Publications:

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Systematic assessment of prognostic molecular features across cancers.

Cell Genomics

Santhanam, Balaji B; Oikonomou, Panos P; Tavazoie, Saeed S

Publication Date: 2023-03-08

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PubMed Link: 36950380

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• mmc2.pdf

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Prognostic and diagnostic values of non-coding RNAs as biomarkers for breast cancer: An umbrella review and pan-cancer analysis.

Frontiers In Molecular Biosciences

Bahramy, Afshin A; Zafari, Narges N; Rajabi, Fatemeh F; Aghakhani, Amirhossein A; Jayedi, Ahmad A; Khaboushan, Alireza Soltani AS; Zolbin, Masoumeh Majidi MM; Yekaninejad, Mir Saeed MS

Publication Date: 2023

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PubMed Link: 36726376

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• fmolb-10-1096524.pdf

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Downregulation of UBE4B promotes CNS axon regrowth and functional recovery after stroke.

Iscience

Jin, Shuang S; Chen, Xiangfeng X; Zheng, Hanyu H; Cai, Wanxiong W; Lin, Xurong X; Kong, Xiangxing X; Ni, Yingchun Y; Ye, Jingjia J; Li, Xiaodan X; Shen, Luoan L; Guo, Binjie B; Abdelrahman, Zeinab Z; Zhou, Songlin S; Mao, Susu S; Wang, Yaxian Y; Yao, Chun C; Gu, Xiaosong X; Yu, Bin B; Wang, Zhiping Z; Wang, Xuhua X

Publication Date: 2023-01-20

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PubMed Link: 36654858

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• main.pdf

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A compendium of co-regulated mitoribosomal proteins in pan-cancer uncovers collateral defective events in tumor malignancy.

Iscience

Chang, Ching-Wen CW; Wei, Zhuang Z; Durell, Stewart R SR; Ma, Lichun L; Forgues, Marshonna M; Wang, Xin Wei XW

Publication Date: 2022-10-21

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PubMed Link: 36274950

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RPRM negatively regulates ATM levels through its nuclear translocation on irradiation mediated by CDK4/6 and IPO11.

Iscience

Zhang, Yarui Y; Ou, Guomin G; Ye, Zhujing Z; Zhou, Zhou Z; Cao, Qianlin Q; Li, Mengting M; Wang, Jingdong J; Cao, Jianping J; Yang, Hongying H

Publication Date: 2022-10-21

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PubMed Link: 36185355

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• main.pdf

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Different Inhibition of Nrf2 by Two Keap1 Isoforms α and β to Shape Malignant Behaviour of Human Hepatocellular Carcinoma.

International Journal Of Molecular Sciences

Chen, Feilong F; Xiao, Mei M; Feng, Jing J; Wufur, Reziyamu R; Liu, Keli K; Hu, Shaofan S; Zhang, Yiguo Y

Publication Date: 2022-09-07

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PubMed Link: 36142252

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• Main text
• ijms-23-10342.pdf

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Characterization of aging cancer-associated fibroblasts draws implications in prognosis and immunotherapy response in low-grade gliomas.

Frontiers In Genetics

Zhou, Zijian Z; Wei, Jinhong J; Kuang, Lijun L; Zhang, Ke K; Liu, Yini Y; He, Zhongming Z; Li, Luo L; Lu, Bin B

Publication Date: 2022

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PubMed Link: 36092895

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• Main text
• fgene-13-897083.pdf

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Integrated Bioinformatics Analysis of Serine Racemase as an Independent Prognostic Biomarker in Endometrial Cancer.

Frontiers In Genetics

Cui, Zhiwei Z; Mo, Jiantao J; Wang, Lijun L; Wang, Rongli R; Cheng, Feiyan F; Wang, Lihui L; Yang, Xinyuan X; Wang, Wei W

Publication Date: 2022

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PubMed Link: 35923695

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• Main text

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Lighting a Fire: Gasdermin-Mediated Pyroptosis Remodels the Glioma Microenvironment and Promotes Immune Checkpoint Blockade Response.

