Publications:

Unexpected structures formed by the kinase RET C634R mutant extracellular domain suggest potential oncogenic mechanisms in MEN2A.

The Journal Of Biological Chemistry

Liu, Yixin Y; De Castro Ribeiro, Orquidea O; Haapanen, Outi O; Craven, Gregory B GB; Sharma, Vivek V; Muench, Stephen P SP; Goldman, Adrian A

Publication Date: 2022-10

Variant appearance in text: RET: C216S

PubMed Link: 35985422

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing.

Structure (London, England : 1993)

Adams, Sarah E SE; Purkiss, Andrew G AG; Knowles, Phillip P PP; Nans, Andrea A; Briggs, David C DC; Borg, Annabel A; Earl, Christopher P CP; Goodman, Kerry M KM; Nawrotek, Agata A; Borg, Aaron J AJ; McIntosh, Pauline B PB; Houghton, Francesca M FM; Kjær, Svend S; McDonald, Neil Q NQ

Publication Date: 2021-07-01

Variant appearance in text: RET: C216S

PubMed Link: 33484636

Variant Present in the following documents:

• mmc1.pdf
• mmc2.pdf

View BVdb publication page