Publications:

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p53 at the Crossroads between Doxorubicin-Induced Cardiotoxicity and Resistance: A Nutritional Balancing Act.

Nutrients

Guo, Yuanfang Y; Tang, Yufeng Y; Lu, Guangping G; Gu, Junlian J

Publication Date: 2023-05-10

Variant appearance in text: PTEN: R172H

PubMed Link: 37242146

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• Main text
• nutrients-15-02259.pdf

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TP53 Alterations in Myelodysplastic Syndromes and Acute Myeloid Leukemia.

Biomedicines

Rahmé, Ramy R; Braun, Thorsten T; Manfredi, James J JJ; Fenaux, Pierre P

Publication Date: 2023-04-11

Variant appearance in text: PTEN: R172H

PubMed Link: 37189770

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• Main text
• biomedicines-11-01152.pdf

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A strategy for the treatment of gastrointestinal cancer: Targeting tumor senescent cells.

Frontiers In Molecular Biosciences

Liu, Yujing Y; Zhang, Qiang Q; Ni, Wenjing W; Ji, Guang G; Xu, Hanchen H

Publication Date: 2023

Variant appearance in text: PTEN: R172H

PubMed Link: 36950520

Variant Present in the following documents:

• Main text
• fmolb-10-1139840.pdf

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Review of the endocrine organ-like tumor hypothesis of cancer cachexia in pancreatic ductal adenocarcinoma.

Frontiers In Oncology

Yu, Ying-Chun YC; Ahmed, Azaj A; Lai, Hsueh-Chou HC; Cheng, Wei-Chung WC; Yang, Juan-Chern JC; Chang, Wei-Chun WC; Chen, Lu-Min LM; Shan, Yan-Shen YS; Ma, Wen-Lung WL

Publication Date: 2022

Variant appearance in text: PTEN: R172H

PubMed Link: 36465353

Variant Present in the following documents:

• Main text

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Aberrant MAPK Signaling Offers Therapeutic Potential for Treatment of Ovarian Carcinoma.

Oncotargets And Therapy

Colic, Eva E; Patel, Preya U PU; Kent, Oliver A OA

Publication Date: 2022

Variant appearance in text: PTEN: R172H

PubMed Link: 36388156

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• Main text
• ott-15-1331.pdf

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Development of extrahepatic bile ducts and mechanisms of tumorigenesis: Lessons from mouse models.

Pathology International

Tomita, Hiroyuki H; Hara, Akira A

Publication Date: 2022-11-09

Variant appearance in text: PTEN: R172H

PubMed Link: 36349994

Variant Present in the following documents:

• Main text
• PIN-72-589.pdf

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Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss.

Cell Death & Disease

Mejía-Hernández, Javier Octavio JO; Keam, Simon P SP; Saleh, Reem R; Muntz, Fenella F; Fox, Stephen B SB; Byrne, David D; Kogan, Arielle A; Pang, Lokman L; Huynh, Jennifer J; Litchfield, Cassandra C; Caramia, Franco F; Lozano, Guillermina G; He, Hua H; You, James M JM; Sandhu, Shahneen S; Williams, Scott G SG; Haupt, Ygal Y; Haupt, Sue S

Publication Date: 2022-09-08

Variant appearance in text: PTEN: R172H

PubMed Link: 36075907

Variant Present in the following documents:

• Main text
• 41419_2022_Article_5211.pdf

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Targeting the mTOR Pathway for the Prevention of ER-Negative Breast Cancer.

Cancer Prevention Research (Philadelphia, Pa.)

Mazumdar, Abhijit A; Tahaney, William M WM; Hill, Jamal L JL; Zhang, Yun Y; Ramachandran, Sumankalai S; Kawedia, Jitesh J; Qian, Jing J; Contreras, Alejandro A; Savage, Michelle I MI; Vornik, Lana A LA; Sei, Shizuko S; Mohammed, Altaf A; Brown, Powel H PH

Publication Date: 2022-12-01

Variant appearance in text: PTEN: R172H

PubMed Link: 35981902

Variant Present in the following documents:

• Main text
• 791.pdf

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Autophagy: A Key Player in Pancreatic Cancer Progression and a Potential Drug Target.