Frontiers In Immunology

Cai, Yonghua Y; Li, Ke K; Lin, Jie J; Liang, Xianqiu X; Xu, Wei W; Zhan, Zhengming Z; Xue, Shuaishuai S; Zeng, Yu Y; Chai, Peng P; Mao, Yangqi Y; Song, Zibin Z; Han, Lei L; Song, Ye Y; Zhang, Xian X; Wang, Hai H

Publication Date: 2022

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PubMed Link: 35784306

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• Main text
• fimmu-13-910490.pdf

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Phasing analysis of lung cancer genomes using a long read sequencer.

Nature Communications

Sakamoto, Yoshitaka Y; Miyake, Shuhei S; Oka, Miho M; Kanai, Akinori A; Kawai, Yosuke Y; Nagasawa, Satoi S; Shiraishi, Yuichi Y; Tokunaga, Katsushi K; Kohno, Takashi T; Seki, Masahide M; Suzuki, Yutaka Y; Suzuki, Ayako A

Publication Date: 2022-06-16

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PubMed Link: 35710642

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• 41467_2022_31133_MOESM2_ESM.pdf

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RSK1 promotes mammalian axon regeneration by inducing the synthesis of regeneration-related proteins.

Plos Biology

Mao, Susu S; Chen, Yuanyuan Y; Feng, Wei W; Zhou, Songlin S; Jiang, Chunyi C; Zhang, Junjie J; Liu, Xiaohong X; Qian, Tianmei T; Liu, Kai K; Wang, Yaxian Y; Yao, Chun C; Gu, Xiaosong X; Yu, Bin B

Publication Date: 2022-06

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PubMed Link: 35648763

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• Main text
• pbio.3001653.pdf

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Extracellular vesicles enriched with an endothelial cell pro-survival microRNA affects skin tissue regeneration.

Molecular Therapy. Nucleic Acids

Fernandes, Hugo H; Zonnari, Alessandra A; Abreu, Ricardo R; Aday, Sezin S; Barão, Marta M; Albino, Inês I; Lino, Miguel M; Branco, Ana A; Seabra, Cátia C; Barata, Tânia T; Leal, Ermelindo C EC; Tralhão, José Guilherme JG; Gonçalves, Lino L; de Jong, Alwin A; Peters, Hendrika A B HAB; de Vries, Margreet R MR; da Costa Martins, Paula P; Quax, Paul H A PHA; Ferreira, Lino L

Publication Date: 2022-06-14

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PubMed Link: 35474734

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• mmc4.pdf
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Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C.

Cancer Discovery

Weiss, Andreas A; Lorthiois, Edwige E; Barys, Louise L; Beyer, Kim S KS; Bomio-Confaglia, Claudio C; Burks, Heather H; Chen, Xueying X; Cui, Xiaoming X; de Kanter, Ruben R; Dharmarajan, Lekshmi L; Fedele, Carmine C; Gerspacher, Marc M; Guthy, Daniel Alexander DA; Head, Victoria V; Jaeger, Ashley A; Núñez, Eloísa Jiménez EJ; Kearns, Jeffrey D JD; Leblanc, Catherine C; Maira, Sauveur-Michel SM; Murphy, Jason J; Oakman, Helen H; Ostermann, Nils N; Ottl, Johannes J; Rigollier, Pascal P; Roman, Danielle D; Schnell, Christian C; Sedrani, Richard R; Shimizu, Toshio T; Stringer, Rowan R; Vaupel, Andrea A; Voshol, Hans H; Wessels, Peter P; Widmer, Toni T; Wilcken, Rainer R; Xu, Kun K; Zecri, Frederic F; Farago, Anna F AF; Cotesta, Simona S; Brachmann, Saskia M SM

Publication Date: 2022-06-02

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PubMed Link: 35404998

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• Main text
• 1500.pdf

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Dysregulation of interaction between LOXhigh fibroblast and smooth muscle cells contributes to the pathogenesis of aortic dissection.

