PTEN c.29G>A ;(p.S10N)

Variant ID: 10-89624255-G-A

NM_000314.4(PTEN):c.29G>A;(p.S10N)

This variant was identified in 26 publications

View GRCh38 version.




Publications:


Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age.

Nature Communications
Burkhardt, Birgit B; Michgehl, Ulf U; Rohde, Jonas J; Erdmann, Tabea T; Berning, Philipp P; Reutter, Katrin K; Rohde, Marius M; Borkhardt, Arndt A; Burmeister, Thomas T; Dave, Sandeep S; Tzankov, Alexandar A; Dugas, Martin M; Sandmann, Sarah S; Fend, Falko F; Finger, Jasmin J; Mueller, Stephanie S; Gökbuget, Nicola N; Haferlach, Torsten T; Kern, Wolfgang W; Hartmann, Wolfgang W; Klapper, Wolfram W; Oschlies, Ilske I; Richter, Julia J; Kontny, Udo U; Lutz, Mathias M; Maecker-Kolhoff, Britta B; Ott, German G; Rosenwald, Andreas A; Siebert, Reiner R; von Stackelberg, Arend A; Strahm, Brigitte B; Woessmann, Wilhelm W; Zimmermann, Martin M; Zapukhlyak, Myroslav M; Grau, Michael M; Lenz, Georg G
Publication Date: 2022-07-06

Variant appearance in text: PTEN: 29G>A; S10N
PubMed Link: 35794096
Variant Present in the following documents:
  • 41467_2022_31355_MOESM5_ESM.xlsx, sheet 2
View BVdb publication page



Somatic targeted mutation profiling of colorectal cancer precursor lesions.

Bmc Medical Genomics
Dos Santos, Wellington W; Dos Reis, Mariana Bisarro MB; Porto, Jun J; de Carvalho, Ana Carolina AC; Matsushita, Marcus M; Oliveira, Gabriela G; Syrjänen, Kari K; Reis, Rui Manuel RM; Guimarães, Denise Peixoto DP
Publication Date: 2022-06-28

Variant appearance in text: PTEN: Ser10Asn
PubMed Link: 35761395
Variant Present in the following documents:
  • 12920_2022_1294_MOESM6_ESM.xlsx, sheet 1
  • 12920_2022_1294_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



A genetically distinct pediatric subtype of primary CNS large B-cell lymphoma is associated with favorable clinical outcome.

Blood Advances
Güney, Ekin E; Lucas, Calixto-Hope G CG; Qi, Zhongxia Z; Yu, Jingwei J; Zhang, Ruth R; Ohgami, Robert S RS; Rubenstein, James L JL; Boué, Daniel R DR; Schafernak, Kristian K; Wertheim, Gerald B GB; Dahiya, Sonika S; Giulino-Roth, Lisa L; Attarbaschi, Andishe A; Barth, Matthew J MJ; Kothari, Shalin S; Abla, Oussama O; Cohen, Adam L AL; Mendez, Joe S JS; Bollen, Andrew A; Perry, Arie A; Tihan, Tarik T; Pekmezci, Melike M; Solomon, David A DA; Wen, Kwun Wah KW
Publication Date: 2022-05-24

Variant appearance in text: PTEN: 29G>A; S10N
PubMed Link: 35157770
Variant Present in the following documents:
  • advancesADV2021006018-suppl1.pdf
View BVdb publication page



A pilot study of the use of dynamic analysis of cell-free DNA from aqueous humor and vitreous fluid for the diagnosis and treatment monitoring of vitreoretinal lymphomas.

Haematologica
Wang, Xiaoxiao X; Su, Wenru W; Gao, Yan Y; Feng, Yanfen Y; Wang, Xiaoxia X; Chen, Xiaoqing X; Hu, Yunwei Y; Ma, Yutong Y; Ou, Qiuxiang Q; Liang, Dan D; Huang, Huiqiang H
Publication Date: 2022-09-01

Variant appearance in text: PTEN: S10N
PubMed Link: 35142151
Variant Present in the following documents:
  • 2021_279908_WANG_TABS3.xlsx, sheet 1
View BVdb publication page



Mechanism of activation and the rewired network: New drug design concepts.

Medicinal Research Reviews
Nussinov, Ruth R; Zhang, Mingzhen M; Maloney, Ryan R; Tsai, Chung-Jung CJ; Yavuz, Bengi Ruken BR; Tuncbag, Nurcan N; Jang, Hyunbum H
Publication Date: 2022-03

Variant appearance in text: PTEN: S10N
PubMed Link: 34693559
Variant Present in the following documents:
  • Main text
  • MED-42-770.pdf
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: PTEN: S10N
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer
Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA
Publication Date: 2021-05

Variant appearance in text: PTEN: 29G>A; S10N
PubMed Link: 33704917
Variant Present in the following documents:
  • TCA-12-1271-s003.xls, sheet 1
View BVdb publication page



Phosphorylation and Driver Mutations in PI3Kα and PTEN Autoinhibition.