Cancers

Gillson, Josef J; Abd El-Aziz, Yomna S YS; Leck, Lionel Y W LYW; Jansson, Patric J PJ; Pavlakis, Nick N; Samra, Jaswinder S JS; Mittal, Anubhav A; Sahni, Sumit S

Publication Date: 2022-07-20

Variant appearance in text: PTEN: R172H

PubMed Link: 35884592

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• Main text

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The microRNA-183/96/182 cluster inhibits lung cancer progression and metastasis by inducing an interleukin-2-mediated antitumor CD8+ cytotoxic T-cell response.

Genes & Development

Kundu, Samrat T ST; Rodriguez, B Leticia BL; Gibson, Laura A LA; Warner, Amanda N AN; Perez, Mabel G MG; Bajaj, Rakhee R; Fradette, Jared J JJ; Class, Caleb A CA; Solis, Luisa M LM; Rojas Alvarez, Frank R FR; Wistuba, Ignacio I II; Diao, Lixia L; Chen, Fengju F; Sachdeva, Mohit M; Wang, Jing J; Kirsch, David G DG; Creighton, Chad J CJ; Gibbons, Don L DL

Publication Date: 2022-05-01

Variant appearance in text: PTEN: R172H

PubMed Link: 35654454

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• Main text

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Targeting extracellular matrix stiffness and mechanotransducers to improve cancer therapy.

Journal Of Hematology & Oncology

Jiang, Yangfu Y; Zhang, Hongying H; Wang, Jiao J; Liu, Yongliang Y; Luo, Ting T; Hua, Hui H

Publication Date: 2022-03-24

Variant appearance in text: PTEN: R172H

PubMed Link: 35331296

Variant Present in the following documents:

• Main text
• 13045_2022_Article_1252.pdf

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Exploiting macropinocytosis for drug delivery into KRAS mutant cancer.

Theranostics

Liu, Huiqin H; Qian, Feng F

Publication Date: 2022

Variant appearance in text: PTEN: R172H

PubMed Link: 35154489

Variant Present in the following documents:

• Main text

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Ubiquitous Aberration in Cholesterol Metabolism across Pancreatic Ductal Adenocarcinoma.

Metabolites

Gunda, Venugopal V; Genaro-Mattos, Thiago C TC; Kaushal, Jyoti B JB; Chirravuri-Venkata, Ramakanth R; Natarajan, Gopalakrishnan G; Mallya, Kavita K; Grandgenett, Paul M PM; Mirnics, Karoly K; Batra, Surinder K SK; Korade, Zeljka Z; Rachagani, Satyanarayana S

Publication Date: 2022-01-07

Variant appearance in text: PTEN: R172H

PubMed Link: 35050168

Variant Present in the following documents:

• metabolites-12-00047.pdf

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Ubiquitous Aberration in Cholesterol Metabolism across Pancreatic Ductal Adenocarcinoma.

Metabolites

Gunda, Venugopal V; Genaro-Mattos, Thiago C TC; Kaushal, Jyoti B JB; Chirravuri-Venkata, Ramakanth R; Natarajan, Gopalakrishnan G; Mallya, Kavita K; Grandgenett, Paul M PM; Mirnics, Karoly K; Batra, Surinder K SK; Korade, Zeljka Z; Rachagani, Satyanarayana S

Publication Date: 2022-01-07

Variant appearance in text: PTEN: R172H

PubMed Link: 35050168

Variant Present in the following documents:

• metabolites-12-00047.pdf

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Genetic Mutations of Pancreatic Cancer and Genetically Engineered Mouse Models.

Cancers

Saiki, Yuriko Y; Jiang, Can C; Ohmuraya, Masaki M; Furukawa, Toru T

Publication Date: 2021-12-24

Variant appearance in text: PTEN: R172H

PubMed Link: 35008235

Variant Present in the following documents:

• Main text

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Genetic Mutations of Pancreatic Cancer and Genetically Engineered Mouse Models.

