PTEN c.516G>C ;(p.R172S)

Variant ID: 10-89711898-G-C

NM_000314.4(PTEN):c.516G>C;(p.R172S)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Genomic profiles of Indonesian colorectal cancer patients.

F1000Research
Abdullah, Murdani M; Meilany, Sofy S; Trimarsanto, Hidayat H; Malik, Safarina G SG; Sukartini, Ninik N; Idrus, Firhat F; Nursyirwan, Saskia A SA; Muzellina, Virly N VN; Pribadi, Rabbinu R RR; Utari, Amanda P AP; Maulahela, Hasan H; Syam, Ari F AF
Publication Date: 2022

Variant appearance in text: PTEN: R172S
PubMed Link: 37125020
Variant Present in the following documents:
  • f1000research-11-144370.pdf
View BVdb publication page



Targeted therapies for KRAS-mutant non-small cell lung cancer: from preclinical studies to clinical development-a narrative review.

Translational Lung Cancer Research
Santarpia, Mariacarmela M; Ciappina, Giuliana G; Spagnolo, Calogera Claudia CC; Squeri, Andrea A; Passalacqua, Maria Ilenia MI; Aguilar, Andrés A; Gonzalez-Cao, Maria M; Giovannetti, Elisa E; Silvestris, Nicola N; Rosell, Rafael R
Publication Date: 2023-02-28

Variant appearance in text: PTEN: R172S
PubMed Link: 36895930
Variant Present in the following documents:
  • Main text
  • tlcr-12-02-346.pdf
View BVdb publication page



Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging
Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M
Publication Date: 2022-05-25

Variant appearance in text: PTEN: 516G>C
PubMed Link: 35613927
Variant Present in the following documents:
  • aging-14-204101-s004.xlsx, sheet 1
View BVdb publication page



Genomic Analysis of Uterine Lavage Fluid Detects Early Endometrial Cancers and Reveals a Prevalent Landscape of Driver Mutations in Women without Histopathologic Evidence of Cancer: A Prospective Cross-Sectional Study.

Plos Medicine
Nair, Navya N; Camacho-Vanegas, Olga O; Rykunov, Dmitry D; Dashkoff, Matthew M; Camacho, Sandra Catalina SC; Schumacher, Cassie A CA; Irish, Jonathan C JC; Harkins, Timothy T TT; Freeman, Elijah E; Garcia, Isaac I; Pereira, Elena E; Kendall, Sviatoslav S; Belfer, Rachel R; Kalir, Tamara T; Sebra, Robert R; Reva, Boris B; Dottino, Peter P; Martignetti, John A JA
Publication Date: 2016-12

Variant appearance in text: PTEN: R172S
PubMed Link: 28027320
Variant Present in the following documents:
  • pmed.1002206.s017.xlsx, sheet 1
  • pmed.1002206.s015.xlsx, sheet 2
View BVdb publication page



Clinical Actionability of Comprehensive Genomic Profiling for Management of Rare or Refractory Cancers.

The Oncologist
Hirshfield, Kim M KM; Tolkunov, Denis D; Zhong, Hua H; Ali, Siraj M SM; Stein, Mark N MN; Murphy, Susan S; Vig, Hetal H; Vazquez, Alexei A; Glod, John J; Moss, Rebecca A RA; Belyi, Vladimir V; Chan, Chang S CS; Chen, Suzie S; Goodell, Lauri L; Foran, David D; Yelensky, Roman R; Palma, Norma A NA; Sun, James X JX; Miller, Vincent A VA; Stephens, Philip J PJ; Ross, Jeffrey S JS; Kaufman, Howard H; Poplin, Elizabeth E; Mehnert, Janice J; Tan, Antoinette R AR; Bertino, Joseph R JR; Aisner, Joseph J; DiPaola, Robert S RS; Rodriguez-Rodriguez, Lorna L; Ganesan, Shridar S
Publication Date: 2016-11

Variant appearance in text: PTEN: R172S
PubMed Link: 27566247
Variant Present in the following documents:
  • supp_the2016-0049_Supplemental_Tables.pdf
View BVdb publication page



Human germline and pan-cancer variomes and their distinct functional profiles.

Nucleic Acids Research
Pan, Yang Y; Karagiannis, Konstantinos K; Zhang, Haichen H; Dingerdissen, Hayley H; Shamsaddini, Amirhossein A; Wan, Quan Q; Simonyan, Vahan V; Mazumder, Raja R
Publication Date: 2014-10

Variant appearance in text: PTEN: R172S
PubMed Link: 25232094
Variant Present in the following documents:
  • Main text
View BVdb publication page



The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group.

Leukemia
Larson Gedman, A A; Chen, Q Q; Kugel Desmoulin, S S; Ge, Y Y; LaFiura, K K; Haska, C L CL; Cherian, C C; Devidas, M M; Linda, S B SB; Taub, J W JW; Matherly, L H LH
Publication Date: 2009-08

Variant appearance in text: PTEN: R172S
PubMed Link: 19340001
Variant Present in the following documents:
  • Main text
  • nihms98506.pdf
View BVdb publication page