RET c.2428G>C ;(p.G810R)

Variant ID: 10-43615014-G-C

NM_020975.4(RET):c.2428G>C;(p.G810R)

This variant was identified in 28 publications

View GRCh38 version.




Publications:


RET signaling in breast cancer therapeutic resistance and metastasis.

Breast Cancer Research : Bcr
Pecar, Geoffrey G; Liu, Simeng S; Hooda, Jagmohan J; Atkinson, Jennifer M JM; Oesterreich, Steffi S; Lee, Adrian V AV
Publication Date: 2023-03-14

Variant appearance in text: RET: G810R
PubMed Link: 36918928
Variant Present in the following documents:
  • Main text
  • 13058_2023_Article_1622.pdf
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Recent progress in targeted therapy for non-small cell lung cancer.

Frontiers In Pharmacology
Xiao, Yanxia Y; Liu, Pu P; Wei, Jie J; Zhang, Xin X; Guo, Jun J; Lin, Yajun Y
Publication Date: 2023

Variant appearance in text: RET: G810R
PubMed Link: 36909198
Variant Present in the following documents:
  • Main text
  • fphar-14-1125547.pdf
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A comprehensive overview of the relationship between RET gene and tumor occurrence.

Frontiers In Oncology
Zhao, Lu L; Wang, Na N; Zhang, Dou D; Jia, Yingjie Y; Kong, Fanming F
Publication Date: 2023

Variant appearance in text: RET: G810R
PubMed Link: 36865807
Variant Present in the following documents:
  • Main text
  • fonc-13-1090757.pdf
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Advances in the Diagnosis and Treatment of a Driving Target: RET Rearrangements in non-Small-Cell Lung Cancer (NSCLC) Especially in China.

Technology In Cancer Research & Treatment
Li, Tao T; Yang, Wen-Yu WY; Liu, Ting-Ting TT; Li, Yao Y; Liu, Lu L; Zheng, Xuan X; Zhao, Lei L; Zhang, Fan F; Hu, Yi Y
Publication Date: 2023

Variant appearance in text: RET: G810R
PubMed Link: 36628459
Variant Present in the following documents:
  • Main text
  • 10.1177_15330338221148802.pdf
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Targeted therapy of RET fusion-positive non-small cell lung cancer.

Frontiers In Oncology
Shen, Zixiong Z; Qiu, Binxu B; Li, Lin L; Yang, Bo B; Li, Guanghu G
Publication Date: 2022

Variant appearance in text: RET: G810R
PubMed Link: 36582799
Variant Present in the following documents:
  • Main text
  • fonc-12-1033484.pdf
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Precious Gene: The Application of RET-Altered Inhibitors.

Molecules (Basel, Switzerland)
Gou, Qitao Q; Gan, Xiaochuan X; Li, Longhao L; Gou, Qiheng Q; Zhang, Tao T
Publication Date: 2022-12-13

Variant appearance in text: RET: G810R
PubMed Link: 36557971
Variant Present in the following documents:
  • Main text
  • molecules-27-08839.pdf
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Design of new drugs for medullary thyroid carcinoma.

Frontiers In Oncology
Li, Yanqing Y; Luo, Ziyu Z; Wang, Xinxing X; Zhang, Songtao S; Hei, Hu H; Qin, Jianwu J
Publication Date: 2022

Variant appearance in text: RET: G810R
PubMed Link: 36544713
Variant Present in the following documents:
  • Main text
  • fonc-12-993725.pdf
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RET signaling pathway and RET inhibitors in human cancer.

Frontiers In Oncology
Regua, Angelina T AT; Najjar, Mariana M; Lo, Hui-Wen HW
Publication Date: 2022

Variant appearance in text: RET: G810R
PubMed Link: 35957881
Variant Present in the following documents:
  • Main text
  • fonc-12-932353.pdf
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Applications of Liquid Biopsies in Non-Small-Cell Lung Cancer.

Diagnostics (Basel, Switzerland)
Pesta, Martin M; Shetti, Dattatrya D; Kulda, Vlastimil V; Knizkova, Tereza T; Houfkova, Katerina K; Bagheri, Mahyar Sharif MS; Svaton, Martin M; Polivka, Jiri J
Publication Date: 2022-07-25

Variant appearance in text: RET: G810R
PubMed Link: 35892510
Variant Present in the following documents:
  • Main text
  • diagnostics-12-01799.pdf
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AACR Project GENIE: 100,000 Cases and Beyond.