Cancers

Saiki, Yuriko Y; Jiang, Can C; Ohmuraya, Masaki M; Furukawa, Toru T

Publication Date: 2021-12-24

Variant appearance in text: PTEN: R172H

PubMed Link: 35008235

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• Main text

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The Role of Toll-like Receptors (TLRs) Mediated Inflammation in Pancreatic Cancer Pathophysiology.

International Journal Of Molecular Sciences

Orlacchio, Arturo A; Mazzone, Pellegrino P

Publication Date: 2021-11-25

Variant appearance in text: PTEN: R172H

PubMed Link: 34884547

Variant Present in the following documents:

• Main text
• ijms-22-12743.pdf

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The Role of Toll-like Receptors (TLRs) Mediated Inflammation in Pancreatic Cancer Pathophysiology.

International Journal Of Molecular Sciences

Orlacchio, Arturo A; Mazzone, Pellegrino P

Publication Date: 2021-11-25

Variant appearance in text: PTEN: R172H

PubMed Link: 34884547

Variant Present in the following documents:

• Main text
• ijms-22-12743.pdf

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CRISPR and KRAS: a match yet to be made.

Journal Of Biomedical Science

Bender, Guzide G; Fahrioglu Yamaci, Rezan R; Taneri, Bahar B

Publication Date: 2021-11-15

Variant appearance in text: PTEN: R172H

PubMed Link: 34781949

Variant Present in the following documents:

• Main text
• 12929_2021_Article_772.pdf

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Ferroptosis: At the Crossroad of Gemcitabine Resistance and Tumorigenesis in Pancreatic Cancer.

International Journal Of Molecular Sciences

Yang, Jianhui J; Xu, Jin J; Zhang, Bo B; Tan, Zhen Z; Meng, Qingcai Q; Hua, Jie J; Liu, Jiang J; Wang, Wei W; Shi, Si S; Yu, Xianjun X; Liang, Chen C

Publication Date: 2021-10-10

Variant appearance in text: PTEN: R172H

PubMed Link: 34681603

Variant Present in the following documents:

• Main text

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Pancreatic Neuroendocrine Tumors: Molecular Mechanisms and Therapeutic Targets.

Cancers

Maharjan, Chandra K CK; Ear, Po Hien PH; Tran, Catherine G CG; Howe, James R JR; Chandrasekharan, Chandrikha C; Quelle, Dawn E DE

Publication Date: 2021-10-12

Variant appearance in text: PTEN: R172H

PubMed Link: 34680266

Variant Present in the following documents:

• Main text

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TGFβ Signaling in the Pancreatic Tumor Microenvironment.

Cancers

Principe, Daniel R DR; Timbers, Kaytlin E KE; Atia, Luke G LG; Koch, Regina M RM; Rana, Ajay A

Publication Date: 2021-10-11

Variant appearance in text: PTEN: R172H

PubMed Link: 34680235

Variant Present in the following documents:

• Main text

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Dual recombinase action in the normal and neoplastic mammary gland epithelium.

Scientific Reports

Rädler, Patrick D PD; Vistisen, Kerry K; Triplett, Aleata A AA; Dennaoui, Rayane R; Li, Yong Y; Shrestha, Hridaya H; Ferraiuolo, Rosa-Maria RM; Thangasamy, Amalraj A; Saur, Dieter D; Wagner, Kay-Uwe KU

Publication Date: 2021-10-21

Variant appearance in text: PTEN: R172H

PubMed Link: 34675248

Variant Present in the following documents:

• Main text
• 41598_2021_Article_231.pdf

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The Diverse Applications of Pancreatic Ductal Adenocarcinoma Organoids.

Cancers

Low, Ronnie Ren Jie RRJ; Lim, Wei Wen WW; Nguyen, Paul M PM; Lee, Belinda B; Christie, Michael M; Burgess, Antony W AW; Gibbs, Peter P; Grimmond, Sean M SM; Hollande, Frédéric F; Putoczki, Tracy L TL

Publication Date: 2021-10-04

Variant appearance in text: PTEN: R172H

PubMed Link: 34638463

Variant Present in the following documents:

• Main text

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Immune pathways and TP53 missense mutations are associated with longer survival in canine osteosarcoma.

