PTEN c.490A>G ;(p.K164E)

Variant ID: 10-89693006-A-G

NM_000314.4(PTEN):c.490A>G;(p.K164E)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Molecular correlates and therapeutic targets in T cell-inflamed versus non-T cell-inflamed tumors across cancer types.

Genome Medicine
Bao, Riyue R; Stapor, Daniel D; Luke, Jason J JJ
Publication Date: 2020-10-27

Variant appearance in text: PTEN: K164E
PubMed Link: 33106165
Variant Present in the following documents:
  • 13073_2020_787_MOESM1_ESM.xlsx, sheet 9
View BVdb publication page



PI3K Driver Mutations: A Biophysical Membrane-Centric Perspective.

Cancer Research
Zhang, Mingzhen M; Jang, Hyunbum H; Nussinov, Ruth R
Publication Date: 2021-01-15

Variant appearance in text: PTEN: K164E
PubMed Link: 33046444
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Landscape of Pharmacogenomic Interactions in Cancer.

Cell
Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ
Publication Date: 2016-07-28

Variant appearance in text: PTEN: 490A>G; K164E
PubMed Link: 27397505
Variant Present in the following documents:
  • mmc3.xlsx, sheet 2
View BVdb publication page



Interactions of phosphatase and tensin homologue (PTEN) proteins with phosphatidylinositol phosphates: insights from molecular dynamics simulations of PTEN and voltage sensitive phosphatase.

Biochemistry
Kalli, Antreas C AC; Devaney, Isabel I; Sansom, Mark S P MS
Publication Date: 2014-03-25

Variant appearance in text: PTEN: K164E
PubMed Link: 24588644
Variant Present in the following documents:
  • Main text
  • bi5000299.pdf
View BVdb publication page



Defining the membrane-associated state of the PTEN tumor suppressor protein.

Biophysical Journal
Lumb, Craig N CN; Sansom, Mark S P MS
Publication Date: 2013-02-05

Variant appearance in text: PTEN: K164E
PubMed Link: 23442912
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mutations in Rb1 pathway-related genes are associated with poor prognosis in anaplastic astrocytomas.

British Journal Of Cancer
Bäcklund, L M LM; Nilsson, B R BR; Liu, L L; Ichimura, K K; Collins, V P VP
Publication Date: 2005-07-11

Variant appearance in text: PTEN: K164E
PubMed Link: 15970925
Variant Present in the following documents:
  • Main text
  • 93-6602661a.pdf
View BVdb publication page