PTEN c.493-6446G>C

Variant ID: 10-89705429-G-C

NM_000314.4(PTEN):c.493-6446G>C

This variant was identified in 16 publications

View GRCh38 version.




Publications:


Pharmacogenetics of anticancer monoclonal antibodies.

Cancer Drug Resistance (Alhambra, Calif.)
Shek, Dmitrii D; Read, Scott A SA; Ahlenstiel, Golo G; Piatkov, Irina I
Publication Date: 2019

Variant appearance in text: rs2735343
PubMed Link: 35582142
Variant Present in the following documents:
  • cdr-2-69.pdf
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Two tSNPs in BRIP1 are associated with breast cancer during TDT analysis.

Molecular Genetics & Genomic Medicine
Li, Xuefei X; Li, Zhuo Z; Yang, Miao M; Luo, Yan Y; Hu, Li L; Xiao, Zhi Z; Huang, Aji A; Huang, Juan J
Publication Date: 2021-02

Variant appearance in text: rs2735343
PubMed Link: 33403820
Variant Present in the following documents:
  • Main text
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A Novel Network Pharmacology Strategy to Decode Metabolic Biomarkers and Targets Interactions for Depression.

Frontiers In Psychiatry
Gao, Yao Y; Xu, Teng T; Zhao, Ying-Xia YX; Ling-Hu, Ting T; Liu, Shao-Bo SB; Tian, Jun-Sheng JS; Qin, Xue-Mei XM
Publication Date: 2020

Variant appearance in text: rs2735343
PubMed Link: 32760300
Variant Present in the following documents:
  • Main text
  • fpsyt-11-00667.pdf
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A genome-wide scan for pleiotropy between bone mineral density and nonbone phenotypes.

Bone Research
Christou, Maria A MA; Ntritsos, Georgios G; Markozannes, Georgios G; Koskeridis, Fotis F; Nikas, Spyros N SN; Karasik, David D; Kiel, Douglas P DP; Evangelou, Evangelos E; Ntzani, Evangelia E EE
Publication Date: 2020

Variant appearance in text: rs2735343
PubMed Link: 32637184
Variant Present in the following documents:
  • Main text
  • 41413_2020_Article_101.pdf
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Association of polymorphisms of PTEN, AKT1, PI3K, AR, and AMACR genes in patients with prostate cancer.

Genetics And Molecular Biology
Nóbrega, Monyse de M; Cilião, Heloisa Lizotti HL; Souza, Marilesia Ferreira de MF; Souza, Milene Roldão de MR; Serpeloni, Juliana Mara JM; Fuganti, Paulo Emilio PE; Cólus, Ilce Mara de Syllos IMS
Publication Date: 2020-06-01

Variant appearance in text: rs2735343
PubMed Link: 32484847
Variant Present in the following documents:
  • Main text
  • 1415-4757-GMB-43-3-e20180329.pdf
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Association of Single-Nucleotide Polymorphisms in Monoubiquitinated FANCD2-DNA Damage Repair Pathway Genes With Breast Cancer in the Chinese Population.

Technology In Cancer Research & Treatment
Chen, Fei-Yu FY; Wang, Hao H; Li, Hui H; Hu, Xue-Li XL; Dai, Xu X; Wang, Shou-Man SM; Yan, Guo-Jiao GJ; Jiang, Ping-Lan PL; Hu, Yuan-Ping YP; Huang, Juan J; Tang, Li-Li LL
Publication Date: 2018-01-01

Variant appearance in text: rs2735343
PubMed Link: 30799775
Variant Present in the following documents:
  • Main text
  • 10.1177_1533033818819841.pdf
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Single nucleotide polymorphisms rs701848 and rs2735343 in PTEN increases cancer risks in an Asian population.

Oncotarget
Song, Dan-Dan DD; Zhang, Qian Q; Li, Jing-Hua JH; Hao, Rui-Min RM; Ma, Ying Y; Wang, Ping-Yu PY; Xie, Shu-Yang SY
Publication Date: 2017-11-10

Variant appearance in text: rs2735343
PubMed Link: 29221206
Variant Present in the following documents:
  • Main text
  • oncotarget-08-96290.pdf
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Unique Features of Germline Variation in Five Egyptian Familial Breast Cancer Families Revealed by Exome Sequencing.