Theranostics

Chen, Yinan Y; Zhang, Tao T; Yao, Fang F; Gao, Xiang X; Li, Dandan D; Fu, Shufang S; Mao, Lin L; Liu, Fei F; Zhang, Xuelin X; Xu, Yongle Y; Deng, Jianqing J; Li, Weihao W; Fan, Guangpu G; Xiao, Cangsong C; Chen, Yu Y; Wang, Li L; Guo, Wei W; Zhou, Bingying B

Publication Date: 2022

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PubMed Link: 34976220

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• thnov12p0910.pdf

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Reprogrammed transsulfuration promotes basal-like breast tumor progression via realigning cellular cysteine persulfidation.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Erdélyi, Katalin K; Ditrói, Tamás T; Johansson, Henrik J HJ; Czikora, Ágnes Á; Balog, Noémi N; Silwal-Pandit, Laxmi L; Ida, Tomoaki T; Olasz, Judit J; Hajdú, Dorottya D; Mátrai, Zoltán Z; Csuka, Orsolya O; Uchida, Koji K; Tóvári, József J; Engebraten, Olav O; Akaike, Takaaki T; Børresen Dale, Anne-Lise AL; Kásler, Miklós M; Lehtiö, Janne J; Nagy, Péter P

Publication Date: 2021-11-09

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PubMed Link: 34737229

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• pnas.202100050.pdf

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Pan-cancer analysis combined with experiments predicts CTHRC1 as a therapeutic target for human cancers.

Cancer Cell International

Peng, Dazhao D; Wei, Cheng C; Zhang, Xiaoyang X; Li, Shenghui S; Liang, Hao H; Zheng, Xingyu X; Jiang, Shulong S; Han, Lei L

Publication Date: 2021-10-26

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PubMed Link: 34702252

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• Main text
• 12935_2021_Article_2266.pdf

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Genomic evidence suggests that cutaneous neuroendocrine carcinomas can arise from squamous dysplastic precursors.

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc

Harms, Paul W PW; Verhaegen, Monique E ME; Hu, Kevin K; Hrycaj, Steven M SM; Chan, May P MP; Liu, Chia-Jen CJ; Grachtchouk, Marina M; Patel, Rajiv M RM; Udager, Aaron M AM; Dlugosz, Andrzej A AA

Publication Date: 2022-04

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PubMed Link: 34593967

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• Main text
• nihms-1739265.pdf

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Itraconazole inhibits nuclear delivery of extracellular vesicle cargo by disrupting the entry of late endosomes into the nucleoplasmic reticulum.

Journal Of Extracellular Vesicles

Santos, Mark F MF; Rappa, Germana G; Karbanová, Jana J; Fontana, Simona S; Bella, Maria Antonietta Di MAD; Pope, Marshall R MR; Parrino, Barbara B; Cascioferro, Stella Maria SM; Vistoli, Giulio G; Diana, Patrizia P; Cirrincione, Girolamo G; Arena, Goffredo O GO; Woo, Gyunghwi G; Huang, Kevin K; Huynh, Tony T; Moschetti, Marta M; Alessandro, Riccardo R; Corbeil, Denis D; Lorico, Aurelio A

Publication Date: 2021-08

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PubMed Link: 34429859

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Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression.

Plos Genetics

Aiderus, Aziz A; Newberg, Justin Y JY; Guzman-Rojas, Liliana L; Contreras-Sandoval, Ana M AM; Meshey, Amanda L AL; Jones, Devin J DJ; Amaya-Manzanares, Felipe F; Rangel, Roberto R; Ward, Jerrold M JM; Lee, Song-Choon SC; Ban, Kenneth Hon-Kim KH; Rogers, Keith K; Rogers, Susan M SM; Selvanesan, Luxmanan L; McNoe, Leslie A LA; Copeland, Neal G NG; Jenkins, Nancy A NA; Tsai, Kenneth Y KY; Black, Michael A MA; Mann, Karen M KM; Mann, Michael B MB

Publication Date: 2021-08

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PubMed Link: 34398873

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• Main text
• pgen.1009094.pdf

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Single-cell atlas reveals meningeal leukocyte heterogeneity in the developing mouse brain.

Genes & Development

Zelco, Aura A; Börjesson, Vanja V; de Kanter, Jurrian K JK; Lebrero-Fernandez, Cristina C; Lauschke, Volker M VM; Rocha-Ferreira, Eridan E; Nilsson, Gisela G; Nair, Syam S; Svedin, Pernilla P; Bemark, Mats M; Hagberg, Henrik H; Mallard, Carina C; Holstege, Frank C P FCP; Wang, Xiaoyang X

Publication Date: 2021-08-01

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PubMed Link: 34301765

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• Main text

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Single-cell atlas reveals meningeal leukocyte heterogeneity in the developing mouse brain.

