Publications:

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CRISPR Technologies in Chinese Hamster Ovary Cell Line Engineering.

International Journal Of Molecular Sciences

Glinšek, Katja K; Bozovičar, Krištof K; Bratkovič, Tomaž T

Publication Date: 2023-05-02

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PubMed Link: 37175850

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Examination of the Functional Relationship between PD-L1 DNA Methylation and mRNA Expression in Non-Small-Cell Lung Cancer.

Cancers

Larsen, Trine V TV; Dybdal, Nina N; Daugaard, Tina F TF; Lade-Keller, Johanne J; Lin, Lin L; Sorensen, Boe S BS; Nielsen, Anders L AL

Publication Date: 2023-03-22

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PubMed Link: 36980795

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• cancers-15-01909.pdf

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Recent Progress and Future Prospect of CRISPR/Cas-Derived Transcription Activation (CRISPRa) System in Plants.

Cells

Ding, Xiao X; Yu, Lu L; Chen, Luo L; Li, Yujie Y; Zhang, Jinlun J; Sheng, Hanyan H; Ren, Zhengwei Z; Li, Yunlong Y; Yu, Xiaohan X; Jin, Shuangxia S; Cao, Jinglin J

Publication Date: 2022-09-28

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PubMed Link: 36231007

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CRISPR/Cas9 system in breast cancer therapy: advancement, limitations and future scope.

Cancer Cell International

Karn, Vamika V; Sandhya, Sandhya S; Hsu, Wayne W; Parashar, Deepak D; Singh, Himanshu Narayan HN; Jha, Niraj Kumar NK; Gupta, Saurabh S; Dubey, Navneet Kumar NK; Kumar, Sanjay S

Publication Date: 2022-07-25

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PubMed Link: 35879772

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• 12935_2022_Article_2654.pdf

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CRISPR based therapeutics: a new paradigm in cancer precision medicine.

Molecular Cancer

Das, Sumit S; Bano, Shehnaz S; Kapse, Prachi P; Kundu, Gopal C GC

Publication Date: 2022-03-25

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PubMed Link: 35337340

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• 12943_2022_Article_1552.pdf

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Deciphering Plant Chromatin Regulation via CRISPR/dCas9-Based Epigenome Engineering.

Epigenomes

Dubois, Annick A; Roudier, François F

Publication Date: 2021-08-24

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PubMed Link: 34968366

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• epigenomes-05-00017.pdf

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Unraveling the functional role of DNA demethylation at specific promoters by targeted steric blockage of DNA methyltransferase with CRISPR/dCas9.

Nature Communications

Sapozhnikov, Daniel M DM; Szyf, Moshe M

Publication Date: 2021-09-29

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PubMed Link: 34588447

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• 41467_2021_25991_MOESM2_ESM.pdf
• 41467_2021_Article_25991.pdf

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Unraveling the functional role of DNA demethylation at specific promoters by targeted steric blockage of DNA methyltransferase with CRISPR/dCas9.

Nature Communications

Sapozhnikov, Daniel M DM; Szyf, Moshe M

Publication Date: 2021-09-29

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PubMed Link: 34588447

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TALENs-an indispensable tool in the era of CRISPR: a mini review.

Journal, Genetic Engineering & Biotechnology

Bhardwaj, Anuradha A; Nain, Vikrant V

Publication Date: 2021-08-21

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PubMed Link: 34420096

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• 43141_2021_Article_225.pdf

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Genome engineering and disease modeling via programmable nucleases for insulin gene therapy; promises of CRISPR/Cas9 technology.

World Journal Of Stem Cells

Eksi, Yunus E YE; Sanlioglu, Ahter D AD; Akkaya, Bahar B; Ozturk, Bilge Esin BE; Sanlioglu, Salih S

Publication Date: 2021-06-26

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PubMed Link: 34249224

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• WJSC-13-485.pdf

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Reprogramming the anti-tumor immune response via CRISPR genetic and epigenetic editing.

Molecular Therapy. Methods & Clinical Development

Alves, Eric E; Taifour, Shahama S; Dolcetti, Riccardo R; Chee, Jonathan J; Nowak, Anna K AK; Gaudieri, Silvana S; Blancafort, Pilar P

Publication Date: 2021-06-11

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PubMed Link: 34095343

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CRISPR-based tools for plant genome engineering.

Emerging Topics In Life Sciences

Volpi E Silva, Nathalia N; Patron, Nicola J NJ

Publication Date: 2017-11-10

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PubMed Link: 33525768

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• ETLS-1-135.pdf

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Epigenome engineering: new technologies for precision medicine.