Plos One
Kim, Yeong C YC; Soliman, Amr S AS; Cui, Jian J; Ramadan, Mohamed M; Hablas, Ahmed A; Abouelhoda, Mohamed M; Hussien, Nehal N; Ahmed, Ola O; Zekri, Abdel-Rahman Nabawy AN; Seifeldin, Ibrahim A IA; Wang, San Ming SM
Publication Date: 2017

Variant appearance in text: rs2735343
PubMed Link: 28076423
Variant Present in the following documents:
  • pone.0167581.s001.xlsx, sheet 1
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Genetic Modifiers of Patent Ductus Arteriosus in Term Infants.

The Journal Of Pediatrics
Patel, Priti M PM; Momany, Allison M AM; Schaa, Kendra L KL; Romitti, Paul A PA; Druschel, Charlotte C; Cooper, Margaret E ME; Marazita, Mary L ML; Murray, Jeffrey C JC; Dagle, John M JM
Publication Date: 2016-09

Variant appearance in text: rs2735343
PubMed Link: 27344223
Variant Present in the following documents:
  • Main text
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The study of the relation of DNA repair pathway genes SNPs and the sensitivity to radiotherapy and chemotherapy of NSCLC.

Scientific Reports
Wang, Chunbo C; Nie, Huan H; Li, Yiqun Y; Liu, Guiyou G; Wang, Xu X; Xing, Shijie S; Zhang, Liping L; Chen, Xin X; Chen, Yue Y; Li, Yu Y
Publication Date: 2016-06-01

Variant appearance in text: rs2735343
PubMed Link: 27246533
Variant Present in the following documents:
  • Main text
  • srep26526.pdf
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Influence of CHIEF pathway genes on gene expression: a pathway approach to functionality.

International Journal Of Molecular Epidemiology And Genetics
Slattery, Martha L ML; Lundgreen, Abbie A; Mullany, Lila E LE; Penney, Rosalind B RB; Wolff, Roger K RK
Publication Date: 2014

Variant appearance in text: rs2735343
PubMed Link: 24959314
Variant Present in the following documents:
  • Main text
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Loss of PTEN expression is associated with poor prognosis in patients with intraductal papillary mucinous neoplasms of the pancreas.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Garcia-Carracedo, Dario D; Turk, Andrew T AT; Fine, Stuart A SA; Akhavan, Nathan N; Tweel, Benjamin C BC; Parsons, Ramon R; Chabot, John A JA; Allendorf, John D JD; Genkinger, Jeanine M JM; Remotti, Helen E HE; Su, Gloria H GH
Publication Date: 2013-12-15

Variant appearance in text: rs2735343
PubMed Link: 24132918
Variant Present in the following documents:
  • Main text
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Genetic variation in genes involved in hormones, inflammation and energetic factors and breast cancer risk in an admixed population.

Carcinogenesis
Slattery, Martha L ML; John, Esther M EM; Torres-Mejia, Gabriela G; Lundgreen, Abbie A; Herrick, Jennifer S JS; Baumgartner, Kathy B KB; Hines, Lisa M LM; Stern, Mariana C MC; Wolff, Roger K RK
Publication Date: 2012-08

Variant appearance in text: rs2735343
PubMed Link: 22562547
Variant Present in the following documents:
  • Main text
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Germ-line sequence variants of PTEN do not have an important role in hereditary and non-hereditary prostate cancer susceptibility.

Journal Of Human Genetics
Xie, Chunmei C CC; Lu, Lingyi L; Sun, Jielin J; Zheng, S Lilly SL; Isaacs, William B WB; Gronberg, Henrik H; Xu, Jianfeng J
Publication Date: 2011-07

Variant appearance in text: rs2735343
PubMed Link: 21633361
Variant Present in the following documents:
  • Main text
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Endometrial cancer and genetic variation in PTEN, PIK3CA, AKT1, MLH1, and MSH2 within a population-based case-control study.

Gynecologic Oncology
Lacey, James V JV; Yang, Hannah H; Gaudet, Mia M MM; Dunning, Alison A; Lissowska, Jolanta J; Sherman, Mark E ME; Peplonska, Beata B; Brinton, Louise A LA; Healey, Catherine S CS; Ahmed, Shahana S; Pharoah, Paul P; Easton, Douglas D; Chanock, Stephen S; Garcia-Closas, Montserrat M
Publication Date: 2011-02

Variant appearance in text: rs2735343
PubMed Link: 21093899
Variant Present in the following documents:
  • Main text
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Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis.

Human Reproduction Update
Tempfer, C B CB; Simoni, M M; Destenaves, B B; Fauser, B C J M BC
Publication Date: 2009

Variant appearance in text: rs2735343
PubMed Link: 18805939
Variant Present in the following documents:
  • Main text
  • dmn040.pdf
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