Cancer Discovery
Pugh, Trevor J TJ; Bell, Jonathan L JL; Bruce, Jeff P JP; Doherty, Gary J GJ; Galvin, Matthew M; Green, Michelle F MF; Hunter-Zinck, Haley H; Kumari, Priti P; Lenoue-Newton, Michele L ML; Li, Marilyn M MM; Lindsay, James J; Mazor, Tali T; Ovalle, Andrea A; Sammut, Stephen-John SJ; Schultz, Nikolaus N; Yu, Thomas V TV; Sweeney, Shawn M SM; Bernard, Brady B; ,
Publication Date: 2022-09-02

Variant appearance in text: RET: G810R
PubMed Link: 35819403
Variant Present in the following documents:
  • cd-21-1547_supplementary_table_1_suppst1.xlsx, sheet 1
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Designing Novel Compounds for the Treatment and Management of RET-Positive Non-Small Cell Lung Cancer-Fragment Based Drug Design Strategy.

Molecules (Basel, Switzerland)
Ramesh, Priyanka P; Veerappapillai, Shanthi S
Publication Date: 2022-02-28

Variant appearance in text: RET: G810R
PubMed Link: 35268691
Variant Present in the following documents:
  • Main text
  • molecules-27-01590.pdf
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New approaches for patients with advanced radioiodine-refractory thyroid cancer.

World Journal Of Clinical Oncology
Pitoia, Fabián F; Jerkovich, Fernando F; Trimboli, Pierpaolo P; Smulever, Anabella A
Publication Date: 2022-01-24

Variant appearance in text: RET: G810R
PubMed Link: 35116229
Variant Present in the following documents:
  • Main text
  • WJCO-13-9.pdf
View BVdb publication page



Emerging Biomarkers in Thyroid Practice and Research.

Cancers
Agarwal, Shipra S; Bychkov, Andrey A; Jung, Chan-Kwon CK
Publication Date: 2021-12-31

Variant appearance in text: RET: G810R
PubMed Link: 35008368
Variant Present in the following documents:
  • Main text
View BVdb publication page



Emerging Biomarkers in Thyroid Practice and Research.

Cancers
Agarwal, Shipra S; Bychkov, Andrey A; Jung, Chan-Kwon CK
Publication Date: 2021-12-31

Variant appearance in text: RET: G810R
PubMed Link: 35008368
Variant Present in the following documents:
  • Main text
View BVdb publication page



Utility of the Ba/F3 cell system for exploring on-target mechanisms of resistance to targeted therapies for lung cancer.

Cancer Science
Koga, Takamasa T; Suda, Kenichi K; Mitsudomi, Tetsuya T
Publication Date: 2022-03

Variant appearance in text: RET: G810R
PubMed Link: 34997674
Variant Present in the following documents:
  • Main text
  • CAS-113-815.pdf
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Discovery of a Potent Candidate for RET-Specific Non-Small-Cell Lung Cancer-A Combined In Silico and In Vitro Strategy.

Pharmaceutics
Ramesh, Priyanka P; Shin, Woong-Hee WH; Veerappapillai, Shanthi S
Publication Date: 2021-10-24

Variant appearance in text: RET: G810R
PubMed Link: 34834190
Variant Present in the following documents:
  • Main text
  • pharmaceutics-13-01775.pdf
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RET Fusion: Joining the Ranks of Targetable Molecular Drivers in NSCLC.

Jto Clinical And Research Reports
Osta, Badi El BE; Ramalingam, Suresh S SS
Publication Date: 2020-09

Variant appearance in text: RET: G810R
PubMed Link: 34589946
Variant Present in the following documents:
  • Main text
  • main.pdf
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Hallmarks of RET and Co-occuring Genomic Alterations in RET-aberrant Cancers.

Molecular Cancer Therapeutics
Adashek, Jacob J JJ; Desai, Aakash P AP; Andreev-Drakhlin, Alexander Y AY; Roszik, Jason J; Cote, Gilbert J GJ; Subbiah, Vivek V
Publication Date: 2021-10

Variant appearance in text: RET: G810R
PubMed Link: 34493590
Variant Present in the following documents:
  • Main text
  • 1769.pdf
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Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases.

Scientific Reports
Moccia, Marialuisa M; Yang, Donglin D; Lakkaniga, Naga Rajiv NR; Frett, Brendan B; McConnell, Nicholas N; Zhang, Lingtian L; Brescia, Annalisa A; Federico, Giorgia G; Zhang, Lingzhi L; Salerno, Paolo P; Santoro, Massimo M; Li, Hong-Yu HY; Carlomagno, Francesca F
Publication Date: 2021-08-09

Variant appearance in text: RET: G810R
PubMed Link: 34373541
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_95612.pdf
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[Research Progress of Fusion Genes RET in Non-small Cell Lung Cancer].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Zheng, Yujun Y; Jiang, Wei W; Chen, Dongyan D; Li, Yanjun Y; Dai, Lulu L; Huang, Lei L; Wang, Mingji M
Publication Date: 2021-08-20

Variant appearance in text: RET: G810R
PubMed Link: 34120433
Variant Present in the following documents:
  • Main text
  • zgfazz-24-8-591.pdf
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Chasing the Target: New Phenomena of Resistance to Novel Selective RET Inhibitors in Lung Cancer. Updated Evidence and Future Perspectives.