Genes & Development

Zelco, Aura A; Börjesson, Vanja V; de Kanter, Jurrian K JK; Lebrero-Fernandez, Cristina C; Lauschke, Volker M VM; Rocha-Ferreira, Eridan E; Nilsson, Gisela G; Nair, Syam S; Svedin, Pernilla P; Bemark, Mats M; Hagberg, Henrik H; Mallard, Carina C; Holstege, Frank C P FCP; Wang, Xiaoyang X

Publication Date: 2021-08-01

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PubMed Link: 34301765

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Recent developments in the treatment of small cell lung cancer.

European Respiratory Review : An Official Journal Of The European Respiratory Society

Hiddinga, Birgitta I BI; Raskin, Jo J; Janssens, Annelies A; Pauwels, Patrick P; Van Meerbeeck, Jan P JP

Publication Date: 2021-09-30

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PubMed Link: 34261744

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Pten Regulates Cardiomyocyte Differentiation by Modulating Non-CG Methylation via Dnmt3.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)

Wang, Wuming W; Lu, Gang G; Liu, Hong-Bin HB; Xiong, Zhiqiang Z; Leung, Ho-Duen HD; Cao, Ruican R; Pang, Alan Lap-Yin AL; Su, Xianwei X; Law, Patrick Wai Nok PWN; Zhao, Zhiju Z; Chen, Zi-Jiang ZJ; Chan, Wai-Yee WY

Publication Date: 2021-09

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PubMed Link: 34247447

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• Main text
• ADVS-8-2100849.pdf

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A smart multiantenna gene theranostic system based on the programmed assembly of hypoxia-related siRNAs.

Nature Communications

Gong, Xue X; Wang, Haizhou H; Li, Ruomeng R; Tan, Kaiyue K; Wei, Jie J; Wang, Jing J; Hong, Chen C; Shang, Jinhua J; Liu, Xiaoqing X; Liu, Jing J; Wang, Fuan F

Publication Date: 2021-06-25

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PubMed Link: 34172725

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• 41467_2021_24191_MOESM2_ESM.pdf

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The Predictive Value of Monocytes in Immune Microenvironment and Prognosis of Glioma Patients Based on Machine Learning.

Frontiers In Immunology

Zhang, Nan N; Dai, Ziyu Z; Wu, Wantao W; Wang, Zeyu Z; Cao, Hui H; Zhang, Yakun Y; Wang, Zhanchao Z; Zhang, Hao H; Cheng, Quan Q

Publication Date: 2021

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PubMed Link: 33959130

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PDIA5 is Correlated With Immune Infiltration and Predicts Poor Prognosis in Gliomas.

Frontiers In Immunology

Zhang, Hao H; He, Jialin J; Dai, Ziyu Z; Wang, Zeyu Z; Liang, Xisong X; He, Fengqiong F; Xia, Zhiwei Z; Feng, Songshan S; Cao, Hui H; Zhang, Liyang L; Cheng, Quan Q

Publication Date: 2021

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PubMed Link: 33664747

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SUMOylation of YTHDF2 promotes mRNA degradation and cancer progression by increasing its binding affinity with m6A-modified mRNAs.

Nucleic Acids Research

Hou, Guofang G; Zhao, Xian X; Li, Lian L; Yang, Qianqian Q; Liu, Xiaojia X; Huang, Caihu C; Lu, Runhui R; Chen, Ran R; Wang, Yanli Y; Jiang, Bin B; Yu, Jianxiu J

Publication Date: 2021-03-18

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PubMed Link: 33577677

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• gkab065.pdf

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Transneuronal delivery of hyper-interleukin-6 enables functional recovery after severe spinal cord injury in mice.

Nature Communications

Leibinger, Marco M; Zeitler, Charlotte C; Gobrecht, Philipp P; Andreadaki, Anastasia A; Gisselmann, Günter G; Fischer, Dietmar D

Publication Date: 2021-01-15

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PubMed Link: 33452250

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• Main text
• 41467_2020_Article_20112.pdf

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Targeting the histone demethylase PHF8-mediated PKCα-Src-PTEN axis in HER2-negative gastric cancer.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Tseng, Lin-Lu LL; Cheng, Hsin-Hung HH; Yeh, Ta-Sen TS; Huang, Shih-Chiang SC; Syu, Ya-Yun YY; Chuu, Chih-Pin CP; Yuh, Chiou-Hwa CH; Kung, Hsing-Jien HJ; Wang, Wen-Ching WC

Publication Date: 2020-10-06

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PubMed Link: 32958674

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• pnas.201919766.pdf

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Most Commonly Mutated Genes in High-Grade Serous Ovarian Carcinoma Are Nonessential for Ovarian Surface Epithelial Stem Cell Transformation.

