Sidwell S; Capoulade, Romain R; Mass, Elvira E; Clavel, Marie-Annick MA; Le Tourneau, Thierry T; Messika-Zeitoun, David D; Wareham, Nicholas J NJ; Engert, James C JC; Polvani, Gianluca G; Pibarot, Philippe P; Esko, Tõnu T; Smith, J Gustav JG; Mathieu, Patrick P; Thanassoulis, George G; Schott, Jean-Jacques JJ; Bossé, Yohan Y; Camera, Marina M; Thériault, Sébastien S; Poggio, Paolo P; Arsenault, Benoit J BJ

Publication Date: 2020-07

Variant appearance in text: rs585131

PubMed Link: 32760854

Variant Present in the following documents:

• Main text

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Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer.

Jama

Yarmolinsky, James J; Bull, Caroline J CJ; Vincent, Emma E EE; Robinson, Jamie J; Walther, Axel A; Smith, George Davey GD; Lewis, Sarah J SJ; Relton, Caroline L CL; Martin, Richard M RM

Publication Date: 2020-02-18

Variant appearance in text: rs585131

PubMed Link: 32068819

Variant Present in the following documents:

• Main text

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Integrative mutation, haplotype and G × G interaction evidence connects ABGL4, LRP8 and PCSK9 genes to cardiometabolic risk.

Scientific Reports

Guo, Tao T; Yin, Rui-Xing RX; Yao, Li-Mei LM; Huang, Feng F; Pan, Ling L; Lin, Wei-Xiong WX; Yang, De-Zhai DZ; Pan, Shang-Ling SL

Publication Date: 2016-11-17

Variant appearance in text: rs585131

PubMed Link: 27853278

Variant Present in the following documents:

• Main text

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Molecular population genetics of PCSK9: a signature of recent positive selection.

Pharmacogenetics And Genomics

Ding, Keyue K; Kullo, Iftikhar J IJ

Publication Date: 2008-03

Variant appearance in text: rs585131

PubMed Link: 18300938

Variant Present in the following documents:

• Main text

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