PTEN c.170T>C ;(p.L57S)

Variant ID: 10-89685275-T-C

NM_000314.4(PTEN):c.170T>C;(p.L57S)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Prevalence of Molecular Alterations in a Swiss Cohort of 512 Colorectal Carcinoma Patients by Targeted Next-Generation Sequencing Analysis in Routine Diagnostics.

Pathobiology : Journal Of Immunopathology, Molecular And Cellular Biology
Haefliger, Simon S; Marston, Katharina K; Alborelli, Ilaria I; Stauffer, Edouard-Jean EJ; Gugger, Mathias M; Jermann, Philip M PM; Hoeller, Sylvia S; Tornillo, Luigi L; Terracciano, Luigi M LM; Bihl, Michel M; Matter, Matthias S MS
Publication Date: 2022-10-06

Variant appearance in text: PTEN: L57S
PubMed Link: 36202073
Variant Present in the following documents:
  • pat-0090-0166-s01.pdf
View BVdb publication page



Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer
Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA
Publication Date: 2021-05

Variant appearance in text: PTEN: 170T>C; L57S
PubMed Link: 33704917
Variant Present in the following documents:
  • TCA-12-1271-s003.xls, sheet 1
View BVdb publication page



Predictive Biomarkers for Immune Checkpoint Inhibitors in Metastatic Breast Cancer.

Cancer Medicine
Sivapiragasam, Abirami A; Ashok Kumar, Prashanth P; Sokol, Ethan S ES; Albacker, Lee A LA; Killian, Jonathan K JK; Ramkissoon, Shakti H SH; Huang, Richard S P RSP; Severson, Eric A EA; Brown, Charlotte A CA; Danziger, Natalie N; McGregor, Kimberly K; Ross, Jeffrey S JS
Publication Date: 2021-01

Variant appearance in text: PTEN: L57S
PubMed Link: 33314633
Variant Present in the following documents:
  • CAM4-10-53-s002.xlsx, sheet 1
View BVdb publication page



Presence of cancer-associated mutations in exhaled breath condensates of healthy individuals by next generation sequencing.

Oncotarget
Youssef, Omar O; Knuuttila, Aija A; Piirilä, Päivi P; Böhling, Tom T; Sarhadi, Virinder V; Knuutila, Sakari S
Publication Date: 2017-03-14

Variant appearance in text: PTEN: L57S
PubMed Link: 28199989
Variant Present in the following documents:
  • Main text
  • oncotarget-08-18166.pdf
View BVdb publication page



Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations.

Molecular Cancer Research : Mcr
Bianchi-Frias, Daniella D; Basom, Ryan R; Delrow, Jeffrey J JJ; Coleman, Ilsa M IM; Dakhova, Olga O; Qu, Xiaoyu X; Fang, Min M; Franco, Omar E OE; Ericson, Nolan G NG; Bielas, Jason H JH; Hayward, Simon W SW; True, Lawrence L; Morrissey, Colm C; Brown, Lisha L; Bhowmick, Neil A NA; Rowley, David D; Ittmann, Michael M; Nelson, Peter S PS
Publication Date: 2016-04

Variant appearance in text: PTEN: L57S
PubMed Link: 26753621
Variant Present in the following documents:
  • Main text
View BVdb publication page



Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research
Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C
Publication Date: 2011-09-01

Variant appearance in text: PTEN: L57S
PubMed Link: 21727090
Variant Present in the following documents:
  • supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1
View BVdb publication page



PTEN is a target of chromosome 10q loss in anaplastic oligodendrogliomas and PTEN alterations are associated with poor prognosis.

The American Journal Of Pathology
Sasaki, H H; Zlatescu, M C MC; Betensky, R A RA; Ino, Y Y; Cairncross, J G JG; Louis, D N DN
Publication Date: 2001-07

Variant appearance in text: PTEN: 170T>C; Leu57Ser
PubMed Link: 11438483
Variant Present in the following documents:
  • Main text
View BVdb publication page