Cell Reports

Yamulla, Robert Joseph RJ; Nalubola, Shreya S; Flesken-Nikitin, Andrea A; Nikitin, Alexander Yu AY; Schimenti, John C JC

Publication Date: 2020-09-01

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PubMed Link: 32877668

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Somatic Tissue Engineering in Mouse Models Reveals an Actionable Role for WNT Pathway Alterations in Prostate Cancer Metastasis.

Cancer Discovery

Leibold, Josef J; Ruscetti, Marcus M; Cao, Zhen Z; Ho, Yu-Jui YJ; Baslan, Timour T; Zou, Min M; Abida, Wassim W; Feucht, Judith J; Han, Teng T; Barriga, Francisco M FM; Tsanov, Kaloyan M KM; Zamechek, Leah L; Kulick, Amanda A; Amor, Corina C; Tian, Sha S; Rybczyk, Katarzyna K; Salgado, Nelson R NR; Sánchez-Rivera, Francisco J FJ; Watson, Philip A PA; de Stanchina, Elisa E; Wilkinson, John E JE; Dow, Lukas E LE; Abate-Shen, Cory C; Sawyers, Charles L CL; Lowe, Scott W SW

Publication Date: 2020-07

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PubMed Link: 32376773

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Multiplex Stimulated Raman Scattering Imaging Cytometry Reveals Lipid-Rich Protrusions in Cancer Cells under Stress Condition.

Iscience

Huang, Kai-Chih KC; Li, Junjie J; Zhang, Chi C; Tan, Yuying Y; Cheng, Ji-Xin JX

Publication Date: 2020-03-27

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PubMed Link: 32179477

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• main.pdf

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Glioblastoma cells vampirize WNT from neurons and trigger a JNK/MMP signaling loop that enhances glioblastoma progression and neurodegeneration.

Plos Biology

Portela, Marta M; Venkataramani, Varun V; Fahey-Lozano, Natasha N; Seco, Esther E; Losada-Perez, Maria M; Winkler, Frank F; Casas-Tintó, Sergio S

Publication Date: 2019-12

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PubMed Link: 31846454

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Human retinal ganglion cell axon regeneration by recapitulating developmental mechanisms: effects of recruitment of the mTOR pathway.

Development (Cambridge, England)

Teotia, Pooja P; Van Hook, Matthew J MJ; Fischer, Dietmar D; Ahmad, Iqbal I

Publication Date: 2019-07-04

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PubMed Link: 31273087

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Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway.

Science (New York, N.Y.)

Lee, Yu-Ru YR; Chen, Ming M; Lee, Jonathan D JD; Zhang, Jinfang J; Lin, Shu-Yu SY; Fu, Tian-Min TM; Chen, Hao H; Ishikawa, Tomoki T; Chiang, Shang-Yin SY; Katon, Jesse J; Zhang, Yang Y; Shulga, Yulia V YV; Bester, Assaf C AC; Fung, Jacqueline J; Monteleone, Emanuele E; Wan, Lixin L; Shen, Chen C; Hsu, Chih-Hung CH; Papa, Antonella A; Clohessy, John G JG; Teruya-Feldstein, Julie J; Jain, Suresh S; Wu, Hao H; Matesic, Lydia L; Chen, Ruey-Hwa RH; Wei, Wenyi W; Pandolfi, Pier Paolo PP

Publication Date: 2019-05-17

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PubMed Link: 31097636

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MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression.

Nature Communications

Jiang, Yao Y; Zhang, Yanqiong Y; Leung, Janet Y JY; Fan, Cheng C; Popov, Konstantin I KI; Su, Siyuan S; Qian, Jiayi J; Wang, Xiaodong X; Holtzhausen, Alisha A; Ubil, Eric E; Xiang, Yang Y; Davis, Ian I; Dokholyan, Nikolay V NV; Wu, Gang G; Perou, Charles M CM; Kim, William Y WY; Earp, H Shelton HS; Liu, Pengda P

Publication Date: 2019-04-03

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PubMed Link: 30944303

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• 41467_2019_9233_MOESM1_ESM.pdf

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Programming of macrophages by UV-irradiated apoptotic cancer cells inhibits cancer progression and lung metastasis.