Nucleic Acids Research

Sgro, Agustin A; Blancafort, Pilar P

Publication Date: 2020-12-16

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PubMed Link: 33196851

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Gene-Editing Technologies Paired With Viral Vectors for Translational Research Into Neurodegenerative Diseases.

Frontiers In Molecular Neuroscience

Rittiner, Joseph Edward JE; Moncalvo, Malik M; Chiba-Falek, Ornit O; Kantor, Boris B

Publication Date: 2020

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PubMed Link: 32903507

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• fnmol-13-00148.pdf

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Applying gene-editing technology to elucidate the functional consequence of genetic and epigenetic variation in Alzheimer's disease.

Brain Pathology (Zurich, Switzerland)

Schrauben, Michael M; Dempster, Emma E; Lunnon, Katie K

Publication Date: 2020-09

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PubMed Link: 32654206

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Therapeutic Editing of the TP53 Gene: Is CRISPR/Cas9 an Option?

Genes

Mirgayazova, Regina R; Khadiullina, Raniya R; Chasov, Vitaly V; Mingaleeva, Rimma R; Miftakhova, Regina R; Rizvanov, Albert A; Bulatov, Emil E

Publication Date: 2020-06-25

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PubMed Link: 32630614

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Innovative Precision Gene-Editing Tools in Personalized Cancer Medicine.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)

Dai, Xiaofeng X; Blancafort, Pilar P; Wang, Peiyu P; Sgro, Agustin A; Thompson, Erik W EW; Ostrikov, Kostya Ken KK

Publication Date: 2020-06

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PubMed Link: 32596104

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• ADVS-7-1902552.pdf

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CRISPR/Cas Derivatives as Novel Gene Modulating Tools: Possibilities and In Vivo Applications.

International Journal Of Molecular Sciences

Xu, Xingbo X; Hulshoff, Melanie S MS; Tan, Xiaoying X; Zeisberg, Michael M; Zeisberg, Elisabeth M EM

Publication Date: 2020-04-25

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PubMed Link: 32344896

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Gene editing and CRISPR in the clinic: current and future perspectives.

Bioscience Reports

Hirakawa, Matthew P MP; Krishnakumar, Raga R; Timlin, Jerilyn A JA; Carney, James P JP; Butler, Kimberly S KS

Publication Date: 2020-04-30

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PubMed Link: 32207531

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• bsr-40-bsr20200127.pdf

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Applications of the CRISPR/Cas system beyond gene editing.

Biology Methods & Protocols

Anton, Tobias T; Karg, Elisabeth E; Bultmann, Sebastian S

Publication Date: 2018

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PubMed Link: 32161796

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Locus-specific DNA methylation of Mecp2 promoter leads to autism-like phenotypes in mice.

Cell Death & Disease

Lu, Zongyang Z; Liu, Zhen Z; Mao, Wei W; Wang, Xinying X; Zheng, Xiaoguo X; Chen, Shanshan S; Cao, Beibei B; Huang, Shisheng S; Zhang, Xuliang X; Zhou, Tao T; Zhang, Yu Y; Huang, Xingxu X; Sun, Qiang Q; Li, Jia-Da JD

Publication Date: 2020-02-03

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PubMed Link: 32015323

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• 41419_2020_Article_2290.pdf

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Epigenetic Regulation of Excitatory Amino Acid Transporter 2 in Neurological Disorders.

Frontiers In Pharmacology

Alam, Mohammad Afaque MA; Datta, Prasun K PK

Publication Date: 2019

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PubMed Link: 31920679

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Dead Cas Systems: Types, Principles, and Applications.

International Journal Of Molecular Sciences

Brezgin, Sergey S; Kostyusheva, Anastasiya A; Kostyushev, Dmitry D; Chulanov, Vladimir V

Publication Date: 2019-11-30

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PubMed Link: 31801211

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Recent advances in the CRISPR genome editing tool set.

Experimental & Molecular Medicine

Moon, Su Bin SB; Kim, Do Yon DY; Ko, Jeong-Heon JH; Kim, Yong-Sam YS

Publication Date: 2019-11-05

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PubMed Link: 31685795

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• 12276_2019_Article_339.pdf

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Regulation of gene expression by altered promoter methylation using a CRISPR/Cas9-mediated epigenetic editing system.

Scientific Reports

Kang, Jeong Gu JG; Park, Jin Suk JS; Ko, Jeong-Heosn JH; Kim, Yong-Sam YS

Publication Date: 2019-08-19

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PubMed Link: 31427598

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• 41598_2019_Article_48130.pdf

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The next generation of CRISPR-Cas technologies and applications.

