PTEN c.247T>A ;(p.C83S)

Variant ID: 10-89690840-T-A

NM_000314.4(PTEN):c.247T>A;(p.C83S)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


Genomic and microenvironmental landscape of stage I follicular lymphoma, compared with stage III/IV.

Blood Advances
Los-de Vries, G Tjitske GT; Stevens, Wendy B C WBC; van Dijk, Erik E; Langois-Jacques, Carole C; Clear, Andrew J AJ; Stathi, Phylicia P; Roemer, Margaretha G M MGM; Mendeville, Matias M; Hijmering, Nathalie J NJ; Sander, Birgitta B; Rosenwald, Andreas A; Calaminici, Maria M; Hoster, Eva E; Hiddemann, Wolfgang W; Gaulard, Philippe P; Salles, Gilles G; Horn, Heike H; Klapper, Wolfram W; Xerri, Luc L; Burton, Catherine C; Tooze, Reuben M RM; Smith, Alexandra G AG; Buske, Christian C; Scott, David W DW; Natkunam, Yasodha Y; Advani, Ranjana R; Sehn, Laurie H LH; Raemaekers, John J; Gribben, John J; Kimby, Eva E; Kersten, Marie José MJ; Maucort-Boulch, Delphine D; Ylstra, Bauke B; de Jong, Daphne D
Publication Date: 2022-09-27

Variant appearance in text: PTEN: C83S
PubMed Link: 35816682
Variant Present in the following documents:
  • advancesADV2022008355-suppl2.xlsx, sheet 11
View BVdb publication page



NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis.

Oncogene
Luiken, Sarah S; Fraas, Angelika A; Bieg, Matthias M; Sugiyanto, Raisatun R; Goeppert, Benjamin B; Singer, Stephan S; Ploeger, Carolin C; Warsow, Gregor G; Marquardt, Jens U JU; Sticht, Carsten C; De La Torre, Carolina C; Pusch, Stefan S; Mehrabi, Arianeb A; Gretz, Norbert N; Schlesner, Matthias M; Eils, Roland R; Schirmacher, Peter P; Longerich, Thomas T; Roessler, Stephanie S
Publication Date: 2020-04

Variant appearance in text: PTEN: 247T>A; C83S
PubMed Link: 32055024
Variant Present in the following documents:
  • 41388_2020_1198_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



PARK2 loss promotes cancer progression via redox-mediated inactivation of PTEN.

Molecular & Cellular Oncology
Gupta, Amit A; Anjomani-Virmouni, Sara S; Koundouros, Nikos N; Poulogiannis, George G
Publication Date: 2017

Variant appearance in text: PTEN: C83S
PubMed Link: 29209642
Variant Present in the following documents:
  • Main text
  • kmco-04-06-1329692.pdf
View BVdb publication page



Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications
Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ
Publication Date: 2017-08-04

Variant appearance in text: PTEN: 247T>A; C83S
PubMed Link: 28775315
Variant Present in the following documents:
  • 41467_2017_289_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Protein S-sulfhydration by hydrogen sulfide in cardiovascular system.

British Journal Of Pharmacology
Meng, Guoliang G; Zhao, Shuang S; Xie, Liping L; Han, Yi Y; Ji, Yong Y
Publication Date: 2018-04

Variant appearance in text: PTEN: C83S
PubMed Link: 28432761
Variant Present in the following documents:
  • Main text
View BVdb publication page



PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation.

Molecular Cell
Gupta, Amit A; Anjomani-Virmouni, Sara S; Koundouros, Nikos N; Dimitriadi, Maria M; Choo-Wing, Rayman R; Valle, Adamo A; Zheng, Yuxiang Y; Chiu, Yu-Hsin YH; Agnihotri, Sameer S; Zadeh, Gelareh G; Asara, John M JM; Anastasiou, Dimitrios D; Arends, Mark J MJ; Cantley, Lewis C LC; Poulogiannis, George G
Publication Date: 2017-03-16

Variant appearance in text: PTEN: C83S
PubMed Link: 28306514
Variant Present in the following documents:
  • Main text
  • mmc1.pdf
  • mmc4.pdf
  • main.pdf
View BVdb publication page



Peroxidase activation of cytoglobin by anionic phospholipids: Mechanisms and consequences.

Biochimica Et Biophysica Acta
Tejero, Jesús J; Kapralov, Alexandr A AA; Baumgartner, Matthew P MP; Sparacino-Watkins, Courtney E CE; Anthonymutu, Tamil S TS; Vlasova, Irina I II; Camacho, Carlos J CJ; Gladwin, Mark T MT; Bayir, Hülya H; Kagan, Valerian E VE
Publication Date: 2016-05

Variant appearance in text: PTEN: Cys83Ser
PubMed Link: 26928591
Variant Present in the following documents:
  • Main text
View BVdb publication page



Protein glutathionylation in the regulation of peroxiredoxins: a family of thiol-specific peroxidases that function as antioxidants, molecular chaperones, and signal modulators.

Antioxidants & Redox Signaling
Chae, Ho Zoon HZ; Oubrahim, Hammou H; Park, Ji Won JW; Rhee, Sue Goo SG; Chock, P Boon PB
Publication Date: 2012-03-15

Variant appearance in text: PTEN: C83S
PubMed Link: 22114845
Variant Present in the following documents:
  • Main text
View BVdb publication page



On-off system for PI3-kinase-Akt signaling through S-nitrosylation of phosphatase with sequence homology to tensin (PTEN).

Proceedings Of The National Academy Of Sciences Of The United States Of America
Numajiri, Naoki N; Takasawa, Kumi K; Nishiya, Tadashi T; Tanaka, Hirotaka H; Ohno, Kazuki K; Hayakawa, Wataru W; Asada, Mariko M; Matsuda, Hiromi H; Azumi, Kaoru K; Kamata, Hideaki H; Nakamura, Tomohiro T; Hara, Hideaki H; Minami, Masabumi M; Lipton, Stuart A SA; Uehara, Takashi T
Publication Date: 2011-06-21

Variant appearance in text: PTEN: C83S
PubMed Link: 21646525
Variant Present in the following documents:
  • Main text
View BVdb publication page



Peroxiredoxin 1 and its role in cell signaling.

Cell Cycle (Georgetown, Tex.)
Neumann, Carola A CA; Cao, Juxiang J; Manevich, Yefim Y
Publication Date: 2009-12-15

Variant appearance in text: PTEN: Cys83Ser
PubMed Link: 19923889
Variant Present in the following documents:
  • Main text
View BVdb publication page