Cellular & Molecular Immunology

Kim, Yong-Bae YB; Ahn, Young-Ho YH; Jung, Ji-Hae JH; Lee, Ye-Ji YJ; Lee, Jin-Hwa JH; Kang, Jihee Lee JL

Publication Date: 2019-11

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PubMed Link: 30842627

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B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells.

Oncogene

Zhou, Hongyu H; Yu, Chunlei C; Kong, Lingmei L; Xu, Xiaoliang X; Yan, Juming J; Li, Yingchao Y; An, Tao T; Gong, Liang L; Gong, Yaxiao Y; Zhu, Huifang H; Zhang, Hongbin H; Yang, Xiaodong X; Li, Yan Y

Publication Date: 2019-05

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PubMed Link: 30635656

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CellMinerCDB for Integrative Cross-Database Genomics and Pharmacogenomics Analyses of Cancer Cell Lines.

Iscience

Rajapakse, Vinodh N VN; Luna, Augustin A; Yamade, Mihoko M; Loman, Lisa L; Varma, Sudhir S; Sunshine, Margot M; Iorio, Francesco F; Sousa, Fabricio G FG; Elloumi, Fathi F; Aladjem, Mirit I MI; Thomas, Anish A; Sander, Chris C; Kohn, Kurt W KW; Benes, Cyril H CH; Garnett, Mathew M; Reinhold, William C WC; Pommier, Yves Y

Publication Date: 2018-12-21

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PubMed Link: 30553813

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• main.pdf

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p53 Maintains Baseline Expression of Multiple Tumor Suppressor Genes.

Molecular Cancer Research : Mcr

Pappas, Kyrie K; Xu, Jia J; Zairis, Sakellarios S; Resnick-Silverman, Lois L; Abate, Francesco F; Steinbach, Nicole N; Ozturk, Sait S; Saal, Lao H LH; Su, Tao T; Cheung, Pamela P; Schmidt, Hank H; Aaronson, Stuart S; Hibshoosh, Hanina H; Manfredi, James J; Rabadan, Raul R; Parsons, Ramon R

Publication Date: 2017-08

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PubMed Link: 28483946

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Amplification of USP13 drives ovarian cancer metabolism.

Nature Communications

Han, Cecil C; Yang, Lifeng L; Choi, Hyun Ho HH; Baddour, Joelle J; Achreja, Abhinav A; Liu, Yunhua Y; Li, Yujing Y; Li, Jiada J; Wan, Guohui G; Huang, Cheng C; Ji, Guang G; Zhang, Xinna X; Nagrath, Deepak D; Lu, Xiongbin X

Publication Date: 2016-11-28

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PubMed Link: 27892457

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• ncomms13525-s2.pdf

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Integration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle gene regulatory networks.

Nucleic Acids Research

Fischer, Martin M; Grossmann, Patrick P; Padi, Megha M; DeCaprio, James A JA

Publication Date: 2016-07-27

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PubMed Link: 27280975

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• gkw523.pdf

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A chemical-genetic interaction map of small molecules using high-throughput imaging in cancer cells.

Molecular Systems Biology

Breinig, Marco M; Klein, Felix A FA; Huber, Wolfgang W; Boutros, Michael M

Publication Date: 2015-12-23

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PubMed Link: 26700849

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• MSB-11-846-s007.pdf

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Phosphatase and Tensin Homolog Is a Growth Repressor of Both Rhizoid and Gametophore Development in the Moss Physcomitrella patens.

Plant Physiology

Saavedra, Laura L; Catarino, Rita R; Heinz, Tobias T; Heilmann, Ingo I; Bezanilla, Magdalena M; Malhó, Rui R

Publication Date: 2015-12

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PubMed Link: 26463087

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Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy.