Cancers
Fancelli, Sara S; Caliman, Enrico E; Mazzoni, Francesca F; Brugia, Marco M; Castiglione, Francesca F; Voltolini, Luca L; Pillozzi, Serena S; Antonuzzo, Lorenzo L
Publication Date: 2021-03-04

Variant appearance in text: RET: G810R
PubMed Link: 33806299
Variant Present in the following documents:
  • Main text
View BVdb publication page



Therapeutic strategies in RET gene rearranged non-small cell lung cancer.

Journal Of Hematology & Oncology
Drusbosky, Leylah M LM; Rodriguez, Estelamari E; Dawar, Richa R; Ikpeazu, Chukwuemeka V CV
Publication Date: 2021-03-26

Variant appearance in text: RET: G810R
PubMed Link: 33771190
Variant Present in the following documents:
  • Main text
  • 13045_2021_Article_1063.pdf
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Decade in review: a new era for RET-rearranged lung cancers.

Translational Lung Cancer Research
Choudhury, Noura J NJ; Drilon, Alexander A
Publication Date: 2020-12

Variant appearance in text: RET: G810R
PubMed Link: 33489819
Variant Present in the following documents:
  • Main text
  • tlcr-09-06-2571.pdf
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Structural basis of acquired resistance to selpercatinib and pralsetinib mediated by non-gatekeeper RET mutations.

Annals Of Oncology : Official Journal Of The European Society For Medical Oncology
Subbiah, V V; Shen, T T; Terzyan, S S SS; Liu, X X; Hu, X X; Patel, K P KP; Hu, M M; Cabanillas, M M; Behrang, A A; Meric-Bernstam, F F; Vo, P T T PTT; Mooers, B H M BHM; Wu, J J
Publication Date: 2021-02

Variant appearance in text: RET: G810R
PubMed Link: 33161056
Variant Present in the following documents:
  • Main text
View BVdb publication page



Advances in Targeting RET-Dependent Cancers.

Cancer Discovery
Subbiah, Vivek V; Cote, Gilbert J GJ
Publication Date: 2020-04

Variant appearance in text: RET: G810R
PubMed Link: 32094155
Variant Present in the following documents:
  • Main text
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State-of-the-Art Strategies for Targeting RET-Dependent Cancers.

Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology
Subbiah, Vivek V; Yang, Dong D; Velcheti, Vamsidhar V; Drilon, Alexander A; Meric-Bernstam, Funda F
Publication Date: 2020-04-10

Variant appearance in text: RET: G810R
PubMed Link: 32083997
Variant Present in the following documents:
  • Main text
View BVdb publication page



RET Solvent Front Mutations Mediate Acquired Resistance to Selective RET Inhibition in RET-Driven Malignancies.

Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer
Solomon, Benjamin J BJ; Tan, Lavinia L; Lin, Jessica J JJ; Wong, Stephen Q SQ; Hollizeck, Sebastian S; Ebata, Kevin K; Tuch, Brian B BB; Yoda, Satoshi S; Gainor, Justin F JF; Sequist, Lecia V LV; Oxnard, Geoffrey R GR; Gautschi, Oliver O; Drilon, Alexander A; Subbiah, Vivek V; Khoo, Christine C; Zhu, Edward Y EY; Nguyen, Michele M; Henry, Dahlia D; Condroski, Kevin R KR; Kolakowski, Gabrielle R GR; Gomez, Eliana E; Ballard, Joshua J; Metcalf, Andrew T AT; Blake, James F JF; Dawson, Sarah-Jane SJ; Blosser, Wayne W; Stancato, Louis F LF; Brandhuber, Barbara J BJ; Andrews, Steve S; Robinson, Bruce G BG; Rothenberg, S Michael SM
Publication Date: 2020-04

Variant appearance in text: RET: G810R
PubMed Link: 31988000
Variant Present in the following documents:
  • Main text
  • nihms-1616172.pdf
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Refinement of evolutionary medicine predictions based on clinical evidence for the manifestations of Mendelian diseases.

Scientific Reports
Šimčíková, Daniela D; Heneberg, Petr P
Publication Date: 2019-12-09

Variant appearance in text: RET: G810R
PubMed Link: 31819097
Variant Present in the following documents:
  • 41598_2019_54976_MOESM2_ESM.xlsx, sheet 8
View BVdb publication page



Targeting RET-driven cancers: lessons from evolving preclinical and clinical landscapes.

Nature Reviews. Clinical Oncology
Drilon, Alexander A; Hu, Zishuo I ZI; Lai, Gillianne G Y GGY; Tan, Daniel S W DSW
Publication Date: 2018-03

Variant appearance in text: RET: G810R
PubMed Link: 29134959
Variant Present in the following documents:
  • Main text
View BVdb publication page