Communications Biology

Das, Sunetra S; Idate, Rupa R; Regan, Daniel P DP; Fowles, Jared S JS; Lana, Susan E SE; Thamm, Douglas H DH; Gustafson, Daniel L DL; Duval, Dawn L DL

Publication Date: 2021-10-11

Variant appearance in text: PTEN: R172H

PubMed Link: 34635775

Variant Present in the following documents:

• Main text
• 42003_2021_Article_2683.pdf

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TP53 in Biology and Treatment of Osteosarcoma.

Cancers

Synoradzki, Kamil Jozef KJ; Bartnik, Ewa E; Czarnecka, Anna M AM; Fiedorowicz, Michał M; Firlej, Wiktoria W; Brodziak, Anna A; Stasinska, Agnieszka A; Rutkowski, Piotr P; Grieb, Paweł P

Publication Date: 2021-08-25

Variant appearance in text: PTEN: R172H

PubMed Link: 34503094

Variant Present in the following documents:

• Main text
• cancers-13-04284.pdf

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How to Better Understand the Influence of Host Genetics on Developing an Effective Immune Response to Thoracic Cancers.

Frontiers In Oncology

Behrouzfar, Kiarash K; Burton, Kimberley K; Mutsaers, Steve E SE; Morahan, Grant G; Lake, Richard A RA; Fisher, Scott A SA

Publication Date: 2021

Variant appearance in text: PTEN: R172H

PubMed Link: 34235080

Variant Present in the following documents:

• Main text
• fonc-11-679609.pdf

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FOXM1: A Multifunctional Oncoprotein and Emerging Therapeutic Target in Ovarian Cancer.

Cancers

Liu, Cassie C; Barger, Carter J CJ; Karpf, Adam R AR

Publication Date: 2021-06-19

Variant appearance in text: PTEN: R172H

PubMed Link: 34205406

Variant Present in the following documents:

• Main text

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The biological underpinnings of therapeutic resistance in pancreatic cancer.

Genes & Development

Beatty, Gregory L GL; Werba, Gregor G; Lyssiotis, Costas A CA; Simeone, Diane M DM

Publication Date: 2021-07-01

Variant appearance in text: PTEN: R172H

PubMed Link: 34117095

Variant Present in the following documents:

• 940.pdf

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The biological underpinnings of therapeutic resistance in pancreatic cancer.

Genes & Development

Beatty, Gregory L GL; Werba, Gregor G; Lyssiotis, Costas A CA; Simeone, Diane M DM

Publication Date: 2021-07-01

Variant appearance in text: PTEN: R172H

PubMed Link: 34117095

Variant Present in the following documents:

• 940.pdf

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KRAS Mutation Dictates the Cancer Immune Environment in Pancreatic Ductal Adenocarcinoma and Other Adenocarcinomas.

Cancers

Gu, Meichen M; Gao, Yanli Y; Chang, Pengyu P

Publication Date: 2021-05-18

Variant appearance in text: PTEN: R172H

PubMed Link: 34069772

Variant Present in the following documents:

• Main text

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Coagulation Signaling through PAR1 as a Therapeutic Target in Pancreatic Ductal Adenocarcinoma.

International Journal Of Molecular Sciences

Kothari, Aditi A; Flick, Matthew J MJ

Publication Date: 2021-05-12

Variant appearance in text: PTEN: R172H

PubMed Link: 34066284

Variant Present in the following documents:

• Main text

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Pancreatic cancer intrinsic PI3Kα activity accelerates metastasis and rewires macrophage component.

