Identification of a key residue mediating bone morphogenetic protein (BMP)-6 resistance to noggin inhibition allows for engineered BMPs with superior agonist activity.
The Journal Of Biological Chemistry
Song, Kening K; Krause, Carola C; Shi, Songting S; Patterson, Marilyn M; Suto, Robert R; Grgurevic, Lovorka L; Vukicevic, Slobodan S; van Dinther, Maarten M; Falb, Dean D; Ten Dijke, Peter P; Alaoui-Ismaili, Moulay Hicham MH