Cancer Immunology Research

Holtzhausen, Alisha A; Zhao, Fei F; Evans, Kathy S KS; Tsutsui, Masahito M; Orabona, Ciriana C; Tyler, Douglas S DS; Hanks, Brent A BA

Publication Date: 2015-09

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PubMed Link: 26041736

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BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Wang, Tao T; Xiao, Min M; Ge, Yingbin Y; Krepler, Clemens C; Belser, Eric E; Lopez-Coral, Alfonso A; Xu, Xiaowei X; Zhang, Gao G; Azuma, Rikka R; Liu, Qin Q; Liu, Rui R; Li, Ling L; Amaravadi, Ravi K RK; Xu, Wei W; Karakousis, Giorgos G; Gangadhar, Tara C TC; Schuchter, Lynn M LM; Lieu, Melissa M; Khare, Sanika S; Halloran, Molly B MB; Herlyn, Meenhard M; Kaufman, Russel E RE

Publication Date: 2015-04-01

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PubMed Link: 25617424

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Integrated genomic characterization of papillary thyroid carcinoma.

Cell

,

Publication Date: 2014-10-23

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PubMed Link: 25417114

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Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth.

Cell Research

Yin, Yuan Y; Cai, Xing X; Chen, Xi X; Liang, Hongwei H; Zhang, Yujing Y; Li, Jing J; Wang, Zuoyun Z; Chen, Xiulan X; Zhang, Wen W; Yokoyama, Seiji S; Wang, Cheng C; Li, Liang L; Li, Limin L; Hou, Dongxia D; Dong, Lei L; Xu, Tao T; Hiroi, Takachika T; Yang, Fuquan F; Ji, Hongbin H; Zhang, Junfeng J; Zen, Ke K; Zhang, Chen-Yu CY

Publication Date: 2014-10

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PubMed Link: 25223704

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Arrestins function in cAR1 GPCR-mediated signaling and cAR1 internalization in the development of Dictyostelium discoideum.

Molecular Biology Of The Cell

Cao, Xiumei X; Yan, Jianshe J; Shu, Shi S; Brzostowski, Joseph A JA; Jin, Tian T

Publication Date: 2014-10-15

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PubMed Link: 25143405

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Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.

Science Signaling

Kusne, Yael Y; Carrera-Silva, Eugenio A EA; Perry, Anthony S AS; Rushing, Elisabeth J EJ; Mandell, Edward K EK; Dietrich, Justin D JD; Errasti, Andrea E AE; Gibbs, Daniel D; Berens, Michael E ME; Loftus, Joseph C JC; Hulme, Christopher C; Yang, Weiwei W; Lu, Zhimin Z; Aldape, Kenneth K; Sanai, Nader N; Rothlin, Carla V CV; Ghosh, Sourav S

Publication Date: 2014-08-12

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PubMed Link: 25118327

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A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.

Molecular Systems Biology

Vizeacoumar, Franco J FJ; Arnold, Roland R; Vizeacoumar, Frederick S FS; Chandrashekhar, Megha M; Buzina, Alla A; Young, Jordan T F JT; Kwan, Julian H M JH; Sayad, Azin A; Mero, Patricia P; Lawo, Steffen S; Tanaka, Hiromasa H; Brown, Kevin R KR; Baryshnikova, Anastasia A; Mak, Anthony B AB; Fedyshyn, Yaroslav Y; Wang, Yadong Y; Brito, Glauber C GC; Kasimer, Dahlia D; Makhnevych, Taras T; Ketela, Troy T; Datti, Alessandro A; Babu, Mohan M; Emili, Andrew A; Pelletier, Laurence L; Wrana, Jeff J; Wainberg, Zev Z; Kim, Philip M PM; Rottapel, Robert R; O'Brien, Catherine A CA; Andrews, Brenda B; Boone, Charles C; Moffat, Jason J

Publication Date: 2013-10-08

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PubMed Link: 24104479

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Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria.

Science (New York, N.Y.)

Ibrahim, Mohamed X MX; Sayin, Volkan I VI; Akula, Murali K MK; Liu, Meng M; Fong, Loren G LG; Young, Stephen G SG; Bergo, Martin O MO

Publication Date: 2013-06-14

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PubMed Link: 23686339

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Pten deletion causes mTorc1-dependent ectopic neuroblast differentiation without causing uniform migration defects.

Development (Cambridge, England)

Zhu, Guo G; Chow, Lionel M L LM; Bayazitov, Ildar T IT; Tong, Yiai Y; Gilbertson, Richard J RJ; Zakharenko, Stanislav S SS; Solecki, David J DJ; Baker, Suzanne J SJ

Publication Date: 2012-09

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PubMed Link: 22874917

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