Embo Molecular Medicine

Thibault, Benoit B; Ramos-Delgado, Fernanda F; Pons-Tostivint, Elvire E; Therville, Nicole N; Cintas, Celia C; Arcucci, Silvia S; Cassant-Sourdy, Stephanie S; Reyes-Castellanos, Gabriela G; Tosolini, Marie M; Villard, Amelie V AV; Cayron, Coralie C; Baer, Romain R; Bertrand-Michel, Justine J; Pagan, Delphine D; Ferreira Da Mota, Dina D; Yan, Hongkai H; Falcomatà, Chiara C; Muscari, Fabrice F; Bournet, Barbara B; Delord, Jean-Pierre JP; Aksoy, Ezra E; Carrier, Alice A; Cordelier, Pierre P; Saur, Dieter D; Basset, Celine C; Guillermet-Guibert, Julie J

Publication Date: 2021-07-07

Variant appearance in text: PTEN: R172H

PubMed Link: 34033220

Variant Present in the following documents:

• EMMM-13-e13502-s003.xlsx, sheet 2

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Therapeutic potential of microbial modulation in pancreatic cancer.

Gut

Chandra, Vidhi V; McAllister, Florencia F

Publication Date: 2021-04-27

Variant appearance in text: PTEN: R172H

PubMed Link: 33906958

Variant Present in the following documents:

• Main text

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Cellular models of development of ovarian high-grade serous carcinoma: A review of cell of origin and mechanisms of carcinogenesis.

Cell Proliferation

Mei, Jie J; Tian, Huixiang H; Huang, Hsuan-Shun HS; Hsu, Che-Fang CF; Liou, Yuligh Y; Wu, Nayiyuan N; Zhang, Wei W; Chu, Tang-Yuan TY

Publication Date: 2021-05

Variant appearance in text: PTEN: R172H

PubMed Link: 33768671

Variant Present in the following documents:

• Main text

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Implementation of CRISPR/Cas9 Genome Editing to Generate Murine Lung Cancer Models That Depict the Mutational Landscape of Human Disease.

Frontiers In Cell And Developmental Biology

Hartmann, Oliver O; Reissland, Michaela M; Maier, Carina R CR; Fischer, Thomas T; Prieto-Garcia, Cristian C; Baluapuri, Apoorva A; Schwarz, Jessica J; Schmitz, Werner W; Garrido-Rodriguez, Martin M; Pahor, Nikolett N; Davies, Clare C CC; Bassermann, Florian F; Orian, Amir A; Wolf, Elmar E; Schulze, Almut A; Calzado, Marco A MA; Rosenfeldt, Mathias T MT; Diefenbacher, Markus E ME

Publication Date: 2021

Variant appearance in text: PTEN: R172H

PubMed Link: 33738287

Variant Present in the following documents:

• Main text

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Mitophagy in Pancreatic Cancer.

Frontiers In Oncology

Xie, Yangchun Y; Liu, Jiao J; Kang, Rui R; Tang, Daolin D

Publication Date: 2021

Variant appearance in text: PTEN: R172H

PubMed Link: 33718171

Variant Present in the following documents:

• Main text

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Molecular Alterations in Pancreatic Cancer: Transfer to the Clinic.

International Journal Of Molecular Sciences

Rodríguez Gil, Yolanda Y; Jiménez Sánchez, Paula P; Muñoz Velasco, Raúl R; García García, Ana A; Sánchez-Arévalo Lobo, Víctor Javier VJ

Publication Date: 2021-02-19

Variant appearance in text: PTEN: R172H

PubMed Link: 33669845

Variant Present in the following documents:

• Main text

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Pancreatic Tumorigenesis: Oncogenic KRAS and the Vulnerability of the Pancreas to Obesity.

Cancers

Luo, Yongde Y; Li, Xiaokun X; Ma, Jianjia J; Abbruzzese, James L JL; Lu, Weiqin W

Publication Date: 2021-02-13

Variant appearance in text: PTEN: R172H

PubMed Link: 33668583

Variant Present in the following documents:

• Main text

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Mutant p53 as a Regulator and Target of Autophagy.

Frontiers In Oncology

Shi, Yong Y; Norberg, Erik E; Vakifahmetoglu-Norberg, Helin H

Publication Date: 2020

Variant appearance in text: PTEN: R172H

PubMed Link: 33614491

Variant Present in the following documents:

• Main text

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Relaxin gene delivery modulates macrophages to resolve cancer fibrosis and synergizes with immune checkpoint blockade therapy.