Molecular Cancer Research : Mcr
Nussinov, Ruth R; Zhang, Mingzhen M; Tsai, Chung-Jung CJ; Jang, Hyunbum H
Publication Date: 2021-04

Variant appearance in text: PTEN: S10N
PubMed Link: 33288731
Variant Present in the following documents:
  • Main text
View BVdb publication page



Utility of a custom designed next generation DNA sequencing gene panel to molecularly classify endometrial cancers according to The Cancer Genome Atlas subgroups.

Bmc Medical Genomics
Miller, Eirwen M EM; Patterson, Nicole E NE; Gressel, Gregory M GM; Karabakhtsian, Rouzan G RG; Bejerano-Sagie, Michal M; Ravi, Nivedita N; Maslov, Alexander A; Quispe-Tintaya, Wilber W; Wang, Tao T; Lin, Juan J; Smith, Harriet O HO; Goldberg, Gary L GL; Kuo, Dennis Y S DYS; Montagna, Cristina C
Publication Date: 2020-11-30

Variant appearance in text: PTEN: Ser10Asn
PubMed Link: 33256706
Variant Present in the following documents:
  • 12920_2020_824_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



Genetic markers and phosphoprotein forms of beta-catenin pβ-Cat552 and pβ-Cat675 are prognostic biomarkers of cervical cancer.

Ebiomedicine
Scholl, Suzy M SM; Beal, Jonas J; de Koning, Leanne L; Girard, Elodie E; Popovic, Marina M; de la Rochefordière, Anne A; Lecuru, Fabrice F; Fourchotte, Virginie V; Ngo, Charlotte C; Floquet, Anne A; Berns, Els Mjj EM; Kenter, Gemma G; Gestraud, Pierre P; von der Leyen, Heiko H; Lecerf, Charlotte C; Puard, Vincent V; Roman, Sergio Roman SR; Latouche, Aurelien A; Kereszt, Attila A; Balint, Balazs B; Rouzier, Roman R; Kamal, Maud M
Publication Date: 2020-11

Variant appearance in text: PTEN: 29G>A; S10N
PubMed Link: 33096476
Variant Present in the following documents:
  • mmc2.xlsx, sheet 1
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: PTEN: S10N
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



The Impact of Genetic Variants on PTEN Molecular Functions and Cellular Phenotypes.

Cold Spring Harbor Perspectives In Medicine
Hasle, Nicholas N; Matreyek, Kenneth A KA; Fowler, Douglas M DM
Publication Date: 2019-11-01

Variant appearance in text: PTEN: S10N
PubMed Link: 31451538
Variant Present in the following documents:
  • Main text
View BVdb publication page



Crosstalk between PKCα and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium.

Cell Reports
Hsu, Alice H AH; Lum, Michelle A MA; Shim, Kang-Sup KS; Frederick, Peter J PJ; Morrison, Carl D CD; Chen, Baojiang B; Lele, Subodh M SM; Sheinin, Yuri M YM; Daikoku, Takiko T; Dey, Sudhansu K SK; Leone, Gustavo G; Black, Adrian R AR; Black, Jennifer D JD
Publication Date: 2018-07-17

Variant appearance in text: PTEN: S10N
PubMed Link: 30021163
Variant Present in the following documents:
  • NIHMS1502991-supplement-1.pdf
  • NIHMS1502991-supplement-2.pdf
View BVdb publication page



Genetic alterations analysis in prognostic stratified groups identified TP53 and ARID1A as poor clinical performance markers in intrahepatic cholangiocarcinoma.

Scientific Reports
Simbolo, Michele M; Vicentini, Caterina C; Ruzzenente, Andrea A; Brunelli, Matteo M; Conci, Simone S; Fassan, Matteo M; Mafficini, Andrea A; Rusev, Borislav B; Corbo, Vincenzo V; Capelli, Paola P; Bria, Emilio E; Pedron, Serena S; Turri, Giona G; Lawlor, Rita T RT; Tortora, Giampaolo G; Bassi, Claudio C; Guglielmi, Alfredo A; Scarpa, Aldo A
Publication Date: 2018-05-08

Variant appearance in text: PTEN: Ser10Asn
PubMed Link: 29740198
Variant Present in the following documents:
  • 41598_2018_25669_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes.

Oncotarget
Lindqvist, C Mårten CM; Lundmark, Anders A; Nordlund, Jessica J; Freyhult, Eva E; Ekman, Diana D; Carlsson Almlöf, Jonas J; Raine, Amanda A; Övernäs, Elin E; Abrahamsson, Jonas J; Frost, Britt-Marie BM; Grandér, Dan D; Heyman, Mats M; Palle, Josefine J; Forestier, Erik E; Lönnerholm, Gudmar G; Berglund, Eva C EC; Syvänen, Ann-Christine AC
Publication Date: 2016-09-27

Variant appearance in text: PTEN: S10N
PubMed Link: 27590521
Variant Present in the following documents:
  • oncotarget-07-64071-s002.xlsx, sheet 4
View BVdb publication page



A Landscape of Pharmacogenomic Interactions in Cancer.

