RET c.2213T>C ;(p.V738A)

Variant ID: 10-43612108-T-C

NM_020975.4(RET):c.2213T>C;(p.V738A)

This variant was identified in 15 publications

View GRCh38 version.




Publications:


RET Proto-Oncogene-Not Such an Obvious Starting Point in Cancer Therapy.

Cancers
Kucharczyk, Tomasz T; Krawczyk, Paweł P; Kowalski, Dariusz M DM; Płużański, Adam A; Kubiatowski, Tomasz T; Kalinka, Ewa E
Publication Date: 2022-10-27

Variant appearance in text: RET: V738A
PubMed Link: 36358717
Variant Present in the following documents:
  • Main text
  • cancers-14-05298.pdf
View BVdb publication page



Precision oncology for RET-related tumors.

Frontiers In Oncology
Verrienti, Antonella A; Grani, Giorgio G; Sponziello, Marialuisa M; Pecce, Valeria V; Damante, Giuseppe G; Durante, Cosimo C; Russo, Diego D; Filetti, Sebastiano S
Publication Date: 2022

Variant appearance in text: RET: V738A
PubMed Link: 36091144
Variant Present in the following documents:
  • Main text
  • fonc-12-992636.pdf
View BVdb publication page



RET kinase inhibitors for RET-altered thyroid cancers.

Therapeutic Advances In Medical Oncology
Vodopivec, Danica M DM; Hu, Mimi I MI
Publication Date: 2022

Variant appearance in text: RET: V738A
PubMed Link: 35756966
Variant Present in the following documents:
  • 10.1177_17588359221101691.pdf
View BVdb publication page



The Role of the Kinase Inhibitors in Thyroid Cancers.

Pharmaceutics
Cuomo, Francesca F; Giani, Claudio C; Cobellis, Gilda G
Publication Date: 2022-05-11

Variant appearance in text: RET: V738A
PubMed Link: 35631627
Variant Present in the following documents:
  • Main text
  • pharmaceutics-14-01040.pdf
View BVdb publication page



Sporadic Medullary Thyroid Carcinoma: Towards a Precision Medicine.

Frontiers In Endocrinology
Matrone, Antonio A; Gambale, Carla C; Prete, Alessandro A; Elisei, Rossella R
Publication Date: 2022

Variant appearance in text: RET: V738A
PubMed Link: 35422765
Variant Present in the following documents:
  • Main text
  • fendo-13-864253.pdf
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Designing Novel Compounds for the Treatment and Management of RET-Positive Non-Small Cell Lung Cancer-Fragment Based Drug Design Strategy.

Molecules (Basel, Switzerland)
Ramesh, Priyanka P; Veerappapillai, Shanthi S
Publication Date: 2022-02-28

Variant appearance in text: RET: V738A
PubMed Link: 35268691
Variant Present in the following documents:
  • Main text
  • molecules-27-01590.pdf
View BVdb publication page



[Advances in the Treatment of RET Fusion-Positive Advanced Non-Small-Cell Lung Cancer].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Gao, Qingyun Q; Su, Junwei J; Xiao, Faman F; Lin, Xiaocheng X; Yang, Jinji J
Publication Date: 2021-11-08

Variant appearance in text: RET: V738A
PubMed Link: 34743497
Variant Present in the following documents:
  • Main text
View BVdb publication page



[Advances in the Treatment of RET Fusion-positive Advanced Non-small Cell Lung Cancer].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Gao, Qingyun Q; Su, Junwei J; Xiao, Faman F; Lin, Xiaocheng X; Yang, Jinji J
Publication Date: 2021-12-20

Variant appearance in text: RET: V738A
PubMed Link: 34743497
Variant Present in the following documents:
  • Main text
View BVdb publication page



Hallmarks of RET and Co-occuring Genomic Alterations in RET-aberrant Cancers.