Science Advances

Zhou, Xuefei X; Liu, Yun Y; Hu, Mengying M; Wang, Menglin M; Liu, Xiangrui X; Huang, Leaf L

Publication Date: 2021-02

Variant appearance in text: PTEN: R172H

PubMed Link: 33597232

Variant Present in the following documents:

• Main text

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Comprehensive Review of Methodology to Detect Reactive Oxygen Species (ROS) in Mammalian Species and Establish Its Relationship with Antioxidants and Cancer.

Antioxidants (Basel, Switzerland)

Fuloria, Shivkanya S; Subramaniyan, Vetriselvan V; Karupiah, Sundram S; Kumari, Usha U; Sathasivam, Kathiresan K; Meenakshi, Dhanalekshmi Unnikrishnan DU; Wu, Yuan Seng YS; Sekar, Mahendran M; Chitranshi, Nitin N; Malviya, Rishabha R; Sudhakar, Kalvatala K; Bajaj, Sakshi S; Fuloria, Neeraj Kumar NK

Publication Date: 2021-01-18

Variant appearance in text: PTEN: R172H

PubMed Link: 33477494

Variant Present in the following documents:

• Main text

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Genetic and stochastic influences upon tumor formation and tumor types in Li-Fraumeni mouse models.

Life Science Alliance

Chan, Chang S CS; Sun, Yvonne Y; Ke, Hua H; Zhao, Yuhan Y; Belete, Merzu M; Zhang, Cen C; Feng, Zhaohui Z; Levine, Arnold J AJ; Hu, Wenwei W

Publication Date: 2021-03

Variant appearance in text: PTEN: R172H

PubMed Link: 33376133

Variant Present in the following documents:

• Main text

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Mutant p53 drives the loss of heterozygosity by the upregulation of Nek2 in breast cancer cells.

Breast Cancer Research : Bcr

Ghaleb, Amr A; Padellan, Malik M; Marchenko, Natalia N

Publication Date: 2020-12-02

Variant appearance in text: PTEN: R172H

PubMed Link: 33267874

Variant Present in the following documents:

• 13058_2020_Article_1370.pdf

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Plant-Derived Natural Products in Cancer Research: Extraction, Mechanism of Action, and Drug Formulation.

Molecules (Basel, Switzerland)

Talib, Wamidh H WH; Alsalahat, Izzeddin I; Daoud, Safa S; Abutayeh, Reem Fawaz RF; Mahmod, Asma Ismail AI

Publication Date: 2020-11-14

Variant appearance in text: PTEN: R172H

PubMed Link: 33202681

Variant Present in the following documents:

• Main text

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Regulation of PD-L1 expression in K-ras-driven cancers through ROS-mediated FGFR1 signaling.

Redox Biology

Glorieux, Christophe C; Xia, Xiaojun X; He, Yong-Qiao YQ; Hu, Yumin Y; Cremer, Kelly K; Robert, Annie A; Liu, Junchen J; Wang, Fen F; Ling, Jianhua J; Chiao, Paul J PJ; Huang, Peng P

Publication Date: 2021-01

Variant appearance in text: PTEN: R172H

PubMed Link: 33171331

Variant Present in the following documents:

• Main text

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Cannabidiol (CBD) as a Promising Anti-Cancer Drug.

Cancers

Seltzer, Emily S ES; Watters, Andrea K AK; MacKenzie, Danny D; Granat, Lauren M LM; Zhang, Dong D

Publication Date: 2020-10-30

Variant appearance in text: PTEN: R172H

PubMed Link: 33143283

Variant Present in the following documents:

• Main text

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Attenuation of p53 mutant as an approach for treatment Her2-positive cancer.

Cell Death Discovery

Fedorova, Olga O; Daks, Alexandra A; Shuvalov, Oleg O; Kizenko, Alena A; Petukhov, Alexey A; Gnennaya, Yulia Y; Barlev, Nikolai N

Publication Date: 2020

Variant appearance in text: PTEN: R172H

PubMed Link: 33083021

Variant Present in the following documents:

• 41420_2020_Article_337.pdf

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Kras mutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer.