Nature Reviews. Molecular Cell Biology

Pickar-Oliver, Adrian A; Gersbach, Charles A CA

Publication Date: 2019-08

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PubMed Link: 31147612

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Reprogrammable CRISPR/dCas9-based recruitment of DNMT1 for site-specific DNA demethylation and gene regulation.

Cell Discovery

Lu, Anrui A; Wang, Jingman J; Sun, Weihong W; Huang, Weiren W; Cai, Zhiming Z; Zhao, Guoping G; Wang, Jin J

Publication Date: 2019

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PubMed Link: 31016028

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• 41421_2019_90_MOESM1_ESM.pdf

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In vivo epigenome editing and transcriptional modulation using CRISPR technology.

Transgenic Research

Lau, Cia-Hin CH; Suh, Yousin Y

Publication Date: 2018-12

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PubMed Link: 30284145

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High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis.

Nature Communications

Xu, Xingbo X; Tan, Xiaoying X; Tampe, Björn B; Wilhelmi, Tim T; Hulshoff, Melanie S MS; Saito, Shoji S; Moser, Tobias T; Kalluri, Raghu R; Hasenfuss, Gerd G; Zeisberg, Elisabeth M EM; Zeisberg, Michael M

Publication Date: 2018-08-29

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PubMed Link: 30158531

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• 41467_2018_Article_5766.pdf

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A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs.

Genome Research

Pflueger, Christian C; Tan, Dennis D; Swain, Tessa T; Nguyen, Trung T; Pflueger, Jahnvi J; Nefzger, Christian C; Polo, Jose M JM; Ford, Ethan E; Lister, Ryan R

Publication Date: 2018-08

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PubMed Link: 29907613

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• 1193.pdf

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The CRISPR tool kit for genome editing and beyond.

Nature Communications

Adli, Mazhar M

Publication Date: 2018-05-15

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PubMed Link: 29765029

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• 41467_2018_Article_4252.pdf

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Epigenetic editing: How cutting-edge targeted epigenetic modification might provide novel avenues for autoimmune disease therapy.

Clinical Immunology (Orlando, Fla.)

Jeffries, Matlock A MA

Publication Date: 2018-11

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PubMed Link: 29421443

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dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression.

Nucleic Acids Research

O'Geen, Henriette H; Ren, Chonghua C; Nicolet, Charles M CM; Perez, Andrew A AA; Halmai, Julian J; Le, Victoria M VM; Mackay, Joel P JP; Farnham, Peggy J PJ; Segal, David J DJ

Publication Date: 2017-09-29

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PubMed Link: 28973434

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• gkx578.pdf

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Stabilization of Foxp3 expression by CRISPR-dCas9-based epigenome editing in mouse primary T cells.

Epigenetics & Chromatin

Okada, Masahiro M; Kanamori, Mitsuhiro M; Someya, Kazue K; Nakatsukasa, Hiroko H; Yoshimura, Akihiko A

Publication Date: 2017

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PubMed Link: 28503202

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• 13072_2017_Article_129.pdf

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Editing the genome of hiPSC with CRISPR/Cas9: disease models.

Mammalian Genome : Official Journal Of The International Mammalian Genome Society

Bassett, Andrew R AR

Publication Date: 2017-08

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PubMed Link: 28303292

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CRISPR-Mediated Epigenome Editing.

The Yale Journal Of Biology And Medicine

Enríquez, Paul P

Publication Date: 2016-12

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PubMed Link: 28018139

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• yjbm_89_4_471.pdf

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Genome and Epigenome Editing in Mechanistic Studies of Human Aging and Aging-Related Disease.

Gerontology

Lau, Cia-Hin CH; Suh, Yousin Y

Publication Date: 2017

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PubMed Link: 27974723

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Genome-Editing Technologies: Principles and Applications.

Cold Spring Harbor Perspectives In Biology

Gaj, Thomas T; Sirk, Shannon J SJ; Shui, Sai-Lan SL; Liu, Jia J

Publication Date: 2016-12-01

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PubMed Link: 27908936

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Applications of Engineered DNA-Binding Molecules Such as TAL Proteins and the CRISPR/Cas System in Biology Research.

International Journal Of Molecular Sciences

Fujita, Toshitsugu T; Fujii, Hodaka H

Publication Date: 2015-09-24

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PubMed Link: 26404236

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• ijms-16-23143.pdf

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