Molecular Cancer Therapeutics
Adashek, Jacob J JJ; Desai, Aakash P AP; Andreev-Drakhlin, Alexander Y AY; Roszik, Jason J; Cote, Gilbert J GJ; Subbiah, Vivek V
Publication Date: 2021-10

Variant appearance in text: RET: V738A
PubMed Link: 34493590
Variant Present in the following documents:
  • Main text
  • 1769.pdf
View BVdb publication page



Precision therapy for RET-altered cancers with RET inhibitors.

Trends In Cancer
Thein, Kyaw Z KZ; Velcheti, Vamsidhar V; Mooers, Blaine H M BHM; Wu, Jie J; Subbiah, Vivek V
Publication Date: 2021-12

Variant appearance in text: RET: V738A
PubMed Link: 34391699
Variant Present in the following documents:
  • Main text
View BVdb publication page



Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases.

Scientific Reports
Moccia, Marialuisa M; Yang, Donglin D; Lakkaniga, Naga Rajiv NR; Frett, Brendan B; McConnell, Nicholas N; Zhang, Lingtian L; Brescia, Annalisa A; Federico, Giorgia G; Zhang, Lingzhi L; Salerno, Paolo P; Santoro, Massimo M; Li, Hong-Yu HY; Carlomagno, Francesca F
Publication Date: 2021-08-09

Variant appearance in text: RET: V738A
PubMed Link: 34373541
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_95612.pdf
View BVdb publication page



The L730V/I RET roof mutations display different activities toward pralsetinib and selpercatinib.

Npj Precision Oncology
Shen, Tao T; Hu, Xueqing X; Liu, Xuan X; Subbiah, Vivek V; Mooers, Blaine H M BHM; Wu, Jie J
Publication Date: 2021-06-07

Variant appearance in text: RET: V738A
PubMed Link: 34099825
Variant Present in the following documents:
  • Main text
  • 41698_2021_Article_188.pdf
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Chasing the Target: New Phenomena of Resistance to Novel Selective RET Inhibitors in Lung Cancer. Updated Evidence and Future Perspectives.

Cancers
Fancelli, Sara S; Caliman, Enrico E; Mazzoni, Francesca F; Brugia, Marco M; Castiglione, Francesca F; Voltolini, Luca L; Pillozzi, Serena S; Antonuzzo, Lorenzo L
Publication Date: 2021-03-04

Variant appearance in text: RET: V738A
PubMed Link: 33806299
Variant Present in the following documents:
  • Main text
  • cancers-13-01091.pdf
View BVdb publication page



Structural basis of acquired resistance to selpercatinib and pralsetinib mediated by non-gatekeeper RET mutations.

Annals Of Oncology : Official Journal Of The European Society For Medical Oncology
Subbiah, V V; Shen, T T; Terzyan, S S SS; Liu, X X; Hu, X X; Patel, K P KP; Hu, M M; Cabanillas, M M; Behrang, A A; Meric-Bernstam, F F; Vo, P T T PTT; Mooers, B H M BHM; Wu, J J
Publication Date: 2021-02

Variant appearance in text: RET: V738A
PubMed Link: 33161056
Variant Present in the following documents:
  • Main text
  • nihms-1668692.pdf
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Refinement of evolutionary medicine predictions based on clinical evidence for the manifestations of Mendelian diseases.

Scientific Reports
Šimčíková, Daniela D; Heneberg, Petr P
Publication Date: 2019-12-09

Variant appearance in text: RET: V738A
PubMed Link: 31819097
Variant Present in the following documents:
  • 41598_2019_54976_MOESM2_ESM.xlsx, sheet 8
View BVdb publication page



Drug resistance profiles of mutations in the RET kinase domain.

British Journal Of Pharmacology
Liu, Xuan X; Shen, Tao T; Mooers, Blaine H M BHM; Hilberg, Frank F; Wu, Jie J
Publication Date: 2018-09

Variant appearance in text: RET: V738A
PubMed Link: 29908090
Variant Present in the following documents:
  • Main text
View BVdb publication page