Laboratory Investigation; A Journal Of Technical Methods And Pathology

Singh, Kanchan K; Pruski, Melissa M; Bland, Rachael R; Younes, Mamoun M; Guha, Sushovan S; Thosani, Nirav N; Maitra, Anirban A; Cash, Brooks D BD; McAllister, Florencia F; Logsdon, Craig D CD; Chang, Jeffrey T JT; Bailey-Lundberg, Jennifer M JM

Publication Date: 2021-02

Variant appearance in text: PTEN: R172H

PubMed Link: 33009500

Variant Present in the following documents:

• Main text

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Bone morphogenetic protein 7 promotes resistance to immunotherapy.

Nature Communications

Cortez, Maria Angelica MA; Masrorpour, Fatemeh F; Ivan, Cristina C; Zhang, Jie J; Younes, Ahmed I AI; Lu, Yue Y; Estecio, Marcos R MR; Barsoumian, Hampartsoum B HB; Menon, Hari H; Caetano, Mauricio da Silva MDS; Ramapriyan, Rishab R; Schoenhals, Jonathan E JE; Wang, Xiaohong X; Skoulidis, Ferdinandos F; Wasley, Mark D MD; Calin, George G; Hwu, Patrick P; Welsh, James W JW

Publication Date: 2020-09-24

Variant appearance in text: PTEN: R172H

PubMed Link: 32973129

Variant Present in the following documents:

• Main text

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Preclinical mouse models for immunotherapeutic and non-immunotherapeutic drug development for pancreatic ductal adenocarcinoma.

Annals Of Pancreatic Cancer

He, Mengni M; Henderson, MacKenzie M; Muth, Stephen S; Murphy, Adrian A; Zheng, Lei L

Publication Date: 2020-07

Variant appearance in text: PTEN: R172H

PubMed Link: 32832900

Variant Present in the following documents:

• Main text

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Murine models of IDH-wild-type glioblastoma exhibit spatial segregation of tumor initiation and manifestation during evolution.

Nature Communications

Li, Yinghua Y; Li, Bo B; Li, Wei W; Wang, Yuan Y; Akgül, Seçkin S; Treisman, Daniel M DM; Heist, Kevin A KA; Pierce, Brianna R BR; Hoff, Benjamin B; Ho, Cheng-Ying CY; Ferguson, David O DO; Rehemtulla, Alnawaz A; Zheng, Siyuan S; Ross, Brian D BD; Li, Jun Z JZ; Zhu, Yuan Y

Publication Date: 2020-07-22

Variant appearance in text: PTEN: R172H

PubMed Link: 32699356

Variant Present in the following documents:

• Main text

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SOX2 and p53 Expression Control Converges in PI3K/AKT Signaling with Versatile Implications for Stemness and Cancer.

International Journal Of Molecular Sciences

Schaefer, Thorsten T; Steiner, Rebekah R; Lengerke, Claudia C

Publication Date: 2020-07-11

Variant appearance in text: PTEN: R172H

PubMed Link: 32664542

Variant Present in the following documents:

• Main text

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The Role of Dysfunctional Adipose Tissue in Pancreatic Cancer: A Molecular Perspective.

Cancers

Brocco, Davide D; Florio, Rosalba R; De Lellis, Laura L; Veschi, Serena S; Grassadonia, Antonino A; Tinari, Nicola N; Cama, Alessandro A

Publication Date: 2020-07-09

Variant appearance in text: PTEN: R172H

PubMed Link: 32659999

Variant Present in the following documents:

• Main text

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Oxidative Stress in Cancer.

Cancer Cell

Hayes, John D JD; Dinkova-Kostova, Albena T AT; Tew, Kenneth D KD

Publication Date: 2020-08-10

Variant appearance in text: PTEN: R172H

PubMed Link: 32649885

Variant Present in the following documents:

• Main text

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Modelling Epithelial Ovarian Cancer in Mice: Classical and Emerging Approaches.