Cell
Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ
Publication Date: 2016-07-28

Variant appearance in text: PTEN: 29G>A; S10N
PubMed Link: 27397505
Variant Present in the following documents:
  • mmc3.xlsx, sheet 2
View BVdb publication page



PredictSNP2: A Unified Platform for Accurately Evaluating SNP Effects by Exploiting the Different Characteristics of Variants in Distinct Genomic Regions.

Plos Computational Biology
Bendl, Jaroslav J; Musil, Miloš M; Štourač, Jan J; Zendulka, Jaroslav J; Damborský, Jiří J; Brezovský, Jan J
Publication Date: 2016-05

Variant appearance in text: PTEN: S10N
PubMed Link: 27224906
Variant Present in the following documents:
  • pcbi.1004962.s005.xlsx, sheet 1
View BVdb publication page



Molecular Heterogeneity of Ewing Sarcoma as Detected by Ion Torrent Sequencing.

Plos One
Zhang, Nana N; Liu, Haijing H; Yue, Guanjun G; Zhang, Yan Y; You, Jiangfeng J; Wang, Hua H
Publication Date: 2016

Variant appearance in text: PTEN: 29G>A; Ser10Asn
PubMed Link: 27077911
Variant Present in the following documents:
  • pone.0153546.s004.xlsx, sheet 1
View BVdb publication page



GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics
Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J
Publication Date: 2015-07-25

Variant appearance in text: PTEN: S10N
PubMed Link: 26206375
Variant Present in the following documents:
  • 12859_2015_673_MOESM1_ESM.xls, sheet 1
View BVdb publication page



A functional dissection of PTEN N-terminus: implications in PTEN subcellular targeting and tumor suppressor activity.

Plos One
Gil, Anabel A; Rodríguez-Escudero, Isabel I; Stumpf, Miriam M; Molina, María M; Cid, Víctor J VJ; Pulido, Rafael R
Publication Date: 2015

Variant appearance in text: PTEN: S10N
PubMed Link: 25875300
Variant Present in the following documents:
  • Main text
View BVdb publication page



High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer.

Genome Biology
Tan, Iain Beehuat IB; Malik, Simeen S; Ramnarayanan, Kalpana K; McPherson, John R JR; Ho, Dan Liang DL; Suzuki, Yuka Y; Ng, Sarah Boonhsui SB; Yan, Su S; Lim, Kiat Hon KH; Koh, Dennis D; Hoe, Chew Min CM; Chan, Chung Yip CY; Ten, Rachel R; Goh, Brian Kp BK; Chung, Alexander Yf AY; Tan, Joanna J; Chan, Cheryl Xueli CX; Tay, Su Ting ST; Alexander, Lezhava L; Nagarajan, Niranjan N; Hillmer, Axel M AM; Tang, Choon Leong CL; Chua, Clarinda C; Teh, Bin Tean BT; Rozen, Steve S; Tan, Patrick P
Publication Date: 2015-02-12

Variant appearance in text: PTEN: S10N
PubMed Link: 25808843
Variant Present in the following documents:
  • 13059_2015_589_MOESM4_ESM.pdf
View BVdb publication page



Engineering PTEN function: membrane association and activity.

Methods (San Diego, Calif.)
Yang, Jr-Ming JM; Nguyen, Hoai-Nghia HN; Sesaki, Hiromi H; Devreotes, Peter N PN; Iijima, Miho M
Publication Date: 2015-05

Variant appearance in text: PTEN: S10N
PubMed Link: 25448479
Variant Present in the following documents:
  • Main text
View BVdb publication page



A new class of cancer-associated PTEN mutations defined by membrane translocation defects.

Oncogene
Nguyen, H-N HN; Yang, J-M JM; Rahdar, M M; Keniry, M M; Swaney, K F KF; Parsons, R R; Park, B H BH; Sesaki, H H; Devreotes, P N PN; Iijima, M M
Publication Date: 2015-07

Variant appearance in text: PTEN: S10N
PubMed Link: 25263454
Variant Present in the following documents:
  • Main text
  • nihms619140.pdf
  • NIHMS619140-supplement-2.pdf
View BVdb publication page



Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research
Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C
Publication Date: 2011-09-01

Variant appearance in text: PTEN: S10N
PubMed Link: 21727090
Variant Present in the following documents:
  • supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1
View BVdb publication page



PTEN and the PI3-kinase pathway in cancer.

Annual Review Of Pathology
Chalhoub, Nader N; Baker, Suzanne J SJ
Publication Date: 2009

Variant appearance in text: PTEN: S10N
PubMed Link: 18767981
Variant Present in the following documents:
  • Main text
View BVdb publication page



Protean PTEN: form and function.

American Journal Of Human Genetics
Waite, Kristin A KA; Eng, Charis C
Publication Date: 2002-04

Variant appearance in text: PTEN: S10N
PubMed Link: 11875759
Variant Present in the following documents:
  • Main text
View BVdb publication page