International Journal Of Molecular Sciences

Zakarya, Razia R; Howell, Viive M VM; Colvin, Emily K EK

Publication Date: 2020-07-07

Variant appearance in text: PTEN: R172H

PubMed Link: 32645943

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Targeting DNA Damage Repair Pathways in Pancreatic Adenocarcinoma.

Current Treatment Options In Oncology

Das, Satya S; Cardin, Dana D

Publication Date: 2020-06-29

Variant appearance in text: PTEN: R172H

PubMed Link: 32601814

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Mutant p53 as an Antigen in Cancer Immunotherapy.

International Journal Of Molecular Sciences

Sobhani, Navid N; D'Angelo, Alberto A; Wang, Xu X; Young, Ken H KH; Generali, Daniele D; Li, Yong Y

Publication Date: 2020-06-08

Variant appearance in text: PTEN: R172H

PubMed Link: 32521648

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In vivo modeling of metastatic human high-grade serous ovarian cancer in mice.

Plos Genetics

Kim, Olga O; Park, Eun Young EY; Klinkebiel, David L DL; Pack, Svetlana D SD; Shin, Yong-Hyun YH; Abdullaev, Zied Z; Emerson, Robert E RE; Coffey, Donna M DM; Kwon, Sun Young SY; Creighton, Chad J CJ; Kwon, Sanghoon S; Chang, Edmund C EC; Chiang, Theodore T; Yatsenko, Alexander N AN; Chien, Jeremy J; Cheon, Dong-Joo DJ; Yang-Hartwich, Yang Y; Nakshatri, Harikrishna H; Nephew, Kenneth P KP; Behringer, Richard R RR; Fernández, Facundo M FM; Cho, Chi-Heum CH; Vanderhyden, Barbara B; Drapkin, Ronny R; Bast, Robert C RC; Miller, Kathy D KD; Karpf, Adam R AR; Kim, Jaeyeon J

Publication Date: 2020-06

Variant appearance in text: PTEN: R172H

PubMed Link: 32497036

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Mouse models of colorectal cancer: Past, present and future perspectives.

World Journal Of Gastroenterology

Bürtin, Florian F; Mullins, Christina S CS; Linnebacher, Michael M

Publication Date: 2020-04-07

Variant appearance in text: PTEN: R172H

PubMed Link: 32308343

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Macropinocytosis Renders a Subset of Pancreatic Tumor Cells Resistant to mTOR Inhibition.

Cell Reports

Michalopoulou, Evdokia E; Auciello, Francesca R FR; Bulusu, Vinay V; Strachan, David D; Campbell, Andrew D AD; Tait-Mulder, Jacqueline J; Karim, Saadia A SA; Morton, Jennifer P JP; Sansom, Owen J OJ; Kamphorst, Jurre J JJ

Publication Date: 2020-02-25

Variant appearance in text: PTEN: R172H

PubMed Link: 32101748

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Oncogenic Gain of Function in Glioblastoma Is Linked to Mutant p53 Amyloid Oligomers.

Iscience

Pedrote, Murilo M MM; Motta, Michelle F MF; Ferretti, Giulia D S GDS; Norberto, Douglas R DR; Spohr, Tania C L S TCLS; Lima, Flavia R S FRS; Gratton, Enrico E; Silva, Jerson L JL; de Oliveira, Guilherme A P GAP

Publication Date: 2020-02-21

Variant appearance in text: PTEN: R172H

PubMed Link: 31981923

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Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses.

Cell Reports

Blagih, Julianna J; Zani, Fabio F; Chakravarty, Probir P; Hennequart, Marc M; Pilley, Steven S; Hobor, Sebastijan S; Hock, Andreas K AK; Walton, Josephine B JB; Morton, Jennifer P JP; Gronroos, Eva E; Mason, Susan S; Yang, Ming M; McNeish, Iain I; Swanton, Charles C; Blyth, Karen K; Vousden, Karen H KH

Publication Date: 2020-01-14

Variant appearance in text: PTEN: R172H

PubMed Link: 31940491

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